DNA

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  Subject Areas on Research

  • "Smart" DNA interfaces. 
  • 'Interactive' recognition in EcoRI restriction enzyme-DNA complex. 
  • * CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. 
  • 172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant. 
  • 1H NMR spectroscopy of DNA. 
  • 2'-deoxy-5-azacytidine increases binding of cisplatin to DNA by a mechanism independent of DNA hypomethylation. 
  • 4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors. 
  • 5' flanking DNA sequences direct cell-specific expression of rat tyrosine hydroxylase. 
  • A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. 
  • A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter. 
  • A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication. 
  • A DNA deletion associated with multiple impaired transcripts in the visual mutant TRP. 
  • A DNA nanotransport device powered by polymerase phi29. 
  • A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. 
  • A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins. 
  • A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation. 
  • A candidate taste receptor gene near a sweet taste locus. 
  • A cis-acting sequence homologous to the yeast filamentation and invasion response element regulates expression of a pectinase gene from the bean pathogen Colletotrichum lindemuthianum. 
  • A combination DNA and attenuated simian immunodeficiency virus vaccine strategy provides enhanced protection from simian/human immunodeficiency virus-induced disease. 
  • A compound nucleotide repeat in the neurofibromatosis (NF1) gene. 
  • A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding. 
  • A de novo frame-shift mutation in the tuberin gene. 
  • A defined human system that supports bidirectional mismatch-provoked excision. 
  • A derivative of an ataxia-telangiectasia (A-T) cell line with normal radiosensitivity but A-T-like inhibition of DNA synthesis. 
  • A different life? 
  • A duplication in chromosome 4q35 is associated with hereditary benign intraepithelial dyskeratosis. 
  • A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery. 
  • A family of human Y chromosomes has dispersed throughout northern Eurasia despite a 1.8-Mb deletion in the azoospermia factor c region. 
  • A fragile X male with a broad smear on Southern blot analysis representing 100-500 CGG repeats and no methylation at the EagI site of the FMR-1 gene. 
  • A functional analysis of the spacer of V(D)J recombination signal sequences. 
  • A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain. 
  • A genetic association study of the mu opioid receptor and severe opioid dependence. 
  • A genome-wide survey of copy number variations in Han Chinese residing in Taiwan. 
  • A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. 
  • A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial. 
  • A high proportion of ADA point mutations associated with a specific alanine-to-valine substitution. 
  • A highly efficient strategy to determine genotypes of genetically-engineered mice using genomic DNA purified from hair roots. 
  • A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers. 
  • A historical account of Hoogsteen base-pairs in duplex DNA. 
  • A homozygous mutation in the endothelin-3 gene associated with a combined Waardenburg type 2 and Hirschsprung phenotype (Shah-Waardenburg syndrome). 
  • A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. 
  • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. 
  • A long-range flexible billboard model of gene activation. 
  • A maximum-likelihood base caller for DNA sequencing. 
  • A mixed epigenetic/genetic model for oligogenic inheritance of autism with a limited role for UBE3A. 
  • A monoclonal antibody (SZ21) specific for platelet GPIIIa distinguishes P1A1 from P1A2. 
  • A multimember kinesin gene family in Drosophila. 
  • A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells. 
  • A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro. 
  • A neural-specific GAP-43 core promoter located between unusual DNA elements that interact to regulate its activity. 
  • A neutrophil derived factor(s) stimulates [3H]thymidine incorporation by vascular smooth muscle cells in vitro. 
  • A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions. 
  • A new helper phospholipid for gene delivery. 
  • A new phase in the study of human inherited eye diseases. 
  • A new strategy for studying protein kinase B and its three isoforms. Role of protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin, WNK1, and ATP citrate lyase. 
  • A new tightly linked DNA probe for myotonic dystrophy. 
  • A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. 
  • A noncanonical function of cGAMP in inflammasome priming and activation. 
  • A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene. 
  • A novel beta-globin mutation, beta Durham-NC [beta 114 Leu-->Pro], produces a dominant thalassemia-like phenotype. 
  • A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. 
  • A novel polypeptide secreted by activated human T lymphocytes. 
  • A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. 
  • A novel process for optimizing musculoskeletal allograft tissue to improve safety, ultrastructural properties, and cell infiltration. 
  • A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs. 
  • A pathway-based classification of human breast cancer. 
  • A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation. 
  • A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia. 
  • A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice. 
  • A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair. 
  • A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci. 
  • A recombination-based assay demonstrates that the fragile X sequence is transcribed widely during development. 
  • A relocated technique of atomic force microscopy (AFM) samples and its application in molecular biology. 
  • A research for the relationship between human papillomavirus and human uterine cervical carcinoma. II. Molecular genetic and ultrastructural study on the transforming activity of recombinant retrovirus containing human papillomavirus type 16 subgenomic sequences. 
  • A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus. 
  • A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection. 
  • A serial study of splenic reticuloendothelial system Fc receptor functional activity in systemic lupus erythematosus. 
  • A simple BASIC program allows the rapid entry of DNA nucleotide sequences into personal computers. 
  • A simple enzyme-linked immunosorbent assay for antibodies to native DNA. 
  • A single AT-GC exchange can modulate charge transfer-induced p53-DNA dissociation. 
  • A single molecule detection method for understanding mechanisms of electric field-mediated interstitial transport of genes. 
  • A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC). 
  • A subgroup of murine monoclonal anti-deoxyribonucleic acid antibodies traverse the cytoplasm and enter the nucleus in a time-and temperature- dependent manner. 
  • A tale of tails: how histone tails mediate chromatin compaction in different salt and linker histone environments. 
  • A three-dimensional ParF meshwork assembles through the nucleoid to mediate plasmid segregation. 
  • A transcription factor affinity-based code for mammalian transcription initiation. 
  • A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation. 
  • A two-state DNA lattice switched by DNA nanoactuator. 
  • A unidirectional DNA walker that moves autonomously along a track. 
  • A yeast artificial chromosome contig encompassing the type 1 neurofibromatosis gene. 
  • ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. 
  • ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background. 
  • Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila. 
  • Absence of a simple code: how transcription factors read the genome. 
  • Absence of mutation in the beta-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's disease. 
  • Accuracy of BRCA1 and BRCA2 founder mutation analysis in formalin-fixed and paraffin-embedded (FFPE) tissue. 
  • Acetaminophen toxicity in cultured trout liver cells. I. Morphological alterations and effects on cytochrome P450 1A1. 
  • Activation of human B cells by phosphorothioate oligodeoxynucleotides. 
  • Activation of mitogen-activated protein kinase by epidermal growth factor in hippocampal neurons and neuronal cell lines. 
  • Activation of the Saccharomyces cerevisiae heat shock transcription factor under glucose starvation conditions by Snf1 protein kinase. 
  • Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. 
  • Active scaffolds for on-demand drug and cell delivery. 
  • Activin expression by cultured human retinal pigment epithelial cells. 
  • Activity of psoralen-functionalized nanoscintillators against cancer cells upon X-ray excitation. 
  • Acute tubular necrosis. An experimental model detailing the biochemical events accompanying renal injury and recovery. 
  • Adenosine 3',5'-monophosphate: a modulator of embryonic chick cartilage growth. 
  • Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements. 
  • Admission cell free DNA levels predict 28-day mortality in patients with severe sepsis in intensive care. 
  • Adrenergic modulation of cardiac development in the rat: effects of prenatal exposure to propranolol via continuous maternal infusion. 
  • Adsorption capacity of multiple DNA sources to clay minerals and environmental soil matrices less than previously estimated. 
  • Advances in the determination of nucleic acid conformational ensembles. 
  • Afforestation alters the composition of functional genes in soil and biogeochemical processes in South American grasslands. 
  • Age at maturity in wild baboons: genetic, environmental and demographic influences. 
  • Age distribution of latent herpes simplex virus 1 and varicella-zoster virus genome in human nervous tissue. 
  • Age-related changes of the 3'APOB-VNTR genotype pool in ageing cohorts. 
  • Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. 
  • All-trans-retinoic acid mediates G1 arrest but not apoptosis of normal human mammary epithelial cells. 
  • Allelic and locus heterogeneity in autosomal recessive gelatinous drop-like corneal dystrophy. 
  • Allogeneic microchimerism and donor antigen-specific hyporeactivity in lung transplant recipients. 
  • Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library. 
  • Alpers' syndrome presenting with seizures and multiple stroke-like episodes in a 17-year-old male. 
  • Alpha 1-adrenergic effects and liver regeneration. 
  • Alpha 2-macroglobulin binds CpG oligodeoxynucleotides and enhances their immunostimulatory properties by a receptor-dependent mechanism. 
  • Alteration of NF-kappa B p50 DNA binding kinetics by S-nitrosylation. 
  • Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing. 
  • Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism. 
  • Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells. 
  • Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors. 
  • Amino acid-level signal-to-noise analysis of incidentally identified variants in genes associated with long QT syndrome during pediatric whole exome sequencing reflects background genetic noise. 
  • Amplified on-chip fluorescence detection of DNA hybridization by surface-initiated enzymatic polymerization. 
  • Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes. 
  • An 18-locus linkage map of the pericentromeric region of the human X chromosome: genetic framework for mapping X-linked disorders. 
  • An HLA class II region restriction fragment length polymorphism (RFLP) in patients with dermatitis herpetiformis: association with HLA-DP phenotype. 
  • An autonomously self-assembling dendritic DNA nanostructure for target DNA detection. 
  • An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. 
  • An examination of the monophyly of morning glory taxa using Bayesian phylogenetic inference. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau. 
  • An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent. 
  • Analog Computation by DNA Strand Displacement Circuits. 
  • Analogs of tetrahydroisoquinoline natural products that inhibit cell migration and target galectin-3 outside of its carbohydrate-binding site. 
  • Analysis of Drosophila melanogaster satellite IV with restriction endonuclease MboII. 
  • Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins. 
  • Analysis of cleavage complexes using reactive inhibitor derivatives. 
  • Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. 
  • Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. 
  • Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro. 
  • Analysis of the Stargardt disease gene (ABCR) in age-related macular degeneration. 
  • Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspective. 
  • Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila. 
  • Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB. 
  • Analytical DNA fingerprinting in lions: parentage, genetic diversity, and kinship. 
  • Analytical Debye-Huckel model for electrostatic potentials around dissolved DNA. 
  • Analyzing cell cycle checkpoints after ionizing radiation. 
  • Ancient DNA from Megaladapis edwardsi. 
  • Ancient DNA from giant extinct lemurs confirms single origin of Malagasy primates. 
  • Ancient single origin for Malagasy primates. 
  • Androgen receptor gene alterations are not associated with isolated cryptorchidism. 
  • Anti-DNA and autoantibodies. 
  • Anti-DNA antibodies exhibit different binding motif preferences for single stranded or double stranded DNA. 
  • Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. 
  • Anti-DNA antibodies in systemic lupus erythematosus. 
  • Anti-DNA antibodies in systemic lupus erythematosus: a case of mistaken identity? 
  • Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats. 
  • Antibodies to DNA. A perspective. 
  • Antibodies to DNA: infection or genetics? 
  • Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. 
  • Antibody responses to DNA in normal immunity and aberrant immunity. 
  • Antimitotic and cytotoxic effects of theophylline in MDA-MB-231 human breast cancer cells. 
  • Antitumor agents--CLI. Bis(helenalinyl)glutarate and bis(isoalantodiol-B)glutarate, potent inhibitors of human DNA topoisomerase II. 
  • ApoE genotype and survival from intracerebral haemorrhage. 
  • Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition. 
  • Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase. 
  • Apoptosis in human retinal degenerations. 
  • Apoptosis in the cervix of pregnant rats in association with cervical softening. 
  • Apoptosis is the mode of cell death caused by carcinogenic chromium. 
  • Apoptosis leads to photoreceptor degeneration in inherited retinal dystrophy of RCS rats. 
  • Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. 
  • Application of proteomic marker ensembles to subcellular organelle identification. 
  • Application of random peptide phage display to the study of nuclear hormone receptors. 
  • Arabidopsis SNI1 and RAD51D regulate both gene transcription and DNA recombination during the defense response. 
  • Architecture of the human regulatory network derived from ENCODE data. 
  • Arithmetic difficulties in females with the fragile X premutation. 
  • Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. 
  • Articular chondrocyte tenascin-C production and assembly into de novo extracellular matrix. 
  • Ascorbic acid accumulates in cartilage in vivo. 
  • Ascorbic acid specifically increases type I and type III procollagen messenger RNA levels in human skin fibroblast. 
  • Assay variation in the detection of antinuclear antibodies in the sera of patients with established SLE. 
  • Assembly and molecular activities of the MutS tetramer. 
  • Assembly of alternating polycation and DNA multilayer films by electrostatic layer-by-layer adsorption. 
  • Assessing transcription factor motif drift from noisy decoy sequences. 
  • Assignment of human gamma crystallin multigene family to chromosome 2. 
  • Assignment of the gene for myelin proteolipid protein to the X chromosome: implications for X-linked myelin disorders. 
  • Assignment of the human glycogen debrancher gene to chromosome 1p21. 
  • Assignment of the human slow skeletal troponin T gene to 19q13.4 using somatic cell hybrids and fluorescence in situ hybridization analysis. 
  • Association between the V109G polymorphism of the p27 gene and the risk and progression of oral squamous cell carcinoma. 
  • Association of TP53 mutational status and gender with survival after adjuvant treatment for stage III colon cancer: results of CALGB 89803. 
  • Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. 
  • Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study. 
  • Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery. 
  • Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender. 
  • Association of the viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids. 
  • Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. 
  • Astatine-211-labeled radiotherapeutics: an emerging approach to targeted alpha-particle radiotherapy. 
  • Atomic structures of excited state A-T Hoogsteen base pairs in duplex DNA by combining NMR relaxation dispersion, mutagenesis, and chemical shift calculations. 
  • Atrial natriuretic polypeptide as a novel antigrowth factor of endothelial cells. 
  • Atypical features of familial hemophagocytic lymphohistiocytosis. 
  • Autoantibodies and their idiotypes. 
  • Autocrine and paracrine effects of atrial natriuretic peptide gene transfer on vascular smooth muscle and endothelial cellular growth. 
  • Autofeedback suppression of growth hormone (GH) secretion in transgenic mice expressing a human GH reporter targeted by tyrosine hydroxylase 5'-flanking sequences to the hypothalamus. 
  • Autoimmunity: the nuclear arsenal of autoimmunity. 
  • Automated constraint-based nucleotide sequence selection for DNA computation. 
  • Autosomal-dominant distal myopathy associated with a recurrent missense mutation in the gene encoding the nuclear matrix protein, matrin 3. 
  • Autosomal-dominant retinitis pigmentosa associated with an Arg-135-Trp point mutation of the rhodopsin gene. Clinical features and longitudinal observations. 
  • BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions. 
  • BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. 
  • Bacterial artificial chromosome cloning and mapping of a 630-kb human extrachromosomal structure. 
  • Bacterial expression and characterization of proteins derived from the chicken calmodulin cDNA and a calmodulin processed gene. 
  • Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair and the regulation of DNA replication origins. 
  • Barriers to productive transfection of trabecular meshwork cells. 
  • Basal and thyroid hormone receptor auxiliary protein-enhanced binding of thyroid hormone receptor isoforms to native thyroid hormone response elements. 
  • Basal forebrain moderates the magnitude of task-dependent amygdala functional connectivity. 
  • Base stacking and molecular polarizability: effect of a methyl group in the 5-position of pyrimidines. 
  • Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons. 
  • Base-specific arrest of in vitro DNA replication by carcinogenic chromium: relationship to DNA interstrand crosslinking. 
  • Bayesian analysis of mutational spectra. 
  • Bayesian hierarchically weighted finite mixture models for samples of distributions. 
  • Bcl-2 accelerates multistep prostate carcinogenesis in vivo. 
  • Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development. 
  • Beta satellite DNA: characterization and localization of two subfamilies from the distal and proximal short arms of the human acrocentric chromosomes. 
  • Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization. 
  • Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. 
  • Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions. 
  • Binding specificity of a monoclonal anti-DNA antibody. 
  • Biochemical and molecular homogeneity in the patellar tendon of the immature pig. 
  • Biochemical determinants of growth sparing during neonatal nutritional deprivation or enhancement: ornithine decarboxylase, polyamines, and macromolecules in brain regions and heart. 
  • Biochemical development of the rat lung: studies on cellular DNA, RNA and protein content in relation to maternal vitamin A status. 
  • Biochemical mass spectrometry: worth the weight? 
  • Biochemistry. Scaling up DNA computation. 
  • Biomaterial-mediated retroviral gene transfer using self-assembled monolayers. 
  • Biophysics of knotting. 
  • Bisulfite induces tandem double CC-->TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination. 
  • Blood-sample processing for the study of age-dependent gene expression in peripheral blood mononuclear cells. 
  • Bombesin increases fetal lung growth and maturation in utero and in organ culture. 
  • Boranophosphate nucleic acids--a versatile DNA backbone. 
  • Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort. 
  • Brave New World of human-rights DNA collection. 
  • Bromodeoxyuridine induction of deoxycytidine deaminase activity in a hamster cell line. 
  • Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells. 
  • C3orf58, a novel paracrine protein, stimulates cardiomyocyte cell-cycle progression through the PI3K-AKT-CDK7 pathway. 
  • CCAAT/enhancer-binding protein alpha is required for transcription of the beta 3-adrenergic receptor gene during adipogenesis. 
  • CD10/neutral endopeptidase 24.11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin-like peptides. 
  • COL5A1: fine genetic mapping and exclusion as candidate gene in families with nail-patella syndrome, tuberous sclerosis 1, hereditary hemorrhagic telangiectasia, and Ehlers-Danlos Syndrome type II. 
  • COOH-terminal requirements for the correct processing of a phosphatidylinositol-glycan anchored membrane protein. 
  • CRISPR-based methods for high-throughput annotation of regulatory DNA. 
  • Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms. 
  • Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. 
  • Caenorhabditis elegans as an emerging model system in environmental epigenetics. 
  • Caenorhabditis elegans cog-1 locus encodes GTX/Nkx6.1 homeodomain proteins and regulates multiple aspects of reproductive system development. 
  • Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo. 
  • Calcineurin regulates cyclin D1 accumulation in growth-stimulated fibroblasts. 
  • Calcium, calmodulin and cell proliferation. 
  • Calmodulin as a mediator of hormone action and cell regulation. 
  • Calspermin is a testis specific calmodulin-binding protein closely related to Ca2+/calmodulin-dependent protein kinases. 
  • Candidate gene analysis of 21q22: support for S100B as a susceptibility gene for bipolar affective disorder with psychosis. 
  • Canine model and genomic structural organization of glycogen storage disease type Ia (GSD Ia). 
  • Carbon nanotubes: measuring dispersion and length. 
  • Carcinogen induced unscheduled DNA synthesis in mouse hepatocytes. 
  • Cardiopulmonary Bypass Decreases Activation of the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway in Diabetic Human Myocardium. 
  • Cas9 loosens its grip on off-target sites. 
  • Cataract formation in a strain of rats selected for high oxidative stress. 
  • Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. 
  • Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. 
  • Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds. 
  • Cell cycle analysis of budding yeast using SYTOX Green. 
  • Cell division, growth and death. Cell growth: live and let die. 
  • Cell type-specific angiotensin II-evoked signal transduction pathways: critical roles of Gbetagamma subunit, Src family, and Ras in cardiac fibroblasts. 
  • Cell-Free DNA Screening: Complexities and Challenges of Clinical Implementation. 
  • Cell-free DNA analysis for noninvasive examination of trisomy. 
  • Cellular events during sexual development from amoeba to plasmodium in the slime mould Physarum polycephalum. 
  • Cellular mechanisms of cyclophosphamide resistance: model studies in human medulloblastoma cell lines. 
  • Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA. 
  • Characteristics associated with participation in DNA banking: The National Registry of Veterans with ALS. 
  • Characteristics of intergenerational contractions of the CTG repeat in myotonic dystrophy. 
  • Characteristics of macrophages obtained by bronchial lavage in humans. 
  • Characterization and expression of the complementary DNA encoding rat histidine decarboxylase. 
  • Characterization and property of DNA incorporated bilayer lipid membranes. 
  • Characterization and structure of the manganese-responsive transcriptional regulator ScaR. 
  • Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors. 
  • Characterization of DNA lesions induced by CaCrO4 in synchronous and asynchronous cultured mammalian cells. 
  • Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21. 
  • Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes. 
  • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. 
  • Characterization of a partial cDNA for lysyl hydroxylase from human skin fibroblasts; lysyl hydroxylase mRNAs are regulated differently by minoxidil derivatives and hydralazine. 
  • Characterization of a putative insulin-responsive element and its binding protein(s) in rat angiotensinogen gene promoter: regulation by glucose and insulin. 
  • Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy. 
  • Characterization of alpha 2-macroglobulin binding to human trabecular meshwork cells: presence of the alpha 2-macroglobulin signaling receptor. 
  • Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli. 
  • Characterization of cDNAs encoding the polypyrimidine tract-binding protein. 
  • Characterization of de novo duplications in eight patients by using fluorescence in situ hybridization with chromosome-specific DNA libraries. 
  • Characterization of human brain cDNA encoding the general isoform of beta-spectrin. 
  • Characterization of human prorenin expressed in mammalian cells from cloned cDNA. 
  • Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L. 
  • Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene. 
  • Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels. 
  • Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. 
  • Characterization of the statin-like S1 and rat elongation factor 1 alpha as two distinctly expressed messages in rat. 
  • Characterization of the tissue regression process in the uterus of older mice as apoptotic by the presence of Tp30, an isoform of terminin. 
  • Characterization of two types of yeast ribosomal DNA genes. 
  • Characterizing the protonation state of cytosine in transient G·C Hoogsteen base pairs in duplex DNA. 
  • Charge Transport across DNA-Based Three-Way Junctions. 
  • Charge splitters and charge transport junctions based on guanine quadruplexes. 
  • Charge-reversal amphiphiles for gene delivery. 
  • Charge-reversal lipids, peptide-based lipids, and nucleoside-based lipids for gene delivery. 
  • Chemical evidence for early but unsustained growth in the obstructed mouse kidney. 
  • Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides. 
  • Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas. 
  • Chicken calmodulin genes. A species comparison of cDNA sequences and isolation of a genomic clone. 
  • Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. 
  • Chiral control of electron transmission through molecules. 
  • Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. 
  • Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery. 
  • Chlorpyrifos exposure during neurulation: cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood. 
  • Cholera toxin and cell growth: role of membrane gangliosides. 
  • Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture. 
  • Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix. 
  • Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix. 
  • Chromatin perturbations during the DNA damage response in higher eukaryotes. 
  • Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signaling. 
  • Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle. 
  • Chromium-induced genotoxicity and apoptosis: relationship to chromium carcinogenesis (review). 
  • Chromosomal localization of human glutamate receptor genes. 
  • Chromosomal localization of the mouse Src-like adapter protein (Slap) gene and its putative human homolog SLA. 
  • Chromosomal localization of two genes underlying late-infantile neuronal ceroid lipofuscinosis. 
  • Chromosomal location of human P-glycoprotein gene sequences. 
  • Chromosomal organization of adrenergic receptor genes. 
  • Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript. 
  • Clinical and functional findings in choroideremia due to complete deletion of the CHM gene. 
  • Clinical heterogeneity in lymphoedema-distichiasis with FOXC2 truncating mutations. 
  • Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients. 
  • Clinical pharmacology of melphalan and its implications for clinical resistance to anticancer agents. 
  • Cloning and characterization of rat-brain-specific transcripts: rare, brain-specific transcripts and tyrosine hydroxylase. 
  • Cloning and characterization of the rat alpha 1a-adrenergic receptor gene promoter. Demonstration of cell specificity and regulation by hypoxia. 
  • Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. 
  • Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters. 
  • Cloning and expression of full-length cDNA encoding human vitamin D receptor. 
  • Cloning and functional characterization of a cocaine-sensitive dopamine transporter. 
  • Cloning and molecular characterization of a cDNA clone to statin, a protein specifically expressed in nonproliferating quiescent and senescent fibroblasts. 
  • Cloning of DNA corresponding to rare transcripts of rat brain: evidence of transcriptional and post-transcriptional control and of the existence of nonpolyadenylated transcripts. 
  • Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19. 
  • Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors. 
  • Cloning of the cDNA for the human beta 1-adrenergic receptor. 
  • Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. 
  • Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family. 
  • Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family. 
  • Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase. 
  • Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. 
  • Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells. 
  • Coarse-Grained Theory of Biological Charge Transfer with Spatially and Temporally Correlated Noise. 
  • Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions. 
  • Cocrystal structure of an editing complex of Klenow fragment with DNA. 
  • Cocultures of adult and juvenile chondrocytes compared with adult and juvenile chondral fragments: in vitro matrix production. 
  • Collagenase and connective tissue metabolism in epidermolysis bullosa. 
  • Combinatorial mutagenesis of the reactive site region in plasminogen activator inhibitor I. 
  • Commitment to cell death is signaled by the appearance of a terminin protein of 30 kDa. 
  • Comparative and population mitogenomic analyses of Madagascar's extinct, giant 'subfossil' lemurs. 
  • Comparative incorporation of P32 into lung phosphatidyl choline in mammals with different metabolic and pulmonary morphologic characteristics. 
  • Comparative metabolism and excretion of benzo(a)pyrene in 2 species of ictalurid catfish. 
  • Comparative studies on the secondary structure of ovalbumin messenger RNA and its complementary DNA transcript. 
  • Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models. 
  • Comparison of human and Xenopus GATA-2 promoters. 
  • Comparison of pulmonary and pleural responses of rats and hamsters to inhaled refractory ceramic fibers. 
  • Compensatory renal growth after unilateral ureteral obstruction. 
  • Complete deletion of the androgen receptor gene: definition of the null phenotype of the androgen insensitivity syndrome and determination of carrier status. 
  • Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. 
  • Complete genomic screen in late-onset familial Alzheimer's disease. 
  • Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5' untranslated sequence. 
  • Complex relationship between Parkin mutations and Parkinson disease. 
  • Complexity reduction in context-dependent DNA substitution models. 
  • Composition and transport properties of human ankle and knee cartilage. 
  • Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes. 
  • Computing. Successes and challenges. 
  • Confirmation of a second locus for CMT2 and evidence for additional genetic heterogeneity. 
  • Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. 
  • Conformational Dynamics of Mechanically Compliant DNA Nanostructures from Coarse-Grained Molecular Dynamics Simulations. 
  • Conformational transition of DNA induced by cationic lipid vesicle in acidic solution: spectroscopy investigation. 
  • Conformationally Gated Charge Transfer in DNA Three-Way Junctions. 
  • Connecting the nanodots: programmable nanofabrication of fused metal shapes on DNA templates. 
  • Consent process for US-based family reference DNA samples. 
  • Consistent production of transgenic chickens using replication-deficient retroviral vectors and high-throughput screening procedures. 
  • Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation. 
  • Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival. 
  • Construction and control of plasmid DNA network. 
  • Contractile proteins in Drosophila development. 
  • Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. 
  • Control of phenylalanine hydroxylase synthesis in tissue culture by serum and insulin. 
  • Controlled gene delivery by DNA-gelatin nanospheres. 
  • Coordinate reduction of rat pancreatic islet glucokinase and proinsulin mRNA by exercise training. 
  • Coordination of DNA ends during double-strand-break repair in bacteriophage T4. 
  • Copper-binding motifs in catalysis, transport, detoxification and signaling. 
  • Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency. 
  • Correlation of UVC and UVB cytotoxicity with the induction of specific photoproducts in T-lymphocytes and fibroblasts from normal human donors. 
  • Correlation of total and interstrand DNA adducts in tumor and kidney with antitumor efficacies and differential nephrotoxicities of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin. 
  • Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system. 
  • Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man. 
  • Critical role of chromium (Cr)-DNA interactions in the formation of Cr-induced polymerase arresting lesions. 
  • Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. 
  • Crossover interference on nucleolus organizing region-bearing chromosomes in Arabidopsis. 
  • Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. 
  • Crystal structure of MtaN, a global multidrug transporter gene activator. 
  • Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. 
  • Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity. 
  • Crystal structure of the transcription activator BmrR bound to DNA and a drug. 
  • Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells. 
  • Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis. 
  • Cultivation of murine hair follicles as organoids in a collagen matrix. 
  • Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. 
  • Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin. 
  • Cyclic AMP mediated GSTP1 gene activation in tumor cells involves the interaction of activated CREB-1 with the GSTP1 CRE: a novel mechanism of cellular GSTP1 gene regulation. 
  • Cyclin D/CDK4/6 activity controls G1 length in mammalian cells. 
  • Cytochrome P1-450 structural gene in mouse, rat, and rabbit: differences in DNA methylation and developmental expression of mRNA. 
  • Cytokine production at the site of disease in human tuberculosis. 
  • Cytokinetic and molecular pharmacology studies of arabinosylcytosine in metastatic melanoma. 
  • Cytological evidence for DNA chain elongation after UV irradiation in the S phase. 
  • Cytological evidence of transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. 
  • D2 dopamine receptors in the human retina: cloning of cDNA and localization of mRNA. 
  • DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin. 
  • DNA adducts and exposure to burning oil. 
  • DNA and immunoglobulin synthesis by rabbit peripheral blood lymphocytes in vitro: complete and incomplete stimulation. 
  • DNA as a marker of cell death in systemic lupus erythematosus. 
  • DNA base modification: ionized base pairs and mutagenesis. 
  • DNA binding by the Myc oncoproteins. 
  • DNA binds and activates complement via residues 14-26 of the human C1q A chain. 
  • DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes. 
  • DNA conformation, topology, and the regulation of c-myc expression. 
  • DNA copy number evolution in Drosophila cell lines. 
  • DNA damage induces phosphorylation of the amino terminus of p53. 
  • DNA delivery from matrix metalloproteinase degradable poly(ethylene glycol) hydrogels to mouse cloned mesenchymal stem cells. 
  • DNA methyltransferase levels and altered CpG methylation in the total genome and in the GSTP1 gene in human glioma cells transfected with sense and antisense DNA methyltransferase cDNA. 
  • DNA mismatch repair: functions and mechanisms. 
  • DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires. 
  • DNA network structures on various solid substrates investigated by atomic force microscopy. 
  • DNA patents and diagnostics: not a pretty picture. 
  • DNA polymerase arrest by adducted trivalent chromium. 
  • DNA polymerase delta is required for human mismatch repair in vitro. 
  • DNA repair in human leukaemic lymphocytes. 
  • DNA repair synthesis in isolated rainbow trout liver cells. 
  • DNA replication and progression through the cell cycle. 
  • DNA robots sort as they walk. 
  • DNA sequence analysis and restriction fragment length polymorphism (RFLP) typing of the HLA-DQw2 alleles associated with dermatitis herpetiformis. 
  • DNA strand breakage by wheat germ type 1 topoisomerase. 
  • DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. 
  • DNA surveillance: web-based molecular identification of whales, dolphins, and porpoises. 
  • DNA synthesis, assembly and applications in synthetic biology. 
  • DNA topoisomerases. 
  • DNA typing for HLA-A and HLA-B identifies disparities between patients and unrelated donors matched by HLA-A and HLA-B serology and HLA-DRB1. 
  • DNA vaccination. A clue to memory? 
  • DNA-Based Analog Computing. 
  • DNA-based animal models of human disease: from genotype to phenotype. 
  • DNA-binding agents. 
  • DNA-dependent activation of the hMutSalpha ATPase. 
  • DNA-enabled integrated molecular systems for computation and sensing. 
  • DNA-polycation nanospheres as non-viral gene delivery vehicles. 
  • DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells. 
  • DNA-templated self-assembly of protein and nanoparticle linear arrays. 
  • DNA-templated self-assembly of protein arrays and highly conductive nanowires. 
  • DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). 
  • DNA: Insulator or wire? 
  • DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types. 
  • DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells. 
  • Dating branches on the tree of life using DNA. 
  • De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence. 
  • Decellularized native and engineered arterial scaffolds for transplantation. 
  • Decreased cochlear DNA receptor staining in MRL.MpJ-Fas(lpr) autoimmune mice with hearing loss. 
  • Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. 
  • Defects in mononuclear phagocytic system (MPS) function in autoimmune MRL-lpr/lpr mice. 
  • Defending information-free genocentrism. 
  • Defining functional DNA elements in the human genome. 
  • Definition of the cellular mechanisms which distinguish between hormone and antihormone activated steroid receptors. 
  • Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation. 
  • Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. 
  • Delimiting species without nuclear monophyly in Madagascar's mouse lemurs. 
  • Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. 
  • Deoxyribonucleic acid ligase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from Escherichia coli. 
  • Deoxyribonucleic acid ligase. Isolation and physical characterization of the homogeneous enzyme from Escherichia coli. 
  • Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1. 
  • Design and Analysis of Compact DNA Strand Displacement Circuits for Analog Computation Using Autocatalytic Amplifiers. 
  • Design and Analysis of Localized DNA Hybridization Chain Reactions. 
  • Design and characterization of microporous hyaluronic acid hydrogels for in vitro gene transfer to mMSCs. 
  • Design and construction of double-decker tile as a route to three-dimensional periodic assembly of DNA. 
  • Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). 
  • Detecting colorectal cancer in stool with the use of multiple genetic targets. 
  • Detecting solvent-driven transitions of poly(A) to double-stranded conformations by atomic force microscopy. 
  • Detecting ultraviolet damage in single DNA molecules by atomic force microscopy. 
  • Detection of mutations by cleavage of DNA heteroduplexes with bacteriophage resolvases. 
  • Detection of proximal colorectal cancers through analysis of faecal DNA. 
  • Determinants of deoxyadenosine toxicity in hybrids between human T- and B- lymphoblasts as a model for the development of drug resistance in T-cell acute lymphoblastic leukemia. 
  • Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers. 
  • Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. 
  • Development of autoantibodies before the clinical onset of systemic lupus erythematosus. 
  • Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1. 
  • Developmental cholinotoxicants: nicotine and chlorpyrifos. 
  • Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio). 
  • Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation. 
  • Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. 
  • Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. 
  • Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration. 
  • Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period? 
  • Developmental pattern of DNA and proteins in brain, liver, lung and heart of rats given excess vitamin A postnatally. 
  • Developmental pattern of the hepatic DNA, RNA and protein in relation to maternal vitamin A status in rats. 
  • Developmental toxicity of terbutaline: critical periods for sex-selective effects on macromolecules and DNA synthesis in rat brain, heart, and liver. 
  • Diagnosis of mitochondrial trifunctional protein deficiency in a blood spot from the newborn screening card by tandem mass spectrometry and DNA analysis. 
  • Diagnostic accuracy of noninvasive fetal Rh genotyping from maternal blood--a meta-analysis. 
  • Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex. 
  • Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis. 
  • Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia. 
  • Different dimerization activities of alpha and beta thyroid hormone receptor isoforms. 
  • Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression. 
  • Differential binding of c-Myc and Max to nucleosomal DNA. 
  • Differential effect of secondary aqueous humor from rabbit and cat on DNA synthesis of cultured bovine corneal endothelial cells. 
  • Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans. 
  • Differential expression of guanine nucleotide-binding proteins enhances cAMP synthesis in regenerating rat liver. 
  • Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes. 
  • Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. 
  • Differential molecular mechanism of the estrogen action that regulates lactoferrin gene in human and mouse. 
  • Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo. 
  • Differential replication of satellite DNA in polyploid tissues of Drosophila virilis. 
  • Differential sensitivity of chromium-mediated DNA interstrand crosslinks and DNA-protein crosslinks to disruption by alkali and EDTA. 
  • Differential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sites. 
  • Differential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces. 
  • Differentially labeled mutant oligonucleotides for analysis of protein-DNA interactions. 
  • Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents. 
  • Dinucleotide repeat polymorphism at the human erythropoietin receptor locus (EPOR) at 19p13. 
  • Dioxinlike properties of a trichloroethylene combustion-generated aerosol. 
  • Direct MHC class I complementary DNA transfer to thymus induces donor-specific unresponsiveness, which involves multiple immunologic mechanisms. 
  • Direct NMR Evidence that Transient Tautomeric and Anionic States in dG·dT Form Watson-Crick-like Base Pairs. 
  • Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2. 
  • Direct measurements of base stacking interactions in DNA by single-molecule atomic-force spectroscopy. 
  • Directed enzymatic activation of 1-D DNA tiles. 
  • Directed nucleation assembly of DNA tile complexes for barcode-patterned lattices. 
  • Disappearance of statin, a protein marker for non-proliferating and senescent cells, following serum-stimulated cell cycle entry. 
  • Discerning the ancestry of European Americans in genetic association studies. 
  • Discovering sequences with potential regulatory characteristics. 
  • Discovery of protein- and DNA-imperceptible nanoparticle hard coating using gel-based reaction tuning. 
  • Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis. 
  • Disruption of rat forebrain development by glucocorticoids: critical perinatal periods for effects on neural cell acquisition and on cell signaling cascades mediating noradrenergic and cholinergic neurotransmitter/neurotrophic responses. 
  • Dissecting the differences between the alpha and beta anomers of the oxidative DNA lesion FaPydG. 
  • Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins. 
  • Dissociation of bacteriophage T4 DNA polymerase and its processivity clamp after completion of Okazaki fragment synthesis. 
  • Dissociation of thymidine incorporation and transferrin receptor expression from cell growth and c-myc accumulation in alpha-interferon-treated cells. 
  • Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis. 
  • Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. 
  • Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression. 
  • Distinctive subtypes of bovine phospholipase C that have preferential expression in the retina and high homology to the norpA gene product of Drosophila. 
  • Distribution of 5-methyldeoxycytidine in products of staphylococcal nuclease digestion of nuclei and purified DNA. 
  • Distribution of repair-incorporated nucleotides and nucleosome rearrangement in the chromatin of normal and xeroderma pigmentosum human fibroblasts. 
  • Divergence between the Drosophila pseudoobscura and D. persimilis genome sequences in relation to chromosomal inversions. 
  • Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins. 
  • Does concurrent or prior nicotine exposure interact with neonatal hypoxia to produce cardiac cell damage? 
  • Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats. 
  • Does prenatal nicotine exposure sensitize the brain to nicotine-induced neurotoxicity in adolescence? 
  • Does the aging skeletal muscle maintain its endocrine function? 
  • Domain organization of chicken gizzard myosin light chain kinase deduced from a cloned cDNA. 
  • Domain structure and DNA binding regions of beta protein from bacteriophage lambda. 
  • Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. 
  • Donor-bridge-acceptor energetics determine the distance dependence of electron tunneling in DNA. 
  • Double-strand breaks associated with repetitive DNA can reshape the genome. 
  • Down-regulation of transforming growth factor beta receptor type I, II, and III during liver regeneration. 
  • Drosophila follicle cell amplicons as models for metazoan DNA replication: a cyclinE mutant exhibits increased replication fork elongation. 
  • Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins. 
  • Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency. 
  • Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry. 
  • Duration of nuclear NF-kappaB action regulated by reversible acetylation. 
  • Dynamic basis for dG•dT misincorporation via tautomerization and ionization. 
  • Dynamical treatment of charge transfer through duplex nucleic acids containing modified adenines. 
  • Dynamics of Forced Nucleosome Unraveling and Role of Nonuniform Histone-DNA Interactions 
  • Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch. 
  • Early estrogen action: concomitant stimulations within two minutes of nuclear RNA synthesis and uptake of RNA precursor by the uterus. 
  • EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme. 
  • Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. 
  • Effect of DNA conformation on cisplatin adduct formation. 
  • Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice. 
  • Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin. 
  • Effect of cytofectins on the immune response of murine macrophages to mammalian DNA. 
  • Effect of epidermal growth factor on ornithine decarboxylase activity in A431 cells. 
  • Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. 
  • Effect of ethanol on polyamine synthesis during liver regeneration in rats. 
  • Effect of nickel(II) on DNA-protein binding, thymidine incorporation, and sedimentation pattern of chromatin fractions from intact mammalian cells. 
  • Effect of proximal transposition of the ileum on mucosal growth and enzyme activity in orally nourished rats. 
  • Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters. 
  • Effect of transient hydronephrosis on subsequent compensatory renal growth. 
  • Effect os xid on anti-DNA B-cell precursors. 
  • Effects of MK-801 on DNA synthesis in neonatal rat brain regions under normoxic and hypoxic conditions. 
  • Effects of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase, on nucleic acids and proteins in developing rat brain: critical perinatal periods for regional selectivity. 
  • Effects of ammonium ion derived from bovine endothelial cells upon low density lipoprotein degradation in cultured vascular smooth muscle cells. 
  • Effects of benzo[a]pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site. 
  • Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers. 
  • Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation. 
  • Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth. 
  • Effects of continuous diazepam administration on GABAA subunit mRNA in rat brain. 
  • Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR). 
  • Effects of environmental tobacco smoke exposure in utero and/or postnatally on brain development. 
  • Effects of glutathione on chromium-induced DNA crosslinking and DNA polymerase arrest. 
  • Effects of inversions on within- and between-species recombination and divergence. 
  • Effects of neonatal methylmercury exposure on development of nucleic acids and proteins in rat brain: regional specificity. 
  • Effects of nickel(II) on nuclear protein binding to DNA in intact mammalian cells. 
  • Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps. 
  • Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. 
  • Effects of prenatal terbutaline exposure on cellular development in lung and liver of neonatal rat: ornithine decarboxylase activity and macromolecules. 
  • Effects of pulse strength and pulse duration on in vitro DNA electromobility. 
  • Effects of rabbit platelets on vascular smooth muscle cell DNA synthesis. 
  • Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans. 
  • Effects of source of DNA on genotyping success rates and allele percentages in the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS). 
  • Effects of the Backbone and Chemical Linker on the Molecular Conductance of Nucleic Acid Duplexes. 
  • Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene. 
  • Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial. 
  • Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. 
  • Efficient random subcloning of DNA sheared in a recirculating point-sink flow system. 
  • Electric field of a six-needle array electrode used in drug and DNA delivery in vivo: analytical versus numerical solution. 
  • Electrical energy required to form large conducting pores. 
  • Electron transfer characteristics of 2'-deoxy-2'-fluoro-arabinonucleic acid, a nucleic acid with enhanced chemical stability. 
  • Electron transfer mechanisms. 
  • Elevation of cAMP is required for down-regulation, but not agonist-induced desensitization, of endogenous dopamine D1 receptors in opossum kidney cells. Studies in cells that stably express a rat cAMP phosphodiesterase (rPDE3) cDNA. 
  • Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates. 
  • Emergence of the keratinocyte growth factor multigene family during the great ape radiation. 
  • Encoded multichromophore response for simultaneous label-free detection. 
  • Endogenous polymers of ADP-ribose are associated with the nuclear matrix. 
  • Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. 
  • Endonuclease cleavage of blocked replication forks: An indirect pathway of DNA damage from antitumor drug-topoisomerase complexes. 
  • Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages. 
  • Endotoxin-mediated nitric oxide synthesis inhibits IL-1beta gene transcription in ANA-1 murine macrophages. 
  • Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. 
  • Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas. 
  • Engineering gene expression and protein synthesis by modulation of nuclear shape. 
  • Engineering life: building a fab for biology. 
  • Engineering nanometre-scale coherence in soft matter. 
  • Enhanced catalytic DNAzyme for label-free colorimetric detection of DNA. 
  • Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells. 
  • Enhanced gene expression in mouse muscle by sustained release of plasmid DNA using PPE-EA as a carrier. 
  • Enhanced gene expression of systemically administered plasmid DNA in the liver with therapeutic ultrasound and microbubbles. 
  • Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone. 
  • Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements. 
  • Enzymatic fabrication of DNA nanostructures: extension of a self-assembled oligonucleotide monolayer on gold arrays. 
  • Epigenetic detection of human chromosome 14 uniparental disomy. 
  • ErbB2 activity is required for airway epithelial repair following neutrophil elastase exposure. 
  • Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. 
  • Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution. 
  • Erythroid AP-1/NF-E2 elements vary in their response to NF-E2. 
  • Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. 
  • Essential amino acid deprivation induces monocytic differentiation of the human HL-60 myeloid leukemia cell line. 
  • Estrogen induction of ovalbumin mRNA: evidence for transcription control. 
  • Etanercept-induced lupus-like syndrome in a patient with rheumatoid arthritis. 
  • Ethanol promotes hydrolysis of 3H-labeled sialoconjugates from brain of mice in vitro. 
  • Ethiopian strains of Trypanosoma brucei subspecies. 
  • Eukaryotic gene transcription with purified components. 
  • Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET. 
  • Evaluation of hyperbranched poly(amino ester)s of amine constitutions similar to polyethylenimine for DNA delivery. 
  • Evaluation of the fiber-optic antibody-based fluoroimmunosensor for DNA adducts in human placenta samples. 
  • Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression. 
  • Evidence for coincident mutations in human lymphoblast clones selected for functional loss of a thymidine kinase gene. 
  • Evidence for direct local effect of angiotensin in vascular hypertrophy. In vivo gene transfer of angiotensin converting enzyme. 
  • Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins. 
  • Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. 
  • Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000. 
  • Evidence that methylation of the FMR-I locus is responsible for variable phenotypic expression of the fragile X syndrome. 
  • Evolution and sequence analysis of a human Y-chromosomal DNA fragment. 
  • Evolution of a complex eukaryotic gene. 
  • Evolution of calcium-carbonate skeletons in the Hydractiniidae. 
  • Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes. 
  • Evolutionary conservation of possible functional domains of the human and murine XIST genes. 
  • Evolutionary mechanisms for eucaryotic genes. 
  • Excision repair is required for genotoxin-induced mutagenesis in mammalian cells. 
  • Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons. 
  • Exclusion of maternal uniparental disomy of chromosome 14 in patients referred for Prader-Willi syndrome using a multiplex methylation polymerase chain reaction assay. 
  • Exome Sequence Analysis of 14 Families With High Myopia. 
  • Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth. 
  • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 
  • Exon skipping in purine nucleoside phosphorylase mRNA processing leading to severe immunodeficiency. 
  • Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine. 
  • Experimental determination of rates of concerted evolution. 
  • Exploring motif composition of eukaryotic promoter regions. 
  • Exponential distance statistics to detect the effects of population subdivision. 
  • Exposure of cultured murine peritoneal macrophages to low concentrations of beryllium induces increases in intracellular calcium concentrations and stimulates DNA synthesis. 
  • Exposure of mice to topical bovine thrombin induces systemic autoimmunity. 
  • Exposure to hyperoxia induces p53 expression in mouse lung epithelium. 
  • Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region. 
  • Expression and sequence analysis of a cDNA encoding the orotidine-5'-monophosphate decarboxylase domain from Ehrlich ascites uridylate synthase. 
  • Expression and subcellular distribution of mouse cytochrome P1-450 mRNA as determined by molecular hybridization with cloned P1-450 DNA. 
  • Expression cloning and characterization of the TGF-beta type III receptor. 
  • Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction. 
  • Expression of MXI1, a Myc antagonist, is regulated by Sp1 and AP2. 
  • Expression of O6-methylguanine-DNA methyltransferase in malignant human glioma cell lines. 
  • Expression of RNAs for calmodulin, actins, and tubulins in rat testis cells. 
  • Expression of a highly conserved anti-DNA idiotype in normal and autoimmune mice. 
  • Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors. 
  • Expression of active, membrane-bound human placental alkaline phosphatase by transfected simian cells. 
  • Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance. 
  • Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase. 
  • Expression of human protein phosphatase-1 in Saccharomyces cerevisiae highlights the role of phosphatase isoforms in regulating eukaryotic functions. 
  • Expression of human vitamin D receptor in Saccharomyces cerevisiae. Purification, properties, and generation of polyclonal antibodies. 
  • Expression of mRNAs in human thymus coding for the alpha 3 subunit of a neuronal acetylcholine receptor. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth. 
  • Expression of transcription factor E2F1 induces quiescent cells to enter S phase. 
  • Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection. 
  • Expression of unusually large keratins during terminal differentiation: balance of type I and type II keratins is not disrupted. 
  • Expression, purification and primary crystallographic study of human androgen receptor in complex with DNA and coactivator motifs. 
  • Extended passaging, but not aldehyde dehydrogenase activity, increases the chondrogenic potential of human adipose-derived adult stem cells. 
  • Extending assembly of short DNA sequences to handle error. 
  • Extending the range of microsecond-to-millisecond chemical exchange detected in labeled and unlabeled nucleic acids by selective carbon R(1rho) NMR spectroscopy. 
  • Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR. 
  • Extent of equilibrium perturbation of the DNA helix upon enzymatic methylation of adenine residues. 
  • Extracellular potassium influences DNA and protein syntheses and glial fibrillary acidic protein expression in cultured glial cells. 
  • FACS-optimized mutants of the green fluorescent protein (GFP). 
  • FGF12 is a candidate Brugada syndrome locus. 
  • Fabrication of layer-by-layer deposited multilayer films containing DNA and its interaction with methyl green. 
  • Facial pain with localized and widespread manifestations: separate pathways of vulnerability. 
  • Facilitated diffusion during catalysis by EcoRI endonuclease. Nonspecific interactions in EcoRI catalysis. 
  • Factors regulating islet regeneration in the post-insulinoma NEDH rat. 
  • Factors that enhance Escherichia coli-expressed TR beta binding to T3 and DNA. 
  • Failure of the ILD to determine data combinability for slow loris phylogeny. 
  • Familial X-linked myalgia and cramps: a nonprogressive myopathy associated with a deletion in the dystrophin gene. 
  • Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation. 
  • Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001. 
  • Female steroid hormones and target cell nuclei. 
  • Fetal dexamethasone exposure alters macromolecular characteristics of rat brain development: a critical period for regionally selective alterations? 
  • Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: effects on DNA and protein in whole tissues. 
  • Fetal dexamethasone exposure sensitizes neonatal rat brain to hypoxia: effects on protein and DNA synthesis. 
  • Fiber autoradiography of replicating yeast DNA. 
  • Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. 
  • Field distribution and DNA transport in solid tumors during electric field-mediated gene delivery. 
  • Field- and phage-induced dipolar couplings in a homodimeric DNA quadruplex: relative orientation of G.(C-A) triad and G-tetrad motifs and direct determination of C2 symmetry axis orientation. 
  • Fine mapping of a putative rd cDNA and its co-segregation with rd expression. 
  • Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. 
  • Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence. 
  • Finite-size, fully addressable DNA tile lattices formed by hierarchical assembly procedures. 
  • Flexible histone tails in a new mesoscopic oligonucleosome model. 
  • Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation. 
  • Flow cytometric analysis of DNA content in budding yeast. 
  • Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation. 
  • Flow linear dichroism and electron microscopic analysis of protein-DNA complexes of a mutant UvrB protein that binds to but cannot kink DNA. 
  • Flow perfusion maintains ex vivo bone viability: a novel model for bone biology research. 
  • Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region. 
  • Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery. 
  • Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. 
  • Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. 
  • Formation and repair of 1,3-bis-(2-chloroethyl)-1-nitrosourea and cisplatin induced total genomic DNA interstrand crosslinks in human glioma cells. 
  • Formulations which increase the size of lipoplexes prevent serum-associated inhibition of transfection. 
  • Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice. 
  • Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts. 
  • Fragments of ATM which have dominant-negative or complementing activity. 
  • From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms. 
  • From the Cover: mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events. 
  • Full-electron calculation of effective electronic couplings and excitation energies of charge transfer states: Application to hole transfer in DNA pi-stacks. 
  • Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes. 
  • Functional alterations of macrophages in autoimmune MRL-lpr/lpr mice. 
  • Functional analysis of a complementary DNA for the 50-kilodalton subunit of calmodulin kinase II. 
  • Functional association of the parkin gene promoter with idiopathic Parkinson's disease. 
  • Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. 
  • Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. 
  • Functional expression of a MAP kinase kinase in COS cells and recognition by an anti-STE7/byr1 antibody. 
  • Functional heterogeneity of mammalian TATA-box sequences revealed by interaction with a cell-specific enhancer. 
  • Functional high efficiency expression of cloned leukocyte chemoattractant receptor cDNAs. 
  • Functional nanostructures from surface chemistry patterning. 
  • Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. 
  • Functional specialization of beta-arrestin interactions revealed by proteomic analysis. 
  • Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo. 
  • G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions. 
  • GC sequence specific recognition by an N-formamido, C-terminus-modified and imidazole-containing analogue of netropsin. 
  • Gamma-radiation sensitivity and risk of glioma. 
  • Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide. 
  • Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. 
  • Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. 
  • Gene expression signatures that predict radiation exposure in mice and humans. 
  • Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis. 
  • Gene transfer and expression in rat cardiac transplants. 
  • Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles. 
  • Genetic Polymorphisms of CFH and ARMS2 Do Not Predict Response to Antioxidants and Zinc in Patients with Age-Related Macular Degeneration: Independent Statistical Evaluations of Data from the Age-Related Eye Disease Study. 
  • Genetic and hormonal sensitivity to threat: testing a serotonin transporter genotype × testosterone interaction. 
  • Genetic and mutational analyses of a large multiethnic Bardet-Biedl cohort reveal a minor involvement of BBS6 and delineate the critical intervals of other loci. 
  • Genetic and physical mapping around the properdin P gene. 
  • Genetic approaches for the investigation of genes associated with coronary heart disease. 
  • Genetic changes in human adrenocortical carcinomas. 
  • Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. 
  • Genetic diversity does not explain variation in extra-pair paternity in multiple populations of a songbird. 
  • Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. 
  • Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population. 
  • Genetic heterogeneity in MCAD deficiency: frequency of K329E allele and identification of three additional mutant alleles. 
  • Genetic linkage studies of chromosome 17 RFLPs in von Recklinghausen neurofibromatosis (NF1). 
  • Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1. 
  • Genetic mutations in African patients with atrial fibrillation: Rationale and design of the Study of Genetics of Atrial Fibrillation in an African Population (SIGNAL). 
  • Genetic selection for constitutively trimerized human HSF1 mutants identifies a role for coiled-coil motifs in DNA binding. 
  • Genetic studies in autistic disorder and chromosome 15. 
  • Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1. 
  • Genetic variants associated with severe retinopathy of prematurity in extremely low birth weight infants. 
  • Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis. 
  • Genetically engineered calmodulins differentially activate target enzymes. 
  • Genome organization and three kinds of heritable changes: general description and stochastic factors (a review). 
  • Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. 
  • Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions. 
  • Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery. 
  • Genome-wide association study of smoking behaviours in patients with COPD. 
  • Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. 
  • Genome-wide localization of replication factors. 
  • Genome-wide scan reveals signatures of selection related to pollution adaptation in non-model estuarine Atlantic killifish (Fundulus heteroclitus). 
  • Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators. 
  • Genomic amplification with transcript sequencing. 
  • Genomic and epigenetic evidence for oxytocin receptor deficiency in autism. 
  • Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex. 
  • Genomic heat shock element sequences drive cooperative human heat shock factor 1 DNA binding and selectivity. 
  • Genomic organization of human complement protein C8 alpha and further examination of its linkage to C8 beta. 
  • Genomic organization of rat rDNA. 
  • Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. 
  • Genomic structure and embryonic expression of estrogen receptor beta a (ERbetaa) in zebrafish (Danio rerio). 
  • Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice. 
  • Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution. 
  • Global pharmacogenetics: genetic substructure of Eurasian populations and its effect on variants of drug-metabolizing enzymes. 
  • Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein. 
  • Glucose metabolism gene variants modulate the risk of pancreatic cancer. 
  • Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4. 
  • Glutathione activates virulence gene expression of an intracellular pathogen. 
  • Group II introns designed to insert into therapeutically relevant DNA target sites in human cells. 
  • Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast. 
  • Guanine to inosine substitution leads to large increases in the population of a transient G·C Hoogsteen base pair. 
  • HL-A antigenic loss in malignant transformation. 
  • HLA-C disparity between patients and unrelated donors matched for HLA-A, -B, and -DRB1 alleles: impact of serological vs. DNA typing for HLA-A and -B loci. 
  • HMGB1 and microparticles as mediators of the immune response to cell death. 
  • Hacking DNA copy number for circuit engineering. 
  • Half-site arrangement of hybrid glucocorticoid and thyroid hormone response elements specifies thyroid hormone receptor complex binding to DNA and transcriptional activity. 
  • Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration. 
  • Heat-shock protein-70 genes and response to antidepressants in major depression. 
  • Hemoglobin sickle-Lepore: report of two siblings and review of the literature. 
  • Hepatic regeneration and metabolism after partial hepatectomy in diabetic rats: effects of insulin therapy. 
  • Hepatitis B core antibody positive donors as a safe and effective therapeutic option to increase available organs for lung transplantation. 
  • Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8. 
  • Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein. 
  • Heterodimerization and deoxyribonucleic acid-binding properties of a retinoid X receptor-related factor. 
  • High level expression of a truncated chicken progesterone receptor in Escherichia coli. 
  • High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot. 
  • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. 
  • High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies. 
  • Highly active zinc-finger nucleases by extended modular assembly. 
  • Histologic, nuclear DNA, and human papillomavirus studies of cervical condylomas. 
  • Histone H1 enhances the DNA binding activity of the transcription factor EmBP-1. 
  • Histones of rat testis chromatin during early postnatal development and their interactions with DNA. 
  • Hormonal control of oviduct growth and differentiation. 
  • Human IgE synthesis in vitro: a reassessment. 
  • Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct. 
  • Human PXR forms a tryptophan zipper-mediated homodimer. 
  • Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA. 
  • Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products. 
  • Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. 
  • Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. 
  • Human chromosomes with shorter telomeres and large heterochromatin regions have a higher frequency of acquired somatic cell aneuploidy. 
  • Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair. 
  • Human mismatch repair: reconstitution of a nick-directed bidirectional reaction. 
  • Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. 
  • Hyalocytes synthesize and secrete inhibitors of retinal pigment epithelial cell proliferation in vitro. 
  • Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery. 
  • Hybridization studies with a renin cDNA probe: evidence for widespread expression of renin in the mouse. 
  • Hybridoma SLE autoantibodies: insights for the pathogenesis of autoimmune disease. 
  • Hydrogel-nanoparticle composites for optically modulated cancer therapeutic delivery. 
  • Hydrolysis of N3-methyl-2'-deoxycytidine: model compound for reactivity of protonated cytosine residues in DNA. 
  • Hydrolysis of template and newly synthesized deoxyribonucleic acid by the 3' to 5' exonuclease activity of the T4 deoxyribonucleic acid polymerase. 
  • Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity. 
  • Hyperbranched poly(amino ester)s with different terminal amine groups for DNA delivery. 
  • Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. 
  • Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. 
  • Hypoxia impedes the formation of chromium DNA-adducts in a cell-free system. 
  • IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription. 
  • Identification and analysis of eukaryotic promoters: recent computational approaches. 
  • Identification and cell type specificity of the tyrosine hydroxylase gene promoter. 
  • Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450. 
  • Identification and quantification of a messenger ribonucleic acid induced by polynuclear aromatic hydrocarbons--using a cloned human cytochrome P-450 gene. 
  • Identification and sequence of the initiation site for rat 45S ribosomal RNA synthesis. 
  • Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing. 
  • Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor. 
  • Identification of a deletion in the adenosine deaminase gene in a child with severe combined immunodeficiency. 
  • Identification of a new mutation in medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. 
  • Identification of a nonsense mutation at codon 128 of the Norrie's disease gene in a male infant. 
  • Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2. 
  • Identification of a putative second T-cell receptor. 
  • Identification of a rat glomerular mesangial cell mitogenic 5-HT2A receptor. 
  • Identification of a third autonomous activation domain within the human estrogen receptor. 
  • Identification of an alternate promoter in the rat androgen-binding protein/sex hormone-binding globulin gene that regulates synthesis of a messenger RNA encoding a protein with altered function. 
  • Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. I. High resolution epitope mapping and characterization of monoclonal antibody binding sites. 
  • Identification of fungi associated with municipal compost using DNA-based techniques. 
  • Identification of liver cancer-specific aptamers using whole live cells. 
  • Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA. 
  • Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands. 
  • Identification of putative human T cell receptor delta complementary DNA clones. 
  • Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains. 
  • Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. 
  • Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets. 
  • Identification, characterization, and molecular cloning of a novel transporter-like protein localized to the central nervous system. 
  • Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1. 
  • Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. 
  • Identifying sequence similarities between DNA molecules. 
  • IgG antibodies from patients with bullous pemphigoid bind to localized epitopes on synthetic peptides encoded by bullous pemphigoid antigen cDNA. 
  • IgG antinuclear antibodies with cross-reactive rheumatoid factor activity. 
  • Imaging molecular pathways: reporter genes. 
  • Immediate decline in DNA synthesis in neonatal rat lung caused by exposure to 100% oxygen. 
  • Immune recognition of DNA in SLE. 
  • Immune responses to DNA in normal and aberrant immunity. 
  • Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit. 
  • Immunologic consequences of acute ethanol ingestion in rats. 
  • Immunologic consequences of nucleic acid therapy. 
  • Immunological properties of bacterial DNA. 
  • Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone. 
  • Impact of CYP2C19 Metabolizer Status on Patients With ACS Treated With Prasugrel Versus Clopidogrel. 
  • Impact of the increased adoption of prenatal cfDNA screening on non-profit patient advocacy organizations in the United States. 
  • Impaired cytoskeletal organization and membrane integrity in lens fibers of a Rho GTPase functional knockout transgenic mouse. 
  • Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes. 
  • Improvements to the differential display method for gene analysis. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers. 
  • In situ synthesis of DNA microarray on functionalized cyclic olefin copolymer substrate. 
  • In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: comparison with its murine parent. 
  • In vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazoles. 
  • In vitro characterization of a mutator T4 DNA polymerase. 
  • In vitro chick embryo cell response to strain MC29 avian leukosis virus. 
  • In vitro selection of aptamers from RNA libraries. 
  • In vitro toxicology of fumonisins and the mechanistic implications. 
  • In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction. 
  • Incorporation of active DNA/cationic polymer polyplexes into hydrogel scaffolds. 
  • Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase. 
  • Incorporation of tritiated thymidine into mononuclear cells of human synovial effusions. 
  • Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures. 
  • Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes. 
  • Increased expression of fibroblast growth factors in a rabbit skeletal muscle model of exercise conditioning. 
  • Increased skin carcinogenesis in caspase-activated DNase knockout mice. 
  • Increasing occurrences and functional roles for high energy purine-pyrimidine base-pairs in nucleic acids. 
  • Independently derived murine glomerular immune deposit-forming anti-DNA antibodies are encoded by near-identical VH gene sequences. 
  • Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers. 
  • Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA. 
  • Induction of cytochrome P(1)450 RNA and benzo[a]pyrene metabolism in primary human hepatocyte cultures with benzanthracene. 
  • Induction of hepatic CYP1A in channel catfish increases binding of 2-aminoanthracene to DNA in vitro and in vivo. 
  • Induction of internucleosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis. 
  • Influence of assay conditions on ELISA determinations of anti-DNA antibodies. 
  • Influence of the extent of hybridization on the hydrodynamic radius of DNA-functionalized gold nanoparticles. 
  • InfoEvolve: moving from data to knowledge using information theory and genetic algorithms. 
  • Infochemistry and infofuses for the chemical storage and transmission of coded information. 
  • Informative priors based on transcription factor structural class improve de novo motif discovery. 
  • Inhibition of DNA binding by differential sumoylation of heat shock factors. 
  • Inhibition of DNA helicase II unwinding and ATPase activities by DNA-interacting ligands. Kinetics and specificity. 
  • Inhibition of DNA synthesis in neonatal rat brain regions caused by acute nicotine administration. 
  • Inhibition of NF-kappa B by S-nitrosylation. 
  • Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. 
  • Inhibition of in vitro NZB antibody responses by cyclosporine. 
  • Inhibition of in vitro anti-DNA B-cell responses by cyclosporine. 
  • Inhibition of murine macrophage IL-12 production by natural and synthetic DNA. 
  • Inhibition of murine macrophage nitric oxide production by synthetic oligonucleotides. 
  • Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells. 
  • Inhibitor of marrow thymidine incorporation from sera of patients with uremia. 
  • Inkless microcontact printing on SAMs of Boc- and TBS-protected thiols. 
  • Inositol polyphosphate 1-phosphatase is present in the nucleus and inhibits DNA synthesis. 
  • Insights into Watson-Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m1A. 
  • Integrated CMOS microchip system with capillary array electrophoresis. 
  • Integrated genomic analyses in bronchopulmonary dysplasia. 
  • Integrating ambiguously aligned regions of DNA sequences in phylogenetic analyses without violating positional homology. 
  • Integration of cell-free protein coexpression with an enzyme-linked immunosorbent assay enables rapid analysis of protein-protein interactions directly from DNA. 
  • Intellectual property. Patents, secrecy, and DNA. 
  • Inter-laboratory comparison of DNA preservation in archival paraffin-embedded human brain tissue from participating centres on four continents. 
  • Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. 
  • Interaction of RNA polymerase II with structurally altered nucleosomal particles. Transcription is facilitated by loss of one H2A.H2B dimer. 
  • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. 
  • Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies. 
  • Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene. 
  • Interlaboratory validation of a new assay for DNA-protein crosslinks. 
  • Interleukin-3 expression by activated T cells involves an inducible, T-cell-specific factor and an octamer binding protein. 
  • International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents. 
  • Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. 
  • Interpolated markov chains for eukaryotic promoter recognition. 
  • Interrupter sequences that are widely distributed in the Drosophila genome. 
  • Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4. 
  • Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene. 
  • Intrachromosomal gene conversion and the maintenance of sequence homogeneity among repeated genes. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Intrinsic disorder within and flanking the DNA-binding domains of human transcription factors. 
  • Intrinsic dynamics of DNA-polymer complexes: a mechanism for DNA release. 
  • Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases. 
  • Investigation of the complexes of EcoRI endonuclease with decanucleotides containing canonical and modified recognition sequences using fluorescence and optical detection of magnetic resonance spectroscopy. 
  • Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles. 
  • Ipr gene control of the anti-DNA antibody response. 
  • Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells. 
  • Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. 
  • Is there left-handed DNA at the ends of yeast chromosomes? 
  • Isolated sulfite oxidase deficiency: identification of 12 novel SUOX mutations in 10 patients. 
  • Isolation and analysis of recombinant DNA molecules containing yeast DNA. 
  • Isolation and characterization of a bovine cDNA encoding a functional homolog of human P-selectin. 
  • Isolation and characterization of a human pro alpha 2(I) collagen gene segment. 
  • Isolation and characterization of a major tandem repeat family from the human X chromosome. 
  • Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of a novel human prostatic stromal cell culture: DuK50. 
  • Isolation and characterization of cDNAs encoding human brain ankyrins reveal a family of alternatively spliced genes. 
  • Isolation and characterization of the gene encoding rat glucose-dependent insulinotropic peptide. 
  • Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin. 
  • Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins. 
  • Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase. 
  • Isolation and structural analysis of the chromosomal gene for chicken calmodulin. 
  • Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes. 
  • Isolation of a cDNA clone complementary to sequences for a 34-kilodalton protein which is a pp60v-src substrate. 
  • Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor. 
  • Isolation of a candidate cDNA for the gene causing retinal degeneration in the rd mouse. 
  • Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant. 
  • Isolation of a rat parvalbumin gene and full length cDNA. 
  • Isolation of cDNA clones for basal lamina components: type IV procollagen. 
  • Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily. 
  • Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. 
  • Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification. 
  • Isolation, characterization, and cDNA cloning of a vampire bat salivary plasminogen activator. 
  • JAK2 is required for induction of the murine DUB-1 gene. 
  • Joint learning from multiple types of genomic data. 
  • Joint modeling of DNA sequence and physical properties to improve eukaryotic promoter recognition. 
  • K+ regulates DNA binding of transcription factors to control gene expression related to neuronal apoptosis. 
  • KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes. 
  • Kallikrein-related mRNAs of the rat submaxillary gland: nucleotide sequences of four distinct types including tonin. 
  • Knockdown of prolactin receptors in a pancreatic beta cell line: effects on DNA synthesis, apoptosis, and gene expression. 
  • Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. 
  • Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence. 
  • Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy. 
  • Label-free DNA biosensor based on SERS Molecular Sentinel on Nanowave chip. 
  • Lac repressor mRNA transcription terminates in vivo in the lac control region. 
  • Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis. 
  • Lack of coactivator interaction can be a mechanism for dominant negative activity by mutant thyroid hormone receptors. 
  • Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. 
  • Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone. 
  • Laser-induced room-temperature phosphorescence detection of benzo[a]pyrene-DNA adducts. 
  • Learning protein-DNA interaction landscapes by integrating experimental data through computational models. 
  • Left-handed DNA helices, supercoiling, and the B-Z junction. 
  • Leprosy in a mangabey monkey--naturally acquired infection. 
  • Life, diversity and the pursuit of haplotypes. 
  • Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. 
  • Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene. 
  • Ligation of the alpha2M signaling receptor with receptor-recognized forms of alpha2-macroglobulin initiates protein and DNA synthesis in macrophages. The effect of intracellular calcium. 
  • Linkage analysis for age-related macular degeneration supports a gene on chromosome 10q26. 
  • Linkage analysis in a family with the Opitz GBBB syndrome refines the location of the gene in Xp22 to a 4 cM region. 
  • Linkage analysis in familial amyotrophic lateral sclerosis. 
  • Linkage analysis in the spinal muscular atrophy type of facioscapulohumeral disease. 
  • Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8. 
  • Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families. 
  • Linkage of Charcot-Marie-Tooth neuropathy type 1a to chromosome 17. 
  • Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse. 
  • Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. 
  • Liposome-mediated conformation transition of DNA detected by molecular probe: methyl green. 
  • Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. 
  • Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall. 
  • Localization of a gene (CMT2A) for autosomal dominant Charcot-Marie-Tooth disease type 2 to chromosome 1p and evidence of genetic heterogeneity. 
  • Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. 
  • Localized DNA Hybridization Chain Reactions on DNA Origami. 
  • Localized delivery of DNA to the cells by viral collagen-loaded silica colloidal crystals. 
  • Location of the 5.8S rRNA gene of Saccharomyces cerevisiae. 
  • Locus heterogeneity, anticipation and reduction of the chromosome 2p minimal candidate region in autosomal dominant familial spastic paraplegia. 
  • Logical computation using algorithmic self-assembly of DNA triple-crossover molecules. 
  • Long poly(A) tracts in the human genome are associated with the Alu family of repeated elements. 
  • Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood. 
  • Long-range charge transport in single G-quadruplex DNA molecules. 
  • Long-term ethanol consumption alters the hepatic response to the regenerative effects of tumor necrosis factor-alpha. 
  • Long-term primary culture of epithelial cells from rainbow trout Oncorhynchus mykiss) liver. 
  • Long-term protein and calorie restriction: alterations in nucleic acid levels of organs of male rats. 
  • Loop Sequence Context Influences the Formation and Stability of the i-Motif for DNA Oligomers of Sequence (CCCXXX)4, where X = A and/or T, under Slightly Acidic Conditions. 
  • Loss of hPot1 function leads to telomere instability and a cut-like phenotype. 
  • Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer. 
  • Loss of tolerance of anti-dsDNA B cells in mice overexpressing CD19. 
  • Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss. 
  • Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice. 
  • MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. 
  • MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type. 
  • MPDA: microarray pooled DNA analyzer. 
  • Macromolecular levels, DNA synthesis and ornithine decarboxylase activity in leg muscles from 6-mercaptopurine-treated rats. 
  • Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV. 
  • Mapping individual cosmid DNAs by direct AFM imaging. 
  • Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. 
  • Mapping nucleosome positions using DNase-seq. 
  • Maternal vitamin A restriction alters biochemical development of the brain in rats. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • Measurement of DNA adducts using surface-enhanced Raman spectroscopy. 
  • Measurement of DNA damage using the comet assay. 
  • Measurement of mouse T cell receptor excision circles. 
  • Measurement of the DNA synthetic capacity of activated lymphocytes: nucleotide triphosphate incorporation by permeabilized cells. 
  • Measurements of a large anisotropy in the swelling of oriented DNA films in aqueous solution. 
  • Mechanism of 5'-directed excision in human mismatch repair. 
  • Mechanism of specific site location and DNA cleavage by EcoR I endonuclease. 
  • Mechanisms for the testicular hypertrophy which follows hemicastration. 
  • Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). 
  • Mechanisms of DNA-mismatch correction. 
  • Mechanisms of activation of the RAW264.7 macrophage cell line by transfected mammalian DNA. 
  • Mechanisms of anti-DNA antibody expression in normal and aberrant immunity. 
  • Mechanisms of anti-DNA production in human and murine SLE. 
  • Mechanisms of autoantibody production in autoimmune MRL mice. 
  • Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin. 
  • Medium-chain acyl-CoA dehydrogenase deficiency: postmortem diagnosis in a case of sudden infant death and neonatal diagnosis of an affected sibling. 
  • Meiotic mapping of yeast ribosomal deoxyribonucleic acid on chromosome XII. 
  • Meiotic recombination between repeated transposable elements in Saccharomyces cerevisiae. 
  • Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops. 
  • Membrane binding of plasmid DNA and endocytic pathways are involved in electrotransfection of mammalian cells. 
  • MetJ repressor interactions with DNA probed by in-cell NMR. 
  • Meta-DNA: synthetic biology via DNA nanostructures and hybridization reactions. 
  • Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. 
  • Metabolism of 1,2-dimethylhydrazine by cultured human colon. 
  • Metabolism of aflatoxin B1, benzo[a]pyrene, and 1,2-dimethylhydrazine by cultured rat and human colon. 
  • Metabolism of benzo[a]pyrene by cultured tracheobronchial tissues from mice, rats, hamsters, bovines and humans. 
  • Metagenomic and small-subunit rRNA analyses reveal the genetic diversity of bacteria, archaea, fungi, and viruses in soil. 
  • Metal-regulated transcription in eukaryotes. 
  • Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. FUSION (Finland-U.S. Investigation of NIDDM Genetics) Study Group. 
  • Methylation of deoxycytidine incorporated by excision-repair synthesis of DNA. 
  • Methylation of the FSHD syndrome-linked subtelomeric repeat in normal and FSHD cell cultures and tissues. 
  • Methylation-specific PCR. 
  • Micro flow bio-molecular computation. 
  • Microfluidic preparation of polymer-nucleic acid nanocomplexes improves nonviral gene transfer. 
  • Microfluidic synthesis of multifunctional Janus particles for biomedical applications. 
  • Microparticles as a source of extracellular DNA. 
  • Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus. 
  • Microparticles as autoadjuvants in the pathogenesis of SLE. 
  • Microparticles as autoantigens in systemic lupus erythematosus. 
  • Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus. 
  • Mild cystic fibrosis linked to chromosome 7q22 markers with an uncommon haplotype. 
  • Mismatch repair and genetic stability in human cells. 
  • Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks. 
  • Mismodeled purines: implicit alternates and hidden Hoogsteens. 
  • Missense mutations in the sodium borate cotransporter SLC4A11 cause late-onset Fuchs corneal dystrophy. 
  • Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease. 
  • Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. 
  • Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection. 
  • Model of creation and evolution of stable electropores for DNA delivery. 
  • Modeling nuclear molecule release during in vitro cell death. 
  • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. 
  • Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells. 
  • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. 
  • Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. 
  • Modular, well-behaved reversible polymers from DNA-based monomers. 
  • Modulation of Hoogsteen dynamics on DNA recognition. 
  • Modulation of macrophage colony stimulating factor in cultured human retinal pigment epithelial cells. 
  • Modulation of potassium transport in cultured retinal pigment epithelium and retinal glial cells by serum and epidermal growth factor. 
  • Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes. 
  • Molecular analysis of highly enriched populations of T-cell-depleted monocytes. 
  • Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency. 
  • Molecular analysis of recombination in a family with Duchenne muscular dystrophy and a large pericentric X chromosome inversion. 
  • Molecular analysis of the 60-kDa human Ro ribonucleoprotein. 
  • Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33. 
  • Molecular basis of defective anion transport in L cells expressing recombinant forms of CFTR. 
  • Molecular biology of gastrointestinal peptides and growth factors: relevance to intestinal adaptation. 
  • Molecular characterization of MHC class II antigens (beta 1 domain) in the BB diabetes-prone and -resistant rat. 
  • Molecular characterization of ribosomal genes on the Ybb- chromosome of Drosophila melanogaster. 
  • Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor. 
  • Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype. 
  • Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. 
  • Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. 
  • Molecular cloning and nucleotide sequence of a cDNA clone coding for the cell attachment domain in human fibronectin. 
  • Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme. 
  • Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA. 
  • Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA. 
  • Molecular cloning and sequencing of zeta-crystallin/quinone reductase cDNA from human liver. 
  • Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites. 
  • Molecular cloning of a new human G protein. Evidence for two Gi alpha-like protein families. 
  • Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulus-response coupling. 
  • Molecular cloning of a novel splice variant of the alpha subunit of the mammalian Go protein. 
  • Molecular cloning of cDNA that encode MHC class I molecules from a New World primate (Saguinus oedipus). Natural selection acts at positions that may affect peptide presentation to T cells. 
  • Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. 
  • Molecular cloning of ovomucoid gene sequences from partially purified ovomucoid messenger RNA. 
  • Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP). 
  • Molecular cloning of the cDNA for androgen-dependent sperm-coating glycoproteins secreted by the rat epididymis. 
  • Molecular cloning of the cDNA for ligatin. 
  • Molecular cloning of the cDNA for two major androgen-dependent secretory proteins of 18.5 kilodaltons synthesized by the rat epididymis. 
  • Molecular evolutionary dynamics of cytochrome b in strepsirrhine primates: the phylogenetic significance of third-position transversions. 
  • Molecular genetic studies of major histocompatibility complex genes in children with juvenile dermatomyositis: increased risk associated with HLA-DQA1 *0501. 
  • Molecular genetics of neurodegenerative diseases. 
  • Molecular heterogeneity in the infantile and juvenile forms of Sandhoff disease (O-variant GM2 gangliosidosis). 
  • Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein. 
  • Molecular mapping of functional domains of the leukocyte receptor for endothelium, LAM-1. 
  • Molecular measurement of T cell receptor excision circles. 
  • Molecular mechanics simulation of the interaction of estrogen receptor with estrogen regulatory element. 
  • Molecular mechanisms of dominant negative activity by nuclear hormone receptors. 
  • Molecular sentinel-on-chip for SERS-based biosensing. 
  • Molecular signals in B cell activation. II. IL-2-mediated signals are required in late G1 for transition to S phase after ionomycin and PMA treatment. 
  • Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene. 
  • Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase. 
  • Molecular structure of the La and Ro autoantigens and their use in autoimmune diagnostics. 
  • Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. 
  • Morphologic and functional studies of mouse hepatocytes in primary culture. 
  • Morphological and biochemical changes which occur during postnatal development and maturation of the rat testis. 
  • Mosaicism for an FMR1 gene deletion in a fragile X female. 
  • Motifs within the CLN3 protein: modulation of cell growth rates and apoptosis. 
  • Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis. 
  • Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2. 
  • Multifunctional hybrid three-dimensionally woven scaffolds for cartilage tissue engineering. 
  • Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. 
  • Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways. 
  • Multiple forms of beta-amyloid peptide precursor RNAs in a single cell type. 
  • Multiple forms of rat liver type I topoisomerase. 
  • Multiple red cell ferritin mRNAs, which code for an abundant protein in the embryonic cell type, analyzed by cDNA sequence and by primer extension of the 5'-untranslated regions. 
  • Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells. 
  • Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip. 
  • Multivariable analysis of DNA ploidy, p53, and HER-2/neu as prognostic factors in endometrial cancer. 
  • Murine polypyrimidine tract binding protein. Purification, cloning, and mapping of the RNA binding domain. 
  • Muscle sodium channel inactivation defect in paramyotonia congenita with the thr1313met mutation. 
  • Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization. 
  • Mutation analysis of the RET receptor tyrosine kinase in Hirschsprung disease. 
  • Mutation analysis of the TSC2 gene in an African-American family. 
  • Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 
  • Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. 
  • Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS). 
  • Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness. 
  • Mutations in acid beta-galactosidase cause GM1-gangliosidosis in American patients. 
  • Mutations in medium chain acyl-CoA dehydrogenase deficiency. 
  • Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease. 
  • Mutations in the medium chain acyl-CoA dehydrogenase (MCAD) gene. 
  • Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes. 
  • Myosin light chain kinase structure function analysis using bacterial expression. 
  • Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene. 
  • NAD+ modulates p53 DNA binding specificity and function. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NF1-related locus on chromosome 15. 
  • NOS2 regulation of NF-kappaB by S-nitrosylation of p65. 
  • Naked DNA delivered intraportally expresses efficiently in hepatocytes. 
  • Nano-C60 cytotoxicity is due to lipid peroxidation. 
  • Nanomechanical fingerprints of UV damage to DNA. 
  • Nanomechanical fingerprints of gamma radiation damage to DNA. 
  • Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements. 
  • Nanoscale detection of ionizing radiation damage to DNA by atomic force microscopy. 
  • Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse. 
  • Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice. 
  • Neuronal control of cardiac and hepatic macromolecule synthesis in the neonatal rat: effects of sympathectomy. 
  • Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart. 
  • Neuronal transfection using particle-mediated gene transfer. 
  • Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. 
  • Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. 
  • New Perspectives in Rheumatology: Biomarkers as Entry Criteria for Clinical Trials of New Therapies for Systemic Lupus Erythematosus: The Example of Antinuclear Antibodies and Anti-DNA. 
  • New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey. 
  • New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone. 
  • New mechanistic and functional insights into DNA topoisomerases. 
  • New nomenclature and DNA testing guidelines for myotonic dystrophy type 1 (DM1). The International Myotonic Dystrophy Consortium (IDMC). 
  • New techniques for DNA sequence classification. 
  • Newly Revised Quantitative PCR-Based Assay for Mitochondrial and Nuclear DNA Damage. 
  • Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos. 
  • Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations. 
  • Nitric oxide synthase 2(Lambaréné) (G-954C), increased nitric oxide production, and protection against malaria. 
  • Nitrosative stress-induced apoptosis through inhibition of NF-kappa B. 
  • No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. 
  • Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells. 
  • Non-viral charge reversal vectors for pDNA delivery. 
  • Nonconsensus Protein Binding to Repetitive DNA Sequence Elements Significantly Affects Eukaryotic Genomes. 
  • Noninvasive fetal RhCE genotyping from maternal blood. 
  • Nonlinear interferometric vibrational imaging. 
  • Nonrandom localization of recombination events in human alpha satellite repeat unit variants: implications for higher-order structural characteristics within centromeric heterochromatin. 
  • Nonspecific interstitial pneumonia, alveolar proteinosis, and abnormal proprotein trafficking resulting from a spontaneous mutation in the surfactant protein C gene. 
  • Norfloxacin-induced DNA gyrase cleavage complexes block Escherichia coli replication forks, causing double-stranded breaks in vivo. 
  • North Carolina macular dystrophy is assigned to chromosome 6. 
  • North, south, or east? Blotting techniques. 
  • Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A. 
  • Novel in vitro gene transfer method for study of local modulators in vascular smooth muscle cells. 
  • Novel mutations in the CLN6 gene causing a variant late infantile neuronal ceroid lipofuscinosis. 
  • Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries. 
  • Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. 
  • Nuclear DNA from primate dug 
  • Nuclear cytoplasmic shuttling by thyroid hormone receptors. multiple protein interactions are required for nuclear retention. 
  • Nuclear inositol signaling: a structural and functional approach. 
  • Nuclear protein CBP is a coactivator for the transcription factor CREB. 
  • Nuclease activity in a fragment of bacteriophage T4 deoxyribonucleic acid polymerase induced by the amber mutant am B22. 
  • Nucleic acid binding drugs--XIV. The crystal structure of 1-methyl amsacrine hydrochloride; relationships to DNA-binding ability and anti-tumour activity. 
  • Nucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responses. 
  • Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert. 
  • Nucleosomes influence multiple steps during replication initiation. 
  • Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family. 
  • Nucleotide sequence of mouse SCIP cDNA, a POU-domain transcription factor. 
  • Nucleotide sequence of the envelope protein genes of a highly virulent, neurotropic strain of Newcastle disease virus. 
  • Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism. 
  • O-Alkyl dioleoylphosphatidylcholinium compounds: the effect of varying alkyl chain length on their physical properties and in vitro DNA transfection activity. 
  • O6-benzylguanine-mediated enhancement of chemotherapy. 
  • Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase. 
  • Ocular status of boys with fragile X syndrome: a prospective study. 
  • Offspring number, pregnancy, and risk of a first clinical demyelinating event: the AusImmune Study. 
  • OligoCalc: an online oligonucleotide properties calculator. 
  • On the origins, structures and functions of restriction-modification enzymes. 
  • Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling. 
  • One-step and stepwise magnification of a bobbed lethal chromosome in Drosophila melanogaster. 
  • Optical mapping of protein-DNA complexes on chromatin fibers. 
  • Optimal sequence selection in proteins of known structure by simulated evolution. 
  • Optimized lymphocyte protein extraction performed simultaneously with DNA and RNA isolation: application to the study of factors affecting DNA, RNA, and protein recovery from lymphocytes of the oldest individuals. 
  • Optimizing aptamer activity for gene therapy applications using expression cassette SELEX. 
  • Orangutan alpha-satellite monomers are closely related to the human consensus sequence. 
  • Organization and evolution of alpha satellite DNA from human chromosome 11. 
  • Organization of the human aromatase p450 (CYP19) gene. 
  • Organization of the human zeta-crystallin/quinone reductase gene (CRYZ). 
  • Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene. 
  • Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. 
  • Ovalbumin gene: purification of the coding strand. 
  • Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner. 
  • Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity. 
  • Overlapping transcription units in the transient receptor potential locus of Drosophila melanogaster. 
  • Ovomucoid intervening sequences specify functional domains and generate protein polymorphism. 
  • Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor. 
  • Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. 
  • Oxidative stress activates anion exchange protein 2 and AP-1 in airway epithelial cells. 
  • Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism. 
  • PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro. 
  • PI3K stimulates DNA synthesis and cell-cycle progression via its p55PIK regulatory subunit interaction with PCNA. 
  • PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: summary of the literature and implications for genetic testing. 
  • PNA versus DNA: effects of structural fluctuations on electronic structure and hole-transport mechanisms. 
  • Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. 
  • Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo. 
  • Parallel molecular computations of pairwise exclusive-or (XOR) using DNA "string tile" self-assembly. 
  • Parathyroid hormone stimulates growth of embryonic chick pelvic cartilage in vitro. 
  • Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice. 
  • Patterns of chromosomal alterations in breast ductal carcinoma in situ. 
  • Peptide elongation factor eEF1A-2/S1 expression in cultured differentiated myotubes and its protective effect against caspase-3-mediated apoptosis. 
  • Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells. 
  • Perinatal dietary supplementation with a commercial soy lecithin preparation: effects on behavior and brain biochemistry in the developing rat. 
  • Perinatal environmental tobacco smoke exposure in rhesus monkeys: critical periods and regional selectivity for effects on brain cell development and lipid peroxidation. 
  • Peroxide-mediated chromatin remodelling of a nuclear factor kappa B site in the mouse inducible nitric oxide synthase promoter. 
  • Personal DNA testing in college classrooms: perspectives of students and professors. 
  • Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning. 
  • Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. 
  • Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity. 
  • Phosphorylation selectively increases triiodothyronine receptor homodimer binding to DNA. 
  • Photocontrolled micellar aggregation of amphiphilic DNA-azobenzene conjugates. 
  • Photoselected electron transfer pathways in DNA photolyase. 
  • Phylogenetic analyses suggest reverse splicing spread of group I introns in fungal ribosomal DNA. 
  • Phylogenetic relationships, morphological incongruence, and geographic speciation in the fontinalaceae (Bryophyta). 
  • Phylogenomic analyses data of the avian phylogenomics project. 
  • Physical and biological properties of cationic triesters of phosphatidylcholine. 
  • Physiologic role for enhanced renal thromboxane production in murine lupus nephritis. 
  • Physiological and molecular basis of thyroid hormone action. 
  • Plasmids for recombination-based screening. 
  • Plasmonic SERS biosensing nanochips for DNA detection. 
  • Plasmonic coupling interference (PCI) nanoprobes for nucleic acid detection. 
  • Plasmonic nanoprobes for SERS biosensing and bioimaging. 
  • Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy. 
  • Plasmonics nanoprobes: detection of single-nucleotide polymorphisms in the breast cancer BRCA1 gene. 
  • Plasmonics-based SERS nanobiosensor for homogeneous nucleic acid detection. 
  • Plasmonics-based nanostructures for surface-enhanced Raman scattering bioanalysis. 
  • Plasticity in the adult human oligodendrocyte lineage. 
  • Poly(ethylene glycol) hydrogel system supports preadipocyte viability, adhesion, and proliferation. 
  • Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA. 
  • Polymorphic repeats in the androgen receptor gene: molecular markers of prostate cancer risk. 
  • Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study. 
  • Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use. 
  • Polymorphisms in BRCA1 and BRCA2 and risk of epithelial ovarian cancer. 
  • Polypeptides of avian RNA tumor viruses. 3. Purification and identification of a DNA synthesizing enzyme. 
  • Polyspecific binding of Escherichia coli beta-galactosidase by murine antibodies to DNA. 
  • Polyspecific reactivity of a murine monoclonal antibody that binds to nuclear matrix-associated, chromatin-bound autoantigens. 
  • Population bottlenecks as a potential major shaping force of human genome architecture. 
  • Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. 
  • Porous hyaluronic acid hydrogels for localized nonviral DNA delivery in a diabetic wound healing model. 
  • Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts. 
  • Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. 
  • Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. 
  • Potential for germ line transmission after intramyocardial gene delivery by adeno-associated virus. 
  • Pre-proglucagon messenger ribonucleic acid: nucleotide and encoded amino acid sequences of the rat pancreatic complementary deoxyribonucleic acid. 
  • Precise arrangement of factor-binding sites is required for murine CD4 promoter function. 
  • Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). 
  • Preferential DNA-protein cross-linking by NiCl2 in magnesium-insoluble regions of fractionated Chinese hamster ovary cell chromatin. 
  • Preferential formation and repair of chromium-induced DNA adducts and DNA--protein crosslinks in nuclear matrix DNA. 
  • Preferential synthesis of yeast mitochondrial DNA in alpha factor-arrested cells. 
  • Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus. 
  • Preliminary perspectives on DNA collection in anti-human trafficking efforts. 
  • Preliminary x-ray diffraction studies of EcoRI restriction endonuclease-DNA complex. 
  • Prenatal cocaine and cell development in rat brain regions: effects on ornithine decarboxylase and macromolecules. 
  • Prenatal diagnosis and carrier detection for glycogen storage disease type III using polymorphic DNA markers. 
  • Prenatal diagnosis and genetic analysis of X chromosome polysomy 49, XXXXY. 
  • Prenatal diagnosis and genetic analysis of double trisomy 48,XXX,+18. 
  • Prenatal exclusion of Ehlers-Danlos syndrome type VI by mutational analysis. 
  • Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth. 
  • Prenatal exposure to propranolol via continuous maternal infusion: effects on physiological and biochemical processes mediated by beta adrenergic receptors in fetal and neonatal rat lung. 
  • Preparation of 5-[131I]iodo- and 5-[211At]astato-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil by a halodestannylation reaction. 
  • Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR. 
  • Presence of large deletions in kindreds with autism. 
  • Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy. 
  • Prevention of H2O2 generation by monoamine oxidase protects against CNS O2 toxicity. 
  • Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. 
  • Priming with plasmid DNAs expressing interleukin-12 and simian immunodeficiency virus gag enhances the immunogenicity and efficacy of an experimental AIDS vaccine based on recombinant vesicular stomatitis virus. 
  • Probabilistic Analysis of Localized DNA Hybridization Circuits. 
  • Probing sequence-specific DNA flexibility in a-tracts and pyrimidine-purine steps by nuclear magnetic resonance (13)C relaxation and molecular dynamics simulations. 
  • Probing transient Hoogsteen hydrogen bonds in canonical duplex DNA using NMR relaxation dispersion and single-atom substitution. 
  • Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. 
  • Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes. 
  • Programmable DNA self-assemblies for nanoscale organization of ligands and proteins. 
  • Programmed cell death induced by ceramide. 
  • Programming DNA tube circumferences. 
  • Prokaryotic transcription regulators: more than just the helix-turn-helix motif. 
  • Proliferation of Double-Strand Break-Resistant Polyploid Cells Requires Drosophila FANCD2. 
  • Prolonged skin photosensitization induced by methoxsalen and subphototoxic UVA irradiation. 
  • Promoter hypermethylation profile of kidney cancer. 
  • Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination. 
  • Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult. 
  • Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling. 
  • Prospects for personalized cardiovascular medicine: the impact of genomics. 
  • Prostaglandin F2 alpha-induced mitogenesis in MC3T3-E1 osteoblasts: role of protein kinase-C-mediated tyrosine phosphorylation. 
  • Protein Composition of TGFBI-R124C- and TGFBI-R555W-Associated Aggregates Suggests Multiple Mechanisms Leading to Lattice and Granular Corneal Dystrophy. 
  • Protein phosphatase 5 is required for ATR-mediated checkpoint activation. 
  • Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair. 
  • Protein-DNA binding in the absence of specific base-pair recognition. 
  • Protein-DNA binding: complexities and multi-protein codes. 
  • Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex. 
  • Pulling geometry-induced errors in single molecule force spectroscopy measurements. 
  • Pulmonary fibrogenesis after three consecutive inhalation exposures to chrysotile asbestos. 
  • Pulse Field Gel Electrophoresis. 
  • Pulsed-field gel electrophoresis. 
  • Purine-specific reapir of beta-propiolacton-induced DNA damage in mouse skin cells. 
  • Putative telomere-recruiting domain in the catalytic subunit of human telomerase. 
  • Quality of DNA extracted from mouthwashes. 
  • Quantification of normal cell death in the rat retina: implications for clone composition in cell lineage analysis. 
  • Quantitative DNA pooling to increase the efficiency of linkage analysis in autosomal dominant disease. 
  • Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. 
  • Quantitative modeling of transcription factor binding specificities using DNA shape. 
  • Quasielastic light scattering by biopolymers. Conformation of chromatin multimers. 
  • Quenching of DNA cross-link precursors of chloroethylnitrosoureas and attenuation of DNA interstrand cross-linking by glutathione. 
  • RFLP identified by the anonymous DNA segment pBAM34 at 19q13.3-qter [HGM8 assignment D19S6]. 
  • RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue. 
  • RNA transfected dendritic cells as cancer vaccines. 
  • RNA-transfected dendritic cells in cancer immunotherapy. 
  • RNA∶DNA hybrids initiate quasi-palindrome-associated mutations in highly transcribed yeast DNA. 
  • RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Rabbits immunized with a peptide encoded for by the 230-kD bullous pemphigoid antigen cDNA develop an enhanced inflammatory response to UVB irradiation: a potential animal model for bullous pemphigoid. 
  • Radiation-induced genomic instability: radiation quality and dose response. 
  • Randomised trial of plasma exchange in mild systemic lupus erythematosus. 
  • Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. 
  • Rapid DNA sequencing of more than 1000 bases per run by capillary electrophoresis using replaceable linear polyacrylamide solutions. 
  • Rapid analysis of small nucleic acid samples by gel electrophoresis. 
  • Rapid communication: BamHI restriction fragment length polymorphism detected with a pig gastric mucin (MUC5AC) probe. 
  • Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. 
  • Rapid evolution of cis-regulatory sequences via local point mutations. 
  • Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites. 
  • Rat amylin: cloning and tissue-specific expression in pancreatic islets. 
  • Rat granulosa cells express transforming growth factor-beta type 2 messenger ribonucleic acid which is regulatable by follicle-stimulating hormone in vitro. 
  • Recent advances in nanoparticle-mediated siRNA delivery. 
  • Receptor binding, endocytosis, and mitogenesis of insulin-like growth factors I and II in fetal rat brain neurons. 
  • Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems. 
  • Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. 
  • Recombinant human interleukin 1 alpha: purification and biological characterization. 
  • Recombination of 4p16 DNA markers in an unusual family with Huntington disease. 
  • Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity. 
  • Recommendations for national and local regulatory authorities concerning research in genetic markers of disease. 
  • Reconfigurable core-satellite nanoassemblies as molecularly-driven plasmonic switches. 
  • Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. 
  • Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. 
  • Reduction of folic acid-induced acute tubular injury by diuresis: an experimental model. 
  • Reduction of intimal hyperplasia and enhanced reactivity of experimental vein bypass grafts with verapamil treatment. 
  • Refined localization of human connexin32 gene locus, GJB1, to Xq13.1. 
  • Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes. 
  • Region-specific anti-thyroid hormone receptor (TR) antibodies detect changes in TR structure due to ligand-binding and dimerization. 
  • Region-specific antiglucocorticoid receptor antibodies selectively recognize the activated form of the ligand-occupied receptor and inhibit the binding of activated complexes to deoxyribonucleic acid. 
  • Regulation of Clara cell secretory protein gene transcription by thyroid transcription factor-1. 
  • Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. 
  • Regulation of NF-kappaB action by reversible acetylation. 
  • Regulation of Sertoli cell function and differentiation through the actions of a testicular paracrine factor P-Mod-S. 
  • Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene. 
  • Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I. 
  • Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. 
  • Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. 
  • Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. 
  • Regulation of the human interleukin-3 gene. 
  • Regulation of tyrosine hydroxylase mRNA by glucocorticoid and cyclic AMP in a rat pheochromocytoma cell line. Isolation of a cDNA clone for tyrosine hydroxylase mRNA. 
  • Regulation of tyrosine hydroxylase mRNA by glucocorticoid and cyclic AMP in a rat pheochromocytoma cell line. Isolation of a cDNA clone for tyrosine hydroxylase mRNA. 
  • Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells. 
  • Regulatory and structural motifs of chicken gizzard myosin light chain kinase. 
  • Regulatory gene networks and the properties of the developmental process. 
  • Relationship between adipose stromal-vascular cells and adipocytes in human adipose tissue. 
  • Relationships among DNA sequences of the 1.3 kb EcoRI family of mouse DNA. 
  • Relaxin treatment of solid tumors: effects on electric field-mediated gene delivery. 
  • Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro. 
  • Remarkable conservation of structure among intermediate filament genes. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus. 
  • Replication control of autonomously replicating human sequences. 
  • Replication of the TCF4 intronic variant in late-onset Fuchs corneal dystrophy and evidence of independence from the FCD2 locus. 
  • Replication of yeast chromosomal DNA. 
  • Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus. 
  • Replication, recombination, and repair: going for the gold. 
  • Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. 
  • Report of the X chromosome workshop. 
  • Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1. 
  • Restricted expression of WT1 messenger ribonucleic acid in immature ovarian follicles: uniformity in mammalian and avian species and maintenance during reproductive senescence. 
  • Retention of the native chondrocyte pericellular matrix results in significantly improved matrix production. 
  • Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase. 
  • Retrospective family study of childhood medulloblastoma. 
  • Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer. 
  • Revealing noncovalent interactions. 
  • Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor. 
  • RhoB-dependent modulation of postendocytic traffic in polarized Madin-Darby canine kidney cells. 
  • Ribozyme-mediated revision of RNA and DNA. 
  • Robust IR-based detection of stable and fractionally populated G-C+ and A-T Hoogsteen base pairs in duplex DNA. 
  • Role for topoisomerase 1 in transcription-associated mutagenesis in yeast. 
  • Role of Conformational Fluctuations of Protein toward Methylation in DNA by Cytosine-5-methyltransferase. 
  • Role of DNA binding sites and slow unbinding kinetics in titration-based oscillators. 
  • Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium. 
  • Role of macrophages in the generation of circulating blood nucleosomes from dead and dying cells. 
  • Role of molecular biology in hypertension research. State of the Art lecture. 
  • Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. 
  • Role of the 2-amino group of deoxyguanosine in sequence recognition by EcoRI restriction and modification enzymes. 
  • Roles of 3,5,3'-triiodothyronine and deoxyribonucleic acid binding on thyroid hormone receptor complex formation. 
  • Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. 
  • SAQC: SNP array quality control. 
  • SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. 
  • SOS induction as an in vivo assay of enzyme-DNA interactions. 
  • SRA coactivation of estrogen receptor-alpha is phosphorylation-independent, and enhances 4-hydroxytamoxifen agonist activity. 
  • Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial. 
  • Salivary testosterone and a trinucleotide (CAG) length polymorphism in the androgen receptor gene predict amygdala reactivity in men. 
  • Satellite DNA sequences of Drosophila melanogaster. 
  • Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants. 
  • Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. 
  • Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel. 
  • Search for genes involved in Joubert syndrome: evidence that one or more major loci are yet to be identified and exclusion of candidate genes EN1, EN2, FGF8, and BARHL1. 
  • Sedimentation properties of yeast chromosomal DNA. 
  • Selective conservation of GAP-43 structure in vertebrate evolution. 
  • Selective inhibition of Alu retrotransposition by APOBEC3G. 
  • Selective recognition of DNA antigenic determinants by murine monoclonal anti-DNA antibodies. 
  • Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles. 
  • Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. 
  • Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway. 
  • Separating DNA with different topologies by atomic force microscopy in comparison with gel electrophoresis. 
  • Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage. 
  • Sequence complexity of nuclear RNAs in adult rat tissues. 
  • Sequence features of DNA binding sites reveal structural class of associated transcription factor. 
  • Sequence of full length cDNA for human S-adenosylhomocysteine hydrolase. 
  • Sequence of the cDNA for the alpha subunit of calmodulin kinase II from mouse brain. 
  • Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. 
  • Sequence-specific B-DNA flexibility modulates Z-DNA formation. 
  • Sequencing and analysis of genomic fragments from the NF1 locus. 
  • Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix. 
  • Sequenom v. Ariosa - The Death of a Genetic Testing Patent. 
  • Serotonin transporter gene polymorphism and antidepressant response. 
  • Serum immunoglobulin levels in systemic lupus erythematosus: the effects of age, sex, race and disease duration. 
  • Serum withdrawal induces apoptotic cell death in Ki-ras transformed but not in normal differentiated thyroid cells. 
  • Shift in nucleosome populations during embryogenesis: microheterogeneity in nucleosomes during development of the sea urchin embryo. 
  • Shortest nucleosomal repeat lengths during sea urchin development are found in two-cell embryos. 
  • Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz. 
  • Signatures of protein-DNA recognition in free DNA binding sites. 
  • Silver impairs neurodevelopment: studies in PC12 cells. 
  • Simple Mendelian inheritance of the reiterated ribosomal DNA of yeast. 
  • Single molecule mechanical manipulation for studying biological properties of proteins, DNA, and sugars. 
  • Single- and dual-fractal analysis of hybridization binding kinetics: biosensor applications. 
  • Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α. 
  • Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II. 
  • Site-directed mutagenesis of the inhibitory subunit of retinal rod cyclic GMP phosphodiesterase. 
  • Size and structure of yeast chromosomal DNA. 
  • Size-controlled lipid nanoparticle production using turbulent mixing to enhance oral DNA delivery. 
  • Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering. 
  • Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase. 
  • SnapShot: Origins of DNA replication. 
  • Snapshot of the allele-specific variation in human gene expression. 
  • Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla. 
  • Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. 
  • Solution structure of the core NFATC1/DNA complex. 
  • Somatic mutation of TRbeta can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor. 
  • Somatic uniparental disomy of Chromosome 16p in hemimegalencephaly. 
  • Something old, something new. 
  • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. 
  • Specificity analysis of monoclonal anti-DNA antibodies. 
  • Specificity and idiotype analysis of a monoclonal anti-DNA antibody. 
  • Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity. 
  • Specificity and immunochemical properties of anti-DNA antibodies induced in normal mice by immunization with mammalian DNA with a CpG oligonucleotide as adjuvant. 
  • Specificity and immunochemical properties of antibodies to bacterial DNA. 
  • Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. 
  • Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage. 
  • Spontaneous expression of antibodies to DNA of various species origin in sera of normal subjects and patients with systemic lupus erythematosus. 
  • Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. 
  • Stability of the topoisomerase II closed clamp conformation may influence DNA-stimulated ATP hydrolysis. 
  • Stability selection for regression-based models of transcription factor-DNA binding specificity. 
  • Standardization of anti-DNA antibody assays. 
  • Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. 
  • Statistics for ChIP-chip and DNase hypersensitivity experiments on NimbleGen arrays. 
  • Stepwise self-assembly of DNA tile lattices using dsDNA bridges. 
  • Steroid hormone receptors selectively affect transcriptional activation but not basal repression by thyroid hormone receptors. 
  • Stimulation of DNA synthesis in human epidermis by UVB radiation and its inhibition by difluoromethylornithine. 
  • Stimulation of inducible nitric oxide synthase in rat liver by hyaluronan fragments. 
  • Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. 
  • Stress and death: breaking up the c-Abl/14-3-3 complex in apoptosis. 
  • Stretching single molecules into novel conformations using the atomic force microscope. 
  • Strong founder effect in Drosophila pseudoobscura colonizing New Zealand from North America. 
  • Structural analysis of the human BIN1 gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing. 
  • Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectin. 
  • Structural and functional domains of the Drosophila ncd microtubule motor protein. 
  • Structural and functional studies of cyclic GMP phosphodiesterase. 
  • Structural and immunological comparison of indigenous human O6-methylguanine-DNA methyltransferase with that encoded by a cloned cDNA. 
  • Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P. 
  • Structural basis of beta-adrenergic receptor subtype specificity studied with chimeric beta 1/beta 2-adrenergic receptors. 
  • Structural basis of core promoter recognition in a primitive eukaryote. 
  • Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregation. 
  • Structural differences in the chromatin from compartmentalized cells of the sea urchin embryo: differential nuclease accessibility of micromere chromatin. 
  • Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase. 
  • Structural mechanisms of QacR induction and multidrug recognition. 
  • Structural organization and chromosomal assignment of the parvalbumin gene. 
  • Structural organization and regulation of the chicken estrogen receptor. 
  • Structural relationships in glycogen phosphorylases. 
  • Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain. 
  • Structure and filament dynamics of the pSK41 actin-like ParM protein: implications for plasmid DNA segregation. 
  • Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse. 
  • Structure and function of the UvrB protein. 
  • Structure and regulation of the chicken erythroid delta-aminolevulinate synthase gene. 
  • Structure and regulation of the murine Clara cell secretory protein gene. 
  • Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage. 
  • Structure and stability of monomeric lambda repressor: NMR evidence for two-state folding. 
  • Structure of DNA in DNA replication mutants of yeast. 
  • Structure of DNA polymerase I Klenow fragment bound to duplex DNA. 
  • Structure of a G.T.A triplet in an intramolecular DNA triplex. 
  • Structure of a Z-DNA with two different backbone chain conformations. Stabilization of the decadeoxyoligonucleotide d(CGTACGTACG) by [Co(NH3)6]3+ binding to the guanine. 
  • Structure of a tethered cationic 3-aminopropyl chain incorporated into an oligodeoxynucleotide: evidence for 3'-orientation in the major groove accompanied by DNA bending. 
  • Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein. 
  • Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy. 
  • Structure of the eukaryotic transcription apparatus: features of the gene for the largest subunit of Drosophila RNA polymerase II. 
  • Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1). 
  • Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils. 
  • Structures and mechanisms of DNA restriction and modification enzymes. 
  • Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. 
  • Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. 
  • Structures of mismatch replication errors observed in a DNA polymerase. 
  • Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. 
  • Studies leading to the isolation of a cDNA for the gene causing retinal degeneration in the rd mouse. 
  • Studies of the regulatory mechanism of Ca2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate. 
  • Studies on DNA replication in the bacteriophage T4 in vitro system. 
  • Studies on mode of action of vitamin A. 
  • Studies on scaffold attachment sites and their relation to genome function. 
  • Studies on sequence recognition by type II restriction and modification enzymes. 
  • Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants. 
  • Study design for genetic analysis in the Jackson Heart Study. 
  • Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. 
  • Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification. 
  • Successful renal transplantation in patients with chronic granulomatous disease. 
  • Supplemental putrescine reverses ethanol-associated inhibition of liver regeneration. 
  • Suppression of human corneal epithelial proliferation with breast carcinoma immunotoxin. 
  • Surface- and Hydrogel-Mediated Delivery of Nucleic Acid Nanoparticles. 
  • Surface- and hydrogel-mediated delivery of nucleic acid nanoparticles. 
  • Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures. 
  • Surface-tethered DNA complexes for enhanced gene delivery. 
  • Surface-to-surface bridges formed by reversibly assembled polymers. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211. 
  • Sustained release of plasmid DNA using lipid microtubules and agarose hydrogel. 
  • Synaptonemal complex karyotyping in spermatocytes of the Chinese hamster (Cricetulus griseus). III. Quantitative evaluation. 
  • Synergistic enhancement of both initiation and elongation by acidic transcription activation domains. 
  • Synergistic induction of nuclear factor-kappaB by transforming growth factor-beta and tumour necrosis factor-alpha is mediated by protein kinase A-dependent RelA acetylation. 
  • Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct. 
  • Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase. 
  • Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease. 
  • Synthesis of DNA coding for human proinsulin. 
  • Synthesis of fluorosurfactants for emulsion-based biological applications. 
  • Synthesis of single-stranded hybridization probes from reusable DNA templates bound to solid support. 
  • Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery. 
  • Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. 
  • Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration. 
  • Systematic gene mapping in man: data management considerations. 
  • Systemic lupus erythematosus: a matter of life and death. 
  • T locus shows no evidence for linkage disequilibrium or mutation in American Caucasian neural tube defect families. 
  • T296----M, a common mutation causing mild hemophilia B in the Amish and others: founder effect, variability in factor IX activity assays, and rapid carrier detection. 
  • TFBSshape: a motif database for DNA shape features of transcription factor binding sites. 
  • Targeted expression of calmodulin increases ventricular cardiomyocyte proliferation and deoxyribonucleic acid synthesis during mouse development. 
  • Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice. 
  • Technology evaluation: Rexin-G, Epeius Biotechnologies. 
  • Telomerase activity in normal leukocytes and in hematologic malignancies. 
  • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. 
  • Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage. 
  • Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation. 
  • The 185/333 gene family is a rapidly diversifying host-defense gene cluster in the purple sea urchin Strongylocentrotus purpuratus. 
  • The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro. 
  • The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae. 
  • The Alarmin Properties of DNA and DNA-associated Nuclear Proteins. 
  • The B-cell repertoire for autoantibodies: frequency of precursor cells for anti-DNA antibodies. 
  • The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology. 
  • The DNA binding domain of a papillomavirus E2 protein programs a chimeric nuclease to cleave integrated human papillomavirus DNA in HeLa cervical carcinoma cells. 
  • The DNA-binding homeo domain of the Oct-2 protein. 
  • The Drosophila glutathione S-transferase 1-1 is encoded by an intronless gene at 87B. 
  • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. 
  • The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase. 
  • The Haemophilus influenzae Hia autotransporter contains an unusually short trimeric translocator domain. 
  • The International HapMap Project. 
  • The Krüppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. 
  • The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter. 
  • The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. 
  • The PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial: study rationale, design, and baseline patient characteristics. 
  • The RNAissance period. 
  • The RosR transcription factor is required for gene expression dynamics in response to extreme oxidative stress in a hypersaline-adapted archaeon. 
  • The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals. 
  • The Saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties. 
  • The Staphylococcus aureus pSK41 plasmid-encoded ArtA protein is a master regulator of plasmid transmission genes and contains a RHH motif used in alternate DNA-binding modes. 
  • The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. 
  • The Top1 paradox: Friend and foe of the eukaryotic genome. 
  • The Use of Poly-L-Lysine as a Capture Agent to Enhance the Detection of Antinuclear Antibodies by ELISA. 
  • The accessible chromatin landscape of the human genome. 
  • The activation domain of the MotA transcription factor from bacteriophage T4. 
  • The alpha 1C-adrenergic receptor: a new member in the alpha 1-adrenergic receptor family. 
  • The androgen-binding protein gene is expressed in CD1 mouse testis. 
  • The anti-La response of a single MRL/Mp-lpr/lpr mouse: specificity for DNA and VH gene usage. 
  • The antigenic properties of bacterial DNA in normal and aberrant immunity. 
  • The apolipoprotein E epsilon2 allele and aging-associated health deterioration in older males. 
  • The beta-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus. 
  • The binding of 7,12-dimethylbenz(A)anthracene to replicating and non-replicating DNA in cell culture. 
  • The binding of sera of patients with SLE to bacterial and mammalian DNA. 
  • The biological functions of DNA: from the sublime to the slime. 
  • The blood nucleome in the pathogenesis of SLE. 
  • The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages. 
  • The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation. 
  • The clinical utility of measuring complement and anti-dsDNA antibodies during pregnancy in patients with systemic lupus erythematosus. 
  • The common acute lymphoblastic leukemia antigen (neutral endopeptidase-3.4.24.11) gene is located on human chromosome 3. 
  • The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. 
  • The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis. 
  • The dopamine transporter. The cloned target site of parkinsonism-inducing toxins and of drugs of abuse. 
  • The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex. 
  • The effect of age on the accumulation of labile triosephosphate isomerase and thymidine incorporation in pokeweed mitogen stimulated human lymphocytes. 
  • The effect of charge-reversal amphiphile spacer composition on DNA and siRNA delivery. 
  • The effect of dexamethasone on the generation of plasma DNA from dead and dying cells. 
  • The effect of inflammation on the generation of plasma DNA from dead and dying cells in the peritoneum. 
  • The effect of octreotide on hepatic regeneration in rats. 
  • The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects. 
  • The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos. 
  • The effect of transforming growth factor-beta on follicle-stimulating hormone-induced differentiation of cultured rat granulosa cells. 
  • The effects of CpG DNA on HMGB1 release by murine macrophage cell lines. 
  • The effects of aging on phosphofructokinase induction during lymphocyte mitogenesis in relation to DNA and protein synthesis. 
  • The effects of crosslinking of scaffolds engineered from cartilage ECM on the chondrogenic differentiation of MSCs. 
  • The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death. 
  • The fine specificity of monoclonal anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. 
  • The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response. 
  • The gamma delta T cell receptor. 
  • The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis. 
  • The generation of extracellular DNA in SLE: the role of death and sex. 
  • The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2. 
  • The helix-turn-helix DNA binding motif. 
  • The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence. 
  • The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells. 
  • The human T-cell leukemia virus-1 transcriptional activator Tax enhances cAMP-responsive element-binding protein (CREB) binding activity through interactions with the DNA minor groove. 
  • The human aminopeptidase N gene: isolation, chromosome localization, and DNA polymorphism analysis. 
  • The identification and characterization of KRAB-domain-containing zinc finger proteins. 
  • The immune response to cell death in SLE. 
  • The immunologic properties of DNA. 
  • The induction of HMGB1 release from RAW 264.7 cells by transfected DNA. 
  • The influence of DNA size on the binding of antibodies to DNA in the sera of normal human subjects and patients with systemic lupus erythematosus (SLE). 
  • The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens. 
  • The influence of base sequence on the immunological properties of defined oligonucleotides. 
  • The influence of base sequence on the immunostimulatory properties of DNA. 
  • The influence of variable-region somatic mutations on the specificity and pathogenicity of murine monoclonal anti-DNA antibodies. 
  • The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers. 
  • The isolation of ecdysterone inducible genes by hybridization subtraction chromatography. 
  • The large DNA insert cloning workshop. 
  • The licensing of DNA patents by US academic institutions: an empirical survey. 
  • The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus). 
  • The loop domain of heat shock transcription factor 1 dictates DNA-binding specificity and responses to heat stress. 
  • The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 families. 
  • The mechanism of steroid-hormone regulation of transcription of specific eukaryotic genes. 
  • The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. 
  • The moderately repetitive DNA sequences of Caenorhabditis elegans do not show short-period interspersion. 
  • The mouse Cd83 gene: structure, domain organization, and chromosome localization. 
  • The mouse homolog of the human amyloid beta protein (AD-AP) gene is located on the distal end of mouse chromosome 16: further extension of the homology between human chromosome 21 and mouse chromosome 16. 
  • The mouse retinoid-X receptor-gamma gene: genomic organization and evidence for functional isoforms. 
  • The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2. 
  • The non-covalent interaction of pyrrolo[2, 1-c] [1, 4]benzodiazepine-5, 11-diones with DNA. 
  • The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. 
  • The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. 
  • The origin and properties of extracellular DNA: from PAMP to DAMP. 
  • The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells transfected with human DNA. 
  • The origin of extracellular DNA during the clearance of dead and dying cells. 
  • The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic. 
  • The other function of DNA photolyase: stimulation of excision repair of chemical damage to DNA. 
  • The ovalbumin gene. Partial purification of the coding strand. 
  • The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. 
  • The peripheral myelin protein gene PMP-22 is contained within the Charcot-Marie-Tooth disease type 1A duplication. 
  • The polymorphic locus for glycogen storage disease VI (liver glycogen phosphorylase) maps to chromosome 14. 
  • The potassium channel MBK1 (Kv1.1) is expressed in the mouse retina. 
  • The probability of HLA-C matching between patient and unrelated donor at the molecular level: estimations based on the linkage disequilibrium between DNA typed HLA-B and HLA-C alleles. 
  • The production of transforming growth factor-beta activity by rat granulosa cell cultures. 
  • The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis. 
  • The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis. 
  • The release of DNA into the plasma of mice following hepatic cell death by apoptosis and necrosis. 
  • The role of Smad3 in mediating mouse hepatic stellate cell activation. 
  • The role of aspirin and dipyridamole on vascular DNA synthesis and intimal hyperplasia following deendothelialization. 
  • The role of carbohydrate in the function of human plasminogen: comparison of the protein obtained from molecular cloning and expression in Escherichia coli and COS cells. 
  • The role of cell surface receptors in the activation of human B cells by phosphorothioate oligonucleotides. 
  • The role of extracellular DNA in autoimmunity in SLE. 
  • The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. 
  • The role of macrophages in the in vitro generation of extracellular DNA from apoptotic and necrotic cells. 
  • The role of monogamous bivalency and Fc interactions in the binding of anti-DNA antibodies to DNA antigen. 
  • The role of nuclear macromolecules in innate immunity. 
  • The role of ultrasound in women who undergo cell-free DNA screening. 
  • The spliceosome assembly pathway in mammalian extracts. 
  • The structural basis for the mutagenicity of O(6)-methyl-guanine lesions. 
  • The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. 
  • The structural organization of the chicken calmodulin gene. 
  • The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding. 
  • The synthesis and antineoplastic activity of 2'-deoxy-nucleoside-cyanoboranes in murine and human culture cells. 
  • The use of fluorometric assays to assess the immune response to DNA in murine systemic lupus erythematosus. 
  • The use of single nucleotide polymorphisms in the isolation of common disease genes. 
  • The vitamin D receptor: a primitive steroid receptor related to thyroid hormone receptor. 
  • The winged-helix DNA-binding motif: another helix-turn-helix takeoff. 
  • Thermal denaturation of DNA from bromodeoxyuridine substituted cells. 
  • Thermodynamic parameters governing interaction of EcoRI endonuclease with specific and nonspecific DNA sequences. 
  • Thermodynamics of DNA hybridization on gold nanoparticles. 
  • Thirteen Mhc-DQA1 alleles from two populations of baboons. 
  • Thousand-fold increase in optical storage density by polychromatic address multiplexing on self-assembled DNA nanostructures. 
  • Three Pyrimidine Decarboxylations in the Absence of a Catalyst. 
  • Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes. 
  • Three-dimensional culture systems to induce chondrogenesis of adipose-derived stem cells. 
  • Three-helix bundle DNA tiles self-assemble into 2D lattice or 1D templates for silver nanowires. 
  • Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. 
  • Thromboxane receptor blockade reduces renal injury in murine lupus nephritis. 
  • Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature. 
  • Thyroid hormone differentially regulates cellular development in neonatal rat heart and kidney. 
  • Thyroid hormone response elements differentially modulate the interactions of thyroid hormone receptors with two receptor binding domains in the steroid receptor coactivator-1. 
  • Tilting at windmills no longer: a data-driven discussion of DTC DNA ancestry tests. 
  • Time and distance dependence of reversible polymer bridging followed by single-molecule force spectroscopy. 
  • Tissue-engineered bone formation with gene transfer and mesenchymal stem cells in a minimally invasive technique. 
  • Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family. 
  • Tissue-specific expression of kallikrein-related genes in the rat. 
  • Tissue-specific expression of the rat androgen-binding protein/sex hormone-binding globulin gene in transgenic mice. 
  • Tissue-specific gene expression in mouse F9 embryonal carcinoma cells: type IV collagen. 
  • Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad. 
  • Topical methotrexate therapy for psoriasis. 
  • Topoisomerase II inhibition and altered kinetics of formation and repair of nitrosourea and cisplatin-induced DNA interstrand cross-links and cytotoxicity in human glioblastoma cells. 
  • Torsional behavior of chromatin is modulated by rotational phasing of nucleosomes. 
  • Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes. 
  • Trans-synaptic increase in RNA coding for tyrosine hydroxylase in a rat sympathetic ganglion. 
  • Transcription as a source of genome instability. 
  • Transcription inhibits the replication of autonomously replicating plasmids in human cells. 
  • Transcription of H-2 and Qa genes in embryonic and adult mice. 
  • Transcriptional inhibition by carcinogenic chromate: relationship to DNA damage. 
  • Transcriptional regulation by the numbers: applications. 
  • Transcriptional regulation of T lymphocyte development and function. 
  • Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin. 
  • Transfection in the third dimension. 
  • Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. 
  • Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element. 
  • Transforming growth factor-beta 1 and mannose 6-phosphate/insulin-like growth factor-II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat. 
  • Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations. 
  • Transient Hoogsteen base pairs in canonical duplex DNA. 
  • Transient expression of a winged-helix protein, MNF-beta, during myogenesis. 
  • Transiently overexpressed alpha2-adrenoceptors and their control of DNA synthesis in the developing brain. 
  • Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes. 
  • Transrectal gene therapy of the prostate in the canine model. 
  • Transversions have larger regulatory effects than transitions. 
  • Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats. 
  • Treatment with a laminin-derived peptide suppresses lupus nephritis. 
  • Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers. 
  • Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA. 
  • Truncated STAT proteins are prevalent at relapse of acute myeloid leukemia. 
  • Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide. 
  • Tumor multiplicity, DNA adducts and K-ras mutation pattern of 5-methylchrysene in strain A/J mouse lung. 
  • Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. 
  • Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver. 
  • Tumor necrosis factor-alpha and tumor growth factor-beta1 genotype: partial association with intragraft gene expression in two cases of long-term peripheral tolerance to a kidney transplant. 
  • Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. 
  • Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein. 
  • Two and three-dimensional gene transfer from enzymatically degradable hydrogel scaffolds. 
  • Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. 
  • Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. 
  • Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer. 
  • Tyloxapol inhibits NF-kappa B and cytokine release, scavenges HOCI, and reduces viscosity of cystic fibrosis sputum. 
  • Type 1 neurofibromatosis gene: correction. 
  • UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y(6) receptors. 
  • UV absorption complicates PCR decontamination. 
  • UVA generates pyrimidine dimers in DNA directly. 
  • Ultrastructural Analysis of Vesicular Transport in Electrotransfection. 
  • Unusual DNA sequences associated with the ends of yeast chromosomes. 
  • Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. 
  • Unusual chromosome architecture and behaviour at an HSR. 
  • Update on the molecular genetics of Duchenne muscular dystrophy. 
  • Use of SYTO 13, a fluorescent dye binding nucleic acids, for the detection of microparticles in in vitro systems. 
  • Use of eukaryotic expression technology in the functional analysis of cloned genes. 
  • Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution. 
  • Using DNA duplex stability information for transcription factor binding site discovery. 
  • Validation of DNA-based HLA-A and HLA-B testing of volunteers for a bone marrow registry through parallel testing with serology. 
  • Variable region sequence analysis of anti-DNA antibodies: evidence for a family of closely related germ-line VH genes encoding lupus autoantibodies. 
  • Variation in DNA and RNA synthetic responses during activation of lymphocytes from inbred strains of mice. 
  • Variation in the microbiome of the urogenital tract of Chlamydia-free female koalas (Phascolarctos cinereus) with and without 'wet bottom'. 
  • Variations in opsin coding sequences cause x-linked cone dysfunction syndrome with myopia and dichromacy. 
  • Verification of self-report of zygosity determined via DNA testing in a subset of the NAS-NRC twin registry 40 years later. 
  • Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes. 
  • Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein. 
  • Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. 
  • Voltage-induced long-range coherent electron transfer through organic molecules. 
  • Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. 
  • When the checkpoints have gone: insights into Cdc25 functional activation. 
  • Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA? 
  • Widespread transient Hoogsteen base pairs in canonical duplex DNA with variable energetics. 
  • Workshop on cancer biometrics: identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health. 
  • X-linked neuropathy: gene localization with DNA probes. 
  • X-linked severe combined immunodeficiency. Diagnosis in males with sporadic severe combined immunodeficiency and clarification of clinical findings. 
  • Xenobiotic induction of quinone oxidoreductase activity in lens epithelial cells. 
  • Y353/B: a candidate multiple-copy spermiogenesis gene on the mouse Y chromosome. 
  • Yeast chromosomal DNA: size, structure, and replication. 
  • Zinc finger protein binding to DNA: an energy perspective using molecular dynamics simulation and free energy calculations on mutants of both zinc finger domains and their specific DNA bases. 
  • [Quantitative study of the cellular nuclear DNA contents in odontogenic cysts and ameloblastoma]. 
  • beta-Arrestin: a protein that regulates beta-adrenergic receptor function. 
  • beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. 
  • c-Jun enhancement of cyclic adenosine 3',5'-monophosphate response element-dependent transcription induced by transforming growth factor-beta is independent of c-Jun binding to DNA. 
  • cAMP-dependent protein kinase is necessary for increased NF-E2.DNA complex formation during erythroleukemia cell differentiation. 
  • cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase. 
  • cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. 
  • cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product. 
  • cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. 
  • cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. 
  • cis-acting elements that confer lung epithelial cell expression of the CC10 gene. 
  • eNOS, a pressure-dependent regulator of intraocular pressure. 
  • p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. 
• 

  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Allori, Alexander C, Assistant Professor of Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Professor of Pediatrics, in the School of Medicine, Immunology
  • Chen, Jun, Associate Professor of Medicine, Duke Cancer Institute
  • Cianciolo, George James, Associate Professor in Pathology, Pathology
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Gordan, Raluca Mihaela, Associate Professor in Biostatistics & Bioinformatics, Molecular Genetics and Microbiology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Kearney, Hutton Moore, Assistant Consulting Professor in the Department of Pathology, Pathology
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology
  • Middleton, John Paul, Associate Professor of Medicine, Medicine, Nephrology
  • Moorman, Patricia Gripka, Professor in Family Medicine and Community Health, Duke Cancer Institute
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics, Molecular Genetics and Microbiology
  • Reif, John H., A. Hollis Edens Professor of Computer Science, Electrical and Computer Engineering
  • Sullivan, Beth Ann, Associate Professor of Molecular Genetics and Microbiology, Duke Science & Society
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Wray, Gregory Allan, Professor of Biology, Duke Innovation & Entrepreneurship
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Zhang, Zhiquan, Assistant Professor in Anesthesiology, Anesthesiology