Flame Retardants

• 

  Subject Areas on Research

  • In Vitro Metabolism of Isopropylated and tert -Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions. 
  • A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women. 
  • Accumulation and DNA damage in fathead minnows (Pimephales promelas) exposed to 2 brominated flame-retardant mixtures, Firemaster 550 and Firemaster BZ-54. 
  • Accumulation and debromination of decabromodiphenyl ether (BDE-209) in juvenile fathead minnows (Pimephales promelas) induces thyroid disruption and liver alterations. 
  • Accumulation and endocrine disrupting effects of the flame retardant mixture Firemaster® 550 in rats: an exploratory assessment. 
  • Acetate promotes microbial reductive debromination of tetrabromobisphenol A during the startup phase of anaerobic wastewater sludge bioreactors. 
  • Acute and developmental behavioral effects of flame retardants and related chemicals in zebrafish. 
  • Alternate and new brominated flame retardants detected in U.S. house dust. 
  • Analysis of the flame retardant metabolites bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and diphenyl phosphate (DPP) in urine using liquid chromatography-tandem mass spectrometry. 
  • Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor. 
  • Assess flame retardants with care-Response. 
  • Associations between PBDEs in office air, dust, and surface wipes. 
  • Associations between Polybrominated Diphenyl Ether (PBDE) Flame Retardants, Phenolic Metabolites, and Thyroid Hormones during Pregnancy 
  • Associations between brominated flame retardants in house dust and hormone levels in men. 
  • Associations between flame retardant applications in furniture foam, house dust levels, and residents' serum levels. 
  • Associations between serum levels of Polybrominated Diphenyl Ether (PBDE) flame retardants and environmental and behavioral factors in pregnant women. 
  • Associations between urinary diphenyl phosphate and thyroid function. 
  • BDE 49 and developmental toxicity in zebrafish. 
  • Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers. 
  • Brominated and chlorinated flame retardants in San Francisco Bay sediments and wildlife. 
  • Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells. 
  • Brominated flame retardants and legacy organochlorines in archived human placenta samples: Sex differences, temporal analysis and associations with infant birth weight. 
  • Brominated flame retardants in breast milk and behavioural and cognitive development at 36 months. 
  • Brominated flame retardants in placental tissues: associations with infant sex and thyroid hormone endpoints. 
  • Characterization of Individual Isopropylated and tert-Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585. 
  • Characterization of adipogenic, PPARγ, and TRβ activities in house dust extracts and their associations with organic contaminants. 
  • Characterizing Flame Retardant Applications and Potential Human Exposure in Backpacking Tents. 
  • Characterizing firefighter's exposure to over 130 SVOCs using silicone wristbands: A pilot study comparing on-duty and off-duty exposures. 
  • Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp. 
  • Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust. 
  • Chemical Mixtures Isolated from House Dust Disrupt Thyroid Receptor β Signaling. 
  • Chemical contaminant exposures assessed using silicone wristbands among occupants in office buildings in the USA, UK, China, and India. 
  • Children's residential exposure to organophosphate ester flame retardants and plasticizers: Investigating exposure pathways in the TESIE study. 
  • Children's sleepwear: relaxation of the Consumer Product Safety Commission's flammability standards. 
  • Comment on "Mutagenic Azo Dyes, Rather Than Flame Retardants, Are the Predominant Brominated Compounds in House Dust". 
  • Comparing the Use of Silicone Wristbands, Hand Wipes, And Dust to Evaluate Children's Exposure to Flame Retardants and Plasticizers. 
  • Current-use flame retardants: Maternal exposure and neurodevelopment in children of the CHAMACOS cohort. 
  • Debromination of the flame retardant decabromodiphenyl ether by juvenile carp (Cyprinus carpio) following dietary exposure. 
  • Demographic and dietary risk factors in relation to urinary metabolites of organophosphate flame retardants in toddlers. 
  • Dermal uptake and percutaneous penetration of organophosphate esters in a human skin ex vivo model. 
  • Detection of organophosphate flame retardants in furniture foam and U.S. house dust. 
  • Determination of glucuronide conjugates of hydroxyl triphenyl phosphate (OH-TPHP) metabolites in human urine and its use as a biomarker of TPHP exposure. 
  • Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum. 
  • Developmental Exposure to Low Concentrations of Organophosphate Flame Retardants Causes Life-Long Behavioral Alterations in Zebrafish. 
  • Developmental exposure to an organophosphate flame retardant alters later behavioral responses to dopamine antagonism in zebrafish larvae. 
  • Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish. 
  • Developmental exposure to organophosphate flame retardants causes behavioral effects in larval and adult zebrafish. 
  • Developmental exposure to organophosphate flame retardants elicits overt toxicity and alters behavior in early life stage zebrafish (Danio rerio). 
  • Developmental exposure to the flame retardant, triphenyl phosphate, causes long-lasting neurobehavioral and neurochemical dysfunction. 
  • Differential exposure to organophosphate flame retardants in mother-child pairs. 
  • Diphenyl Phosphate-Induced Toxicity During Embryonic Development. 
  • Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos. 
  • Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. 
  • Do flame retardant chemicals increase the risk for thyroid dysregulation and cancer? 
  • Early zebrafish embryogenesis is susceptible to developmental TDCPP exposure. 
  • Editor's Highlight: Transplacental and Lactational Transfer of Firemaster® 550 Components in Dosed Wistar Rats. 
  • Effects of Prenatal Exposure to a Mixture of Organophosphate Flame Retardants on Placental Gene Expression and Serotonergic Innervation in the Fetal Rat Brain. 
  • Establishment of baseline cytology metrics in nestling American kestrels (Falco sparverius): Immunomodulatory effects of the flame retardant isopropylated triarylphosphate isomers. 
  • Evaluating the Use of Silicone Wristbands To Measure Personal Exposure to Brominated Flame Retardants. 
  • Evaluating the bioaccessibility of flame retardants in house dust using an in vitro Tenax bead-assisted sorptive physiologically based method. 
  • Exposure to PBDEs in the office environment: evaluating the relationships between dust, handwipes, and serum. 
  • Exposure to flame retardant chemicals and occurrence and severity of papillary thyroid cancer: A case-control study. 
  • Exposure to flame retardant chemicals on commercial airplanes. 
  • Exposure to organophosphate flame retardants in spray polyurethane foam applicators: Role of dermal exposure. 
  • Exposures, mechanisms, and impacts of endocrine-active flame retardants. 
  • Fate of flame retardants and the antimicrobial agent triclosan in planted and unplanted biosolid-amended soils. 
  • Flame retardant associations between children's handwipes and house dust. 
  • Flame retardant exposure among collegiate United States gymnasts. 
  • Flame retardant exposure assessment: findings from a behavioral intervention study. 
  • Flame retardants and their metabolites in the homes and urine of pregnant women residing in California (the CHAMACOS cohort). 
  • Gene transcription, metabolite and lipid profiling in eco-indicator daphnia magna indicate diverse mechanisms of toxicity by legacy and emerging flame-retardants. 
  • High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products. 
  • House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. 
  • Hypospadias and halogenated organic pollutant levels in maternal mid-pregnancy serum samples. 
  • Identification of flame retardants in polyurethane foam collected from baby products. 
  • Impacts of Unregulated Novel Brominated Flame Retardants on Human Liver Thyroid Deiodination and Sulfotransferation. 
  • In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components. 
  • In vitro metabolism of the brominated flame retardants 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (TBPH) in human and rat tissues. 
  • Increased coiling frequency linked to apoptosis in the brain and altered thyroid signaling in zebrafish embryos (Danio rerio) exposed to the PBDE metabolite 6-OH-BDE-47. 
  • Infants' diminished response to DTaP vaccine is associated with exposure to organophosphate esters. 
  • Influence of storage vial material on measurement of organophosphate flame retardant metabolites in urine. 
  • Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics. 
  • Intervention to reduce gymnast exposure to flame retardants from pit foam: A case study. 
  • Investigating a novel flame retardant known as V6: measurements in baby products, house dust, and car dust. 
  • Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. 
  • Lactational exposure to polybrominated diphenyl ethers and its relation to social and emotional development among toddlers. 
  • Levels of Urinary Metabolites of Organophosphate Flame Retardants, TDCIPP, and TPHP, in Pregnant Women in Shanghai. 
  • Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro. 
  • Linking PBDEs in house dust to consumer products using X-ray fluorescence. 
  • Longer commutes are associated with increased human exposure to tris(1,3-dichloro-2-propyl) phosphate. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Measurement of flame retardants and triclosan in municipal sewage sludge and biosolids. 
  • Measurement of polybrominated diphenyl ethers on hand wipes: estimating exposure from hand-to-mouth contact. 
  • Measuring Personal Exposure to Organophosphate Flame Retardants Using Silicone Wristbands and Hand Wipes. 
  • Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers. 
  • Monitoring indoor exposure to organophosphate flame retardants: hand wipes and house dust. 
  • Neurotoxicity of FireMaster 550® in zebrafish (Danio rerio): Chronic developmental and acute adolescent exposures. 
  • Novel and high volume use flame retardants in US couches reflective of the 2005 PentaBDE phase out. 
  • Occurrence of contaminants of emerging concern in mussels (Mytilus spp.) along the California coast and the influence of land use, storm water discharge, and treated wastewater effluent. 
  • Organophosphate Esters: Are These Flame Retardants and Plasticizers Affecting Children's Health? 
  • Organophosphate flame-retardant metabolite concentrations and pregnancy loss among women conceiving with assisted reproductive technology. 
  • Partial dust removal in vehicles does not mitigate human exposure to organophosphate esters. 
  • Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization. 
  • Perinatal exposure to FireMaster® 550 (FM550), brominated or organophosphate flame retardants produces sex and compound specific effects on adult Wistar rat socioemotional behavior. 
  • Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71. 
  • Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior. 
  • Polybrominated diphenyl ether flame retardants in the North American environment. 
  • Predictors and reproducibility of urinary organophosphate ester metabolite concentrations during pregnancy and associations with birth outcomes in an urban population. 
  • Predictors of tris(1,3-dichloro-2-propyl) phosphate metabolite in the urine of office workers. 
  • Predictors of urinary flame retardant concentration among pregnant women. 
  • Pregnancy exposure to organophosphate esters and the risk of attention-deficit hyperactivity disorder in the Norwegian mother, father and child cohort study. 
  • Prenatal exposure to organophosphate esters and cognitive development in young children in the Pregnancy, Infection, and Nutrition Study. 
  • Regional comparison of organophosphate flame retardant (PFR) urinary metabolites and tetrabromobenzoic acid (TBBA) in mother-toddler pairs from California and New Jersey. 
  • Reproductive outcomes associated with flame retardants among couples seeking fertility treatment: A paternal perspective. 
  • Results from Screening Polyurethane Foam Based Consumer Products for Flame Retardant Chemicals: Assessing Impacts on the Change in the Furniture Flammability Standards. 
  • Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dust. 
  • Serum levels of polybrominated diphenyl ethers (PBDEs) in foam recyclers and carpet installers working in the United States. 
  • Sex Specific Placental Accumulation and Behavioral Effects of Developmental Firemaster 550 Exposure in Wistar Rats. 
  • Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture. 
  • Sex-specific effects of perinatal FireMaster® 550 (FM 550) exposure on socioemotional behavior in prairie voles. 
  • Species specific differences in the in vitro metabolism of the flame retardant mixture, Firemaster® BZ-54. 
  • Species-specific differences and structure-activity relationships in the debromination of PBDE congeners in three fish species. 
  • The association between urinary concentrations of phosphorous-containing flame retardant metabolites and semen parameters among men from a fertility clinic. 
  • The association of urinary phosphorous-containing flame retardant metabolites and self-reported personal care and household product use among couples seeking fertility treatment. 
  • Thyroid Receptor Antagonism of Chemicals Extracted from Personal Silicone Wristbands within a Papillary Thyroid Cancer Pilot Study. 
  • Toddler's behavior and its impacts on exposure to polybrominated diphenyl ethers. 
  • Toward fire safety without chemical risk. 
  • Towards establishing indicative values for metabolites of organophosphate ester contaminants in human urine. 
  • Tris(1,3-dichloro-2-propyl)phosphate Induces Genome-Wide Hypomethylation within Early Zebrafish Embryos. 
  • Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization. 
  • Urinary biomarkers of flame retardant exposure among collegiate U.S. gymnasts. 
  • Urinary metabolites of organophosphate flame retardants and their variability in pregnant women. 
  • Urinary metabolites of organophosphate flame retardants: temporal variability and correlations with house dust concentrations. 
  • Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550. 
  • Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. 
  • Young infants' exposure to organophosphate esters: Breast milk as a potential source of exposure. 
• 

  Keywords of People

  • Ferguson, P. Lee, Associate Professor of Civil and Environmental Engineering, Civil and Environmental Engineering