Subject Areas on Research
- A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents.
- Application of in vivo and in vitro pharmacokinetics for physiologically relevant drug exposure in a human tumor clonogenic cell assay.
- Phase I study of Datelliptium chloride, hydrochloride given by 24-h continuous intravenous infusion.
- Potential antiglioma activity of 9-hydroxy-2-N-methylellipticine as determined by pharmacological and human tumor clonogenic cell studies.