Fertilization in Vitro

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  Subject Areas on Research

  • A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF. 
  • A comparative analysis of embryo implantation potential in patients with severe teratozoospermia undergoing in-vitro fertilization with a high insemination concentration or intracytoplasmic sperm injection. 
  • A comparison of methods for measuring socio-economic status by occupation or postal area. 
  • A conceptual framework for patient-centered fertility treatment. 
  • A prospective, randomized, double-blind study for the evaluation of assisted hatching in patients with advanced maternal age. 
  • Acute ureteral obstruction following transvaginal oocyte retrieval for IVF. 
  • Allergic reactions to penicillin during in vitro fertilization and intrauterine insemination. 
  • Alterations in luteal phase progesterone and estradiol production after leuprolide acetate therapy before ovarian stimulation for in vitro fertilization. 
  • An analysis of the obstetric outcome of 125 consecutive pregnancies conceived in vitro and resulting in 100 deliveries. 
  • An artificial fertilization method with the Japanese medaka: implications in early life stage bioassays and solvent toxicity. 
  • Analysis of ectopic pregnancies resulting from in-vitro fertilization and embryo transfer. 
  • Analysis of implantation in assisted reproduction through the use of serial human chorionic gonadotropin measurements. 
  • Are implantation and pregnancy outcome impaired in diethylstilbestrol-exposed women after in vitro fertilization and embryo transfer? 
  • Aspirin and reproductive outcomes. 
  • Association between donor gamete use and supernumerary embryo disposition decisions. 
  • Basal follicle-stimulating hormone level is a better predictor of in vitro fertilization performance than age. 
  • Beta-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization-embryo transfer patients. 
  • Celiac disease is not more prevalent in patients undergoing in vitro fertilization and does not affect reproductive outcomes with or without treatment: a large prospective cohort study. 
  • Cessation of gonadotropin-releasing hormone agonist therapy combined with high-dose gonadotropin stimulation yields favorable pregnancy results in low responders. 
  • Clinical pregnancy (CP) and live birth (LB) increase significantly with each additional fertilized oocyte up to nine, and CP and LB decline after that: an analysis of 15,803 first fresh in vitro fertilization cycles from the Society for Assisted Reproductive Technology registry. 
  • Clinical utility of antiphospholipid antibodies? A negative study with power! 
  • Clinical utility of antiphospholipid antibodies? A negative study with power! 
  • Combined impact of the number of pre-ovulatory oocytes and cryopreservation on IVF outcome. 
  • Comparison between laparoscopically and ultrasonographically guided transvaginal follicular aspiration methods in an in vitro fertilization program in the same patients using the same stimulation protocol. 
  • Conclusions about the effects on fertilization of time from aspiration to incubation and blood in the aspirate depend on the use of appropriate statistical techniques. 
  • Control of air quality in an assisted reproductive technology laboratory. 
  • Correlation of follicular diameter with oocyte recovery and maturity at the time of transvaginal follicular aspiration. 
  • Cortical granule exocytosis is triggered by different thresholds of calcium during fertilisation in sea urchin eggs. 
  • Cost-effectiveness of prenatal screening methods for congenital heart defects in pregnancies conceived by in-vitro fertilization. 
  • Cryopreservation of all prezygotes in patients at risk of severe hyperstimulation does not eliminate the syndrome, but the chances of pregnancy are excellent with subsequent frozen-thaw transfers. 
  • Cycle scheduling with oral contraceptives: Are we compromising rates for convenience? 
  • Defining recurrent implantation failure: a profusion of confusion or simply an illusion? 
  • Delayed fertilization during in vitro fertilization and embryo transfer cycles: analysis of causes and impact on overall results. 
  • Delaying the initiation of progesterone supplementation results in decreased pregnancy rates after in vitro fertilization: a randomized, prospective study. 
  • Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance. 
  • Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry. 
  • Do not increase the burden for poor responders. 
  • Donor oocytes are associated with preterm birth when compared to fresh autologous in vitro fertilization cycles in singleton pregnancies. 
  • Early follicular rise of serum progesterone concentration in response to a flare-up effect of gonadotrophin-releasing hormone agonist impairs follicular recruitment for in-vitro fertilization. 
  • Effect of hydrosalpinx on IVF outcome--mechanism? 
  • Effectiveness of assisted reproductive technology (ART). 
  • Effects of myomas or prior myomectomy on in vitro fertilization (IVF) performance. 
  • Effects of the severity of tubo-ovarian disease and previous tubal surgery on the results of in vitro fertilization and embryo transfer. 
  • Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation. 
  • Embryo implantation in in vitro fertilization and intracytoplasmic sperm injection: impact of cleavage status, morphology grade, and number of embryos transferred. 
  • Embryo quality and pregnancy rates in patients attempting pregnancy through in vitro fertilization. 
  • Embryo transfer to the uterus or the fallopian tube after in vitro fertilization yields similar results. 
  • Endometriosis, in vitro fertilisation and the risk of gynaecological malignancies, including ovarian and breast cancer. 
  • Estrogen and progesterone production by granulosa cell monolayers derived from in vitro fertilization procedures: lack of evidence for modulation by androgen. 
  • Evidence-based treatments for couples with unexplained infertility: a guideline. 
  • Experience with diethylstilbestrol-exposed infertile women in a program of in vitro fertilization. 
  • Experience with subzonal insemination (SUZI) and intracytoplasmic sperm injection (ICSI) on unfertilized aged human oocytes. 
  • Exploring reproductive associations of serum polybrominated diphenyl ether and hydroxylated brominated diphenyl ether concentrations among women undergoing in vitro fertilization. 
  • Fertilising ability of testicular spermatozoa. 
  • Fertility patients' views about frozen embryo disposition: results of a multi-institutional U.S. survey. 
  • Fertilization and in vitro development of cryopreserved human prophase I oocytes. 
  • Fewer medications for in vitro fertilization can be better: thinking outside the box. 
  • Follicle-stimulating hormone levels on cycle day 3 are predictive of in vitro fertilization outcome. 
  • Follicular atresia associated with concurrent initiation of gonadotropin-releasing hormone agonist and follicle-stimulating hormone for oocyte recruitment. 
  • Follicular development, acquisition of mature oocytes, and pregnancy after 2 weeks of leuprolide acetate administration during the midluteal phase. 
  • Freezing of all embryos in in vitro fertilization is beneficial in high responders, but not intermediate and low responders: an analysis of 82,935 cycles from the Society for Assisted Reproductive Technology registry. 
  • Freezing techniques and results. 
  • Gonadotropin stimulation for in vitro fertilization and embryo transfer in insulin-dependent diabetics: follicular response, oocyte quality, embryo development, and follicular environment. 
  • Gonadotropin stimulation protocols in the Norfolk IVF program--1988. 
  • Heterotopic cervical pregnancy treated with transvaginal ultrasound-guided aspiration resulting in cervical site varices within the myometrium. 
  • High Peak Estradiol Predicts Higher Miscarriage and Lower Live Birth Rates in High Responders Triggered with a GnRH Agonist in IVF/ICSI Cycles. 
  • High doses of gonadotropins have no detrimental effect on in vitro fertilization outcome in normal responders. 
  • High relative deoxyribonucleic acid content of trophectoderm biopsy adversely affects pregnancy outcomes. 
  • High-dose follicle-stimulating hormone (FSH) ovarian stimulation in low-responder patients for in vitro fertilization. 
  • High-dose follicle-stimulating hormone stimulation at the onset of the menstrual cycle does not improve the in vitro fertilization outcome in low-responder patients. 
  • How compliant are in vitro fertilization member clinics in following embryo transfer guidelines? An analysis of 59,689 fresh first in vitro fertilization autologous cycles from 2011 to 2012. 
  • Human embryos derived from in vitro and in vivo matured oocytes: analysis for chromosomal abnormalities and nuclear morphology. 
  • Human granulosa-luteal and cumulus cells express transforming growth factors-beta type 1 and type 2 mRNA. 
  • IVF births and pregnancies: an exploration of two methods of assessment using life-table analysis. 
  • Impact of fertilization history and semen parameters on ICSI outcome. 
  • Impact of leuprolide acetate on the response to follicular stimulation for in vitro fertilization in patients with normal basal gonadotropin levels. 
  • Implantation and pregnancy rates in relation to oestradiol and progesterone profiles in cycles with and without the use of gonadotrophin-releasing hormone agonist suppression. 
  • Implantation potential of each pre-embryo in multiple pregnancies obtained by in vitro fertilization seems to be different. 
  • Improved oocyte quality is obtained with follicle stimulating hormone alone than with follicle stimulating hormone/human menopausal gonadotrophin combination. 
  • In Vitro Activation: A Possible New Frontier for Treatment of Primary Ovarian Insufficiency. 
  • In vitro fertilization and acupuncture: clinical efficacy and mechanistic basis. 
  • In vitro fertilization and embryo transfer (IVF-ET) comes to the upstate. 
  • In vitro fertilization and embryo transfer (IVF/ET): an established and successful therapy for endometriosis. 
  • In vitro fertilization: effective alternative to surgery for distal tubal occlusion. 
  • In-vitro fertilization and embryo transfer in patients with endometriosis: impact of a gonadotrophin releasing hormone agonist. 
  • Infertility patients in general and those with celiac disease may be able to breathe a sigh of relief. 
  • Intercycle variability of day 3 follicle-stimulating hormone levels and its effect on stimulation quality in in vitro fertilization. 
  • Interpretation of noninvasive prenatal testing results following in vitro fertilization and preimplantation genetic testing for aneuploidy. 
  • Intracytoplasmic sperm injection: achievement of high pregnancy rates in couples with severe male factor infertility is dependent primarily upon female and not male factors. 
  • Is the rate of congenital heart defects detected by fetal echocardiography among pregnancies conceived by in vitro fertilization really increased?: a case-historical control study. 
  • Is the timing of implantation affected by zona pellucida micromanipulation? 
  • Late intracytoplasmic sperm injection in unexpected failed fertilization in vitro: diagnostic or therapeutic? 
  • Low-dose glucocorticoids after in vitro fertilization and embryo transfer have no significant effect on pregnancy rate. 
  • Luteal phase serum estradiol and progesterone in in vitro fertilization. 
  • Luteal supplementation in in vitro fertilization: more questions than answers. 
  • Luteal support with both estradiol and progesterone after clomiphene citrate stimulation for in vitro fertilization. 
  • Maternal adjustment, parenting and child behaviour in families of school-aged twins conceived after IVF and ovulation induction. 
  • Medical study: aspiring parents, genotypes and phenotypes: the unexamined myth of the perfect baby. 
  • Mild/minimal stimulation for in vitro fertilization: an old idea that needs to be revisited. 
  • Minimal ovarian hyperstimulation for in vitro fertilization using sequential clomiphene citrate and gonadotropin with or without the addition of a gonadotropin-releasing hormone antagonist. 
  • Monitoring gonadotropin-stimulated cycles for in vitro fertilization and embryo transfer. 
  • Multidimensional Psychological Stress During Pregnancies in Women Who Conceived via In Vitro Fertilization. 
  • Non-functional ovarian cysts do not affect ipsilateral or contralateral ovarian performance during in-vitro fertilization. 
  • Nurses are an asset to an in vitro fertilization program, and more so if they are continually educated. 
  • Obstetrician-gynecologists' beliefs about assisted reproductive technologies. 
  • On reporting pregnancies by assisted reproductive technology. 
  • Oocyte donation. The Norfolk Program. 
  • Oocyte number as a predictor for ovarian hyperstimulation syndrome and live birth: an analysis of 256,381 in vitro fertilization cycles. 
  • Optimal stimulation protocols for in vitro fertilization. 
  • Outcome of triplet and quadruplet pregnancies resulting from in vitro fertilization. 
  • Outcome of twin, triplet, and quadruplet in vitro fertilization pregnancies: the Norfolk experience. 
  • Outcomes after assisted reproductive technology in women with cancer: a systematic review and meta-analysis. 
  • Outcomes of donor oocyte cycles in assisted reproduction. 
  • Ovarian hyperstimulation causing ureteral obstruction in a pregnant woman. 
  • Ovarian stimulation for in vitro fertilization in low-responder patients using pulsatile intravenous follicle stimulating hormone. 
  • Ovarian stimulation for in vitro fertilization using pure follicle-stimulating hormone with and without gonadotropin-releasing hormone agonist in high-responder patients. 
  • Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization. 
  • Penetration of human spermatozoa into the human zona pellucida and the zona-free hamster egg: a study of fertile donors and infertile patients. 
  • Percutaneous epididymal sperm aspiration and intracytoplasmic sperm injection in the management of infertility due to obstructive azoospermia. 
  • Performance of cryopreserved pre-embryos obtained in in vitro fertilization cycles with or without a gonadotropin-releasing hormone agonist. 
  • Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial. 
  • Pre-implantation genetic testing alters the sex ratio: an analysis of 91,805 embryo transfer cycles. 
  • Preclinical abortions: incidence and significance in the Norfolk in vitro fertilization program. 
  • Preconception Evaluation Before In Vitro Fertilization. 
  • Prediction of fertilization in vitro with human gametes: is there a litmus test? 
  • Predictive value of pregnancy during original in vitro fertilization cycle on implantation and pregnancy in subsequent cryothaw cycles. 
  • Pregnancy following transfer of ooplasm from cryopreserved-thawed donor oocytes into recipient oocytes. 
  • Pregnancy outcomes decline in recipients over age 44: an analysis of 27,959 fresh donor oocyte in vitro fertilization cycles from the Society for Assisted Reproductive Technology. 
  • Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the 2008-2010 Society for Assisted Reproductive Technology registry. 
  • Pregnancy outcomes decline with increasing recipient body mass index: an analysis of 22,317 fresh donor/recipient cycles from the 2008-2010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System registry. 
  • Pregnancy rates in donor oocyte cycles compared to similar autologous in vitro fertilization cycles: an analysis of 26,457 fresh cycles from the Society for Assisted Reproductive Technology. 
  • Preterm Delivery and Low Birth Weight Among Neonates Conceived With Intracytoplasmic Sperm Injection Compared With Conventional In Vitro Fertilization. 
  • Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse. 
  • Progesterone levels on the day of human chorionic gonadotropin administration in cycles with gonadotropin-releasing hormone agonist suppression are not predictive of pregnancy outcome. 
  • Progesterone levels on the day of human chorionic gonadotropin do not predict pregnancy outcome from the transfer of fresh or cryopreserved embryos from the same cohort. 
  • Racial and ethnic disparities among donor oocyte banks in the United States. 
  • Rectus sheath hematoma after transvaginal follicle aspiration: a rare complication of in vitro fertilization. 
  • Recurrent failure of in vitro fertilization: role of the hemizona assay in the sequential diagnosis of specific sperm-oocyte defects. 
  • Reduced pregnancy outcome in patients with unilateral or bilateral hydrosalpinx after in vitro fertilization. 
  • Relationship between human chorionic gonadotropin serum levels and the risk of ovarian hyperstimulation syndrome. 
  • Repeated In Vitro Fertilization Cycles for Infertility. 
  • Results of in vitro fertilization attempts in patients with one or two ovaries. 
  • Results of in vitro fertilization attempts in women 40 years of age and older: the Norfolk experience. 
  • SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts. 
  • Salpingectomy improves the pregnancy rate in in-vitro fertilization patients with hydrosalpinx. 
  • Semen quality: is there a paternal effect on pregnancy outcome in in-vitro fertilization/intracytoplasmic sperm injection? 
  • Should we stop offering endometrial scratching prior to in vitro fertilization? 
  • Sibling rivalry? Higher birthweight after frozen embryo transfer compared with fresh sibling embryo transfers. 
  • Significance of basal follicle-stimulating hormone levels in women with one ovary in a program of in vitro fertilization. 
  • Significantly enhanced pregnancy rates per cycle through cryopreservation and thaw of pronuclear stage oocytes. 
  • Single- and double-lumen needles for oocyte harvesting. 
  • Society for Maternal-Fetal Medicine Consult Series #60: Management of pregnancies resulting from in vitro fertilization. 
  • Sonographic appearance of the endometrium: the predictive value for the outcome of in-vitro fertilization in stimulated cycles. 
  • Sperm morphology as diagnosed by strict criteria: probing the impact of teratozoospermia on fertilization rate and pregnancy outcome in a large in vitro fertilization population. 
  • Stage-specific toxicity of cypermethrin to medaka (Oryzias latipes) eggs and embryos using a refined methodology for an in vitro fertilization bioassay. 
  • State Insurance Mandates and Multiple Birth Rates After In Vitro Fertilization. 
  • Stimulation protocols for patients with "atypical response". 
  • Stress and Anxiety in Couples Who Conceive via In Vitro Fertilization Compared With Those Who Conceive Spontaneously. 
  • Successful fertilization and pregnancy outcome in in-vitro fertilization using cryopreserved/thawed spermatozoa from patients with malignant diseases. 
  • Successful prophylactic regimens for transvaginal oocyte retrieval in women with bleeding diatheses. 
  • Superovulation with intrauterine insemination in the treatment of infertility: a possible alternative to gamete intrafallopian transfer and in vitro fertilization. 
  • Suppression and flare regimens of gonadotropin-releasing hormone agonist. Use in women with different basal gonadotropin values in an in vitro fertilization program. 
  • Survival of the cornual pregnancy in a heterotopic gestation after in vitro fertilization and embryo transfer. 
  • T-helper 2 and 3 type immunity to trophoblast in successful in vitro fertilization-embryo transfer. 
  • The Appraisal of Body Content (ABC) trial: Increased male or female adiposity does not significantly impact in vitro fertilization laboratory or clinical outcomes. 
  • The Risk of Congenital Anomalies by Fertility Treatment Modality. 
  • The appraisal of body content (ABC) trial: obesity does not significantly impact gamete production in infertile men and women. 
  • The combination of follicle-stimulating hormone and human menopausal gonadotropin for the induction of multiple follicular maturation for in vitro fertilization. 
  • The expression level of C19MC miRNAs in early pregnancy and in response to viral infection. 
  • The gonadotropin-releasing hormone agonist stimulation test--a sensitive predictor of performance in the flare-up in vitro fertilization cycle. 
  • The impact of contemporary preimplantation genetic screening and diagnosis on the detection of aneuploidy and inherited genetic diseases. 
  • The incidence of multiple gestations after in vitro fertilization is dependent on the number of embryos transferred and maternal age. 
  • The incidence of transient hyperprolactinemia in gonadotropin-stimulated cycles for in vitro fertilization and its effect on pregnancy outcome. 
  • The indications for in vitro fertilization. 
  • The outcome of clinical pregnancies following intracytoplasmic sperm injection is not affected by semen quality. 
  • The perimenopausal patient in in vitro fertilization: the use of gonadotropin-releasing hormone. 
  • The prevalence of human immunodeficiency virus in patients and their spouses entering a large in vitro fertilization program. 
  • The significance of hydrosalpinx in in vitro fertilization. 
  • The value of basal and/or stimulated serum gonadotropin levels in prediction of stimulation response and in vitro fertilization outcome. 
  • The value of in vitro fertilization for the treatment of unexplained infertility. 
  • Three-dimensional ultrasound diagnosis of adenomyosis is not associated with adverse pregnancy outcome following single thawed euploid blastocyst transfer: prospective cohort study. 
  • Timing of oocyte retrieval in cycles with a spontaneous luteinizing hormone surge in a large in vitro fertilization program. 
  • Too much time? Time use and fertility-specific quality of life among men and women seeking specialty care for infertility. 
  • Total follicle stimulating hormone dose is negatively correlated with live births in a donor/recipient model with fresh transfer: an analysis of 8,627 cycles from the Society for Assisted Reproductive Technology Registry. 
  • Total quality improvement in the IVF laboratory: choosing indicators of quality. 
  • Toward a more meaningful in vitro fertilization success rate. 
  • Treatment of low responders. 
  • Treatment-independent, treatment-associated, and pregnancies after additional therapy in a program of in vitro fertilization and embryo transfer. 
  • Ultrasonographic appearance of the endometrium in natural and stimulated in-vitro fertilization cycles and its correlation with outcome. 
  • Understanding endometriosis is the key to successful therapeutic management. 
  • Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization. 
  • Use and outcomes of intracytoplasmic sperm injection for non-male factor infertility. 
  • Use of fertility preservation services in female reproductive-aged cancer patients. 
  • Use of gonadotrophin-releasing hormone agonists in controlled ovarian hyperstimulation for in vitro fertilization. 
  • Use of hMG and/or FSH for multiple follicle development. 
  • Using Society for Assisted Reproductive Technology data to track pregnancy outcomes in older recipients: is it justifiable? 
  • Utility of fluoroimmunoassay in detecting luteinizing hormone surges in spontaneous and human menopausal gonadotropin-stimulated menstrual cycles. 
  • Validity and cost-effectiveness of antisperm antibody testing before in vitro fertilization. 
  • Value of suppression with a gonadotropin-releasing hormone agonist prior to gonadotropin stimulation for in vitro fertilization. 
  • Willingness of Women with Endometriosis Planning to Undergo IVF to Participate in a Randomized Clinical Trial and the Effects of the COVID-19 Pandemic on Potential Participation. 
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  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Weber, Jeremy, Biostatistician III, Biostatistics & Bioinformatics