Electron Transport

• 

  Subject Areas on Research

  • A bioenergetic profile of non-transformed fibroblasts uncovers a link between death-resistance and enhanced spare respiratory capacity. 
  • A hot oxidant, 3-NO2Y122 radical, unmasks conformational gating in ribonucleotide reductase. 
  • A new era for electron bifurcation. 
  • Acentric 2-D ensembles of D-br-A electron-transfer chromophores via vectorial orientation within amphiphilic n-helix bundle peptides for photovoltaic device applications. 
  • Amphiphilic four-helix bundle peptides designed for light-induced electron transfer across a soft interface. 
  • Assessing Possible Mechanisms of Micrometer-Scale Electron Transfer in Heme-Free Geobacter sulfurreducens Pili. 
  • Bacterial photosynthesis in surface waters of the open ocean. 
  • Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. 
  • Biochemistry and theory of proton-coupled electron transfer. 
  • Biochemistry. Photosynthesis from the protein's perspective. 
  • Biological charge transfer via flickering resonance. 
  • Breaking the simple proportionality between molecular conductances and charge transfer rates. 
  • Capacitive detection of glucose using molecularly imprinted polymers. 
  • Carbon monoxide-cytochrome interactions in the brain of the fluorocarbon-perfused rat. 
  • Cerebral mitochondrial metabolism in early Parkinson's disease. 
  • Charge Transport across DNA-Based Three-Way Junctions. 
  • Charge transfer in dynamical biosystems, or the treachery of (static) images. 
  • Cofactor Dynamics Couples the Protein Surface to the Heme in Cytochrome c , Facilitating Electron Transfer. 
  • Compartmentalized nitrosation and nitration in mitochondria. 
  • Conformation change of horseradish peroxidase in lipid membrane. 
  • Conformationally averaged score functions for electronic propagation in proteins. 
  • Constraints on physiological function associated with branch architecture and wood density in tropical forest trees. 
  • Control of electron transfer in nitrogenase. 
  • Correlated particle transport enables biological free energy transduction. 
  • Coupling coherence distinguishes structure sensitivity in protein electron transfer. 
  • Current saturation in submicrometer graphene transistors with thin gate dielectric: experiment, simulation, and theory. 
  • DNA: wire or insulator? 
  • Design and synthesis of manganese porphyrins with tailored lipophilicity: investigation of redox properties and superoxide dismutase activity. 
  • Design of a ruthenium-labeled cytochrome c derivative to study electron transfer with the cytochrome bc1 complex. 
  • Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate. 
  • Detection of necrosis by release of lactate dehydrogenase activity. 
  • Direct electron transfer between hemoglobin and a glassy carbon electrode facilitated by lipid-protected gold nanoparticles. 
  • Direct evaluation of electronic coupling mediated by hydrogen bonds: implications for biological electron transfer. 
  • Distance-independent charge recombination kinetics in cytochrome c-cytochrome c peroxidase complexes: compensating changes in the electronic coupling and reorganization energies. 
  • Dopamine Metabolism May Have Unexpected Benefits for Mitochondrial Energy Production. 
  • Early development of near-infrared spectroscopy at Duke University. 
  • Editorial overview: Biological pathways for electrons, protons and photo-excitations. 
  • Effect of backbone flexibility on charge transfer rates in peptide nucleic acid duplexes. 
  • Effect of famoxadone on photoinduced electron transfer between the iron-sulfur center and cytochrome c1 in the cytochrome bc1 complex. 
  • Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. 
  • Effects of phenylamide herbicides on the physical properties of phosphatidylcholine membranes. 
  • Electron acceptor function of O2 in radical N-demethylation reactions catalyzed by hemeproteins. 
  • Electron transfer characteristics of 2'-deoxy-2'-fluoro-arabinonucleic acid, a nucleic acid with enhanced chemical stability. 
  • Electron transfer in the photosynthetic reaction center: mechanistic implications of mutagenesis studies. 
  • Electron transfer mechanisms. 
  • Electron-tunneling pathways in proteins. 
  • Engineering opposite electronic polarization of singlet and triplet states increases the yield of high-energy photoproducts. 
  • Essential role of conserved arginine 160 in intramolecular electron transfer in human sulfite oxidase. 
  • Evidence for a near-resonant charge transfer mechanism for double-stranded peptide nucleic acid. 
  • Expert consensus document: Mitochondrial function as a therapeutic target in heart failure. 
  • Exploring biological electron transfer pathway dynamics with the Pathways plugin for VMD. 
  • Flavin interaction in NADPH-sulfite reductase. 
  • Fluctuations in biological and bioinspired electron-transfer reactions. 
  • From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans. 
  • Full-electron ligand-to-ligand charge transfer in a compact Re(I) complex. 
  • Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer. 
  • Functional studies on crosslinked bovine cytochrome c oxidase. 
  • Functions of cytochrome c in regulation of electron transfer and protein folding. 
  • Gene up-regulation in heart during mammalian hibernation. 
  • Generalized Mulliken-Hush analysis of electronic coupling interactions in compressed pi-stacked porphyrin-bridge-quinone systems. 
  • Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase. 
  • HEPATIC ALDEHYDE OXIDASE. II. DIFFERENTIAL INHIBITION OF ELECTRON TRANSFER TO VARIOUS ELECTRON ACCEPTORS. 
  • Heme-copper oxidases use tunneling pathways. 
  • Hepatic sulfite oxidase. Congruency in mitochondria of prosthetic groups and activity. 
  • Implausibility of the vibrational theory of olfaction. 
  • Inter- and intra-molecular electron transfer in the cytochrome bc(1) complex. 
  • Interfacial hydration, dynamics and electron transfer: multi-scale ET modeling of the transient [myoglobin, cytochrome b5] complex. 
  • Interference between Molecular and Photon Field-Mediated Electron Transfer Coupling Pathways in Cavities. 
  • Internal electron transfer between hemes and Cu(II) bound at cysteine beta93 promotes methemoglobin reduction by carbon monoxide. 
  • Intraprotein electron transfer in inducible nitric oxide synthase holoenzyme. 
  • Long-range electron transfer in myoglobin. 
  • Lucigenin: redox potential in aqueous media and redox cycling with O-(2) production. 
  • MIBG inhibits respiration: potential for radio- and hyperthermic sensitization. 
  • Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells. 
  • Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA. 
  • Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio. 
  • Microfluidic dielectrophoresis illuminates the relationship between microbial cell envelope polarizability and electrochemical activity. 
  • Mitochondria in sporadic amyotrophic lateral sclerosis. 
  • Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes. 
  • Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes. 
  • Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. 
  • Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis. 
  • Modulating unimolecular charge transfer by exciting bridge vibrations. 
  • Neuronal nitric-oxide synthase interaction with calmodulin-troponin C chimeras. 
  • Nitric oxide inhibits expression of cytochrome B in endotoxin-stimulated murine macrophages. 
  • Nonequivalence of the flavin adenine dinucleotide moieties of chicken liver xanthine dehydrogenase. 
  • Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease. 
  • Oxidation of molybdopterin in sulfite oxidase by ferricyanide. Effect on electron transfer activities. 
  • Oxidative metabolism in rat hepatocytes and mitochondria during sepsis. 
  • Oxygen-induced mitochondrial biogenesis in the rat hippocampus. 
  • Pathway analysis of protein electron-transfer reactions. 
  • Pathways, pathway tubes, pathway docking, and propagators in electron transfer proteins. 
  • Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins. 
  • Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. 
  • Photoinduced Electron Transfer Elicits a Change in the Static Dielectric Constant of a de Novo Designed Protein. 
  • Physical constraints on charge transport through bacterial nanowires. 
  • Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria. 
  • Protein dynamics and electron transfer: electronic decoherence and non-Condon effects. 
  • Protein electron transfer rates set by the bridging secondary and tertiary structure. 
  • Proton-coupled electron transfer. 
  • Purification and properties of chicken liver xanthine dehydrogenase. 
  • Purification and properties of xanthine dehydroganase from Micrococcus lactilyticus. 
  • Quasi-ohmic single molecule charge transport through highly conjugated meso-to-meso ethyne-bridged porphyrin wires. 
  • Rapid evolutionary innovation during an Archaean genetic expansion. 
  • Reactive oxygen species produced by liver mitochondria of rats in sepsis. 
  • Redox redux. 
  • Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. 3. The Escherichia coli hemoflavoprotein: catalytic parameters and the sequence of electron flow. 
  • Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. IV. The Escherichia coli hemoflavoprotein: subunit structure and dissociation into hemoprotein and flavoprotein components. 
  • Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite. 
  • Regulation of electron transport in hepatic mitochondria on acclimation of animals to heat stress. 
  • Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. 
  • Release of cytochrome c from liver mitochondria during permeability transition. 
  • Respiratory Capacity and Reserve Predict Cell Sensitivity to Mitochondria Inhibitors: Mechanism-Based Markers to Identify Metformin-Responsive Cancers. 
  • Role of conserved tyrosine 343 in intramolecular electron transfer in human sulfite oxidase. 
  • Seahorse Xfe 24 Extracellular Flux Analyzer-Based Analysis of Cellular Respiration in Caenorhabditis elegans. 
  • Siroheme: a new prosthetic group participating in six-electron reduction reactions catalyzed by both sulfite and nitrite reductases. 
  • Siroheme: a prosthetic group of the Neurospora crassa assimilatory nitrite reductase. 
  • Solvent dependence of intramolecular electron transfer in a helical oligoproline assembly. 
  • Steering electrons on moving pathways. 
  • Stoichiometries of protein-protein/DNA binding and conformational changes for the transition-state regulator AbrB measured by pseudo cell-size exclusion chromatography-mass spectrometry. 
  • Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex. 
  • Studies of aldehyde oxidase by electron paramagnetic resonance spectroscopy. I. Spectra at equilibrium states. 
  • Studies of aldehyde oxidase by electron paramagnetic resonance spectroscopy. II. Kinetic studies by rapid freezing. 
  • Studies on the dissociation of flavin adenine dinucleotide from metalloflavoproteins. 
  • Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity. 
  • THE ABSORPTION SPECTRA OF IRON-FLAVOPROTEINS. 
  • The 1.2 A structure of the human sulfite oxidase cytochrome b(5) domain. 
  • The nature of aqueous tunneling pathways between electron-transfer proteins. 
  • The single-molecule conductance and electrochemical electron-transfer rate are related by a power law. 
  • The site of the redox-linked proton pump in eukaryotic cytochrome c oxidases. 
  • Two-Electron Transfer Pathways. 
  • Vibrational control of electron-transfer reactions: a feasibility study for the fast coherent transfer regime. 
  • Voltage-induced long-range coherent electron transfer through organic molecules. 
  • Why Are DNA and Protein Electron Transfer So Different? 
  • Why Do Most Aromatics Fail to Support Hole Hopping in the Cytochrome c Peroxidase-Cytochrome c Complex? 
• 

  Keywords of People

  • Beratan, David N., R.J. Reynolds Distinguished Professor of Chemistry, Nicholas Institute-Energy Initiative