DNA, Satellite

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  Subject Areas on Research

  • A mutation of the yeast gene encoding PCNA destabilizes both microsatellite and minisatellite DNA sequences. 
  • Alpha satellite DNA biology: finding function in the recesses of the genome. 
  • Analysis of Drosophila melanogaster satellite IV with restriction endonuclease MboII. 
  • Analytical DNA fingerprinting in lions: parentage, genetic diversity, and kinship. 
  • Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment. 
  • Blepharophimosis syndrome is linked to chromosome 3q. 
  • Centromeres of human chromosomes. 
  • Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA. 
  • Cytological evidence of transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. 
  • Demographic study of a wild house sparrow population by DNA fingerprinting. 
  • Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. 
  • Development of a microsatellite genetic map spanning 5q31-q33 and subsequent placement of the LGMD1A locus between D5S178 and IL9. 
  • Distal nephron renal tumors: microsatellite allelotype. 
  • Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability. 
  • Elevated frequency of microsatellite mutations in TK6 human lymphoblast clones selected for mutations at the thymidine kinase locus. 
  • Evidence for structural heterogeneity from molecular cytogenetic analysis of dicentric Robertsonian translocations. 
  • Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. 
  • Genetic instability of microsatellites in endometrial carcinoma. 
  • Genetic mapping of dinucleotide repeat polymorphisms and von Hippel-Lindau disease on chromosome 3p25-26. 
  • Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells. 
  • Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles. 
  • Histone gene clusters of the newt notophthalmus are separated by long tracts of satellite DNA. 
  • Human Centromeres Produce Chromosome-Specific and Array-Specific Alpha Satellite Transcripts that Are Complexed with CENP-A and CENP-C. 
  • Human centromere repositioning within euchromatin after partial chromosome deletion. 
  • Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. 
  • Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. 
  • Identification and mapping of type 1 neurofibromatosis (NF1) homologous loci. 
  • Improved genetic fingerprinting using RNA probes. 
  • Instability of simple sequence repeats in a mammalian cell line. 
  • Linkage of Tunisian autosomal recessive Duchenne-like muscular dystrophy to the pericentromeric region of chromosome 13q. 
  • Microsatellite analysis of childhood brain tumors. 
  • Microsatellite instability in gynecological sarcomas and in hMSH2 mutant uterine sarcoma cell lines defective in mismatch repair activity. 
  • Mismatch repair deficiency in phenotypically normal human cells. 
  • Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. 
  • North Carolina macular dystrophy: exclusion map using RFLPs and microsatellites. 
  • Probable exclusion of GLC1A as a candidate glaucoma gene in a family with middle-age-onset primary open-angle glaucoma. 
  • Satellite DNA is transcribed on lampbrush chromosomes. 
  • Structural and functional dynamics of human centromeric chromatin. 
  • Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. 
  • Telomere-to-telomere assembly of a complete human X chromosome. 
  • The evolutionary dynamics of alpha-satellite. 
  • The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure. 
  • α satellite DNA variation and function of the human centromere. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Sullivan, Beth Ann, Professor of Molecular Genetics and Microbiology, Duke Science & Society
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology