Ferric Compounds

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  Subject Areas on Research

  • A 12-week, double-blind, placebo-controlled trial of ferric citrate for the treatment of iron deficiency anemia and reduction of serum phosphate in patients with CKD Stages 3-5. 
  • A Pilot Randomized Trial of Ferric Citrate Coordination Complex for the Treatment of Advanced CKD. 
  • A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia. 
  • A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation. 
  • A prospective randomized wait list control trial of intravenous iron sucrose in older adults with unexplained anemia and serum ferritin 20-200 ng/mL. 
  • Ab initio quantum mechanical/molecular mechanical simulation of electron transfer process: fractional electron approach. 
  • Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. 
  • Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers. 
  • Bordetella pertussis FbpA binds both unchelated iron and iron siderophore complexes. 
  • Cancer- and chemotherapy-induced anemia. 
  • Carrier-facilitated bulk liquid membrane transport of iron(III)-siderophore complexes utilizing first coordination sphere recognition. 
  • Characterization of Fe(III) sequestration by an analog of the cytotoxic siderophore brasilibactin A: implications for the iron transport mechanism in mycobacteria. 
  • Characterization of complexes between Escherichia coli sulfite reductase hemoprotein subunit and its substrates sulfite and nitrite. 
  • Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation. 
  • Chemical aspects of siderophore mediated iron transport. 
  • Clearance of depot vaccine SPIO-labeled antigen and substrate visualized using MRI. 
  • Comparative outcomes of predominant facility-level use of ferumoxytol versus other intravenous iron formulations in incident hemodialysis patients. 
  • Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor. 
  • Coordination chemistry of siderophores: thermodynamics and kinetics of iron chelation and release. 
  • Crystal and molecular structures of ionophore-siderophore host-guest supramolecular assemblies relevant to molecular recognition. 
  • Crystal structure of ferrioxamine B: a comparative analysis and implications for molecular recognition. 
  • DNA strand breaks following in vitro exposure to asbestos increase with surface-complexed [Fe3+]. 
  • DRIVE it home: making the case for prospective economic data collection in randomized clinical trials. 
  • Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging. 
  • Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology. 
  • Direct evaluation of electronic coupling mediated by hydrogen bonds: implications for biological electron transfer. 
  • Divalent metal transporter-1 decreases metal-related injury in the lung. 
  • Editorial: awareness and prevention of intravenous iron-induced hypophosphataemia. 
  • Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinical Trials. 
  • Effects of ferric carboxymaltose on markers of mineral and bone metabolism: A single-center prospective observational study of women with iron deficiency. 
  • Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women. 
  • Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917. 
  • Evidence for siroheme-Fe4S4 interaction in spinach ferredoxin-sulfite reductase. 
  • FGF23 at the crossroads of phosphate, iron economy and erythropoiesis. 
  • Factors that influence siderophoremediated iron bioavailability: catalysis of interligand iron (III) transfer from ferrioxamine B to EDTA by hydroxamic acids. 
  • Fe(III) coordination properties of a new saccharide-based exocyclic trihydroxamate analogue of ferrichrome. 
  • Fe(III) coordination properties of two new saccharide-based enterobactin analogues: methyl 2,3,4-tris-O-[N-[2,3-di(hydroxy)benzoyl-glycyl]-aminopropyl]-alpha-D-glucopyranoside and methyl 2,3,4-tris-O-[N-[2,3-di-(hydroxy)-benzoyl]-aminopropyl]-alpha-D-glucopyranoside. 
  • Fe3+ coordination and redox properties of a bacterial transferrin. 
  • Fe3O4 magnetic nanoparticles as peroxidase mimetics and their applications in H2O2 and glucose detection. 
  • Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury. 
  • Ferric carboxymaltose in patients with iron-deficiency anemia and impaired renal function: the REPAIR-IDA trial. 
  • Ferric citrate reduces fibroblast growth factor 23 levels and improves renal and cardiac function in a mouse model of chronic kidney disease. 
  • Ferromagnetic hyperthermia and iodine 125 brachytherapy in the treatment of choroidal melanoma in a rabbit model. 
  • Ferrous iron content of intravenous iron formulations. 
  • Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer. 
  • Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA. 
  • Graphite-coated magnetic nanoparticle microarray for few-cells enrichment and detection. 
  • How can a single second sphere amino acid substitution cause reduction midpoint potential changes of hundreds of millivolts? 
  • Hypophosphataemia after treatment of iron deficiency with intravenous ferric carboxymaltose or iron isomaltoside-a systematic review and meta-analysis. 
  • Hypothesis: is lung disease after silicate inhalation caused by oxidant generation? 
  • Importance of a nanoscience approach in the understanding of major aqueous contamination scenarios: case study from a recent coal ash spill. 
  • Improved Hemoglobin Response with Ferric Carboxymaltose in Patients with Gastrointestinal-Related Iron-Deficiency Anemia Versus Oral Iron. 
  • Improving sensitivity and specificity of capturing and detecting targeted cancer cells with anti-biofouling polymer coated magnetic iron oxide nanoparticles. 
  • Interaction of K7Fe3+P2W17O62H2 with supported bilayer lipid membranes on platinum electrode. 
  • Iron chelation properties of an extracellular siderophore exochelin MN. 
  • Iron chelation properties of an extracellular siderophore exochelin MS. 
  • Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study. 
  • Iron oxide/manganese oxide co-loaded hybrid nanogels as pH-responsive magnetic resonance contrast agents. 
  • Iron uptake and Nramp2/DMT1/DCT1 in human bronchial epithelial cells. 
  • Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport. 
  • Microbe-Encapsulated Silica Gel Biosorbents for Selective Extraction of Scandium from Coal Byproducts. 
  • Molecular MRI for sensitive and specific detection of lung metastases. 
  • Optimization of the lariat ether carboxylic acid host structure for ferrioxamine B: demonstration of a second coordination shell chelate effect. 
  • Oxidative iron species and ocean challenges: a perspective. 
  • Phagocyte-generated superoxide reduces Fe3+ to displace it from the surface of asbestos. 
  • Phenotyping heart failure patients for iron deficiency and use of intravenous iron therapy: data from the Swedish Heart Failure Registry. 
  • Radiation synovectomy with 165Dy-FHMA: lymph node uptake and radiation dosimetry calculations. 
  • Randomised clinical trial of ferric citrate hydrate on anaemia management in haemodialysis patients with hyperphosphataemia: ASTRIO study. 
  • Randomized Placebo-Controlled Trial of Ferric Carboxymaltose in Heart Failure With Iron Deficiency: Rationale and Design. 
  • Randomized evaluation of efficacy and safety of ferric carboxymaltose in patients with iron deficiency anaemia and impaired renal function (REPAIR-IDA): rationale and study design. 
  • Randomized trial of intravenous iron-induced hypophosphatemia. 
  • Redox potentials of Ti(IV) and Fe(III) complexes provide insights into titanium biodistribution mechanisms. 
  • Redox properties of human transferrin bound to its receptor. 
  • Risk Factors for and Effects of Persistent and Severe Hypophosphatemia Following Ferric Carboxymaltose. 
  • Role of citrate and phosphate anions in the mechanism of iron(III) sequestration by ferric binding protein: kinetic studies of the formation of the holoprotein of wild-type FbpA and its engineered mutants. 
  • Safety and efficacy of iron isomaltoside 1000/ferric derisomaltose versus iron sucrose in patients with chronic kidney disease: the FERWON-NEPHRO randomized, open-label, comparative trial. 
  • Safety and technique of ferumoxytol administration for MRI. 
  • Safety of Intravenous Iron in Hemodialysis: Longer-term Comparisons of Iron Sucrose Versus Sodium Ferric Gluconate Complex. 
  • Single-Step Assembly of Multimodal Imaging Nanocarriers: MRI and Long-Wavelength Fluorescence Imaging. 
  • Synovectomy of the rheumatoid knee using intra-articular injection of dysprosium-165-ferric hydroxide macroaggregates. 
  • Ternary complex formation facilitates a redox mechanism for iron release from a siderophore. 
  • The Phosphate Binder Ferric Citrate and Mineral Metabolism and Inflammatory Markers in Maintenance Dialysis Patients: Results From Prespecified Analyses of a Randomized Clinical Trial. 
  • The emerging role of ferumoxytol-enhanced MRI in the management of cerebrovascular lesions. 
  • The kinetics of dimethylhydroxypyridinone interactions with iron(iii) and the catalysis of iron(iii) ligand exchange reactions: implications for bacterial iron transport and combination chelation therapies. 
  • The stathmokinetic and morphological response of the hamster respiratory epithelium to intralaryngeal instillations of saline and ferric oxide in saline. 
  • Thermodynamics, kinetics, and mechanism of the stepwise dissociation and formation of Tris(L-lysinehydroxamato)iron(III) in aqueous acid. 
  • Transition metal-chelate complexes as relaxation modifiers in nuclear magnetic resonance. 
  • Treatment of Invasive Brain Tumors Using a Chain-like Nanoparticle. 
  • Treatment of rheumatoid synovitis of the knee with intraarticular injection of dysprosium 165-ferric hydroxide macroaggregates. 
  • Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline. 
  • Using alpha-helical coiled-coils to design nanostructured metalloporphyrin arrays. 
  • Video-assisted thoracoscopic transplantation of myoblasts into the heart. 
  • iDQC anisotropy map imaging for tumor tissue characterization in vivo. 
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  Keywords of People

  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering