DNA, Mitochondrial

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  Subject Areas on Research

  • A colony color method identifies the vulnerability of mitochondria to oxidative damage. 
  • A comparative study of asymmetric migration events across a marine biogeographic boundary. 
  • A haplotype map of the human genome. 
  • A hot-vent gastropod with iron sulfide dermal sclerites. 
  • A multi-locus assessment of connectivity and historical demography in the bluehead wrasse (Thalassoma bifasciatum). 
  • A multi-locus molecular phylogeny of the Lepidoziaceae: laying the foundations for a stable classification. 
  • A new activating role for CO in cardiac mitochondrial biogenesis. 
  • A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS. 
  • A very large Brazilian pedigree with 11778 Leber's hereditary optic neuropathy. 
  • ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation. 
  • Absence of mitochondrial progesterone receptor polymorphisms in women with spontaneous preterm birth. 
  • Acute pancreatitis in an infant with lactic acidosis and a mutation at nucleotide 3243 in the mitochondrial DNA tRNALeu(UUR) gene. 
  • Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance. 
  • Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration. 
  • An allele of HRAS1 3'variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity. 
  • Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR. 
  • Analysis of European mitochondrial haplogroups with Alzheimer disease risk. 
  • Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiae. 
  • Ancient X chromosomes reveal contrasting sex bias in Neolithic and Bronze Age Eurasian migrations. 
  • Ancient co-speciation of simian foamy viruses and primates. 
  • Another surprise from the mitochondrial genome. 
  • Association of mtDNA haplogroup F with healthy longevity in the female Chuang population, China. 
  • Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line. 
  • CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease. 
  • Can three incongruence tests predict when data should be combined? 
  • Canaries in the coal mine: mitochondrial DNA and vascular injury from reactive oxygen species. 
  • Cancer-associated isocitrate dehydrogenase mutations induce mitochondrial DNA instability. 
  • Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans. 
  • Cardiac involvement in mitochondrial diseases, and vice versa. 
  • Chronic cigarette smoke extract treatment selects for apoptotic dysfunction and mitochondrial mutations in minimally transformed oral keratinocytes. 
  • Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction. 
  • Class-level relationships in the phylum Cnidaria: evidence from mitochondrial genome structure. 
  • Class-level relationships in the phylum Cnidaria: molecular and morphological evidence. 
  • Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis. 
  • Comparative toxicity of silver nanoparticles on oxidative stress and DNA damage in the nematode, Caenorhabditis elegans. 
  • Contrasting quaternary histories in an ecologically divergent sister pair of low-dispersing intertidal fish (Xiphister) revealed by multilocus DNA analysis. 
  • Cryptic Patterns of Speciation in Cryptic Primates: Microendemic Mouse Lemurs and the Multispecies Coalescent. 
  • Cryptococcus neoformans mitochondrial genomes from serotype A and D strains do not influence virulence. 
  • Deciding among green plants for whole genome studies. 
  • Defining spatial and temporal patterns of phylogeographic structure in Madagascar's iguanid lizards (genus Oplurus). 
  • Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine. 
  • Delimiting species without nuclear monophyly in Madagascar's mouse lemurs. 
  • Differential expression of mitochondrial DNA replication factors in mammalian tissues. 
  • Differential patterns of male and female mtDNA exchange across the Atlantic Ocean in the blue mussel, Mytilus edulis. 
  • Disentangling the Collema-Leptogium complex through a molecular phylogenetic study of the Collemataceae (Peltigerales, lichen-forming Ascomycota). 
  • Divergence dates for Malagasy lemurs estimated from multiple gene loci: geological and evolutionary context. 
  • Divergent mitochondrial biogenesis responses in human cardiomyopathy. 
  • Diversification before the most recent glaciation in Balanus glandula. 
  • Diversity in the weapons of sexual selection: horn evolution in the beetle genus Onthophagus (Coleoptera: Scarabaeidae). 
  • Dramatic mitochondrial gene rearrangements in the hermit crab Pagurus longicarpus (Crustacea, anomura). 
  • Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans. 
  • Ecological significance of mitochondrial toxicants. 
  • Editor's Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson's Disease Risk. 
  • Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity. 
  • Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. 
  • Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression. 
  • Effects of benzo[a]pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site. 
  • Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans. 
  • Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans. 
  • Effects of selection and mutation on mitochondrial variation and inferences of historical population expansion in a Caribbean reef fish. 
  • Epigenome-wide association study of mitochondrial genome copy number. 
  • Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart. 
  • Evidence against equimolarity of large repeat arrangements and a predominant master circle structure of the mitochondrial genome from a monkeyflower (Mimulus guttatus) lineage with cryptic CMS. 
  • Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson's Disease-Relevant Stress. 
  • Evidence for selection at multiple allozyme loci across a mussel hybrid zone. 
  • Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans. 
  • Expression, purification, and in vitro assays of mitochondrial single-stranded DNA-binding protein. 
  • Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review. 
  • Failure of the ILD to determine data combinability for slow loris phylogeny. 
  • Flow cytometric analysis of DNA content in budding yeast. 
  • Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. 
  • Genes and longevity: lessons from studies of centenarians. 
  • Genes, demography, and life span: the contribution of demographic data in genetic studies on aging and longevity. 
  • Genetic and 'cultural' similarity in wild chimpanzees. 
  • Genetic structure in a dynamic baboon hybrid zone corroborates behavioural observations in a hybrid population. 
  • Genetic variation in the spread of Drosophila subobscura from a nonequilibrium population. 
  • Genetic variation within and among populations of the threatened lichen Lobaria pulmonaria in Switzerland and implications for its conservation. 
  • Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. 
  • Geogenetic patterns in mouse lemurs (genus Microcebus) reveal the ghosts of Madagascar's forests past. 
  • Glutathione regulates susceptibility to oxidant-induced mitochondrial DNA damage in human lymphocytes. 
  • Heme Oxygenase-1/Carbon Monoxide System and Embryonic Stem Cell Differentiation and Maturation into Cardiomyocytes. 
  • Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. 
  • Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. 
  • Host-symbiont stability and fast evolutionary rates in an ant-bacterium association: cospeciation of camponotus species and their endosymbionts, candidatus blochmannia. 
  • Hybrid male sterility in Mimulus (Phrymaceae) is associated with a geographically restricted mitochondrial rearrangement. 
  • Ice-age survival of Atlantic cod: agreement between palaeoecology models and genetics. 
  • Identification of asteroid genera with species capable of larval cloning. 
  • Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy. 
  • Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity. 
  • Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk. 
  • Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis. 
  • Interference of nuclear mitochondrial DNA segments in mitochondrial DNA testing resembles biparental transmission of mitochondrial DNA in humans. 
  • Intraspecific phylogenetic congruence among multiple symbiont genomes. 
  • Involvement of autophagy and mitochondrial dynamics in determining the fate and effects of irreparable mitochondrial DNA damage. 
  • Is congruence between data partitions a reliable predictor of phylogenetic accuracy? Empirically testing an iterative procedure for choosing among phylogenetic methods. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease. 
  • LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction. 
  • Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis. 
  • Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. 
  • Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation. 
  • Maternal lineages and Alzheimer disease risk in the Old Order Amish. 
  • Metabolic capacity regulates iron homeostasis in endothelial cells. 
  • Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM. 
  • Mitochondria as a target of environmental toxicants 
  • Mitochondria in Ovarian Aging and Reproductive Longevity. 
  • Mitochondria in lung biology and pathology: more than just a powerhouse. 
  • Mitochondria in sporadic amyotrophic lateral sclerosis. 
  • Mitochondria, energetics, epigenetics, and cellular responses to stress. 
  • Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation. 
  • Mitochondrial DNA Mutagenesis: Feature of and Biomarker for Environmental Exposures and Aging. 
  • Mitochondrial DNA Sequence Variation Associated With Peripheral Nerve Function in the Elderly. 
  • Mitochondrial DNA alterations in thyroid cancer. 
  • Mitochondrial DNA damage as a peripheral biomarker for mitochondrial toxin exposure in rats. 
  • Mitochondrial DNA damage induced autophagy, cell death, and disease. 
  • Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease. 
  • Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease. 
  • Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration. 
  • Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans. 
  • Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly. 
  • Mitochondrial DNA structure and expression in specialized subtypes of mammalian striated muscle. 
  • Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. 
  • Mitochondrial DNA variation in human metabolic rate and energy expenditure. 
  • Mitochondrial DNA, oxidants, and innate immunity. 
  • Mitochondrial DNA-depleted A549 cells are resistant to bleomycin. 
  • Mitochondrial biogenesis in striated muscles: rapid induction of citrate synthase mRNA by nerve stimulation. 
  • Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans 
  • Mitochondrial dysfunction and insulin resistance: a matter of lifestyle? 
  • Mitochondrial fusion, fission, and mitochondrial toxicity. 
  • Mitochondrial gene expression in mammalian striated muscle. Evidence that variation in gene dosage is the major regulatory event. 
  • Mitochondrial gene rearrangements confirm the parallel evolution of the crab-like form. 
  • Mitochondrial genetic background in Ghanaian patients with primary open-angle glaucoma. 
  • Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. 
  • Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. 
  • Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer. 
  • Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. 
  • Mitochondrial polymorphism A10398G and Haplogroup I are associated with Fuchs' endothelial corneal dystrophy. 
  • Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. 
  • Mitochondrial resequencing arrays detect tumor-specific mutations in salivary rinses of patients with head and neck cancer. 
  • Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. 
  • Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1. 
  • Mobile elements and mitochondrial genome expansion in the soil fungus and potato pathogen Rhizoctonia solani AG-3. 
  • Modelling the effects of age-related mtDNA mutation accumulation; complex I deficiency, superoxide and cell death. 
  • Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees. 
  • Molecular evolutionary dynamics of cytochrome b in strepsirrhine primates: the phylogenetic significance of third-position transversions. 
  • Molecular phylogenetic analysis of the Papionina using concatenation and species tree methods. 
  • Molecular phylogeny of the Entomophthoromycota: 
  • Multiple colonisations of the western Indian Ocean by Pteropus fruit bats (Megachiroptera: Pteropodidae): the furthest islands were colonised first. 
  • Multiple nuclear loci reveal patterns of incomplete lineage sorting and complex species history within western mouse lemurs (Microcebus). 
  • Muscle oxidative capacity during IL-6-dependent cancer cachexia. 
  • Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion. 
  • Nearshore fish (Pholis gunnellus) persists across the North Atlantic through multiple glacial episodes. 
  • New insights into classification and evolution of the Lecanoromycetes (Pezizomycotina, Ascomycota) from phylogenetic analyses of three ribosomal RNA- and two protein-coding genes. 
  • Newly Revised Quantitative PCR-Based Assay for Mitochondrial and Nuclear DNA Damage. 
  • Nitric oxide synthase-2 induction optimizes cardiac mitochondrial biogenesis after endotoxemia. 
  • Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice. 
  • Nonselective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans. 
  • Nonsynonymous somatic mitochondrial mutations occur in the majority of cutaneous melanomas. 
  • Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice. 
  • Nuclear responses to depletion of mitochondrial DNA in human cells. 
  • Obtaining mtDNA genomes from next-generation transcriptome sequencing: a case study on the basal Passerida (Aves: Passeriformes) phylogeny. 
  • Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study. 
  • Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes. 
  • Oxygen-induced mitochondrial biogenesis in the rat hippocampus. 
  • PCR based determination of mitochondrial DNA copy number in multiple species. 
  • PCR-Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage. 
  • PCR-Based Determination of Mitochondrial DNA Copy Number in Multiple Species. 
  • Peripheral Blood Mononuclear Cells Demonstrate Mitochondrial Damage Clearance During Sepsis. 
  • Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals. 
  • Phylogenetic affiliations of members of the heterogeneous lichen-forming fungi of the genus Lecidea sensu Zahlbruckner (Lecanoromycetes, Ascomycota). 
  • Phylogeny and evolution of Malagasy plated lizards. 
  • Phylogeography of a Morphologically Cryptic Golden Mole Assemblage from South-Eastern Africa. 
  • Phylogeography of the arid-adapted Malagasy bullfrog, Laliostoma labrosum, influenced by past connectivity and habitat stability. 
  • Population genetics of a trochid gastropod broadens picture of Caribbean Sea connectivity. 
  • Post-Austronesian migrational wave of West Polynesians to Micronesia. 
  • Postlipopolysaccharide oxidative damage of mitochondrial DNA. 
  • Predictors of mitochondrial DNA copy number and damage in a mercury-exposed rural Peruvian population near artisanal and small-scale gold mining: An exploratory study. 
  • Preferential synthesis of yeast mitochondrial DNA in alpha factor-arrested cells. 
  • Prevalence of mutations in GJB2, SLC26A4, and mtDNA in children with severe or profound sensorineural hearing loss in southwestern China. 
  • Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine purite. 
  • Purifying selection, sequence composition, and context-specific indel mutations shape intraspecific variation in a bacterial endosymbiont. 
  • QPCR: a tool for analysis of mitochondrial and nuclear DNA damage in ecotoxicology. 
  • Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. 
  • Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. 
  • RNA subunit of mitochondrial RNA-processing enzyme is induced by contractile activity in striated muscle. 
  • Rapid mtDNA deletion by oxidants in rat liver mitochondria after hemin exposure. 
  • Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9. 
  • Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment. 
  • Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. 
  • Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle. 
  • Remarkable species diversity in Malagasy mouse lemurs (primates, Microcebus). 
  • Replication and preferential inheritance of hypersuppressive petite mitochondrial DNA. 
  • Reply to Lazaridis and Reich: Robust model-based inference of male-biased admixture during Bronze Age migration from the Pontic-Caspian Steppe. 
  • Resistance of mitochondrial DNA to cadmium and Aflatoxin B1 damage-induced germline mutation accumulation in C. elegans. 
  • Role of mitochondrial DNA damage and dysfunction in veterans with Gulf War Illness. 
  • SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. 
  • SXI1alpha controls uniparental mitochondrial inheritance in Cryptococcus neoformans. 
  • Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria. 
  • Severe Leber Hereditary Optic Neuropathy Plus Disease in a Middle-Aged Man. 
  • Single origin and subsequent diversification of central Andean endemic Umbilicaria species. 
  • Size and structure of yeast chromosomal DNA. 
  • Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. 
  • Social affiliation predicts mitochondrial DNA copy number in female rhesus macaques. 
  • Sources, mechanisms, and consequences of chemical-induced mitochondrial toxicity. 
  • Species delimitation in lemurs: multiple genetic loci reveal low levels of species diversity in the genus Cheirogaleus. 
  • Species discovery and validation in a cryptic radiation of endangered primates: coalescent-based species delimitation in Madagascar's mouse lemurs. 
  • Staphylococcus aureus sepsis and mitochondrial accrual of the 8-oxoguanine DNA glycosylase DNA repair enzyme in mice. 
  • Staphylococcus aureus sepsis induces early renal mitochondrial DNA repair and mitochondrial biogenesis in mice. 
  • Stat3 binds to mtDNA and regulates mitochondrial gene expression in keratinocytes. 
  • Structural insight and characterization of human Twinkle helicase in mitochondrial disease. 
  • Support for a monophyletic Lemuriformes: Overcoming incongruence between data partitions 
  • Temporal Stability of Molecular Diversity Measures in Natural Populations of Drosophila pseudoobscura and Drosophila persimilis. 
  • Testing for contributions of mitochondrial DNA mutations to complex diseases. 
  • The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy. 
  • The HO-1/CO system regulates mitochondrial-capillary density relationships in human skeletal muscle. 
  • The Pleistocene history of the sheepshead minnow (Cyprinodon variegatus): Non-equilibrium evolutionary dynamics within a diversifying species complex. 
  • The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number. 
  • The cantharelloid clade: dealing with incongruent gene trees and phylogenetic reconstruction methods. 
  • The deafness-associated mitochondrial DNA mutation at position 7445, which affects tRNASer(UCN) precursor processing, has long-range effects on NADH dehydrogenase subunit ND6 gene expression. 
  • The ecology and epidemiology of malaria parasitism in wild chimpanzee reservoirs. 
  • The effects of Cenozoic global change on squirrel phylogeny. 
  • The effects of nucleotide substitution model assumptions on estimates of nonparametric bootstrap support. 
  • The high mobility group protein Abf2p influences the level of yeast mitochondrial DNA recombination intermediates in vivo. 
  • The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus). 
  • The mating type-specific homeodomain genes SXI1 alpha and SXI2a coordinately control uniparental mitochondrial inheritance in Cryptococcus neoformans. 
  • The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. 
  • The quick and the dead: microbial demography at the yeast thermal limit. 
  • The rate of mitochondrial mutagenesis is faster in mice than humans. 
  • The role of cytoplasmic deoxycytidine kinase in the mitochondrial effects of the anti-human immunodeficiency virus compound, 2',3'-dideoxycytidine. 
  • The socio-genetics of a complex society: female gelada relatedness patterns mirror association patterns in a multilevel society. 
  • The spatial scale of genetic subdivision in populations of Ifremeria nautilei, a hydrothermal-vent gastropod from the southwest Pacific. 
  • The ties that bind: genetic relatedness predicts the fission and fusion of social groups in wild African elephants. 
  • The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans. 
  • There is substantial agreement among interspecies estimates of DNA repair activity. 
  • Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli. 
  • Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences. 
  • Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism. 
  • UVC-induced mitochondrial degradation via autophagy correlates with mtDNA damage removal in primary human fibroblasts. 
  • Unexpected link between mitochondrial DNA and T cell help in systemic lupus erythematosus. 
  • Uniparental mitochondrial transmission in sexual crosses in Cryptococcus neoformans. 
  • Unusual presentation of Kearns-Sayre syndrome in early childhood. 
  • Using secondary structure to identify ribosomal numts: cautionary examples from the human genome. 
  • Variation in modes and rates of evolution in nuclear and mitochondrial ribosomal DNA in the mushroom genus Amanita (Agaricales, Basidiomycota): phylogenetic implications. 
  • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. 
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  Keywords of People

  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Roth, V. Louise, Professor of Biology, Evolutionary Anthropology