Elasticity

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  Subject Areas on Research

  • 'Seeing' Strain in Soft Materials. 
  • A Biomechanical Evaluation of Auricular Cartilage Autografts in Orbital Floor Defect Repair. 
  • A finite element model of remote palpation of breast lesions using radiation force: factors affecting tissue displacement. 
  • A finite-element method model of soft tissue response to impulsive acoustic radiation force. 
  • A novel interpolation strategy for estimating subsample speckle motion. 
  • A novel micropipet method for measuring the bending modulus of vesicle membranes. 
  • A piece-wise non-linear elastic stress expression of human and pig coronary arteries tested in vitro. 
  • A thin-layer model for viscoelastic, stress-relaxation testing of cells using atomic force microscopy: do cell properties reflect metastatic potential? 
  • Accounting for the Spatial Observation Window in the 2-D Fourier Transform Analysis of Shear Wave Attenuation. 
  • Acoustic radiation force impulse imaging of the mechanical properties of arteries: in vivo and ex vivo results. 
  • Active cellular materials. 
  • Age-related changes in cardiac structure and function in Fischer 344 x Brown Norway hybrid rats. 
  • Aging of the skin: implications for cutaneous surgery. 
  • Alterations in the Young's modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage. 
  • Altered trabecular bone structure and delayed cartilage degeneration in the knees of collagen VI null mice. 
  • Alveolar septal structure in different species. 
  • American Gastroenterological Association Institute Technical Review on the Role of Elastography in Chronic Liver Diseases. 
  • An analytic, Fourier domain description of shear wave propagation in a viscoelastic medium using asymmetric Gaussian sources. 
  • An in vitro assessment of acoustic radiation force impulse imaging for visualizing cardiac radiofrequency ablation lesions. 
  • Analysis of ankle deflection during a forward fall in snowboarding. 
  • Analysis of contrast in images generated with transient acoustic radiation force. 
  • Anomalous bending effect in photonic crystal fibers. 
  • Aortic distensibility and retinal arteriolar narrowing: the multi-ethnic study of atherosclerosis. 
  • Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation. 
  • Arterial stiffness and cardiovascular events: the Framingham Heart Study. 
  • Association Between Long-Term Blood Pressure Variability and 10-Year Progression in Arterial Stiffness: The Multiethnic Study of Atherosclerosis. 
  • Associations of aortic distensibility and arterial elasticity with long-term visit-to-visit blood pressure variability: the Multi-Ethnic Study of Atherosclerosis (MESA). 
  • Atomic force and total internal reflection fluorescence microscopy for the study of force transmission in endothelial cells. 
  • Bacteriophage capsids: tough nanoshells with complex elastic properties. 
  • Bending stiffness and pull-out strength of tapered, variable pitch screws, and 6.5-mm cancellous screws in acute Jones fractures. 
  • Bilayers as protein solvents: role of bilayer structure and elastic properties. 
  • Biomechanical analysis of silicon microelectrode-induced strain in the brain. 
  • Biomechanical characteristics of human ankle ligaments. 
  • Biomechanics and pathophysiology of overuse tendon injuries: ideas on insertional tendinopathy. 
  • Biophysical properties of the zona pellucida measured by capillary suction: is zona hardening a mechanical phenomenon? 
  • Can Dissipative Properties of Single Molecules Be Extracted from a Force Spectroscopy Experiment? 
  • Cartilage mechanics in the guinea pig model of osteoarthritis studied with an osmotic loading method. 
  • Cell mechanics: dissecting the physical responses of cells to force. 
  • Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM. 
  • Characterization of Viscoelastic Materials Using Group Shear Wave Speeds. 
  • Characterization of perfused and sectioned liver tissue in a full indentation cycle using a visco-hyperelastic model. 
  • Characterization of the passive responses of live skeletal muscle using the quasi-linear theory of viscoelasticity. 
  • Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds. 
  • Circumferential tensile stiffness of glaucomatous trabecular meshwork. 
  • Co-assembling peptides as defined matrices for endothelial cells. 
  • Comment on "On Dowell's simplification for acoustic cavity-structure interaction and consistent alternatives" [J. Acoust. Soc. Am. 127, 22-32 (2010)]. 
  • Comparison of Corneal Biomechanical Properties between Indian and Chinese Adults. 
  • Comparison of corneal biomechanical properties between healthy blacks and whites using the Ocular Response Analyzer. 
  • Conformation and elasticity of the isolated red blood cell membrane skeleton. 
  • Corneal Biomechanics and Visual Field Progression in Eyes with Seemingly Well-Controlled Intraocular Pressure. 
  • Corneal Hysteresis and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma. 
  • Correspondence of low mean shear and high harmonic content in the porcine iliac arteries. 
  • Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern. 
  • Cyclic loading alters biomechanical properties and secretion of PGE2 and NO from tendon explants. 
  • Cytotoxicity and thermomechanical behavior of biomedical shape-memory polymer networks post-sterilization. 
  • Deformation and collapse of microtubules on the nanometer scale. 
  • Derivation and analysis of viscoelastic properties in human liver: impact of frequency on fibrosis and steatosis staging. 
  • Detecting solvent-driven transitions of poly(A) to double-stranded conformations by atomic force microscopy. 
  • Determination of optimal graft lengths for posterior cruciate ligament reconstruction--a theoretical analysis. 
  • Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration. 
  • Development and characterization of a vitreous mimicking material for radiation force imaging. 
  • Development of a YIGSR-peptide-modified polyurethaneurea to enhance endothelialization. 
  • Diastolic anisotropic properties of the left ventricle in the conscious dog. 
  • Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow. 
  • Directed intermixing in multicomponent self-assembling biomaterials. 
  • Disparity mapping applied to sonography of the breast: technical note. 
  • Dorsal root ganglia neurite extension is inhibited by mechanical and chondroitin sulfate-rich interfaces. 
  • Drained secant modulus for human and porcine peripapillary sclera using unconfined compression testing. 
  • Dynamic infrared linear dichroism study of the temperature-dependent, viscoelastic behavior of a poly(ester urethane). 
  • Dynamic mechanical response of elastic spherical inclusions to impulsive acoustic radiation force excitation. 
  • Dynamics and elasticity of the fibronectin matrix in living cell culture visualized by fibronectin-green fluorescent protein. 
  • Dynamics of neutrophil membrane compliance and microstructure probed with a micropipet-based piconewton force transducer. 
  • Effect of chain length and unsaturation on elasticity of lipid bilayers. 
  • Effect of uniaxial, cyclic stretch on the morphology of monocytes/macrophages in culture. 
  • Effectiveness of intermittent pulsatile elastic stockings for the prevention of calf and thigh vein thrombosis in patients undergoing elective knee surgery. 
  • Elastic deformation and failure of lipid bilayer membranes containing cholesterol. 
  • Elastic energy storage in the mantis shrimp's fast predatory strike. 
  • Elastic hydrogel as a sensor for detection of mechanical stress generated by single cells grown in three-dimensional environment. 
  • Elastic image mapping for 4-D dose estimation in thoracic radiotherapy. 
  • Elastic properties of normal and hypertrophied cardiac muscle. 
  • Elastic properties of single amylose chains in water: a quantum mechanical and AFM study. 
  • Elastic response, buckling, and instability of microtubules under radial indentation. 
  • Elasticity, strength, and water permeability of bilayers that contain raft microdomain-forming lipids. 
  • Electro-mechanical permeabilization of lipid vesicles. Role of membrane tension and compressibility. 
  • Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy. 
  • Endothelialization of microporous YIGSR/PEG-modified polyurethaneurea. 
  • Epidural anesthesia and acutely increased intracranial pressure. Lumbar epidural space hydrodynamics in a porcine model. 
  • Estimates of echo correlation and measurement bias in acoustic radiation force impulse imaging. 
  • Evaluation of biaxial mechanical properties of soft tubes and arteries using sonometry. 
  • Evaluation of the influence of corneal biomechanical properties on intraocular pressure measurements using the ocular response analyzer. 
  • Evidence for the role of cell stiffness in modulation of volume-regulated anion channels. 
  • Evidence of biomechanical and collagen heterogeneity in uterine fibroids. 
  • Evolution of load transfer between hydroxyapatite and collagen during creep deformation of bone. 
  • Experimentally validated multiphysics computational model of focusing and shock wave formation in an electromagnetic lithotripter. 
  • Failure of viral shells. 
  • Fingerprinting polysaccharides with single-molecule atomic force microscopy. 
  • Finite element modeling of impulsive excitation and shear wave propagation in an incompressible, transversely isotropic medium. 
  • Flexible histone tails in a new mesoscopic oligonucleosome model. 
  • Fluctuation-dissipation theorem in an aging colloidal glass. 
  • Force measurements of the alpha5beta1 integrin-fibronectin interaction. 
  • Fragility and mechanosensing in a thermalized cytoskeleton model with forced protein unfolding. 
  • Frictional contact mechanics methods for soft materials: application to tracking breast cancers. 
  • From bouncy legs to poisoned arrows: elastic movements in invertebrates. 
  • Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aorta. 
  • Heparin neutralization by recombinant platelet factor 4 and protamine. 
  • High-frequency stress relaxation in semiflexible polymer solutions and networks. 
  • High-resolution microrheology in the pericellular matrix of prostate cancer cells. 
  • Hydration and conformational mechanics of single, end-tethered elastin-like polypeptides. 
  • Identification of material properties of orthotropic elastic cylinders immersed in fluid using vibroacoustic techniques. 
  • Immunofluorescence-guided atomic force microscopy to measure the micromechanical properties of the pericellular matrix of porcine articular cartilage. 
  • Importance of nonlinear and multivariable flexibility coefficients in the prediction of human cervical spine motion. 
  • In situ friction measurement on murine cartilage by atomic force microscopy. 
  • In vitro monitoring of the dynamic elasticity changes during radiofrequency ablation with acoustic radiation force impulse imaging. 
  • In vivo quantification of liver stiffness in a rat model of hepatic fibrosis with acoustic radiation force. 
  • Increasing the maximum achievable strain of a covalent polymer gel through the addition of mechanically invisible cross-links. 
  • Inertial properties and loading rates affect buckling modes and injury mechanisms in the cervical spine. 
  • Injectable tissue integrating networks from recombinant polypeptides with tunable order. 
  • Interaction between shock wave and single inertial bubbles near an elastic boundary 
  • Is early age-related macular degeneration related to carotid artery stiffness? The Atherosclerosis Risk in Communities Study. 
  • Jumping to rafts: gatekeeper role of bilayer elasticity. 
  • Large deformation finite element analysis of micropipette aspiration to determine the mechanical properties of the chondrocyte. 
  • Leukocyte rolling on P-selectin: a three-dimensional numerical study of the effect of cytoplasmic viscosity. 
  • Leveraging single protein polymers to measure flexural rigidity. 
  • Log-rolling micelles in sheared amphiphilic thin films. 
  • Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4. 
  • Mapping the structural properties of the lumbosacral vertebral endplates. 
  • Measurement of biaxial mechanical properties of soft tubes and arteries using piezoelectric elements and sonometry. 
  • Mechanical Properties of a Drosophila Larval Chordotonal Organ. 
  • Mechanical anisotropy of ankyrin repeats. 
  • Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering. 
  • Mechanical energy and effective foot mass during impact loading of walking and running. 
  • Mechanics of electrocompression of lipid bilayer membranes. 
  • Metabolic requirements of contractile force generation in platelet rich plasma - a rheological study. 
  • Microrheology probes length scale dependent rheology. 
  • Microrheology, stress fluctuations, and active behavior of living cells. 
  • Modulating the mechanical properties of self-assembled peptide hydrogels via native chemical ligation. 
  • Multicenter Evaluation of the Quantra QPlus System in Adult Patients Undergoing Major Surgical Procedures. 
  • Multicomponent patterning of indium tin oxide. 
  • Multilevel analysis of elastic morphology: The mantis shrimp's spring. 
  • Myocardial relaxation and passive diastolic properties in man. 
  • Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength. 
  • Nanomechanical fingerprints of UV damage to DNA. 
  • Nanoscale structures and mechanics of barnacle cement. 
  • Nanospring behaviour of ankyrin repeats. 
  • No association of 9p21 with arterial elasticity and retinal microvascular findings. 
  • Non-linear viscoelastic properties of cervical mucus. 
  • Nonequilibrium dynamics of probe filaments in actin-myosin networks. 
  • Nonequilibrium mechanics of active cytoskeletal networks. 
  • Noninvasive assessment of wall-shear rate and vascular elasticity using combined ARFI/SWEI/spectral Doppler imaging system. 
  • Nonlinear dependence of hydraulic conductivity on tissue deformation during intratumoral infusion. 
  • Normal aging alters in vivo passive biomechanical response of the rat gastrocnemius-Achilles muscle-tendon unit. 
  • Observations of tissue response to acoustic radiation force: opportunities for imaging. 
  • On mechanisms of improved ejection fraction by early reperfusion in acute myocardial infarction: myocardial salvage or infarct stiffening? 
  • On the feasibility of remote palpation using acoustic radiation force. 
  • On the thermal effects associated with radiation force imaging of soft tissue. 
  • Optical tracking of acoustic radiation force impulse-induced dynamics in a tissue-mimicking phantom. 
  • Orientation of elastic fibers in the human cervix. 
  • Origin of overstretching transitions in single-stranded nucleic acids. 
  • Osmotic loading to determine the intrinsic material properties of guinea pig knee cartilage. 
  • Overexpression of lysyl oxidase to increase matrix crosslinking and improve tissue strength in dermal wound healing. 
  • Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients. 
  • PEGDA hydrogels with patterned elasticity: Novel tools for the study of cell response to substrate rigidity. 
  • Packing and viscoelasticity of polyunsaturated omega-3 and omega-6 lipid bilayers as seen by (2)H NMR and X-ray diffraction. 
  • Plastic deformation in pediatric fractures: mechanism and treatment. 
  • Polysaccharide elasticity governed by chair-boat transitions of the glucopyranose ring. 
  • Porcine carotid arterial material property alterations with induced atheroma: an in vivo study. 
  • Preoperative assessment of left ventricular function in patients selected for direct myocardial revascularization. 
  • Probing the Link among Genomic Cargo, Contact Mechanics, and Nanoindentation in Recombinant Adeno-Associated Virus 2. 
  • Probing the folded state of fibronectin type III domains in stretched fibrils by measuring buried cysteine accessibility. 
  • Pseudoelastic intramedullary nailing for tibio-talo-calcaneal arthrodesis. 
  • Pulling geometry-induced errors in single molecule force spectroscopy measurements. 
  • Pullout strength of suture anchors: effect of mechanical properties of trabecular bone. 
  • Pulmonary vascular impedance analysis of adaptation to chronically elevated blood flow in the awake dog. 
  • Quantifying cellular traction forces in three dimensions. 
  • Quantifying hepatic shear modulus in vivo using acoustic radiation force. 
  • Quantifying skeletal muscle properties in cadaveric test specimens: effects of mechanical loading, postmortem time, and freezer storage. 
  • Quantitation of vascular outflow by measurement of impedance. 
  • Quantitative assessment of cervical softening during pregnancy in the Rhesus macaque with shear wave elasticity imaging. 
  • Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication. 
  • Rapid flow of passive neutrophils into a 4 microns pipet and measurement of cytoplasmic viscosity. 
  • Recurrent abdominal laxity following interpositional human acellular dermal matrix. 
  • Regional material property alterations in porcine femoral arteries with atheroma development. 
  • Relationship between carotid artery stiffness and retinal arteriolar narrowing in healthy middle-aged persons. 
  • Reverse engineering of the giant muscle protein titin. 
  • Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin. 
  • Rheological properties of living cytoplasm: a preliminary investigation of squid axoplasm (Loligo pealei). 
  • Rheological properties of living cytoplasm: endoplasm of Physarum plasmodium. 
  • Role of corneal elasticity in damping of intraocular pressure. 
  • Role of pericellular matrix in development of a mechanically functional neocartilage. 
  • Role of the membrane cortex in neutrophil deformation in small pipets. 
  • Round versus flat: bone cell morphology, elasticity, and mechanosensing. 
  • Shear Modulus Measurement by Quantitative Phase Imaging and Correlation with Atomic Force Microscopy. 
  • Shear-wave generation using acoustic radiation force: in vivo and ex vivo results. 
  • Simulating force-induced conformational transitions in polysaccharides with the SMD replica exchange method. 
  • Simultaneous identification of elastic properties, thickness, and diameter of arteries excited with ultrasound radiation force. 
  • Spatial mapping of the biomechanical properties of the pericellular matrix of articular cartilage measured in situ via atomic force microscopy. 
  • Spectral domain phase microscopy for local measurements of cytoskeletal rheology in single cells. 
  • Stiffness of simulated radial neck fractures fixed with 4 different devices. 
  • Stochastic hyperelastic constitutive laws and identification procedure for soft biological tissues with intrinsic variability. 
  • Stretch-induced nitric oxide modulates mechanical properties of skeletal muscle cells. 
  • Stretching fibronectin. 
  • Stretching single protein molecules: titin is a weird spring. 
  • Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins. 
  • Structural and mechanical study of a self-assembling protein nanotube. 
  • Structure and mechanical properties of giant lipid (DMPC) vesicle bilayers from 20 degrees C below to 10 degrees C above the liquid crystal-crystalline phase transition at 24 degrees C. 
  • Structure and thermomechanical behavior of NiTiPt shape memory alloy wires. 
  • Swimming of spermatozoa in a linear viscoelastic fluid. 
  • Tau protein binding forms a 1 nm thick layer along protofilaments without affecting the radial elasticity of microtubules. 
  • Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling. 
  • The 2004 Biophysical Society-Avanti Award in Lipids address: roles of bilayer structure and elastic properties in peptide localization in membranes. 
  • The Relationship Between Asymmetries of Corneal Properties and Rates of Visual Field Progression in Glaucoma Patients. 
  • The effect of aging on low-fat, reduced-fat, and full-fat Cheddar cheese texture. 
  • The effect of length on the structural properties of an Achilles tendon graft as used in posterior cruciate ligament reconstruction. 
  • The effects of bone density and disc degeneration on the structural property distributions in the lower lumbar vertebral endplates. 
  • The effects of pressure-induced right ventricular hypertrophy on left ventricular diastolic properties and dynamic geometry in the conscious dog. 
  • The force-driven conformations of heparin studied with single molecule force microscopy. 
  • The impact of hepatic pressurization on liver shear wave speed estimates in constrained versus unconstrained conditions. 
  • The impact of physiological motion on tissue tracking during radiation force imaging. 
  • The influence of patient age and bone mineral density on osteotomy fixation stability after hallux valgus surgery: A biomechanical study. 
  • The influence of strain rate on the passive and stimulated engineering stress--large strain behavior of the rabbit tibialis anterior muscle. 
  • The measurement of the variation in the surface strains of Achilles tendon grafts using imaging techniques. 
  • The mechanical properties of early Drosophila embryos measured by high-speed video microrheology. 
  • The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model. 
  • The molecular elasticity of the extracellular matrix protein tenascin. 
  • The motion of a single molecule, the lambda-receptor, in the bacterial outer membrane. 
  • The prediction of stress-relaxation of ligaments and tendons using the quasi-linear viscoelastic model. 
  • The role of F-actin and myosin in epithelial cell rheology. 
  • The viscoelastic responses of the human cervical spine in torsion: experimental limitations of quasi-linear theory, and a method for reducing these effects. 
  • Thermomechanics of the shape memory effect in polymers for biomedical applications. 
  • Time-dependent recovery of passive neutrophils after large deformation. 
  • Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. 
  • Titanium with aligned, elongated pores for orthopedic tissue engineering applications. 
  • Understanding the elasticity of fibronectin fibrils: unfolding strengths of FN-III and GFP domains measured by single molecule force spectroscopy. 
  • Unified biophysical mechanism for cell-shape oscillations and cell ingression. 
  • Vascular hypertrophy is an early finding in essential hypertension and is related to arterial pressure waveform contour. 
  • Viscoelastic characteristics of muscle: passive stretching versus muscular contractions. 
  • Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes. 
  • Viscoelastic properties of the diastolic left ventricle in the conscious dog. 
  • Viscoelastic properties of zonal articular chondrocytes measured by atomic force microscopy. 
  • Vortex formation time is not an index of ventricular function. 
  • Water permeability of aquaporin-4 channel depends on bilayer composition, thickness, and elasticity. 
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  Keywords of People

  • Craig, Stephen L, William T. Miller Distinguished Professor of Chemistry, Duke University Energy Initiative
  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
  • Gall, Ken, Professor in the Department of Mechanical Engineering and Materials Science, Duke Innovation & Entrepreneurship
  • Nightingale, Kathryn Radabaugh, Theo Pilkington Distinguished Professor of Biomedical Engineering, Biomedical Engineering
  • Ridley, David Blaine, Professor of the Practice of Business Adminstration, Duke Science & Society
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering
  • Virgin, Lawrence N., Professor of Mechanical Engineering and Materials Science, Civil and Environmental Engineering
  • Zhong, Pei, Professor in the Department of Mechanical Engineering and Materials Science, Mechanical Engineering and Materials Science