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Subject Areas on Research
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A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer.
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A methodology for utilization of predictive genomic signatures in FFPE samples.
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Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti-RB antibodies.
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Acoustic radiation force impulse imaging of thermally- and chemically-induced lesions in soft tissues: preliminary ex vivo results.
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Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma.
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Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep.
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Active staining of mouse embryos for magnetic resonance microscopy.
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Air concentrations of VOCs in portable and traditional classrooms: results of a pilot study in Los Angeles County.
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Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer.
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Antinociceptive activity of Syzygium jambos leaves extract on rats.
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Array-based comparative genomic hybridization from formalin-fixed, paraffin-embedded breast tumors.
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Clinical studies of hemodialysis access through formaldehyde-fixed arterial allografts.
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Complement-mediated, infection-enhancing antibodies in plasma from vaccinated macaques before and after inoculation with live simian immunodeficiency virus.
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Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies.
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Concentration of lead in various endodontic filling materials.
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Consequences of chemical modifications on the free radical reactions of human hemoglobin.
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Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man.
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Development of a tracheal implant xenograft model to expose human bronchial epithelial cells to toxic gases.
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Differential Health Effects of Constant versus Intermittent Exposure to Formaldehyde in Mice: Implications for Building Ventilation Strategies.
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Dimorphic immunohistochemical staining in ocular sebaceous neoplasms: a useful diagnostic aid.
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Directed evolution of the surface chemistry of the reporter enzyme beta-glucuronidase.
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Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation.
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Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.
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Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1.
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Fluorescent Immunohistochemistry.
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Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment.
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Formaldehyde case reports.
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Formaldehyde concentrations in the blood of rhesus monkeys after inhalation exposure.
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Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems.
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Gene expression analysis of messenger RNP complexes.
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Genome-wide localization of replication factors.
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Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.
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Halogen Substitution Influences Ketamine Metabolism by Cytochrome P450 2B6: In Vitro and Computational Approaches.
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How an enzyme binds the C1 carrier tetrahydromethanopterin. Structure of the tetrahydromethanopterin-dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1.
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Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content.
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Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas.
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Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodeficiency virus in a male urethral challenge model.
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Integrative molecular profiling of routine clinical prostate cancer specimens.
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Magnetic resonance imaging of chronic myocardial infarcts in formalin-fixed human autopsy hearts.
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Molecular biologic substaging of stage I NSCLC through immunohistochemistry performed on formalin-fixed, paraffin-embedded tissue.
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Molecular subtype classification of formalin-fixed, paraffin-embedded diffuse large B-cell lymphoma samples on the ICEPlex® system.
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Mosquito coil emissions and health implications.
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Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity.
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Optical mapping of protein-DNA complexes on chromatin fibers.
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Optimization of Single- and Dual-Color Immunofluorescence Protocols for Formalin-Fixed, Paraffin-Embedded Archival Tissues.
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Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis.
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Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction.
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Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: the UNC SPORE experience. University of North Carolina Specialized Program of Research Excellence.
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Quantitative analysis of gas-phase formaldehyde molecular species at equilibrium with formalin solution.
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Reduced antigenicity of formaldehyde-fixed arterial allografts and their potential clinical application.
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Screening for pain phenotypes: analysis of three congenic mouse strains on a battery of nine nociceptive assays.
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Short-term effects of formaldehyde on peak expiratory flow and irritant symptoms.
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Simple fixation and storage protocol for preserving the internal structure of intact human donor lenses and extracted human nuclear cataract specimens.
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Social modulation of pain as evidence for empathy in mice.
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Some fixation reagents reduce or abolish the detectability of Ia-antigen and HLA-DR on cells.
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Sources of volatile organic compounds in suburban homes in Shanghai, China, and the impact of air filtration on compound concentrations
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Storing paraformaldehyde-fixed whole blood patient samples after chronic platelet glycoprotein IIb/IIIa blockade: core laboratory considerations.
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Stress-induced hyperalgesia is associated with a reduced and delayed GABA inhibitory control that enhances post-synaptic NMDA receptor activation in the spinal cord.
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TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.
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The metabolism of luteinizing hormone. Plasma clearance, urinary excretion, and tissue uptake.
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The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine.
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Topical capsaicin treatment suppresses formalin-induced fos expression in rat spinal cord.
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Validation of ovarian cancer gene expression signatures for survival and subtype in formalin fixed paraffin embedded tissues.
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[Effect of intrathecal katemine on the expression of nNOS in spinal dorsal horn in rats with formalin pain].
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[Effect of intrathecal pumping morphine on immunological function in rats with formalin pain].
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[Effect of intrathecal pumping tramadol on the immune function in rats with formalin pain].
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[Intrathecal administration of HSV-I amplicon vector-mediated HPPE gene therapy of nocicepion in rats with formalin pain].
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Keywords of People
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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Nielsen, Karen Cristina,
Associate Professor of Anesthesiology,
Anesthesiology, Ambulatory