Duffy Blood-Group System

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  Subject Areas on Research

  • Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program. 
  • Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean. 
  • Erythrocyte blood group antigens: not so simple after all. 
  • Evolution of a malaria resistance gene in wild primates. 
  • Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 
  • Lack of Duffy antigen expression is associated with organ damage in patients with sickle cell disease. 
  • Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum. 
  • The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression. 
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  Keywords of People

  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology