Fasting

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  Subject Areas on Research

  • A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. 
  • A comparison of two very-low-calorie diets: protein-sparing-modified fast versus protein-formula-liquid diet. 
  • A complementary care study combining flaxseed oil, caffeine, fasting, and exercise in women diagnosed with advanced ovarian cancer: findings from a case study. 
  • A generic emergency protocol for patients with inborn errors of metabolism causing fasting intolerance: A retrospective, single-center study and the generation of www.emergencyprotocol.net. 
  • A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. 
  • A rodent model of rapid-onset diabetes induced by glucocorticoids and high-fat feeding. 
  • Abnormal Fasting Glucose Increases Risk of Unrecognized Myocardial Infarctions in an Elderly Cohort. 
  • Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. 
  • Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen. 
  • Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase. 
  • Adverse metabolic response to regular exercise: is it a rare or common occurrence? 
  • Alkaline ribonuclease in rat liver: effect of hypophysectomy and fasting. 
  • American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Nutrition Screening and Therapy Within a Surgical Enhanced Recovery Pathway. 
  • Analytical performance and clinical utility of a direct LDL-cholesterol assay in a hyperlipidemic pediatric population. 
  • Androgen-deprivation therapy and metabolic syndrome in men with prostate cancer. 
  • Association of Roadway Proximity with Fasting Plasma Glucose and Metabolic Risk Factors for Cardiovascular Disease in a Cross-Sectional Study of Cardiac Catheterization Patients. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Associations between central nervous system serotonin, fasting glucose, and hostility in African American females. 
  • Baseline factors associated with glycaemic response to treatment with once-weekly dulaglutide in patients with type 2 diabetes. 
  • Blood glucose levels and cortical thinning in cognitively normal, middle-aged adults. 
  • CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability. 
  • Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial. 
  • Cardiovascular risk factors and retinal microvascular signs in an adult Japanese population: the Funagata Study. 
  • Central Nervous System GLP-1 Receptors Regulate Islet Hormone Secretion and Glucose Homeostasis in Male Rats. 
  • Change in metabolic syndrome parameters with antipsychotic treatment in the CATIE Schizophrenia Trial: prospective data from phase 1. 
  • Changes in depressive symptoms and glycemic control in diabetes mellitus. 
  • Changes in hunger and fullness in relation to gut peptides before and after 8 weeks of alternate day fasting. 
  • Changes in pancreatic tryptophan in the rat in response to fasting. The effect of B-cytotoxic agents and variation through the oestrous cycle. 
  • Characterization of a canine model of glycogen storage disease type IIIa. 
  • Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. 
  • Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines. 
  • Comparison of low- and high-carbohydrate diets for type 2 diabetes management: a randomized trial. 
  • Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis. 
  • Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. 
  • Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia. 
  • Determinants of weight loss success with alternate day fasting. 
  • Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. 
  • Dietary macronutrient regulation of acyl and desacyl ghrelin concentrations in children with Prader-Willi syndrome (PWS). 
  • Dietary protein adequacy and lower body versus whole body resistive training in older humans. 
  • Dietary regulation of glucose-dependent insulinotropic peptide (GIP) gene expression in rat small intestine. 
  • Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans. 
  • Do children with recurrent abdominal pain grow up to become adolescents who control their weight by fasting? Results from a UK population-based cohort. 
  • Doppler US measurement of portal venous flow: variability in healthy fasting volunteers. 
  • Early pregnancy insulin resistance and subsequent gestational diabetes mellitus. 
  • Eating behavior traits of successful weight losers during 12 months of alternate-day fasting: An exploratory analysis of a randomized controlled trial. 
  • Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial. 
  • Effect of a community-based weight management program on weight loss and cardiovascular disease risk factors. 
  • Effect of a low-carbohydrate, ketogenic diet program compared to a low-fat diet on fasting lipoprotein subclasses. 
  • Effect of apolipoproteins on the induction of hepatic steatosis in rats. 
  • Effect of dietary patterns on serum homocysteine: results of a randomized, controlled feeding study. 
  • Effect of fasting and feeding on measurement of carbon dioxide production using doubly labeled water. 
  • Effect of fasting on the VO2-fh relationship in king penguins, Aptenodytes patagonicus. 
  • Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36. 
  • Effect of intermittent fasting on prostate cancer tumor growth in a mouse model. 
  • Effect of ramipril on the incidence of diabetes. 
  • Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in middle-aged men. 
  • Effect of somatostatin-28 on dynamics of insulin secretion in perfused rat pancreas. 
  • Effect of the volume and intensity of exercise training on insulin sensitivity. 
  • Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans. 
  • Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status. 
  • Effects of alternate-day fasting or daily calorie restriction on body composition, fat distribution, and circulating adipokines: Secondary analysis of a randomized controlled trial. 
  • Effects of bombesin on fasting bile formation. 
  • Effects of fasting, refeeding, and intraluminal triglyceride on proglucagon expression in jejunum and ileum. 
  • Effects of potassium supplements on glucose metabolism in African Americans with prediabetes: a pilot trial. 
  • Effects of serotonin on canine bile formation. 
  • Efficacy and safety of acarbose in metformin-treated patients with type 2 diabetes. 
  • Elevated preoperative fasting serum glucose levels increase the risk of postoperative mediastinitis in patients undergoing open heart surgery. 
  • Elevation of fasting morning glucose relative to hemoglobin A1c in normoglycemic patients treated with niacin and with statins. 
  • Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons. 
  • Emerging risk factors as markers for carotid intima media thickness scores. 
  • Evaluation and clinical application of a direct low-density lipoprotein cholesterol assay in normolipidemic and hyperlipidemic adults. 
  • Evidence for metabolic and endocrine abnormalities in subjects recovered from anorexia nervosa. 
  • Exaggerated peripheral responses to catecholamines contributes to stress-induced hyperglycemia in the ob/ob mouse. 
  • Exogenous neuropeptide Y blocks myoelectric activity in the upper gastrointestinal tract of starved dogs. Brain neuropeptide Y converts a fasting pattern of myoelectric activity to a fed pattern. 
  • Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators. 
  • Fasting Glucose Variability in Young Adulthood and Cognitive Function in Middle Age: The Coronary Artery Risk Development in Young Adults (CARDIA) Study. 
  • Fasting and postprandial concentrations of GLP-1 in intestinal lymph and portal plasma: evidence for selective release of GLP-1 in the lymph system. 
  • Fasting and postprandial concentrations of somatostatin-28 and somatostatin-14 in type II diabetes in men. 
  • Fasting before surgery. 
  • Fasting glucose, NT-proBNP, treatment with eptifibatide, and outcomes in non-ST-segment elevation acute coronary syndromes: An analysis from EARLY ACS. 
  • Fasting might not be necessary before lipid screening: a nationally representative cross-sectional study. 
  • Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid. 
  • Fasting times in serum PSA assay. 
  • Frequency of abnormal carbohydrate metabolism and diabetes in a population-based screening of adolescents. 
  • GLP-1 Receptor Blockade Reduces Stimulated Insulin Secretion in Fasted Subjects With Low Circulating GLP-1. 
  • Gastric bypass surgery restores meal stimulation of the anorexigenic gut hormones glucagon-like peptide-1 and peptide YY independently of caloric restriction. 
  • Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians. 
  • Ghrelin and Obesity: Identifying Gaps and Dispelling Myths. A Reappraisal. 
  • Glucose Activates Vagal Control of Hyperglycemia and Inflammation in Fasted Mice. 
  • Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin. 
  • Glycemic thresholds for diabetes-specific retinopathy: implications for diagnostic criteria for diabetes. 
  • Glycohemoglobin not as predictive as fasting glucose as a measure of prediabetes in predicting proteinuria. 
  • Hormonal and metabolic effects of carbohydrate restriction in children with Prader-Willi syndrome. 
  • Hostility and minimal model of glucose kinetics in African American women. 
  • Hyperglycemia, obesity, and cancer risks on the horizon. 
  • Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies. 
  • Impact of activated vitamin D on insulin resistance in nondiabetic chronic kidney disease patients. 
  • Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study. 
  • Impaired beta-cell sensitivity to glucose and maximal insulin secretory capacity in adolescents with type 2 diabetes. 
  • Impaired glucose tolerance, but not impaired fasting glucose, is associated with retinopathy in Japanese population: the Funagata study. 
  • Implications of the Hemoglobin Glycation Index on the Diagnosis of Prediabetes and Diabetes. 
  • Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha. 
  • Influence of a 3.5 day fast on physical performance. 
  • Influence of fasting on carbohydrate and fat metabolism during rest and exercise in men. 
  • Inhibition of basal and meal-stimulated choleresis by somatostatin. 
  • Insulin Sensitivity and β-Cell Function Improve after Gastric Bypass in Severely Obese Adolescents. 
  • Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. 
  • Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings. 
  • Intraventricular CCK-8 reduces single meal size in the baboon by interaction with type-A CCK receptors. 
  • Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques. 
  • Is GLP-1 a hormone: Whether and When? 
  • Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose? 
  • Is there a glycemic threshold for impaired autonomic control? 
  • Isolation and nucleotide sequence of canine glucose-6-phosphatase mRNA: identification of mutation in puppies with glycogen storage disease type Ia. 
  • Kruppel-like factor 15 is required for the cardiac adaptive response to fasting. 
  • Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study. 
  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. 
  • Leptin metabolically licenses T cells for activation to link nutrition and immunity. 
  • Leucine metabolism during fasting and exercise. 
  • Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. 
  • Long-term exposure to ambient fine particulate matter and fasting blood glucose level in a Chinese elderly cohort. 
  • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. 
  • Luminal epidermal growth factor preserves mucosal mass of small bowel in fasting rats. 
  • Maternal and child nutritional supplementation are inversely associated with fasting plasma glucose concentration in young Guatemalan adults. 
  • Meal timing during alternate day fasting: Impact on body weight and cardiovascular disease risk in obese adults. 
  • Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. 
  • Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients. 
  • Metabolic effects of repeated weight loss and regain in adolescent wrestlers 
  • Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia. 
  • Metabolic network failures in Alzheimer's disease: A biochemical road map. 
  • Metabolic profiling in Prader-Willi syndrome and nonsyndromic obesity: sex differences and the role of growth hormone. 
  • Metabolism and thermoregulation during fasting in king penguins, Aptenodytes patagonicus, in air and water. 
  • Mouse handling limits the impact of stress on metabolic endpoints. 
  • Mouse model of glycogen storage disease type III. 
  • Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis. 
  • NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding. 
  • Neighborhood characteristics moderate effects of caregiving on glucose functioning. 
  • Neurotensin releases norepinephrine differentially from perfused hypothalamus of sated and fasted rat. 
  • New prognostic model for extranodal natural killer/T cell lymphoma, nasal type. 
  • Nitric oxide, malaria, and anemia: inverse relationship between nitric oxide production and hemoglobin concentration in asymptomatic, malaria-exposed children. 
  • Nutrition for the diabetic pregnant woman. 
  • Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice. 
  • Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. 
  • Perioperative Fluid Therapy for Major Surgery. 
  • Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats. 
  • Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial. 
  • Physical activity, television viewing time, and retinal vascular caliber. 
  • Placental lactogen receptors in maternal sheep liver: effects of fasting and refeeding. 
  • Placental transport of free palmitic and linoleic acids in the guinea pig. 
  • Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men. 
  • Plasma epinephrine predicts fasting glucose in centrally obese African-American women. 
  • Plasma lactate as a marker of metabolic health: Implications of elevated lactate for impairment of aerobic metabolism in the metabolic syndrome. 
  • Predictors of target organ damage in hypertensive blacks and whites. 
  • Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance. 
  • Prevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study. 
  • Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III. 
  • Prospective association between fasting NEFA and type 2 diabetes: impact of post-load glucose. 
  • Recombinant glucagon-like peptide-1 (7-36 amide) lowers fasting serum glucose in a broad spectrum of patients with type 2 diabetes. 
  • Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling. 
  • Regulation and localization of the insulin-like growth factor system in small bowel during altered nutrient status. 
  • Regulation of cholecystokinin gene expression in rat intestine. 
  • Regulation of gastric emptying in humans by cholecystokinin. 
  • Regulation of lipoprotein lipase activity and mRNA in the mammary gland of the lactating mouse. 
  • Relations of insulin sensitivity to longitudinal blood pressure tracking: variations with baseline age, body mass index, and blood pressure. 
  • Retinal vascular caliber and the long-term risk of diabetes and impaired fasting glucose: the Blue Mountains Eye Study. 
  • Reversal of diet-induced glucose intolerance by hepatic expression of a variant glycogen-targeting subunit of protein phosphatase-1. 
  • SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. 
  • SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. 
  • SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism. 
  • Safety of alternate day fasting and effect on disordered eating behaviors. 
  • Self-reported symptoms of sleep disturbance and inflammation, coagulation, insulin resistance and psychosocial distress: evidence for gender disparity. 
  • Serum FGF23 levels in normal and disordered phosphorus homeostasis. 
  • Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification. 
  • Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. 
  • Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation. 
  • Skeletal muscle protein synthesis and the abundance of the mRNA translation initiation repressor PDCD4 are inversely regulated by fasting and refeeding in rats. 
  • Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition. 
  • Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood. 
  • Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis. 
  • Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 
  • TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. 
  • The Clinical Antipsychotic Trials Of Intervention Effectiveness (CATIE) Schizophrenia Trial: clinical comparison of subgroups with and without the metabolic syndrome. 
  • The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes. 
  • The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci. 
  • The Pediatric Obesity Microbiome and Metabolism Study (POMMS): Methods, Baseline Data, and Early Insights. 
  • The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample. 
  • The anorectic effect of GLP-1 in rats is nutrient dependent. 
  • The effect of an amino acid-lowering diet on the rate of melphalan entry into brain and xenotransplanted glioma. 
  • The effect of zinc deficiency and food restriction on prostaglandin E2 and thromboxane B2 in saliva and plasma of rats. 
  • The hepatic extraction of gastric inhibitory polypeptide and insulin. 
  • The malnourished surgery patient: a silent epidemic in perioperative outcomes? 
  • The placental lactogen receptor in maternal and fetal sheep liver: regulation by glucose and role in the pathogenesis of fasting during pregnancy. 
  • The preparation and properties of an antiserum for the radioimmunoassay of serum conjugated cholic acid. 
  • The relation of free plasma tryptophan to anger, hostility, and aggression in a nonpatient sample of adult men and women. 
  • The role of dysregulated glucagon secretion in type 2 diabetes. 
  • Time course and significance of changes in hepatic fructose-2,6-bisphosphate levels during refeeding of fasted rats. 
  • To condition or not condition? Analysing 'change' in longitudinal randomised controlled trials. 
  • Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. 
  • Treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin improves fasting islet-cell function in subjects with type 2 diabetes. 
  • Triglyceride Induced Metabolic Inflammation: Potential Connection of Insulin Resistance and Recurrent Pregnancy Loss. 
  • Urinary cadmium, impaired fasting glucose, and diabetes in the NHANES III. 
  • Validation of the Sleep Regularity Index in Older Adults and Associations with Cardiometabolic Risk. 
  • Weight reduction diets and health promotion. 
  • Weight-based teasing in youth: Associations with metabolic and inflammatory markers. 
  • Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. 
  • [Relaxation spectrometric studies of fast reactions of ATP in aqueous solution]. 
  • β-Cell Function Over Time in Adolescents With New Type 2 Diabetes and Obese Adolescents Without Diabetes. 
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  Keywords of People

  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Yancy Jr., William Samuel, Professor of Medicine, Medicine, General Internal Medicine