Erythropoiesis
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Subject Areas on Research
- Abnormal lipid composition of the red cell membrane in congenital dyserythropoietic anemia type II (HEMPAS).
- Accumulation of glycolipids containing N-acetylglucosamine in erythrocyte stroma of patients with congenital dyserythropoietic anemia type II (HEMPAS).
- Adducin in erythrocyte precursor cells of rats and humans: expression and compartmentalization.
- Anemia of prematurity.
- Benefits of early intervention with erythropoiesis- stimulating proteins in chemotherapy-induced anemia.
- Co-operative signalling mechanisms required for erythroid precursor expansion in response to erythropoietin and stem cell factor.
- Decay-accelerating factor is present on paroxysmal nocturnal hemoglobinuria erythroid progenitors and lost during erythropoiesis in vitro.
- Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.
- Effects of graded doses of testosterone on erythropoiesis in healthy young and older men.
- Erythrocyte adhesion receptors: blood group antigens and related molecules.
- Erythropoiesis-stimulating protein support and survival.
- Erythropoietin receptor signals both proliferation and erythroid-specific differentiation.
- Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.
- Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2.
- Familial polycythemia due to truncations of the erythropoietin receptor.
- Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis.
- Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage.
- Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis.
- Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.
- High levels of human gamma-globin gene expression in adult mice carrying a transgene of deletion-type hereditary persistence of fetal hemoglobin.
- Identification of a human heme exporter that is essential for erythropoiesis.
- Inducers of Friend leukaemic cell differentiation in vitro--effects of in vivo administration.
- Inverse relationship between splenomegaly and stem cell compartment size in mice treated with nitrogen mustard.
- Ion fluxes and differentiation in transformed cell lines.
- Nitric oxide, malaria, and anemia: inverse relationship between nitric oxide production and hemoglobin concentration in asymptomatic, malaria-exposed children.
- Phase I study of pharmacological and immunological effects of human lymphoblastoid interferon given to patients with cancer.
- Physicochemical characteristics and biological effects of nickel oxides.
- Polycythemia vera erythroid precursors exhibit increased proliferation and apoptosis resistance associated with abnormal RAS and PI3K pathway activation.
- Prospective evaluation of the association between cardiac troponin T and markers of disturbed erythropoiesis in patients with heart failure.
- Purification and characterization of the yeast-expressed erythropoietin mutant Epo (R103A), a specific inhibitor of human primary hematopoietic cell erythropoiesis.
- RBC transfusions in paroxysmal nocturnal hemoglobinuria.
- Receptors that induce erythroid differentiation of Ba/F3 cells: structural requirements and effect on STAT5 binding.
- Selective erythroid replacement in murine beta-thalassemia using fetal hematopoietic stem cells.
- Sequential activation of splenic nuclear RNA polymerases by erythropoietin.
- Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver.
- The in vitro growth of murine high proliferative potential-colony forming cells is not enhanced by growth in a low oxygen atmosphere.
- The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.
- Transferrin receptor is necessary for development of erythrocytes and the nervous system.
- Type II congenital dyserythropoietic anemia.
- Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure.
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Keywords of People
- O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology, Medicine, Clinical Pharmacology