Fanconi Anemia
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Subject Areas on Research
- Abnormalities in glucose tolerance are common in children with fanconi anemia and associated with impaired insulin secretion.
- Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.
- Decompressive hemicraniectomy in pediatric patients with malignant middle cerebral artery infarction: case series and review of the literature.
- Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.
- FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: activation is not required for repair of Cr(VI)-induced DSBs.
- Fanconi anemia complementation group A cells are hypersensitive to chromium(VI)-induced toxicity.
- Fanconi anemia gene variants in therapy-related myeloid neoplasms.
- Fanconi's anemia in adulthood: chemoradiation-induced bone marrow failure and a novel FANCA mutation identified by targeted deep sequencing.
- Fanconi's anemia treated by allogeneic marrow transplantation.
- Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival.
- Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-identical sibling.
- High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7's induction of DNA damage response, an activity mediated by E7's inactivation of pocket proteins.
- Human umbilical cord blood: a clinically useful source of transplantable hematopoietic stem/progenitor cells.
- Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers.
- Infantile glaucoma associated with the Diamond-Blackfan syndrome.
- Interaction of FANCD2 and NBS1 in the DNA damage response.
- Late effects in patients with Fanconi anemia following allogeneic hematopoietic stem cell transplantation from alternative donors.
- Long-term survival and cure after marrow transplantation for congenital hypoplastic anaemia (Diamond-Blackfan syndrome).
- Loss of Dependence on Continued Expression of the Human Papillomavirus 16 E7 Oncogene in Cervical Cancers and Precancerous Lesions Arising in Fanconi Anemia Pathway-Deficient Mice.
- Lymphoblastic lymphoma and excessive toxicity from chemotherapy: an unusual presentation for Fanconi anemia.
- Malignancies after marrow transplantation for aplastic anemia and fanconi anemia: a joint Seattle and Paris analysis of results in 700 patients.
- Marrow transplantation for Fanconi anaemia: conditioning with reduced doses of cyclophosphamide without radiation.
- Marrow transplantation for Fanconi anemia with or without leukemic transformation: an update of the Seattle experience.
- Marrow transplantation for disorders of hematopoiesis.
- Mobilization and collection of peripheral blood CD34+ cells from patients with Fanconi anemia.
- Outcome of domino hematopoietic stem cell transplantation in human subjects: An international case series.
- Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo.
- Results of unrelated cord blood transplant in fanconi anemia patients: risk factor analysis for engraftment and survival.
- Stem cell transplantation for the treatment of Fanconi anaemia using a fludarabine-based cytoreductive regimen and T-cell-depleted related HLA-mismatched peripheral blood stem cell grafts.
- Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation.
- Umbilical cord blood: a novel alternative source of hematopoietic stem cells for bone marrow transplantation.