Drug Utilization

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  Subject Areas on Research

  • A Pharmacoepidemiologic Study of the Safety and Effectiveness of Clindamycin in Infants. 
  • A gap analysis approach to assess patient persistence with glaucoma medication. 
  • A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial. 
  • A perilous disconnect: antipsychotic drug use in very young children. 
  • A study of anesthetic drug utilization in different age groups. 
  • A survey of the management of spinal-induced hypotension for scheduled cesarean delivery. 
  • A systematic review of barriers and interventions to improve appropriate use of therapies for sickle cell disease. 
  • Adoption of pharmaceutical innovation and the growth of drug expenditure in Taiwan: is it cost effective? 
  • Adoption of thrombolytic therapy in the management of acute myocardial infarction. 
  • Adverse consequences of neonatal antibiotic exposure. 
  • Agreement and validity of pharmacy data versus self-report for use of osteoporosis medications among chronic glucocorticoid users. 
  • An Analysis of Medicare Reimbursement to Ophthalmologists: Years 2012 to 2013. 
  • An analysis of the Association of Society of Chest Pain Centers Accreditation to American College of Cardiology/American Heart Association non-ST-segment elevation myocardial infarction guideline adherence. 
  • Another excuse bites the dust: low tidal volume ventilation does not increase sedation use. 
  • Antibacterial resistance leadership group: open for business. 
  • Antidepressant medication use in palliative care. 
  • Antidepressant use by race. 
  • Antidepressant use in the elderly: association with demographic characteristics, health-related factors, and health care utilization. 
  • Antihypertensives are administered selectively in emergency department patients with subarachnoid hemorrhage. 
  • Antimicrobial stewardship programs in community hospitals: the evidence base and case studies. 
  • Antimicrobial stewardship programs: how to start and steer a successful program. 
  • Application of new cholesterol guidelines to a population-based sample. 
  • Appropriateness of medication prescribing in ambulatory elderly patients. 
  • Aprotinin use during cardiac surgery: recent alterations and effects on blood product utilization. 
  • Are psychiatrists' characteristics related to how they care for depression in the medically ill? Results from a national case-vignette survey. 
  • Aspirin treatment after myocardial infarction: are health maintenance organization members, women, and the elderly undertreated? 
  • Association between medication possession ratio, virologic failure and drug resistance in HIV-1-infected adults on antiretroviral therapy in Côte d'Ivoire. 
  • Attitudes regarding the use of hematopoietic colony-stimulating factors and maintenance of relative dose intensity among gynecologic oncologists. 
  • Baseline Antihypertensive Drug Count and Patient Response to Hypertension Medication Management. 
  • Benzodiazepine anti-anxiety agents: prevalence and correlates of use in a southern community. 
  • Best Care for Patients Achieved Through Multidisciplinary Stewardship. 
  • Blood cultures and antibiotic use in a neonatal intensive care unit. 
  • Characteristics of treated hypertension in incident hemodialysis and peritoneal dialysis patients. 
  • Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the Cascade Screening for Awareness and Detection-FH Registry. 
  • Combating antimicrobial resistance: policy recommendations to save lives. 
  • Combined use of warfarin and oral P2Y12 inhibitors in patients with atrial fibrillation and acute coronary syndrome. 
  • Comparison of Hydralazine/Nitrate and Angiotensin Receptor Neprilysin Inhibitor Use Among Black Versus Nonblack Americans With Heart Failure and Reduced Ejection Fraction (from CHAMP-HF). 
  • Continuous adductor canal blockade facilitates increased home discharge and decreased opioid consumption after total knee arthroplasty. 
  • Contraindicated medication use in dialysis patients undergoing percutaneous coronary intervention. 
  • Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire. 
  • Current use of beta blockers in patients with reactive airway disease who are hospitalized with acute coronary syndromes. 
  • Decreased use of non-steroidal anti-inflammatory drugs for the treatment of juvenile idiopathic arthritis in the era of modern aggressive treatment. 
  • Denominator Matters in Estimating Antimicrobial Use: A Comparison of Days Present and Patient Days. 
  • Diffusion of technologies for the care of older adults with exudative age-related macular degeneration. 
  • Does anti-malarial drug knowledge predict anti-malarial dispensing practice in drug outlets? A survey of medicine retailers in western Kenya. 
  • Drug therapy team review in a long-term care facility. 
  • Dry eye medication use and expenditures: data from the medical expenditure panel survey 2001 to 2006. 
  • Early treatment for non-ST-segment elevation acute coronary syndrome is associated with appropriate discharge care. 
  • Editorial comment. 
  • Effectiveness of antimicrobial guidelines for community-acquired pneumonia in children. 
  • Establishing an Antimicrobial Stewardship Collaborative Across a Large, Diverse Health Care System. 
  • Factors associated with changes in the use of antiretroviral therapy by a cohort of homosexual men infected with human immunodeficiency virus type 1. 
  • Factors predicting change in prescription and nonprescription drug use in a community-residing black and white elderly population. 
  • Feasibility of Core Antimicrobial Stewardship Interventions in Community Hospitals. 
  • Fibrate use in the United States and Canada. 
  • Fluoroquinolone resistance during 2000-2005: an observational study. 
  • Four States With Robust Prescription Drug Monitoring Programs Reduced Opioid Dosages. 
  • Gender differences in NSAID use among older adults with osteoarthritis. 
  • General practitioners' approach to hypertension in urban Pakistan: disturbing trends in practice. 
  • Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes. 
  • Geographic variations in the use of medical and surgical therapies for benign prostatic hyperplasia. 
  • Get With The Guidelines program participation, process of care, and outcome for Medicare patients hospitalized with heart failure. 
  • Hospital pharmacy decisions, cost containment, and the use of cost-effectiveness analysis. 
  • How direct-to-consumer television advertising for osteoarthritis drugs affects physicians' prescribing behavior. 
  • Impact of FDA Actions, DTCA, and Public Information on the Market for Pain Medication. 
  • Impact of congestive heart failure in patients with non-ST-segment elevation acute coronary syndromes. 
  • Impact of education on cephalosporin prescribing patterns. 
  • Impact of ethnicity and gender differences on angiographic coronary artery disease prevalence and in-hospital mortality in the American College of Cardiology-National Cardiovascular Data Registry. 
  • Improved Quality of Life With Anti-TNF Therapy Compared With Continued Corticosteroid Utilization in Crohn's Disease. 
  • Improving drug prescribing in a primary care practice. 
  • Incidence of statin use in older adults with and without cardiovascular disease and diabetes mellitus, January 2008- March 2018. 
  • Increased number of coagulation products in relationship to red blood cell products transfused improves mortality in trauma patients. 
  • Inpatient Antimicrobial Stewardship in Pediatrics: A Systematic Review. 
  • Inpatient and outpatient patterns of psychotropic drug prescribing by nonpsychiatrist physicians. 
  • Intensity of Lipid Lowering With Statin Therapy in Patients With Cerebrovascular Disease Versus Coronary Artery Disease: Insights from the PALM Registry. 
  • International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. 
  • Is optimal angiotensin-converting enzyme inhibitor dosing neglected in elderly patients with heart failure? 
  • It still hurts! Persistent pain and use of pain medication one year after injury. 
  • Ketorolac is underutilized after ureteral reimplantation despite reduced hospital cost and reduced length of stay. 
  • Knowledge, beliefs, and confidence regarding infections and antimicrobial stewardship: a survey of Veterans Affairs providers who care for older adults. 
  • Lipid management in patients with unstable angina pectoris and non-ST-segment elevation acute myocardial infarction (from CRUSADE). 
  • Long-term analgesic use: sometimes less is not more. 
  • Marked differences in antidepressant use by race in an elderly community sample: 1986-1996. 
  • Medical Therapy for Heart Failure With Reduced Ejection Fraction: The CHAMP-HF Registry. 
  • Medication Discontinuation in the IMPROVE-IT Trial. 
  • Medication Initiation Burden Required to Comply With Heart Failure Guideline Recommendations and Hospital Quality Measures. 
  • Medication Use in the Neonatal Intensive Care Unit and Changes from 2010 to 2018. 
  • Medication oversupply in patients with diabetes. 
  • Medication use and retinal vessel diameters. 
  • Medication use in the neonatal intensive care unit. 
  • Medication use patterns among demented, cognitively impaired and cognitively intact community-dwelling elderly people. 
  • Medicine. Stroke--tPA and the clinic. 
  • Metaanalysis and review of heart failure disease management randomized controlled clinical trials. 
  • Misperceptions about beta-blockers and diuretics: a national survey of primary care physicians. 
  • More educated emergency department patients are less likely to receive opioids for acute pain. 
  • Mycobacteria: treatment approaches and mechanisms of resistance. 
  • National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate. 
  • Neighborhood health center patients who use minor tranquilizers. 
  • New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance. 
  • Nonsteroidal antiinflammatory drug use among patients with GI bleeding. 
  • Off-label applications for SSRIs. 
  • Off-label uses for selective serotonin reuptake inhibitors. 
  • Outpatient prescribing of antiarrhythmic drugs from 1995 to 2000. 
  • PCSK9 Inhibitor Use in the Real World: Data From the National Patient-Centered Research Network. 
  • Patterns of Care for Atrial Fibrillation Before, During, and at Discharge From Hospitalization: From the Get With The Guidelines-Atrial Fibrillation Registry. 
  • Periprocedural outcomes comparing fibroid embolization and focused ultrasound: a randomized controlled trial and comprehensive cohort analysis. 
  • Persistent Opioid Use Among Pediatric Patients After Surgery. 
  • Persistent Opioid Use and High-Risk Prescribing in Body Contouring Patients. 
  • Persistent use of psychotropic drugs in nursing home residents in Norway. 
  • Pharmacologic treatment of posttraumatic stress disorder: a focus on antipsychotic use. 
  • Physician Utilization Patterns for VEGF-Inhibitor Drugs in the 2012 United States Medicare Population: Bevacizumab, Ranibizumab, and Aflibercept. 
  • Physician office visits of adults for anxiety disorders in the United States, 1985-1998. 
  • Point-of-prescription interventions to improve antimicrobial stewardship. 
  • Polypharmacy in patients with advanced cancer and the role of medication discontinuation. 
  • Polypharmacy in pregnant women with major psychiatric illness: a pilot study. 
  • Population-based hepatitis C surveillance and treatment in a national managed care organization. 
  • Postoperative Pain Management in Children of Hispanic Origin: A Descriptive Cohort Study. 
  • Practice Variation in Anticoagulation Prescription and Outcomes After Device-Detected Atrial Fibrillation. 
  • Practitioner acceptance of the dofetilide risk-management program. 
  • Practitioner versus medication-expert opinion on psychiatric pharmacotherapy of mentally retarded patients with mental disorders. 
  • Predicting antipsychotic use in children. 
  • Predictors of antidepressant use among older adults: have they changed over time? 
  • Predictors of delivery of hospital-based heart failure patient education: a report from OPTIMIZE-HF. 
  • Predictors of treatment initiation with tumor necrosis factor-α inhibitors in patients with rheumatoid arthritis. 
  • Prescribing of psychotropics in elderly nursing home patients. 
  • Prevalence and Patterns of Opioid Use Before and After Liver Transplantation. 
  • Prevalence and safety of diazoxide in the neonatal intensive care unit. 
  • Prevalence of depression and its treatment in an elderly population: the Cache County study. 
  • Pro: The Food and Drug Administration Black box warning on droperidol is not justified. 
  • Psychotropic drug prescriptions for nursing home residents. 
  • Psychotropic drugs on general medical and surgical wards of a teaching hospital. 
  • Psychotropic medication use in children with autism in the Kentucky Medicaid population. 
  • Quality of care for atrial fibrillation among patients hospitalized for heart failure. 
  • Racial and ethnic differences in adjuvant hormonal therapy use. 
  • Racial and ethnic disparities in medication use among older adults. 
  • Racial variations in treatment and outcomes of black and white patients with high-risk non-ST-elevation acute coronary syndromes: insights from CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the ACC/AHA Guidelines?). 
  • Rates of glaucoma medication utilization among older adults with suspected glaucoma, 1992 to 2002. 
  • Rates of glaucoma medication utilization among persons with primary open-angle glaucoma, 1992 to 2002. 
  • Rear-view mirror observations on bleeding in acute coronary syndromes. 
  • Reasons for underuse of angiotensin-converting enzyme inhibitors in patients with heart failure and left ventricular dysfunction. 
  • Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative. 
  • Reducing antipsychotic drug prescribing for nursing home patients: a controlled trial of the effect of an educational visit. 
  • Reducing antipsychotic drug use in nursing homes. A controlled trial of provider education. 
  • Reducing long-term diazepam prescribing in office practice. A controlled trial of educational visits. 
  • Reduction in antimicrobial use among medical intensive care unit patients during a cluster randomized crossover trial of palliative care consultation. 
  • Regional Variations in Alirocumab Dosing Patterns in Patients with Heterozygous Familial Hypercholesterolemia During an Open-Label Extension Study. 
  • Regional variation in antenatal corticosteroid use: a network-level quality improvement study. 
  • Results of a Veterans Affairs employee education program on antimicrobial stewardship for older adults. 
  • Retrospective review of amphotericin B use in a tertiary-care medical center. 
  • Rhythm versus rate control in the contemporary management of atrial fibrillation in-hospital. 
  • Risks and benefits of bladder antimuscarinics among elderly residents of Veterans Affairs Community Living Centers. 
  • SUPPORT-AF II: Supporting Use of Anticoagulants Through Provider Profiling of Oral Anticoagulant Therapy for Atrial Fibrillation: A Cluster-Randomized Study of Electronic Profiling and Messaging Combined With Academic Detailing for Providers Making Decisions About Anticoagulation in Patients With Atrial Fibrillation. 
  • Sedation, Analgesia, and Paralysis during Mechanical Ventilation of Premature Infants. 
  • Should we just let the anticoagulation service do it? The conundrum of anticoagulation for atrial fibrillation. 
  • Sildenafil Exposure in the Neonatal Intensive Care Unit. 
  • Statins and age-related macular degeneration: time for a randomized controlled trial? 
  • Successful use of education and cost-based feedback strategies to reduce physician utilization of low-osmolality contrast agents in the cardiac catheterization laboratory. 
  • Temporal Changes in Prescription of Neuropharmacologic Drugs and Utilization of Resources Related to Neurologic Morbidity in Mechanically Ventilated Children With Bronchiolitis. 
  • Temporal Trends in Utilization of Cardiac Therapies and Outcomes for Myocardial Infarction by Degree of Chronic Kidney Disease: A Report From the NCDR Chest Pain-MI Registry. 
  • Temporal trends and predictors in the use of aldosterone antagonists post-acute myocardial infarction. 
  • The James A. Rand Young Investigator's Award: Battling the Opioid Epidemic with Prospective Pain Threshold Measurement. 
  • The application of official policy. Prophylaxis recommendations for patients with mitral valve prolapse. 
  • The association between price, competition, and demand factors on private sector anti-malarial stocking and sales in western Kenya: considerations for the AMFm subsidy. 
  • The association between the supply of select nonpharmacologic providers for pain and use of nonpharmacologic pain management services and initial opioid prescribing patterns for Medicare beneficiaries with persistent musculoskeletal pain. 
  • The atrial FibriLlatiOn real World management registry in the Middle East and Africa: design and rationale. 
  • The effect of Medicaid formularies on the availability of new drugs. 
  • The effects of physician specialty and patient comorbidities on the use and discontinuation of coxibs. 
  • The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries. 
  • The impact of antimicrobial resistance on empiric antibiotic selection and antimicrobial use in clinical practice. 
  • The impact of borderline personality disorder on post-traumatic stress in the community: a study of health status, health utilization, and functioning. 
  • The impact of medication use in a multicomponent intervention: results from the WISEWOMAN program. 
  • The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up. 
  • The safety of warfarin therapy in the nursing home setting. 
  • Total duration instead of in-hospital antibiotic days: reaching beyond the hospital walls. 
  • Trends in age-related macular degeneration management in Singapore. 
  • Trends in the use of evidence-based treatments for coronary artery disease among women and the elderly: findings from the get with the guidelines quality-improvement program. 
  • Under-utilisation of beta-blockers after acute myocardial infarction. Pharmacoeconomic implications. 
  • Understanding the barriers to the dissemination of medical expulsive therapy. 
  • Use of QT Prolonging Medications by Hemodialysis Patients and Individuals Without End-Stage Kidney Disease. 
  • Use of aldosterone antagonists in heart failure. 
  • Use of anticoagulant agents and risk of bleeding among patients admitted with myocardial infarction: a report from the NCDR ACTION Registry--GWTG (National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry--Get With the Guidelines). 
  • Use of antidepressants by nonpsychiatrists in the treatment of medically ill hospitalized depressed elderly patients. 
  • Use of antihypotensive therapies in extremely preterm infants. 
  • Use of antimicrobial drugs in adults before and after removal of a restriction policy. 
  • Use of antithrombotic medications among elderly ischemic stroke patients. 
  • Use of complementary and alternative medicine in men with family history of prostate cancer: a pilot study. 
  • Use of erythropoietin in cancer patients: assessment of oncologists' practice patterns in the United States and other countries. 
  • Use of guideline-recommended therapies for heart failure in the Medicare population. 
  • Use of psychotherapy in a representative adult community sample in São Paulo, Brazil. 
  • Utilization of Standard and Target-Specific Oral Anticoagulants Among Adults in the United Kingdom With Incident Atrial Fibrillation. 
  • Utilization of darbepoetin alfa in relation to cancer patients' hemoglobin levels. 
  • Utilization patterns and characteristics of users of biologic anti-inflammatory agents in a large, US commercially insured population. 
  • Variation in perioperative vasoactive therapy in cardiovascular surgical care: data from the Society of Thoracic Surgeons. 
  • Weekend/holiday versus weekday hospital discharge and guideline adherence (from the American Heart Association's Get with the Guidelines--Coronary Artery Disease database). 
  • Who enrolls in the Medicare Part D prescription drug benefit program? Medication use among patients with heart failure. 
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  Keywords of People

  • Curtis, Lesley H., Professor in Population Health Sciences, Medicine, General Internal Medicine
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology