Environmental Pollutants

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  Subject Areas on Research

  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces organ- specific differential gene expression in male Japanese medaka (Oryzias latipes). 
  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptotic cell death and cytochrome P4501A expression in developing Fundulus heteroclitus embryos. 
  • 20th Pollutant Responses in Marine Organisms (PRIMO 20): Global issues and fundamental mechanisms caused by pollutant stress in marine and freshwater organisms. 
  • In Vitro Metabolism of Isopropylated and tert -Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions. 
  • A Critical Time for Mercury Science to Inform Global Policy. 
  • A bioenergetics assay for studying the effects of environmental stressors on mitochondrial function in vivo in zebrafish larvae. 
  • A functional assay-based strategy for nanomaterial risk forecasting. 
  • A review of the environmental implications of in situ remediation by nanoscale zero valent iron (nZVI): Behavior, transport and impacts on microbial communities. 
  • Accumulation of atmospheric and sedimentary PCBs and toxaphene in a Lake Michigan food web. 
  • Accumulation of environmental contaminants in wood duck (Aix sponsa) eggs, with emphasis on polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans. 
  • Activating PKC-β1 at the blood-brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS. 
  • Adaptation to metals in widespread and endemic plants. 
  • Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells. 
  • Alcohol, drugs, caffeine, tobacco, and environmental contaminant exposure: reproductive health consequences and clinical implications. 
  • Amazon forests capture high levels of atmospheric mercury pollution from artisanal gold mining. 
  • An approach to the development of quantitative models to assess the effects of exposure to environmentally relevant levels of endocrine disruptors on homeostasis in adults. 
  • An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. 
  • Analysis of engineered nanomaterials in complex matrices (environment and biota): general considerations and conceptual case studies. 
  • Analysis of nonylphenol and nonylphenol ethoxylates in environmental samples by mixed-mode high-performance liquid chromatography-electrospray mass spectrometry. 
  • Antagonistic Growth Effects of Mercury and Selenium in Caenorhabditis elegans Are Chemical-Species-Dependent and Do Not Depend on Internal Hg/Se Ratios. 
  • Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses. 
  • Applications and societal benefits of plastics. 
  • Assessing the risks of manufactured nanomaterials. 
  • Assessment of emerging polar organic pollutants linked to contaminant pathways within an urban estuary using non-targeted analysis. 
  • Association between triclocarban and triclosan exposures and the risks of type 2 diabetes mellitus and impaired glucose tolerance in the National Health and Nutrition Examination Survey (NHANES 2013-2014). 
  • Association of environmental exposure to heavy metals and eczema in US population: Analysis of blood cadmium, lead, and mercury. 
  • Associations between brominated flame retardants in house dust and hormone levels in men. 
  • Associations between flame retardant applications in furniture foam, house dust levels, and residents' serum levels. 
  • Associations of birth outcomes with maternal polybrominated diphenyl ethers and thyroid hormones during pregnancy. 
  • BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells. 
  • Benthic and pelagic pathways of methylmercury bioaccumulation in estuarine food webs of the northeast United States. 
  • Biomonitoring of metals and trace elements in urine of central Ethiopian populations. 
  • Biotransformation of HBCD in biological systems can confound temporal-trend studies. 
  • Boron and strontium isotopic characterization of coal combustion residuals: validation of new environmental tracers. 
  • Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes. 
  • Brominated and chlorinated flame retardants in San Francisco Bay sediments and wildlife. 
  • Brominated flame retardants in breast milk and behavioural and cognitive development at 36 months. 
  • Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. 
  • Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. 
  • Caenorhabditis elegans as an emerging model system in environmental epigenetics. 
  • Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology. 
  • Certification of SRM 1589a PCBs, pesticides, PBDEs, and dioxins/furans in human serum. 
  • Characterization and Adaptation of Anaerobic Sludge Microbial Communities Exposed to Tetrabromobisphenol A. 
  • Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro. 
  • Children's exposure to phthalates and non-phthalate plasticizers in the home: The TESIE study. 
  • Chromosomally located gene fusions constructed in Acinetobacter sp. ADP1 for the detection of salicylate. 
  • Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor. 
  • Comprehensive environmental assessment: a meta-assessment approach. 
  • Concentrations of per- and polyfluoroalkyl substances (PFAS) in human placental tissues and associations with birth outcomes. 
  • Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) and their associations with human semen quality measurements. 
  • Correlation between selected environmental exposures and karyotype in acute myelocytic leukemia. 
  • Current-use flame retardants: Maternal exposure and neurodevelopment in children of the CHAMACOS cohort. 
  • Decreasing uncertainties in assessing environmental exposure, risk, and ecological implications of nanomaterials. 
  • Demographic and dietary risk factors in relation to urinary metabolites of organophosphate flame retardants in toddlers. 
  • Determination of glucuronide conjugates of hydroxyl triphenyl phosphate (OH-TPHP) metabolites in human urine and its use as a biomarker of TPHP exposure. 
  • Dietary intake polycyclic aromatic hydrocarbons (PAHs) and associated cancer risk in a cohort of Chinese urban adults: Inter- and intra-individual variability. 
  • Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary. 
  • Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats. 
  • Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults. 
  • EPA in the crosshairs. 
  • Early-life prevention of non-communicable diseases. 
  • Ecological significance of mitochondrial toxicants. 
  • Effect of size fractionation on the toxicity of amosite and Libby amphibole asbestos. 
  • Effects of humic substances on precipitation and aggregation of zinc sulfide nanoparticles 
  • Embryo toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the wood duck (Aix sponsa). 
  • Embryonic exposure to benzo[a]pyrene causes age-dependent behavioral alterations and long-term metabolic dysfunction in zebrafish. 
  • Emerging contaminants: presentations at the 2009 Toxicology and Risk Assessment Conference. 
  • Endocrine-disrupting chemicals and obesity risk: A review of recommendations for obesity prevention policies. 
  • Environmental Justice: the Economics of Race, Place, and Pollution. 
  • Environmental contaminants and body fat distribution. 
  • Environmental justice implications of reduced reporting requirements of the Toxics Release Inventory Burden Reduction Rule. 
  • Environmental occurrences, behavior, fate, and ecological effects of nanomaterials: an introduction to the special series. 
  • Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice. 
  • Evaluating daily exposure to polychlorinated biphenyls and polybrominated diphenyl ethers in fish oil supplements. 
  • Evaluating maternal exposure to an environmental per and polyfluoroalkyl substances (PFAS) mixture during pregnancy: Adverse maternal and fetoplacental effects in a New Zealand White (NZW) rabbit model. 
  • Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. 
  • Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review. 
  • Exposure of developing chicks to perfluorooctanoic acid induces defects in prehatch and early posthatch development. 
  • Exposure to Perfluoroalkyl Substances During Pregnancy and Fetal BDNF Level: A Prospective Cohort Study. 
  • Exposure to flame retardant chemicals and occurrence and severity of papillary thyroid cancer: A case-control study. 
  • Exposure to perfluorobutane sulfonate and perfluorooctanesulfonic acid disrupts the production of angiogenesis factors and stress responses in human placental syncytiotrophoblast. 
  • Exposure to polyfluoroalkyl chemicals and attention deficit/hyperactivity disorder in U.S. children 12-15 years of age. 
  • Express it in numbers: efforts to quantify engineered nanoparticles in environmental matrices advance. 
  • Flame retardant exposure among collegiate United States gymnasts. 
  • Flame retardants and their metabolites in the homes and urine of pregnant women residing in California (the CHAMACOS cohort). 
  • Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment. 
  • Gene expression in oogenesis and implications for transgenerational effects of environmental toxicants. 
  • Hazardous chemicals in synthetic turf materials and their bioaccessibility in digestive fluids. 
  • Heat map visualization of complex environmental and biomarker measurements. 
  • Heterogeneity of toxicant response: sources of human variability. 
  • Hydrophobic interactions increase attachment of gum arabic-and PVP-coated Ag nanoparticles to hydrophobic surfaces 
  • Hypospadias and halogenated organic pollutant levels in maternal mid-pregnancy serum samples. 
  • Impact of dust from multiple microenvironments and diet on PentaBDE body burden. 
  • Impacts of organic carbon availability and recipient bacteria characteristics on the potential for TOL plasmid genetic bioaugmentation in soil slurries. 
  • Importance of heterogeneous aggregation for NP fate in natural and engineered systems. 
  • Imprinted genes as potential genetic and epigenetic toxicologic targets. 
  • In vitro models reveal differences in the developmental neurotoxicity of an environmental polycylic aromatic hydrocarbon mixture compared to benzo[a]pyrene: Neuronotypic PC12 Cells and embryonic neural stem cells. 
  • Increases in ambient air pollutants during pregnancy are linked to increases in methylation of IL4, IL10, and IFNγ. 
  • Influence of amino acids cysteine and serine on aggregation kinetics of zinc and mercury sulfide colloids 
  • Influence of dissolved organic matter on the environmental fate of metals, nanoparticles, and colloids 
  • Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans 
  • Kinetics and inhibition of reductive dechlorination of trichloroethene, cis-1,2-dichloroethene and vinyl chloride in a continuously fed anaerobic biofilm reactor. 
  • Lactational exposure to polybrominated diphenyl ethers and its relation to social and emotional development among toddlers. 
  • Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. 
  • Linking Mitochondrial Dysfunction to Organismal and Population Health in the Context of Environmental Pollutants: Progress and Considerations for Mitochondrial Adverse Outcome Pathways. 
  • Linking PBDEs in house dust to consumer products using X-ray fluorescence. 
  • Maternal arsenic exposure, arsenic methylation efficiency, and birth outcomes in the Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Mexico. 
  • Measurement of DNA adducts using surface-enhanced Raman spectroscopy. 
  • Mercury hair levels and factors that influence exposure for residents of Huancavelica, Peru. 
  • Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic. 
  • Metabolism of PCBs by the deepwater sculpin (Myoxocephalus thompsoni). 
  • Mitochondria as a target of environmental toxicants 
  • Mitochondria, energetics, epigenetics, and cellular responses to stress. 
  • Mitochondrial Toxicity. 
  • Mitochondrial fusion, fission, and mitochondrial toxicity. 
  • Nanomaterials as possible contaminants: the fullerene example. 
  • Nanoscale metal-organic matter interactions. 
  • New techniques for imaging and analyzing lung tissue. 
  • Newspapers and newspaper ink contain agonists for the ah receptor. 
  • Non-neoplastic and neoplastic pleural endpoints following fiber exposure. 
  • Nonionic Ethoxylated Surfactants Induce Adipogenesis in 3T3-L1 Cells. 
  • Observing the human exposome as reflected in breath biomarkers: heat map data interpretation for environmental and intelligence research. 
  • Organophosphate flame-retardant metabolite concentrations and pregnancy loss among women conceiving with assisted reproductive technology. 
  • Outdoor urban nanomaterials: The emergence of a new, integrated, and critical field of study. 
  • PBDEs, methoxylated PBDEs and HBCDs in Japanese common squid (Todarodes pacificus) from Korean offshore waters. 
  • Perchlorate exposure in lactating women in an urban community in New Jersey. 
  • Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review. 
  • Perfluoroalkyl and polyfluoroalkyl substances and fetal thyroid hormone levels in umbilical cord blood among newborns by prelabor caesarean delivery. 
  • Perfluoroalkyl and polyfluroalkyl substances and maternal thyroid hormones in early pregnancy. 
  • Perfluoroalkyl substances exposure in early pregnancy and preterm birth in singleton pregnancies: a prospective cohort study. 
  • Persistent organic pollutants in two dolphin species with focus on toxaphene and polybrominated diphenyl ethers. 
  • Perspectives: the possible influence of assisted reproductive technologies on transgenerational reproductive effects of environmental endocrine disruptors. 
  • Physical activity attenuated the associations between ambient air pollutants and metabolic syndrome (MetS): A nationwide study across 28 provinces. 
  • Predictors and reproducibility of urinary organophosphate ester metabolite concentrations during pregnancy and associations with birth outcomes in an urban population. 
  • Predictors of mitochondrial DNA copy number and damage in a mercury-exposed rural Peruvian population near artisanal and small-scale gold mining: An exploratory study. 
  • Pregnancy exposure to common-detect organophosphate esters and phthalates and maternal thyroid function. 
  • Prenatal Phthalate Exposures and Childhood Fat Mass in a New York City Cohort. 
  • Prenatal exposure to organophosphate esters and cognitive development in young children in the Pregnancy, Infection, and Nutrition Study. 
  • Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances and the risk of hypertensive disorders of pregnancy. 
  • Prenatal phthalate exposures and executive function in preschool children. 
  • Quantitative mapping of trimethyltin injury in the rat brain using magnetic resonance histology. 
  • Recent advances in the analysis of polychlorinated biphenyls in environmental and biological media. 
  • Recent declines in PAH, PCB, and toxaphene levels in the northern Great Lakes as determined from high resolution sediment cores. 
  • Reducing Environmental Toxicity of Silver Nanoparticles through Shape Control. 
  • Residential mercury contamination in adobe brick homes in Huancavelica, Peru. 
  • Resolving mechanisms of toxicity while pursuing ecotoxicological relevance? 
  • Review of contaminant levels and effects in shorebirds: Knowledge gaps and conservation priorities. 
  • Role of the aryl hydrocarbon receptor in cell cycle regulation. 
  • Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity. 
  • Sea urchin embryos and larvae as biosensors for neurotoxicants. 
  • Serum cadmium levels in pancreatic cancer patients from the East Nile Delta region of Egypt. 
  • Serum levels of polybrominated diphenyl ethers (PBDEs) in foam recyclers and carpet installers working in the United States. 
  • Serum perfluoroalkyl acids (PFAAs) and associations with behavioral attributes. 
  • Silver exposure in developing zebrafish (Danio rerio): persistent effects on larval behavior and survival. 
  • Speciation Matters: Bioavailability of Silver and Silver Sulfide Nanoparticles to Alfalfa (Medicago sativa). 
  • Speciation and bioaccessibility of mercury in adobe bricks and dirt floors in Huancavelica, Peru. 
  • Sublethal effects of pentachlorophenol in abalone (Haliotis rufescens) veliger larvae as measured by (31)P-NMR. 
  • Synergistic embryotoxicity of polycyclic aromatic hydrocarbon aryl hydrocarbon receptor agonists with cytochrome P4501A inhibitors in Fundulus heteroclitus. 
  • Teratogenesis in Fundulus heteroclitus embryos exposed to a creosote-contaminated sediment extract and CYP1A inhibitors. 
  • The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions. 
  • The associations between environmental quality and preterm birth in the United States, 2000-2005: a cross-sectional analysis. 
  • The effect of non-fluoride factors on risk of dental fluorosis: evidence from rural populations of the Main Ethiopian Rift. 
  • The lightpipe luminoscope for monitoring occupational skin contamination. 
  • The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus). 
  • The relationship between early childhood blood lead levels and performance on end-of-grade tests. 
  • Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium. 
  • Toddler's behavior and its impacts on exposure to polybrominated diphenyl ethers. 
  • Toward identifying the next generation of superfund and hazardous waste site contaminants. 
  • Translational toxicology: a developmental focus for integrated research strategies. 
  • Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management. 
  • Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization. 
  • Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550. 
  • Use of non-mammalian alternative models for neurotoxicological study. 
  • Zebrafish developmental screening of the ToxCast™ Phase I chemical library. 
  • Zebrafish: as an integrative model for twenty-first century toxicity testing. 
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  Keywords of People

  • Al-Hegelan, Mashael, Associate Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • Ferguson, P. Lee, Associate Professor of Civil and Environmental Engineering, Civil and Environmental Engineering
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Hsu-Kim, Heileen, Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering
  • Jeuland, Marc A., Associate Professor in the Sanford School of Public Policy, Nicholas Institute-Energy Initiative
  • Richter, Daniel D., Professor in the Division of Earth and Climate Science, Environmental Sciences and Policy
  • Vengosh, Avner, Nicholas Distinguished Professor of Environmental Quality, Nicholas Institute-Energy Initiative