Fixatives

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  Subject Areas on Research

  • A fixative for use in muscle histochemistry. 
  • A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer. 
  • A methodology for utilization of predictive genomic signatures in FFPE samples. 
  • Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma. 
  • Array-based comparative genomic hybridization from formalin-fixed, paraffin-embedded breast tumors. 
  • Clinical studies of hemodialysis access through formaldehyde-fixed arterial allografts. 
  • Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies. 
  • ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms. 
  • Genome-wide localization of replication factors. 
  • Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content. 
  • Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas. 
  • In vivo analysis of white adipose tissue in zebrafish. 
  • Integrative molecular profiling of routine clinical prostate cancer specimens. 
  • Kinetic study of collagen fixation with polyepoxy fixatives. 
  • Morphological survey of teleost organs important in carcinogenesis with attention to fixation. 
  • Mosquito coil emissions and health implications. 
  • Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: the UNC SPORE experience. University of North Carolina Specialized Program of Research Excellence. 
  • Preferential sputtering effects in the ion microanalysis of biological tissues. 
  • Preparation of thin, fine-grained, tantalum metal replicas for freeze-fracture electron microscopy. 
  • Preparative techniques for freezing and freeze-sectioning macrophages for energy dispersive x-ray microanalysis. 
  • Reduced antigenicity of formaldehyde-fixed arterial allografts and their potential clinical application. 
  • Short-term effects of formaldehyde on peak expiratory flow and irritant symptoms. 
  • Simple fixation and storage protocol for preserving the internal structure of intact human donor lenses and extracted human nuclear cataract specimens. 
  • Some fixation reagents reduce or abolish the detectability of Ia-antigen and HLA-DR on cells. 
  • Storing paraformaldehyde-fixed whole blood patient samples after chronic platelet glycoprotein IIb/IIIa blockade: core laboratory considerations. 
  • TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor. 
  • X-ray diffraction and electron microscopy from Lethocerus flight muscle partially relaxed by adenylylimidodiphosphate and ethylene glycol. 
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  Keywords of People

  • McLendon, Roger Edwin, Professor of Pathology, Pathology