Ethacrynic Acid
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Subject Areas on Research
- Cellular pharmacokinetic and pharmacodynamic analyses of ethacrynic acid: Implications in topical drug delivery in the eye.
- Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus.
- Comparative metabolism and excretion of benzo(a)pyrene in 2 species of ictalurid catfish.
- Controlled release of ethacrynic acid from poly(lactide-co-glycolide) films for glaucoma treatment.
- Dexamethasone inhibits trabecular cell retraction.
- Diuretic exposure in premature infants from 1997 to 2011.
- Effects of novel ethacrynic acid derivatives on human trabecular meshwork cell shape, actin cytoskeletal organization, and transcellular fluid flow.
- Effects of the new ethacrynic acid derivative SA9000 on intraocular pressure in cats and monkeys.
- Effects of the new ethacrynic acid oxime derivative SA12590 on intraocular pressure in cats and monkeys.
- Effects of topical ethacrynic acid adducts on intraocular pressure in rabbits and monkeys.
- Ethacrynic acid disrupts steady state microtubules in vitro.
- Ethacrynic acid induces reversible shape and cytoskeletal changes in cultured cells.
- Ethacrynic acid: acute hemodynamic effects and influence on the in vivo and in vitro response to nitroglycerin in the dog.
- Exploration of in vitro pro-drug activation and futile cycling by glutathione S-transferases: thiol ester hydrolysis and inhibitor maturation.
- Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits.
- Identification of a glutathione S-transferase without affinity for glutathione sepharose in human kidney.
- Implementation of a diuretic stewardship program in a pediatric cardiovascular intensive care unit to reduce medication expenditures.
- Improving interstitial transport of macromolecules through reduction in cell volume fraction in tumor tissues.
- Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells.
- Influence of ethacrynic acid on outflow facility in the monkey and calf eye.
- Interaction of ethacrynic acid with bovine brain tubulin.
- Microtubule disruption leads to cellular contraction in human trabecular meshwork cells.
- New ethacrynic acid derivatives as potent cytoskeletal modulators in trabecular meshwork cells.
- Numerical simulations of ethacrynic acid transport from precorneal region to trabecular meshwork.
- Ototoxic drug effects on cochlear histochemistry.
- Thiol adducts of ethacrynic acid increase outflow facility in enucleated calf eyes.
- Transscleral diffusion of ethacrynic acid and sodium fluorescein.
- What's new in diuretic therapy.
- n-ethylmaleimide and ethacrynic acid inhibit kinesin binding to microtubules in a motility assay.