Escherichia coli

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  Subject Areas on Research

  • 2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor. 
  • 5'-Terminal nucleotide sequence of Escherichia coli lactose repressor mRNA: features of translational initiation and reinitiation sites. 
  • 5-Azacytidine induced methyltransferase-DNA adducts block DNA replication in vivo. 
  • 50 million years of genomic stasis in endosymbiotic bacteria. 
  • A 'Semi-Protected Oligonucleotide Recombination' Assay for DNA Mismatch Repair in vivo Suggests Different Modes of Repair for Lagging Strand Mismatches. 
  • A 13-kilodalton maize mitochondrial protein in E. coli confers sensitivity to Bipolaris maydis toxin. 
  • A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis. 
  • A 9-Year retrospective review of antibiotic cycling in a surgical intensive care unit. 
  • A bacterial selection for the directed evolution of pyruvate aldolases. 
  • A bacteriophage model system for studying topoisomerase inhibitors. 
  • A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria. 
  • A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase. 
  • A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon. 
  • A comparative study of the mannose-resistant and mannose-sensitive haemagglutinins of Escherichia coli isolated from urinary tract infections. 
  • A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics. 
  • A defective phage system reveals bacteriophage T4 replication origins that coincide with recombination hot spots. 
  • A genomics approach to improve the analysis and design of strain selections. 
  • A graphical method for analyzing distance restraints using residual dipolar couplings for structure determination of symmetric protein homo-oligomers. 
  • A highly sensitive and specific enzyme-linked immunosorbent assay of antibodies to hepatitis C virus. 
  • A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. 
  • A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada. 
  • A modified procedure for fast purification of T7 RNA polymerase. 
  • A multicenter comparative trial of three-day norfloxacin vs ten-day sulfamethoxazole and trimethoprim for the treatment of uncomplicated urinary tract infections. 
  • A noisy linear map underlies oscillations in cell size and gene expression in bacteria. 
  • A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells. 
  • A novel thermostable branching enzyme from an extremely thermophilic bacterial species, Rhodothermus obamensis. 
  • A nucleotide change in the anticodon of an Escherichia coli serine transfer RNA results in supD-amber suppression. 
  • A programmable microenvironment for cellular studies via microfluidics-generated double emulsions. 
  • A quantitative analysis of C3 binding to O-antigen capsule, lipopolysaccharide, and outer membrane protein of E. coli 0111B4. 
  • A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus. 
  • A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus. 
  • A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. 
  • A single base substitution in the variable pocket of yeast tRNA(Arg) eliminates species-specific aminoacylation. 
  • A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes. 
  • A study of the binding of thiamine diphosphate and thiochrome diphosphate to the pyruvate dehydrogenase multienzyme complex. 
  • A sulfurtransferase is required in the transfer of cysteine sulfur in the in vitro synthesis of molybdopterin from precursor Z in Escherichia coli. 
  • A surface of Escherichia coli sigma 70 required for promoter function and antitermination by phage lambda Q protein. 
  • A synthetic Escherichia coli predator-prey ecosystem. 
  • A system of transposon mutagenesis for bacteriophage T4. 
  • A three-dimensional ParF meshwork assembles through the nucleoid to mediate plasmid segregation. 
  • A whole more than the sum of its synthetic parts. 
  • ADPase activity of recombinantly expressed thermotolerant ATPases may be caused by copurification of adenylate kinase of Escherichia coli. 
  • ATP hydrolysis by a CFTR domain: pharmacology and effects of G551D mutation. 
  • Accelerated deamination of cytosine residues in UV-induced cyclobutane pyrimidine dimers leads to CC-->TT transitions. 
  • Activated conformers of Escherichia coli sulfite reductase heme protein subunit. 
  • Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis. 
  • Addressing biological uncertainties in engineering gene circuits. 
  • Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study. 
  • Adherence of streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells. 
  • Agar shake tube technique for simultaneous determination of aerobic and anaerobic susceptibility to antibiotics. 
  • Alkaline low spin form of sulfite reductase hemeprotein subunit. 
  • Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli. 
  • Allergic reactions to E. coli L-asparaginase do not affect outcome in childhood B-precursor acute lymphoblastic leukemia: a Children's Oncology Group Study. 
  • Alterations in reticulo-endothelial functions as produced by the administration of bacterial toxins. 
  • Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect. 
  • Amphiphilic cationic Zn-porphyrins with high photodynamic antimicrobial activity. 
  • An Escherichia coli mutant defective in lipid export. 
  • An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation. 
  • An active site tyrosine influences the ability of the dimethyl sulfoxide reductase family of molybdopterin enzymes to reduce S-oxides. 
  • An antitumor drug-induced topoisomerase cleavage complex blocks a bacteriophage T4 replication fork in vivo. 
  • An equilibrium binding study of the interaction of aspartate transcarbamylase with cytidine 5'-triphosphate and adenosine 5'-triphosphate. 
  • An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A. 
  • An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli. 
  • Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor. 
  • Analysis of the protein products encoded by variant glucokinase transcripts via expression in bacteria. 
  • Antiadhesive properties of a quaternary structure-specific hybridoma antibody against type 1 fimbriae of Escherichia coli. 
  • Antibacterial activity of fullerene water suspensions (nC60) is not due to ROS-mediated damage. 
  • Antibiotic and antimalarial quinones from fungus-growing ant-associated Pseudonocardia sp. 
  • Antibiotic prophylaxis and non-group B streptococcal neonatal sepsis. 
  • Antibiotic resistance in urinary isolates of Escherichia coli from college women with urinary tract infections. 
  • Antibiotics as a selective driver for conjugation dynamics. 
  • Antitermination by bacteriophage lambda Q protein. 
  • Apparent cooperative assembly of the bacterial cell division protein FtsZ demonstrated by isothermal titration calorimetry. 
  • Appropriate expression of filamentous phage f1 DNA replication genes II and X requires RNase E-dependent processing and separate mRNAs. 
  • Arachidonate and related unsaturated fatty acids selectively inactivate the guanine nucleotide-binding regulatory protein, Gz. 
  • Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. 
  • Assembly and molecular activities of the MutS tetramer. 
  • Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins. 
  • Assembly dynamics of Mycobacterium tuberculosis FtsZ. 
  • Assembly of a chemically synthesized peptide of Escherichia coli type 1 fimbriae into fimbria-like antigenic structures. 
  • Assignment of 1H, 13C and 15N backbone resonances of Escherichia coli LpxC bound to L-161,240. 
  • Association of molybdopterin guanine dinucleotide with Escherichia coli dimethyl sulfoxide reductase: effect of tungstate and a mob mutation. 
  • Association of the viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids. 
  • Atomic force microscopy captures MutS tetramers initiating DNA mismatch repair. 
  • Atomic force microscopy captures folded ribosome bound nascent chains. 
  • Atomic force microscopy captures the initiation of methyl-directed DNA mismatch repair. 
  • Avicinylation (thioesterification): a protein modification that can regulate the response to oxidative and nitrosative stress. 
  • Bacteremia in sickle hemoglobinopathies. 
  • Bacteria-host cell interaction mediated by cellular cholesterol/glycolipid-enriched microdomains. 
  • Bacterial adherence. Adhesin receptor-mediated attachment of pathogenic bacteria to mucosal surfaces. 
  • Bacterial and fungal contamination of human fetal liver collected transvaginally for hematopoietic stem cell transplantation. 
  • Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers. 
  • Bacterial colonization of intravenous catheter materials in vitro and in vivo. 
  • Bacterial conversion of folinic acid is required for antifolate resistance. 
  • Bacterial penetration of bladder epithelium through lipid rafts. 
  • Bacterial penetration of the mucosal barrier by targeting lipid rafts. 
  • Bacterial priming increases lung injury in gram-negative sepsis. 
  • Bacterial surface association of heat-labile enterotoxin through lipopolysaccharide after secretion via the general secretory pathway. 
  • Bacterial uropathogens and antibiotic susceptibility of positive urine cultures in women with pelvic organ prolapse and urinary incontinence. 
  • Bactericidal agents generated by the peroxidase-catalyzed oxidation of para-hydroquinones. 
  • Bactericidal and opsonic properties of C4-deficient guinea pig serum. 
  • Bacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coli. 
  • Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair and the regulation of DNA replication origins. 
  • Bacteriophage T4 helicase loader protein gp59 functions as gatekeeper in origin-dependent replication in vivo. 
  • Bacteriophage T4 initiates bidirectional DNA replication through a two-step process. 
  • Binding of bacteria to mucosal surfaces. 
  • Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site. 
  • Biochemical and structural insights into bacterial organelle form and biogenesis. 
  • Biochemical role of the Cryptococcus neoformans ADE2 protein in fungal de novo purine biosynthesis. 
  • Biomimetic anchors for antifouling and antibacterial polymer brushes on stainless steel. 
  • Biosynthesis and processing of the molybdenum cofactors. 
  • Biosynthesis of undecaprenyl phosphate-galactosamine and undecaprenyl phosphate-glucose in Francisella novicida. 
  • Biotinylated tags for recovery and characterization of ribonucleoprotein complexes. 
  • Bisulfite induces tandem double CC-->TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination. 
  • Bleomycin induces the hsp 70 heat shock promoter in cultured cells. 
  • Bloodstream infections in community hospitals in the 21st century: a multicenter cohort study. 
  • Boranophosphates support the RNase H cleavage of polyribonucleotides. 
  • Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. 
  • C-Terminal glycine-gated radical initiation by GTP 3',8-cyclase in the molybdenum cofactor biosynthesis. 
  • C-terminally truncated derivatives of Escherichia coli Hfq are proficient in riboregulation. 
  • CD14-dependent mechanism for endotoxin-mediated nitric oxide synthesis in murine macrophages. 
  • Calmodulin mediates Ca2+ sensitivity of sodium channels. 
  • Can Dissipative Properties of Single Molecules Be Extracted from a Force Spectroscopy Experiment? 
  • Carbon dioxide capture using Escherichia coli expressing carbonic anhydrase in a foam bioreactor. 
  • Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance. 
  • Catalytic properties of the HhaII restriction endonuclease. 
  • Cathepsin B is up-regulated and mediates extracellular matrix degradation in trabecular meshwork cells following phagocytic challenge. 
  • Cell- and heparin-binding domains of the hexabrachion arm identified by tenascin expression proteins. 
  • Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA. 
  • Changes in streptonigrin lethality during adaptation of Escherichia coli to picolinic acid. Correlation with intracellular picolinate and iron uptake. 
  • Chaperone-assisted assembly and molecular architecture of adhesive pili. 
  • Characterisation of PduS, the pdu metabolosome corrin reductase, and evidence of substructural organisation within the bacterial microcompartment. 
  • Characterization and crystal structure of Escherichia coli KDPGal aldolase. 
  • Characterization of a putative periplasmic transport system for octopine accumulation encoded by Agrobacterium tumefaciens Ti plasmid pTiA6. 
  • Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli. 
  • Characterization of human interferon-gamma and human interleukin-2 from recombinant mammalian cell lines and peripheral blood lymphocytes. 
  • Characterization of key residues in the subdomain encoded by exons 8 and 9 of human inducible nitric oxide synthase: a critical role for Asp-280 in substrate binding and subunit interactions. 
  • Characterization of molybdenum cofactor from Escherichia coli. 
  • Characterization of the cysJIH regions of Salmonella typhimurium and Escherichia coli B. DNA sequences of cysI and cysH and a model for the siroheme-Fe4S4 active center of sulfite reductase hemoprotein based on amino acid homology with spinach nitrite reductase. 
  • Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase. 
  • Characterization of two mRNA-rRNA complexes implicated in the initiation of protein biosynthesis. 
  • Characterizing the use of perdeuteration in NMR studies of large proteins: 13C, 15N and 1H assignments of human carbonic anhydrase II. 
  • Chasing acyl carrier protein through a catalytic cycle of lipid A production. 
  • Circular ribozymes generated in Escherichia coli using group I self-splicing permuted intron-exon sequences. 
  • Circularizing ribozymes and decoy-competitors by autocatalytic splicing in vitro and in vivo. 
  • Classification of polyhedral shapes from individual anisotropically resolved cryo-electron tomography reconstructions. 
  • Cloning and expression of the yeast plasma membrane ATPase in Escherichia coli. 
  • Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase. 
  • Co-option of endocytic functions of cellular caveolae by pathogens. 
  • Collective Space-Sensing Coordinates Pattern Scaling in Engineered Bacteria. 
  • Comparative pharmacokinetic studies of three asparaginase preparations. 
  • Comparing serologic response against enteric pathogens with reported diarrhea to assess the impact of improved household drinking water quality. 
  • Comparison of the Euglena chloroplast protein synthesizing system with those of prokaryotes and eukaryotes. 
  • Comparison of the functional differences for the homologous residues within the carboxy phosphate and carbamate domains of carbamoyl phosphate synthetase. 
  • Competing Pathways and Multiple Folding Nuclei in a Large Multidomain Protein, Luciferase. 
  • Complementation of SOD-deficient Escherichia coli by manganese porphyrin mimics of superoxide dismutase activity. 
  • Complex environmental drivers of immunity and resistance in malaria mosquitoes. 
  • Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes. 
  • Computational design of a biologically active enzyme. 
  • Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. 
  • Conserved immunoglobulin-like features in a family of periplasmic pilus chaperones in bacteria. 
  • Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells. 
  • Construction of a catalytically active iron superoxide dismutase by rational protein design. 
  • Construction of new ligand binding sites in proteins of known structure. I. Computer-aided modeling of sites with pre-defined geometry. 
  • Construction of new ligand binding sites in proteins of known structure. II. Grafting of a buried transition metal binding site into Escherichia coli thioredoxin. 
  • Contamination of weaning foods and transmission of enterotoxigenic Escherichia coli diarrhoea in children in rural Bangladesh. 
  • Contribution of mast cells to bacterial clearance and their proliferation during experimental cystitis induced by type 1 fimbriated E. coli. 
  • Contribution of urinary tract infection to the burden of febrile illnesses in young children in rural Kenya. 
  • Contributions of the classical and alternate complement pathways to the biological effects of endotoxin. 
  • Controlled evaluation of 5 versus 10 milliliters of blood cultured in aerobic BacT/Alert blood culture bottles. 
  • Converting a maltose receptor into a nascent binuclear copper oxygenase by computational design. 
  • Coupling spatial segregation with synthetic circuits to control bacterial survival. 
  • Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: a soluble, secreted CD30 homologue. 
  • Cross-linking of the cms-T maize mitochondrial pore-forming protein URF13 by N,N'-dicyclohexylcarbodiimide and its effect on URF13 sensitivity to fungal toxins. 
  • Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism. 
  • Crystal structure of activated CheY. Comparison with other activated receiver domains. 
  • Crystal structure of an activated response regulator bound to its target. 
  • Crystal structure of molybdopterin synthase and its evolutionary relationship to ubiquitin activation. 
  • Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli. 
  • Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin. 
  • Crystal structure of the transcription activator BmrR bound to DNA and a drug. 
  • Crystalline arrays of the Escherichia coli sn-glycerol-3-phosphate acyltransferase, an integral membrane protein. 
  • Crystallization and preliminary X-ray analysis of the ATPase domain of the σ(54)-dependent transcription activator NtrC1 from Aquifex aeolicus bound to the ATP analog ADP-BeFx. 
  • Crystallization and preliminary X-ray crystallographic studies of glutaredoxin 2 from Saccharomyces cerevisiae in different oxidation states. 
  • Crystallization and preliminary x-ray studies of NADPH-cytochrome P450 reductase. 
  • Cutaneous Burn Injury Modulates Urinary Antimicrobial Peptide Responses and the Urinary Microbiome. 
  • Cutting of M13mp7 phage DNA and excision of cloned single-stranded sequences by restriction endonucleases. 
  • Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells. 
  • Cyclin-binding motifs are essential for the function of p21CIP1. 
  • Cytosine deamination in mismatched base pairs. 
  • Cytoskeleton. Evolution in bacteria. 
  • DNA damage responses in prokaryotes: regulating gene expression, modulating growth patterns, and manipulating replication forks. 
  • DNA mismatch correction in a defined system. 
  • DNA mismatch correction. 
  • DNA nicks inflicted by restriction endonucleases are repaired by a RecA- and RecB-dependent pathway in Escherichia coli. 
  • DNA repair synthesis after x-irradiation in E. coli. 
  • Deletion of carboxy-terminal residues of murine granulocyte-macrophage colony-stimulating factor results in a loss of biologic activity and altered glycosylation. 
  • Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies. 
  • Detecting ultraviolet damage in single DNA molecules by atomic force microscopy. 
  • Detection of Escherichia coli enterotoxins in stools. 
  • Diarrhoea associated with heat-stable enterotoxin-producing strains of Escherichia coli. 
  • Differential and simultaneous adenosine di- and triphosphate binding by MutS. 
  • Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology. 
  • Differential expression of intracellular and secreted osteopontin isoforms by murine macrophages in response to toll-like receptor agonists. 
  • Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. 
  • Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma interferon production. 
  • Dimerization is required for the activity of the protein histidine kinase CheA that mediates signal transduction in bacterial chemotaxis. 
  • Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. 
  • Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate. 
  • Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide. 
  • Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates. 
  • Discovery of novel bacterial elongation condensing enzyme inhibitors by virtual screening. 
  • Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis. 
  • Discrimination of tRNALeu isoacceptors by the insertion mutant of Escherichia coli leucyl-tRNA synthetase. 
  • Disease due to enterotoxigenic Escherichia coli in Bangladeshi adults: clinical aspects and a controlled trial of tetracycline. 
  • Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase. 
  • Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity. 
  • Drug design from the cryptic inhibitor envelope. 
  • Drug detoxification dynamics explain the postantibiotic effect. 
  • DsdA (D-serine deaminase): a new heterologous MX cassette for gene disruption and selection in Saccharomyces cerevisiae. 
  • E. coli expression system for identifying folding mutations of human adenosine deaminase. 
  • Early and late onset sepsis in late preterm infants. 
  • Early onset neonatal sepsis: the burden of group B Streptococcal and E. coli disease continues. 
  • EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme. 
  • Editorial: Toxigenic turista. 
  • Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation. 
  • Effect of cysteine residues on the activity of arginyl-tRNA synthetase from Escherichia coli. 
  • Effect of point-of-use disinfection, flocculation and combined flocculation-disinfection on drinking water quality in western Kenya. 
  • Effect of protein fusion on the transition temperature of an environmentally responsive elastin-like polypeptide: a role for surface hydrophobicity? 
  • Effect of sex on the induction of anti-DNA antibodies in normal mice immunized with bacterial DNA. 
  • Effect of trimethoprim-sulfamethoxazole prophylaxis on antimicrobial resistance of fecal Escherichia coli in HIV-infected patients in Tanzania. 
  • Effects of Escherichia coli physiology on growth of phage T7 in vivo and in silico. 
  • Effects of bacterial DNA on cytokine production by (NZB/NZW)F1 mice. 
  • Effects of fatty acid composition on the sensitivity of membrane functions to ethanol in Escherichia coli. 
  • Effects of granulocyte-macrophage colony stimulating factor produced in Chinese hamster ovary cells (regramostim), Escherichia coli (molgramostim) and yeast (sargramostim) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. 
  • Effects of high levels of DNA adenine methylation on methyl-directed mismatch repair in Escherichia coli. 
  • Effects of modulation of glycerol kinase expression on lipid and carbohydrate metabolism in human muscle cells. 
  • Elastin-like polypeptides as a purification tag for recombinant proteins. 
  • Elementary steps in the reaction mechanism of pyruvate dehydrogenase multienzyme complex from Escherichia coli: kinetics of flavin reduction. 
  • Elementary steps in the reaction mechanism of the alpha-ketoglutarate dehydrogenase multienzyme complex from Escherichia coli: kinetics of succinylation and desuccinylation. 
  • Elementary steps in the reaction mechanism of the pyruvate dehydrogenase multienzyme complex from Escherichia coli: kinetics of acetylation and deacetylation. 
  • Elongation by Escherichia coli RNA polymerase is blocked in vitro by a site-specific DNA binding protein. 
  • Emergence of extended-spectrum beta-lactamase-producing Escherichia coli in community hospitals throughout North Carolina: a harbinger of a wider problem in the United States? 
  • Emergent bistability by a growth-modulating positive feedback circuit. 
  • Emerging features of mRNA decay in bacteria. 
  • Endonuclease-independent DNA mismatch repair processes on the lagging strand. 
  • Endotoxin-mediated synthesis of nitric oxide is dependent on Gq protein signal transduction. 
  • Enhanced bactericidal activity of phagocytes from patients with chronic granulomatous disease in the presence of sulphisoxazole. 
  • Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder. 
  • Enteroinvasive Escherichia coli: a cause of bacteremia in patients with AIDS. 
  • Enterotoxigenic Escherichia coli and Reovirus-like agent in rural Bangladesh. 
  • Enterotoxigenic Escherichia coli diarrhoea: acquired immunity and transmission in an endemic area. 
  • Enterotoxigenic Escherichia coli secretes active heat-labile enterotoxin via outer membrane vesicles. 
  • Enterotoxigenic Escherichia coli vesicles target toxin delivery into mammalian cells. 
  • Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917. 
  • Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase. 
  • Enzyme-linked immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin. 
  • Epidemiologic assessment of the relevance of the so-called enteropathogenic serogroups of Escherichia coli in diarrhea. 
  • Epithelial cell adherence mediated by the enterotoxigenic Escherichia coli tia protein. 
  • Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine. 
  • Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia. 
  • Escherichia coli MoeA and MogA. Function in metal incorporation step of molybdenum cofactor biosynthesis. 
  • Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains. 
  • Escherichia coli global gene expression in urine from women with urinary tract infection. 
  • Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. 
  • Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs. 
  • Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth. 
  • Escherichia coli phage T4 topoisomerase. 
  • Escherichia coli produces linoleic acid during late stationary phase. 
  • Escherichia coli serotypes and diarrhea. 
  • Euglena gracilis chloroplast small subunit rRNA. Sequence and base pairing potential of the 3' terminus, cleavage by colicin E3. 
  • Evaluation of an antimicrobial-impregnated continuous ambulatory peritoneal dialysis catheter for infection control in rats. 
  • Evaluation of on-site wastewater system Escherichia coli contributions to shallow groundwater in coastal North Carolina. 
  • Evidence for a common mechanism of action for antitumor and antibacterial agents that inhibit type II DNA topoisomerases. 
  • Evidence for genetic drift in endosymbionts (Buchnera): analyses of protein-coding genes. 
  • Evolutionary design on a budget: robustness and optimality of bacteriophage T7. 
  • Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria. 
  • Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV. 
  • Expression and purification of recombinant proteins from Escherichia coli: Comparison of an elastin-like polypeptide fusion with an oligohistidine fusion. 
  • Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases. 
  • Expression in Escherichia coli of the thermostable DNA polymerase from Pyrococcus furiosus. 
  • Expression of a functional alpha-macroglobulin receptor binding domain in Escherichia coli. 
  • Expression of an EF-1 alpha-like rat cDNA, S1, in E. coli and production of a rabbit polyclonal antiserum to the recombinant protein. 
  • Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature. 
  • Extraction and identification by mass spectrometry of undecaprenyl diphosphate-MurNAc-pentapeptide-GlcNAc from Escherichia coli. 
  • FACS-optimized mutants of the green fluorescent protein (GFP). 
  • Fate and transport of enteric microbes from septic systems in a coastal watershed. 
  • Filamentous phage IKe mRNAs conserve form and function despite divergence in regulatory elements. 
  • FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria. 
  • FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae. 
  • Fimbriae-mediated host-pathogen cross-talk. 
  • Fitness consequences of altered feeding behavior in immune-challenged mosquitoes. 
  • Flavin interaction in NADPH-sulfite reductase. 
  • Flipping of the ribosomal A-site adenines provides a basis for tRNA selection. 
  • Flow cytometry sorting of recombinant mycobacterial species yields bacterial clones with enhanced insert expression. 
  • Fluorescence energy transfer between ligand binding sites on aspartate transcarbamylase. 
  • Fluorescence energy transfer between the thiamine diphosphate and flavine adenine dinucleotide binding sites on the pyruvate dehydrogenase multienzyme complex. 
  • Fluorescence energy transfer measurements between ligand binding sites of the pyruvate dehydrogenase multienzyme complex. 
  • Fluorescence energy transfer measurements in the pyruvate dehydrogenase multienzyme complex from Escherichia coli with chemically modified lipoic acid. 
  • Fluorescence polarization study of the alpha-ketoglutarate dehydrogenase complex from Escherichia coli. 
  • Fluorescence studies of the pyruvate dehydrogenase multienzyme complex from Escherichia coli. 
  • Fluorescent derivatives of the pyruvate dehydrogenase component of the Escherichia coli pyruvate dehydrogenase complex. 
  • Formation and resolution of DNA catenanes by DNA gyrase. 
  • Fragmentation of Escherichia coli type 1 fimbriae exposes cryptic D-mannose-binding sites. 
  • FtsZ condensates: an in vitro electron microscopy study. 
  • FtsZ filament dynamics at steady state: subunit exchange with and without nucleotide hydrolysis. 
  • FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima--quantitation, GTP hydrolysis, and assembly. 
  • FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli. 
  • Functional analysis of filamentous phage f1 mRNA processing sites. 
  • Functional analysis of lac repressor restart sites in translational initiation and reinitiation. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Functional heterogeneity of type 1 fimbriae of Escherichia coli. 
  • Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles. 
  • Functions that Protect Escherichia coli from Tightly Bound DNA-Protein Complexes Created by Mutant EcoRII Methyltransferase. 
  • Functions that protect Escherichia coli from DNA-protein crosslinks. 
  • Fungal toxins bind to the URF13 protein in maize mitochondria and Escherichia coli. 
  • Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins. 
  • Fusions of elastin-like polypeptides to pharmaceutical proteins. 
  • Gene A of X174. 1. Isolation and identification of its products. 
  • Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dioxygenases control glucosinolate biosynthesis in Arabidopsis. 
  • Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity. 
  • Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity. 
  • Generation of chemotactic factors in guinea pig serum via activation of the classical and alternate complement pathways. 
  • Generation of isogenic K54 capsule-deficient Escherichia coli strains through TnphoA-mediated gene disruption. 
  • Generic metric to quantify quorum sensing activation dynamics. 
  • Genes restoring redox balance in fermentation-deficient E. coli NZN111. 
  • Genetic analysis of the requirements for SOS induction by nalidixic acid in Escherichia coli. 
  • Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. 
  • Genetic bioaugmentation as an effective method for in situ bioremediation: functionality of catabolic plasmids following conjugal transfers. 
  • Genetic composition of the Bacillus subtilis SOS system. 
  • Genetic control of microsatellite stability. 
  • Genetic heterogeneity in MCAD deficiency: frequency of K329E allele and identification of three additional mutant alleles. 
  • Genetic network identification using convex programming. 
  • Genetic, biochemical, and structural studies of biogenesis of adhesive pili in bacteria. 
  • Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system. 
  • Genetically engineered probiotic competition. 
  • Genome organization and three kinds of heritable changes: general description and stochastic factors (a review). 
  • Genome-Wide Assessment of Outer Membrane Vesicle Production in Escherichia coli. 
  • Genome-scale analysis of anti-metabolite directed strain engineering. 
  • Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains. 
  • Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia. 
  • Glutathione reductases from a variety of sources are inhibited by physiological levels of glutathione. 
  • Glycerol-induced unraveling of the tight helical conformation of Escherichia coli type 1 fimbriae. 
  • Gnotobiotic models for study of the microbial ecology of Clostridium difficile and Escherichia coli. 
  • Groundwater and stream E. coli concentrations in coastal plain watersheds served by onsite wastewater and a municipal sewer treatment system. 
  • Group B Streptococcus and Escherichia coli infections in the intensive care nursery in the era of intrapartum antibiotic prophylaxis. 
  • Group II introns designed to insert into therapeutically relevant DNA target sites in human cells. 
  • HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency. 
  • HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelope. 
  • Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs. 
  • Heme-copper oxidases use tunneling pathways. 
  • Heterogeneities in fullerene nanoparticle aggregates affecting reactivity, bioactivity, and transport. 
  • Hfq structure, function and ligand binding. 
  • Hfq: a bacterial Sm-like protein that mediates RNA-RNA interaction. 
  • High dose intravenous immunoglobulin does not affect complement-bacteria interactions. 
  • High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli. 
  • High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors. 
  • High-frequency S-layer protein variation in Campylobacter fetus revealed by sapA mutagenesis. 
  • High-level 2H/13C/15N labeling of proteins for NMR studies. 
  • High-level expression and single-step purification of leucyl-tRNA synthetase from Escherichia coli. 
  • High-level expression of Escherichia coli NADPH-sulfite reductase: requirement for a cloned cysG plasmid to overcome limiting siroheme cofactor. 
  • High-level misincorporation of lysine for arginine at AGA codons in a fusion protein expressed in Escherichia coli. 
  • High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection. 
  • High-throughput screen for inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase by surrogate ligand competition. 
  • HipBA-promoter structures reveal the basis of heritable multidrug tolerance. 
  • Host defense against bacterial endotoxemia-contribution of the early and late components of complement to detoxification. 
  • How the EcoRI endonuclease recognizes and cleaves DNA. 
  • Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. 
  • Human secretory immunoglobulin A may contribute to biofilm formation in the gut. 
  • Hydrolysis of template and newly synthesized deoxyribonucleic acid by the 3' to 5' exonuclease activity of the T4 deoxyribonucleic acid polymerase. 
  • Hyperadhesive mutant of type 1-fimbriated Escherichia coli associated with formation of FimH organelles (fimbriosomes). 
  • Identification of a 21 amino acid peptide conferring 3-hydroxypropionic acid stress-tolerance to Escherichia coli. 
  • Identification of a chloroform-soluble membrane miniprotein in Escherichia coli and its homolog in Salmonella typhimurium. 
  • Identification of amino acids essential for calmodulin binding and activation of smooth muscle myosin light chain kinase. 
  • Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8. 
  • Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate. 
  • Identification of two ancillary subunits of Escherichia coli type 1 fimbriae by using antibodies against synthetic oligopeptides of fim gene products. 
  • Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA. 
  • Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. 
  • IgG bearing covalently bound C3b has enhanced bactericidal activity for Escherichia coli 0111. 
  • Image segmentation and dynamic lineage analysis in single-cell fluorescence microscopy. 
  • Imaging Escherichia coli using functionalized core/shell CdSe/CdS quantum dots. 
  • Immune adherence by the alternate complement pathway. 
  • Immunochemical properties of anti-DNA antibodies in the sera of patients with Escherichia coli bacteremia. 
  • Immunoglobulin-like PapD chaperone caps and uncaps interactive surfaces of nascently translocated pilus subunits. 
  • Immunoglobulin-mediated agglutination of and biofilm formation by Escherichia coli K-12 require the type 1 pilus fiber. 
  • Immunostimulatory properties of genomic DNA from different bacterial species. 
  • Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display. 
  • Importance of the tmRNA system for cell survival when transcription is blocked by DNA-protein cross-links. 
  • Important cellular targets for antimicrobial photodynamic therapy. 
  • Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides. 
  • Improving indel detection specificity of the Ion Torrent PGM benchtop sequencer. 
  • Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates. 
  • In Vivo and in Vitro Synthesis of Phosphatidylglycerol by an Escherichia coli Cardiolipin Synthase. 
  • In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomers. 
  • In vitro studies of complement function in sera of C4-deficient guinea pigs. 
  • In vitro synthesis of molybdopterin from precursor Z using purified converting factor. Role of protein-bound sulfur in formation of the dithiolene. 
  • In vitro synthesis of phi-X-174 single-stranded DNA. 
  • In vitro system for molybdopterin biosynthesis. 
  • In vivo characterization of Escherichia coli ftsZ mutants: effects on Z-ring structure and function. 
  • In vivo models for studying mast cell-dependent responses to bacterial infection. 
  • In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4. 
  • In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide. 
  • In-cell NMR spectroscopy in Escherichia coli. 
  • Incidence and severity of rotavirus and Escherichia coli diarrhoea in rural Bangladesh. Implications for vaccine development. 
  • Incorporation of heterologous outer membrane and periplasmic proteins into Escherichia coli outer membrane vesicles. 
  • Incorporation of secretory immunoglobulin A into biofilms can decrease their resistance to ciprofloxacin. 
  • Increasing Incidence of Extended-Spectrum β-Lactamase-Producing Escherichia coli in Community Hospitals throughout the Southeastern United States. 
  • Indole-3-acetic acid biosynthesis is deficient in Gluconacetobacter diazotrophicus strains with mutations in cytochrome c biogenesis genes. 
  • Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA. 
  • Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins. 
  • Influence of E. coli-induced prostatic inflammation on expression of androgen-responsive genes and transforming growth factor beta 1 cascade genes in rats. 
  • Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli. 
  • Influence of trimethoprim and sulfamethoxazole on the synthesis, expression, and function of type 1 fimbriae of Escherichia coli. 
  • Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli. 
  • Initiating a structural study of 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. 
  • Initiation of protein synthesis in animal mitochondria. Purification and characterization of translational initiation factor 2. 
  • Innate and adaptive immune responses in the urinary tract. 
  • Inside-out Ca(2+) signalling prompted by STIM1 conformational switch. 
  • Integration of plasmids into the bacteriophage T4 genome. 
  • Integrin beta 1 regulates phagosome maturation in macrophages through Rac expression. 
  • Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69. 
  • Interaction of Clostridium difficile and Escherichia coli with microfloras in continuous-flow cultures and gnotobiotic mice. 
  • Interaction of RNA polymerase II with structurally altered nucleosomal particles. Transcription is facilitated by loss of one H2A.H2B dimer. 
  • Interaction of a 60-kilodalton D-mannose-containing salivary glycoprotein with type 1 fimbriae of Escherichia coli. 
  • Interaction of aspartate transcarbamylase with 5-bromocytidine 5'-tri-, di-, and monophosphates. 
  • Interaction of bacteria with mast cells. 
  • Interaction of cefotaxime and desacetylcefotaxime against pathogenic bacteria. Assessment with the serum bactericidal test. 
  • Interaction of dihydrofolate reductase with methotrexate: ensemble and single-molecule kinetics. 
  • Interaction of pyridostigmine bromide and N,N-diethyl-m-toluamide alone and in combination with P-glycoprotein expressed in Escherichia coli leaky mutant. 
  • Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif. 
  • Interaction with RNA polymerase of nucleosomal cores lacking one H2A.H2B dimer. 
  • Interactions of bovine mitochondrial phenylalanyl-tRNA with ribosomes and elongation factors from mitochondria and bacteria. 
  • Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2. 
  • Internalization of FimH+ Escherichia coli by the human mast cell line (HMC-1 5C6) involves protein kinase C. 
  • Interplay between DNA replication and recombination in prokaryotes. 
  • Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates. 
  • Intracellular expression of Peptide fusions for demonstration of protein essentiality in bacteria. 
  • Intrathecal endotoxin: Intrathecal endotoxin: the role of the central nervous system in septic shock. 
  • Investigation of the early steps of molybdopterin biosynthesis in Escherichia coli through the use of in vivo labeling studies. 
  • Investigation of the role of electrostatic charge in activation of the Escherichia coli response regulator CheY. 
  • Involvement of cellular caveolae in bacterial entry into mast cells. 
  • Involvement of chlA, E, M, and N loci in Escherichia coli molybdopterin biosynthesis. 
  • Involvement of the beta clamp in methyl-directed mismatch repair in vitro. 
  • Iron enhances the bactericidal action of streptonigrin. 
  • Iron requirement in the bactericidal mechanism of streptonigrin. 
  • Isolation and analysis of recombinant DNA molecules containing yeast DNA. 
  • Isolation and characterization of a receptor for type 1 fimbriae of Escherichia coli from guinea pig erythrocytes. 
  • Isolation and characterization of lambda transducing bacteriophages for the su1+ (supD minus) amber suppressor of Escherichia coli. 
  • Isolation and characterization of the replicon of a Thiobacillus intermedius plasmid. 
  • Isolation of SOS constitutive mutants of Escherichia coli. 
  • Isolation of the structural gene for calmodulin. 
  • Isomeric N-alkylpyridylporphyrins and their Zn(II) complexes: inactive as SOD mimics but powerful photosensitizers. 
  • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. 
  • Kinetic analysis of chemotactic factor generation in human serum via activation of the classical and alternate complement pathways. 
  • Kinetic analysis of zinc ligand mutants of mammalian protein farnesyltransferase. 
  • Kinetic studies of tryptophan synthetase. Interaction of L-serine, indole, and tryptophan with the native enzyme. 
  • Kinetic studies of tryptophan synthetase. Interaction of substrates with the B subunit. 
  • Kinetics of bisulfite-induced cytosine deamination in single-stranded DNA. 
  • L-selectin (CD62L) blockade does not impair peritoneal neutrophil emigration or subcutaneous host defense to bacteria in rabbits. 
  • Laboratory investigation of diarrhea in travelers to Mexico: evaluation of methods for detecting enterotoxigenic Echerichia coli. 
  • Lambda transducing phages for the nalA gene of Escherichia coli and conditional lethal nalA mutations. 
  • Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. 
  • Left-handed DNA helices, supercoiling, and the B-Z junction. 
  • Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution. 
  • Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy. 
  • Lipopolysaccharide 3-deoxy-D-manno-octulosonic acid (Kdo) core determines bacterial association of secreted toxins. 
  • Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis. 
  • Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection. 
  • Long-term growth data of Escherichia coli at a single-cell level. 
  • Long-term monitoring of bacteria undergoing programmed population control in a microchemostat. 
  • Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene. 
  • Manganese porphyrins and related compounds as mimics of superoxide dismutase. 
  • Manganese superoxide dismutases from Escherichia coli and from yeast mitochondria: preliminary x-ray crystallographic studies. 
  • Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple. 
  • Manipulation of ligand binding affinity by exploitation of conformational coupling. 
  • Mast cell degranulation induced by type 1 fimbriated Escherichia coli in mice. 
  • Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-alpha. 
  • Mast cells as modulators of host defense in the lung. 
  • Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues. 
  • Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. 
  • Mechanism of action of the pyruvate dehydrogenase multienzyme complex from Escherichia coli. 
  • Mechanism of autophosphorylation of Escherichia coli nitrogen regulator II (NRII or NtrB): trans-phosphorylation between subunits. 
  • Mechanism of bacterial resistance to complement-mediated killing: inserted C5b-9 correlates with killing for Escherichia coli O111B4 varying in O-antigen capsule and O-polysaccharide coverage of lipid A core oligosaccharide. 
  • Mechanism of inhibition of human nonpancreatic secreted phospholipase A2 by the anti-inflammatory agent BMS-181162. 
  • Mechanism of the Class I KDPG aldolase. 
  • Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex. 
  • Mechanisms and biological effects of mismatch repair. 
  • Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). 
  • Mechanisms in eukaryotic mismatch repair. 
  • Mechanisms of DNA-mismatch correction. 
  • Mechanistic Investigation of cPMP Synthase in Molybdenum Cofactor Biosynthesis Using an Uncleavable Substrate Analogue. 
  • Mechanistic and mutational studies of Escherichia coli molybdopterin synthase clarify the final step of molybdopterin biosynthesis. 
  • Mechanistic studies of human molybdopterin synthase reaction and characterization of mutants identified in group B patients of molybdenum cofactor deficiency. 
  • Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase. 
  • Messenger RNA conformation and ribosome selection of translational reinitiation sites in the lac repressor mRNA. 
  • Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. 
  • Metabolite gene regulation of the L-arabinose operon in Escherichia coli with indoleacetic acid and other indole derivatives. 
  • Metabolite gene regulation: imidazole and imidazole derivatives which circumvent cyclic adenosine 3',5'-monophosphate in induction of the Escherichia coli L-arabinose operon. 
  • Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins. 
  • Methyl-directed repair of DNA base-pair mismatches in vitro. 1983. 
  • Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. 
  • Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides. 
  • Minimum inhibitory and bactericidal concentrations of 44 antimicrobial agents against three standard control strains in broth with and without human serum. 
  • Mismatch repair and genetic stability in human cells. 
  • Mismatch repair in replication fidelity, genetic recombination, and cancer biology. 
  • Mismatch repair, genetic stability, and cancer. 
  • Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein. 
  • Mispair specificity of methyl-directed DNA mismatch correction in vitro. 
  • Mitogenic stimulation of human B lymphocytes by the mannose-specific adhesin on Escherichia coli type 1 fimbriae. 
  • Modeling the physics of FtsZ assembly and force generation. 
  • Modification of cysteine 111 in human Cu,Zn-superoxide dismutase. 
  • Modulation of MutS ATP hydrolysis by DNA cofactors. 
  • Modulation of bacterial outer membrane vesicle production by envelope structure and content. 
  • Modulation of cell death by Bcl-XL through caspase interaction. 
  • Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA. 
  • Modulation of the binding of signal peptides to lipid bilayers by dipoles near the hydrocarbon-water interface. 
  • Modulation of the tumoricidal function of activated macrophages by bacterial endotoxin and mammalian macrophage activation factor (s). 
  • Molecular basis for paradoxical carriers of adenosine deaminase (ADA) deficiency that show extremely low levels of ADA activity in peripheral blood cells without immunodeficiency. 
  • Molecular characterization of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. Differences from spontaneous anti-DNA in the content and location of VH CDR3 arginines. 
  • Molecular cloning of rat liver sulfite oxidase. Expression of a eukaryotic Mo-pterin-containing enzyme in Escherichia coli. 
  • Molecular cloning of the gene sequences of a major apoprotein in avian very low density lipoproteins. 
  • Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins. 
  • Molecular definition of a novel inositol polyphosphate metabolic pathway initiated by inositol 1,4,5-trisphosphate 3-kinase activity in Saccharomyces cerevisiae. 
  • Molecular determinants of nuclear protein phosphatase-1 regulation by NIPP-1. 
  • Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check. 
  • Molecular properties of anti-DNA induced in preautoimmune NZB/W mice by immunization with bacterial DNA. 
  • Molybdenum cofactor biosynthesis in Escherichia coli mod and mog mutants. 
  • Molybdenum cofactor biosynthesis in Escherichia coli. Requirement of the chlB gene product for the formation of molybdopterin guanine dinucleotide. 
  • Molybdopterin biosynthesis in man. Properties of the converting factor in liver tissue from a molybdenum cofactor deficient patient. 
  • Mucosal and systemic anti-HIV responses in rhesus macaques following combinations of intranasal and parenteral immunizations. 
  • Multimeric C9 within C5b-9 is required for inner membrane damage to Escherichia coli J5 during complement killing. 
  • Multimeric complement component C9 is necessary for killing of Escherichia coli J5 by terminal attack complex C5b-9. 
  • Multiple and specific initiation of T4 DNA replication. 
  • Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor. 
  • Murine polypyrimidine tract binding protein. Purification, cloning, and mapping of the RNA binding domain. 
  • MutS mediates heteroduplex loop formation by a translocation mechanism. 
  • Mutagenesis by AID, a molecule critical to immunoglobulin hypermutation, is not caused by an alteration of the precursor nucleotide pool. 
  • Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates. 
  • Mutants of the EcoRI endonuclease with promiscuous substrate specificity implicate residues involved in substrate recognition. 
  • Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis. 
  • Mutation detection with MutH, MutL, and MutS mismatch repair proteins. 
  • Mutational analysis of the function of Met137 and Ile197, two amino acids implicated in sequence-specific DNA recognition by the EcoRI endonuclease. 
  • Mutations causing hemophilia B: direct estimate of the underlying rates of spontaneous germ-line transitions, transversions, and deletions in a human gene. 
  • Mutations in the active site of Escherichia coli phosphofructokinase. 
  • Mutations in the maize mitochondrial T-urf13 gene eliminate sensitivity to a fungal pathotoxin. 
  • Mutations that Separate the Functions of the Proofreading Subunit of the Escherichia coli Replicase. 
  • Myosin light chain kinase structure function analysis using bacterial expression. 
  • Mössbauer spectroscopic studies of Escherichia coli sulfite reductase. Evidence for coupling between the siroheme and Fe4S4 cluster prosthetic groups. 
  • N,N'-dicyclohexylcarbodiimide cross-linking suggests a central core of helices II in oligomers of URF13, the pore-forming T-toxin receptor of cms-T maize mitochondria. 
  • NF-kappaB factors are essential, but not the switch, for pathogen-related induction of the bovine beta-defensin 5-encoding gene in mammary epithelial cells. 
  • NMR studies of structure, hydrogen exchange, and main-chain dynamics in a disrupted-core mutant of thioredoxin. 
  • Negative-stain electron microscopy of inside-out FtsZ rings reconstituted on artificial membrane tubules show ribbons of protofilaments. 
  • Neonatal Escherichia coli Bloodstream Infections: Clinical Outcomes and Impact of Initial Antibiotic Therapy. 
  • Network motifs are enriched with transcription factors whose transcripts have short half-lives. 
  • Neutrophil activation by nascent FimH subunits of type 1 fimbriae purified from the periplasm of Escherichia coli. 
  • Neutrophil margination, sequestration, and emigration in the lungs of L-selectin-deficient mice. 
  • New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme. 
  • New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins. 
  • Nickel inhibits binding of alpha2-macroglobulin-methylamine to the low-density lipoprotein receptor-related protein/alpha2-macroglobulin receptor but not the alpha2-macroglobulin signaling receptor. 
  • Nitric oxide regulates endocytosis by S-nitrosylation of dynamin. 
  • Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice. 
  • Nitrosative stress: activation of the transcription factor OxyR. 
  • Nitrosative stress: metabolic pathway involving the flavohemoglobin. 
  • NlpI-mediated modulation of outer membrane vesicle production through peptidoglycan dynamics in Escherichia coli. 
  • Nomenclature relating to restriction of modified DNA in Escherichia coli. 
  • Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli. 
  • Norfloxacin-induced DNA gyrase cleavage complexes block Escherichia coli replication forks, causing double-stranded breaks in vivo. 
  • Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. 
  • Nuclease activity in a fragment of bacteriophage T4 deoxyribonucleic acid polymerase induced by the amber mutant am B22. 
  • Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1. 
  • Nucleotide pool in pho regulon mutants and alkaline phosphatase synthesis in Escherichia coli. 
  • Nucleotide sequence and high-level expression of the major Escherichia coli phosphofructokinase. 
  • Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. 
  • On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. 
  • Optimality and robustness in quorum sensing (QS)-mediated regulation of a costly public good enzyme. 
  • Optimization of expression of human sulfite oxidase and its molybdenum domain. 
  • Optimizing Zn porphyrin-based photosensitizers for efficient antibacterial photodynamic therapy. 
  • Order out of disorder: working cycle of an intrinsically unfolded chaperone. 
  • Orientation of LamB signal peptides in bilayers: influence of lipid probes on peptide binding and interpretation of fluorescence quenching data. 
  • Oscillations by minimal bacterial suicide circuits reveal hidden facets of host-circuit physiology. 
  • Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein. 
  • Outer membrane vesicle production by Escherichia coli is independent of membrane instability. 
  • Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels. 
  • Overproduction and purification of glutaryl 7-amino cephalosporanic acid acylase. 
  • OxyR: a molecular code for redox-related signaling. 
  • P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips. 
  • Parallel mapping of genotypes to phenotypes contributing to overall biological fitness. 
  • Pathogenesis of escherichia coli gastroenteritis in man--another mechanism. 
  • Pathogenic Escherichia coli in children with and without chronic diarrhea in Tanzania. 
  • Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation. 
  • Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli. 
  • Pediatric-specific antimicrobial susceptibility data and empiric antibiotic selection. 
  • Peeing pentraxins. 
  • Persistence and reversal of plasmid-mediated antibiotic resistance. 
  • Phage Trojan horses: a conditional expression system for lethal genes. 
  • Phage fl mRNA processing in Escherichia coli: search for the upstream products of endonuclease cleavage, requirement for the product of the altered mRNA stability (ams) locus. 
  • Phenylalanine 30 plays an important role in receptor binding of verotoxin-1. 
  • Phosphoproteins involved in bacterial signal transduction. 
  • Phosphorylation of O6-alkylguanine-DNA alkyltransferase: experience with a GST-fusion protein and a new pull-down assay. 
  • Photoselected electron transfer pathways in DNA photolyase. 
  • Phytochrome regulation and differential expression of gibberellin 3beta-hydroxylase genes in germinating Arabidopsis seeds. 
  • Plasmid models for bacteriophage T4 DNA replication: requirements for fork proteins. 
  • Plasmids for expression of chimeric and truncated kinesin proteins. 
  • Poly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sites. 
  • Polymerization of Ftsz, a bacterial homolog of tubulin. is assembly cooperative? 
  • Polyspecific binding of Escherichia coli beta-galactosidase by murine antibodies to DNA. 
  • Possible production of immunosuppression in the host by exposure to microorganisms: observations in germfree rats. 
  • Postinduction dexamethasone and individualized dosing of Escherichia Coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: results from a randomized study--Dana-Farber Cancer Institute ALL Consortium Protocol 00-01. 
  • Predicting transition temperatures of elastin-like polypeptide fusion proteins. 
  • Preliminary X-ray diffraction studies of acyl carrier protein from Escherichia coli. 
  • Preliminary X-ray diffraction studies on the hemoprotein subunit of Escherichia coli sulfite reductase. 
  • Primary structure and domain organization of human alpha and beta adducin. 
  • Probing for Binding Regions of the FtsZ Protein Surface through Site-Directed Insertions: Discovery of Fully Functional FtsZ-Fluorescent Proteins. 
  • Probing the DNA sequence specificity of Escherichia coli RECA protein. 
  • Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of the Escherichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products. 
  • Probing the domain structure of FtsZ by random truncation and insertion of GFP. 
  • Processing of intermediates in multienzyme complexes. 
  • Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate. 
  • Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a phase I/II clinical trial. 
  • Prognostic significance of early response to a single dose of asparaginase in childhood acute lymphoblastic leukemia. 
  • Programmable assembly of pressure sensors using pattern-forming bacteria. 
  • Programmed Allee effect in bacteria causes a tradeoff between population spread and survival. 
  • Programmed population control by cell-cell communication and regulated killing. 
  • Programming stress-induced altruistic death in engineered bacteria. 
  • Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy. 
  • Proliferation behavior of E. coli in a three-dimensional in vitro tumor model. 
  • Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium. 
  • Protection against Escherichia coli-induced urinary tract infections with hybridoma antibodies directed against type 1 fimbriae or complementary D-mannose receptors. 
  • Protein biosynthesis on chick oviduct polyribosomes. I. Changes during estrogen-mediated tissue differentiation. 
  • Protein fabrication automation. 
  • Protein purification by fusion with an environmentally responsive elastin-like polypeptide: effect of polypeptide length on the purification of thioredoxin. 
  • Proton NMR of Escherichia coli sulfite reductase: studies of the heme protein subunit with added ligands. 
  • Proton NMR of Escherichia coli sulfite reductase: the unligated hemeprotein subunit. 
  • Protonation state of Glu142 differs in the green- and blue-absorbing variants of proteorhodopsin. 
  • Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. 
  • Purification and assembly of FtsZ. 
  • Purification and characterization of the Cu,Zn SOD from Escherichia coli. 
  • Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli. 
  • Purification and mutagenesis of LpxL, the lauroyltransferase of Escherichia coli lipid A biosynthesis. 
  • Purification of an elastin-like fusion protein by microfiltration. 
  • Purification of recombinant proteins from Escherichia coli at low expression levels by inverse transition cycling. 
  • Purification of the HhaII restriction endonuclease from an overproducer Escherichia coli clone. 
  • Purification of the bacteriophage T4 type II DNA topoisomerase. 
  • Purified MotA protein binds the -30 region of a bacteriophage T4 middle-mode promoter and activates transcription in vitro. 
  • Purified lac permease and cytochrome o oxidase are functional as monomers. 
  • Quality control limits for ampicillin, carbenicillin, mezlocillin, and piperacillin disk diffusion susceptibility tests: a collaborative study. 
  • Quantitative and selective fluorophore labeling of phosphoserine on peptides and proteins: characterization at the attomole level by capillary electrophoresis and laser-induced fluorescence. 
  • Quantitative immunoassay of anti-La antibodies using purified recombinant La antigen. 
  • Quantitative protein stability measurement in vivo. 
  • RNA binding specificity of a Drosophila snRNP protein that shares sequence homology with mammalian U1-A and U2-B" proteins. 
  • RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins. 
  • Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties. 
  • Rapid 16S ribosomal DNA sequencing from a single colony without DNA extraction or purification. 
  • Rapid Antimicrobial Susceptibility Testing Using Forward Laser Light Scatter Technology. 
  • Rapid Detection of Urinary Tract Infections via Bacterial Nuclease Activity. 
  • Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II. 
  • Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching. 
  • Rapid determination of protein folds using residual dipolar couplings. 
  • Rapid dissection of a complex phenotype through genomic-scale mapping of fitness altering genes. 
  • Rapid kinetic-based screening of human Fab fragments. 
  • Rapid separation and characterization of protein and peptide mixtures using 1.5 microns diameter non-porous silica in packed capillary liquid chromatography/mass spectrometry. 
  • Rapid translocation of bacteria in small bowel transplantation. 
  • Re-design of Rhodobacter sphaeroides dimethyl sulfoxide reductase. Enhancement of adenosine N1-oxide reductase activity. 
  • Recognition and cleavage signals for mRNA processing lie within local domains of the phage f1 RNA precursors. 
  • Recognition of single-stranded DNA by the bacteriophage T4-induced type II topoisomerase. 
  • Recognition of β-strand motifs by RseB is required for σ(E) activity in Escherichia coli. 
  • Recombinant Rhodobacter capsulatus xanthine dehydrogenase, a useful model system for the characterization of protein variants leading to xanthinuria I in humans. 
  • Recombination hotspots in bacteriophage T4 are dependent on replication origins. 
  • Recombination-dependent DNA replication stimulated by double-strand breaks in bacteriophage T4. 
  • Reconstitution of contractile FtsZ rings in liposomes. 
  • Reconstitution of protein translocation from detergent-solubilized Escherichia coli inverted vesicles: PrlA protein-deficient vesicles efficiently translocate precursor proteins. 
  • Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes. 
  • Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution. 
  • Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. IV. The Escherichia coli hemoflavoprotein: subunit structure and dissociation into hemoprotein and flavoprotein components. 
  • Reducing Environmental Toxicity of Silver Nanoparticles through Shape Control. 
  • Regression supports two mechanisms of fork processing in phage T4. 
  • Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle. 
  • Regulation of enzyme activity. The activity of enzymes can be controlled by a multiplicity of conformational equilibria. 
  • Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis. 
  • Relation between the redox state of iron-based nanoparticles and their cytotoxicity toward Escherichia coli. 
  • Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli. 
  • Relaxation spectra of aspartate transcarbamylase. I. Interaction of 5-bromocytidine triphosphate with native enzyme and regulatory subunit. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the catalytic subunit with carbamyl phosphate, succinate, and L-malate. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with an adenosine 5'-triphosphate analog. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with aspartate analogs. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with carbamyl phosphate. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with cytidine 5'-triphosphate. 
  • Release of outer membrane vesicles by Gram-negative bacteria is a novel envelope stress response. 
  • Remodelling of the Vibrio cholerae membrane by incorporation of exogenous fatty acids from host and aquatic environments. 
  • Removal of polymerase-produced mutant sequences from PCR products. 
  • Repair of the Escherichia coli chromosome after in vivo scission by the EcoRI endonuclease. 
  • Replication of the Escherichia coli chromosome in RNase HI-deficient cells: multiple initiation regions and fork dynamics. 
  • Resistance of Yersinia pestis to complement-dependent killing is mediated by the Ail outer membrane protein. 
  • Resonance Raman studies of Escherichia coli sulfite reductase hemoprotein. 1. Siroheme vibrational modes. 
  • Resonance Raman studies of Escherichia coli sulfite reductase hemoprotein. 2. Fe4S4 cluster vibrational modes. 
  • Resonance Raman studies of Escherichia coli sulfite reductase hemoprotein. 3. Bound ligand vibrational modes. 
  • Reversal of P-glycoprotein expressed in Escherichia coli leaky mutant by ascorbic acid. 
  • Revisiting the steady state kinetic mechanism of glutamine-dependent asparagine synthetase from Escherichia coli. 
  • Rhythmic bacterial susceptibility to antibiotics at a large hospital. 
  • Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing. 
  • Ribozyme-mediated revision of RNA and DNA. 
  • Robust, linear correlations between growth rates and β-lactam-mediated lysis rates. 
  • Role of Escherichia coli DNA polymerase I in conferring viability upon the dnaN159 mutant strain. 
  • Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. 
  • Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomes. 
  • Role of bacterial lectins in urinary tract infections. Molecular mechanisms for diversification of bacterial surface lectins. 
  • Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. 
  • Role of conserved residues within the carboxy phosphate domain of carbamoyl phosphate synthetase. 
  • Role of enzyme-bound 5,10-methenyltetrahydropteroylpolyglutamate in catalysis by Escherichia coli DNA photolyase. 
  • Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis. 
  • Role of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance. 
  • Roles of polyadenylation and nucleolytic cleavage in the filamentous phage mRNA processing and decay pathways in Escherichia coli. 
  • S-nitrosylation in the regulation of gene transcription. 
  • S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4. 
  • SCALEs: multiscale analysis of library enrichment. 
  • SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. 
  • SOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itself. 
  • SOS induction as an in vivo assay of enzyme-DNA interactions. 
  • Safety of incremental inhaled lipopolysaccharide challenge in humans. 
  • Salmonella typhimurium SA host specificity system is based on deoxyribonucleic acid-adenine methylation. 
  • Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform. 
  • Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization. 
  • Screening for nitric oxide-dependent protein-protein interactions. 
  • Seasonal peaks in Escherichia coli infections: possible explanations and implications. 
  • Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili. 
  • Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix. 
  • Serum dilution test for bactericidal activity. I. Selection of a physiologic diluent. 
  • Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition. 
  • Significance of complement to the mechanism of action of endotoxin. 
  • Single-molecule and transient kinetics investigation of the interaction of dihydrofolate reductase with NADPH and dihydrofolate. 
  • Site-directed mutagenesis in the effector site of Escherichia coli phosphofructokinase. 
  • Site-directed mutagenesis of recombinant sulfite oxidase: identification of cysteine 207 as a ligand of molybdenum. 
  • Site-specific incorporation of 3-nitrotyrosine as a probe of pKa perturbation of redox-active tyrosines in ribonucleotide reductase. 
  • Site-specific methylases induce the SOS DNA repair response in Escherichia coli. 
  • Site-specific mutations of FtsZ--effects on GTPase and in vitro assembly. 
  • Site-specific recognition of bacteriophage T4 DNA by T4 type II DNA topoisomerase and Escherichia coli DNA gyrase. 
  • Sliding clamp-DNA interactions are required for viability and contribute to DNA polymerase management in Escherichia coli. 
  • SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid. 
  • Solid-phase microtiter radioimmunoassay blocking test for detection of antibodies to Escherichia coli heat-labile enterotoxin. 
  • Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem. 
  • Specific 33-residue repeat(s) of erythrocyte ankyrin associate with the anion exchanger. 
  • Specificity of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. 
  • Specificity of human bactericidal antibodies against PorA P1.7,16 induced with a hexavalent meningococcal outer membrane vesicle vaccine. 
  • Stability of oxidized Escherichia coli thioredoxin and its dependence on protonation of the aspartic acid residue in the 26 position. 
  • Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling. 
  • Stimulation and inhibition of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced strand breaks and interstrand cross-linking in Col E1 plasmid deoxyribonucleic acid by polyamines and inorganic cations. 
  • Stimulation of mutations suppressing the loss of replication control by small alcohols. 
  • Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC. 
  • Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase. 
  • Structural and immunological comparison of indigenous human O6-methylguanine-DNA methyltransferase with that encoded by a cloned cDNA. 
  • Structural and mechanistic studies of the alpha-ketoglutarate dehydrogenase multienzyme complex from Escherichia coli. 
  • Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. 
  • Structural basis for the differential regulation of DNA by the methionine repressor MetJ. 
  • Structural basis of lipid binding for the membrane-embedded tetraacyldisaccharide-1-phosphate 4'-kinase LpxK. 
  • Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC. 
  • Structural characterization of a molybdopterin precursor. 
  • Structural characterization of ordered arrays of sn-glycerol-3-phosphate acyltransferase from Escherichia coli. 
  • Structural determinants for signal sequence function in the mammalian endoplasmic reticulum. 
  • Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain. 
  • Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase. 
  • Structural mechanism of ATP-induced polymerization of the partition factor ParF: implications for DNA segregation. 
  • Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors. 
  • Structural requirements for high affinity ligand binding by estrogen receptors: a comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast, and mammalian cells. 
  • Structural studies of molybdopterin synthase provide insights into its catalytic mechanism. 
  • Structure and activities of Escherichia coli DNA gyrase. 
  • Structure and stability of monomeric lambda repressor: NMR evidence for two-state folding. 
  • Structure of DNA polymerase I Klenow fragment bound to duplex DNA. 
  • Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. 
  • Structure of oxidative- and photo-phosphorylation coupling factor complexes. 
  • Structure of the LpxC deacetylase with a bound substrate-analog inhibitor. 
  • Structure of the Z Ring-associated Protein, ZapD, Bound to the C-terminal Domain of the Tubulin-like Protein, FtsZ, Suggests Mechanism of Z Ring Stabilization through FtsZ Cross-linking. 
  • Structure of the eukaryotic transcription apparatus: features of the gene for the largest subunit of Drosophila RNA polymerase II. 
  • Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy. 
  • Structure-guided reprogramming of serine recombinase DNA sequence specificity. 
  • Structures of ParB bound to DNA reveal mechanism of partition complex formation. 
  • Structures of the bacterial ribosome in classical and hybrid states of tRNA binding. 
  • Studies of the mechanism of bacterial resistance to complement-mediated killing. V. IgG and F(ab')2 mediate killing of E. coli 0111B4 by the alternative complement pathway without increasing C5b-9 deposition. 
  • Studies on DNA replication in the bacteriophage T4 in vitro system. 
  • Studies on the mechanism of bacterial resistance to complement-mediated killing. VI. IgG increases the bactericidal efficiency of C5b-9 for E. coli 0111B4 by acting at a step before C5 cleavage. 
  • Study of Cryptococcus neoformans actin gene regulation with a beta-galactosidase-actin fusion. 
  • Substitutions in bacteriophage T4 AsiA and Escherichia coli sigma(70) that suppress T4 motA activation mutations. 
  • Substrate Selectivity of Lysophospholipid Transporter LplT Involved in Membrane Phospholipid Remodeling in Escherichia coli. 
  • Substrate recognition by the EcoRI endonuclease. 
  • Subunit IV of cytochrome bc1 complex from Rhodobacter sphaeroides. Localization of regions essential for interaction with the three-subunit core complex. 
  • Subunit stoichiometry and molecular weight of the pyruvate dehydrogenase multienzyme complex from Escherichia coli. 
  • Suicide substrates for the alanine racemase of Escherichia coli B. 
  • SulA inhibits assembly of FtsZ by a simple sequestration mechanism. 
  • Sulfite reductase structure at 1.6 A: evolution and catalysis for reduction of inorganic anions. 
  • Superoxide dismutase from Streptococcus mutans. Isolation and characterization of two forms of the enzyme. 
  • Superoxidized states of Escherichia coli sulfite reductase heme protein subunit. 
  • Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic. 
  • Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection. 
  • Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold. 
  • Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist. 
  • Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement. 
  • Synthetic effect between envelope stress and lack of outer membrane vesicle production in Escherichia coli. 
  • Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma. 
  • T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. 
  • TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder. 
  • TLR4-mediated expulsion of bacteria from infected bladder epithelial cells. 
  • Temperature-inducible amber suppressor: construction of plasmids containing the Escherichia coli serU- (supD-) gene under control of the bacteriophage lambda pL promoter. 
  • Temperature-sensitive mutants of the EcoRI endonuclease. 
  • Temporal control of self-organized pattern formation without morphogen gradients in bacteria. 
  • Tetramerization and single-stranded DNA binding properties of native and mutated forms of murine mitochondrial single-stranded DNA-binding proteins. 
  • The C-terminal linker of Escherichia coli FtsZ functions as an intrinsically disordered peptide. 
  • The Drosophila claret segregation protein is a minus-end directed motor molecule. 
  • The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling. 
  • The Mechanism of HdeA Unfolding and Chaperone Activation. 
  • The PapG tip adhesin of P fimbriae protects Escherichia coli from neutrophil bactericidal activity. 
  • The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. 
  • The Tn3 beta-lactamase gene acts as a hotspot for meiotic recombination in yeast. 
  • The U1 RNA-binding site of the U1 small nuclear ribonucleoprotein (snRNP)-associated A protein suggests a similarity with U2 snRNPs. 
  • The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-kappaB activation. 
  • The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. 
  • The biological activity of a liposomal complete core lipopolysaccharide vaccine. 
  • The biosynthesis of molybdopterin in Escherichia coli. Purification and characterization of the converting factor. 
  • The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation. 
  • The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. 
  • The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin. 
  • The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis. 
  • The distinct binding specificities exhibited by enterobacterial type 1 fimbriae are determined by their fimbrial shafts. 
  • The effect of covalently immobilized rhIL-1ra-ELP fusion protein on the inflammatory profile of LPS-stimulated human monocytes. 
  • The epsilon subunit of DNA polymerase III Is involved in the nalidixic acid-induced SOS response in Escherichia coli. 
  • The family of glycogen phosphorylases: structure and function. 
  • The filamentous bacteriophage assembly proteins require the bacterial SecA protein for correct localization to the membrane. 
  • The folate cofactor of Escherichia coli DNA photolyase acts catalytically. 
  • The genetic determinant of adhesive function in type 1 fimbriae of Escherichia coli is distinct from the gene encoding the fimbrial subunit. 
  • The heme and Fe4S4 cluster in the crystallographic structure of Escherichia coli sulfite reductase. 
  • The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence. 
  • The hydrophobic core of Escherichia coli thioredoxin shows a high tolerance to nonconservative single amino acid substitutions. 
  • The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction. 
  • The importance of binding energy in catalysis of hydride transfer by UDP-galactose 4-epimerase: a 13C and 15N NMR and kinetic study. 
  • The importance of repairing stalled replication forks. 
  • The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens. 
  • The inoculum effect and band-pass bacterial response to periodic antibiotic treatment. 
  • The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics. 
  • The mast cell tumor necrosis factor alpha response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48. 
  • The mode of death of pig kidney cells infected with cowpox virus is governed by the expression of the crmA gene. 
  • The nature of immune responses to urinary tract infections. 
  • The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic. 
  • The presence and distribution of reduced folates in Escherichia coli dihydrofolate reductase mutants. 
  • The products of gene I and the overlapping in-frame gene XI are required for filamentous phage assembly. 
  • The pterin molybdenum cofactors. 
  • The rational design and construction of a cuboidal iron-sulfur protein. 
  • The relationship between the mitochondrial gene T-urf13 and fungal pathotoxin sensitivity in maize. 
  • The role of Toll-like receptor 4 in environmental airway injury in mice. 
  • The role of carbohydrate in the function of human plasminogen: comparison of the protein obtained from molecular cloning and expression in Escherichia coli and COS cells. 
  • The role of cpg sequences in the induction of anti-DNA antibodies. 
  • The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes. 
  • The role of the central nervous system in septic shock. I. Pathologic changes following intraventricular and intracisternal endotoxin in the dog. 
  • The role of the macrophage scavenger receptor in immune stimulation by bacterial DNA and synthetic oligonucleotides. 
  • The structure of a molybdopterin precursor. Characterization of a stable, oxidized derivative. 
  • The variable CT appearance of hepatic abscesses. 
  • Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes. 
  • Thermodynamic effects of reduction of the active-site disulfide of Escherichia coli thioredoxin explored by differential scanning calorimetry. 
  • Thermodynamic evaluation of binding interactions in the methionine repressor system of Escherichia coli using isothermal titration calorimetry. 
  • Thermodynamics of reactions catalyzed by PABA synthase. 
  • Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides. 
  • Time series analysis of rhythmic bacterial resistance development to antibiotics. 
  • Timing of valproic acid in acute lung injury: prevention is the best therapy? 
  • Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes. 
  • TnphoA-mediated disruption of K54 capsular polysaccharide genes in Escherichia coli confers serum sensitivity. 
  • Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide. 
  • Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide. 
  • Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli. 
  • Toxicity of expanded polyglutamine-domain proteins in Escherichia coli. 
  • Tracking the in vivo fate of recombinant polypeptides by isotopic labeling. 
  • Transcription of bacteriophage fl. The major in vivo RNAs. 
  • Transcriptional pausing in a region important for plasmid NR1 replication control. 
  • Travelers' diarrhea in Mexico. A prospective study of physicians and family members attending a congress. 
  • Travelers' diarrhea. 
  • Two oligomeric forms of plasma ficolin have differential lectin activity. 
  • Two proteins encoded at the chlA locus constitute the converting factor of Escherichia coli chlA1. 
  • Two types of mechanosensitive channels in the Escherichia coli cell envelope: solubilization and functional reconstitution. 
  • Two-dimensional gel analysis of rolling circle replication in the presence and absence of bacteriophage T4 primase. 
  • Two-dimensional protein crystallization via metal-ion coordination by naturally occurring surface histidines. 
  • Type 1 fimbrial shafts of Escherichia coli and Klebsiella pneumoniae influence sugar-binding specificities of their FimH adhesins. 
  • Type 1 fimbriated Escherichia coli-mast cell interactions in cystitis. 
  • Type I elements mediate replication fork pausing at conserved upstream sites in the Tetrahymena thermophila ribosomal DNA minichromosome. 
  • URF13, a maize mitochondrial pore-forming protein, is oligomeric and has a mixed orientation in Escherichia coli plasma membranes. 
  • UVA generates pyrimidine dimers in DNA directly. 
  • Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex. 
  • Ultra-high expression of a thermally responsive recombinant fusion protein in E. coli. 
  • Uncoupling of nucleotide hydrolysis and polymerization in the ParA protein superfamily disrupts DNA segregation dynamics. 
  • Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. 
  • Unsaturated fatty acid requirement in Escherichia coli: mechanism of palmitate-induced inhibition of growth of strain WN1. 
  • Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. 
  • Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC. 
  • Urinary catheter capable of repeated on-demand removal of infectious biofilms via active deformation. 
  • Urinary tract infection due to laboratory-acquired Escherichia coli: relation to virulence. 
  • Use of antisera for identification of enterotoxigenic Escherichia coli. 
  • Use of colony pools for diagnosis of enterotoxigenic Escherichia coli diarrhea. 
  • Use of monoclonal antibodies to probe subunit- and polymer-specific epitopes of 987P fimbriae of Escherichia coli. 
  • Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol. 
  • UvsW protein regulates bacteriophage T4 origin-dependent replication by unwinding R-loops. 
  • VA/Q abnormalities during gram negative sepsis. 
  • Valproic acid mitigates the inflammatory response and prevents acute respiratory distress syndrome in a murine model of Escherichia coli pneumonia at the expense of bacterial clearance. 
  • Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury. 
  • Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. 
  • Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ. 
  • Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States. 
  • lac repressor blocks in vivo transcription of lac control region DNA. 
  • mRNA processing in Escherichia coli: an activity encoded by the host processes bacteriophage f1 mRNAs. 
  • trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1. 
• 

  Keywords of People

  • Aballay, Alejandro, Adjunct Professor in the Department of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology
  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • Carbrey, Jennifer Mehlman, Assistant Research Professor of Cell Biology, Cell Biology
  • Chen, Jun, Associate Professor of Medicine, Duke Cancer Institute
  • Cohen-Wolkowiez, Michael, Professor of Pediatrics, Pediatrics, Infectious Diseases
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Gottlin, Elizabeth B., Assistant Professor in Radiology, Radiology
  • Guan, Ziqiang, Research Professor in Biochemistry, Biochemistry
  • Gunn, Michael Dee, Professor of Medicine, Immunology
  • Kuehn, Margarethe Joanna, Associate Professor of Biochemistry, Molecular Genetics and Microbiology
  • Liton, Paloma Borrajo, Associate Professor in Ophthalmology, Pathology
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Zhang, Zhiquan, Assistant Professor in Anesthesiology, Anesthesiology