Eosinophils

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  Subject Areas on Research

  • 5-Oxo-eicosatetraenoate is a broadly active, eosinophil-selective stimulus for human granulocytes. 
  • A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues. 
  • Activation of 85 kDa PLA2 by eicosanoids in human neutrophils and eosinophils. 
  • Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust. 
  • Allergen-induced airway disease is mouse strain dependent. 
  • An acoustofluidic sputum liquefier. 
  • Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis. 
  • Analysis of the human thymic perivascular space during aging. 
  • Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways. 
  • Bacterial biogeography of adult airways in atopic asthma. 
  • Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease. 
  • Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease. 
  • CD40 mediated activation of gingival and periodontal ligament fibroblasts. 
  • Changing Paradigms in the Treatment of Severe Asthma: The Role of Biologic Therapies. 
  • Characterization of skin cytokines in bullous pemphigoid and pemphigus vulgaris. 
  • Clinical significance of eosinophils in suspicious or borderline renal allograft biopsies. 
  • Comparison of human eosinophil and neutrophil adhesion to endothelial cells under nonstatic conditions. Role of L-selectin. 
  • Cryptococcus neoformans hyperfilamentous strain is hypervirulent in a murine model of cryptococcal meningoencephalitis. 
  • Cytologic findings in vitreous fluids. Analysis of 74 specimens. 
  • Diagnostic criteria for degenerative, inflammatory, proliferative nonneoplastic and neoplastic liver lesions in medaka (Oryzias latipes): consensus of a National Toxicology Program Pathology Working Group. 
  • Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. 
  • Eosinophil chemotaxis and anterior uveitis from topical dimaprit and nordimaprit. 
  • Eosinophil-associated lung diseases. A cry for surfactant proteins A and D help? 
  • Eosinophils Mediate Tissue Injury in the Autoimmune Skin Disease Bullous Pemphigoid. 
  • Eosinophils alter colonic epithelial barrier function: role for major basic protein. 
  • Eosinophils in corneas removed by penetrating keratoplasty. 
  • Esophagitis: a frequent consequence of gastroesophageal reflux in infancy. 
  • Extensive surface phenotyping of alveolar macrophages in interstitial lung disease. 
  • Functional inactivation and structural disruption of human alpha 2-macroglobulin by neutrophils and eosinophils. 
  • Gastroesophageal reflux and esophagitis in infants and children. 
  • Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model. 
  • Human eosinophil adherence to serum-treated sepharose: granule-associated enzyme release and requirement for activation of the alternative complement pathway. 
  • IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils. 
  • Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils. 
  • Immunization and challenge with toluene diisocyanate decrease tachykinin and calcitonin gene-related peptide immunoreactivity in guinea pig central airways. 
  • Immunoglobulin and complement receptors on human eosinophils and their role in cellular adherence to schistosomules. 
  • Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromes. 
  • Increased surfactant protein D in rat airway goblet and Clara cells during ovalbumin-induced allergic airway inflammation. 
  • Inflammatory cell distribution within and along asthmatic airways. 
  • Inflammatory events in the blood and airways of guinea pigs immunized to toluene diisocyanate. 
  • Influence of exposure to tobacco cigarette smoke on the eosinophil count in the nasal mucosa of young patients with perennial allergic rhinitis. 
  • Intracranial aneurysm secondary to mycotic orbital and sinus infection. Report of a case implicating penicillium as an opportunistic fungus. 
  • Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. 
  • Medusa cells: cytostructure and cytochemistry of amoeboid eosinophils with pseudopod-like processes. 
  • Medusa cells: the morphology and cytochemistry of common amoeboid variants of eosinophils. 
  • Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease. 
  • Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. 
  • Multicenter clinical trials on a novel polyherbal formulation in allergic rhinitis. 
  • Neuromuscular ultrasound findings in eosinophilic fasciitis: A case series and literature review. 
  • Neutrophilic figurate erythema of infancy: A diagnostic challenge. 
  • Obesity's effect on asthma extends to diagnostic criteria. 
  • Ocular allergy modulation to hi-dose antigen sensitization is a Treg-dependent process. 
  • Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease. 
  • Pharmacokinetics and pharmacodynamics of SB-240563, a humanized monoclonal antibody directed to human interleukin-5, in monkeys. 
  • Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice. 
  • Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys. 
  • Pregnancy and adrenocortical function; endocrine studies of pregnancy occurring in two adrenal-deficient women. 
  • Quantitative laser scanning confocal autofluorescence microscopy of normal, premalignant, and malignant colonic tissues. 
  • Rapid and Consistent Improvements in Morning PEF in Patients with Severe Eosinophilic Asthma Treated with Mepolizumab. 
  • Role of the eosinophil count in discriminating the severity of community-acquired pneumonia in HIV-infected patients. 
  • Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. 
  • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 
  • Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids. 
  • Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs. 
  • The cutaneous manifestations of atypical complete DiGeorge syndrome: a histopathologic and immunohistochemical study. 
  • The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace. 
  • The immunological axis in heart failure: importance of the leukocyte differential. 
  • The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation. 
  • Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. 
  • c-FLIP protects eosinophils from TNF-α-mediated cell death in vivo. 
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  Keywords of People

  • Gunn, Michael Dee, Professor of Medicine, Immunology