Dyspnea

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  Subject Areas on Research

  • A 27-year-old woman with cough, dyspnea, and wheezing. 
  • A 63-year-old woman with a 2-month history of dyspnea. 
  • A Novel In-hospital Congestion Score to Risk Stratify Patients Admitted for Worsening Heart Failure (from ASCEND-HF). 
  • A caravanning cardiomyopathy. 
  • A change of heart. 
  • A continuous murmur. 
  • A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis. 
  • A review of dyspnea in acute heart failure syndromes. 
  • A review of quality of care evaluation for the palliation of dyspnea. 
  • ACR Appropriateness Criteria® Dyspnea-Suspected Cardiac Origin (Ischemia Already Excluded): 2021 Update. 
  • ACR Appropriateness Criteria® Dyspnea-Suspected Cardiac Origin. 
  • Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) Trial. 
  • Acute decompensated heart failure: update on new and emerging evidence and directions for future research. 
  • Adverse reaction characterized by chest pain, shortness of breath, and syncope associated with verteporfin (visudyne). 
  • Alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy. A multicenter North American registry. 
  • An unexpected echocardiographic image in a patient with dyspnea. 
  • An unusual cause of dyspnoea in a young man. 
  • Angiographic evaluation of chronic pulmonary embolism. 
  • Aortocaval fistula complicating abdominal aortic aneurysm: case report and literature review. 
  • Arrival by ambulance in acute heart failure: insights into the mode of presentation from Acute Studies of Nesiritide in Decompensated Heart Failure (ASCEND-HF). 
  • Assessing exertional dyspnea in patients with idiopathic pulmonary fibrosis. 
  • Assessment of dyspnea in acute decompensated heart failure: insights from ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure) on the contributions of peak expiratory flow. 
  • Assessment of the psychometric properties of an English version of the cancer dyspnea scale in people with advanced lung cancer. 
  • B-type natriuretic peptide - a biomarker for all seasons? 
  • Beneficial effects of albuterol therapy driven by heliox versus by oxygen in severe asthma exacerbation. 
  • Bilateral nodular pulmonary infiltrates in an immunocompromised host. 
  • Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From the ASCEND-HF Trial. 
  • Brief report: idiopathic diffuse hyperplasia of pulmonary neuroendocrine cells and airways disease. 
  • Bronchial provocation tests before and after cessation of smoking. 
  • Building the palliative care evidence base: Lessons from a randomized controlled trial of oxygen vs room air for refractory dyspnea. 
  • Byssinosis and chronic bronchitis among cotton textile workers. 
  • CT metrics of airway disease and emphysema in severe COPD. 
  • Cardiac angiosarcoma presenting as progressive dyspnea on exertion. 
  • Cases from the Osler Medical Service at Johns Hopkins University. 
  • Cases from the Osler Medical Service at Johns Hopkins University. Diffuse colonic angiodysplasia with chronic iron deficiency anemia. 
  • Changes in Dyspnea Status During Hospitalization and Postdischarge Health-Related Quality of Life in Patients Hospitalized for Heart Failure: Findings From the EVEREST Trial. 
  • Characteristics of lung cancer in elderly patients. 
  • Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes. 
  • Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes. 
  • Clinical Decision Support for Symptom Management in Lung Cancer Patients: A Group RCT. 
  • Clinical and radiographic predictors of successful therapeutic bronchoscopy for the relief of malignant central airway obstruction. 
  • Clinical problem-solving. A hole in the argument. 
  • Clinical problem-solving. A key miscommunication--an 81-year-old woman presented to the emergency department with increasing abdominal distention, nausea, and vomiting. 
  • Clinical problem-solving. Needle in a haystack. 
  • Clinical problem-solving. Undercover and overlooked. 
  • Cold Water, Hard Swim, Shortness of Breath: How to Assess? 
  • Comparison of Dyspnea Measurement Instruments in Acute Heart Failure: The DYSPNEA-AHF Pilot Study. 
  • Coronary arteriovenous fistulae: the complexity of coronary artery-to-coronary sinus connections. 
  • Correlation between peak expiratory flow rate and NT-proBNP in patients with acute heart failure. An analysis from ASCEND-HF trial. 
  • Critical arrhythmia associated with pulmonary artery catheterization in a parturient with severe pulmonary hypertension. 
  • Decongestion in acute heart failure. 
  • Delayed postmyectomy ventricular septal defect. 
  • Diagnosis of pheochromocytoma on physical examination. 
  • Differences between patients with cardiovascular disease and cancer referred for palliative care. 
  • Diffusing Capacity of the Lungs for Carbon Monoxide Test. 
  • Discordances between predicted and actual risk in obese patients with suspected cardiac ischaemia. 
  • Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure. 
  • Distant wheezes. 
  • Diuretic response in acute heart failure: clinical characteristics and prognostic significance. 
  • Diuretic strategies in patients with acute decompensated heart failure. 
  • Does This Child Have Pneumonia?: The Rational Clinical Examination Systematic Review. 
  • Does this patient have pulmonary embolism? 
  • Dyspnea and Pulmonary Hypertension with Diffuse Centrilobular Nodules. 
  • Dyspnea and hypoxia in a 64-year-old male traveler. 
  • Dyspnea and pain frequently co-occur among Medicare managed care recipients. 
  • Dyspnea in Community-Dwelling Older Persons: A Multifactorial Geriatric Health Condition. 
  • Dyspnea review for the palliative care professional: assessment, burdens, and etiologies. 
  • Dyspnea review for the palliative care professional: treatment goals and therapeutic options. 
  • Dyspnoea and worsening heart failure in patients with acute heart failure: results from the Pre-RELAX-AHF study. 
  • Dyspnoea in patients with acute heart failure: an analysis of its clinical course, determinants, and relationship to 60-day outcomes in the PROTECT pilot study. 
  • Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study. 
  • Effect of a Triage-Based Screening Protocol on Diagnosis and Treatment of Acute Coronary Syndrome in a Tanzanian Emergency Department: A Prospective Pre-Post Study. 
  • Effect of nesiritide in patients with acute decompensated heart failure. 
  • Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: a double-blind, randomised controlled trial. 
  • Effects of serelaxin in subgroups of patients with acute heart failure: results from RELAX-AHF. 
  • Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials. 
  • Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure. 
  • Efficacy and safety of sustained-release propafenone (propafenone SR) for patients with atrial fibrillation. 
  • Endotracheal flumazenil: a new route of administration for benzodiazepine antagonism. 
  • Evaluating treatment efficacy by multiple end points in phase II acute heart failure clinical trials: analyzing data using a global method. 
  • Evaluation of Novel Metrics of Symptom Relief in Acute Heart Failure: The Worst Symptom Score. 
  • Evaluation of a provocative dyspnea severity score in acute heart failure. 
  • Exertional dyspnea in heart failure: a symptom unrelated to pulmonary function at rest or during exercise. Duke University Clinical Cardiology Studies (DUCCS) Exercise Group. 
  • Hemodynamic findings in severe tricuspid regurgitation. 
  • History of Atrial Fibrillation and Trajectory of Decongestion in Acute Heart Failure. 
  • How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. Results from the Breathing Not Properly Multinational Study. 
  • Hydroxychloroquine: a treatable cause of cardiomyopathy. 
  • Immunofibrotic drivers of impaired lung function in postacute sequelae of SARS-CoV-2 infection. 
  • Implementation and Effectiveness of a Veterans Affairs-Based Comprehensive Lung Cancer Survivorship Program. 
  • Importance of echocardiography in patients with severe nonischemic heart failure: the second Prospective Randomized Amlodipine Survival Evaluation (PRAISE-2) echocardiographic study. 
  • Improving the management of dyspnea in the community using rapid learning approaches. 
  • Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study. 
  • Incidental Squamous Cell Carcinoma In Situ in a Large Pharyngoesophageal (Zenker's) Diverticulum. 
  • Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure). 
  • Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial. 
  • Isolated partial anomalous pulmonary venous return with intact atrial septum: a rare but treatable cause of pulmonary hypertension in adults. 
  • Lung volume reduction surgery for the management of refractory dyspnea in chronic obstructive pulmonary disease. 
  • Management of dyspnea in patients with chronic obstructive pulmonary disease. 
  • Management of dyspnea within a rapid learning healthcare model. 
  • Management of terminal cancer in elderly patients. 
  • Markers of decongestion, dyspnea relief, and clinical outcomes among patients hospitalized with acute heart failure. 
  • Morbidity and mortality after pancreaticoduodenectomy in patients with borderline resectable type C clinical classification. 
  • National Academy of Clinical Biochemistry Laboratory Medicine practice guidelines: Clinical utilization of cardiac biomarker testing in heart failure. 
  • Natriuretic peptides in the diagnosis and management of heart failure. 
  • Nesiritide in acute decompensated heart failure. 
  • Nesiritide in patients hospitalized for acute heart failure: does timing matter? Implication for future acute heart failure trials. 
  • Optimal management of malignant pleural effusions (results of CALGB 30102). 
  • Outcomes after esophagectomy: a ten-year prospective cohort. 
  • Oxygen for relief of dyspnea: what is the evidence? 
  • Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: a systematic review and meta-analysis. 
  • Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis. 
  • Ozone-induced respiratory symptoms: exposure-response models and association with lung function. 
  • Palliative management of refractory dyspnea in COPD. 
  • Patterns of Emergency Care for Possible Acute Coronary Syndrome Among Patients with Chest Pain or Shortness of Breath at a Tanzanian Referral Hospital. 
  • Peripartum cardiomyopathy presenting as an acute myocardial infarction. 
  • Personal Growth and Associated Factors Among Patients with Chronic Obstructive Pulmonary Disease in China: A Cross-Sectional Study. 
  • Phenotype of Spirometric Impairment in an Aging Population. 
  • Platypnea-Orthodeoxia Syndrome: To Shunt or Not to Shunt, That is the Question. 
  • Platypnea-orthodeoxia and progressive autonomic failure. 
  • Positional dyspnea and tracheal compression as indications for goiter resection. 
  • Practical Dyspnea Assessment: Relationship Between the 0-10 Numerical Rating Scale and the Four-Level Categorical Verbal Descriptor Scale of Dyspnea Intensity. 
  • Predictors of early dyspnoea relief in acute heart failure and the association with 30-day outcomes: findings from ASCEND-HF. 
  • Preprocessing cotton to prevent byssinosis. 
  • Presenting Symptoms in Patients Undergoing Coronary Artery Disease Evaluation: Association With Noninvasive Test Results and Clinical Outcomes in the PROMISE Trial. 
  • Prognostic Value of Coronary Artery Calcium in the PROMISE Study (Prospective Multicenter Imaging Study for Evaluation of Chest Pain). 
  • Prognostic validation of the body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index in inoperable non-small-cell lung cancer. 
  • Psycho-emotional manifestations of valvular heart diseases: prospective assessment in mitral regurgitation. 
  • Ranolazine for Treatment of Angina or Dyspnea in Hypertrophic Cardiomyopathy Patients (RHYME). 
  • Ranolazine-related dyspnea on exertion. 
  • Rationale and Design of the ATHENA-HF Trial: Aldosterone Targeted Neurohormonal Combined With Natriuresis Therapy in Heart Failure. 
  • Rationale and design of the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure Trial (ASCEND-HF). 
  • Recommended patient-reported core set of symptoms to measure in adult cancer treatment trials. 
  • Relation of dyspnea severity on admission for acute heart failure with outcomes and costs. 
  • Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease. 
  • Relief and Recurrence of Congestion During and After Hospitalization for Acute Heart Failure: Insights From Diuretic Optimization Strategy Evaluation in Acute Decompensated Heart Failure (DOSE-AHF) and Cardiorenal Rescue Study in Acute Decompensated Heart Failure (CARESS-HF). 
  • Risk factors and mortality in invasive Rasamsonia spp. infection: Analysis of cases in the FungiScope® registry and from the literature. 
  • Screening for panic-related anxiety in emergency department patients with cardiopulmonary complaints: A comparison of two self-report instruments. 
  • Secundum atrial septal defect. 
  • Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial. 
  • Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial. 
  • Sex differences in early dyspnea relief between men and women hospitalized for acute heart failure: insights from the RELAX-AHF study. 
  • Sexual concerns in lung cancer patients: an examination of predictors and moderating effects of age and gender. 
  • Shared genomic architecture between COVID-19 severity and numerous clinical and physiologic parameters revealed by LD score regression analysis. 
  • Short-term effects of formaldehyde on peak expiratory flow and irritant symptoms. 
  • Shortness of breath and edema after heart surgery. 
  • Shortness of breath as a predictor of depressive symptoms in a community sample of older adults. 
  • Sometimes it is Not as Simple as Sepsis: An Unusual Cause of Coagulopathy. 
  • Symptom Burden and Performance Status among Community-Dwelling Patients with Serious Illness. 
  • Symptom Burden of Chronic Lung Disease Compared with Lung Cancer at Time of Referral for Palliative Care Consultation. 
  • Symptomatic oxygen for non-hypoxaemic chronic obstructive pulmonary disease. 
  • The Burden of Congestion in Patients Hospitalized With Acute Decompensated Heart Failure. 
  • The PROTECT pilot study: a randomized, placebo-controlled, dose-finding study of the adenosine A1 receptor antagonist rolofylline in patients with acute heart failure and renal impairment. 
  • The Prospective Evaluation of the Net Effect of Red Blood Cell Transfusions in Routine Provision of Palliative Care. 
  • The Rational Clinical Examination. Does this patient have abnormal central venous pressure? 
  • The UCSD shortness of breath questionnaire has longitudinal construct validity in idiopathic pulmonary fibrosis. 
  • The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries. 
  • The impact of induction chemotherapy and the associated tumor response on subsequent radiation-related changes in lung function and tumor response. 
  • The worst symptom as defined by patients during heart failure hospitalization: implications for response to therapy. 
  • Therapeutic bronchoscopy for malignant central airway obstruction: success rates and impact on dyspnea and quality of life. 
  • Ticagrelor versus clopidogrel in patients with acute coronary syndromes. 
  • Titrating Oxygen Requirements During Exercise: Evaluation of a Standardized Single Walk Test Protocol. 
  • Unexplained Dyspnea on Exertion: The Difference the Right Test Can Make. 
  • Video-assisted wedge resection and local radiotherapy for peripheral lung cancer in high-risk patients: the Cancer and Leukemia Group B (CALGB) 9335, a phase II, multi-institutional cooperative group study. 
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  Keywords of People

  • Abbruzzese, James, D. C. I. Distinguished Professor of Medical Oncology, Medicine, Medical Oncology
  • ElMallah, Mai, Associate Professor of Pediatrics, Cell Biology
  • LeBlanc, Thomas William, Associate Professor of Medicine, Duke Cancer Institute
  • Mentz, Robert John, Associate Professor of Medicine, Medicine, Cardiology
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology