-
Subject Areas on Research
-
A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.
-
ABO blood group influences transfusion and survival after cardiac surgery.
-
Angiogenesis as a predictor of survival after surgical resection for stage I non-small-cell lung cancer.
-
Anticoagulation monitoring during pediatric extracorporeal membrane oxygenation.
-
Assessing patients' and caregivers' perspectives on stability of factor VIII products for haemophilia A: a web-based study in the United States and Canada.
-
Association of fibrinogen and coagulation factors VII and VIII with cardiovascular risk factors in the elderly: the Cardiovascular Health Study. Cardiovascular Health Study Investigators.
-
Binding of factor VIII inhibitors to discrete regions of the factor VIII C2 domain disrupt phospholipid binding.
-
Bovine retinal explants cultured in collagen gels. A model system for the study of proliferative retinopathy.
-
Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues.
-
Cellular interactions in hemostasis.
-
Circulating anticoagulants to factor VIII. Immunochemical studies and clinical response to factor VIII concentrates.
-
Cloned endothelium derived from autoimmune vascular disease retain structural and functional characteristics of normal endothelial cells.
-
Coagulopathy after cardiopulmonary bypass in Jehovah's Witness patients: management of two cases using fractionated components and factor VIIa.
-
Contemporary issues in the management of von Willebrand disease.
-
Contributions of Asn2198, Met2199, and Phe2200 in the factor VIII C2 domain to cofactor activity, phospholipid-binding, and von Willebrand factor-binding.
-
Cryoprecipitate therapy.
-
Cryoprecipitate transfusion in bleeding patients.
-
Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets.
-
Effect of heterologous factor V heavy chain sequences on the secretion of recombinant human factor VIII.
-
Electron microscopy of human factor VIII/Von Willebrand glycoprotein: effect of reducing reagents on structure and function.
-
Elevated factor VIII enhances thrombin generation in the presence of factor VIII-deficiency, factor XI-deficiency or fondaparinux.
-
Endothelial cell surface expression and binding of factor VIII/von Willebrand factor.
-
Evaluation of a modified procedure for Staclot LA for the confirmation of lupus anticoagulants.
-
Excess factor VIII and hypercoagulability.
-
Experimental transfusion reactions and disseminated intravascular coagulation produced by incompatible plasma in monkeys.
-
Factor VIII Arg2304 --> His binds to phosphatidylserine and is a functional cofactor in the factor X-ase complex.
-
Factor VIII/von Willebrand protein. Modification of its carbohydrate causes reduced binding to platelets.
-
Fibrinogen and factor VIII, but not factor VII, are associated with measures of subclinical cardiovascular disease in the elderly. Results from The Cardiovascular Health Study.
-
Fibrinogen and hemostasis: a primary hemostatic target for the management of acquired bleeding.
-
Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy.
-
Fibrinogen content of low-volume cryoprecipitate.
-
Gene therapies for hemophilia hit the mark in clinical trials.
-
Global sources of cryoprecipitate demonstrate variability in coagulant factor levels and functional hemostasis.
-
HTLV-III seroconversion associated with heat-treated factor VIII concentrate.
-
Haemostasis: from bench to bedside.
-
Hepatitis C infection in children with hemophilia A and B.
-
Human splenic sinusoidal lining cells express antigens associated with monocytes, macrophages, endothelial cells, and T lymphocytes.
-
Hypercoagulable states and antithrombotic strategies in recurrent vascular access site thrombosis.
-
Immune hemolytic transfusion reactions in monkeys: activation of the kallikrein system.
-
Immunohistochemical studies of cell differentiation in a juxtaglomerular tumor.
-
Increased number of coagulation products in relationship to red blood cell products transfused improves mortality in trauma patients.
-
Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
-
Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: the multi-ethnic study of atherosclerosis.
-
Inhibitory anti-factor V antibodies bind to the factor V C2 domain and are associated with hemorrhagic manifestations.
-
Inhibitory effect of ristocetin and factor VIII/von Willebrand factor protein on human platelet adenylate cyclase activity.
-
Intracerebral hematoma in a hemophiliac. Combined surgical and factor VIII treatment.
-
Intraretinal neovascularization in diabetic retinopathy.
-
Is there a precursive, relatively procoagulant-inactive form of normal antihemophilic factor (factor VIII)?
-
Isolated vocal cord hematoma in a child with severe factor VIII deficiency.
-
Isolation and purification of canine adipose microvascular endothelial cells.
-
Lack of thromboxane A2 synthesis in platelet aggregation induced by factor VIII/von Willebrand factor.
-
Localization of factor VIII/von Willebrand factor and glial fibrillary acidic protein in the hemangioblastoma: implications for stromal cell histogenesis.
-
Lymph node infarction: role of underlying malignancy, tumour proliferation fraction and vascular compromise--a study of 35 cases and a comprehensive review of the literature.
-
Management of a patient with type IIC von Willebrand's disease during coronary artery bypass graft surgery.
-
Microvascular injury and blood-brain barrier leakage in Alzheimer's disease.
-
Modulation of platelet shape and membrane receptor binding by Ca2+-calmodulin complex.
-
Phospholipid vesicles interfere with the binding of antibody fragments to the light chain of factor VIII.
-
Platelet heterogeneity: variation in coagulation complexes on platelet subpopulations.
-
Platelet procoagulant complex assembly in a tissue factor-initiated system.
-
Platelet receptors for human Factor VIII/von Willebrand protein: functional correlation of receptor occupancy and ristocetin-induced platelet aggregation.
-
Procoagulant and platelet aggregating properties of antilymphocyte sera.
-
Reduction in blood transfusion in a cohort of infants having cardiac surgery with cardiopulmonary bypass after instituting a goal-directed transfusion policy.
-
Reduction of human prostate tumor vascularity by the alpha1-adrenoceptor antagonist terazosin.
-
Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein.
-
Safety and efficacy of turoctocog alfa (NovoEight®) during surgery in patients with haemophilia A: results from the multinational guardian™ clinical trials.
-
Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation.
-
Specificity and sensitivity of immunohistochemical detection of factor VIII/von Willebrand factor antigen in formalin-fixed paraffin-embedded tissue.
-
Spontaneous factor VIII inhibitor occurring in association with chronic graft-versus-host disease.
-
Spontaneously acquired anti-factor VIII antibodies: report of a patient with adenocarcinoma of the prostate.
-
Successful prophylactic regimens for transvaginal oocyte retrieval in women with bleeding diatheses.
-
Sustained expression of human factor VIII in mice using a parvovirus-based vector.
-
The anticoagulant effect of protamine sulfate is attenuated in the presence of platelets or elevated factor VIII concentrations.
-
The basis for the increase in factor VIII procoagulant activity during exercise.
-
The bleeding diathesis in human glycogen storage disease type I: in vitro identification of a naturally occurring inhibitor of ristocetin-induced platelet aggregation.
-
The characterization of twenty sequenced human genomes.
-
The prognosis and treatment of acquired hemophilia: a systematic review and meta-analysis.
-
The subunit structure of normal and hemophilic factor VIII.
-
Thrombin activates factor XI on activated platelets in the absence of factor XII.
-
Thrombin generation and fibrinolysis in anti-factor IX treated blood and plasma spiked with factor VIII inhibitor bypassing activity or recombinant factor VIIa.
-
Total knee arthroplasty in hemophilia.
-
Two classes of germline genes both derived from the V(H)1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII.
-
Venous thrombosis in a family with defective release of vascular plasminogen activator and elevated plasma factor VIII/von Willebrand's factor.
-
Von Willebrand disease and other bleeding disorders in women: consensus on diagnosis and management from an international expert panel.
-
von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA).
-
von Willebrand disease in the 21st century: current approaches and new challenges.
-
Keywords of People
-
Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
-
Hoffman, Maureane,
Professor of Pathology,
Immunology
-
Lagoo, Anand Shreeram,
Professor of Pathology,
Pathology
-
Levy, Jerrold Henry,
Professor of Anesthesiology,
Anesthesiology, Cardiothoracic
-
Milano, Carmelo Alessio,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Surgery, Cardiovascular and Thoracic Surgery
-
O'Connor, Christopher Michael,
Richard Sean Stack, M.D. Distinguished Professor,
Medicine, Clinical Pharmacology