Fibroblasts

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  Subject Areas on Research

  • 3-Hydroxyisovalerylcarnitine in 3-methylcrotonyl-CoA carboxylase deficiency. 
  • 5' UTR m(6)A Promotes Cap-Independent Translation. 
  • 5' flanking DNA sequences direct cell-specific expression of rat tyrosine hydroxylase. 
  • A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. 
  • A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells. 
  • A beta-blocker, propranolol, decreases the efficacy from enzyme replacement therapy in Pompe disease. 
  • A bioenergetic profile of non-transformed fibroblasts uncovers a link between death-resistance and enhanced spare respiratory capacity. 
  • A common duplication in the lysyl hydroxylase gene of patients with Ehlers Danlos syndrome type VI results in preferential stimulation of lysyl hydroxylase activity and mRNA by hydralazine. 
  • A comparative histologic study of rapid three-dimensional zygomatic suture expansion osteogenesis. 
  • A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency. 
  • A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses. 
  • A galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes. 
  • A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. 
  • A mass spectrometry-based proteomic approach to study Marek's Disease Virus gene expression. 
  • A mathematical model for the receptor mediated cellular regulation of the low density lipoprotein metabolism. 
  • A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. 
  • A new generation organ culture arising from cross-talk between multiple primary human cell types. 
  • A new paradigm for corneal wound healing research: the white leghorn chicken (Gallus gallus domesticus). 
  • A new role for ATM: regulating mitochondrial function and mitophagy. 
  • A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network. 
  • A novel missense mutation in POMT1 modulates the severe congenital muscular dystrophy phenotype associated with POMT1 nonsense mutations. 
  • A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report. 
  • A patient with Ehlers-Danlos syndrome type VI is homozygous for a premature termination codon in exon 14 of the lysyl hydroxylase 1 gene. 
  • A proteomic approach for dissecting H-Ras signaling networks in NIH/3T3 mouse embryonic fibroblast cells. 
  • A proteomic approach for unraveling the oncogenic H-Ras protein networks in NIH/3T3 mouse embryonic fibroblast cells. 
  • A requirement for ankyrin binding to clathrin during coated pit budding. 
  • A role for the copper transporter Ctr1 in the synergistic interaction between hyperthermia and cisplatin treatment. 
  • A sensitive, specific radioisotope assay for L-glutamine-D-fructose-6-phosphate aminotransferase. 
  • A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. 
  • A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo. 
  • A unique role of the DNA fragmentation factor in maintaining genomic stability. 
  • AAV Gene Therapy for MPS1-associated Corneal Blindness. 
  • ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. 
  • ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming. 
  • ATM activation in normal human tissues and testicular cancer. 
  • ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. 
  • Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases. 
  • Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. 
  • Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling. 
  • Abnormal gene expression profiles in unaffected parents of patients with hereditary-type retinoblastoma. 
  • Abnormal oxidative stress responses in fibroblasts from preeclampsia infants. 
  • Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation. 
  • Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. 
  • Absence of three secreted proteins and presence of a 57-kDa protein related to irreversible arrest of cell growth. 
  • Accelerated rejection of skin grafts in recipients sensitized with extracted human histocompatibility antigens. 
  • Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks 
  • Acetylcholine promotes the proliferation and collagen gene expression of myofibroblastic hepatic stellate cells. 
  • Aclacinomycin A in the treatment of experimental proliferative vitreoretinopathy. Efficacy and toxicity in the rabbit eye. 
  • Acquisition of mitochondrial dysregulation and resistance to mitochondrial-mediated apoptosis after genotoxic insult in normal human fibroblasts: a possible model for early stage carcinogenesis. 
  • Acral myxoinflammatory fibroblastic sarcomas: MRI findings in four cases. 
  • Actions of thrombin in the interstitium. 
  • Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells. 
  • Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge to MEK1/ERK2 and activate the Elk1 transcription factor. 
  • Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117. 
  • Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency. 
  • Acute fatty liver of pregnancy, hemolysis, elevated liver enzymes, and low platelets syndrome, and long chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency. 
  • Acute histologic effects of extraesophageal reflux on vocal fold healing. 
  • Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders. 
  • Adventitial fibroblasts: backstage journeymen. 
  • Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue. 
  • Airway fibroblasts in asthma manifest an invasive phenotype. 
  • Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring. 
  • Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene. 
  • Alterations in TNF- and IL-related gene expression in space-flown WI38 human fibroblasts. 
  • Altered rate of DNA replication in ageing human fibroblast cultures. 
  • Aminoimidazole carboxamide ribonucleoside toxicity: a model for study of pyrimidine starvation. 
  • Amylopectinosis disease isolated to the heart with normal glycogen branching enzyme activity and gene sequence. 
  • An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria. 
  • An experimental model of preretinal neovascularization in the rabbit. 
  • An in vitro investigation into the effects of repetitive motion and nonsteroidal antiinflammatory medication on human tendon fibroblasts. 
  • An inhibitor of nuclear scaffold protease blocks chemical transformation of fibroblasts. 
  • An injectable method for noninvasive spine fusion. 
  • Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17. 
  • Analysis of the glycoproteome of Toxoplasma gondii using lectin affinity chromatography and tandem mass spectrometry. 
  • Angiotensin II stimulates proliferation of adventitial fibroblasts cultured from rat aortic explants. 
  • Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression. 
  • Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes. 
  • Antibacterial efficacy of exogenous nitric oxide on periodontal pathogens. 
  • Antibody against T lymphoblastic leukemia-associated antigen (3-40) identifies vimentin and keratin intermediate filaments in normal cells. 
  • Antifibrotic and uveitogenic properties of gamma interferon in the rabbit eye. 
  • Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations. 
  • Apoptosis and P53 induction in human lung fibroblasts exposed to chromium (VI): effect of ascorbate and tocopherol. 
  • Apoptotic caspases regulate induction of iPSCs from human fibroblasts. 
  • Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. 
  • Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue. 
  • Ascorbic acid specifically increases type I and type III procollagen messenger RNA levels in human skin fibroblast. 
  • Assays to measure plasma membrane and cytoskeletal changes in interferon-treated cells. 
  • Associations between the cells of the walls of Schlemm's canal. 
  • Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis. 
  • Aurora-A kinase is essential for bipolar spindle formation and early development. 
  • Autophagic activity dictates the cellular response to oncogenic RAS. 
  • Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release. 
  • Beta-catenin and transforming growth factor beta have distinct roles regulating fibroblast cell motility and the induction of collagen lattice contraction. 
  • Beta-catenin is a mediator of the response of fibroblasts to irradiation. 
  • Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing. 
  • Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. 
  • Binding and endocytosis of alpha 2-macroglobulin-plasmin complexes. 
  • Binding of deoxyribonuclease I to actin: a new way to visualize microfilament bundles in nonmuscle cells. 
  • Binding of placental lactogen and growth hormone to fetal sheep fibroblasts. 
  • Biochemical and structural studies of tenascin/hexabrachion proteins. 
  • Biocompatibility studies of functionalized regioregular poly(3-hexylthiophene) layers for sensing applications. 
  • Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. 
  • Biostable electrospun microfibrous scaffolds mitigate hypertrophic scar contraction in an immune-competent murine model. 
  • Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice. 
  • Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions. 
  • Brief communication: melanoma-specific antibodies produced in monkeys by immunization with human melanoma cell lines. 
  • CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts. 
  • CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis. 
  • CD34 and dural fibroblasts: the relationship to solitary fibrous tumor and meningioma. 
  • CD34+CD38-lin- cord blood cells develop into dendritic cells in human thymic stromal monolayers and thymic nodules. 
  • CD36 initiates the secretory phenotype during the establishment of cellular senescence. 
  • CD90(+) stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer. 
  • CLN3p impacts galactosylceramide transport, raft morphology, and lipid content. 
  • CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches. 
  • COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. 
  • Ca(2+)-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells. 
  • Ca(2+)-regulated serine protease associated with the nuclear scaffold. 
  • Ca2+-sensitive inactivation and facilitation of L-type Ca2+ channels both depend on specific amino acid residues in a consensus calmodulin-binding motif in the(alpha)1C subunit. 
  • Calcineurin regulates cyclin D1 accumulation in growth-stimulated fibroblasts. 
  • Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma. 
  • Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. 
  • Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes. 
  • Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. 
  • Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers. 
  • Caspase 3 promotes surviving melanoma tumor cell growth after cytotoxic therapy. 
  • Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. 
  • Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response. 
  • Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response. 
  • Cell cycle deregulation and xeroderma pigmentosum group C cell transformation. 
  • Cell migration through defined, synthetic ECM analogs. 
  • Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010. 
  • Cell- and heparin-binding domains of the hexabrachion arm identified by tenascin expression proteins. 
  • Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes. 
  • Cell-type specific regulation of gene expression by simian virus 40 T antigens. 
  • Cellular composition of post-haemorrhagic opacities in the human vitreous. 
  • Cellular energetics and mitochondrial uncoupling in canine aging. 
  • Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis. 
  • Cellular models of hibernating myocardium: implications for future research. 
  • Changes in microfilament organization and surface topogrophy upon transformation of chick embryo fibroblasts with Rous sarcoma virus. 
  • Changes in the behaviour of teratocarcinoma cells cultivated in vitro. 
  • Characterization and comparison of commercially available antinuclear antibody kits using single pattern index sera. 
  • Characterization and distribution of protein kinase C isoforms in human skin fibroblasts. 
  • Characterization of a chemotactic and cytotoxic proteinase from human skin. 
  • Characterization of a chimpanzee anti-human melanoma antiserum. 
  • Characterization of a partial cDNA for lysyl hydroxylase from human skin fibroblasts; lysyl hydroxylase mRNAs are regulated differently by minoxidil derivatives and hydralazine. 
  • Characterization of avian and viral p60src proteins expressed in yeast. 
  • Characterization of melanoma cell membrane tumor-associated antigens using xenoserum, alloserum, and autoserum: I. immunofluorescence. 
  • Characterization of the absence of an unique DNA-binding protein in senescent but not in their young growing and nongrowing counterparts provides the means to mark the final stage of the cellular aging process. 
  • Characterization of the plasminogen receptors of normal and rheumatoid arthritis human synovial fibroblasts. 
  • Characterization of two populations of statin and the relationship of their syntheses to the state of cell proliferation. 
  • Chicken calmodulin promoter activity in proliferating and differentiated cells. 
  • Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest. 
  • Chromium(VI) induces p53-dependent apoptosis in diploid human lung and mouse dermal fibroblasts. 
  • Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle. 
  • Chromosomal organization of adrenergic receptor genes. 
  • Chromosome end-to-end associations and telomerase activity during cancer progression in human cells after treatment with alpha-particles simulating radon progeny. 
  • Click by Click Microporous Annealed Particle (MAP) Scaffolds. 
  • Clinical and laboratory findings in four patients with the non-progressive hepatic form of type IV glycogen storage disease. 
  • Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. 
  • Cloning and molecular characterization of a cDNA clone to statin, a protein specifically expressed in nonproliferating quiescent and senescent fibroblasts. 
  • Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins. 
  • Collagenase production by human dermis in vitro. 
  • Combined immunodeficiency disease associated with adenosine deaminase deficiency. Report on a workshop held in Albany, New York, October 1, 1973. 
  • Comparison of benefits on myocardial performance of cellular cardiomyoplasty with skeletal myoblasts and fibroblasts. 
  • Comparison of two rapid assays for Clostridium difficile Common antigen and a C difficile toxin A/B assay with the cell culture neutralization assay. 
  • Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response. 
  • Control of fibroblast senescence and activation of programmed cell death. 
  • Control of muscle formation by the fusogenic micropeptide myomixer. 
  • Controlling the kinetics of thiol-maleimide Michael-type addition gelation kinetics for the generation of homogenous poly (ethylene glycol) hydrogels 
  • Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling. 
  • Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3. 
  • Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency. 
  • Correction of severe combined immunodeficiency by fetal liver cells. 
  • Correlating nanoscale titania structure with toxicity: a cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. 
  • Covalent immobilization of RGDS on hydrogel surfaces to direct cell alignment and migration. 
  • Creation of human tumour cells with defined genetic elements. 
  • Critical role of chromium (Cr)-DNA interactions in the formation of Cr-induced polymerase arresting lesions. 
  • Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications. 
  • Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells. 
  • Cytogenetic engineering in vivo: restoration of biologic complement activity to C5-deficient mice by intravenous inoculation of hybrid cells. 
  • Cytoplasmic localization of the transforming protein of Fujinami sarcoma virus: salt-sensitive association with subcellular components. 
  • Cytoplasmic polyadenylation element binding protein deficiency stimulates PTEN and Stat3 mRNA translation and induces hepatic insulin resistance. 
  • DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway. 
  • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. 
  • Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy. 
  • Decreased expression of lysyl hydroxylase 2 (LH2) in skin fibroblasts from three Ehlers-Danlos patients does not result from mutations in either the coding or proximal promoter region of the LH2 gene. 
  • Defective phorbol ester-stimulated secretion of beta-amyloid precursor protein from Alzheimer's disease fibroblasts. 
  • Defective potassium currents in ataxia telangiectasia fibroblasts. 
  • Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria. 
  • Definition of distinct compartments in polarized Madin-Darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling. 
  • Definitive prenatal diagnosis for type III glycogen storage disease. 
  • Delta-like 1-Lysine613 regulates notch signaling. 
  • Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. 
  • Developmental regulation of insulin-like growth factor binding protein production: studies in fetal, postnatal, and pregnant sheep. 
  • Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. 
  • Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI. 
  • Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα. 
  • Different mechanisms preclude mutant CLDN14 proteins from forming tight junctions in vitro. 
  • Different secretory pathways of renin from mouse cells transfected with the human renin gene. 
  • Differential cell responses to nanoparticle docetaxel and small molecule docetaxel at a sub-therapeutic dose range. 
  • Differential collagen I gene expression in fetal fibroblasts. 
  • Differential effects of interleukin-1 alpha, tumor necrosis factor-alpha, indomethacin, hydrocortisone, and macrophage co-culture on the proliferation of human fibroblasts and peritoneal mesothelial cells. 
  • Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts. 
  • Differential expression of plasminogen activators and their inhibitors in an organotypic skin coculture system. 
  • Differential expression of procollagen genes between mid- and late-gestational fetal fibroblasts. 
  • Differential labelling of UDP-N-acetylglucosamine in Huntington's-chorea fibroblasts. 
  • Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression. 
  • Differentiation of Human Induced Pluripotent Stem Cells into Epicardial-Like Cells. 
  • Diffusion of low density lipoprotein-receptor complex on human fibroblasts. 
  • Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines. 
  • Direct reprogramming of cardiac fibroblasts to cardiomyocytes using microRNAs. 
  • Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells. 
  • Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation. 
  • Disappearance of the telomere dysfunction-induced stress response in fully senescent cells. 
  • Disruption of crosstalk between mesenchymal stromal and tumor cells in bone marrow as a therapeutic target to prevent metastatic bone disease. 
  • Distinct function of estrogen receptor α in smooth muscle and fibroblast cells in prostate development. 
  • Distinct requirements for Ras oncogenesis in human versus mouse cells. 
  • Distribution of repair-incorporated nucleotides and nucleosome rearrangement in the chromatin of normal and xeroderma pigmentosum human fibroblasts. 
  • Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. 
  • Diversity, topographic differentiation, and positional memory in human fibroblasts. 
  • Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. 
  • Dual action of TGF-beta1 on nasal-polyp derived fibroblasts. 
  • Dupuytren's fibroblast contractility by sphingosine-1-phosphate is mediated through non-muscle myosin II. 
  • Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. 
  • Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture. 
  • Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin. 
  • Effects of epidermal growth factor on fibroblast migration through biomimetic hydrogels. 
  • Effects of glutathione on chromium-induced DNA crosslinking and DNA polymerase arrest. 
  • Effects of nitric oxide releasing poly(vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice. 
  • Effects of repetitive motion on human fibroblasts. 
  • Effects of topical glaucoma drugs on fistulized rabbit conjunctiva. 
  • Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (Hemagglutinating Virus of Japan)--liposome method. 
  • Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle. 
  • Electrical properties of implant encapsulation tissue. 
  • Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level. 
  • Elevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro. 
  • Elevation of Stromal-Derived Mediators of Inflammation Promote Prostate Cancer Progression in African-American Men. 
  • Elimination of mycoplasma from human B-lymphoblastoid cell lines. 
  • Encapsulation of Adenovirus BMP2-Transduced Cells with PEGDA Hydrogels Allows Bone Formation in the Presence of Immune Response. 
  • Endochondral bone formation from hydrogel carriers loaded with BMP2-transduced cells. 
  • Endothelial cells adhere to the RGD domain and the fibrinogen-like terminal knob of tenascin. 
  • Engineering prokaryotic channels for control of mammalian tissue excitability. 
  • Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain. 
  • Enhanced efficacy of an AAV vector encoding chimeric, highly secreted acid alpha-glucosidase in glycogen storage disease type II. 
  • Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region. 
  • Enzyme-Responsive Delivery of Multiple Proteins with Spatiotemporal Control 
  • Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus. 
  • Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. 
  • Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene. 
  • Ethylmalonic aciduria: an organic acidemia with CNS involvement and vasculopathy. 
  • Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts. 
  • Evidence for a striking increase in acetylcholinesterase activity in cultured human fibroblasts which are trisomic for chromosome two. 
  • Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis. 
  • Experimental traction retinal detachment in the cat. 
  • Expression of RANKL in osteolytic membranes: association with fibroblastic cell markers. 
  • Expression of a murine cytomegalovirus early-late protein in "latently" infected mice. 
  • Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. 
  • Expression of murine leukemia virus structural antigens on the surface of chemically induced murine sarcomas. 
  • Expression of recombinant human methylmalonyl-CoA mutase: in primary mut fibroblasts and Saccharomyces cerevisiae. 
  • Expression of terminin, a senescence-related cytoplasmic protein, in the aging rat brain. 
  • Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma. 
  • Extracellular low pH affects circadian rhythm expression in human primary fibroblasts. 
  • FKBP12 is not required for the modulation of transforming growth factor beta receptor I signaling activity in embryonic fibroblasts and thymocytes. 
  • Fanconi anemia complementation group A cells are hypersensitive to chromium(VI)-induced toxicity. 
  • Fibrillar systems in cell motility. 
  • Fibroblastic rheumatism: a report of 4 cases with potential therapeutic implications. 
  • Fibroblasts in Huntington's disease. 
  • Fibroblasts that express aromatic amino acid decarboxylase have increased sensitivity to the synergistic cytotoxicity of L-dopa and manganese. 
  • Fibronectin and beta-catenin act in a regulatory loop in dermal fibroblasts to modulate cutaneous healing. 
  • Fibrovascular ingrowth as a cause of Ahmed glaucoma valve failure in children. 
  • Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process. 
  • Fluorescence in situ hybridization method for measuring transfection efficiency. 
  • Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin. 
  • Fluorescent low density lipoprotein for observation of dynamics of individual receptor complexes on cultured human fibroblasts. 
  • Force fluctuations in three-dimensional suspended fibroblasts. 
  • Frog oocytes synthesize and completely process the precursor polypeptide to virion structural proteins after microinjection of avian myeloblastosis virus RNA. 
  • Functional Advantages of Porphyromonas gingivalis Vesicles. 
  • Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. 
  • Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro. 
  • G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. 
  • G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases. 
  • G-Protein-Coupled Receptors in Heart Disease. 
  • Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin. 
  • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. 
  • Gene expression phenotypes of oncogenic signaling pathways. 
  • Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. 
  • Generation and customization of biosynthetic excitable tissues for electrophysiological studies and cell-based therapies. 
  • Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX. 
  • Generation of a fibroblast chemotactic factor in serum by activation of complement. 
  • Generation of melanoma-specific, cytotoxic CD4(+) T helper 2 cells: requirement of both HLA-DR15 and Fas antigens on melanomas for their lysis by Th2 cells. 
  • Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice. 
  • Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. 
  • Genetic analysis of susceptibility to Chlamydia trachomatis in mouse. 
  • Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor). 
  • Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases. 
  • Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D. 
  • Genome-wide identification of autosomal genes with allelic imbalance of chromatin state. 
  • Genomic analysis of human lung fibroblasts exposed to vanadium pentoxide to identify candidate genes for occupational bronchitis. 
  • Genotype, phenotype, and outcomes of nine patients with T-B+NK+ SCID. 
  • Germline AGO2 mutations impair RNA interference and human neurological development. 
  • Glucocorticosteroid inhibition of intraocular proliferation after injury. 
  • Glucosamine dependence of Huntington's chorea fibroblasts in culture. 
  • Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo. 
  • Glutamine attenuation of cell death and inducible nitric oxide synthase expression following inflammatory cytokine-induced injury is dependent on heat shock factor-1 expression. 
  • Glutamine's protection against cellular injury is dependent on heat shock factor-1. 
  • Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression. 
  • Glutaric aciduria type I: unusual biochemical presentation. 
  • Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts. 
  • Gp91phox contributes to NADPH oxidase activity in aortic fibroblasts but not smooth muscle cells. 
  • Granular presence of terminin is the marker to distinguish between the senescent and quiescent states. 
  • Graphene Enhances Actin Filament Assembly Kinetics and Modulates NIH-3T3 Fibroblast Cell Spreading. 
  • Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells. 
  • Growth factors modulate gonadotropin receptor induction in granulosa cell cultures. 
  • Growth factors regulate beta-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing. 
  • Growth inhibition of human Tenon's capsule fibroblasts and rabbit dermal fibroblasts with non-carcinogenic N-alkylated anthracyclines. 
  • Growth rate of control and beta-interferon-treated human fibroblast populations over the course of their in vitro life span. 
  • Guanylate Binding Proteins Restrict Leishmania donovani Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting. 
  • Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. 
  • H(2)O(2)-induced O(2) production by a non-phagocytic NAD(P)H oxidase causes oxidant injury. 
  • HER-2/c-erbB2 is phosphorylated by calmodulin-dependent protein kinase II on a single site in the cytoplasmic tail at threonine-1172. 
  • HL-A antigenic loss in malignant transformation. 
  • HSV-1 amplicon vector-mediated expression of ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype. 
  • Haem oxygenase-1 prevents cell death by regulating cellular iron. 
  • Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis. 
  • Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. 
  • Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. 
  • Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular function. 
  • Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin. 
  • Heterogeneity of Genotypic and phenotypic characteristics of fifteen permanent cell lines derived from human gliomas. 
  • Heterogeneous basis of the type VIB form of Ehlers-Danlos syndrome (EDS VIB) that is unrelated to decreased collagen lysyl hydroxylation. 
  • Hexabrachion proteins in embryonic chicken tissues and human tumors. 
  • Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction. 
  • High-Efficiency Cellular Reprogramming by Nanoscale Puncturing. 
  • High-level production of recombinant human lysosomal acid alpha-glucosidase in Chinese hamster ovary cells which targets to heart muscle and corrects glycogen accumulation in fibroblasts from patients with Pompe disease. 
  • Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis. 
  • Histopathologic and ultrastructural features of surgically excised subfoveal choroidal neovascular lesions: submacular surgery trials report no. 7. 
  • Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2. 
  • How vinculin regulates force transmission. 
  • Human Vascular Microphysiological System for in vitro Drug Screening. 
  • Human cardiac fibroblasts and receptors for angiotensin II and bradykinin: a potential role for bradykinin in the modulation of cardiac extracellular matrix. 
  • Human distal lung maps and lineage hierarchies reveal a bipotent progenitor. 
  • Human mesenchymal stem cell and epithelial hepatic carcinoma cell lines in admixture: concurrent stimulation of cancer-associated fibroblasts and epithelial-to-mesenchymal transition markers. 
  • Human recombinant interleukin-1 alpha increases elastase-like enzyme in human uterine cervical fibroblasts. 
  • Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein. 
  • Huntington's disease: membrane abnormalities and protein glycosylation. 
  • Huntington's-chorea fibroblasts. Cellular protein glycosylation. 
  • Hydralazine differentially increases mRNAs for the alpha and beta subunits of prolyl 4-hydroxylase whereas it decreases pro alpha 1(I) collagen mRNAs in human skin fibroblasts. 
  • Hydrogel microsphere encapsulation of a cell-based gene therapy system increases cell survival of injected cells, transgene expression, and bone volume in a model of heterotopic ossification. 
  • Hypoxia precedes the development of experimental preretinal neovascularization. 
  • IFN-{beta} signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesenchymal progenitors. 
  • IGF2 is critical for tumorigenesis by synovial sarcoma oncoprotein SYT-SSX1. 
  • IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells. 
  • IL-13 and IL-1beta promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Ralpha. 
  • IRGM1 links mitochondrial quality control to autoimmunity. 
  • Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells. 
  • Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration. 
  • Identification of 3-methylglutarylcarnitine. A new diagnostic metabolite of 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency. 
  • Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid. 
  • Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence. 
  • Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma. 
  • Identification of the segments of the mouse transferrin receptor 1 required for mouse mammary tumor virus infection. 
  • Identifying constitutive and context-specific molecular-tension-sensitive protein recruitment within focal adhesions. 
  • Immune status assay (ISA): a noninvasive procedure for studying allograft rejection. 
  • Immunoblot analyses of glycogen debranching enzyme in different subtypes of glycogen storage disease type III. 
  • Immunochemical and biochemical characterization of a glioma-associated extracellular matrix glycoprotein. 
  • Immunocytochemical localization of chemoattractant proteinase in whole human skin, fibroblasts, lymphocytes, and granulocytes. 
  • Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum. 
  • Immunohistochemical localization of epidermal growth factor in cat paradental tissues during tooth movement. 
  • Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. 
  • Immunoreactive forms of human erythrocyte ankyrin are present in diverse cells and tissues. 
  • Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis. 
  • Improvement in efficacy of corticosteroid therapy in an animal model of proliferative vitreoretinopathy by pretreatment. 
  • Improvements to the differential display method for gene analysis. 
  • In regard to Arvold et al. (Int J Radiat Oncol Biol Phys 2005;62:207-212). 
  • In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1. 
  • In vitro characteristics of Tenon's fibroblast lines derived from pediatric and adult eyes do not fully explain pediatric glaucoma surgery failure: a preliminary report. 
  • In vitro interactions between DMSA-coated maghemite nanoparticles and human fibroblasts: A physicochemical and cyto-genotoxical study. 
  • In vivo modulation of macrophage tumoricidal activity: enhanced tumor cell killing by peritoneal macrophages from mice given injections of sodium periodate. 
  • Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. 
  • Inborn errors of molybdenum metabolism: combined deficiencies of sulfite oxidase and xanthine dehydrogenase in a patient lacking the molybdenum cofactor. 
  • Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies. 
  • Increased calmodulin affects cell morphology and mRNA levels of cytoskeletal protein genes. 
  • Increased organization of cytoskeleton accompanying the aging of human fibroblasts in vitro. 
  • Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient. 
  • Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. 
  • Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy. 
  • Induction of human tenascin (neuronectin) by growth factors and cytokines: cell type-specific signals and signalling pathways. 
  • Induction of pro-apoptotic and cell cycle-inhibiting genes in chromium (VI)-treated human lung fibroblasts: lack of effect of ERK. 
  • Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. 
  • Infantile sialic acid storage disease: a rare cause of cytoplasmic vacuolation in pediatric patients. 
  • Infection of artificial air pouches in the connective tissue of mice with Neisseria gonorrhoeae. 
  • Influence of ATM function on telomere metabolism. 
  • Influence of threonine metabolism on S-adenosylmethionine and histone methylation. 
  • Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis. 
  • Inhibition of Human Adenovirus Replication by the Importin α/β1 Nuclear Import Inhibitor Ivermectin. 
  • Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. 
  • Inhibition of human subconjunctival fibroblast proliferation by immunotoxin. 
  • Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth. 
  • Inhibition of platelet-derived growth factor-BB-induced fibroblast proliferation by plasmin-activated alpha 2-macroglobulin is mediated via an alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein-dependent mechanism. 
  • Insights from a chimpanzee adipose stromal cell population: opportunities for adult stem cells to expand primate functional genomics. 
  • Integrating light-sheet imaging with virtual reality to recapitulate developmental cardiac mechanics 
  • Interaction of retinal glial cells with collagen matrices: implications for pathogenesis of cell-mediated vitreous traction. 
  • Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice. 
  • Interferon effects on microfilament organization, cellular fibronectin distribution, and cell motility in human fibroblasts. 
  • Interferon increases the abundance of submembranous microfilaments in HeLa-S3 cells in suspension culture. 
  • Interferon inhibits the redistribution of cell surface components. 
  • Interferon production in mixed cultures of murine leukocytes and syngeneic L1210 leukemia cells. 
  • Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma. 
  • Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma. 
  • Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta. 
  • Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest. 
  • In vitro generation of renal tubular epithelial cells from fibroblasts: implications for precision and regenerative medicine in nephrology. 
  • Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells. 
  • Isolated sulfite oxidase deficiency: mutation analysis and DNA-based prenatal diagnosis. 
  • Isolated sulfite oxidase deficiency: review of two cases in one family. 
  • Isolation of a cDNA clone complementary to sequences for a 34-kilodalton protein which is a pp60v-src substrate. 
  • Klotho and phosphate are modulators of pathologic uremic cardiac remodeling. 
  • L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine. 
  • LKB1 reduces ROS-mediated cell damage via activation of p38. 
  • Lack of Thy1 defines a pathogenic fraction of cardiac fibroblasts in heart failure. 
  • Laser-scanning lithography (LSL) for the soft lithographic patterning of cell-adhesive self-assembled monolayers. 
  • Latex nanosphere delivery system (LNDS): novel nanometer-sized carriers of fluorescent dyes and active agents selectively target neuronal subpopulations via uptake and retrograde transport. 
  • Leptin mediates the parathyroid hormone-related protein paracrine stimulation of fetal lung maturation. 
  • Life with too much polyprenol: polyprenol reductase deficiency. 
  • Liposomes-entrapped chondroitin sulphate: ultrastructural characterization and in vitro biocompatibility. 
  • Lithographic patterning of photoreactive cell-adhesive proteins. 
  • Live fate-mapping of joint-associated fibroblasts visualizes expansion of cell contributions during zebrafish fin regeneration. 
  • Liver X receptor is a regulator of orphan nuclear receptor NOR-1 gene transcription in adipocytes. 
  • Loading effect of fibroblast-myocyte coupling on resting potential, impulse propagation, and repolarization: insights from a microstructure model. 
  • Localized delivery of DNA to the cells by viral collagen-loaded silica colloidal crystals. 
  • Long-term survival of influenza virus infected club cells drives immunopathology. 
  • Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination. 
  • Loss of atm radiosensitizes multiple p53 null tissues. 
  • Loss of microRNA-21 leads to profound stromal remodeling and short survival in K-Ras-driven mouse models of pancreatic cancer. 
  • Lysine hydroxylation of collagen in a fibroblast cell culture system. 
  • MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300. 
  • MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. 
  • Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. 
  • Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta. 
  • Mapping of peroxyl radical induced damage on genomic DNA. 
  • Mapping oxidative DNA damage at nucleotide level. 
  • Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology. 
  • Matrix produced by diseased cardiac fibroblasts affects early myotube formation and function. 
  • Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy. 
  • Measurement of oxidative DNA damage in the human p53 and PGK1 gene at nucleotide resolution. 
  • Mechanism of apoptosis and determination of cellular fate in chromium(VI)-exposed populations of telomerase-immortalized human fibroblasts. 
  • Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. 
  • Membrane abnormalities of Huntington's chorea fibroblasts in culture. 
  • Metabolic regulation of collagen I in fibroblasts isolated from normal peritoneum and adhesions by dichloroacetic acid. 
  • Metal ion-dependent hydrogen peroxide-induced DNA damage is more sequence specific than metal specific. 
  • Methylation of deoxycytidine incorporated by excision-repair synthesis of DNA. 
  • MicroRNA induced cardiac reprogramming in vivo: evidence for mature cardiac myocytes and improved cardiac function. 
  • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. 
  • MicroRNAs and Cardiac Regeneration. 
  • MicroRNAs in skin tissue engineering. 
  • MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes. 
  • Microarray analysis of E-box binding-related gene expression in young and replicatively senescent human fibroblasts. 
  • Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1. 
  • Micropatterning of poly(ethylene glycol) diacrylate hydrogels. 
  • Microporous annealed particle hydrogel stiffness, void space size, and adhesion properties impact cell proliferation, cell spreading, and gene transfer. 
  • Mindin (SPON2) Is Essential for Cutaneous Fibrogenesis in a Mouse Model of Systemic Sclerosis. 
  • Minor RNA and other components of host origin intrinsic to avian leukosis virus particles. 
  • Minoxidil inhibits ocular cell proliferation and lysyl hydroxylase activity. 
  • Missense mutation in a von Willebrand factor type A domain of the alpha 3(VI) collagen gene (COL6A3) in a family with Bethlem myopathy. 
  • Missense variants in the chromatin remodeler CHD1 are associated with neurodevelopmental disability. 
  • Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia. 
  • Mitochondrial dysfunction in ataxia-telangiectasia. 
  • Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. 
  • Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection. 
  • Mobility and distribution of a cell surface glycoprotein and its interaction with other membrane components. 
  • Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1. 
  • Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity. 
  • Modelling cardiac fibroblasts: interactions with myocytes and their impact on impulse propagation. 
  • Modification of surfaces with cell adhesion peptides alters extracellular matrix deposition. 
  • Modulation of conduction velocity by nonmyocytes in the low coupling regime. 
  • Modulation of the transformed and neoplastic phenotype of rat fibroblasts by MHC-I gene expression. 
  • Molecular abnormalities of human plasminogen isolated from synovial fluid of rheumatoid arthritis patients. 
  • Molecular analysis of genetic instability caused by chronic inflammation. 
  • Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase. 
  • Molecular mechanisms of receptor desensitization using the beta-adrenergic receptor-coupled adenylate cyclase system as a model. 
  • Morphological and neoplastic transformation of C3H/10T1/2 Cl 8 mouse embryo cells by insoluble carcinogenic nickel compounds. 
  • Mouse adenovirus type 1 infection of adipose tissue. 
  • Multiple assay characterization of murine monoclonal antimelanoma antibodies. 
  • Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells. 
  • Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector. 
  • Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome. 
  • Mutations near amino end of alpha1(I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing. 
  • Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration. 
  • Myc requires distinct E2F activities to induce S phase and apoptosis. 
  • Myocardial injury-induced fibroblast proliferation facilitates retroviral-mediated gene transfer to the rat heart in vivo. 
  • Myotonic muscular dystrophy: morphology, histochemistry, and growth characteristics of cultured skin fibroblasts. 
  • N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias. 
  • Nano-C60 cytotoxicity is due to lipid peroxidation. 
  • Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging. 
  • Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). 
  • Neuronal-glial interactions: complexity of neurite outgrowth correlates with substrate adhesivity of serotonergic neurons. 
  • Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression. 
  • Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts. 
  • Optic nerve tissue sections derived from myelin-deficient mutant mice as culture substrata for fibroblast adhesion and spreading. 
  • Optimizing delivery for efficient cardiac reprogramming. 
  • Organotypic models of type III interferon-mediated protection from Zika virus infections at the maternal-fetal interface. 
  • Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer. 
  • Outside-in Signaling by Adventitial Fibroblasts. 
  • Overexpression of lysyl oxidase to increase matrix crosslinking and improve tissue strength in dermal wound healing. 
  • P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. 
  • PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro. 
  • PDGF-stimulated fibroblast proliferation is enhanced synergistically by receptor-recognized alpha 2-macroglobulin. 
  • PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer-associated fibroblasts. 
  • PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance. 
  • Pathogenesis of radiation-induced capsular contracture in tissue expander and implant breast reconstruction. 
  • Pathways Governing Polyethylenimine Polyplex Transfection in Microporous Annealed Particle Scaffolds. 
  • Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression. 
  • Pax7 expressing cells contribute to dermal wound repair, regulating scar size through a β-catenin mediated process. 
  • Pericardial cells for graft seeding: isolation, culture and identification. 
  • Perivascular Fibro-Adipogenic Progenitor Tracing during Post-Traumatic Osteoarthritis. 
  • Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice. 
  • Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP). 
  • Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression. 
  • Phosphorylation at tyrosine 262 promotes GADD34 protein turnover. 
  • Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor. 
  • Photocrosslinkable polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering. 
  • Photolithographic patterning of polyethylene glycol hydrogels. 
  • Placental lactogen-binding sites in isolated fetal fibroblasts: characterization, processing, and regulation. 
  • Plasminogen activation stimulates an increase in intracellular calcium in human synovial fibroblasts. 
  • Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies. 
  • Pleomorphic fibroma of the eyelid. 
  • Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function. 
  • Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration. 
  • Polypeptides of avian RNA tumor viruses. V. Analysis of the virus core. 
  • Positively selected Leu-11a (CD16+) cells require the presence of accessory cells or factors for the lysis of herpes simplex virus-infected fibroblasts but not herpes simplex virus-infected Raji. 
  • Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage. 
  • Predicting cross-reactive immunological material (CRIM) status in Pompe disease using GAA mutations: lessons learned from 10 years of clinical laboratory testing experience. 
  • Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver. 
  • Preparation and screening of an arrayed human genomic library generated with the P1 cloning system. 
  • Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness. 
  • Production of Cardiomyocytes by microRNA-Mediated Reprogramming in Optimized Reprogramming Media. 
  • Production of cytokines around loosened cemented acetabular components. Analysis with immunohistochemical techniques and in situ hybridization. 
  • Proliferation and apoptosis of fibroblasts and smooth muscle cells in rat uterine cervix throughout gestation and the effect of the antiprogesterone onapristone. 
  • PromISR-6, a Guanabenz Analogue, Improves Cellular Survival in an Experimental Model of Huntington's Disease. 
  • Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development. 
  • Protein tyrosine phosphatase (PTP) inhibition enhances chromosomal stability after genotoxic stress: decreased chromosomal instability (CIN) at the expense of enhanced genomic instability (GIN)? 
  • Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress. 
  • Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation. 
  • Pseudomelanomas after conservative management of uveal melanoma. 
  • Pulmonary fibrosis: thinking outside of the lung. 
  • Purification of recombinant human precursor acid alpha-glucosidase. 
  • Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading. 
  • Quantification of cellular proliferation in experimental proliferative vitreoretinopathy. 
  • Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment. 
  • Quantitation of cell area on glass and fibronectin-coated surfaces by digital image analysis. 
  • RANK, RANKL, OPG, and M-CSF expression in stromal cells during corneal wound healing. 
  • RB regulates transcription of the p21/WAF1/CIP1 gene. 
  • RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription. 
  • RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into c-kit(+) Cardiac Progenitor Cells. 
  • Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. 
  • Rapid diagnosis of late-onset Pompe disease by fluorometric assay of alpha-glucosidase activities in dried blood spots. 
  • Rapid disappearance of statin, a nonproliferating and senescent cell-specific protein, upon reentering the process of cell cycling. 
  • Rapid healing of femoral defects in rats with low dose sustained BMP2 expression from PEGDA hydrogel microspheres. 
  • Rare disorders of metabolism with elevated butyryl- and isobutyryl-carnitine detected by tandem mass spectrometry newborn screening. 
  • Recombinant human acid alpha-glucosidase corrects acid alpha-glucosidase-deficient human fibroblasts, quail fibroblasts, and quail myoblasts. 
  • Recombinant human uteroglobin inhibits the in vitro invasiveness of human metastatic prostate tumor cells and the release of arachidonic acid stimulated by fibroblast-conditioned medium. 
  • Recombinants within the tyrosine kinase region of v-abl and v-src identify a v-abl segment that confers lymphoid specificity. 
  • Red blood cell and fibroblast membranes in Duchenne and myotonic muscular dystrophy. 
  • Reduced GABA synthesis in pyridoxine-dependent seizures. 
  • Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. 
  • Reduced prostate branching morphogenesis in stromal fibroblast, but not in epithelial, estrogen receptor α knockout mice. 
  • Regeneration of fat cells from myofibroblasts during wound healing. 
  • Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein. 
  • Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. 
  • Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination. 
  • Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. 
  • Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I. 
  • Regulation of lysyl oxidase mRNA in dermal fibroblasts from normal donors and patients with inherited connective tissue disorders. 
  • Regulation of mammalian horizontal gene transfer by apoptotic DNA fragmentation. 
  • Regulation of sugar transport in cultured diploid human skin fibroblasts. 
  • Regulation of transcription factor NFAT by ADP-ribosylation. 
  • RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts. 
  • Relationship between 3T3 cell spreading and the strength of adhesion on glass and silane surfaces. 
  • Removal of fibroblasts from human epithelial cell cultures with use of a complement fixing monoclonal antibody reactive with human fibroblasts and monocytes/macrophages. 
  • Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation. 
  • Resistance to apoptosis, increased growth potential, and altered gene expression in cells that survived genotoxic hexavalent chromium [Cr(VI)] exposure. 
  • Resorbable, amino acid-based poly(ester urea)s crosslinked with osteogenic growth peptide with enhanced mechanical properties and bioactivity. 
  • Retrospective diagnosis of carnitine-acylcarnitine translocase deficiency by acylcarnitine analysis in the proband Guthrie card and enzymatic studies in the parents. 
  • Retroviral vector gene expression in F9 embryonal carcinoma cells. 
  • Reversion from deficiency of galactose-1-phosphate uridylytransferase (GALT) in an SV40-transformed human fibroblast line. 
  • Revertants and partial transformants of rat fibroblasts infected with Fujinami sarcoma virus. 
  • Ribosomal RNA in avian leukosis virus particles. 
  • Rig1 receptor plays a critical role in cardiac reprogramming via YY1 signaling. 
  • Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13-Suppressed Elastin in Airway Fibroblasts in Asthma. 
  • Role of hyaluronan and hyaluronan-binding proteins in human asthma. 
  • SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence. 
  • Screening for Pompe disease using a rapid dried blood spot method: experience of a clinical diagnostic laboratory. 
  • Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog. 
  • Senescent fibroblasts resist apoptosis by downregulating caspase-3. 
  • Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. 
  • Sensitive quantitation of chromium-DNA adducts by inductively coupled plasma mass spectrometry with a direct injection high-efficiency nebulizer. 
  • Sequence analysis of a cDNA for lysyl hydroxylase isolated from human skin fibroblasts from a normal donor: differences from human placental lysyl hydroxylase cDNA. 
  • Simultaneous proteomic profiling of four different growth states of human fibroblasts, using amine-reactive isobaric tagging reagents and tandem mass spectrometry. 
  • Simultaneous stretching and contraction of stress fibers in vivo. 
  • Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor α. 
  • Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism. 
  • Slow-release nanoparticle-encapsulated delivery system for laryngeal injection. 
  • Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. 
  • Soluble recombinant neutral endopeptidase (CD10) as a potential antiinflammatory agent. 
  • Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells. 
  • Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. 
  • Species variability in angiotensin receptor expression by cultured cardiac fibroblasts and the infarcted heart. 
  • Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. 
  • Stem Cell Surface Marker Expression Defines Late Stages of Reprogramming to Pluripotency in Human Fibroblasts. 
  • Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts. 
  • Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma. 
  • Stromelysin-3 is overexpressed by stromal elements in primary non-small cell lung cancers and regulated by retinoic acid in pulmonary fibroblasts. 
  • Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay. 
  • Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidence that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype. 
  • Successful diagnosis of HIBCH deficiency from exome sequencing and positive retrospective analysis of newborn screening cards in two siblings presenting with Leigh's disease. 
  • Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211. 
  • Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis. 
  • TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles. 
  • TTBK2 controls cilium stability by regulating distinct modules of centrosomal proteins. 
  • Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells. 
  • Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. 
  • Targeting Akt3 signaling in malignant melanoma using isoselenocyanates. 
  • Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. 
  • Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome. 
  • Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma-centric paradigm. 
  • Telomerase activity in normal leukocytes and in hematologic malignancies. 
  • Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling. 
  • The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue. 
  • The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. 
  • The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter. 
  • The RGD motif in fibronectin is essential for development but dispensable for fibril assembly. 
  • The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. 
  • The antiproliferative effect of a transferrin-toxin on human retinal pigment epithelial cells and rabbit fibroblasts. 
  • The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. 
  • The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure. 
  • The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis. 
  • The disappearance of a cyclin-like protein and the appearance of statin is correlated with the onset of differentiation during myogenesis in vitro. 
  • The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. 
  • The effect of combined daunorubicin and triamcinolone acetonide treatment on a refined experimental model of proliferative vitreoretinopathy. 
  • The effect of fluid shear stress upon cell adhesion to fibronectin-treated surfaces. 
  • The effect of halothane on cultured fibroblasts and neuroblastoma cells. 
  • The effects of intravitreal triamcinolone acetonide on experimental pre-retinal neovascularization. 
  • The expression of platelet-derived growth-factor gene in Dupuytren contracture. 
  • The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding. 
  • The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. 
  • The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. 
  • The interaction of a series of hybridoma IgGs with reovirus particles. Demonstration that the core protein lambda 2 is exposed on the particle surface. 
  • The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability. 
  • The mRNA and the activity of lysyl hydroxylase are up-regulated by the administration of ascorbate and hydralazine to human skin fibroblasts from a patient with Ehlers-Danlos syndrome type VI. 
  • The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis. 
  • The nuclear receptor RORα protects against angiotensin II-induced cardiac hypertrophy and heart failure. 
  • The nucleic acid scavenger polyamidoamine third-generation dendrimer inhibits fibroblast activation and granulation tissue contraction. 
  • The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts. 
  • The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice. 
  • The placental lactogen receptor in maternal and fetal sheep liver: regulation by glucose and role in the pathogenesis of fasting during pregnancy. 
  • The relationship between cardiac endothelium and fibroblasts: it's complicated. 
  • The role of leukocyte adhesion molecules in cellular interactions: implications for the pathogenesis of inflammatory synovitis. 
  • The role of osteopontin and osteopontin aptamer (OPN-R3) in fibroblast activity. 
  • The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation. 
  • The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction. 
  • The unfolded protein response triggers selective mRNA release from the endoplasmic reticulum. 
  • Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice. 
  • Thrombospondin-1 is a major activator of TGF-beta1 in vivo. 
  • Tissue engineering for meniscus repair. 
  • Tissue factor de-encryption: ionophore treatment induces changes in tissue factor activity by phosphatidylserine-dependent and -independent mechanisms. 
  • Tissue specificity of a new splice form of the human lysyl hydroxylase 2 gene. 
  • Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs. 
  • Tissue-specific expression and regulation of the alternatively-spliced forms of lysyl hydroxylase 2 (LH2) in human kidney cells and skin fibroblasts. 
  • Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation. 
  • Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. 
  • Transcriptional components of anteroposterior positional information during zebrafish fin regeneration. 
  • Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. 
  • Transformation of chicken embryo fibroblasts and tumor induction by the middle T antigen of polyomavirus carried in an avian retroviral vector. 
  • Transgenic mice for in vivo epigenome editing with CRISPR-based systems. 
  • Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma. 
  • Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression. 
  • Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli. 
  • Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts. 
  • Tumour suppressor genes and angiogenesis: the role of TP53 in fibroblasts. 
  • Two different types of granulocyte colony-stimulating factor produced by bovine lung tissue. 
  • Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. 
  • UVC-induced mitochondrial degradation via autophagy correlates with mtDNA damage removal in primary human fibroblasts. 
  • Up-regulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation-induced apoptosis. 
  • Up-regulation of the alpha2-macroglobulin signaling receptor on rheumatoid synovial fibroblasts. 
  • VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling. 
  • Vanadium-induced HB-EGF expression in human lung fibroblasts is oxidant dependent and requires MAP kinases. 
  • Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase. 
  • Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling. 
  • Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases. 
  • Viral glycoprotein synthesis under conditions of glucosamine block in cells transformed by avian sarcoma viruses. 
  • Wound contraction is attenuated by fasudil inhibition of Rho-associated kinase. 
  • Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP. 
  • Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis. 
  • [Chicken RNA tumor viruses: a model for virus-induced carcinogenesis]. 
  • [Familial Alzheimer's disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts]. 
  • beta -Arrestins regulate protease-activated receptor-1 desensitization but not internalization or Down-regulation. 
  • beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. 
  • beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. 
  • beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1. 
  • c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF. 
  • c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts. 
  • hMad4, c-Myc endogenous inhibitor, induces a replicative senescence-like state when overexpressed in human fibroblasts. 
  • iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors. 
  • p38 mitogen-activated protein kinase regulates growth factor-induced mitogenesis of rat pulmonary myofibroblasts. 
  • p53-dependent control of transactivation of the Pen2 promoter by presenilins. 
  • zipper Nonmuscle myosin-II functions downstream of PS2 integrin in Drosophila myogenesis and is necessary for myofibril formation. 
  • β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. 
• 

  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bradford, William Dalton, Professor of Pathology, Pathology
  • Bursac, Nenad, Professor of Biomedical Engineering, Biomedical Engineering
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Cohen, Seth Morris, Professor of Head and Neck Surgery & Communication Sciences, Head and Neck Surgery & Communication Sciences
  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Henriquez, Craig S., Professor of Biomedical Engineering, Biomedical Engineering
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Integrative Immunobiology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Taylor, Gregory Alan, Professor in Medicine, Integrative Immunobiology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology