Fatty Acids

• 

  Subject Areas on Research

  • 4-Hydroxy-2(E)-nonenal (HNE) catabolism and formation of HNE adducts are modulated by β oxidation of fatty acids in the isolated rat heart. 
  • A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia. 
  • A Novel Mechanism for Th17 Inflammation in Human Type 2 Diabetes Mellitus. 
  • A Planar Culture Model of Human Absorptive Enterocytes Reveals Metformin Increases Fatty Acid Oxidation and Export. 
  • A bioorthogonal chemical reporter for fatty acid synthase-dependent protein acylation. 
  • A generic emergency protocol for patients with inborn errors of metabolism causing fasting intolerance: A retrospective, single-center study and the generation of www.emergencyprotocol.net. 
  • A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels. 
  • A murine model for short-chain acyl-CoA dehydrogenase deficiency. 
  • A new dietary therapy for adrenoleukodystrophy: biochemical and preliminary clinical results in 36 patients. 
  • A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report. 
  • A physicochemical study of fat absorption in rats. Limitation of methods in vitro. 
  • A preliminary metabolomic analysis of older adults with and without depression. 
  • A synthetic lecithin containing branched-chain fatty acids: physical properties and membrane studies. 
  • A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae. 
  • AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. 
  • Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. 
  • Abnormal fatty acid metabolism in spinal muscular atrophy may predispose to perioperative risks. 
  • Accurate fatty acid composition estimation of adipose tissue in the abdomen based on bipolar multi-echo MRI. 
  • Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat. 
  • Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency. 
  • Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders. 
  • Adaptation to fat markedly increases pancreatic secretory response to intraduodenal fat in rats. 
  • Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. 
  • Adrenoleukodystrophy associated with vitiligo and ulcerative colitis. 
  • Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features. 
  • Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance. 
  • Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy. 
  • An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents. 
  • Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study. 
  • Animal models of steatohepatitis. 
  • Animal models of steatosis. 
  • Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations. 
  • Antihyperlipidemic activity of amine cyanoboranes, amine carboxyboranes, and related compounds. 
  • Apolipoprotein E4 exaggerates diabetic dyslipidemia and atherosclerosis in mice lacking the LDL receptor. 
  • Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease. 
  • Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac catheterization cohort. 
  • Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis. 
  • Bacterial lipids: metabolism and membrane homeostasis. 
  • Bartonella vinsonii subsp. berkhoffii subsp. nov., isolated from dogs; Bartonella vinsonii subsp. vinsonii; and emended description of Bartonella vinsonii. 
  • Bed rest worsens impairments in fat and glucose metabolism in older, overweight adults. 
  • Benefits of Bempedoic Acid - Clearer Now. 
  • Biochemical changes in rat testis during postnatal maturation. 
  • Blunted fat oxidation upon submaximal exercise is partially compensated by enhanced glucose metabolism in children, adolescents, and young adults with Barth syndrome. 
  • Brain Arachidonic Acid Incorporation and Turnover are not Altered in the Flinders Sensitive Line Rat Model of Human Depression. 
  • Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight. 
  • Branched chain amino acid metabolic reprogramming in heart failure. 
  • CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin. 
  • Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence. 
  • Carnitine revisited: potential use as adjunctive treatment in diabetes. 
  • Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet. 
  • Changes in lipid profiles of liver microsomes of rats following intratracheal administration of DDT or endosulfan. 
  • Changes in lipid values and lipoprotein patterns of serum samples contaminated with bacteria. 
  • Characterization of new gangliosides of the lactotetraose series in murine xenografts of a human glioma cell line. 
  • Cholesterol controversy--where do we go from here? 'Toward healthful diets' reevaluated. 
  • Cholesteryl esters in flue-cured tobacco. 
  • Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism. 
  • Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder. 
  • Comparison of proximate composition and fatty acid and cholesterol content of lean and typical commercial pork. 
  • Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis. 
  • Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis: ANAPLEROSIS FROM DODECANEDIOATE. 
  • Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues. 
  • Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism. 
  • Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype. 
  • Cytosolic delivery of macromolecules: I. Synthesis and characterization of pH-sensitive acyloxyalkylimidazoles. 
  • Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content. 
  • De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics. 
  • Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis. 
  • Dengue virus-induced autophagy regulates lipid metabolism. 
  • Diabetes: The good in fat. 
  • Diet and neurocognition: review of evidence and methodological considerations. 
  • Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling. 
  • Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. 
  • Dietary fish oil. Influence on lesion regression in the porcine model of atherosclerosis. 
  • Differences in the metabolic response to exogenous homocysteine in juvenile and adult rabbits. 
  • Differential effects of modulation of docosahexaenoic acid content during development in specific regions of rat brain. 
  • Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. 
  • Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion. 
  • Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. 
  • Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3. 
  • Distinct patterns of fat metabolism in skeletal muscle of normal-weight, overweight, and obese humans. 
  • Distinct roles of specific fatty acids in cellular processes: implications for interpreting and reporting experiments. 
  • Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. 
  • Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults. 
  • Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma. 
  • Effect of actinomycin D on serum betalipoproteins of partially hepatectomized dogs. III - Fatty acid distribution. 
  • Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women. 
  • Effect of dietary fat saturation and cholesterol on low density lipoprotein degradation by mononuclear cells of Cebus monkeys. 
  • Effect of fatty acids on insulin release: role of chain length and degree of unsaturation. 
  • Effect of whole body gamma irradiation on fatty acid composition of liver lipids of female rats and radioprotection by cystamine. 
  • Effect-Directed Analysis of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) Ligands in Indoor Dust. 
  • Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism. 
  • Effects of fatty acid composition on the sensitivity of membrane functions to ethanol in Escherichia coli. 
  • Eicosanoids in corals and crustaceans: primary metabolites that function as allelochemicals and pheromones. 
  • Elastin-Like Polypeptides for Biomedical Applications. 
  • Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage. 
  • Elevated metabolites of acetaminophen in cord blood of children with obesity. 
  • Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. 
  • Endocarditis in a dog due to infection with a novel Bartonella subspecies. 
  • Energetics and metabolism in the failing heart: important but poorly understood. 
  • Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. 
  • Enhancement of endocrine pancreatic secretions by essential fatty acids. 
  • Evidence for indirect dietary regulation of cholecystokinin release in rats. 
  • Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis. 
  • Fatty acid composition of wild anthropoid primate milks. 
  • Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. 
  • Fatty acid metabolites in rapidly proliferating breast cancer. 
  • Fatty acid oxidation abnormalities in childhood-onset spinal muscular atrophy: primary or secondary defect(s)? 
  • Fatty acid oxidation and insulin action: when less is more. 
  • Fatty acid synthase: elementary steps in catalysis and regulation. 
  • Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal target. 
  • Fatty acid transport protein 2 reprograms neutrophils in cancer. 
  • Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice. 
  • Fenofibrate rapidly decreases hepatic lipid and glycogen storage in neonatal mice with glycogen storage disease type Ia. 
  • From the editor: Humans are animals and therefore make saturated fat. 
  • G proteins. Visual differences. 
  • G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency. 
  • Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse. 
  • Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation. 
  • Growth inhibitory effects of aromatic fatty acids on ovarian tumor cell lines. 
  • Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons. 
  • High heritability of metabolomic profiles in families burdened with premature cardiovascular disease. 
  • Honest olfactory ornamentation in a female-dominant primate. 
  • Human syngeneic intestinal transplantation: evaluation of enterocyte viability with serum levels of intestinal fatty acid binding protein. 
  • Hypervitaminosis A and tissue fatty acids. 
  • Identification and localization of the fatty acid modification in ghrelin by electron capture dissociation. 
  • Identification of N-acylphosphatidylserine molecules in eukaryotic cells. 
  • Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates. 
  • Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus. 
  • Images of divalent cations in unstained symmetric and asymmetric lipid bilayers. 
  • Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion. 
  • Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure. 
  • Incorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus. 
  • Incorporation of palmitate-1-14C into liver lipids of rats fed millet (Sorghum vulgarie) at different protein levels. 
  • Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency. 
  • Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation. 
  • Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy. 
  • Increasing atmospheric CO2 reduces metabolic and physiological differences between isoprene- and non-isoprene-emitting poplars. 
  • Inhibition of GABA-gated chloride channel function by arachidonic acid. 
  • Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins. 
  • Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. 
  • Interfacial phase transition of an environmentally responsive elastin biopolymer adsorbed on functionalized gold nanoparticles studied by colloidal surface plasmon resonance. 
  • Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver. 
  • Is bacterial fatty acid synthesis a valid target for antibacterial drug discovery? 
  • Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis. 
  • Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites. 
  • Isotopomer enrichment assay for very short chain fatty acids and its metabolic applications. 
  • L-glutamine supplementation of a high fat diet reduces body weight and attenuates hyperglycemia and hyperinsulinemia in C57BL/6J mice. 
  • Lack of utility of intestinal fatty acid binding protein levels in predicting intestinal allograft rejection. 
  • Leptin directly alters lipid partitioning in skeletal muscle. 
  • Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice. 
  • Lipid bilayer ultrastructure. Electron density profiles and chain tilt angles as determined by X-ray diffraction. 
  • Lipid environment of acetylcholine receptor from Torpedo californica. 
  • Lipid modifications of G proteins. 
  • Lipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells: effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpression. 
  • Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression. 
  • Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins. 
  • Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies. 
  • Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. 
  • Long-chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation. 
  • Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells. 
  • MRS measured fatty acid composition of periprostatic adipose tissue correlates with pathological measures of prostate cancer aggressiveness. 
  • Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi. 
  • Marine omega-3 fatty acids and cardiac death. 
  • Maternal Exercise and Paternal Exercise Induce Distinct Metabolite Signatures in Offspring Tissues. 
  • Measurement of fatty acid oxidation rates in animal tissues and cell lines. 
  • Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus. 
  • Metabolic Anthropology: Selection Pressure Shapes Fatty Acid Metabolism in Greenlandic Inuit Populations. 
  • Metabolic Reprogramming and Potential Therapeutic Targets in Lymphoma. 
  • Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors. 
  • Metabolism and vascular fatty acid transport. 
  • Metabolomic Approaches Reveal the Role of CAR in Energy Metabolism. 
  • Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure. 
  • Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure With Reduced Ejection Fraction: DEFINE-HF. 
  • Metabolomic Signature as a Predictor of Liver Disease Events in Patients With HIV/HCV Coinfection. 
  • Metabolomic analysis reveals altered skeletal muscle amino acid and fatty acid handling in obese humans. 
  • Metabolomic profiling of sphingolipids in human glioma cell lines by liquid chromatography tandem mass spectrometry. 
  • Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis. 
  • Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. 
  • Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function. 
  • Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish. 
  • Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. 
  • Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. 
  • Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy. 
  • Multi-omic profiles of hepatic metabolism in TPN-fed preterm pigs administered new generation lipid emulsions. 
  • Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. 
  • Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis. 
  • Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. 
  • N-Acylated Derivatives of Sulfamethoxazole Block Chlamydia Fatty Acid Synthesis and Interact with FabF. 
  • NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding. 
  • Near-roadway air pollution exposure and altered fatty acid oxidation among adolescents and young adults - The interplay with obesity. 
  • Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress. 
  • Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation. 
  • Nonpharmacologic Treatments for Attention-Deficit/Hyperactivity Disorder: A Systematic Review. 
  • Novel metabolomics markers are associated with pre-clinical decline in hand grip strength in community-dwelling older adults. 
  • Nutritional support in critically ill patients. 
  • Obesity, Immunity, and Cancer. 
  • Organ protective mechanisms common to extremes of physiology: a window through hibernation biology. 
  • Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits. 
  • Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells. 
  • Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. 
  • Overview of clinical perspectives and mechanisms of obesity. 
  • Oxygen flux analysis to understand the biological function of sirtuins. 
  • PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. 
  • PPAR alpha ligand protects during cisplatin-induced acute renal failure by preventing inhibition of renal FAO and PDC activity. 
  • Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. 
  • Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization. 
  • Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile. 
  • Pathogenesis of hepatic steatosis in the parenterally fed rat. 
  • Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. 
  • Peripheral blood metabolite profiles associated with new onset atrial fibrillation. 
  • Peripheral metabolic actions of leptin. 
  • Peritumoral expression of adipokines and fatty acids in breast cancer. 
  • Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals. 
  • Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252. 
  • Phosphoinositide Profile of the Mouse Retina. 
  • Physical properties of cholesteryl esters. 
  • Placental transport of free palmitic and linoleic acids in the guinea pig. 
  • Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men. 
  • Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears. 
  • Preliminary observations on abnormalities of membrane structure and function in essential hypertension. 
  • Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances and the risk of hypertensive disorders of pregnancy. 
  • Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. 
  • Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine. 
  • Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. 
  • Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults. 
  • Proteomic analysis of an unculturable bacterial endosymbiont (Blochmannia) reveals high abundance of chaperonins and biosynthetic enzymes. 
  • Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation. 
  • Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles. 
  • RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure. 
  • Radioprotection of lipogenesis from glucose (U-14C) and activities of pyridine nucleotide dehydrogenases in liver of gamma-irradiated female rats by cystamine. 
  • Rapid degradation of Deepwater Horizon spilled oil by indigenous microbial communities in Louisiana saltmarsh sediments. 
  • Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease. 
  • Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs. 
  • Regulation of gamma-aminobutyric acid/barbiturate receptor-gated chloride ion flux in brain vesicles by phospholipase A2: possible role of oxygen radicals. 
  • Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. 
  • Remodelling of the Vibrio cholerae membrane by incorporation of exogenous fatty acids from host and aquatic environments. 
  • Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism. 
  • Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family. 
  • Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo. 
  • SERUM LIPIDS IN LEPROSY BY SILICIC ACID COLUMN CHROMATOGRAPHY. 
  • SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. 
  • SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. 
  • Sensing Mitochondrial Acetyl-CoA to Tune Respiration. 
  • Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism. 
  • Serum fatty acids and incidence of ischemic stroke among postmenopausal women. 
  • Short chain fatty acids increase prolactin and growth hormone production and alter cell morphology in the GH3 strain of rat pituitary cells. 
  • Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells. 
  • Short-chain acyl-coenzyme A dehydrogenase deficiency in mice. 
  • Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. 
  • Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1 alpha: implications for metabolic disease. 
  • Specialized Pro-Resolving Lipid Mediators Regulate Ozone-Induced Pulmonary and Systemic Inflammation. 
  • Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression. 
  • Sphingolipid biosynthesis by rat liver cells: effects of serine, fatty acids and lipoproteins. 
  • Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin are associated with, but not required for, very low density lipoprotein secretion. 
  • Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice. 
  • Stimulation of long-chain fatty acid uptake by dipyridamole in isolated myocytes. 
  • Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. 
  • Structures of human Patched and its complex with native palmitoylated sonic hedgehog. 
  • Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood. 
  • Sutterella wadsworthensis gen. nov., sp. nov., bile-resistant microaerophilic Campylobacter gracilis-like clinical isolates. 
  • Systemic inflammatory response syndrome after human syngeneic intestinal transplantation: evidence for disruption of enterocyte barrier function. 
  • TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. 
  • The Failing Heart Relies on Ketone Bodies as a Fuel. 
  • The Roles of β-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana. 
  • The cellular lipids of Romboutsia. 
  • The engine driving the ship: metabolic steering of cell proliferation and death. 
  • The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist. 
  • The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy. 
  • The lipids of the erythrocyte in paroxysmal nocturnal hemoglobinuria. 
  • The role of phosphorylation/dephosphorylation of acetyl-CoA carboxylase in the regulation of mammalian fatty acid biosynthesis. 
  • The role of tandem mass spectrometry in the diagnosis of fatty acid oxidation disorders. 
  • The tandem mass spectrometry newborn screening experience in North Carolina: 1997-2005. 
  • Thyroid Hormone Decreases Hepatic Steatosis, Inflammation, and Fibrosis in a Dietary Mouse Model of Nonalcoholic Steatohepatitis. 
  • Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. 
  • Transcriptional Integration of Distinct Microbial and Nutritional Signals by the Small Intestinal Epithelium. 
  • Transgenic restoration of long-chain n-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high-fat-fed mice. 
  • Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice. 
  • Triheptanoin versus trioctanoin for long-chain fatty acid oxidation disorders: a double blinded, randomized controlled trial. 
  • Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. 
  • Urinary F2-isoprostanes and metabolic markers of fat oxidation. 
  • Vascular nutritional correlates of late-life depression. 
  • Very-late-onset adrenoleukodystrophy: possible precipitation of demyelination by cerebral contusion. 
  • Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation. 
  • Where people shop is not associated with the nutrient quality of packaged foods for any racial-ethnic group in the United States. 
  • X-ray diffraction analysis of isolated skin lipids: reconstitution of intercellular lipid domains. 
• 

  Keywords of People

  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology