Fentanyl

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  Subject Areas on Research

  • "It's probably going to save my life;" attitudes towards treatment among people incarcerated in the era of fentanyl. 
  • "One guy goes to jail, two people are ready to take his spot": Perspectives on drug-induced homicide laws among incarcerated individuals. 
  • A case of infant delirium in the neonatal intensive care unit. 
  • A comparison of remifentanil and fentanyl in patients undergoing surgery for intracranial mass lesions. 
  • A perioperative strategy for the placement of a thoracic epidural catheter in a pediatric patient on high-dose enoxaprin. 
  • A randomized double-blinded multicenter comparison of remifentanil versus fentanyl when combined with isoflurane/propofol for early extubation in coronary artery bypass graft surgery. 
  • Addition of epinephrine to epidural bupivacaine infusions following initiation of labor analgesia with epidural fentanyl. 
  • An evaluation of remifentanil-sevoflurane response surface models in patients emerging from anesthesia: model improvement using effect-site sevoflurane concentrations. 
  • Analgesia in the surgical intensive care unit. 
  • Anesthetic induction with fentanyl and intravenous lidocaine for coronary artery surgery. 
  • Anesthetic management of a patient having a carcinoid syndrome. 
  • Assessment of postoperative analgesia after application of ultrasound-guided regional anesthesia for surgery in a swine femoral fracture model. 
  • Bispectral analysis during cardiopulmonary bypass: the effect of hypothermia on the hypnotic state. 
  • Bolus Administration of Fentanyl and Midazolam for Colonoscopy Increases Endoscopy Unit Efficiency and Safety Compared With Titrated Sedation. 
  • Case series: Combined spinal epidural anesthesia for Cesarean delivery and ex utero intrapartum treatment procedure. 
  • Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism. 
  • Cognitive Impairment among People Who Use Heroin and Fentanyl: Findings from the Miami Adult Studies on HIV (MASH) Cohort. 
  • Comparison of remifentanil and fentanyl in patients undergoing craniotomy for supratentorial space-occupying lesions. 
  • Comparison of systemic oxygen delivery and uptake with NIR spectroscopy of brain during normovolemic hemodilution in the rabbit. 
  • Cost analysis of remifentanil and fentanyl for neurosurgical anesthesia. 
  • Current medication practice and tracheal intubation safety outcomes from a prospective multicenter observational cohort study. 
  • Determination of alfentanil and noralfentanil in human plasma by gas chromatography-mass spectrometry. 
  • Does functional ability in the postoperative period differ between remifentanil- and fentanyl-based anesthesia? 
  • Drug interactions: volatile anesthetics and opioids. 
  • ED 90 of Intrathecal Chloroprocaine With Fentanyl for Prophylactic Cervical Cerclage: A Sequential Allocation Biased-Coin Design. 
  • Effect of Intravenous Fentanyl on Ticagrelor Absorption and Platelet Inhibition Among Patients Undergoing Percutaneous Coronary Intervention: The PACIFY Randomized Clinical Trial (Platelet Aggregation With Ticagrelor Inhibition and Fentanyl). 
  • Effect of intrathecal fentanyl dose on the duration of labor analgesia. 
  • Effect of ritonavir-induced cytochrome P450 3A4 inhibition on plasma fentanyl concentrations during patient-controlled epidural labor analgesia: a pharmacokinetic simulation. 
  • Effects of isoflurane versus fentanyl-nitrous oxide anesthesia on long-term outcome from severe forebrain ischemia in the rat. 
  • Effects of isoflurane, ketamine, and fentanyl/N2O on concentrations of brain and plasma catecholamines during near-complete cerebral ischemia in the rat. 
  • Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia. 
  • Evaluation of flumazenil for reversing the effects of midazolam-induced conscious sedation or general anesthesia. 
  • Evidence-based oral transmucosal fentanyl citrate (OTFC) dosing guidelines. 
  • Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. 
  • Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions. 
  • Forty-eight hours of postoperative pain relief after total hip arthroplasty with a novel, extended-release epidural morphine formulation. 
  • G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal. 
  • Hemodynamics and emergence profile of remifentanil versus fentanyl prospectively compared in a large population of surgical patients. 
  • High-dose fentanyl does not adversely affect outcome from forebrain ischemia in the rat. 
  • Inadequate provision of postintubation anxiolysis and analgesia in the ED. 
  • Incidence of serotonin syndrome in patients treated with fentanyl on serotonergic agents. 
  • Influence of St. John's Wort on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics, and Clinical Effects: A Randomized Clinical Trial. 
  • Influence of age on the pharmacokinetics and pharmacodynamics of oral transmucosal fentanyl citrate. 
  • Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate. 
  • Inhaled fentanyl aerosol in healthy volunteers: pharmacokinetics and pharmacodynamics. 
  • Intracranial pressure response after pharmacologic treatment of intracranial hypertension. 
  • Intranasal Ketamine as an Adjunct to Fentanyl for the Prehospital Treatment of Acute Traumatic Pain: Design and Rationale of a Randomized Controlled Trial. 
  • Intranasal fentanyl improves time to analgesic delivery in sickle cell pain crises. 
  • Intranasal midazolam and fentanyl for procedural sedation and analgesia in infants in the neonatal intensive care unit. 
  • Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients. 
  • Intraoperative Methadone in Same-Day Ambulatory Surgery: A Randomized, Double-Blinded, Dose-Finding Pilot Study. 
  • Intraoperative awareness and hypertensive crisis during high-dose fentanyl-diazepam-oxygen anesthesia. 
  • Laparo-endoscopic single-site (LESS) cholecystectomy with epidural vs. general anesthesia. 
  • Local anesthetics and mode of delivery: bupivacaine versus ropivacaine versus levobupivacaine. 
  • Minimum effective dose of spinal ropivacaine with and without fentanyl for postpartum tubal ligation. 
  • Moderate sedation for MRI in young children with autism. 
  • More on epidural fentanyl analgesia. 
  • Neurocognitive performance under combined regimens of ketamine-dexmedetomidine and ketamine-fentanyl in healthy adults: A randomised trial. 
  • Onset and duration of neuromuscular blockade following high-dose vecuronium administration. 
  • Opioid sparing during endotracheal intubation using McCoy laryngoscope in neurosurgical patients: the comparison of haemodynamic changes with Macintosh blade in a randomized trial. 
  • Opioid-related respiratory and gastrointestinal adverse events in patients with acute postoperative pain: prevalence, predictors, and burden. 
  • Optimization of conscious sedation in plastic surgery. 
  • Oral transmucosal fentanyl citrate as an anaesthetic premedication when dosed to an opioid effect vs total opioid consumption. 
  • Outbreak of bacteremia due to Burkholderia contaminans linked to intravenous fentanyl from an institutional compounding pharmacy. 
  • Periischemic cerebral blood flow (CBF) does not explain beneficial effects of isoflurane on outcome from near-complete forebrain ischemia in rats. 
  • Pharmacokinetic model-driven infusion of fentanyl in children. 
  • Pharmacokinetic model-driven infusion of fentanyl: assessment of accuracy. 
  • Pharmacologic Treatment Reduces Pressure Times Time Dose and Relative Duration of Intracranial Hypertension. 
  • Postincarceration Fatal Overdoses After Implementing Medications for Addiction Treatment in a Statewide Correctional System. 
  • Postoperative nausea and vomiting. A retrospective analysis in patients undergoing elective craniotomy. 
  • Pro: midazolam is the sedative of choice to supplement narcotic anesthesia. 
  • Prospective randomized trial of normothermic versus hypothermic cardiopulmonary bypass on cognitive function after coronary artery bypass graft surgery. 
  • Quinidine as a probe for the role of p-glycoprotein in the intestinal absorption and clinical effects of fentanyl. 
  • Randomized double-blind trial of midazolam/placebo and midazolam/fentanyl for sedation and analgesia in lower-extremity angiography. 
  • Risk of fentanyl-involved overdose among those with past year incarceration: Findings from a recent outbreak in 2014 and 2015. 
  • Simultaneous assessment of drug interactions with low- and high-extraction opioids: application to parecoxib effects on the pharmacokinetics and pharmacodynamics of fentanyl and alfentanil. 
  • Single-dose extended-release epidural morphine for pain after hip arthroplasty. 
  • Single-dose extended-release epidural morphine for pain following hip arthroplasty. 
  • Small-dose intrathecal lidocaine versus ropivacaine for anorectal surgery in an ambulatory setting. 
  • Subarachnoid meperidine (Pethidine) causes significant nausea and vomiting during labor. The Duke Women's Anesthesia Research Group. 
  • The big short(age): perioperative and patient-reported outcomes during a fentanyl shortage at a tertiary care facility. 
  • The effect of intraoperative methadone during pediatric cardiac surgery on postoperative opioid requirements. 
  • The effects of anesthetics on stress responses to forebrain ischemia and reperfusion in the rat. 
  • The efficacy and resource utilization of remifentanil and fentanyl in fast-track coronary artery bypass graft surgery: a prospective randomized, double-blinded controlled, multi-center trial. 
  • The influence of lockout intervals and drug selection on patient-controlled analgesia following gynecological surgery. 
  • The opioid crisis and HIV in the USA: deadly synergies. 
  • The prevention of emesis in plastic surgery: a randomized, prospective study. 
  • The relative potency of oral transmucosal fentanyl citrate compared with intravenous morphine in the treatment of moderate to severe postoperative pain. 
  • The use of transcutaneous electrical nerve stimulation during the biliary lithotripsy procedure. 
  • The value of the P-value. 
  • Urban, individuals of color are impacted by fentanyl-contaminated heroin. 
  • Use of patient-controlled analgesia to compare the efficacy of epidural to intravenous fentanyl administration. 
  • Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity. 
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  Keywords of People

  • Esclamado, Ramon Mitra, Richard Hall Chaney, Sr. Distinguished Professor Emeritus of Otolaryngology, Head and Neck Surgery & Communication Sciences