Fluorescent Dyes

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  Subject Areas on Research

  • 7-Nitrobenz-2-oxa-1,3-diazole (NBD)--phallacidin: synthesis of a fluorescent actin probe. 
  • A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy in Vivo. 
  • A One-Step Staining Protocol for In-Gel Fluorescent Visualization of Proteins. 
  • A centrifugal fluidic immunoassay for ocular diagnostics with an enzymatically hydrolyzed fluorogenic substrate. 
  • A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2. 
  • A fluorescent PEBBLE nanosensor for intracellular free zinc. 
  • A fluorescent assay for agonist-activated phospholipase D in mammalian cell extracts. 
  • A galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes. 
  • A genetically encoded ratiometric indicator for chloride: capturing chloride transients in cultured hippocampal neurons. 
  • A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension. 
  • A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer. 
  • A novel imaging system permits real-time in vivo tumor bed assessment after resection of naturally occurring sarcomas in dogs. 
  • A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting. 
  • ACAP1 promotes endocytic recycling by recognizing recycling sorting signals. 
  • Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor. 
  • Ablation of the secondary heart field leads to tetralogy of Fallot and pulmonary atresia. 
  • Aldosterone Exposure Causes Increased Retinal Edema and Severe Retinopathy Following Laser-Induced Retinal Vein Occlusion in Mice. 
  • Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture. 
  • Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes. 
  • Alveolar barrier function assessed by hydrophobic and hydrophilic fluorescent solutes in rabbit lung. 
  • Aminonaphthalenesulfonamides, a new class of modifiable fluorescent detecting groups and their use in substrates for serine protease enzymes. 
  • An artery-specific fluorescent dye for studying neurovascular coupling. 
  • An assay for human chorionic gonadotrophin using the capillary fill immunosensor. 
  • An electron-microscopic study of a physiologically identified motoneurone in the leech C.N.S. after injection of the fluorescent dye Procion yellow. 
  • An enzymatically-sensitized sequential and concentric energy transfer relay self-assembled around semiconductor quantum dots. 
  • An in vivo look at vertebrate liver architecture: three-dimensional reconstructions from medaka (Oryzias latipes). 
  • Analysis of deoxyribonucleic acid replication in human X chromosomes by fluorescence microscopy. 
  • Analysis of oxygen transport in a diffusion-limited model of engineered heart tissue. 
  • Anaphylaxis following intravenous fluorescein angiography in a vitreoretinal clinic: report of 4 cases. 
  • Anatomical and physiological localization of prelabeled grafts in rat hippocampus. 
  • Application of total internal reflection fluorescence microscopy to study cell adhesion to biomaterials. 
  • Applications of nanotechnology to biotechnology commentary. 
  • Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells. 
  • Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. 
  • Asymmetrical electrically induced injury of rabbit ventricular myocytes. 
  • Atomic force and total internal reflection fluorescence microscopy for the study of force transmission in endothelial cells. 
  • Bacterial surface association of heat-labile enterotoxin through lipopolysaccharide after secretion via the general secretory pathway. 
  • Barnacle Balanus amphitrite adheres by a stepwise cementing process. 
  • Barnacle biology before, during and after settlement and metamorphosis: a study of the interface. 
  • BrdU-33258 Hoechst analysis of DNA replication in human lymphocytes with supernumerary or structurally abnormal X chromosomes. 
  • Broad spectral domain fluorescence wavelength modulation of visible and near-infrared emissive polymersomes. 
  • Capture and visualization of hydrogen sulfide by a fluorescent probe. 
  • Cell permeable fluorescent receptor for detection of H2PO4(-) in aqueous solvent. 
  • Cell-Specific Chemical Delivery Using a Selective Nitroreductase-Nitroaryl Pair. 
  • Characterization of formulation parameters affecting low molecular weight drug release from in situ forming drug delivery systems. 
  • Cholecystokinin cells purified by fluorescence-activated cell sorting respond to monitor peptide with an increase in intracellular calcium. 
  • Collateral projections of predorsal bundle cells of the superior colliculus in the rat. 
  • Colorimetric Detection of Staphylococcus aureus Contaminated Solutions without Purification. 
  • Comparative assessment of fluorescent proteins for in vivo imaging in an animal model system. 
  • Comparison of multiple enzyme activatable near-infrared fluorescent molecular probes for detection and quantification of inflammation in murine colitis models. 
  • Comparison of topical dry eye medications for the treatment of keratoconjunctivitis sicca in a botulinum toxin B-induced mouse model. 
  • Confocal imaging of intracellular chloride in living brain slices: measurement of GABAA receptor activity. 
  • Conformational changes at the carboxyl terminus of Galpha occur during G protein activation. 
  • Construction of a fluorescent biosensor family. 
  • Cooperative effect of tumor necrosis factor and gamma-interferon on chemotactic peptide receptor expression and stimulus-induced actin polymerization in HL-60 cells. 
  • Cortical imaging: capturing the moment. 
  • Cytosolic Ca2+ gradients triggering unidirectional fluid secretion from exocrine pancreas. 
  • Cytosolic delivery of macromolecules 4. Head group-dependent membrane permeabilization by pH-sensitive detergents. 
  • Cytosolic delivery of macromolecules. II. Mechanistic studies with pH-sensitive morpholine lipids. 
  • Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window. 
  • Deep-tissue photoacoustic tomography of a genetically encoded near-infrared fluorescent probe. 
  • Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. 
  • Delivery rate affects uptake of a fluorescent glucose analog in murine metastatic breast cancer. 
  • Delivery-corrected imaging of fluorescently-labeled glucose reveals distinct metabolic phenotypes in murine breast cancer. 
  • Descending auditory pathways: projections from the inferior colliculus contact superior olivary cells that project bilaterally to the cochlear nuclei. 
  • Detection of single enzymatic events in rare or single cells using microfluidics. 
  • Determination of total folate in plant material by chemical conversion into para-aminobenzoic acid followed by high performance liquid chromatography combined with on-line postcolumn derivatization and fluorescence detection. 
  • Development of a fluorescent ligand-binding assay using the AcroWell filter plate. 
  • Development of a modified positive selection medium that allows to isolate Aspergillus oryzae strains cured of the integrated niaD-based plasmid. 
  • Development of a new capillary electrophoresis-based fibre optic sensor. 
  • Development of direct GABAergic projections from the zona incerta to the somatosensory cortex of the rat. 
  • Development of long-distance efferent projections from fetal hippocampal grafts depends upon pathway specificity and graft location in kainate-lesioned adult hippocampus. 
  • Differential and simultaneous adenosine di- and triphosphate binding by MutS. 
  • Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus. 
  • Differential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sites. 
  • Differential staining of actin in metaphase spindles with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin and fluorescent DNase: is actin involved in chromosomal movement? 
  • Diffusion of low density lipoprotein-receptor complex on human fibroblasts. 
  • Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization. 
  • Direct in vivo measurement of targeted binding in a human tumor xenograft. 
  • Discovery of a fluorescent probe with HDAC6 selective inhibition. 
  • Disruption of wave-associated Rac GTPase-activating protein (Wrp) leads to abnormal adult neural progenitor migration associated with hydrocephalus. 
  • Distribution of functional glutamate and GABA receptors on hippocampal pyramidal cells and interneurons. 
  • Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways. 
  • Double-labeling of saphenous nerve neuron pools: a model for determining the accuracy of axon regeneration at the single neuron level. 
  • Doxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer. 
  • Dual energy converting nano-phosphors: upconversion luminescence and X-ray excited scintillation from a single composition of lanthanide-doped yttrium oxide. 
  • Dual-wavelength ratiometric fluorescence measurement of the membrane dipole potential. 
  • Dye-coupling in three-dimensional histoculture of rat lingual frenulum. 
  • Early experience with fluorescent angiography in free-tissue transfer reconstruction. 
  • Early wound healing exhibits cytokine surge without evidence of hypoxia. 
  • Effect of AQP1 expression level on Co(2) permeability in bovine corneal endothelium. 
  • Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation. 
  • Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling. 
  • Effect of monosaccharide composition, glycosidic linkage position and anomericity on the electrophoretic mobility of labeled oligosaccharides. 
  • Electric field-mediated transport of plasmid DNA in tumor interstitium in vivo. 
  • Elevated intracellular calcium levels in cerebellar granule neurons of weaver mice. 
  • Encoded multichromophore response for simultaneous label-free detection. 
  • Energy transfer assays of rat renal cortical endosomal fusion: evidence for superfusion. 
  • Engineered chimeric streptavidin tetramers as novel tools for bioseparations and drug delivery. 
  • Engineered nanomaterials for biophotonics applications: improving sensing, imaging, and therapeutics. 
  • Engineering the tissue which encapsulates subcutaneous implants. III. Effective tissue response times. 
  • Enhanced Sensitivity for Detection of HIV-1 p24 Antigen by a Novel Nuclease-Linked Fluorescence Oligonucleotide Assay. 
  • Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition. 
  • Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET. 
  • Evaluation of a method for counting absolute numbers of cells with a flow cytometer. 
  • Evolutionary modification of cell lineage in the direct-developing sea urchin Heliocidaris erythrogramma. 
  • Ex Vivo Tracer Efficacy in Optical Imaging of Staphylococcus Aureus Nuclease Activity. 
  • Ex Vivo and In Vivo Noninvasive Imaging of Epidermal Growth Factor Receptor Inhibition on Colon Tumorigenesis Using Activatable Near-Infrared Fluorescent Probes. 
  • Excimer laser effects on outflow facility and outflow pathway morphology. 
  • Facile separation and determination of Aconitine alkaloids in traditional Chinese medicines by CE with tris(2,2'-bipyridyl) ruthenium(II)-based electrochemiluminescence detection. 
  • Faithful expression of GFP from the PLCbeta2 promoter in a functional class of taste receptor cells. 
  • Feasibility of laser targeted photo-occlusion of ocular vessels. 
  • Feasibility of laser-targeted photoocclusion of the choriocapillary layer in rats. 
  • Features of programmed cell death in intact Xenopus oocytes and early embryos revealed by near-infrared fluorescence and real-time monitoring. 
  • Finite element modeling predictions of region-specific cell-matrix mechanics in the meniscus. 
  • Flow cytometric analysis of DNA content in budding yeast. 
  • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. 
  • Fluorescein Angiographic Characteristics of Macular Edema During Infancy. 
  • Fluorescence imaging of GABAA receptor-mediated intracellular [Cl-] in P19-N cells reveals unique pharmacological properties. 
  • Fluorescence imaging of changes in intracellular chloride in living brain slices. 
  • Fluorescence studies of chicken liver fatty acid synthase. Segmental flexibility and distance measurements. 
  • Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes. 
  • Fluorescent labeling of dissociated fetal cells for tissue culture. 
  • Fluorescent low density lipoprotein for observation of dynamics of individual receptor complexes on cultured human fibroblasts. 
  • Fluorescent peptide displacement as a general assay for screening small molecule libraries against RNA. 
  • Fluorescent probes as a measure of conformational alterations induced by nucleophilic modification and proteolysis of bovine alpha 2-macroglobulin. 
  • Fluorescent probes as indicators of conformation changes in transducin on activation. 
  • Fluorescent probes that stain living nerve terminals. 
  • Fluorescent properties of pyrene bound at specific acylation sites of chicken liver fatty acid synthase. 
  • Fluorescent viability stains overestimate chondrocyte viability in osteoarticular allografts. 
  • Focal delivery of neurotrophins into the central nervous system using fluorescent latex microspheres. 
  • Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes. 
  • Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration. 
  • Forward scatter pulse width signals resolve multiple populations of endosomes. 
  • Functional evaluation of nonphagocytic NAD(P)H oxidases. 
  • Functional photoacoustic microscopy of pH. 
  • Functional reentry in cultured monolayers of neonatal rat cardiac cells. 
  • Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA. 
  • Gadolinium chloride alters the acinar distribution of phagocytosis and balance between pro- and anti-inflammatory cytokines. 
  • Gene silencing using RNA interference in embryonic stem cells. 
  • Genetic immunization with LYVE-1 cDNA yields function-blocking antibodies against native protein. 
  • Genome mapping by fluorescent fingerprinting. 
  • Gentamicin inhibits rat renal cortical homotypic endosomal fusion: role of megalin. 
  • Green fluorescent latex microspheres: a new retrograde tracer. 
  • Green fluorescent protein as a tag for molecular motor proteins. 
  • Hand-held spectroscopic device for in vivo and intraoperative tumor detection: contrast enhancement, detection sensitivity, and tissue penetration. 
  • Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients. 
  • Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8. 
  • High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor. 
  • Hoechst dye efflux reveals a novel CD7(+)CD34(-) lymphoid progenitor in human umbilical cord blood. 
  • Hyperosmotically induced volume change and calcium signaling in intervertebral disk cells: the role of the actin cytoskeleton. 
  • Hyperspectral imaging system using acousto-optic tunable filter for flow cytometry applications. 
  • Identification of fluorescent beads using a coded aperture snapshot spectral imager. 
  • Identification of viral infection by confocal microscopy. 
  • Identifying potential tumor markers and antigens by database mining and rapid expression screening. 
  • Imaging molecular pathways: reporter genes. 
  • Imaging primary mouse sarcomas after radiation therapy using cathepsin-activatable fluorescent imaging agents. 
  • Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy. 
  • Improved flow cytometric analysis of the budding yeast cell cycle. 
  • Improved methods and standards for telomerase detection: quantitative histopathology using antibody staining. 
  • In vivo analysis of white adipose tissue in zebrafish. 
  • In vivo fluorescence imaging: a personal perspective. 
  • In vivo imaging of epileptic activity using 2-NBDG, a fluorescent deoxyglucose analog. 
  • In vivo optical molecular imaging and analysis in mice using dorsal window chamber models applied to hypoxia, vasculature and fluorescent reporters. 
  • Indocyanine green-loaded nanoparticles for image-guided tumor surgery. 
  • Influence of lipid composition on physical properties and peg-mediated fusion of curved and uncurved model membrane vesicles: "nature's own" fusogenic lipid bilayer. 
  • Interaction of dihydrofolate reductase with methotrexate: ensemble and single-molecule kinetics. 
  • Intraglandular injection of botulinum toxin a reduces tear production in rabbits. 
  • Intraoperative detection and removal of microscopic residual sarcoma using wide-field imaging. 
  • Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH. 
  • Investigation of acoustic streaming patterns around oscillating sharp edges. 
  • Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles. 
  • Ionic liquid-assisted PDMS microchannel modification for efficiently resolving fluorescent dye and protein adsorption. 
  • Is There a Right Way to Interpret SPY? Normalization of Indocyanine Green Angiography Readings in a Burn Model. 
  • Kinetic and structural investigation of acyl-binding sites on avian fatty acid synthase. 
  • Laser-assisted indocyanine green dye angiography accurately predicts the split-thickness graft timing of integra artificial dermis. 
  • Latex nanosphere delivery system (LNDS): novel nanometer-sized carriers of fluorescent dyes and active agents selectively target neuronal subpopulations via uptake and retrograde transport. 
  • Lectin as a marker for staining and purification of embryonic pancreatic epithelium. 
  • Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens. 
  • Ligand interactions in the adenosine nucleotide-binding domain of the Hsp90 chaperone, GRP94. II. Ligand-mediated activation of GRP94 molecular chaperone and peptide binding activity. 
  • Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis. 
  • Localization of cortical granule constituents before and after exocytosis in the hamster egg. 
  • Measurement of Reactive Oxygen Species by Fluorescent Probes in Pancreatic Cancer Cells. 
  • Measurement of chloride movement in neuronal preparations. 
  • Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics 
  • Mechanism and specificity of lanthanide series cation transport by ionophores A23187, 4-BrA23187, and ionomycin. 
  • Melanoma, a tumor based on a mutant stem cell? 
  • Membrane-protein structural mapping of chloroplast coupling factor in asolectin vesicles. 
  • Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. 
  • Microbial biofilms in the gut: visualization by electron microscopy and by acridine orange staining. 
  • Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation. 
  • Microfluidic preparation of polymer-nucleic acid nanocomplexes improves nonviral gene transfer. 
  • Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice. 
  • Mitochondrial and intrinsic optical signals imaged during hypoxia and spreading depression in rat hippocampal slices. 
  • Modulation of intracellular Ca++ in cultured astrocytes by influx through voltage-activated Ca++ channels. 
  • Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth. 
  • Modulation of poly(ethylene glycol)-induced fusion by membrane hydration: importance of interbilayer separation. 
  • Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions. 
  • Molecular imaging of gastric neoplasia with near-infrared fluorescent activatable probes. 
  • Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II. 
  • Molecular phenotype of airway side population cells. 
  • Monitoring β-secretase activity in living cells with a membrane-anchored FRET probe. 
  • Multiplexed 3D FRET imaging in deep tissue of live embryos. 
  • NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection. 
  • Native fluorescence and mag-indo-1-protein interaction as tools for probing unfolding and refolding sequences of the bovine serum albumin subdomain in the presence of guanidine hydrochloride. 
  • Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial. 
  • Near-infrared fluorescence imaging of HER-2 protein over-expression in tumour cells. 
  • Near-infrared optical imaging of B16 melanoma cells via low-density lipoprotein-mediated uptake and delivery of high emission dipole strength tris[(porphinato)zinc(II)] fluorophores. 
  • Near-infrared optical imaging of integrin alphavbeta3 in human tumor xenografts. 
  • Neonatal whisker removal in rats stabilizes a transient projection from the auditory thalamus to the primary somatosensory cortex. 
  • Nerve terminal remodeling visualized in living mice by repeated examination of the same neuron. 
  • Neurite outgrowth is enhanced by anti-idiotypic monoclonal antibodies to the ganglioside GM1. 
  • Neuron/glia relationships observed over intervals of several months in living mice. 
  • Non invasive high resolution in vivo imaging of alpha-naphthylisothiocyanate (ANIT) induced hepatobiliary toxicity in STII medaka. 
  • Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe. 
  • Noninvasive visualization of blood flow in the choriocapillaris of the rat. 
  • Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity. 
  • Nuclear responses to depletion of mitochondrial DNA in human cells. 
  • Okadaic acid disrupts synaptic vesicle trafficking in a ribbon-type synapse. 
  • Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio). 
  • Optical imaging of cervical pre-cancers with structured illumination: an integrated approach. 
  • Optical imaging of hippocampal neurons with a chloride-sensitive dye: early effects of in vitro ischemia. 
  • Optical imaging of intracellular chloride in living brain slices. 
  • Optical imaging of living brain slices. 
  • Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress. 
  • Optical measurements of transmembrane potential changes during electric field stimulation of ventricular cells. 
  • Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay. 
  • Organization of the inferior colliculus of the gerbil (Meriones unguiculatus): differences in distribution of projections from the cochlear nuclei and the superior olivary complex. 
  • Organization of the superior olivary complex in the guinea pig: II. Patterns of projection from the periolivary nuclei to the inferior colliculus. 
  • Orientation of LamB signal peptides in bilayers: influence of lipid probes on peptide binding and interpretation of fluorescence quenching data. 
  • Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation. 
  • Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse. 
  • Patterns of excitation and inhibition evoked by horizontal connections in visual cortex share a common relationship to orientation columns. 
  • Peptide-Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite-Mediated Nitration. 
  • Performance comparison between the high-speed Yokogawa spinning disc confocal system and single-point scanning confocal systems. 
  • Permeability properties of the mammalian bladder apical membrane. 
  • Photoreceptor phosphodiesterase: interaction of inhibitory gamma subunit and cyclic GMP with specific binding sites on catalytic subunits. 
  • Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration. 
  • Potentiation of calcium levels by extracellular arachidonic acid in nuclei isolated from macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin. 
  • Preferential extravasation and accumulation of liposomal vincristine in tumor comparing to normal tissue enhances antitumor activity. 
  • Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses. 
  • Presynaptic calcium signals during neurotransmitter release: detection with fluorescent indicators and other calcium chelators. 
  • Primary treatment of nasolacrimal duct obstruction with balloon catheter dilation in children younger than 4 years of age. 
  • Primary treatment of nasolacrimal duct obstruction with nasolacrimal duct intubation in children younger than 4 years of age. 
  • Probing bacterial gene expression within host cells. 
  • Probing the iron pool. Focus on "Detection of intracellular iron by its regulatory effect". 
  • Progressive incorporation of propidium iodide in cultured mouse neurons correlates with declining electrophysiological status: a fluorescence scale of membrane integrity. 
  • Projections from the ventral cochlear nucleus to the inferior colliculus and the contralateral cochlear nucleus in guinea pigs. 
  • Protease-activated quantum dot probes. 
  • Protein-protein and protein-DNA interactions at the bacteriophage T4 DNA replication fork. Characterization of a fluorescently labeled DNA polymerase sliding clamp. 
  • Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration. 
  • Quantification and time course of microvascular obstruction by contrast-enhanced echocardiography and magnetic resonance imaging following acute myocardial infarction and reperfusion. 
  • Quantitation of protein-protein interactions by thermal stability shift analysis. 
  • Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH. 
  • Quantitative and selective fluorophore labeling of phosphoserine on peptides and proteins: characterization at the attomole level by capillary electrophoresis and laser-induced fluorescence. 
  • Quantitative assessment of fibrinogen cross-linking by epsilon aminocaproic acid in patients with end-stage liver disease. 
  • Quantitative surface-enhanced resonant Raman scattering multiplexing of biocompatible gold nanostars for in vitro and ex vivo detection. 
  • Reaction based fluorescent probes for hydrogen sulfide. 
  • Real-time detection of circulating apoptotic cells by in vivo flow cytometry. 
  • Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. 
  • Receptor-recognized alpha 2-macroglobulin-methylamine elevates intracellular calcium, inositol phosphates and cyclic AMP in murine peritoneal macrophages. 
  • Redox changes of cultured endothelial cells and actin dynamics. 
  • Regression of atherosclerosis in monkeys reduces vascular superoxide levels. 
  • Regulation of neurotransmitter release by synapsin III. 
  • Reinnervation accuracy of the rat femoral nerve by motor and sensory neurons. 
  • Reinnervation of Müller's smooth muscle by atypical sympathetic pathways following neonatal ganglionectomy in the rat: structural and functional investigations of enhanced neuroplasticity. 
  • Relationship of T2-Weighted MRI Myocardial Hyperintensity and the Ischemic Area-At-Risk. 
  • Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro. 
  • Replicating circular DNA molecules in yeast. 
  • Reprogramming after chromosome transfer into mouse blastomeres. 
  • Robust and efficient synthetic method for forming DNA microarrays. 
  • Robust approaches to quantitative ratiometric FRET imaging of CFP/YFP fluorophores under confocal microscopy. 
  • SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. 
  • SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin. 
  • Schwan equation and transmembrane potential induced by alternating electric field. 
  • Selective visualization of choroidal neovascular membranes. 
  • Sensing membrane stress with near IR-emissive porphyrins. 
  • Sensing the impact of environment on small molecule differentiation of RNA sequences. 
  • Sensitive analysis of [D-Pen2,5]enkephalin in rat serum by capillary electrophoresis and laser-induced fluorescence detection. 
  • Sensitive, label-free protein assay using 1-ethyl-3-methylimidazolium tetrafluoroborate-supported microchip electrophoresis with laser-induced fluorescence detection. 
  • Sensitivity enhancement of optical immunosensors by the use of a surface plasmon resonance fluoroimmunoassay. 
  • Sertoli cells of the mouse testis originate from the coelomic epithelium. 
  • Signal-on Protein Detection via Dye Translocation between Aptamer and Quantum Dot. 
  • Silica-coated gold nanostars for combined surface-enhanced Raman scattering (SERS) detection and singlet-oxygen generation: a potential nanoplatform for theranostics. 
  • Simultaneous measurement of liposome extravasation and content release in tumors. 
  • Simultaneous optical recording of evoked and spontaneous transients of membrane potential and intracellular calcium concentration with high spatio-temporal resolution. 
  • Simultaneous optical recording of membrane potential and intracellular calcium from brain slices. 
  • Single-Step Assembly of Multimodal Imaging Nanocarriers: MRI and Long-Wavelength Fluorescence Imaging. 
  • Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II. 
  • Small-volume rapid-mix device for subsecond kinetic analysis in flow cytometry. 
  • Spectral perturbations and oligomer/monomer formation in 124-kilodalton Avena phytochrome. 
  • Spectroscopic characterization of streptavidin functionalized quantum dots. 
  • Stability studies on a lipase from Bacillus subtilis in guanidinium chloride. 
  • Standing surface acoustic wave (SSAW)-based microfluidic cytometer. 
  • Static and dynamic model for 4-aminodiphenyl fluorescence quenching by carbontetrachloride in hexane. 
  • Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx. 
  • Stress fibers in endothelial cells overlying atherosclerotic lesions in rabbit aorta. 
  • Stretching fibronectin. 
  • Structural mapping of chloroplast coupling factor. 
  • Structural mapping of rabbit muscle phosphofructokinase. Distance between the adenosine cyclic 3',5'-phosphate binding site and a reactive sulfhydryl group. 
  • Structural origin of the high affinity of a chemically evolved lanthanide-binding peptide. 
  • Structural transitions accompanying the activation of peptide binding to the endoplasmic reticulum Hsp90 chaperone GRP94. 
  • Structure and interactive properties of highly fluorinated phospholipid bilayers. 
  • Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein. 
  • Structure-based engineering of environmentally sensitive fluorophores for monitoring protein-protein interactions. 
  • Studies of the ethanol-induced interdigitated gel phase in phosphatidylcholines using the fluorophore 1,6-diphenyl-1,3,5-hexatriene. 
  • Substance P dependence of endosomal fusion during bladder inflammation. 
  • Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer. 
  • Superquenching as a detector for microsphere-based flow cytometric assays. 
  • Surface recruitment but not activation of integrin alpha IIb beta 3 (GPIIb-IIIa) requires a functional actin cytoskeleton. 
  • Surface-enhanced Raman scattering for cancer diagnostics: detection of the BCL2 gene. 
  • Synaptotagmin I synchronizes transmitter release in mouse hippocampal neurons. 
  • Synchronous luminescence: a new detection technique for multiple fluorescent probes used for DNA sequencing. 
  • Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. 
  • Systematic morphological profiling of human gene and allele function via Cell Painting. 
  • Systemic toxicology and laser safety of laser targeted angiography with heat sensitive liposomes. 
  • Targeted labeling of neurons in a specific functional micro-domain of the neocortex by combining intrinsic signal and two-photon imaging. 
  • The actin cytoskeleton reorganization induced by Rac1 requires the production of superoxide. 
  • The allocation of early blastomeres to the ectoderm and endoderm is variable in the sea urchin embryo. 
  • The conformation of the active site of myosin probed using mant-nucleotides. 
  • The corneal epithelium after optisol-GS storage. 
  • The development of quantum dot calibration beads and quantitative multicolor bioassays in flow cytometry and microscopy. 
  • The distribution of synapses on a physiologically identified motor neuron in the central nervous system of the leech. An electron microscope study after the injection of the fluorescent dye procion yellow. 
  • The evaluation of complex-dependent alterations in human factor VIIa. 
  • The evolving capabilities of rhodopsin-based genetically encoded voltage indicators. 
  • The expression of plasma nucleosomes in mice undergoing in vivo apoptosis. 
  • The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics. 
  • The mechanical or metabolic function of secondary osteonal bone in the monkey Macaca fascicularis. 
  • The pallial basal ganglia pathway modulates the behaviorally driven gene expression of the motor pathway. 
  • The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors. 
  • The shape of dendritic arbors in different functional domains of the cortical orientation map. 
  • The sublaminar organization of corticogeniculate neurons in layer 6 of macaque striate cortex. 
  • The use of CE-electrochemiluminescence with ionic liquid for the determination of bioactive constituents in Chinese traditional medicine. 
  • The use of fluorometric assays to assess the immune response to DNA in murine systemic lupus erythematosus. 
  • The use of lipid microtubes as a novel slow-release delivery system for laryngeal injection. 
  • Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes. 
  • Three-dimensional image analysis of plugging at the septal pore by Woronin body during hypotonic shock inducing hyphal tip bursting in the filamentous fungus Aspergillus oryzae. 
  • Topographic and laminar organizations of the incertocortical pathway in rats. 
  • Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe. 
  • Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress. 
  • Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo. 
  • Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations. 
  • Transient opening of fibronectin type III (FNIII) domains: the interaction of the third FNIII domain of FN with anastellin. 
  • Transscleral diffusion of ethacrynic acid and sodium fluorescein. 
  • Troglitazone-induced intracellular oxidative stress in rat hepatoma cells: a flow cytometric assessment. 
  • Two embryonic, tissue-specific molecules identified by a double-label immunofluorescence technique for monoclonal antibodies. 
  • Two mechanisms that raise free intracellular calcium in rat hippocampal neurons during hypoosmotic and low NaCl treatment. 
  • Two-dimensional fluorescence intensity distribution analysis: theory and applications. 
  • Two-photon molecular excitation imaging of Ca2+ transients in Langendorff-perfused mouse hearts. 
  • Ultrafast excited-state dynamics of nanoscale near-infrared emissive polymersomes. 
  • Uptake and intracellular fate of multifunctional nanoparticles: a comparison between lipoplexes and polyplexes via quantum dot mediated Förster resonance energy transfer. 
  • Use of SYTO 13, a fluorescent dye binding nucleic acids, for the detection of microparticles in in vitro systems. 
  • Using confocal microscopy and the fluorescent indicator, 6-methoxy-N-ethylquinolinium iodide, to measure changes in intracellular chloride. 
  • Using fluorine nuclear magnetic resonance to probe changes in the structure and dynamics of membrane-active peptides interacting with lipid bilayers. 
  • Video-assisted thoracoscopic transplantation of myoblasts into the heart. 
  • Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes. 
  • Visualization of neuromuscular junctions over periods of several months in living mice. 
  • Vital imaging of glomeruli in the mouse olfactory bulb. 
  • pH-dependent conformational change of gastric mucin leads to sol-gel transition. 
  • zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. 
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  Keywords of People

  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Soderling, Scott Haydn, Professor in Cell Biology, Cell Biology
  • Turner, Dennis Alan, Professor of Neurosurgery, Biomedical Engineering
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Zhang, Zhiquan, Assistant Professor in Anesthesiology, Anesthesiology