Frontal Lobe

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  Subject Areas on Research

  • (No) time for control: Frontal theta dynamics reveal the cost of temporally guided conflict anticipation. 
  • 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner. 
  • A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure. 
  • A large-scale distributed network for covert spatial attention: further anatomical delineation based on stringent behavioural and cognitive controls. 
  • A pathway in primate brain for internal monitoring of movements. 
  • AGTR1 gene variation: association with depression and frontotemporal morphology. 
  • Abnormal fronto-limbic engagement in incarcerated stimulant users during moral processing. 
  • Abnormal functional connectivity in autism spectrum disorders during face processing. 
  • Abnormalities of the corpus callosum in nonpsychotic children with chromosome 22q11 deletion syndrome. 
  • Absence of electrographic seizures after transient forebrain ischemia in the Mongolian gerbil. 
  • Activity and functional connectivity of inferior frontal cortex associated with response conflict. 
  • Adult age differences in frontostriatal representation of prediction error but not reward outcome. 
  • Affective context interferes with cognitive control in unipolar depression: an fMRI investigation. 
  • Age mediation of frontoparietal activation during visual feature search. 
  • Age-related temporal and parietal cortical thinning in autism spectrum disorders. 
  • Altered Brain Developmental Trajectories in Adolescents After Initiating Drinking. 
  • Altered Synchronizations among Neural Networks in Geriatric Depression. 
  • Altered network connectivity predicts response to cognitive-behavioral therapy in pediatric obsessive-compulsive disorder. 
  • An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci. 
  • An unusual variant of the fronto-orbital artery. 
  • Arteriosclerotic depression. 
  • Aspirated contrast material contributing to respiratory arrest in a pediatric trauma patient. 
  • Attentive and pre-attentive aspects of figural processing. 
  • Beyond the labeled line: variation in visual reference frames from intraparietal cortex to frontal eye fields and the superior colliculus 
  • Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. 
  • Brain circuits for the internal monitoring of movements. 
  • Brain connectivity and visual attention. 
  • Brain responses in the processing of lexical pitch-accent by Japanese speakers. 
  • Brain volumes in psychotic youth with schizophrenia and mood disorders. 
  • Caspase-3 activation in rat frontal cortex following treatment with typical and atypical antipsychotics. 
  • Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype. 
  • Cerebral cortical gray matter overgrowth and functional variation of the serotonin transporter gene in autism. 
  • Characterization of bilateral frontal lobe cerebral oxygen saturation in patients with mild traumatic brain injury. 
  • Characterization of the supplementary motor area syndrome and seizure outcome after medial frontal lobe resections in pediatric epilepsy surgery. 
  • Chemopotentiation by ultrafractionated radiotherapy in glioblastoma resistant to conventional therapy. 
  • Clinicopathological characteristics and treatment of rhabdoid glioblastoma. 
  • Clonazepam-induced up-regulation of serotonin1 binding sites in frontal cortex of rat. 
  • Cocaine dependence modulates the effect of HIV infection on brain activation during intertemporal decision making. 
  • Cocaine-related alterations in fronto-parietal gray matter volume correlate with trait and behavioral impulsivity. 
  • Compensatory activation in fronto-parietal cortices among HIV-infected persons during a monetary decision-making task. 
  • Compensatory saccades made to remembered targets following orbital displacement by electrically stimulating the dorsomedial frontal cortex or frontal eye fields of primates. 
  • Complex choristoma of the gyrus rectus: a distinct clinicopathologic entity? 
  • Composition and topographic organization of signals sent from the frontal eye field to the superior colliculus. 
  • Conflict monitoring in the human anterior cingulate cortex during selective attention to global and local object features. 
  • Conical electron tomography of a chemical synapse: vesicles docked to the active zone are hemi-fused. 
  • Convulsive threshold differences in right unilateral and bilateral ECT. 
  • Corollary discharge for action and cognition 
  • Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. 
  • Cortical networks subserving pursuit and saccadic eye movements in humans: an FMRI study. 
  • Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice. 
  • Depressive state- and disease-related alterations in neural responses to affective and executive challenges in geriatric depression. 
  • Developmental increases in effective connectivity to brain regions involved in phonological processing during tasks with orthographic demands. 
  • Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment. 
  • Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding. 
  • Diffusion property and functional connectivity of superior longitudinal fasciculus underpin human metacognition. 
  • Diffusion tensor imaging studies in late-life depression: systematic review and meta-analysis. 
  • Discharge properties of MST neurons that project to the frontal pursuit area in macaque monkeys. 
  • Dissociating top-down attentional control from selective perception and action. 
  • Dissociation of event-related potentials indexing arousal and semantic cohesion during emotional word encoding. 
  • Doing without learning: stimulation of the frontal eye fields and floccular complex does not instruct motor learning in smooth pursuit eye movements. 
  • Dopaminergic behaviors and signal transduction mediated through adenylate cyclase and phospholipase C pathways. 
  • Dynamic Trial-by-Trial Recoding of Task-Set Representations in the Frontoparietal Cortex Mediates Behavioral Flexibility. 
  • Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging. 
  • Electrically evoked saccades from the dorsomedial frontal cortex and frontal eye fields: a parametric evaluation reveals differences between areas. 
  • Electrophysiological activity underlying inhibitory control processes in normal adults. 
  • Electrophysiological and diffusion tensor imaging evidence of delayed corollary discharges in patients with schizophrenia. 
  • Emotion-attention network interactions during a visual oddball task. 
  • Enhanced optical imaging of rat gliomas and tumor margins. 
  • Epigenetic assimilation in the aging human brain. 
  • Event-related potentials of recognizing happy and neutral faces. 
  • Evidence of gray matter reduction and dysfunction in chromosome 22q11.2 deletion syndrome. 
  • Exogenous vs. endogenous attention: Shifting the balance of fronto-parietal activity. 
  • Eye fields in the frontal lobes of primates. 
  • Fibroblast growth factor23 is associated with axonal integrity and neural network architecture in the human frontal lobes. 
  • Focal brain dysfunction in a 41-year old man with familial alternating hemiplegia. 
  • Frontal and parietal cortical ensembles predict single-trial muscle activity during reaching movements in primates. 
  • Frontal brain electrical activity in infants of depressed and nondepressed mothers: relation to variations in infant behavior. 
  • Frontal electroencephalographic correlates of individual differences in emotion expression in infants: a brain systems perspective on emotion. 
  • Frontal eye field neurons assess visual stability across saccades. 
  • Frontal lobe activity and affective behavior of infants of mothers with depressive symptoms. 
  • Frontal lobe personality syndromes. Ominous sequelae of head trauma. 
  • Frontal lobe trauma in the elderly. Personality changes aren't always dementia. 
  • Frontal-striatum dysfunction during reward processing: Relationships to amotivation in schizophrenia. 
  • Frontoparietal activation during visual conjunction search: Effects of bottom-up guidance and adult age. 
  • Frontoparietal attentional network activation differs between smokers and nonsmokers during affective cognition. 
  • Frontostriatal white matter integrity mediates adult age differences in probabilistic reward learning. 
  • Functional connectivity predictors of acute depression treatment outcome. 
  • Functional neuroimaging studies of aging and emotion: fronto-amygdalar differences during emotional perception and episodic memory. 
  • Functional parcellation of attentional control regions of the brain. 
  • Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues. 
  • Genome-wide association study of obsessive-compulsive disorder. 
  • Hierarchical cognitive control deficits following damage to the human frontal lobe. 
  • Hierarchically Organized Medial Frontal Cortex-Basal Ganglia Loops Selectively Control Task- and Response-Selection. 
  • Hippocampal abnormalities in depression. 
  • Hypnosis decouples conflict monitoring and cognitive control functions of the frontal lobe 
  • Identification of distinct and overlapping cortical areas for bilingual naming and reading using cortical stimulation. Case report. 
  • Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. 
  • Imaging frontostriatal function in ultra-high-risk, early, and chronic schizophrenia during executive processing. 
  • In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants. 
  • Increased brain apparent diffusion coefficient in children with neurofibromatosis type 1. 
  • Individual variation in intentionality in the mind-wandering state is reflected in the integration of the default-mode, fronto-parietal, and limbic networks. 
  • Infant EEG and temperament negative affectivity: Coherence of vulnerabilities to mothers' perinatal depression. 
  • Infants of depressed and nondepressed mothers exhibit differences in frontal brain electrical activity during the expression of negative emotions. 
  • Infants of depressed mothers exhibit atypical frontal brain activity: a replication and extension of previous findings. 
  • Infants of depressed mothers exhibit atypical frontal electrical brain activity during interactions with mother and with a familiar, nondepressed adult. 
  • Influence of the thalamus on spatial visual processing in frontal cortex. 
  • Inhibition of Manual Movements at Speech Arrest Sites in the Posterior Inferior Frontal Lobe. 
  • Inhibitory control in children with attention-deficit/hyperactivity disorder: event-related potentials identify the processing component and timing of an impaired right-frontal response-inhibition mechanism. 
  • Isolated intracranial Rosai-Dorfman disease in a child. 
  • Late-life depression and microstructural abnormalities in dorsolateral prefrontal cortex white matter. 
  • Left orbital frontal cortex volume and performance on the benton visual retention test in older depressives and controls. 
  • Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype. 
  • Lobar distribution of lesion volumes in late-life depression: the Biomedical Informatics Research Network (BIRN). 
  • Measurement of spontaneous signal fluctuations in fMRI: adult age differences in intrinsic functional connectivity. 
  • Medial versus lateral frontal lobe contributions to voluntary saccade control as revealed by the study of patients with frontal lobe degeneration. 
  • Mild cognitive impairment: evaluation with 4-T functional MR imaging. 
  • Modulation of NMDA and AMPA-mediated synaptic transmission by CB1 receptors in frontal cortical pyramidal cells. 
  • Neural activity during natural viewing of Sesame Street statistically predicts test scores in early childhood. 
  • Neural correlates of genetically abnormal social cognition in Williams syndrome. 
  • Neural correlates of idiographic goal priming in depression: goal-specific dysfunctions in the orbitofrontal cortex. 
  • Neural implementation of Bayesian inference in a sensorimotor behavior. 
  • Neural mechanisms of risky decision-making and reward response in adolescent onset cannabis use disorder. 
  • Neural mechanisms of top-down control during spatial and feature attention. 
  • Neurocognitive impairments in boys on the life-course persistent antisocial path. 
  • Neuronal correlates of metacognition in primate frontal cortex. 
  • Neuronal correlates of serial decision-making in the supplementary eye field 
  • Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684. 
  • Nicotine increases anterior insula activation to expected and unexpected outcomes among nonsmokers. 
  • Nicotine withdrawal modulates frontal brain function during an affective Stroop task. 
  • Ophthalmology issues in schizophrenia. 
  • Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling. 
  • Optical imaging of epileptiform and functional activity in human cerebral cortex. 
  • Orbitofrontal and hippocampal contributions to memory for face-name associations: the rewarding power of a smile. 
  • Orbitofrontal cortex volume and intrinsic religiosity in non-clinical psychosis. 
  • Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. 
  • Orbitofrontal ensemble activity monitors licking and distinguishes among natural rewards. 
  • Organizational changes in cholinergic activity and enhanced visuospatial memory as a function of choline administered prenatally or postnatally or both. 
  • Painful generalised clonic and tonic-clonic seizures with retained consciousness. 
  • Performance feedback deficit in geriatric depression. 
  • Performance of nonpsychotic relatives of schizophrenic patients on cognitive tests. 
  • Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism network. 
  • Physical Activity Predicts Population-Level Age-Related Differences in Frontal White Matter. 
  • Postsynaptic Mechanisms Render Syn I/II/III Mice Highly Responsive to Psychostimulants. 
  • Predictive codes for forthcoming perception in the frontal cortex. 
  • Prefrontal cortex and cognitive control: motivating functional hierarchies. 
  • Prefrontal mechanisms for executive control over emotional distraction are altered in major depression. 
  • Prepartum, postpartum, and chronic depression effects on newborns. 
  • Preschool outcomes of children of depressed mothers: role of maternal behavior, contextual risk, and children's brain activity. 
  • Prominent reduction in pyramidal neurons density in the orbitofrontal cortex of elderly depressed patients. 
  • Quantitative analysis of T2 signal intensities in Alzheimer's disease. 
  • Que PASA? The posterior-anterior shift in aging. 
  • Real-time prediction of hand trajectory by ensembles of cortical neurons in primates. 
  • Recollection- and familiarity-based memory in healthy aging and amnestic mild cognitive impairment. 
  • Reduced amygdala response in youths with disruptive behavior disorders and psychopathic traits: decreased emotional response versus increased top-down attention to nonemotional features. 
  • Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims. 
  • Reduced dopamine receptors and transporters but not synthesis capacity in normal aging adults: a meta-analysis. 
  • Reflex seizures and non-ketotic hyperglycemia: an unresolved issue. 
  • Regulation of the gain of visually guided smooth-pursuit eye movements by frontal cortex. 
  • Relative right versus left frontal EEG in neonates. 
  • Repetitive transcranial magnetic stimulation of the superior frontal gyrus modulates craving for cigarettes. 
  • Response-level processing during visual feature search: Effects of frontoparietal activation and adult age. 
  • Reversible inactivation of macaque dorsomedial frontal cortex: effects on saccades and fixations. 
  • Right frontal EEG and pregnancy/neonatal outcomes. 
  • Robust Resilience of the Frontotemporal Syntax System to Aging. 
  • Role of the inferior frontal cortex in coping with distracting emotions. 
  • Selective neuronal death after transient forebrain ischemia in the Mongolian gerbil: a silver impregnation study. 
  • Sensory-motor transformations for speech occur bilaterally. 
  • Serial linkage of target selection for orienting and tracking eye movements. 
  • Signal, Noise, and Variation in Neural and Sensory-Motor Latency. 
  • Similar prevalence and magnitude of auditory-evoked and visually-evoked activity in the frontal eye fields: Implications for multisensory motor control 
  • Similarities and differences in the neural correlates of episodic memory retrieval and working memory. 
  • Skull-fixated fiducial markers improve accuracy in staged frameless stereotactic epilepsy surgery in children. 
  • Sleep deprivation elevates expectation of gains and attenuates response to losses following risky decisions. 
  • Smoking withdrawal modulates right inferior frontal cortex but not presupplementary motor area activation during inhibitory control. 
  • Smoking withdrawal shifts the spatiotemporal dynamics of neurocognition. 
  • Staged laser interstitial thermal therapy and topectomy for complete obliteration of complex focal cortical dysplasias. 
  • Structural connectivity of the frontal lobe in children with drug-resistant partial epilepsy. 
  • Subcortical lesion severity and orbitofrontal cortex volume in geriatric depression. 
  • Supratentorial tanycytic ependymoma. 
  • Synergistic effects of marijuana abuse and HIV infection on neural activation during a cognitive interference task. 
  • Task difficulty modulates brain activation in the emotional oddball task. 
  • The effect of SNCA 3' region on the levels of SNCA-112 splicing variant. 
  • The neural circuitry underlying the executive control of auditory spatial attention. 
  • The neural mechanisms of gustation: a distributed processing code. 
  • The neural underpinnings of how reward associations can both guide and misguide attention. 
  • The psychobiology of neglect. 
  • The role of frontal lobe functioning in the development of infant self-regulatory behavior. 
  • The role of the frontal pursuit area in learning in smooth pursuit eye movements. 
  • The vascular depression subtype: evidence of internal validity. 
  • The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats. 
  • Trajectories of maternal depression over 7 years: relations with child psychophysiology and behavior and role of contextual risks. 
  • Transcriptome analysis of cortical tissue reveals shared sets of downregulated genes in autism and schizophrenia. 
  • Treatment course with antidepressant therapy in late-life depression. 
  • Tryptophan hydroxylase-2 controls brain serotonin synthesis. 
  • Unaltered neuronal and glial counts in animal models of magnetic seizure therapy and electroconvulsive therapy. 
  • Uncinate fasciculus fractional anisotropy correlates with typical use of reappraisal in women but not men. 
  • Uptake and release of norepinephrine by serotonergic terminals in norepinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors. 
  • Use of subdural grids and strip electrodes to identify a seizure focus in children. 
  • Variability in frontotemporal brain structure: the importance of recruitment of African Americans in neuroscience research. 
  • Visual perception and corollary discharge. 
  • Volumetric brain imaging studies in the elderly with mood disorders. 
  • Voxel-based morphometric multisite collaborative study on schizophrenia. 
  • What the brain stem tells the frontal cortex. I. Oculomotor signals sent from superior colliculus to frontal eye field via mediodorsal thalamus. 
  • What the brain stem tells the frontal cortex. II. Role of the SC-MD-FEF pathway in corollary discharge. 
  • Where is ELSA? The early to late shift in aging. 
  • [Identification and evaluation of properties of benzodiazepine receptors of glial and neuronal fractions of human cerebral cortex]. 
  • fMRI of alterations in reward selection, anticipation, and feedback in major depressive disorder. 
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  Keywords of People

  • Cabeza, Roberto, Professor of Psychology and Neuroscience, Duke Science & Society
  • Egner, Tobias, Professor of Psychology and Neuroscience, Duke Science & Society
  • Nicolelis, Miguel Angelo L., Duke School of Medicine Professor in Neuroscience, Neurobiology