Francisella tularensis

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  Subject Areas on Research

  • Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase. 
  • Dissection of the molecular circuitry controlling virulence in Francisella tularensis. 
  • IFN-γ, but not IL-17A, is required for survival during secondary pulmonary Francisella tularensis Live Vaccine Stain infection. 
  • Identification of early interactions between Francisella and the host. 
  • Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response. 
  • Structural and Biochemical Characterization of the Francisella tularensis Pathogenicity Regulator, Macrophage Locus Protein A (MglA). 
  • Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida. 
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  Keywords of People

  • Guan, Ziqiang, Research Professor in Biochemistry, Biochemistry