Dose-Response Relationship, Immunologic
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Subject Areas on Research
- A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques.
- Activation of human B lymphocytes. III. Concanavalin A-induced generation of suppressor cells of the plaque-forming cell response of normal human B lymphocytes.
- Active specific immunotherapy of Dukes B2 and C colorectal carcinoma: comparison of two doses of the vaccine.
- Alterations in antibody-dependent cellular cytotoxicity during the course of HIV-1 infection. Humoral and cellular defects.
- Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.
- Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice.
- Anti-receptor antibody-induced H-Y-specific delayed-type hypersensitivity responses in nonresponder mice.
- Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.
- Antibodies reactive with class II antigens encoded for by the major histocompatibility complex inhibit human B cell activation.
- Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy.
- B lymphocytes differentially influence acute and chronic allograft rejection in mice.
- Bacterial infection of osteoblasts induces interleukin-1beta and interleukin-18 transcription but not protein synthesis.
- CAMPATH-1H in rheumatoid arthritis--an intravenous dose-ranging study.
- CD4+Thy1- thymocytes with a Th-type 2 cytokine response.
- Characterization of human chemotactic lymphokine production induced by mitogens and mixed leukocyte reactions using a new microassay.
- Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with non-replicating antigens.
- Comparison of multiple vaccine vectors in a single heterologous prime-boost trial.
- Control of idiotope expression by monoclonal anti-idiotope and idiotope-bearing antibody.
- Corneal organ cultures in tyrosinemia release chemotactic factors.
- Differences in rituximab use between pediatric rheumatologists and nephrologists for the treatment of refractory lupus nephritis and renal flare in childhood-onset SLE.
- Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape.
- Effects of dose and duration of anti-CD154 antibody therapy in preventing renal allograft rejection in a nonhuman primate model.
- Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination.
- Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study.
- Five new epitope-defined monoclonal antibodies reactive with GM2 and human glioma and medulloblastoma cell lines.
- Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia.
- Fluconazole dosing for the prevention or treatment of invasive candidiasis in young infants.
- Genetic control of peripheral leukocyte response to endotoxin in mice.
- Genetic control of the immune response to staphylococcal nuclease. VII. Role of non-H2-linked genes in the control of the anti-nuclease antibody response.
- Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
- Human xenograft-nude mouse model of adoptive immunotherapy with human melanoma-specific cytotoxic T-cells.
- Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence.
- Hyaluronan fragments contribute to the ozone-primed immune response to lipopolysaccharide.
- ICAM-1 (CD54) expression on B lymphocytes is associated with their costimulatory function and can be increased by coactivation with IL-1 and IL-7.
- Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.
- Immunoglobulin prevents complement-mediated hyperacute rejection in swine-to-primate xenotransplantation.
- Individualization of gamma globulin dosage in patients with humoral immunodeficiency.
- Induction of protective CTL responses in newborn mice by a murine retrovirus.
- Infection with Mycobacterium bovis BCG diverts traffic of myelin oligodendroglial glycoprotein autoantigen-specific T cells away from the central nervous system and ameliorates experimental autoimmune encephalomyelitis.
- Influence of HIV-1 infection and cigarette smoking on leukocyte profiles in homosexual men. The Multicenter AIDS Cohort Study.
- Inhibition of in vitro NZB antibody responses by cyclosporine.
- Inhibition of the growth of human melanoma metastases in nude mice by melanoma-specific murine monoclonal antibody.
- Ir genes of different high responder haplotypes for staphylococcal nuclease are not allelic.
- Kinetics of TCR use in response to repeated epitope-specific immunization.
- Ligation of cell surface-associated glucose-regulated protein 78 by receptor-recognized forms of alpha 2-macroglobulin: activation of p21-activated protein kinase-2-dependent signaling in murine peritoneal macrophages.
- Lymphocyte responses to purified ragweed allergens in vitro. I. Proliferative responses in normal, newborn, agammaglobulinemic, and atopic subjects.
- Lymphocyte responses to ragweed antigens from different sources.
- Mapping of a ligand-binding site for the human thromboxane A2 receptor protein.
- Methacholine-induced cutaneous flare response: bivariate analysis of responsiveness and sensitivity.
- Modulation of immunologic responses to HIV-1MN recombinant gp160 vaccine by dose and schedule of administration. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group.
- Modulation of lymphocyte functions by group A streptococcal membrane.
- Neutralizing antibodies to HIV-1 in seronegative volunteers immunized with recombinant gp120 from the MN strain of HIV-1. NIAID AIDS Vaccine Clinical Trials Network.
- Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages.
- Pharmacokinetics of a new 10% intravenous immunoglobulin in patients receiving replacement therapy for primary immunodeficiency.
- Phase 1 clinical trials of the National Institutes of Health Vaccine Research Center HIV/AIDS candidate vaccines.
- Phase 1/2 multiple ascending dose trial of the prostate-specific membrane antigen-targeted antibody drug conjugate MLN2704 in metastatic castration-resistant prostate cancer.
- Phase I/II trial of intermittent subcutaneous IL-2 administration in pediatric patients with moderate immune suppression: results of Pediatric AIDS Clinical Trials Study 402.
- Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1.
- Prolactin can modulate CD4+ T-cell response through receptor-mediated alterations in the expression of T-bet.
- Radiolocalization of human pancreatic tumors in athymic mice by monoclonal antibody DU-PAN 1.
- SMAD4 is required for development of maximal endotoxin tolerance.
- Safety and Immunogenicity of a Single Low Dose or High Dose of Clade 2 Influenza A(H5N1) Inactivated Vaccine in Adults Previously Primed With Clade 1 Influenza A(H5N1) Vaccine.
- Safety and immunogenicity of Env 2-3, a human immunodeficiency virus type 1 candidate vaccine, in combination with a novel adjuvant, MTP-PE/MF59. NIAID AIDS Vaccine Evaluation Group.
- Safety and immunogenicity of an inactivated influenza A/H5N1 vaccine given with or without aluminum hydroxide to healthy adults: results of a phase I-II randomized clinical trial.
- Safety and immunogenicity of one vs. two injections of Oka/Merck varicella vaccine in healthy children.
- Specificity of human bactericidal antibodies against PorA P1.7,16 induced with a hexavalent meningococcal outer membrane vesicle vaccine.
- Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients.
- Studies of high doses of a human immunodeficiency virus type 1 recombinant glycoprotein 160 candidate vaccine in HIV type 1-seronegative humans. The AIDS Vaccine Clinical Trials Network.
- TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity.
- The biological activity of a liposomal complete core lipopolysaccharide vaccine.
- The cytotoxicity and microdosimetry of astatine-211-labeled chimeric monoclonal antibodies in human glioma and melanoma cells in vitro.
- The induction of tolerance and suppression in autoimmune MRL mice using hapten-modified self.
- The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.
- Tumor membrane lymphocyte stimulation assay in patients with renal cell carcinoma.
- Use of a new chemically modified intravenous IgG preparation in severe primary humoral immunodeficiency: clinical efficacy and attempts to individualize dosage.
- Variation in DNA and RNA synthetic responses during activation of lymphocytes from inbred strains of mice.
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Keywords of People
- Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
- Farsiu, Sina, Professor in the Department of Biomedical Engineering, Electrical and Computer Engineering
- Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Immunology