Drug Therapy

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  Subject Areas on Research

  • "Cure" Versus "Clinical Remission": The Impact of a Medication Description on the Willingness of People Living with HIV to Take a Medication. 
  • "If I'm better than average, then I'm ok?": Comparative information influences beliefs about risk and benefits. 
  • "Take your pill": the role and fantasy of pills in modern medicine. 
  • 'Well, It's the Risk of the Unknown… Right?': A Qualitative Study of Perceived Risks and Benefits of HIV Cure Research in the United States. 
  • A new era in pharmacotherapy: the need to understand the principles of therapeutic drug monitoring. 
  • A note on sample size calculation for mean comparisons based on noncentral t-statistics. 
  • Adequacy of antidepressant treatment by psychiatric residents: the antidepressant treatment history form as a possible assessment tool. 
  • Adjustment to college in students with ADHD. 
  • An approach to the assessment of therapeutic drug interactions with fixed combination drug products. 
  • Analysing the relationship between change in a risk factor and risk of disease. 
  • Analysis of primary central nervous system large B-cell lymphoma in the era of high-grade B-cell lymphoma: Detection of two cases with MYC and BCL6 rearrangements in a cohort of 12 cases. 
  • Application of inorganic chemistry for non-cancer therapeutics. 
  • Are chemotherapy patients' HRQoL importance weights consistent with linear scoring rules? A stated-choice approach. 
  • Assessment of advanced gastric cancer management in the United States. 
  • Assessment of bioequivalence using a multiplicative model. 
  • Association of CASP7 polymorphisms and survival of patients with non-small cell lung cancer with platinum-based chemotherapy treatment. 
  • Breast implant-associated anaplastic large-cell lymphoma: long-term follow-up of 60 patients. 
  • Bridging studies in clinical development. 
  • Clinical application of pharmacogenetics: focusing on practical issues. 
  • Collaborative drug therapy management and comprehensive medication management-2015. 
  • Common non-epigenetic drugs as epigenetic modulators. 
  • Congruence of patient- and clinician-reported toxicity in women receiving chemotherapy for early breast cancer. 
  • Cost-effectiveness of treatments for adolescent depression: results from TADS. 
  • Current options for the treatment of neoplastic meningitis. 
  • Cutaneous metastasis of SMARCA4-deficient thoracic sarcoma: A diagnostic dilemma with therapeutic implications. 
  • Dawn of a new era for the American journal of geriatric pharmacotherapy. 
  • Decision support for evidence-based pharmacotherapy detects adherence problems but does not impact medication use. 
  • Development and evaluation of an improved methodology for assessing adherence to evidence-based drug therapy guidelines using claims data. 
  • Development and initial assessment of the medication user self-evaluation (MUSE) tool. 
  • Developmental pharmacogenomics. 
  • Diurnal variations in incidence and outcome of out-of-hospital cardiac arrest including prior comorbidity and pharmacotherapy: a nationwide study in Denmark. 
  • Drug-prescribing in a family medicine residency program with a pharmacotherapeutics curriculum. 
  • Drug-use patterns among black and nonblack community-dwelling elderly. 
  • Economic analysis of targeting chemotherapy using a 21-gene RT-PCR assay in lymph-node-negative, estrogen-receptor-positive, early-stage breast cancer. 
  • Effectiveness of atypical antipsychotics for substance use in schizophrenia patients. 
  • Emerging treatment options for patients with castration-resistant prostate cancer. 
  • Facilitators of adherence to the study pill in the FEM-PrEP clinical trial. 
  • Fine tuning of immunometabolism for the treatment of rheumatic diseases. 
  • Geriatric emergency department guidelines. 
  • Heightened sensitivity to facial expressions of emotion in borderline personality disorder. 
  • Hepatitis C Virus Treatment: Is It Possible To Cure All Hepatitis C Virus Patients? 
  • Identifying risk of readmission in hospitalized elderly adults through inpatient medication exposure. 
  • Impact of Sulfadoxine-Pyrimethamine Resistance on Effectiveness of Intermittent Preventive Therapy for Malaria in Pregnancy at Clearing Infections and Preventing Low Birth Weight. 
  • Impact of comorbid panic and posttraumatic stress disorder on outcomes of collaborative care for late-life depression in primary care. 
  • Impact of inappropriate drug use on health services utilization among representative older community-dwelling residents. 
  • Impact of pediatric exclusivity on drug labeling and demonstrations of efficacy. 
  • Impact of thoracic radiotherapy timing in limited-stage small-cell lung cancer: usefulness of the individual patient data meta-analysis. 
  • Implications of pharmacogenomics for drug development and clinical practice. 
  • Improving the clinical risk score: an analysis of molecular biomarkers in the era of modern chemotherapy for resectable hepatic colorectal cancer metastases. 
  • Inappropriate prescribing for elderly Americans in a large outpatient population. 
  • Incidence and risk factors of significant carotid artery stenosis in asymptomatic survivors of head and neck cancer after radiotherapy. 
  • Initial prognostic factors and lymphoblast-erythrocyte rosette formation in 109 children with acute lymphoblastic leukemia. 
  • Interventions to improve transitional care between nursing homes and hospitals: a systematic review. 
  • Intravitreal Pharmacotherapies for Diabetic Macular Edema: A Report by the American Academy of Ophthalmology. 
  • Intravitreal injection of therapeutic agents. 
  • Is there a role for selective neck dissection after chemoradiation for head and neck cancer? 
  • Late Morbidity and Mortality Among Medulloblastoma Survivors Diagnosed Across Three Decades: A Report From the Childhood Cancer Survivor Study. 
  • Letter by Bourque et al regarding article, "Changing incidence and survival for heart failure in a well-defined older population, 1970-1974 and 1990-1994". 
  • Lopinavir/Ritonavir Monotherapy as Second-line Antiretroviral Treatment in Resource-Limited Settings: Week 104 Analysis of AIDS Clinical Trials Group (ACTG) A5230. 
  • Managing the epileptic patient. 
  • Measuring High-Risk Patients' Preferences for Pharmacogenetic Testing to Reduce Severe Adverse Drug Reaction: A Discrete Choice Experiment. 
  • Mechanisms to provide safe and effective drugs for children. 
  • Medical problems associated with aging. 
  • Medical therapy in the elderly. 
  • Medication discontinuation after curative surgery for sporadic primary hyperparathyroidism. 
  • Medication use in the neonatal intensive care unit. 
  • Mucositis-related morbidity and resource utilization in head and neck cancer patients receiving radiation therapy with or without chemotherapy. 
  • Myelodysplastic syndromes. 
  • National surveillance of herbal dietary supplement exposures: the poison control center experience. 
  • Nosology and measurement in child and adolescent psychiatry. 
  • Nursing home research: the first International Association of Gerontology and Geriatrics (IAGG) research conference. 
  • Objective model using only gender, age and medication list predicts in-hospital morbidity after elective surgery. 
  • Off-target properties of pharmacotherapy and the importance of mechanistic investigations in early clinical phase drug development. 
  • Opportunities for performance improvement in relation to medication administration during pediatric stabilization. 
  • Optimizing operational efficiencies in early phase trials: The Pediatric Trials Network experience. 
  • Overriding psychiatric advance directives: factors associated with psychiatrists' decisions to preempt patients' advance refusal of hospitalization and medication. 
  • PHARMACOLOGICAL ASPECTS OF PARKINSONISM. 
  • Patients' perceptions of the benefits of pharmaceutical care. 
  • Patterns of morphologic alteration in residual rectal carcinoma following preoperative chemoradiation and their association with long-term outcome. 
  • Perioperative management of drug therapy, clinical considerations. 
  • Pharmacoeconomics and the formulary decision-making process. 
  • Pharmacologic approaches to the prevention of type 2 diabetes in high risk pediatric patients. 
  • Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology. 
  • Pharmacotherapy for anxiety disorders in children and adolescents: an evidence-based medicine review. 
  • Pharmacotherapy of postoperative nausea and vomiting. 
  • Physician agreement with pharmacist-suggested drug therapy changes for elderly outpatients. 
  • Physicians' beliefs about faith-based treatments for alcoholism. 
  • Population pharmacokinetic/pharmacodynamic methodology and applications: a bibliography. 
  • Power considerations when a continuous outcome variable is dichotomized. 
  • Practical ethics: establishing a pathway to benefit for complex pharmacogenomic tests. 
  • Primary and Secondary Prevention of Lung Cancer: an International Association for the Study of Lung Cancer workshop. 
  • Psychosocial and biobehavioral factors and their interplay in coronary heart disease. 
  • Quantifying benefit-risk preferences for medical interventions: an overview of a growing empirical literature. 
  • Quantifying nursing workflow in medication administration. 
  • Racial and ethnic disparities in medication use among older adults. 
  • Recruitment of rural and cognitively impaired older adults for dental research. 
  • Relationship between characteristics of medications and drug-induced liver disease phenotype and outcome. 
  • Reliability of a modified medication appropriateness index in ambulatory older persons. 
  • Reliability of drug utilization evaluation as an assessment of medication appropriateness. 
  • Representation of black patients in randomized clinical trials of heart failure with reduced ejection fraction. 
  • Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies. 
  • Self-rated global measure of the frequency, intensity, and burden of side effects. 
  • Sequential development of chronic myelogenous leukemia and primary myelofibrosis in a patient with history of large B-cell lymphoma treated with radiotherapy and chemotherapy: two myeloid neoplasms with distinct genotypic profiles suggestive of biclonality in a single individual. 
  • Sex-related differences in clinical drug response: Implications for women's health 
  • Signet-ring cells in the bone marrow as an indication of cryptic metastasis of breast carcinoma: A case report. 
  • Sleep and psychiatric disorders: future directions. 
  • Spinal cord injury pharmacotherapy: Current research & development and competitive commercial landscape as of 2015. 
  • Statistical methods for bridging studies. 
  • Strategies for treating latent multiple-drug resistant tuberculosis: a decision analysis. 
  • Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. 
  • Talking with patients about dying. 
  • The Dose Response: Perceptions of People Living with HIV in the United States on Alternatives to Oral Daily Antiretroviral Therapy. 
  • The Medication Administration System--Nurses Assessment of Satisfaction (MAS-NAS) scale. 
  • The Texas Medication Algorithm Project antipsychotic algorithm for schizophrenia: 2006 update. 
  • The cost-effectiveness of a clinical pharmacist intervention among elderly outpatients. 
  • The polypill to prevent cardiovascular disease: physicians' perspectives. 
  • The treatment of primary insomnia. 
  • The use of chemotherapy in patients with gliomas: patterns of care in Victoria from 1998-2000. 
  • Therapeutic failure-related hospitalisations in the frail elderly. 
  • Therapeutic potential of β-arrestin- and G protein-biased agonists. 
  • Transient and sustained changes in operational performance, patient evaluation, and medication administration during electronic health record implementation in the emergency department. 
  • Translating genomics into clinical practice: applications in lung cancer. 
  • Treating HCV Infection: It Doesn't Get Much Better Than This. 
  • Treating the health, quality of life, and functional impairments in insomnia. 
  • Trends in human immunodeficiency virus (HIV) counseling, testing, and antiretroviral treatment of HIV-infected women and perinatal transmission in North Carolina. 
  • Trial Characteristics That Affect Parental Consent in Neonatal Drug Trials. 
  • USPHS/IDSA guidelines for the prevention of opportunistic infections in persons infected with human immunodeficiency virus: disease-specific recommendations. USPHS/IDSA Prevention of Opportunistic Infections Working Group. 
  • Using Adherence-Contingent Rebates on Chronic Disease Treatment Costs to Promote Medication Adherence: Results from a Randomized Controlled Trial. 
  • Validation of the Belief Into Action Scale (BIAC) in Portuguese Cancer Patients Receiving Chemotherapy. 
  • Views of older adults on patient participation in medication-related decision making. 
  • Will Precision Medicine Move Us beyond Race? 
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  Keywords of People

  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology