Escherichia coli Infections

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  Subject Areas on Research

  • A 9-Year retrospective review of antibiotic cycling in a surgical intensive care unit. 
  • A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion. 
  • A comparative study of the mannose-resistant and mannose-sensitive haemagglutinins of Escherichia coli isolated from urinary tract infections. 
  • A multicenter comparative trial of three-day norfloxacin vs ten-day sulfamethoxazole and trimethoprim for the treatment of uncomplicated urinary tract infections. 
  • A multicenter, double-blind, trimethoprim-sulfamethoxazole controlled study of enoxacin in the treatment of patients with complicated urinary tract infections. 
  • A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells. 
  • A prospective study of Escherichia coli bloodstream infection among adolescents and adults in northern Tanzania. 
  • A sublingual nanofiber vaccine to prevent urinary tract infections. 
  • A two-year study of bacterial, viral, and parasitic agents associated with diarrhea in rural Bangladesh. 
  • Altered mitochondrial redox responses in gram negative septic shock in primates. 
  • An outbreak of Escherichia coli O157 infection following exposure to a contaminated building. 
  • An outbreak of Escherichia coli O157:H7 infections among visitors to a dairy farm. 
  • Analysis of the real EADGENE data set: comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (open access publication). 
  • Analysis of the real EADGENE data set: multivariate approaches and post analysis (open access publication). 
  • Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis. 
  • Antibiotic Susceptibility of Escherichia coli Among Infants Admitted to Neonatal Intensive Care Units Across the US From 2009 to 2017. 
  • Antibody to E- and L-selectin does not prevent lung injury or mortality in septic baboons. 
  • Application of a microcomputer-based system in the analysis of infection data at the emergency units of a large hospital. 
  • Assessment of the immune capacity of mammary epithelial cells: comparison with mammary tissue after challenge with Escherichia coli. 
  • Autochthonous ST405 NDM-5 producing Escherichia coli causing fatal sepsis in Northern Italy. 
  • Bacterial infection early in life protects against stressor-induced depressive-like symptoms in adult rats. 
  • Bacterial meningitis in infants. 
  • Blockade of tissue factor-factor X binding attenuates sepsis-induced respiratory and renal failure. 
  • Blockade of tissue factor: treatment for organ injury in established sepsis. 
  • Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. 
  • Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types. 
  • Coagulation blockade prevents sepsis-induced respiratory and renal failure in baboons. 
  • Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium. 
  • Comparison of cinoxacin and nalidixic acid in patients with cystitis. 
  • Contamination of weaning foods and transmission of enterotoxigenic Escherichia coli diarrhoea in children in rural Bangladesh. 
  • Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells. 
  • Depletion of polymorphonuclear leukocytes has no effect on preterm delivery in a mouse model of Escherichia coli-induced labor. 
  • Detection of Escherichia coli enterotoxins in stools. 
  • Diarrhea, demography and cell signaling: lessons from microbial toxins. 
  • Diarrhoea associated with heat-stable enterotoxin-producing strains of Escherichia coli. 
  • Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. 
  • Disease due to enterotoxigenic Escherichia coli in Bangladeshi adults: clinical aspects and a controlled trial of tetracycline. 
  • Doxycycline and the traveller. 
  • Early onset neonatal sepsis: the burden of group B Streptococcal and E. coli disease continues. 
  • Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies. 
  • Early-life infection is a vulnerability factor for aging-related glial alterations and cognitive decline. 
  • Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. 
  • Editorial: Toxigenic turista. 
  • Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation. 
  • Effect of glutamine-supplemented intravenous nutrition on survival after Escherichia coli-induced peritonitis. 
  • Effects of Shigella-, Campylobacter- and ETEC-associated diarrhea on childhood growth. 
  • Effects of enteral feeding products on survival from Escherichia coli peritonitis. 
  • Effects of pneumoperitoneum on hemodynamic and systemic immunologic responses to peritonitis in pigs. 
  • Eicosanoids and the hemodynamic course of live Escherichia coli-induced sepsis in baboons. 
  • Emergence of extended-spectrum beta-lactamase-producing Escherichia coli in community hospitals throughout North Carolina: a harbinger of a wider problem in the United States? 
  • Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain. 
  • Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder. 
  • Enteroaggregative Escherichia coli Subclinical Infection and Coinfections and Impaired Child Growth in the MAL-ED Cohort Study. 
  • Enteroinvasive Escherichia coli: a cause of bacteremia in patients with AIDS. 
  • Enterotoxigenic Escherichia coli and Reovirus-like agent in rural Bangladesh. 
  • Enterotoxigenic Escherichia coli diarrhoea: acquired immunity and transmission in an endemic area. 
  • Escherichia coli global gene expression in urine from women with urinary tract infection. 
  • Escherichia coli, but not Staphylococcus aureus triggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow. 
  • Evolution of STEC virulence: Insights from the antipredator activities of Shiga toxin producing E. coli. 
  • Fimbriae-mediated host-pathogen cross-talk. 
  • From Rwanda to Wisconsin: the global relevance of diarrhoeal diseases. 
  • Genetic, biochemical, and structural studies of biogenesis of adhesive pili in bacteria. 
  • Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains. 
  • Group B Streptococcus and Escherichia coli infections in the intensive care nursery in the era of intrapartum antibiotic prophylaxis. 
  • Gut microbial succession follows acute secretory diarrhea in humans. 
  • Histone Deacetylase 7 Inhibition in a Murine Model of Gram-Negative Pneumonia-Induced Acute Lung Injury. 
  • Immunochemical properties of anti-DNA antibodies in the sera of patients with Escherichia coli bacteremia. 
  • Incidence and severity of rotavirus and Escherichia coli diarrhoea in rural Bangladesh. Implications for vaccine development. 
  • Increasing Incidence of Extended-Spectrum β-Lactamase-Producing Escherichia coli in Community Hospitals throughout the Southeastern United States. 
  • Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli. 
  • Innate and adaptive immune responses in the urinary tract. 
  • Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells. 
  • Kidney α-intercalated cells and lipocalin 2: defending the urinary tract. 
  • L-selectin (CD62L) blockade does not impair peritoneal neutrophil emigration or subcutaneous host defense to bacteria in rabbits. 
  • LPS elicits a much larger and broader inflammatory response than Escherichia coli infection within the hippocampus of neonatal rats. 
  • Lactobacillus crispatus Limits Bladder Uropathogenic E. coli Infection by Triggering a Host Type I Interferon Response. 
  • Local induction of bladder Th1 responses to combat urinary tract infections. 
  • Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues. 
  • Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016. 
  • NF-kappaB factors are essential, but not the switch, for pathogen-related induction of the bovine beta-defensin 5-encoding gene in mammary epithelial cells. 
  • Neonatal E. coli infection causes neuro-behavioral deficits associated with hypomyelination and neuronal sequestration of iron. 
  • Neonatal Escherichia coli Bloodstream Infections: Clinical Outcomes and Impact of Initial Antibiotic Therapy. 
  • Neonatal Escherichia coli infection alters glial, cytokine, and neuronal gene expression in response to acute amphetamine in adolescent rats. 
  • Neonatal bacterial infection alters fever to live and simulated infections in adulthood. 
  • Neonatal infection induces memory impairments following an immune challenge in adulthood. 
  • Neonatal infection modulates behavioral flexibility and hippocampal activation on a Morris Water Maze task. 
  • Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. 
  • Nitric oxide synthase-2 induction optimizes cardiac mitochondrial biogenesis after endotoxemia. 
  • Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice. 
  • Nutritional status, body size and severity of diarrhoea associated with rotavirus or enterotoxigenic Escherichia coli. 
  • Outbreaks of Escherichia coli O157 infections at multiple county agricultural fairs: a hazard of mixing cattle, concession stands and children. 
  • PROLONGED RUPTURE OF FETAL MEMBRANES. 
  • Part III. Analysis of data gaps pertaining to enterotoxigenic Escherichia coli infections in low and medium human development index countries, 1984-2005. 
  • Partial liquid ventilation reduces pulmonary neutrophil accumulation in an experimental model of systemic endotoxemia and acute lung injury. 
  • Pathogenesis of escherichia coli gastroenteritis in man--another mechanism. 
  • Pediatric-specific antimicrobial susceptibility data and empiric antibiotic selection. 
  • Peeing pentraxins. 
  • Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements. 
  • Postconception age and other risk factors associated with mortality following Gram-negative rod bacteremia. 
  • Predominant bacteria and patterns of antibiotic susceptibility in urinary tract infection in children with spina bifida. 
  • Prevention of traveler's diarrhea. 
  • Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy. 
  • Protection against Escherichia coli-induced urinary tract infections with hybridoma antibodies directed against type 1 fimbriae or complementary D-mannose receptors. 
  • Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis. 
  • Seasonal peaks in Escherichia coli infections: possible explanations and implications. 
  • Serologic differentiation between antitoxin responses to infection with Vibrio cholerae and enterotoxin-producing Escherichia coli. 
  • Simultaneous thigh muscle metastasis from lung cancer and Escherichia coli gas producing myonecrosis. 
  • Solid-phase microtiter radioimmunoassay blocking test for detection of antibodies to Escherichia coli heat-labile enterotoxin. 
  • Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection. 
  • The PapG tip adhesin of P fimbriae protects Escherichia coli from neutrophil bactericidal activity. 
  • The immune system and developmental programming of brain and behavior. 
  • Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans. 
  • Urinary tract infection due to laboratory-acquired Escherichia coli: relation to virulence. 
  • Uropathogenic Escherichia coli subverts mitochondrial metabolism to enable intracellular bacterial pathogenesis in urinary tract infection. 
  • Use of Placental/Umbilical Blood Sampling for Neonatal Admission Blood Cultures: Benefits, Challenges, and Strategies for Implementation. 
  • Use of colony pools for diagnosis of enterotoxigenic Escherichia coli diarrhea. 
  • Xanthogranulomatous pyelonephritis in renal transplant recipient. 
  • α-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification. 
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  Keywords of People

  • Cohen-Wolkowiez, Michael, Kiser-Arena Distinguished Professor, Pediatrics, Infectious Diseases
  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology