DNA

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  Subject Areas on Research

  • "Smart" DNA interfaces. 
  • * CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. 
  • 172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant. 
  • 1H NMR spectroscopy of DNA. 
  • 2'-deoxy-5-azacytidine increases binding of cisplatin to DNA by a mechanism independent of DNA hypomethylation. 
  • 4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors. 
  • A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. 
  • A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter. 
  • A DNA nanotransport device powered by polymerase phi29. 
  • A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. 
  • A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation. 
  • A candidate taste receptor gene near a sweet taste locus. 
  • A cis-acting sequence homologous to the yeast filamentation and invasion response element regulates expression of a pectinase gene from the bean pathogen Colletotrichum lindemuthianum. 
  • A combination DNA and attenuated simian immunodeficiency virus vaccine strategy provides enhanced protection from simian/human immunodeficiency virus-induced disease. 
  • A compound nucleotide repeat in the neurofibromatosis (NF1) gene. 
  • A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding. 
  • A de novo frame-shift mutation in the tuberin gene. 
  • A defined human system that supports bidirectional mismatch-provoked excision. 
  • A duplication in chromosome 4q35 is associated with hereditary benign intraepithelial dyskeratosis. 
  • A family of human Y chromosomes has dispersed throughout northern Eurasia despite a 1.8-Mb deletion in the azoospermia factor c region. 
  • A fragile X male with a broad smear on Southern blot analysis representing 100-500 CGG repeats and no methylation at the EagI site of the FMR-1 gene. 
  • A functional analysis of the spacer of V(D)J recombination signal sequences. 
  • A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain. 
  • A genetic association study of the mu opioid receptor and severe opioid dependence. 
  • A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. 
  • A high proportion of ADA point mutations associated with a specific alanine-to-valine substitution. 
  • A highly efficient strategy to determine genotypes of genetically-engineered mice using genomic DNA purified from hair roots. 
  • A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers. 
  • A historical account of Hoogsteen base-pairs in duplex DNA. 
  • A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. 
  • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. 
  • A long-range flexible billboard model of gene activation. 
  • A maximum-likelihood base caller for DNA sequencing. 
  • A mixed epigenetic/genetic model for oligogenic inheritance of autism with a limited role for UBE3A. 
  • A multimember kinesin gene family in Drosophila. 
  • A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro. 
  • A neural-specific GAP-43 core promoter located between unusual DNA elements that interact to regulate its activity. 
  • A neutrophil derived factor(s) stimulates [3H]thymidine incorporation by vascular smooth muscle cells in vitro. 
  • A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions. 
  • A new phase in the study of human inherited eye diseases. 
  • A new strategy for studying protein kinase B and its three isoforms. Role of protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin, WNK1, and ATP citrate lyase. 
  • A new tightly linked DNA probe for myotonic dystrophy. 
  • A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. 
  • A noncanonical function of cGAMP in inflammasome priming and activation. 
  • A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene. 
  • A novel beta-globin mutation, beta Durham-NC [beta 114 Leu-->Pro], produces a dominant thalassemia-like phenotype. 
  • A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. 
  • A novel polypeptide secreted by activated human T lymphocytes. 
  • A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. 
  • A novel process for optimizing musculoskeletal allograft tissue to improve safety, ultrastructural properties, and cell infiltration. 
  • A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs. 
  • A pathway-based classification of human breast cancer. 
  • A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation. 
  • A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice. 
  • A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci. 
  • A recombination-based assay demonstrates that the fragile X sequence is transcribed widely during development. 
  • A relocated technique of atomic force microscopy (AFM) samples and its application in molecular biology. 
  • A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus. 
  • A serial study of splenic reticuloendothelial system Fc receptor functional activity in systemic lupus erythematosus. 
  • A simple BASIC program allows the rapid entry of DNA nucleotide sequences into personal computers. 
  • A simple enzyme-linked immunosorbent assay for antibodies to native DNA. 
  • A single molecule detection method for understanding mechanisms of electric field-mediated interstitial transport of genes. 
  • A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC). 
  • A tale of tails: how histone tails mediate chromatin compaction in different salt and linker histone environments. 
  • A three-dimensional ParF meshwork assembles through the nucleoid to mediate plasmid segregation. 
  • A transcription factor affinity-based code for mammalian transcription initiation. 
  • A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation. 
  • A two-state DNA lattice switched by DNA nanoactuator. 
  • A unidirectional DNA walker that moves autonomously along a track. 
  • A yeast artificial chromosome contig encompassing the type 1 neurofibromatosis gene. 
  • ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. 
  • ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background. 
  • Absence of a simple code: how transcription factors read the genome. 
  • Absence of mutation in the beta-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's disease. 
  • Accuracy of BRCA1 and BRCA2 founder mutation analysis in formalin-fixed and paraffin-embedded (FFPE) tissue. 
  • Activation of human B cells by phosphorothioate oligodeoxynucleotides. 
  • Activation of the Saccharomyces cerevisiae heat shock transcription factor under glucose starvation conditions by Snf1 protein kinase. 
  • Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. 
  • Activin expression by cultured human retinal pigment epithelial cells. 
  • Activity of psoralen-functionalized nanoscintillators against cancer cells upon X-ray excitation. 
  • Acute tubular necrosis. An experimental model detailing the biochemical events accompanying renal injury and recovery. 
  • Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements. 
  • Admission cell free DNA levels predict 28-day mortality in patients with severe sepsis in intensive care. 
  • Adrenergic modulation of cardiac development in the rat: effects of prenatal exposure to propranolol via continuous maternal infusion. 
  • Adsorption capacity of multiple DNA sources to clay minerals and environmental soil matrices less than previously estimated. 
  • Advances in the determination of nucleic acid conformational ensembles. 
  • Age at maturity in wild baboons: genetic, environmental and demographic influences. 
  • Age distribution of latent herpes simplex virus 1 and varicella-zoster virus genome in human nervous tissue. 
  • Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. 
  • Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library. 
  • Alpers' syndrome presenting with seizures and multiple stroke-like episodes in a 17-year-old male. 
  • Alpha 1-adrenergic effects and liver regeneration. 
  • Alpha 2-macroglobulin binds CpG oligodeoxynucleotides and enhances their immunostimulatory properties by a receptor-dependent mechanism. 
  • Alteration of NF-kappa B p50 DNA binding kinetics by S-nitrosylation. 
  • Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing. 
  • Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism. 
  • Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells. 
  • Amplified on-chip fluorescence detection of DNA hybridization by surface-initiated enzymatic polymerization. 
  • Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes. 
  • An HLA class II region restriction fragment length polymorphism (RFLP) in patients with dermatitis herpetiformis: association with HLA-DP phenotype. 
  • An autonomously self-assembling dendritic DNA nanostructure for target DNA detection. 
  • An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. 
  • An examination of the monophyly of morning glory taxa using Bayesian phylogenetic inference. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau. 
  • An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent. 
  • Analog Computation by DNA Strand Displacement Circuits. 
  • Analogs of tetrahydroisoquinoline natural products that inhibit cell migration and target galectin-3 outside of its carbohydrate-binding site. 
  • Analysis of Drosophila melanogaster satellite IV with restriction endonuclease MboII. 
  • Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins. 
  • Analysis of cleavage complexes using reactive inhibitor derivatives. 
  • Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. 
  • Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. 
  • Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro. 
  • Analysis of the Stargardt disease gene (ABCR) in age-related macular degeneration. 
  • Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila. 
  • Analyzing cell cycle checkpoints after ionizing radiation. 
  • Anti-DNA and autoantibodies. 
  • Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. 
  • Anti-DNA antibodies in systemic lupus erythematosus. 
  • Anti-DNA antibodies in systemic lupus erythematosus: a case of mistaken identity? 
  • Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats. 
  • Antibodies to DNA. A perspective. 
  • Antibodies to DNA: infection or genetics? 
  • Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. 
  • Antibody responses to DNA in normal immunity and aberrant immunity. 
  • Antimitotic and cytotoxic effects of theophylline in MDA-MB-231 human breast cancer cells. 
  • ApoE genotype and survival from intracerebral haemorrhage. 
  • Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition. 
  • Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase. 
  • Apoptosis in human retinal degenerations. 
  • Apoptosis in the cervix of pregnant rats in association with cervical softening. 
  • Apoptosis is the mode of cell death caused by carcinogenic chromium. 
  • Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. 
  • Application of random peptide phage display to the study of nuclear hormone receptors. 
  • Arabidopsis SNI1 and RAD51D regulate both gene transcription and DNA recombination during the defense response. 
  • Architecture of the human regulatory network derived from ENCODE data. 
  • Arithmetic difficulties in females with the fragile X premutation. 
  • Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. 
  • Ascorbic acid accumulates in cartilage in vivo. 
  • Ascorbic acid specifically increases type I and type III procollagen messenger RNA levels in human skin fibroblast. 
  • Assembly and molecular activities of the MutS tetramer. 
  • Assembly of alternating polycation and DNA multilayer films by electrostatic layer-by-layer adsorption. 
  • Assignment of the human glycogen debrancher gene to chromosome 1p21. 
  • Association between the V109G polymorphism of the p27 gene and the risk and progression of oral squamous cell carcinoma. 
  • Association of TP53 mutational status and gender with survival after adjuvant treatment for stage III colon cancer: results of CALGB 89803. 
  • Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. 
  • Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study. 
  • Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery. 
  • Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender. 
  • Association of the viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids. 
  • Astatine-211-labeled radiotherapeutics: an emerging approach to targeted alpha-particle radiotherapy. 
  • Atypical features of familial hemophagocytic lymphohistiocytosis. 
  • Autoantibodies and their idiotypes. 
  • Autocrine and paracrine effects of atrial natriuretic peptide gene transfer on vascular smooth muscle and endothelial cellular growth. 
  • Autofeedback suppression of growth hormone (GH) secretion in transgenic mice expressing a human GH reporter targeted by tyrosine hydroxylase 5'-flanking sequences to the hypothalamus. 
  • Autoimmunity: the nuclear arsenal of autoimmunity. 
  • Automated constraint-based nucleotide sequence selection for DNA computation. 
  • Autosomal-dominant distal myopathy associated with a recurrent missense mutation in the gene encoding the nuclear matrix protein, matrin 3. 
  • Autosomal-dominant retinitis pigmentosa associated with an Arg-135-Trp point mutation of the rhodopsin gene. Clinical features and longitudinal observations. 
  • BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions. 
  • BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. 
  • Bacterial artificial chromosome cloning and mapping of a 630-kb human extrachromosomal structure. 
  • Bacterial expression and characterization of proteins derived from the chicken calmodulin cDNA and a calmodulin processed gene. 
  • Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair and the regulation of DNA replication origins. 
  • Barriers to productive transfection of trabecular meshwork cells. 
  • Basal forebrain moderates the magnitude of task-dependent amygdala functional connectivity. 
  • Base stacking and molecular polarizability: effect of a methyl group in the 5-position of pyrimidines. 
  • Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons. 
  • Base-specific arrest of in vitro DNA replication by carcinogenic chromium: relationship to DNA interstrand crosslinking. 
  • Bcl-2 accelerates multistep prostate carcinogenesis in vivo. 
  • Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development. 
  • Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization. 
  • Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. 
  • Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions. 
  • Binding specificity of a monoclonal anti-DNA antibody. 
  • Biochemical and molecular homogeneity in the patellar tendon of the immature pig. 
  • Biochemical determinants of growth sparing during neonatal nutritional deprivation or enhancement: ornithine decarboxylase, polyamines, and macromolecules in brain regions and heart. 
  • Biochemical development of the rat lung: studies on cellular DNA, RNA and protein content in relation to maternal vitamin A status. 
  • Biochemical evidence for programmed cell death in rabbit uterine epithelium. 
  • Biochemistry. Scaling up DNA computation. 
  • Biomaterial-mediated retroviral gene transfer using self-assembled monolayers. 
  • Biophysics of knotting. 
  • Bisulfite induces tandem double CC-->TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination. 
  • Blood-sample processing for the study of age-dependent gene expression in peripheral blood mononuclear cells. 
  • Bombesin increases fetal lung growth and maturation in utero and in organ culture. 
  • Boranophosphate nucleic acids--a versatile DNA backbone. 
  • Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort. 
  • Bromodeoxyuridine induction of deoxycytidine deaminase activity in a hamster cell line. 
  • Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells. 
  • C3orf58, a novel paracrine protein, stimulates cardiomyocyte cell-cycle progression through the PI3K-AKT-CDK7 pathway. 
  • CCAAT/enhancer-binding protein alpha is required for transcription of the beta 3-adrenergic receptor gene during adipogenesis. 
  • CD10/neutral endopeptidase 24.11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin-like peptides. 
  • COL5A1: fine genetic mapping and exclusion as candidate gene in families with nail-patella syndrome, tuberous sclerosis 1, hereditary hemorrhagic telangiectasia, and Ehlers-Danlos Syndrome type II. 
  • COOH-terminal requirements for the correct processing of a phosphatidylinositol-glycan anchored membrane protein. 
  • Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms. 
  • Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. 
  • Calcineurin regulates cyclin D1 accumulation in growth-stimulated fibroblasts. 
  • Calcium, calmodulin and cell proliferation. 
  • Calmodulin as a mediator of hormone action and cell regulation. 
  • Calspermin is a testis specific calmodulin-binding protein closely related to Ca2+/calmodulin-dependent protein kinases. 
  • Canine model and genomic structural organization of glycogen storage disease type Ia (GSD Ia). 
  • Cas9 loosens its grip on off-target sites. 
  • Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. 
  • Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. 
  • Cell cycle analysis of budding yeast using SYTOX Green. 
  • Cell-Free DNA Screening: Complexities and Challenges of Clinical Implementation. 
  • Cell-free DNA analysis for noninvasive examination of trisomy. 
  • Cellular events during sexual development from amoeba to plasmodium in the slime mould Physarum polycephalum. 
  • Cellular mechanisms of cyclophosphamide resistance: model studies in human medulloblastoma cell lines. 
  • Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA. 
  • Characteristics associated with participation in DNA banking: The National Registry of Veterans with ALS. 
  • Characterization and expression of the complementary DNA encoding rat histidine decarboxylase. 
  • Characterization and property of DNA incorporated bilayer lipid membranes. 
  • Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors. 
  • Characterization of DNA lesions induced by CaCrO4 in synchronous and asynchronous cultured mammalian cells. 
  • Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21. 
  • Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes. 
  • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. 
  • Characterization of a partial cDNA for lysyl hydroxylase from human skin fibroblasts; lysyl hydroxylase mRNAs are regulated differently by minoxidil derivatives and hydralazine. 
  • Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy. 
  • Characterization of alpha 2-macroglobulin binding to human trabecular meshwork cells: presence of the alpha 2-macroglobulin signaling receptor. 
  • Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli. 
  • Characterization of cDNAs encoding the polypyrimidine tract-binding protein. 
  • Characterization of de novo duplications in eight patients by using fluorescence in situ hybridization with chromosome-specific DNA libraries. 
  • Characterization of human brain cDNA encoding the general isoform of beta-spectrin. 
  • Characterization of human prorenin expressed in mammalian cells from cloned cDNA. 
  • Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L. 
  • Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene. 
  • Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels. 
  • Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. 
  • Characterization of the statin-like S1 and rat elongation factor 1 alpha as two distinctly expressed messages in rat. 
  • Characterization of the tissue regression process in the uterus of older mice as apoptotic by the presence of Tp30, an isoform of terminin. 
  • Characterization of two types of yeast ribosomal DNA genes. 
  • Characterizing the protonation state of cytosine in transient G·C Hoogsteen base pairs in duplex DNA. 
  • Charge Transport across DNA-Based Three-Way Junctions. 
  • Chemical evidence for early but unsustained growth in the obstructed mouse kidney. 
  • Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides. 
  • Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas. 
  • Chicken calmodulin genes. A species comparison of cDNA sequences and isolation of a genomic clone. 
  • Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. 
  • Chiral control of electron transmission through molecules. 
  • Chlorpyrifos exposure during neurulation: cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood. 
  • Cholera toxin and cell growth: role of membrane gangliosides. 
  • Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture. 
  • Chromatin perturbations during the DNA damage response in higher eukaryotes. 
  • Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle. 
  • Chromium-induced genotoxicity and apoptosis: relationship to chromium carcinogenesis (review). 
  • Chromosomal localization of human glutamate receptor genes. 
  • Chromosomal localization of the mouse Src-like adapter protein (Slap) gene and its putative human homolog SLA. 
  • Chromosomal localization of two genes underlying late-infantile neuronal ceroid lipofuscinosis. 
  • Chromosomal organization of adrenergic receptor genes. 
  • Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript. 
  • Clinical and functional findings in choroideremia due to complete deletion of the CHM gene. 
  • Clinical heterogeneity in lymphoedema-distichiasis with FOXC2 truncating mutations. 
  • Cloning and characterization of rat-brain-specific transcripts: rare, brain-specific transcripts and tyrosine hydroxylase. 
  • Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. 
  • Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters. 
  • Cloning and expression of full-length cDNA encoding human vitamin D receptor. 
  • Cloning and functional characterization of a cocaine-sensitive dopamine transporter. 
  • Cloning and molecular characterization of a cDNA clone to statin, a protein specifically expressed in nonproliferating quiescent and senescent fibroblasts. 
  • Cloning of DNA corresponding to rare transcripts of rat brain: evidence of transcriptional and post-transcriptional control and of the existence of nonpolyadenylated transcripts. 
  • Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19. 
  • Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors. 
  • Cloning of the cDNA for the human beta 1-adrenergic receptor. 
  • Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. 
  • Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family. 
  • Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family. 
  • Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. 
  • Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells. 
  • Coarse-Grained Theory of Biological Charge Transfer with Spatially and Temporally Correlated Noise. 
  • Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions. 
  • Cocrystal structure of an editing complex of Klenow fragment with DNA. 
  • Cocultures of adult and juvenile chondrocytes compared with adult and juvenile chondral fragments: in vitro matrix production. 
  • Commitment to cell death is signaled by the appearance of a terminin protein of 30 kDa. 
  • Comparative incorporation of P32 into lung phosphatidyl choline in mammals with different metabolic and pulmonary morphologic characteristics. 
  • Comparative metabolism and excretion of benzo(a)pyrene in 2 species of ictalurid catfish. 
  • Comparative proteomic analysis of cell cycle-dependent apoptosis induced by transforming growth factor-beta. 
  • Comparative studies on the secondary structure of ovalbumin messenger RNA and its complementary DNA transcript. 
  • Comparison of human and Xenopus GATA-2 promoters. 
  • Comparison of pulmonary and pleural responses of rats and hamsters to inhaled refractory ceramic fibers. 
  • Compensatory renal growth after unilateral ureteral obstruction. 
  • Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. 
  • Complete genomic screen in late-onset familial Alzheimer's disease. 
  • Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5' untranslated sequence. 
  • Complexity reduction in context-dependent DNA substitution models. 
  • Composition and transport properties of human ankle and knee cartilage. 
  • Computing. Successes and challenges. 
  • Confirmation of a second locus for CMT2 and evidence for additional genetic heterogeneity. 
  • Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. 
  • Conformational transition of DNA induced by cationic lipid vesicle in acidic solution: spectroscopy investigation. 
  • Conformationally Gated Charge Transfer in DNA Three-Way Junctions. 
  • Connecting the nanodots: programmable nanofabrication of fused metal shapes on DNA templates. 
  • Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation. 
  • Construction and control of plasmid DNA network. 
  • Contractile proteins in Drosophila development. 
  • Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. 
  • Coordinate reduction of rat pancreatic islet glucokinase and proinsulin mRNA by exercise training. 
  • Coordination of DNA ends during double-strand-break repair in bacteriophage T4. 
  • Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency. 
  • Correlation of total and interstrand DNA adducts in tumor and kidney with antitumor efficacies and differential nephrotoxicities of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin. 
  • Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system. 
  • Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man. 
  • Critical role of chromium (Cr)-DNA interactions in the formation of Cr-induced polymerase arresting lesions. 
  • Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. 
  • Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. 
  • Crystal structure of the transcription activator BmrR bound to DNA and a drug. 
  • Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. 
  • Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin. 
  • Cyclic AMP mediated GSTP1 gene activation in tumor cells involves the interaction of activated CREB-1 with the GSTP1 CRE: a novel mechanism of cellular GSTP1 gene regulation. 
  • Cyclin D/CDK4/6 activity controls G1 length in mammalian cells. 
  • Cytokine production at the site of disease in human tuberculosis. 
  • Cytokinetic and molecular pharmacology studies of arabinosylcytosine in metastatic melanoma. 
  • Cytological evidence of transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. 
  • D2 dopamine receptors in the human retina: cloning of cDNA and localization of mRNA. 
  • DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin. 
  • DNA adducts and exposure to burning oil. 
  • DNA and immunoglobulin synthesis by rabbit peripheral blood lymphocytes in vitro: complete and incomplete stimulation. 
  • DNA as a marker of cell death in systemic lupus erythematosus. 
  • DNA copy number evolution in Drosophila cell lines. 
  • DNA damage induces phosphorylation of the amino terminus of p53. 
  • DNA delivery from matrix metalloproteinase degradable poly(ethylene glycol) hydrogels to mouse cloned mesenchymal stem cells. 
  • DNA methyltransferase levels and altered CpG methylation in the total genome and in the GSTP1 gene in human glioma cells transfected with sense and antisense DNA methyltransferase cDNA. 
  • DNA mismatch repair: functions and mechanisms. 
  • DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires. 
  • DNA network structures on various solid substrates investigated by atomic force microscopy. 
  • DNA patents and diagnostics: not a pretty picture. 
  • DNA polymerase arrest by adducted trivalent chromium. 
  • DNA repair in human leukaemic lymphocytes. 
  • DNA robots sort as they walk. 
  • DNA sequence analysis and restriction fragment length polymorphism (RFLP) typing of the HLA-DQw2 alleles associated with dermatitis herpetiformis. 
  • DNA strand breakage by wheat germ type 1 topoisomerase. 
  • DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. 
  • DNA surveillance: web-based molecular identification of whales, dolphins, and porpoises. 
  • DNA typing for HLA-A and HLA-B identifies disparities between patients and unrelated donors matched by HLA-A and HLA-B serology and HLA-DRB1. 
  • DNA vaccination. A clue to memory? 
  • DNA-enabled integrated molecular systems for computation and sensing. 
  • DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells. 
  • DNA-templated self-assembly of protein and nanoparticle linear arrays. 
  • DNA-templated self-assembly of protein arrays and highly conductive nanowires. 
  • DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). 
  • DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types. 
  • DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells. 
  • Dating branches on the tree of life using DNA. 
  • De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence. 
  • Decellularized native and engineered arterial scaffolds for transplantation. 
  • Decreased cochlear DNA receptor staining in MRL.MpJ-Fas(lpr) autoimmune mice with hearing loss. 
  • Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. 
  • Defects in mononuclear phagocytic system (MPS) function in autoimmune MRL-lpr/lpr mice. 
  • Defending information-free genocentrism. 
  • Defining functional DNA elements in the human genome. 
  • Definition of the cellular mechanisms which distinguish between hormone and antihormone activated steroid receptors. 
  • Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation. 
  • Delimiting species without nuclear monophyly in Madagascar's mouse lemurs. 
  • Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. 
  • Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1. 
  • Design and characterization of microporous hyaluronic acid hydrogels for in vitro gene transfer to mMSCs. 
  • Design and construction of double-decker tile as a route to three-dimensional periodic assembly of DNA. 
  • Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). 
  • Detecting colorectal cancer in stool with the use of multiple genetic targets. 
  • Detecting solvent-driven transitions of poly(A) to double-stranded conformations by atomic force microscopy. 
  • Detecting ultraviolet damage in single DNA molecules by atomic force microscopy. 
  • Detection of proximal colorectal cancers through analysis of faecal DNA. 
  • Determinants of deoxyadenosine toxicity in hybrids between human T- and B- lymphoblasts as a model for the development of drug resistance in T-cell acute lymphoblastic leukemia. 
  • Development of autoantibodies before the clinical onset of systemic lupus erythematosus. 
  • Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1. 
  • Developmental cholinotoxicants: nicotine and chlorpyrifos. 
  • Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio). 
  • Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation. 
  • Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. 
  • Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. 
  • Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration. 
  • Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period? 
  • Developmental pattern of DNA and proteins in brain, liver, lung and heart of rats given excess vitamin A postnatally. 
  • Developmental pattern of the hepatic DNA, RNA and protein in relation to maternal vitamin A status in rats. 
  • Developmental toxicity of terbutaline: critical periods for sex-selective effects on macromolecules and DNA synthesis in rat brain, heart, and liver. 
  • Diagnosis of mitochondrial trifunctional protein deficiency in a blood spot from the newborn screening card by tandem mass spectrometry and DNA analysis. 
  • Diagnostic accuracy of noninvasive fetal Rh genotyping from maternal blood--a meta-analysis. 
  • Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex. 
  • Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis. 
  • Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression. 
  • Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans. 
  • Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes. 
  • Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo. 
  • Differential replication of satellite DNA in polyploid tissues of Drosophila virilis. 
  • Differential sensitivity of chromium-mediated DNA interstrand crosslinks and DNA-protein crosslinks to disruption by alkali and EDTA. 
  • Differential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sites. 
  • Differential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces. 
  • Differentially labeled mutant oligonucleotides for analysis of protein-DNA interactions. 
  • Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents. 
  • Dinucleotide repeat polymorphism at the human erythropoietin receptor locus (EPOR) at 19p13. 
  • Dioxinlike properties of a trichloroethylene combustion-generated aerosol. 
  • Direct MHC class I complementary DNA transfer to thymus induces donor-specific unresponsiveness, which involves multiple immunologic mechanisms. 
  • Direct measurements of base stacking interactions in DNA by single-molecule atomic-force spectroscopy. 
  • Directed enzymatic activation of 1-D DNA tiles. 
  • Directed nucleation assembly of DNA tile complexes for barcode-patterned lattices. 
  • Disappearance of statin, a protein marker for non-proliferating and senescent cells, following serum-stimulated cell cycle entry. 
  • Discovering sequences with potential regulatory characteristics. 
  • Discovery of protein- and DNA-imperceptible nanoparticle hard coating using gel-based reaction tuning. 
  • Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis. 
  • Disruption of rat forebrain development by glucocorticoids: critical perinatal periods for effects on neural cell acquisition and on cell signaling cascades mediating noradrenergic and cholinergic neurotransmitter/neurotrophic responses. 
  • Dissecting the differences between the alpha and beta anomers of the oxidative DNA lesion FaPydG. 
  • Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins. 
  • Dissociation of bacteriophage T4 DNA polymerase and its processivity clamp after completion of Okazaki fragment synthesis. 
  • Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. 
  • Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression. 
  • Distinctive subtypes of bovine phospholipase C that have preferential expression in the retina and high homology to the norpA gene product of Drosophila. 
  • Distribution of 5-methyldeoxycytidine in products of staphylococcal nuclease digestion of nuclei and purified DNA. 
  • Distribution of repair-incorporated nucleotides and nucleosome rearrangement in the chromatin of normal and xeroderma pigmentosum human fibroblasts. 
  • Divergence between the Drosophila pseudoobscura and D. persimilis genome sequences in relation to chromosomal inversions. 
  • Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins. 
  • Does concurrent or prior nicotine exposure interact with neonatal hypoxia to produce cardiac cell damage? 
  • Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats. 
  • Does prenatal nicotine exposure sensitize the brain to nicotine-induced neurotoxicity in adolescence? 
  • Domain organization of chicken gizzard myosin light chain kinase deduced from a cloned cDNA. 
  • Domain structure and DNA binding regions of beta protein from bacteriophage lambda. 
  • Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. 
  • Donor-bridge-acceptor energetics determine the distance dependence of electron tunneling in DNA. 
  • Double-strand breaks associated with repetitive DNA can reshape the genome. 
  • Down-regulation of transforming growth factor beta receptor type I, II, and III during liver regeneration. 
  • Drosophila follicle cell amplicons as models for metazoan DNA replication: a cyclinE mutant exhibits increased replication fork elongation. 
  • Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins. 
  • Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry. 
  • Dynamic basis for dG•dT misincorporation via tautomerization and ionization. 
  • Dynamical treatment of charge transfer through duplex nucleic acids containing modified adenines. 
  • Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch. 
  • Early estrogen action: concomitant stimulations within two minutes of nuclear RNA synthesis and uptake of RNA precursor by the uterus. 
  • EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme. 
  • Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. 
  • Effect of DNA conformation on cisplatin adduct formation. 
  • Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice. 
  • Effect of cytofectins on the immune response of murine macrophages to mammalian DNA. 
  • Effect of epidermal growth factor on ornithine decarboxylase activity in A431 cells. 
  • Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. 
  • Effect of nickel(II) on DNA-protein binding, thymidine incorporation, and sedimentation pattern of chromatin fractions from intact mammalian cells. 
  • Effect of proximal transposition of the ileum on mucosal growth and enzyme activity in orally nourished rats. 
  • Effect of transient hydronephrosis on subsequent compensatory renal growth. 
  • Effect os xid on anti-DNA B-cell precursors. 
  • Effects of MK-801 on DNA synthesis in neonatal rat brain regions under normoxic and hypoxic conditions. 
  • Effects of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase, on nucleic acids and proteins in developing rat brain: critical perinatal periods for regional selectivity. 
  • Effects of ammonium ion derived from bovine endothelial cells upon low density lipoprotein degradation in cultured vascular smooth muscle cells. 
  • Effects of benzo[a]pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site. 
  • Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers. 
  • Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation. 
  • Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth. 
  • Effects of continuous diazepam administration on GABAA subunit mRNA in rat brain. 
  • Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR). 
  • Effects of environmental tobacco smoke exposure in utero and/or postnatally on brain development. 
  • Effects of glutathione on chromium-induced DNA crosslinking and DNA polymerase arrest. 
  • Effects of inversions on within- and between-species recombination and divergence. 
  • Effects of neonatal methylmercury exposure on development of nucleic acids and proteins in rat brain: regional specificity. 
  • Effects of nickel(II) on nuclear protein binding to DNA in intact mammalian cells. 
  • Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps. 
  • Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. 
  • Effects of prenatal terbutaline exposure on cellular development in lung and liver of neonatal rat: ornithine decarboxylase activity and macromolecules. 
  • Effects of pulse strength and pulse duration on in vitro DNA electromobility. 
  • Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans. 
  • Effects of source of DNA on genotyping success rates and allele percentages in the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS). 
  • Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene. 
  • Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial. 
  • Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. 
  • Efficient random subcloning of DNA sheared in a recirculating point-sink flow system. 
  • Electric field of a six-needle array electrode used in drug and DNA delivery in vivo: analytical versus numerical solution. 
  • Elevation of cAMP is required for down-regulation, but not agonist-induced desensitization, of endogenous dopamine D1 receptors in opossum kidney cells. Studies in cells that stably express a rat cAMP phosphodiesterase (rPDE3) cDNA. 
  • Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates. 
  • Emergence of the keratinocyte growth factor multigene family during the great ape radiation. 
  • Encoded multichromophore response for simultaneous label-free detection. 
  • Endogenous polymers of ADP-ribose are associated with the nuclear matrix. 
  • Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. 
  • Endonuclease cleavage of blocked replication forks: An indirect pathway of DNA damage from antitumor drug-topoisomerase complexes. 
  • Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages. 
  • Endotoxin-mediated nitric oxide synthesis inhibits IL-1beta gene transcription in ANA-1 murine macrophages. 
  • Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. 
  • Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas. 
  • Enhanced catalytic DNAzyme for label-free colorimetric detection of DNA. 
  • Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells. 
  • Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone. 
  • Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements. 
  • Enzymatic fabrication of DNA nanostructures: extension of a self-assembled oligonucleotide monolayer on gold arrays. 
  • Epigenetic detection of human chromosome 14 uniparental disomy. 
  • ErbB2 activity is required for airway epithelial repair following neutrophil elastase exposure. 
  • Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. 
  • Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution. 
  • Essential amino acid deprivation induces monocytic differentiation of the human HL-60 myeloid leukemia cell line. 
  • Estrogen induction of ovalbumin mRNA: evidence for transcription control. 
  • Eukaryotic gene transcription with purified components. 
  • Evaluation of the fiber-optic antibody-based fluoroimmunosensor for DNA adducts in human placenta samples. 
  • Evidence for direct local effect of angiotensin in vascular hypertrophy. In vivo gene transfer of angiotensin converting enzyme. 
  • Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins. 
  • Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. 
  • Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000. 
  • Evidence that methylation of the FMR-I locus is responsible for variable phenotypic expression of the fragile X syndrome. 
  • Evolution of a complex eukaryotic gene. 
  • Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes. 
  • Evolutionary mechanisms for eucaryotic genes. 
  • Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons. 
  • Exclusion of maternal uniparental disomy of chromosome 14 in patients referred for Prader-Willi syndrome using a multiplex methylation polymerase chain reaction assay. 
  • Exome Sequence Analysis of 14 Families With High Myopia. 
  • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 
  • Exon skipping in purine nucleoside phosphorylase mRNA processing leading to severe immunodeficiency. 
  • Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine. 
  • Experimental determination of rates of concerted evolution. 
  • Exposure of cultured murine peritoneal macrophages to low concentrations of beryllium induces increases in intracellular calcium concentrations and stimulates DNA synthesis. 
  • Exposure of mice to topical bovine thrombin induces systemic autoimmunity. 
  • Exposure to hyperoxia induces p53 expression in mouse lung epithelium. 
  • Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region. 
  • Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction. 
  • Expression of O6-methylguanine-DNA methyltransferase in malignant human glioma cell lines. 
  • Expression of RNAs for calmodulin, actins, and tubulins in rat testis cells. 
  • Expression of a highly conserved anti-DNA idiotype in normal and autoimmune mice. 
  • Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors. 
  • Expression of active, membrane-bound human placental alkaline phosphatase by transfected simian cells. 
  • Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance. 
  • Expression of human protein phosphatase-1 in Saccharomyces cerevisiae highlights the role of phosphatase isoforms in regulating eukaryotic functions. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth. 
  • Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection. 
  • Extending the range of microsecond-to-millisecond chemical exchange detected in labeled and unlabeled nucleic acids by selective carbon R(1rho) NMR spectroscopy. 
  • Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR. 
  • Extracellular potassium influences DNA and protein syntheses and glial fibrillary acidic protein expression in cultured glial cells. 
  • FACS-optimized mutants of the green fluorescent protein (GFP). 
  • FGF12 is a candidate Brugada syndrome locus. 
  • Fabrication of layer-by-layer deposited multilayer films containing DNA and its interaction with methyl green. 
  • Facial pain with localized and widespread manifestations: separate pathways of vulnerability. 
  • Factors regulating islet regeneration in the post-insulinoma NEDH rat. 
  • Failure of the ILD to determine data combinability for slow loris phylogeny. 
  • Familial X-linked myalgia and cramps: a nonprogressive myopathy associated with a deletion in the dystrophin gene. 
  • Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001. 
  • Female steroid hormones and target cell nuclei. 
  • Fetal dexamethasone exposure alters macromolecular characteristics of rat brain development: a critical period for regionally selective alterations? 
  • Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: effects on DNA and protein in whole tissues. 
  • Fetal dexamethasone exposure sensitizes neonatal rat brain to hypoxia: effects on protein and DNA synthesis. 
  • Fiber autoradiography of replicating yeast DNA. 
  • Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. 
  • Field distribution and DNA transport in solid tumors during electric field-mediated gene delivery. 
  • Field- and phage-induced dipolar couplings in a homodimeric DNA quadruplex: relative orientation of G.(C-A) triad and G-tetrad motifs and direct determination of C2 symmetry axis orientation. 
  • Fine mapping of a putative rd cDNA and its co-segregation with rd expression. 
  • Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. 
  • Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence. 
  • Finite-size, fully addressable DNA tile lattices formed by hierarchical assembly procedures. 
  • Flexible histone tails in a new mesoscopic oligonucleosome model. 
  • Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation. 
  • Flow cytometric analysis of DNA content in budding yeast. 
  • Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation. 
  • Flow perfusion maintains ex vivo bone viability: a novel model for bone biology research. 
  • Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery. 
  • Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. 
  • Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. 
  • Formation and repair of 1,3-bis-(2-chloroethyl)-1-nitrosourea and cisplatin induced total genomic DNA interstrand crosslinks in human glioma cells. 
  • Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice. 
  • Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts. 
  • Fragments of ATM which have dominant-negative or complementing activity. 
  • From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms. 
  • From the Cover: mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events. 
  • Full-electron calculation of effective electronic couplings and excitation energies of charge transfer states: Application to hole transfer in DNA pi-stacks. 
  • Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes. 
  • Functional alterations of macrophages in autoimmune MRL-lpr/lpr mice. 
  • Functional analysis of a complementary DNA for the 50-kilodalton subunit of calmodulin kinase II. 
  • Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. 
  • Functional expression of a MAP kinase kinase in COS cells and recognition by an anti-STE7/byr1 antibody. 
  • Functional heterogeneity of mammalian TATA-box sequences revealed by interaction with a cell-specific enhancer. 
  • Functional high efficiency expression of cloned leukocyte chemoattractant receptor cDNAs. 
  • Functional nanostructures from surface chemistry patterning. 
  • Functional specialization of beta-arrestin interactions revealed by proteomic analysis. 
  • Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo. 
  • G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions. 
  • GC sequence specific recognition by an N-formamido, C-terminus-modified and imidazole-containing analogue of netropsin. 
  • Gamma-radiation sensitivity and risk of glioma. 
  • Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. 
  • Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. 
  • Gene expression signatures that predict radiation exposure in mice and humans. 
  • Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis. 
  • Gene transfer and expression in rat cardiac transplants. 
  • Genetic and hormonal sensitivity to threat: testing a serotonin transporter genotype × testosterone interaction. 
  • Genetic and mutational analyses of a large multiethnic Bardet-Biedl cohort reveal a minor involvement of BBS6 and delineate the critical intervals of other loci. 
  • Genetic approaches for the investigation of genes associated with coronary heart disease. 
  • Genetic changes in human adrenocortical carcinomas. 
  • Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. 
  • Genetic diversity does not explain variation in extra-pair paternity in multiple populations of a songbird. 
  • Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. 
  • Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population. 
  • Genetic heterogeneity in MCAD deficiency: frequency of K329E allele and identification of three additional mutant alleles. 
  • Genetic mutations in African patients with atrial fibrillation: Rationale and design of the Study of Genetics of Atrial Fibrillation in an African Population (SIGNAL). 
  • Genetic selection for constitutively trimerized human HSF1 mutants identifies a role for coiled-coil motifs in DNA binding. 
  • Genetic studies in autistic disorder and chromosome 15. 
  • Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1. 
  • Genetic variants associated with severe retinopathy of prematurity in extremely low birth weight infants. 
  • Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis. 
  • Genetically engineered calmodulins differentially activate target enzymes. 
  • Genome organization and three kinds of heritable changes: general description and stochastic factors (a review). 
  • Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. 
  • Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery. 
  • Genome-wide association study of smoking behaviours in patients with COPD. 
  • Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. 
  • Genome-wide localization of replication factors. 
  • Genome-wide scan reveals signatures of selection related to pollution adaptation in non-model estuarine Atlantic killifish (Fundulus heteroclitus). 
  • Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators. 
  • Genomic amplification with transcript sequencing. 
  • Genomic and epigenetic evidence for oxytocin receptor deficiency in autism. 
  • Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex. 
  • Genomic heat shock element sequences drive cooperative human heat shock factor 1 DNA binding and selectivity. 
  • Genomic organization of rat rDNA. 
  • Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. 
  • Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice. 
  • Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution. 
  • Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein. 
  • Glucose metabolism gene variants modulate the risk of pancreatic cancer. 
  • Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4. 
  • Glutathione activates virulence gene expression of an intracellular pathogen. 
  • Group II introns designed to insert into therapeutically relevant DNA target sites in human cells. 
  • Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast. 
  • Guanine to inosine substitution leads to large increases in the population of a transient G·C Hoogsteen base pair. 
  • HL-A antigenic loss in malignant transformation. 
  • HLA-C disparity between patients and unrelated donors matched for HLA-A, -B, and -DRB1 alleles: impact of serological vs. DNA typing for HLA-A and -B loci. 
  • HMGB1 and microparticles as mediators of the immune response to cell death. 
  • Hacking DNA copy number for circuit engineering. 
  • Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration. 
  • Heat-shock protein-70 genes and response to antidepressants in major depression. 
  • Hemoglobin sickle-Lepore: report of two siblings and review of the literature. 
  • Hepatitis B core antibody positive donors as a safe and effective therapeutic option to increase available organs for lung transplantation. 
  • Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8. 
  • Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein. 
  • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. 
  • High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies. 
  • Highly active zinc-finger nucleases by extended modular assembly. 
  • Histologic, nuclear DNA, and human papillomavirus studies of cervical condylomas. 
  • Histone H1 enhances the DNA binding activity of the transcription factor EmBP-1. 
  • Histones of rat testis chromatin during early postnatal development and their interactions with DNA. 
  • Hormonal control of oviduct growth and differentiation. 
  • Human IgE synthesis in vitro: a reassessment. 
  • Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA. 
  • Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products. 
  • Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. 
  • Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. 
  • Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. 
  • Hyalocytes synthesize and secrete inhibitors of retinal pigment epithelial cell proliferation in vitro. 
  • Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery. 
  • Hybridoma SLE autoantibodies: insights for the pathogenesis of autoimmune disease. 
  • Hydrogel-nanoparticle composites for optically modulated cancer therapeutic delivery. 
  • Hydrolysis of template and newly synthesized deoxyribonucleic acid by the 3' to 5' exonuclease activity of the T4 deoxyribonucleic acid polymerase. 
  • Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity. 
  • Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. 
  • Hypoxia impedes the formation of chromium DNA-adducts in a cell-free system. 
  • Identification and analysis of eukaryotic promoters: recent computational approaches. 
  • Identification and cell type specificity of the tyrosine hydroxylase gene promoter. 
  • Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450. 
  • Identification and sequence of the initiation site for rat 45S ribosomal RNA synthesis. 
  • Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing. 
  • Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor. 
  • Identification of a deletion in the adenosine deaminase gene in a child with severe combined immunodeficiency. 
  • Identification of a nonsense mutation at codon 128 of the Norrie's disease gene in a male infant. 
  • Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2. 
  • Identification of a putative second T-cell receptor. 
  • Identification of a rat glomerular mesangial cell mitogenic 5-HT2A receptor. 
  • Identification of a third autonomous activation domain within the human estrogen receptor. 
  • Identification of an alternate promoter in the rat androgen-binding protein/sex hormone-binding globulin gene that regulates synthesis of a messenger RNA encoding a protein with altered function. 
  • Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. I. High resolution epitope mapping and characterization of monoclonal antibody binding sites. 
  • Identification of liver cancer-specific aptamers using whole live cells. 
  • Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA. 
  • Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands. 
  • Identification of putative human T cell receptor delta complementary DNA clones. 
  • Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains. 
  • Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. 
  • Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets. 
  • Identification, characterization, and molecular cloning of a novel transporter-like protein localized to the central nervous system. 
  • Identification, characterization, and ontogeny of a second cytochrome P450 3A gene from the fresh water teleost medaka (Oryzias latipes). 
  • Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. 
  • IgG antibodies from patients with bullous pemphigoid bind to localized epitopes on synthetic peptides encoded by bullous pemphigoid antigen cDNA. 
  • IgG antinuclear antibodies with cross-reactive rheumatoid factor activity. 
  • Imaging molecular pathways: reporter genes. 
  • Immediate decline in DNA synthesis in neonatal rat lung caused by exposure to 100% oxygen. 
  • Immune recognition of DNA in SLE. 
  • Immune responses to DNA in normal and aberrant immunity. 
  • Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit. 
  • Immunologic consequences of acute ethanol ingestion in rats. 
  • Immunologic consequences of nucleic acid therapy. 
  • Immunological properties of bacterial DNA. 
  • Impact of CYP2C19 Metabolizer Status on Patients With ACS Treated With Prasugrel Versus Clopidogrel. 
  • Impaired cytoskeletal organization and membrane integrity in lens fibers of a Rho GTPase functional knockout transgenic mouse. 
  • Improvements to the differential display method for gene analysis. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers. 
  • In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: comparison with its murine parent. 
  • In vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazoles. 
  • In vitro characterization of a mutator T4 DNA polymerase. 
  • In vitro chick embryo cell response to strain MC29 avian leukosis virus. 
  • In vitro selection of aptamers from RNA libraries. 
  • In vitro toxicology of fumonisins and the mechanistic implications. 
  • Incorporation of active DNA/cationic polymer polyplexes into hydrogel scaffolds. 
  • Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase. 
  • Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures. 
  • Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes. 
  • Increased expression of fibroblast growth factors in a rabbit skeletal muscle model of exercise conditioning. 
  • Increased skin carcinogenesis in caspase-activated DNase knockout mice. 
  • Increasing occurrences and functional roles for high energy purine-pyrimidine base-pairs in nucleic acids. 
  • Independently derived murine glomerular immune deposit-forming anti-DNA antibodies are encoded by near-identical VH gene sequences. 
  • Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers. 
  • Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA. 
  • Induction of hepatic CYP1A in channel catfish increases binding of 2-aminoanthracene to DNA in vitro and in vivo. 
  • Induction of internucleosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis. 
  • Influence of assay conditions on ELISA determinations of anti-DNA antibodies. 
  • Influence of the extent of hybridization on the hydrodynamic radius of DNA-functionalized gold nanoparticles. 
  • InfoEvolve: moving from data to knowledge using information theory and genetic algorithms. 
  • Informative priors based on transcription factor structural class improve de novo motif discovery. 
  • Inhibition of DNA binding by differential sumoylation of heat shock factors. 
  • Inhibition of DNA synthesis in neonatal rat brain regions caused by acute nicotine administration. 
  • Inhibition of NF-kappa B by S-nitrosylation. 
  • Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. 
  • Inhibition of in vitro NZB antibody responses by cyclosporine. 
  • Inhibition of in vitro anti-DNA B-cell responses by cyclosporine. 
  • Inhibition of murine macrophage IL-12 production by natural and synthetic DNA. 
  • Inhibition of murine macrophage nitric oxide production by synthetic oligonucleotides. 
  • Inkless microcontact printing on SAMs of Boc- and TBS-protected thiols. 
  • Insights into Watson-Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m1A. 
  • Integrated CMOS microchip system with capillary array electrophoresis. 
  • Integrated genomic analyses in bronchopulmonary dysplasia. 
  • Integrating ambiguously aligned regions of DNA sequences in phylogenetic analyses without violating positional homology. 
  • Integration of cell-free protein coexpression with an enzyme-linked immunosorbent assay enables rapid analysis of protein-protein interactions directly from DNA. 
  • Inter-laboratory comparison of DNA preservation in archival paraffin-embedded human brain tissue from participating centres on four continents. 
  • Interaction of RNA polymerase II with structurally altered nucleosomal particles. Transcription is facilitated by loss of one H2A.H2B dimer. 
  • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. 
  • Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies. 
  • Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene. 
  • Interlaboratory validation of a new assay for DNA-protein crosslinks. 
  • Interleukin-3 expression by activated T cells involves an inducible, T-cell-specific factor and an octamer binding protein. 
  • Interpolated markov chains for eukaryotic promoter recognition. 
  • Interrupter sequences that are widely distributed in the Drosophila genome. 
  • Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4. 
  • Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene. 
  • Intrachromosomal gene conversion and the maintenance of sequence homogeneity among repeated genes. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Intrinsic disorder within and flanking the DNA-binding domains of human transcription factors. 
  • Intrinsic dynamics of DNA-polymer complexes: a mechanism for DNA release. 
  • Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases. 
  • Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles. 
  • Involvement of the S-layer proteins Hpi and SlpA in the maintenance of cell envelope integrity in Deinococcus radiodurans R1. 
  • Ipr gene control of the anti-DNA antibody response. 
  • Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells. 
  • Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. 
  • Is there left-handed DNA at the ends of yeast chromosomes? 
  • Isolated sulfite oxidase deficiency: identification of 12 novel SUOX mutations in 10 patients. 
  • Isolation and analysis of recombinant DNA molecules containing yeast DNA. 
  • Isolation and characterization of a bovine cDNA encoding a functional homolog of human P-selectin. 
  • Isolation and characterization of a human pro alpha 2(I) collagen gene segment. 
  • Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of a novel human prostatic stromal cell culture: DuK50. 
  • Isolation and characterization of cDNAs encoding human brain ankyrins reveal a family of alternatively spliced genes. 
  • Isolation and characterization of the gene encoding rat glucose-dependent insulinotropic peptide. 
  • Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin. 
  • Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins. 
  • Isolation and structural analysis of the chromosomal gene for chicken calmodulin. 
  • Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes. 
  • Isolation of a cDNA clone complementary to sequences for a 34-kilodalton protein which is a pp60v-src substrate. 
  • Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor. 
  • Isolation of a candidate cDNA for the gene causing retinal degeneration in the rd mouse. 
  • Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant. 
  • Isolation of a rat parvalbumin gene and full length cDNA. 
  • Isolation of cDNA clones for basal lamina components: type IV procollagen. 
  • Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily. 
  • Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. 
  • Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification. 
  • JAK2 is required for induction of the murine DUB-1 gene. 
  • Joint learning from multiple types of genomic data. 
  • Joint modeling of DNA sequence and physical properties to improve eukaryotic promoter recognition. 
  • K+ regulates DNA binding of transcription factors to control gene expression related to neuronal apoptosis. 
  • KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes. 
  • Knockdown of prolactin receptors in a pancreatic beta cell line: effects on DNA synthesis, apoptosis, and gene expression. 
  • Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. 
  • Label-free DNA biosensor based on SERS Molecular Sentinel on Nanowave chip. 
  • Lac repressor mRNA transcription terminates in vivo in the lac control region. 
  • Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis. 
  • Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. 
  • Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone. 
  • Laser-induced room-temperature phosphorescence detection of benzo[a]pyrene-DNA adducts. 
  • Learning protein-DNA interaction landscapes by integrating experimental data through computational models. 
  • Left-handed DNA helices, supercoiling, and the B-Z junction. 
  • Leprosy in a mangabey monkey--naturally acquired infection. 
  • Life, diversity and the pursuit of haplotypes. 
  • Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. 
  • Ligation of the alpha2M signaling receptor with receptor-recognized forms of alpha2-macroglobulin initiates protein and DNA synthesis in macrophages. The effect of intracellular calcium. 
  • Linkage analysis for age-related macular degeneration supports a gene on chromosome 10q26. 
  • Linkage analysis in the spinal muscular atrophy type of facioscapulohumeral disease. 
  • Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8. 
  • Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families. 
  • Linkage of Charcot-Marie-Tooth neuropathy type 1a to chromosome 17. 
  • Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse. 
  • Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. 
  • Liposome-mediated conformation transition of DNA detected by molecular probe: methyl green. 
  • Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall. 
  • Localization of a gene (CMT2A) for autosomal dominant Charcot-Marie-Tooth disease type 2 to chromosome 1p and evidence of genetic heterogeneity. 
  • Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. 
  • Localized delivery of DNA to the cells by viral collagen-loaded silica colloidal crystals. 
  • Location of the 5.8S rRNA gene of Saccharomyces cerevisiae. 
  • Locus heterogeneity, anticipation and reduction of the chromosome 2p minimal candidate region in autosomal dominant familial spastic paraplegia. 
  • Long poly(A) tracts in the human genome are associated with the Alu family of repeated elements. 
  • Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood. 
  • Long-range charge transport in single G-quadruplex DNA molecules. 
  • Long-term protein and calorie restriction: alterations in nucleic acid levels of organs of male rats. 
  • Loss of hPot1 function leads to telomere instability and a cut-like phenotype. 
  • Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer. 
  • Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss. 
  • MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. 
  • MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type. 
  • Macromolecular levels, DNA synthesis and ornithine decarboxylase activity in leg muscles from 6-mercaptopurine-treated rats. 
  • Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV. 
  • Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. 
  • Mapping nucleosome positions using DNase-seq. 
  • Maternal vitamin A restriction alters biochemical development of the brain in rats. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • Measurement of DNA adducts using surface-enhanced Raman spectroscopy. 
  • Measurement of mouse T cell receptor excision circles. 
  • Measurement of the DNA synthetic capacity of activated lymphocytes: nucleotide triphosphate incorporation by permeabilized cells. 
  • Mechanism of 5'-directed excision in human mismatch repair. 
  • Mechanisms for the testicular hypertrophy which follows hemicastration. 
  • Mechanisms of DNA-mismatch correction. 
  • Mechanisms of activation of the RAW264.7 macrophage cell line by transfected mammalian DNA. 
  • Mechanisms of anti-DNA antibody expression in normal and aberrant immunity. 
  • Mechanisms of anti-DNA production in human and murine SLE. 
  • Mechanisms of autoantibody production in autoimmune MRL mice. 
  • Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin. 
  • Medium-chain acyl-CoA dehydrogenase deficiency: postmortem diagnosis in a case of sudden infant death and neonatal diagnosis of an affected sibling. 
  • Meiotic mapping of yeast ribosomal deoxyribonucleic acid on chromosome XII. 
  • Meiotic recombination between repeated transposable elements in Saccharomyces cerevisiae. 
  • Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops. 
  • Membrane binding of plasmid DNA and endocytic pathways are involved in electrotransfection of mammalian cells. 
  • MetJ repressor interactions with DNA probed by in-cell NMR. 
  • Metabolism of 1,2-dimethylhydrazine by cultured human colon. 
  • Metabolism of aflatoxin B1, benzo[a]pyrene, and 1,2-dimethylhydrazine by cultured rat and human colon. 
  • Metabolism of benzo[a]pyrene by cultured tracheobronchial tissues from mice, rats, hamsters, bovines and humans. 
  • Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. FUSION (Finland-U.S. Investigation of NIDDM Genetics) Study Group. 
  • Methylation of deoxycytidine incorporated by excision-repair synthesis of DNA. 
  • Methylation of the FSHD syndrome-linked subtelomeric repeat in normal and FSHD cell cultures and tissues. 
  • Methylation-specific PCR. 
  • Microparticles as a source of extracellular DNA. 
  • Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus. 
  • Microparticles as autoadjuvants in the pathogenesis of SLE. 
  • Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus. 
  • Mild cystic fibrosis linked to chromosome 7q22 markers with an uncommon haplotype. 
  • Mismatch repair and genetic stability in human cells. 
  • Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks. 
  • Mismodeled purines: implicit alternates and hidden Hoogsteens. 
  • Missense mutations in the sodium borate cotransporter SLC4A11 cause late-onset Fuchs corneal dystrophy. 
  • Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease. 
  • Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection. 
  • Modeling nuclear molecule release during in vitro cell death. 
  • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. 
  • Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells. 
  • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. 
  • Modular, well-behaved reversible polymers from DNA-based monomers. 
  • Modulation of macrophage colony stimulating factor in cultured human retinal pigment epithelial cells. 
  • Modulation of potassium transport in cultured retinal pigment epithelium and retinal glial cells by serum and epidermal growth factor. 
  • Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes. 
  • Molecular analysis of highly enriched populations of T-cell-depleted monocytes. 
  • Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency. 
  • Molecular analysis of recombination in a family with Duchenne muscular dystrophy and a large pericentric X chromosome inversion. 
  • Molecular analysis of the 60-kDa human Ro ribonucleoprotein. 
  • Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33. 
  • Molecular basis of defective anion transport in L cells expressing recombinant forms of CFTR. 
  • Molecular biology of gastrointestinal peptides and growth factors: relevance to intestinal adaptation. 
  • Molecular characterization of MHC class II antigens (beta 1 domain) in the BB diabetes-prone and -resistant rat. 
  • Molecular characterization of ribosomal genes on the Ybb- chromosome of Drosophila melanogaster. 
  • Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor. 
  • Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype. 
  • Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. 
  • Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. 
  • Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme. 
  • Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA. 
  • Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA. 
  • Molecular cloning of a new human G protein. Evidence for two Gi alpha-like protein families. 
  • Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulus-response coupling. 
  • Molecular cloning of cDNA that encode MHC class I molecules from a New World primate (Saguinus oedipus). Natural selection acts at positions that may affect peptide presentation to T cells. 
  • Molecular cloning of ovomucoid gene sequences from partially purified ovomucoid messenger RNA. 
  • Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP). 
  • Molecular cloning of the cDNA for androgen-dependent sperm-coating glycoproteins secreted by the rat epididymis. 
  • Molecular cloning of the cDNA for ligatin. 
  • Molecular cloning of the cDNA for two major androgen-dependent secretory proteins of 18.5 kilodaltons synthesized by the rat epididymis. 
  • Molecular genetic studies of major histocompatibility complex genes in children with juvenile dermatomyositis: increased risk associated with HLA-DQA1 *0501. 
  • Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein. 
  • Molecular mapping of functional domains of the leukocyte receptor for endothelium, LAM-1. 
  • Molecular measurement of T cell receptor excision circles. 
  • Molecular mechanisms of dominant negative activity by nuclear hormone receptors. 
  • Molecular sentinel-on-chip for SERS-based biosensing. 
  • Molecular signals in B cell activation. II. IL-2-mediated signals are required in late G1 for transition to S phase after ionomycin and PMA treatment. 
  • Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene. 
  • Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase. 
  • Molecular structure of the La and Ro autoantigens and their use in autoimmune diagnostics. 
  • Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. 
  • Morphologic and functional studies of mouse hepatocytes in primary culture. 
  • Morphological and biochemical changes which occur during postnatal development and maturation of the rat testis. 
  • Mosaicism for an FMR1 gene deletion in a fragile X female. 
  • Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis. 
  • Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. 
  • Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways. 
  • Multiple forms of rat liver type I topoisomerase. 
  • Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells. 
  • Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip. 
  • Multivariable analysis of DNA ploidy, p53, and HER-2/neu as prognostic factors in endometrial cancer. 
  • Murine polypyrimidine tract binding protein. Purification, cloning, and mapping of the RNA binding domain. 
  • Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization. 
  • Mutation analysis of the RET receptor tyrosine kinase in Hirschsprung disease. 
  • Mutation analysis of the TSC2 gene in an African-American family. 
  • Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 
  • Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. 
  • Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS). 
  • Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness. 
  • Mutations in acid beta-galactosidase cause GM1-gangliosidosis in American patients. 
  • Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease. 
  • Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes. 
  • Myosin light chain kinase structure function analysis using bacterial expression. 
  • Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene. 
  • NAD+ modulates p53 DNA binding specificity and function. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NF1-related locus on chromosome 15. 
  • NOS2 regulation of NF-kappaB by S-nitrosylation of p65. 
  • Naked DNA delivered intraportally expresses efficiently in hepatocytes. 
  • Nanomechanical fingerprints of UV damage to DNA. 
  • Nanomechanical fingerprints of gamma radiation damage to DNA. 
  • Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements. 
  • Nanoscale detection of ionizing radiation damage to DNA by atomic force microscopy. 
  • Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse. 
  • Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice. 
  • Neuronal control of cardiac and hepatic macromolecule synthesis in the neonatal rat: effects of sympathectomy. 
  • Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart. 
  • Neuronal transfection using particle-mediated gene transfer. 
  • Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. 
  • Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. 
  • New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey. 
  • New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone. 
  • New techniques for DNA sequence classification. 
  • Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos. 
  • Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations. 
  • Nitric oxide synthase 2(Lambaréné) (G-954C), increased nitric oxide production, and protection against malaria. 
  • Nitrosative stress-induced apoptosis through inhibition of NF-kappa B. 
  • No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. 
  • Nonconsensus Protein Binding to Repetitive DNA Sequence Elements Significantly Affects Eukaryotic Genomes. 
  • Noninvasive fetal RhCE genotyping from maternal blood. 
  • Norfloxacin-induced DNA gyrase cleavage complexes block Escherichia coli replication forks, causing double-stranded breaks in vivo. 
  • Notes on Agaricus section Duploannulati using molecular and morphological data. 
  • Novel mutations in the CLN6 gene causing a variant late infantile neuronal ceroid lipofuscinosis. 
  • Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries. 
  • Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. 
  • Nuclear DNA from primate dug 
  • Nuclear inositol signaling: a structural and functional approach. 
  • Nuclease activity in a fragment of bacteriophage T4 deoxyribonucleic acid polymerase induced by the amber mutant am B22. 
  • Nucleic acid binding drugs--XIV. The crystal structure of 1-methyl amsacrine hydrochloride; relationships to DNA-binding ability and anti-tumour activity. 
  • Nucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responses. 
  • Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert. 
  • Nucleosomes influence multiple steps during replication initiation. 
  • Nucleotide sequence of mouse SCIP cDNA, a POU-domain transcription factor. 
  • Nucleotide sequence of the envelope protein genes of a highly virulent, neurotropic strain of Newcastle disease virus. 
  • O-Alkyl dioleoylphosphatidylcholinium compounds: the effect of varying alkyl chain length on their physical properties and in vitro DNA transfection activity. 
  • O6-benzylguanine-mediated enhancement of chemotherapy. 
  • Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase. 
  • OligoCalc: an online oligonucleotide properties calculator. 
  • On the origins, structures and functions of restriction-modification enzymes. 
  • Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling. 
  • One-step and stepwise magnification of a bobbed lethal chromosome in Drosophila melanogaster. 
  • Optical mapping of protein-DNA complexes on chromatin fibers. 
  • Optimal sequence selection in proteins of known structure by simulated evolution. 
  • Optimized lymphocyte protein extraction performed simultaneously with DNA and RNA isolation: application to the study of factors affecting DNA, RNA, and protein recovery from lymphocytes of the oldest individuals. 
  • Optimizing aptamer activity for gene therapy applications using expression cassette SELEX. 
  • Organization of the human zeta-crystallin/quinone reductase gene (CRYZ). 
  • Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene. 
  • Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. 
  • Ovalbumin gene: purification of the coding strand. 
  • Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner. 
  • Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity. 
  • Ovomucoid intervening sequences specify functional domains and generate protein polymorphism. 
  • Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor. 
  • Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. 
  • Oxidative stress activates anion exchange protein 2 and AP-1 in airway epithelial cells. 
  • Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism. 
  • PI3K stimulates DNA synthesis and cell-cycle progression via its p55PIK regulatory subunit interaction with PCNA. 
  • PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: summary of the literature and implications for genetic testing. 
  • PNA versus DNA: effects of structural fluctuations on electronic structure and hole-transport mechanisms. 
  • Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. 
  • Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo. 
  • Parallel molecular computations of pairwise exclusive-or (XOR) using DNA "string tile" self-assembly. 
  • Peptide elongation factor eEF1A-2/S1 expression in cultured differentiated myotubes and its protective effect against caspase-3-mediated apoptosis. 
  • Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells. 
  • Perinatal dietary supplementation with a commercial soy lecithin preparation: effects on behavior and brain biochemistry in the developing rat. 
  • Perinatal environmental tobacco smoke exposure in rhesus monkeys: critical periods and regional selectivity for effects on brain cell development and lipid peroxidation. 
  • Peroxide-mediated chromatin remodelling of a nuclear factor kappa B site in the mouse inducible nitric oxide synthase promoter. 
  • Personal DNA testing in college classrooms: perspectives of students and professors. 
  • Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning. 
  • Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity. 
  • Photocontrolled micellar aggregation of amphiphilic DNA-azobenzene conjugates. 
  • Photoselected electron transfer pathways in DNA photolyase. 
  • Phylogenetic relationships, morphological incongruence, and geographic speciation in the fontinalaceae (Bryophyta). 
  • Phylogenomic analyses data of the avian phylogenomics project. 
  • Physical and biological properties of cationic triesters of phosphatidylcholine. 
  • Physiologic role for enhanced renal thromboxane production in murine lupus nephritis. 
  • Physiological and molecular basis of thyroid hormone action. 
  • Plasmids for recombination-based screening. 
  • Plasmonic SERS biosensing nanochips for DNA detection. 
  • Plasmonic coupling interference (PCI) nanoprobes for nucleic acid detection. 
  • Plasmonic nanoprobes for SERS biosensing and bioimaging. 
  • Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy. 
  • Plasmonics nanoprobes: detection of single-nucleotide polymorphisms in the breast cancer BRCA1 gene. 
  • Plasmonics-based SERS nanobiosensor for homogeneous nucleic acid detection. 
  • Plasmonics-based nanostructures for surface-enhanced Raman scattering bioanalysis. 
  • Plasticity in the adult human oligodendrocyte lineage. 
  • Polymorphic repeats in the androgen receptor gene: molecular markers of prostate cancer risk. 
  • Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study. 
  • Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use. 
  • Polymorphisms in BRCA1 and BRCA2 and risk of epithelial ovarian cancer. 
  • Polypeptides of avian RNA tumor viruses. 3. Purification and identification of a DNA synthesizing enzyme. 
  • Polyspecific binding of Escherichia coli beta-galactosidase by murine antibodies to DNA. 
  • Polyspecific reactivity of a murine monoclonal antibody that binds to nuclear matrix-associated, chromatin-bound autoantigens. 
  • Population bottlenecks as a potential major shaping force of human genome architecture. 
  • Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. 
  • Porous hyaluronic acid hydrogels for localized nonviral DNA delivery in a diabetic wound healing model. 
  • Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts. 
  • Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. 
  • Potential for germ line transmission after intramyocardial gene delivery by adeno-associated virus. 
  • Pre-proglucagon messenger ribonucleic acid: nucleotide and encoded amino acid sequences of the rat pancreatic complementary deoxyribonucleic acid. 
  • Precise arrangement of factor-binding sites is required for murine CD4 promoter function. 
  • Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). 
  • Preferential DNA-protein cross-linking by NiCl2 in magnesium-insoluble regions of fractionated Chinese hamster ovary cell chromatin. 
  • Preferential formation and repair of chromium-induced DNA adducts and DNA--protein crosslinks in nuclear matrix DNA. 
  • Preferential synthesis of yeast mitochondrial DNA in alpha factor-arrested cells. 
  • Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus. 
  • Preliminary perspectives on DNA collection in anti-human trafficking efforts. 
  • Prenatal cocaine and cell development in rat brain regions: effects on ornithine decarboxylase and macromolecules. 
  • Prenatal diagnosis and carrier detection for glycogen storage disease type III using polymorphic DNA markers. 
  • Prenatal exclusion of Ehlers-Danlos syndrome type VI by mutational analysis. 
  • Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth. 
  • Prenatal exposure to propranolol via continuous maternal infusion: effects on physiological and biochemical processes mediated by beta adrenergic receptors in fetal and neonatal rat lung. 
  • Preparation of 5-[131I]iodo- and 5-[211At]astato-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil by a halodestannylation reaction. 
  • Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR. 
  • Presence of large deletions in kindreds with autism. 
  • Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy. 
  • Prevention of H2O2 generation by monoamine oxidase protects against CNS O2 toxicity. 
  • Priming with plasmid DNAs expressing interleukin-12 and simian immunodeficiency virus gag enhances the immunogenicity and efficacy of an experimental AIDS vaccine based on recombinant vesicular stomatitis virus. 
  • Probabilistic Analysis of Localized DNA Hybridization Circuits. 
  • Probing sequence-specific DNA flexibility in a-tracts and pyrimidine-purine steps by nuclear magnetic resonance (13)C relaxation and molecular dynamics simulations. 
  • Probing transient Hoogsteen hydrogen bonds in canonical duplex DNA using NMR relaxation dispersion and single-atom substitution. 
  • Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. 
  • Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes. 
  • Programmable DNA self-assemblies for nanoscale organization of ligands and proteins. 
  • Programmed cell death induced by ceramide. 
  • Prokaryotic transcription regulators: more than just the helix-turn-helix motif. 
  • Proliferation of Double-Strand Break-Resistant Polyploid Cells Requires Drosophila FANCD2. 
  • Promoter hypermethylation profile of kidney cancer. 
  • Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination. 
  • Properties of overlapping genes are conserved across microbial genomes 
  • Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling. 
  • Prospects for personalized cardiovascular medicine: the impact of genomics. 
  • Prostaglandin F2 alpha-induced mitogenesis in MC3T3-E1 osteoblasts: role of protein kinase-C-mediated tyrosine phosphorylation. 
  • Protein phosphatase 5 is required for ATR-mediated checkpoint activation. 
  • Protein-DNA binding in the absence of specific base-pair recognition. 
  • Protein-DNA binding: complexities and multi-protein codes. 
  • Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex. 
  • Pulling geometry-induced errors in single molecule force spectroscopy measurements. 
  • Pulmonary fibrogenesis after three consecutive inhalation exposures to chrysotile asbestos. 
  • Pulse Field Gel Electrophoresis. 
  • Pulsed-field gel electrophoresis. 
  • Putative telomere-recruiting domain in the catalytic subunit of human telomerase. 
  • Quality of DNA extracted from mouthwashes. 
  • Quantification of normal cell death in the rat retina: implications for clone composition in cell lineage analysis. 
  • Quantitative DNA pooling to increase the efficiency of linkage analysis in autosomal dominant disease. 
  • Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. 
  • Quantitative modeling of transcription factor binding specificities using DNA shape. 
  • Quenching of DNA cross-link precursors of chloroethylnitrosoureas and attenuation of DNA interstrand cross-linking by glutathione. 
  • RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue. 
  • RNA transfected dendritic cells as cancer vaccines. 
  • RNA-transfected dendritic cells in cancer immunotherapy. 
  • RNA∶DNA hybrids initiate quasi-palindrome-associated mutations in highly transcribed yeast DNA. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Rabbits immunized with a peptide encoded for by the 230-kD bullous pemphigoid antigen cDNA develop an enhanced inflammatory response to UVB irradiation: a potential animal model for bullous pemphigoid. 
  • Randomised trial of plasma exchange in mild systemic lupus erythematosus. 
  • Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. 
  • Rapid DNA sequencing of more than 1000 bases per run by capillary electrophoresis using replaceable linear polyacrylamide solutions. 
  • Rapid analysis of small nucleic acid samples by gel electrophoresis. 
  • Rapid communication: BamHI restriction fragment length polymorphism detected with a pig gastric mucin (MUC5AC) probe. 
  • Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. 
  • Rapid evolution of cis-regulatory sequences via local point mutations. 
  • Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites. 
  • Rat amylin: cloning and tissue-specific expression in pancreatic islets. 
  • Rat granulosa cells express transforming growth factor-beta type 2 messenger ribonucleic acid which is regulatable by follicle-stimulating hormone in vitro. 
  • Receptor binding, endocytosis, and mitogenesis of insulin-like growth factors I and II in fetal rat brain neurons. 
  • Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems. 
  • Recombinant human interleukin 1 alpha: purification and biological characterization. 
  • Recombination of 4p16 DNA markers in an unusual family with Huntington disease. 
  • Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity. 
  • Recommendations for national and local regulatory authorities concerning research in genetic markers of disease. 
  • Reconfigurable core-satellite nanoassemblies as molecularly-driven plasmonic switches. 
  • Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. 
  • Reduction of folic acid-induced acute tubular injury by diuresis: an experimental model. 
  • Reduction of intimal hyperplasia and enhanced reactivity of experimental vein bypass grafts with verapamil treatment. 
  • Refinement of map position of the human GluR6 kainate receptor gene (GRIK2) and lack of association and linkage with idiopathic generalized epilepsies. 
  • Regulation of Clara cell secretory protein gene transcription by thyroid transcription factor-1. 
  • Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. 
  • Regulation of Sertoli cell function and differentiation through the actions of a testicular paracrine factor P-Mod-S. 
  • Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene. 
  • Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I. 
  • Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. 
  • Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. 
  • Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. 
  • Regulation of the human interleukin-3 gene. 
  • Regulation of tyrosine hydroxylase mRNA by glucocorticoid and cyclic AMP in a rat pheochromocytoma cell line. Isolation of a cDNA clone for tyrosine hydroxylase mRNA. 
  • Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells. 
  • Regulatory and structural motifs of chicken gizzard myosin light chain kinase. 
  • Relationship between adipose stromal-vascular cells and adipocytes in human adipose tissue. 
  • Relationships among DNA sequences of the 1.3 kb EcoRI family of mouse DNA. 
  • Relative promoter activity in human mammary epithelial cells assayed by transient expression. 
  • Relaxin treatment of solid tumors: effects on electric field-mediated gene delivery. 
  • Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus. 
  • Replication of the TCF4 intronic variant in late-onset Fuchs corneal dystrophy and evidence of independence from the FCD2 locus. 
  • Replication of yeast chromosomal DNA. 
  • Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus. 
  • Replication, recombination, and repair: going for the gold. 
  • Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. 
  • Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1. 
  • Restricted expression of WT1 messenger ribonucleic acid in immature ovarian follicles: uniformity in mammalian and avian species and maintenance during reproductive senescence. 
  • Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase. 
  • Retrospective family study of childhood medulloblastoma. 
  • Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer. 
  • Revealing noncovalent interactions. 
  • Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor. 
  • RhoB-dependent modulation of postendocytic traffic in polarized Madin-Darby canine kidney cells. 
  • Ribozyme-mediated revision of RNA and DNA. 
  • Robust IR-based detection of stable and fractionally populated G-C+ and A-T Hoogsteen base pairs in duplex DNA. 
  • Role for topoisomerase 1 in transcription-associated mutagenesis in yeast. 
  • Role of macrophages in the generation of circulating blood nucleosomes from dead and dying cells. 
  • Roles of 3,5,3'-triiodothyronine and deoxyribonucleic acid binding on thyroid hormone receptor complex formation. 
  • Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. 
  • SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. 
  • SOS induction as an in vivo assay of enzyme-DNA interactions. 
  • Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial. 
  • Satellite DNA sequences of Drosophila melanogaster. 
  • Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants. 
  • Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel. 
  • Search for genes involved in Joubert syndrome: evidence that one or more major loci are yet to be identified and exclusion of candidate genes EN1, EN2, FGF8, and BARHL1. 
  • Sedimentation properties of yeast chromosomal DNA. 
  • Selective inhibition of Alu retrotransposition by APOBEC3G. 
  • Selective recognition of DNA antigenic determinants by murine monoclonal anti-DNA antibodies. 
  • Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles. 
  • Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. 
  • Separating DNA with different topologies by atomic force microscopy in comparison with gel electrophoresis. 
  • Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage. 
  • Sequence complexity of nuclear RNAs in adult rat tissues. 
  • Sequence features of DNA binding sites reveal structural class of associated transcription factor. 
  • Sequence of full length cDNA for human S-adenosylhomocysteine hydrolase. 
  • Sequence of the cDNA for the alpha subunit of calmodulin kinase II from mouse brain. 
  • Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. 
  • Sequence-specific B-DNA flexibility modulates Z-DNA formation. 
  • Sequencing and analysis of genomic fragments from the NF1 locus. 
  • Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix. 
  • Serotonin transporter gene polymorphism and antidepressant response. 
  • Serum immunoglobulin levels in systemic lupus erythematosus: the effects of age, sex, race and disease duration. 
  • Serum withdrawal induces apoptotic cell death in Ki-ras transformed but not in normal differentiated thyroid cells. 
  • Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz. 
  • Signatures of protein-DNA recognition in free DNA binding sites. 
  • Silver impairs neurodevelopment: studies in PC12 cells. 
  • Simple Mendelian inheritance of the reiterated ribosomal DNA of yeast. 
  • Single molecule mechanical manipulation for studying biological properties of proteins, DNA, and sugars. 
  • Single- and dual-fractal analysis of hybridization binding kinetics: biosensor applications. 
  • Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α. 
  • Size and structure of yeast chromosomal DNA. 
  • Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase. 
  • SnapShot: Origins of DNA replication. 
  • Snapshot of the allele-specific variation in human gene expression. 
  • Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla. 
  • Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. 
  • Solution structure of the core NFATC1/DNA complex. 
  • Somatic mutation of TRbeta can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor. 
  • Somatic uniparental disomy of Chromosome 16p in hemimegalencephaly. 
  • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. 
  • Specificity analysis of monoclonal anti-DNA antibodies. 
  • Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity. 
  • Specificity and immunochemical properties of anti-DNA antibodies induced in normal mice by immunization with mammalian DNA with a CpG oligonucleotide as adjuvant. 
  • Specificity and immunochemical properties of antibodies to bacterial DNA. 
  • Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. 
  • Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage. 
  • Spontaneous expression of antibodies to DNA of various species origin in sera of normal subjects and patients with systemic lupus erythematosus. 
  • Stability selection for regression-based models of transcription factor-DNA binding specificity. 
  • Standardization of anti-DNA antibody assays. 
  • Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. 
  • Statistics for ChIP-chip and DNase hypersensitivity experiments on NimbleGen arrays. 
  • Stepwise self-assembly of DNA tile lattices using dsDNA bridges. 
  • Stimulation of DNA synthesis in human epidermis by UVB radiation and its inhibition by difluoromethylornithine. 
  • Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. 
  • Stress and death: breaking up the c-Abl/14-3-3 complex in apoptosis. 
  • Stretching single molecules into novel conformations using the atomic force microscope. 
  • Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectin. 
  • Structural and functional domains of the Drosophila ncd microtubule motor protein. 
  • Structural and immunological comparison of indigenous human O6-methylguanine-DNA methyltransferase with that encoded by a cloned cDNA. 
  • Structural basis of beta-adrenergic receptor subtype specificity studied with chimeric beta 1/beta 2-adrenergic receptors. 
  • Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase. 
  • Structural mechanisms of QacR induction and multidrug recognition. 
  • Structural organization and chromosomal assignment of the parvalbumin gene. 
  • Structural relationships in glycogen phosphorylases. 
  • Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain. 
  • Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse. 
  • Structure and regulation of the murine Clara cell secretory protein gene. 
  • Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage. 
  • Structure and stability of monomeric lambda repressor: NMR evidence for two-state folding. 
  • Structure of DNA in DNA replication mutants of yeast. 
  • Structure of DNA polymerase I Klenow fragment bound to duplex DNA. 
  • Structure of a G.T.A triplet in an intramolecular DNA triplex. 
  • Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein. 
  • Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy. 
  • Structure of the eukaryotic transcription apparatus: features of the gene for the largest subunit of Drosophila RNA polymerase II. 
  • Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1). 
  • Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils. 
  • Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. 
  • Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. 
  • Structures of mismatch replication errors observed in a DNA polymerase. 
  • Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. 
  • Studies leading to the isolation of a cDNA for the gene causing retinal degeneration in the rd mouse. 
  • Studies of the regulatory mechanism of Ca2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate. 
  • Studies on DNA replication in the bacteriophage T4 in vitro system. 
  • Studies on mode of action of vitamin A. 
  • Study design for genetic analysis in the Jackson Heart Study. 
  • Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. 
  • Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification. 
  • Surface-enhanced Raman scattering plasmonic enhancement using DNA origami-based complex metallic nanostructures. 
  • Surface-tethered DNA complexes for enhanced gene delivery. 
  • Surface-to-surface bridges formed by reversibly assembled polymers. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211. 
  • Sustained release of plasmid DNA using lipid microtubules and agarose hydrogel. 
  • Synaptonemal complex karyotyping in spermatocytes of the Chinese hamster (Cricetulus griseus). III. Quantitative evaluation. 
  • Synergistic enhancement of both initiation and elongation by acidic transcription activation domains. 
  • Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct. 
  • Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase. 
  • Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease. 
  • Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. 
  • Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration. 
  • Systemic lupus erythematosus: a matter of life and death. 
  • T locus shows no evidence for linkage disequilibrium or mutation in American Caucasian neural tube defect families. 
  • T296----M, a common mutation causing mild hemophilia B in the Amish and others: founder effect, variability in factor IX activity assays, and rapid carrier detection. 
  • TFBSshape: a motif database for DNA shape features of transcription factor binding sites. 
  • Targeted expression of calmodulin increases ventricular cardiomyocyte proliferation and deoxyribonucleic acid synthesis during mouse development. 
  • Telomerase activity in normal leukocytes and in hematologic malignancies. 
  • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. 
  • Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation. 
  • The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro. 
  • The Alarmin Properties of DNA and DNA-associated Nuclear Proteins. 
  • The B-cell repertoire for autoantibodies: frequency of precursor cells for anti-DNA antibodies. 
  • The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology. 
  • The DNA binding domain of a papillomavirus E2 protein programs a chimeric nuclease to cleave integrated human papillomavirus DNA in HeLa cervical carcinoma cells. 
  • The DNA-binding homeo domain of the Oct-2 protein. 
  • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. 
  • The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase. 
  • The Krüppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. 
  • The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter. 
  • The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. 
  • The PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial: study rationale, design, and baseline patient characteristics. 
  • The RNAissance period. 
  • The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals. 
  • The Saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties. 
  • The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. 
  • The Top1 paradox: Friend and foe of the eukaryotic genome. 
  • The Use of Poly-L-Lysine as a Capture Agent to Enhance the Detection of Antinuclear Antibodies by ELISA. 
  • The accessible chromatin landscape of the human genome. 
  • The activation domain of the MotA transcription factor from bacteriophage T4. 
  • The alpha 1C-adrenergic receptor: a new member in the alpha 1-adrenergic receptor family. 
  • The androgen-binding protein gene is expressed in CD1 mouse testis. 
  • The anti-La response of a single MRL/Mp-lpr/lpr mouse: specificity for DNA and VH gene usage. 
  • The antigenic properties of bacterial DNA in normal and aberrant immunity. 
  • The apolipoprotein E epsilon2 allele and aging-associated health deterioration in older males. 
  • The binding of sera of patients with SLE to bacterial and mammalian DNA. 
  • The blood nucleome in the pathogenesis of SLE. 
  • The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages. 
  • The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation. 
  • The clinical utility of measuring complement and anti-dsDNA antibodies during pregnancy in patients with systemic lupus erythematosus. 
  • The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. 
  • The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis. 
  • The dopamine transporter. The cloned target site of parkinsonism-inducing toxins and of drugs of abuse. 
  • The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex. 
  • The effect of age on the accumulation of labile triosephosphate isomerase and thymidine incorporation in pokeweed mitogen stimulated human lymphocytes. 
  • The effect of dexamethasone on the generation of plasma DNA from dead and dying cells. 
  • The effect of inflammation on the generation of plasma DNA from dead and dying cells in the peritoneum. 
  • The effect of octreotide on hepatic regeneration in rats. 
  • The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects. 
  • The effect of transforming growth factor-beta on follicle-stimulating hormone-induced differentiation of cultured rat granulosa cells. 
  • The effects of CpG DNA on HMGB1 release by murine macrophage cell lines. 
  • The effects of aging on phosphofructokinase induction during lymphocyte mitogenesis in relation to DNA and protein synthesis. 
  • The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death. 
  • The fine specificity of monoclonal anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. 
  • The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response. 
  • The gamma delta T cell receptor. 
  • The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis. 
  • The generation of extracellular DNA in SLE: the role of death and sex. 
  • The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2. 
  • The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence. 
  • The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells. 
  • The immune response to cell death in SLE. 
  • The immunologic properties of DNA. 
  • The induction of HMGB1 release from RAW 264.7 cells by transfected DNA. 
  • The influence of DNA size on the binding of antibodies to DNA in the sera of normal human subjects and patients with systemic lupus erythematosus (SLE). 
  • The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens. 
  • The influence of base sequence on the immunological properties of defined oligonucleotides. 
  • The influence of base sequence on the immunostimulatory properties of DNA. 
  • The influence of variable-region somatic mutations on the specificity and pathogenicity of murine monoclonal anti-DNA antibodies. 
  • The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers. 
  • The isolation of ecdysterone inducible genes by hybridization subtraction chromatography. 
  • The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus). 
  • The loop domain of heat shock transcription factor 1 dictates DNA-binding specificity and responses to heat stress. 
  • The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 families. 
  • The mechanism of steroid-hormone regulation of transcription of specific eukaryotic genes. 
  • The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. 
  • The moderately repetitive DNA sequences of Caenorhabditis elegans do not show short-period interspersion. 
  • The mouse Cd83 gene: structure, domain organization, and chromosome localization. 
  • The mouse retinoid-X receptor-gamma gene: genomic organization and evidence for functional isoforms. 
  • The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2. 
  • The non-covalent interaction of pyrrolo[2, 1-c] [1, 4]benzodiazepine-5, 11-diones with DNA. 
  • The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. 
  • The origin and properties of extracellular DNA: from PAMP to DAMP. 
  • The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells transfected with human DNA. 
  • The origin of extracellular DNA during the clearance of dead and dying cells. 
  • The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic. 
  • The ovalbumin gene. Partial purification of the coding strand. 
  • The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. 
  • The peripheral myelin protein gene PMP-22 is contained within the Charcot-Marie-Tooth disease type 1A duplication. 
  • The polymorphic locus for glycogen storage disease VI (liver glycogen phosphorylase) maps to chromosome 14. 
  • The potassium channel MBK1 (Kv1.1) is expressed in the mouse retina. 
  • The probability of HLA-C matching between patient and unrelated donor at the molecular level: estimations based on the linkage disequilibrium between DNA typed HLA-B and HLA-C alleles. 
  • The production of transforming growth factor-beta activity by rat granulosa cell cultures. 
  • The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis. 
  • The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis. 
  • The release of DNA into the plasma of mice following hepatic cell death by apoptosis and necrosis. 
  • The role of carbohydrate in the function of human plasminogen: comparison of the protein obtained from molecular cloning and expression in Escherichia coli and COS cells. 
  • The role of cell surface receptors in the activation of human B cells by phosphorothioate oligonucleotides. 
  • The role of extracellular DNA in autoimmunity in SLE. 
  • The role of macrophages in the in vitro generation of extracellular DNA from apoptotic and necrotic cells. 
  • The role of monogamous bivalency and Fc interactions in the binding of anti-DNA antibodies to DNA antigen. 
  • The role of nuclear macromolecules in innate immunity. 
  • The role of ultrasound in women who undergo cell-free DNA screening. 
  • The spliceosome assembly pathway in mammalian extracts. 
  • The structural basis for the mutagenicity of O(6)-methyl-guanine lesions. 
  • The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. 
  • The structural organization of the chicken calmodulin gene. 
  • The use of fluorometric assays to assess the immune response to DNA in murine systemic lupus erythematosus. 
  • Thermal denaturation of DNA from bromodeoxyuridine substituted cells. 
  • Thermodynamics of DNA hybridization on gold nanoparticles. 
  • Thirteen Mhc-DQA1 alleles from two populations of baboons. 
  • Three Pyrimidine Decarboxylations in the Absence of a Catalyst. 
  • Three-helix bundle DNA tiles self-assemble into 2D lattice or 1D templates for silver nanowires. 
  • Thromboxane receptor blockade reduces renal injury in murine lupus nephritis. 
  • Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature. 
  • Thyroid hormone differentially regulates cellular development in neonatal rat heart and kidney. 
  • Tilting at windmills no longer: a data-driven discussion of DTC DNA ancestry tests. 
  • Time and distance dependence of reversible polymer bridging followed by single-molecule force spectroscopy. 
  • Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family. 
  • Tissue-specific expression of the rat androgen-binding protein/sex hormone-binding globulin gene in transgenic mice. 
  • Tissue-specific gene expression in mouse F9 embryonal carcinoma cells: type IV collagen. 
  • Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad. 
  • Topical methotrexate therapy for psoriasis. 
  • Topoisomerase II inhibition and altered kinetics of formation and repair of nitrosourea and cisplatin-induced DNA interstrand cross-links and cytotoxicity in human glioblastoma cells. 
  • Torsional behavior of chromatin is modulated by rotational phasing of nucleosomes. 
  • Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes. 
  • Trans-synaptic increase in RNA coding for tyrosine hydroxylase in a rat sympathetic ganglion. 
  • Transcription as a source of genome instability. 
  • Transcription of H-2 and Qa genes in embryonic and adult mice. 
  • Transcriptional inhibition by carcinogenic chromate: relationship to DNA damage. 
  • Transcriptional regulation of T lymphocyte development and function. 
  • Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin. 
  • Transfection in the third dimension. 
  • Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. 
  • Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element. 
  • Transforming growth factor-beta 1 and mannose 6-phosphate/insulin-like growth factor-II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat. 
  • Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations. 
  • Transient Hoogsteen base pairs in canonical duplex DNA. 
  • Transient expression of a winged-helix protein, MNF-beta, during myogenesis. 
  • Transiently overexpressed alpha2-adrenoceptors and their control of DNA synthesis in the developing brain. 
  • Transrectal gene therapy of the prostate in the canine model. 
  • Transversions have larger regulatory effects than transitions. 
  • Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats. 
  • Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA. 
  • Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide. 
  • Tumor multiplicity, DNA adducts and K-ras mutation pattern of 5-methylchrysene in strain A/J mouse lung. 
  • Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. 
  • Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. 
  • Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein. 
  • Two and three-dimensional gene transfer from enzymatically degradable hydrogel scaffolds. 
  • Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. 
  • Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. 
  • UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y(6) receptors. 
  • UV absorption complicates PCR decontamination. 
  • UVA generates pyrimidine dimers in DNA directly. 
  • Unusual DNA sequences associated with the ends of yeast chromosomes. 
  • Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. 
  • Unusual chromosome architecture and behaviour at an HSR. 
  • Update on the molecular genetics of Duchenne muscular dystrophy. 
  • Use of SYTO 13, a fluorescent dye binding nucleic acids, for the detection of microparticles in in vitro systems. 
  • Use of eukaryotic expression technology in the functional analysis of cloned genes. 
  • Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution. 
  • Using DNA duplex stability information for transcription factor binding site discovery. 
  • Variation in DNA and RNA synthetic responses during activation of lymphocytes from inbred strains of mice. 
  • Variation in the microbiome of the urogenital tract of Chlamydia-free female koalas (Phascolarctos cinereus) with and without 'wet bottom'. 
  • Variations in opsin coding sequences cause x-linked cone dysfunction syndrome with myopia and dichromacy. 
  • Verification of self-report of zygosity determined via DNA testing in a subset of the NAS-NRC twin registry 40 years later. 
  • Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes. 
  • Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein. 
  • Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. 
  • Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. 
  • Widespread transient Hoogsteen base pairs in canonical duplex DNA with variable energetics. 
  • Workshop on cancer biometrics: identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health. 
  • X-linked neuropathy: gene localization with DNA probes. 
  • X-linked severe combined immunodeficiency. Diagnosis in males with sporadic severe combined immunodeficiency and clarification of clinical findings. 
  • Y353/B: a candidate multiple-copy spermiogenesis gene on the mouse Y chromosome. 
  • Yeast chromosomal DNA: size, structure, and replication. 
  • Zinc finger protein binding to DNA: an energy perspective using molecular dynamics simulation and free energy calculations on mutants of both zinc finger domains and their specific DNA bases. 
  • [Quantitative study of the cellular nuclear DNA contents in odontogenic cysts and ameloblastoma]. 
  • beta-Arrestin: a protein that regulates beta-adrenergic receptor function. 
  • beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. 
  • beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. 
  • c-Jun enhancement of cyclic adenosine 3',5'-monophosphate response element-dependent transcription induced by transforming growth factor-beta is independent of c-Jun binding to DNA. 
  • cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase. 
  • cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. 
  • cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product. 
  • cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. 
  • cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. 
  • cis-acting elements that confer lung epithelial cell expression of the CC10 gene. 
  • eNOS, a pressure-dependent regulator of intraocular pressure. 
  • p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. 
• 

  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Allori, Alexander C, Assistant Professor of Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Professor of Pediatrics, in the School of Medicine, Immunology
  • Chen, Jun, Associate Professor of Medicine, Duke Cancer Institute
  • Cianciolo, George James, Associate Professor in Pathology, Pathology
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Gordan, Raluca Mihaela, Assistant Professor in Biostatistics & Bioinformatics, Computer Science
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Kearney, Hutton Moore, Assistant Consulting Professor in the Department of Pathology, Pathology
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology
  • Middleton, John Paul, Associate Professor of Medicine, Medicine, Nephrology
  • Moorman, Patricia Gripka, Professor in Community and Family Medicine, Duke Cancer Institute
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics, Biomedical Engineering
  • Reif, John H., A. Hollis Edens Professor of Computer Science in Trinity College of Arts and Sciences, Electrical and Computer Engineering
  • Schmid, Amy K., Associate Professor of Biology, Duke University Energy Initiative
  • Sullivan, Beth Ann, Associate Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Zhang, Zhiquan, Assistant Professor in Anesthesiology, Anesthesiology