Endothelium, Lymphatic

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  Subject Areas on Research

  • A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. 
  • A high endothelial cell-derived chemokine induces rapid, efficient, and subset-selective arrest of rolling T lymphocytes on a reconstituted endothelial substrate. 
  • Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. 
  • Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. 
  • Genetic immunization with LYVE-1 cDNA yields function-blocking antibodies against native protein. 
  • Humoral immune responses in L-selectin-deficient mice. 
  • Mast cell modulation of the vascular and lymphatic endothelium. 
  • Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors. 
  • Schlemm's canal endothelia, lymphatic, or blood vasculature? 
  • Suppression of inflammatory corneal lymphangiogenesis by application of topical corticosteroids. 
  • The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules. 
  • The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. 
  • The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches. 
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  Keywords of People

  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology