DNA (Cytosine-5-)-Methyltransferase
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Subject Areas on Research
- A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.
- A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer.
- Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia.
- CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity.
- Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine.
- Cutting edge: TGF-beta-induced expression of Foxp3 in T cells is mediated through inactivation of ERK.
- DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs.
- DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes.
- DNA sequences of structural genes for Eco RI DNA restriction and modification enzymes.
- DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions.
- DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset.
- Decreased miRNA-148a is associated with lymph node metastasis and poor clinical outcomes and functions as a suppressor of tumor metastasis in non-small cell lung cancer.
- Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD.
- Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation.
- Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.
- Escherichia coli dam methylase. Physical and catalytic properties of the homogeneous enzyme.
- Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium.
- Genetic variation in the one-carbon transfer pathway and ovarian cancer risk.
- Inhibition of Methicillin-resistant Staphylococcus aureus-induced cytokines mRNA production in human bone marrow derived mesenchymal stem cells by 1,25-dihydroxyvitamin D3.
- Partial NH2- and cooh-terminal sequence analyses of Eco RI DNA restriction and modification enzymes.
- Polymorphisms of the DNMT3B gene and risk of squamous cell carcinoma of the head and neck: a case-control study.
- Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome.
- Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia.
- Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
- Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease.
- Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction.
- Salmonella typhimurium SA host specificity system is based on deoxyribonucleic acid-adenine methylation.
- Site-specific methylases induce the SOS DNA repair response in Escherichia coli.
- Studies on sequence recognition by type II restriction and modification enzymes.
- T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation.
- Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Moorman, Patricia Gripka, Professor in Family Medicine and Community Health, Duke Cancer Institute