Eye Diseases

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  Subject Areas on Research

  • A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome. 
  • A case of lung, eye and brain disease. 
  • A method to free retina and vitreous from intraoperative incarceration in the sclerotomy. 
  • A new phase in the study of human inherited eye diseases. 
  • A simplified method to measure choroidal thickness using adaptive compensation in enhanced depth imaging optical coherence tomography. 
  • A survey on computer aided diagnosis for ocular diseases. 
  • ASTEROID HYALITIS: A STUDY OF SERUM CALCIUM LEVELS IN AFFECTED PATIENTS. 
  • Access to care: eye care provider workforce considerations in 2020. 
  • Access to eye care: response of the American Academy of Ophthalmology and its members to societal needs now and in the future. 
  • Accuracy of international classification of diseases, ninth revision, clinical modification billing codes for common ophthalmic conditions. 
  • Aclacinomycin A in the treatment of experimental proliferative vitreoretinopathy. Efficacy and toxicity in the rabbit eye. 
  • Acquired immunodeficiency syndrome (AIDS). 
  • Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease. 
  • Agreement of Ocular Symptom Reporting Between Patient-Reported Outcomes and Medical Records. 
  • Alcohol and eye diseases. 
  • Anterior segment photography in pediatric eyes using the Lytro light field handheld noncontact camera. 
  • Antifibrotic and uveitogenic properties of gamma interferon in the rabbit eye. 
  • Artificial intelligence and deep learning in ophthalmology. 
  • Assessing the Causality between Blood Pressure and Retinal Vascular Caliber through Mendelian Randomisation. 
  • Association between anatomical resolution and functional outcomes in the mivi-trust studies using ocriplasmin to treat symptomatic vitreomacular adhesion/vitreomacular traction, including when associated with macular hole. 
  • Association of Vision Impairment and Major Eye Diseases With Mobility and Independence in a Chinese Population. 
  • Association of serum lutein and zeaxanthin with quantitative measures of retinal vascular parameters. 
  • Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies. 
  • Biofeedback techniques in the treatment of visual and ophthalmologic disorders: a review of the literature. 
  • Botulinum toxin in ophthalmology. 
  • Brand Medications and Medicare Part D: How Eye Care Providers' Prescribing Patterns Influence Costs. 
  • CMPK1 and RBP3 are associated with corneal curvature in Asian populations. 
  • Cellular composition of post-haemorrhagic opacities in the human vitreous. 
  • Characterization of Ebola Virus-Associated Eye Disease. 
  • Chemosis, proptosis and amaurosis in a 19-year-old male. 
  • Clinical Relevance and Application of the Age-Related Eye Disease Study Severity Scale for Age-Related Macular Degeneration. 
  • Clinical and pathological aspects of choroidal ischaemia. 
  • Combined phacoemulsification and pars plana vitrectomy. 
  • Contactless optical coherence tomography of the eyes of freestanding individuals with a robotic scanner. 
  • Corneal stromal overgrowth after cataract extraction. 
  • Cytologic findings in vitreous fluids. Analysis of 74 specimens. 
  • Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy. 
  • Deep learning in ophthalmology: The technical and clinical considerations. 
  • Demographic-related variations in posterior segment ocular sarcoidosis. 
  • Design of the efficacy of prednisone in the treatment of ocular myasthenia (EPITOME) trial. 
  • Determinants of image quality of Heidelberg Retina Tomography II and its association with optic disc parameters in a population-based setting. 
  • Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes. 
  • Development of ocular disease in patients with mucous membrane pemphigoid involving the oral mucosa. 
  • Development of the 25-item National Eye Institute Visual Function Questionnaire. 
  • Development, Validation, and Innovation in Ophthalmic Laser-Based Imaging: Report From a US Food and Drug Administration-Cosponsored Forum. 
  • Diagnosis and management of opacified silicone intraocular lenses in patients with asteroid hyalosis. 
  • Diagnosis of vitreoretinal adhesions in macular disease with optical coherence tomography. 
  • Diagnostic exercise: eye lesions in rats. 
  • Diagnostic tests: understanding results, assessing utility, and predicting performance. 
  • Diagnostic yield of vitrectomy in eyes with suspected posterior segment infection or malignancy. 
  • Does Aspirin Worsen Macular Degeneration in a Clinically Meaningful Way? 
  • Drusen of the optic disc. A histopathological study. 
  • Drusen of the optic disc. A retrospective study in cadaver eyes. 
  • Dynamic Imaging of a Pigmented Free-Floating Vitreous Cyst. 
  • EPITHELIAL DOWNGROWTH IN THE VITREOUS CAVITY AND ON THE RETINA IN ENUCLEATED SPECIMENS AND IN EYES WITH VISUAL POTENTIAL. 
  • Economic analysis in eye disease. 
  • Efficacy and safety of brolucizumab versus aflibercept in eyes with polypoidal choroidal vasculopathy in Japanese participants of HAWK. 
  • Efficacy of intravitreal ocriplasmin for treatment of vitreomacular adhesion: subgroup analyses from two randomized trials. 
  • Electron immunocytochemical analysis of posterior hyaloid associated with diabetic macular edema. 
  • Electron microscopic observations of intravitreal Cysticercus cellulosae (Taenia solium). 
  • Emergency department use for eye care services and future directions in care. 
  • Endogenous ocular aspergillosis. 
  • Establishing a Vision and Eye Health Surveillance System for the Nation: A Status Update on the Vision and Eye Health Surveillance System. 
  • Estimating eye care workforce supply and requirements. 
  • Evaluation for Disparities in Experience With Internet-Based Health Care Among US Patients With Chronic Eye Diseases. 
  • Experimental ocular toxocariasis: a mouse model. 
  • Experimental transvitreal cyanoacrylate retinopexy in a primate model. 
  • External ocular pigmentation. 
  • Eye Swelling and Weight Loss in an 18-year-old Adolescent. 
  • Eye Symptom Questionnaire to Evaluate Anterior Eye Health. 
  • Eye and Vision Health for Tomorrow: From Recommendations to Coordinated Action. 
  • Eye care in the United States: do we deliver to high-risk people who can benefit most from it? 
  • Eye care providers' attitudes towards tele-ophthalmology. 
  • Eye pain after vitreoretinal surgery: a prospective study of 185 patients. 
  • Fadenoperation for the management of complicated incomitant vertical strabismus. 
  • Familial variable expression of dilated cardiomyopathy in Alström syndrome: a report of four sibs. 
  • Filtering bleb thrombolysis with tissue plasminogen activator. 
  • Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial: 5. Clinical features of cytomegalovirus retinitis at diagnosis. Studies of ocular complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. 
  • From Data to Deployment: The Collaborative Community on Ophthalmic Imaging Roadmap for Artificial Intelligence in Age-Related Macular Degeneration. 
  • Future requirements for and supply of ophthalmologists for an aging population in Singapore. 
  • GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. 
  • Glove perforations in ophthalmic surgery. 
  • Glove perforations in ophthalmic surgery. 
  • Health literacy and ophthalmic patient education. 
  • High prevalence of undiagnosed eye diseases in individuals with dementia. 
  • High-risk populations for vision loss and eye care underutilization: a review of the literature and ideas on moving forward. 
  • Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy. 
  • How much eye care services do Asian populations need? Projection from the Singapore Epidemiology of Eye Disease (SEED) study. 
  • Hypertensive retinopathy revisited: some answers, more questions. 
  • ISOPT Clinical Special Issue. 
  • Identifying the content area for the 51-item National Eye Institute Visual Function Questionnaire: results from focus groups with visually impaired persons. 
  • Impact of Microscope-Integrated OCT on Ophthalmology Resident Performance of Anterior Segment Surgical Maneuvers in Model Eyes. 
  • Impact of Visual Impairment and Eye diseases on Mortality: the Singapore Malay Eye Study (SiMES). 
  • Impact of automatic infectious diseases consultation on the management of fungemia at a large academic medical center. 
  • Impact of migration and acculturation on prevalence of type 2 diabetes and related eye complications in Indians living in a newly urbanised society. 
  • Impact of systemic vascular risk factors on the choriocapillaris using optical coherence tomography angiography in patients with systemic hypertension. 
  • Improvement in efficacy of corticosteroid therapy in an animal model of proliferative vitreoretinopathy by pretreatment. 
  • Induction and Characterization of the Allergic Eye Disease Mouse Model. 
  • Inpatient Ophthalmology Consultations. 
  • Into the looking glass: factors and opportunities to reshape eye care in the next 25 years. 
  • Intraocular lens complications requiring removal or exchange. 
  • Intraoperative ketorolac and eye pain after viteoretinal surgery: a prospective, randomized, placebo-controlled study. 
  • Intravitreal liposome-encapsulated drugs: a preliminary human report. 
  • Iris vasculopathy in exfoliation syndrome. An immunocytochemical study. 
  • Iron homeostasis and eye disease. 
  • Is informed consent needed for fluorescein angiography? 
  • Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways. 
  • LASIK and vitreous pathology after LASIK. 
  • Language barrier and its relationship to diabetes and diabetic retinopathy. 
  • Laser therapy for diseases of the eye. 
  • Linking immune responses with fibrosis in allergic eye disease. 
  • Long term effects and quality of life in children and adults after marrow transplantation. 
  • Long-term results of successful vitrectomy with silicone oil for advanced proliferative vitreoretinopathy. 
  • Longitudinal analysis of the relationship between regular eye examinations and changes in visual and functional status. 
  • MPS VI associated ocular phenotypes in an MPS VI murine model and the therapeutic effects of odiparcil treatment. 
  • Major eye diseases and risk factors associated with systemic hypertension in an adult Chinese population: the Beijing Eye Study. 
  • Management of anterior vitreous traction in proliferative vitreoretinopathy. 
  • Mapping standard ophthalmic outcome sets to metrics currently reported in eight eye hospitals. 
  • Matrix metalloproteinases and their inhibitors in human vitreous. 
  • Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy. 
  • Measuring access to eye care: a public health perspective. 
  • Measuring outcomes in chronic diseases: ready for prime time? 
  • Mechanistic Effects of Baicalein on Aqueous Humor Drainage and Intraocular Pressure. 
  • Meeting report of the American Ophthalmological Society, 131st year annual meeting, Hot Springs, Va, May 21-24, 1995. 
  • Metabolic syndrome and eye diseases. 
  • Methodology of the Singapore Indian Chinese Cohort (SICC) eye study: quantifying ethnic variations in the epidemiology of eye diseases in Asians. 
  • Methods, statistical features, and baseline results of a standardized, multicentered ophthalmologic surgical trial: the Silicone Study. 
  • Microgravity-induced ocular changes in astronauts: a sight odyssey. 
  • Monitoring visual status: why patients do or do not comply with practice guidelines. 
  • Monoclonal Antibodies, Derived from Humans Vaccinated with the RV144 HIV Vaccine Containing the HVEM Binding Domain of Herpes Simplex Virus (HSV) Glycoprotein D, Neutralize HSV Infection, Mediate Antibody-Dependent Cellular Cytotoxicity, and Protect Mice from Ocular Challenge with HSV-1. 
  • Morphologic criteria for the preliminary identification of Fusarium, Paecilomyces, and Acremonium species by histopathology. 
  • Multiple ocular diseases detection based on joint sparse multi-task learning. 
  • Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 
  • Myeloperoxidase-Antineutrophil Cytoplasmic Antibody (ANCA)-Positive and ANCA-Negative Patients With Granulomatosis With Polyangiitis (Wegener's): Distinct Patient Subsets. 
  • Myopia predicts better outcome in persistent hyperplastic primary vitreous. 
  • Myopia-related fundus changes in Singapore adults with high myopia. 
  • N,N-dimethyladriamycin for treatment of experimental proliferative vitreoretinopathy: efficacy and toxicity on the rabbit retina. 
  • N-3-pyridylmethyl-N'-p-nitrophenylurea ocular toxicity in man and rabbits. 
  • NEIBank: genomics and bioinformatics resources for vision research. 
  • Neural misdirection in congenital ocular fibrosis syndrome: implications and pathogenesis. 
  • Neuro-ophthalmic side effects of molecularly targeted cancer drugs. 
  • Neuro-ophthalmology Safer Than MRI? 
  • Neurocutaneous melanosis in association with encephalocraniocutaneous lipomatosis. 
  • Novel Scoring Criteria for the Evaluation of Ocular Graft-versus-Host Disease in a Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Animal Model. 
  • ORBIS telemedicine users. 
  • Obesity and eye diseases. 
  • Ocular associations of diabetes other than diabetic retinopathy. 
  • Ocular complications after anti-vascular endothelial growth factor therapy in Medicare patients with age-related macular degeneration. 
  • Ocular effects in acquired immune deficiency syndrome. 
  • Ocular manifestations and concepts of systemic vasculitides. 
  • Ocular manifestations of ANCA-associated vasculitis. 
  • Ocular manifestations of multiple myeloma, Waldenström's macroglobulinemia and benign monoclonal gammopathy. 
  • Ocular manifestations of patients receiving heart transplants: a single-center experience of 311 consecutive cases. 
  • Ocular manifestations of preeclampsia. 
  • Ocular pathology in rainbow trout in Malawi (Zomba disease). 
  • Ocular pathology of Fabry's disease in a hemizygous male following renal transplantation. 
  • Ocular rosacea in blacks. 
  • Ocular rosacea. 
  • Ocular toxicity of daunomycin: effects of subdivided doses on the rabbit retina after vitreous gas compression. 
  • Ophthalmic Immune-Related Adverse Events of Immunotherapy: A Single-Site Case Series. 
  • Ophthalmic Medication Expenditures and Out-of-Pocket Spending: An Analysis of United States Prescriptions from 2007 through 2016. 
  • Ophthalmologic findings in Cornelia de Lange syndrome: a genotype-phenotype correlation study. 
  • Optical coherence tomography to detect macular edema in the presence of asteroid hyalosis. 
  • Patient expectations regarding eye care: development and results of the Eye Care Expectations Survey (ECES). 
  • Perceptions of Respect From Clinicians by Patients in Racial and Ethnic Minority Groups With Eye Disease. 
  • Phthisis after endoscopic cyclophotocoagulation. 
  • Postoperative fibrin formation and visual outcome after pars plana vitrectomy. 
  • Preretinal and intraretinal exudates in familial exudative vitreoretinopathy. 
  • Prevalence and causes of low vision and blindness in a rural chinese adult population: the Handan Eye Study. 
  • Prevalence and causes of vision loss in Central and South Asia: 1990-2010. 
  • Prevalence and causes of vision loss in East Asia: 1990-2010. 
  • Prevalence and causes of vision loss in Latin America and the Caribbean: 1990-2010. 
  • Prevalence and causes of vision loss in North Africa and the Middle East: 1990-2010. 
  • Prevalence and causes of vision loss in Southeast Asia and Oceania: 1990-2010. 
  • Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe: 1990-2010. 
  • Prevalence and causes of vision loss in sub-Saharan Africa: 1990-2010. 
  • Prevalence and causes of visual impairment and blindness in an urban Indian population: the Singapore Indian Eye Study. 
  • Prevalence of major eye diseases among US Civil War veterans, 1890-1910 
  • Prevalence, Risk Factors, and Impact of Undiagnosed Visually Significant Cataract: The Singapore Epidemiology of Eye Diseases Study. 
  • Prevalence, diagnostic features, and response to trabeculectomy in exfoliation glaucoma. 
  • Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal implant for the sustained release of fluorouracil. 
  • Projection of Eye Disease Burden in Singapore. 
  • Psychometric properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ). NEI-VFQ Field Test Investigators. 
  • Quantitative assessment of growth stimulating activity of the vitreous during PVR. 
  • Racial differences and determinants of macular thickness profiles in multiethnic Asian population: the Singapore Epidemiology of Eye Diseases Study. 
  • Rationale and methodology for a population-based study of eye diseases in Malay people: The Singapore Malay eye study (SiMES). 
  • Rationale, design, methodology, and baseline data of a population-based study in rural China: the Handan Eye Study. 
  • Receipt of Eye Care Services among Medicare Beneficiaries with and without Dementia. 
  • Recruitment of Donor T Cells to the Eyes During Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell Transplants. 
  • Red reflex examination in infants. Section on Ophthalmology. American Academy of Pediatrics. 
  • Referable Macular Hemorrhage-A Clinically Meaningful Screening Target in Newborn Infants. Position Statement of the Association of Pediatric Retina Surgeons. 
  • Removal of intravitreous cysticerci from the surface of the optic nervehead. A pars plana approach. 
  • Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model. 
  • Results of silicone oil removal in advanced proliferative vitreoretinopathy. 
  • Retinal pigment epithelial tear with vitreomacular attachment: a novel pathogenic feature. 
  • Retinal vascular caliber measurements: clinical significance, current knowledge and future perspectives. 
  • Retinal vascular fractal dimension and its relationship with cardiovascular and ocular risk factors. 
  • Retinopathy of prematurity: late complications in the baby boomer generation (1946-1964). 
  • Review of key findings from the Singapore Malay Eye Study (SiMES-1). 
  • Risk factors for postvitrectomy fibrin formation. 
  • Role of high resolution optical coherence tomography in diagnosing ocular surface squamous neoplasia with coexisting ocular surface diseases. 
  • Sarcoidosis and its ophthalmic manifestations. 
  • Screening tests in a clinic population. 
  • Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease. 
  • Sensitivity, specificity, and predictive values of screening tests for eye conditions in a clinic-based population. 
  • Silicone oil for progressive anterior ocular neovascularization after failed diabetic vitrectomy. 
  • Silicone oil for retinal detachment with advanced proliferative vitreoretinopathy following failed vitrectomy for proliferative diabetic retinopathy. 
  • Silicone oil in vitreoretinal surgery. Part 1: Surgical techniques. 
  • Singapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes. 
  • Singapore Malay Eye Study: rationale and methodology of 6-year follow-up study (SiMES-2). 
  • Socioeconomic disparity in use of eye care services among US adults with age-related eye diseases: National Health Interview Survey, 2002 and 2008. 
  • Spectrum of ocular toxicities from epidermal growth factor receptor inhibitors and their intermediate-term follow-up: a five-year review. 
  • Successfully treated postoperative Candida parakrusei endophthalmitis. 
  • Telemedicine for ophthalmic consultation services: use of a portable device and layering information for graders. 
  • The "T" in JOPT. 
  • The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases. 
  • The Effects of Lighting Problems on Eye Symptoms among Cleanroom Microscope Workers. 
  • The Relationship of Visiting Alternative Care Practitioners with Receiving Medical Eye Care in Patients with Chronic Ocular Disease. 
  • The effect of combined daunorubicin and triamcinolone acetonide treatment on a refined experimental model of proliferative vitreoretinopathy. 
  • The effects of silicone oil removal. Silicone Study Report 6. 
  • The eye: A window to the soul of the immune system. 
  • The eye: a window of opportunity in rheumatoid arthritis? 
  • The eyes as a window to improved understanding of the prenatal effects of Zika virus infection. 
  • The incidence of neuro-ophthalmic diseases in Singapore: a prospective study in public hospitals. 
  • The nonapproved use of medications. 
  • The ocular manifestations of Wegener's granulomatosis. Fifteen years experience and review of the literature. 
  • The test light affects quantitation of the afferent pupillary defect. 
  • The use of optical coherence tomography in intraoperative ophthalmic imaging. 
  • The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy. 
  • The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy. 
  • Treatment of postvitrectomy fibrin formation with intraocular tissue plasminogen activator. 
  • Trends in the pattern of blindness and major ocular diseases in Singapore and Asia. 
  • Tug of war. 
  • Twins eye study in Tasmania (TEST): rationale and methodology to recruit and examine twins. 
  • Understanding the critical importance of diagnosis in the measurement of quality of care. 
  • Unexpected autopsy findings arising from postmortem ocular examination. 
  • Unusual complications of antipsychotic drugs. 
  • Use of eye care services among the 1991 Medicare population. 
  • Use of health care claims data to study patients with ophthalmologic conditions. 
  • Use of the ICD-10 vision codes to study ocular conditions in Medicare beneficiaries with stroke. 
  • Vision impairment and major causes of vision loss impacts on vision-specific functioning independent of socioeconomic factors. 
  • Vision impairment and major eye diseases reduce vision-specific emotional well-being in a Chinese population. 
  • Vision surveillance in the United States: has the time come? 
  • Visual Impairment in Old and Very Old Community-dwelling Asian Adults. 
  • Visual impairment, age-related eye diseases, and cognitive function: the Singapore Malay Eye study. 
  • Vitrectomy for vitreomacular traction syndrome with macular detachment. 
  • Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy. Silicone Study Report 3. 
  • Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 2. 
  • Vitrectomy with silicone oil or sulfur hexafluoride gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 1. 
  • Vitreous hemorrhage after intracranial hemorrhage. 
  • Vitreous membrane formation after experimental vitreous haemorrhage. 
  • Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. 
  • Weighted least-squares approach for comparing correlated kappa. 
  • Work time estimates for ophthalmic diagnoses and procedures. Results from the Eye Care Workforce Study. 
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  Keywords of People

  • Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
  • Busuioc, Corina Adela, Medical Instructor in the Department of Ophthalmology, Ophthalmology, Corneal Diseases
  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Fekrat, Sharon, Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery
  • Mruthyunjaya, Prithvi, Adjunct Associate Professor in the Department of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering