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Subject Areas on Research
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5-Oxo-eicosanoids and hematopoietic cytokines cooperate in stimulating neutrophil function and the mitogen-activated protein kinase pathway.
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A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase.
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A hot oxidant, 3-NO2Y122 radical, unmasks conformational gating in ribonucleotide reductase.
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A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.
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Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity.
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Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine.
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Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides.
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Brain resuscitation. Medical management and innovations.
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Carbon extension in peptidylnucleoside biosynthesis by radical SAM enzymes.
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Citrate and vitamin E blunt the shock wave-induced free radical surge in an in vitro cell culture model.
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Competitive apnea and its effect on the human brain: focus on the redox regulation of blood-brain barrier permeability and neuronal-parenchymal integrity.
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Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice.
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Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro.
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Consequences of chemical modifications on the free radical reactions of human hemoglobin.
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Cooperative effect of tumor necrosis factor and gamma-interferon on chemotactic peptide receptor expression and stimulus-induced actin polymerization in HL-60 cells.
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Cupric-amyloid beta peptide complex stimulates oxidation of ascorbate and generation of hydroxyl radical.
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Current status of antioxidant therapy for Alzheimer's Disease.
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Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response.
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Cyclosporine increases hepatocyte synthesis of the immunosuppressive free radical nitric oxide.
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Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1.
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Doxorubicin resistance conferred by selective enhancement of intracellular glutathione peroxidase or superoxide dismutase content in human MCF-7 breast cancer cells.
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Early AGEing and Alzheimer's.
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Environmental toxins induce intracellular responses of airway epithelium through reactive species of oxygen and nitrogen. Roger S. Mitchell Lecture.
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Equilibration of tyrosyl radicals (Y356•, Y731•, Y730•) in the radical propagation pathway of the Escherichia coli class Ia ribonucleotide reductase.
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Evidence for a radical mechanism of halogenation of monochlorodimedone catalyzed by chloroperoxidase.
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Evidence for formation of superoxide and formate radicals in Methanobacterium formicicum.
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Extracellular superoxide dismutase (EC-SOD) quenches free radicals and attenuates age-related cognitive decline: opportunities for novel drug development in aging.
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Extracellular superoxide dismutase, nitric oxide, and central nervous system O2 toxicity.
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Ferruginous bodies: implications in the mechanism of fiber and particle toxicity.
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Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions.
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Free radicals formed by exposure of pyrimidine solids to sodium atoms: an electron spin resonance study.
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Functionalized micellar assemblies prepared via block copolymers synthesized by living free radical polymerization upon peptide-loaded resins.
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Generation of hydroxyl radical by crocidolite asbestos is proportional to surface [Fe3+].
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Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice.
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Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase.
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Hemoglobin-based oxygen carriers (HBOCs): structural alterations that affect free radical generation.
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Hyperfractionated irradiation and concurrent cisplatin in brain stem tumors: a Pediatric Oncology Group pilot study (9139).
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Hyperthermic sensitization by the radical initiator 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH). I. In vitro studies.
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Hypothesis: iron chelation plays a vital role in neutrophilic inflammation.
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Identification and quantification of regioisomeric cholesteryl linoleate hydroperoxides in oxidized human low density lipoprotein and high density lipoprotein.
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In vivo assessment of free radical activity during shock wave lithotripsy using a microdialysis system: the renoprotective action of allopurinol.
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Increased survival of skin flaps by scavengers of superoxide radical.
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Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis.
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Involvement of radical species in the oxidation of aminopyrine and 4-aminoantipyrine by cumene hydroperoxide in rat liver microsomes.
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Ischemia/reperfusion injury in microvascular surgery.
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L-arginine enhances injury in the isolated rabbit lung during hyperoxia.
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Mapping of peroxyl radical induced damage on genomic DNA.
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Mechanism of Rate Acceleration of Radical C-C Bond Formation Reaction by a Radical SAM GTP 3',8-Cyclase.
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Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA.
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Mechanisms of the antioxidant effects of nitric oxide.
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Melatonin increases both life span and tumor incidence in female CBA mice.
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Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.
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Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation.
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Mitoxantrone: propensity for free radical formation and lipid peroxidation--implications for cardiotoxicity.
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Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.
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Nitrofurantoin-stimulated proteolysis in human erythrocytes: a novel index of toxic insult by nitroaromatics.
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Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash.
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Oxidant generation promotes iron sequestration in BEAS-2B cells exposed to asbestos.
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Pathways of cell signaling in hyperoxia.
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Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production.
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Pushing the boundaries of intrinsically stable radicals: inverse design using the thiadiazinyl radical as a template.
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Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules.
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Raising the bar: how HIF-1 helps determine tumor radiosensitivity.
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Regulation of gamma-aminobutyric acid/barbiturate receptor-gated chloride ion flux in brain vesicles by phospholipase A2: possible role of oxygen radicals.
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Reproduction and survival in Mediterranean fruit flies: a "protein and energy" free radical model of aging.
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Shock wave lithotripsy causes ipsilateral renal injury remote from the focal point: the role of regional vasoconstriction.
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Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation.
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Spontaneous tumor cell killing by human blood monocytes and human peritoneal macrophages: lack of alteration by endotoxin or quenchers of reactive oxygen species.
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Studies of aldehyde oxidase by electron paramagnetic resonance spectroscopy. I. Spectra at equilibrium states.
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Superoxide dismutase from Streptococcus mutans. Isolation and characterization of two forms of the enzyme.
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Superoxidized states of Escherichia coli sulfite reductase heme protein subunit.
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Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic.
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The Elusive 5'-Deoxyadenosyl Radical: Captured and Characterized by Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopies.
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The effect of xanthine/xanthine oxidase generated reactive oxygen species on synaptic transmission.
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The nitric oxide donor S-nitroso-N-acetylpenicillamine (SNAP) increases free radical generation and degrades left ventricular function after myocardial ischemia-reperfusion.
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The nitric oxide synthase inhibitor N(G)-nitro-L-arginine decreases defibrillation-induced free radical generation.
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The nitric oxide synthase inhibitor N(G)-nitro-L-arginine decreases defibrillation-induced free radical generation.
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The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes.
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The role of thermal injury on intestinal bacterial translocation and the mitigating role of probiotics: A review of animal and human studies.
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Two crystal forms of bovine superoxide dismutase.
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Ultraviolet light and free radicals: an immunologic theory of epidermal carcinogenesis.
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Urinary biomarkers of oxidative status in a clinical model of oxidative assault.
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Vitamin E treatment of tardive dyskinesia.
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[In vitro studies on antioxidant and antimicrobial activities of polysaccharide from Lycoris aurea].
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