Fungal Proteins

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  Subject Areas on Research

  • 15N, 13C and 1H resonance assignments of FKBP12 proteins from the pathogenic fungi Mucor circinelloides and Aspergillus fumigatus. 
  • 5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus. 
  • A Fungal Arrestin Protein Contributes to Cell Cycle Progression and Pathogenesis. 
  • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. 
  • A Novel Mycovirus Evokes Transcriptional Rewiring in the Fungus Malassezia and Stimulates Beta Interferon Production in Macrophages. 
  • A Novel Resistance Pathway for Calcineurin Inhibitors in the Human-Pathogenic Mucorales Mucor circinelloides. 
  • A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii. 
  • A PCR-based strategy to generate integrative targeting alleles with large regions of homology. 
  • A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans. 
  • A STE12 homolog is required for mating but dispensable for filamentation in candida lusitaniae. 
  • A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. 
  • A cis-acting sequence homologous to the yeast filamentation and invasion response element regulates expression of a pectinase gene from the bean pathogen Colletotrichum lindemuthianum. 
  • A conserved G₁ regulatory circuit promotes asynchronous behavior of nuclei sharing a common cytoplasm. 
  • A conserved sorting-associated protein is mutant in chorea-acanthocytosis. 
  • A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. 
  • A family of ubiquitin-like proteins binds the ATPase domain of Hsp70-like Stch. 
  • A flucytosine-responsive Mbp1/Swi4-like protein, Mbs1, plays pleiotropic roles in antifungal drug resistance, stress response, and virulence of Cryptococcus neoformans. 
  • A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome. 
  • A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformans. 
  • A gene duplication of a septin reveals a developmentally regulated filament length control mechanism. 
  • A glucan synthase FKS1 homolog in cryptococcus neoformans is single copy and encodes an essential function. 
  • A glycosylphosphatidylinositol anchor is required for membrane localization but dispensable for cell wall association of chitin deacetylase 2 in Cryptococcus neoformans. 
  • A human protein related to yeast Cdc6p. 
  • A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis. 
  • A new face of the Rhesus antigen. 
  • A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides. 
  • A non-canonical RNAi pathway controls virulence and genome stability in Mucorales. 
  • A novel immunomodulatory protein from Poria cocos induces Toll-like receptor 4-dependent activation within mouse peritoneal macrophages. 
  • A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast. 
  • A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development, and virulence of Cryptococcus neoformans. 
  • Activation of an EDS1-mediated R-gene pathway in the snc1 mutant leads to constitutive, NPR1-independent pathogen resistance. 
  • Activation of the yeast Arp2/3 complex by Bee1p, a WASP-family protein. 
  • Adenylyl cyclase G, an osmosensor controlling germination of Dictyostelium spores. 
  • AgSwe1p regulates mitosis in response to morphogenesis and nutrients in multinucleated Ashbya gossypii cells. 
  • Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes. 
  • Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro. 
  • Amt2 permease is required to induce ammonium-responsive invasive growth and mating in Cryptococcus neoformans. 
  • An amphipathic helix enables septins to sense micrometer-scale membrane curvature. 
  • Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases. 
  • Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins. 
  • Analysis of cytoplasmic antigens of the yeast and mycelial phases of Candida albicans by two-dimensional electrophoresis. 
  • Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiae. 
  • Antifungal treatment in pediatric patients. 
  • Aquaporin expression and freeze tolerance in Candida albicans. 
  • Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. 
  • Aspergillus fumigatus calcipressin CbpA is involved in hyphal growth and calcium homeostasis. 
  • Assessing reproductive isolation in highly diverse communities of the lichen-forming fungal genus peltigera. 
  • Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics. 
  • Asynchronous nuclear division cycles in multinucleated cells. 
  • Axl2 integrates polarity establishment, maintenance, and environmental stress response in the filamentous fungus Ashbya gossypii. 
  • Binding sites on microtubules of kinesin motors of the same or opposite polarity. 
  • Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity. 
  • Breakthrough invasive candidiasis in patients on micafungin. 
  • CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90. 
  • COPII and secretory cargo capture into transport vesicles. 
  • COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. 
  • Ca(2+)/calmodulin-dependent kinase is essential for both growth and nuclear division in Aspergillus nidulans. 
  • Calcineurin Targets Involved in Stress Survival and Fungal Virulence. 
  • Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis. 
  • Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae. 
  • Calcineurin is required for virulence of Cryptococcus neoformans. 
  • Calcineurin localizes to the hyphal septum in Aspergillus fumigatus: implications for septum formation and conidiophore development. 
  • Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. 
  • Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans. 
  • Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus. 
  • Calcineurin, Mpk1 and Hog1 MAPK pathways independently control fludioxonil antifungal sensitivity in Cryptococcus neoformans. 
  • Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus. 
  • Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus. 
  • Calcium-myristoyl switches turn on new lights. 
  • Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus. 
  • Cch1 mediates calcium entry in Cryptococcus neoformans and is essential in low-calcium environments. 
  • Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha. 
  • Cell surface polarization during yeast mating. 
  • Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. 
  • Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions. 
  • Changes in the cell surface of the dimorphic forms of Candida albicans by treatment with hydrolytic enzymes. 
  • Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans. 
  • Characterization of additional components of the environmental pH-sensing complex in the pathogenic fungus Cryptococcus neoformans. 
  • Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe. 
  • Characterization of avian and viral p60src proteins expressed in yeast. 
  • Characterization of the energy-dependent, mating factor-activated Ca2+ influx in Saccharomyces cerevisiae. 
  • Characterizing the role of RNA silencing components in Cryptococcus neoformans. 
  • Chemical Denaturation and Protein Precipitation Approach for Discovery and Quantitation of Protein-Drug Interactions. 
  • Chitinases are essential for sexual development but not vegetative growth in Cryptococcus neoformans. 
  • Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii. 
  • Chlamydospore formation during hyphal growth in Cryptococcus neoformans. 
  • Chromosomal translocation and segmental duplication in Cryptococcus neoformans. 
  • Clustered nuclei maintain autonomy and nucleocytoplasmic ratio control in a syncytium. 
  • Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach. 
  • Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. 
  • Comparative genomics applied to Mucor species with different lifestyles. 
  • Comparative transcriptome analysis of the CO2 sensing pathway via differential expression of carbonic anhydrase in Cryptococcus neoformans. 
  • Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans. 
  • Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. 
  • Complexities associated with the molecular and proteomic identification of Paecilomyces species in the clinical mycology laboratory. 
  • Components of a new gene family of ferroxidases involved in virulence are functionally specialized in fungal dimorphism. 
  • Condensin and cohesin display different arm conformations with characteristic hinge angles. 
  • Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom. 
  • Conserved elements of the RAM signaling pathway establish cell polarity in the basidiomycete Cryptococcus neoformans in a divergent fashion from other fungi. 
  • Construction of a Recyclable Genetic Marker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides. 
  • Contribution of RPB2 to multilocus phylogenetic studies of the euascomycetes (Pezizomycotina, Fungi) with special emphasis on the lichen-forming Acarosporaceae and evolution of polyspory. 
  • Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. 
  • Control of filamentous fungal cell shape by septins and formins. 
  • Control of meiotic recombination and gene expression in yeast by a simple repetitive DNA sequence that excludes nucleosomes. 
  • Convergent evolution of linked mating-type loci in basidiomycete fungi. 
  • Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae. 
  • Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex. 
  • Cryo-EM structure of a mitochondrial calcium uniporter. 
  • Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli. 
  • Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis. 
  • Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. 
  • Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses. 
  • Cryptococcus neoformans copper detoxification machinery is critical for fungal virulence. 
  • Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host. 
  • Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype. 
  • Cryptococcus neoformans, a fungus under stress. 
  • Cryptococcus neoformans: a sugar-coated killer with designer genes. 
  • Cryptococcus neoformans: the yeast that likes it hot. 
  • Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design. 
  • Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate. 
  • Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin. 
  • DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair. 
  • DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae. 
  • DNA replication and progression through the cell cycle. 
  • Decoupling of nucleotide- and microtubule-binding sites in a kinesin mutant. 
  • Decreased meiotic intergenic recombination and increased meiosis I nondisjunction in exo1 mutants of Saccharomyces cerevisiae. 
  • Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition. 
  • Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. 
  • Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae. 
  • Development and evaluation of a real-time polymerase chain reaction assay for the rapid detection of Talaromyces marneffei MP1 gene in human plasma. 
  • Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment. 
  • Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus. 
  • Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. 
  • Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization. 
  • Discovery of a modified tetrapolar sexual cycle in Cryptococcus amylolentus and the evolution of MAT in the Cryptococcus species complex. 
  • Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. 
  • Distinct and redundant roles of exonucleases in Cryptococcus neoformans: implications for virulence and mating. 
  • Echinocandins: role in antifungal therapy, 2005. 
  • Effect of alpha-isopropylmalate on the synthesis of RNA and protein in Neurospora. 
  • Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae. 
  • Efficient sporulation of yeast in media buffered near pH6. 
  • Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence. 
  • Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans. 
  • Emerging Issues in Antifungal Resistance. 
  • Enfumafungin synthase represents a novel lineage of fungal triterpene cyclases. 
  • Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen. 
  • Erbin is a protein concentrated at postsynaptic membranes that interacts with PSD-95. 
  • Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo. 
  • Evidence for a disease-resistance pathway in rice similar to the NPR1-mediated signaling pathway in Arabidopsis. 
  • Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle. 
  • Evolution of the sex-related locus and genomic features shared in microsporidia and fungi. 
  • Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex. 
  • Extension of O-Linked Mannosylation in the Golgi Apparatus Is Critical for Cell Wall Integrity Signaling and Interaction with Host Cells in Cryptococcus neoformans Pathogenesis. 
  • FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus. 
  • FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia. 
  • Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae. 
  • Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi. 
  • Fine-structure mapping of meiosis-specific double-strand DNA breaks at a recombination hotspot associated with an insertion of telomeric sequences upstream of the HIS4 locus in yeast. 
  • Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. 
  • Function of Cryptococcus neoformans KAR7 (SEC66) in karyogamy during unisexual and opposite-sex mating. 
  • Function of the thioredoxin proteins in Cryptococcus neoformans during stress or virulence and regulation by putative transcriptional modulators. 
  • Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds. 
  • Fungal and algal gene expression in early developmental stages of lichen-symbiosis. 
  • G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans. 
  • G protein-coupled receptor Gpr4 senses amino acids and activates the cAMP-PKA pathway in Cryptococcus neoformans. 
  • Gene Expression of Diverse Cryptococcus Isolates during Infection of the Human Central Nervous System. 
  • Gene Network Polymorphism Illuminates Loss and Retention of Novel RNAi Silencing Components in the Cryptococcus Pathogenic Species Complex. 
  • Genetic Dissection of Sexual Reproduction in a Primary Homothallic Basidiomycete. 
  • Genetic circuits that govern bisexual and unisexual reproduction in Cryptococcus neoformans. 
  • Genetic dissection of systemic acquired resistance. 
  • Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break. 
  • Genome-wide analysis of the regulation of Cu metabolism in Cryptococcus neoformans. 
  • Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans. 
  • Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase. 
  • Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis. 
  • Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. 
  • Glutamine metabolism during aerial mycelium growth of Neurospora crassa. 
  • Glutamine requirement for aerial mycelium growth in Neurospora crassa. 
  • Going green in Cryptococcus neoformans: the recycling of a selectable drug marker. 
  • Good fungi gone bad: the corruption of calcineurin. 
  • Gpr1, a putative G-protein-coupled receptor, regulates morphogenesis and hypha formation in the pathogenic fungus Candida albicans. 
  • Gradated assembly of multiple proteins into supramolecular nanomaterials. 
  • Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis. 
  • Guides to the final frontier of the cytoskeleton: septins in filamentous fungi. 
  • HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction. 
  • Had1 Is Required for Cell Wall Integrity and Fungal Virulence in Cryptococcus neoformans. 
  • Heterogeneity in mitochondrial morphology and membrane potential is independent of the nuclear division cycle in multinucleate fungal cells. 
  • Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae. 
  • Heterotrimeric G-alpha subunits Gpa11 and Gpa12 define a transduction pathway that control spore size and virulence in Mucor circinelloides. 
  • Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomerase. 
  • Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants. 
  • Hostile takeover: fungal protein promotes host cell invasion. 
  • Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus. 
  • Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. 
  • Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. 
  • Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity. 
  • Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans. 
  • Identification and characterization of an SKN7 homologue in Cryptococcus neoformans. 
  • Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans. 
  • Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarray. 
  • Identification of a Cryptococcus neoformans gene that directs expression of the cryptic Saccharomyces cerevisiae mannitol dehydrogenase gene. 
  • Identification of cell cycle-regulated, putative hyphal genes in Candida albicans. 
  • Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts. 
  • Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate. 
  • Identification of the sex genes in an early diverged fungus. 
  • Identification of yeast mutants with altered telomere structure. 
  • Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta. 
  • Identifying a novel connection between the fungal plasma membrane and pH-sensing. 
  • Impact of Protein Palmitoylation on the Virulence Potential of Cryptococcus neoformans. 
  • Impact of ammonium permeases mepA, mepB, and mepC on nitrogen-regulated secondary metabolism in Fusarium fujikuroi. 
  • Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes. 
  • In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus. 
  • In vitro reconstitution of cortical actin assembly sites in budding yeast. 
  • Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta. 
  • Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations. 
  • Inhibitor-1 interaction domain that mediates the inhibition of protein phosphatase-1. 
  • Inositol Metabolism Regulates Capsule Structure and Virulence in the Human Pathogen Cryptococcus neoformans. 
  • Insights from the first putative biosynthetic gene cluster for a lichen depside and depsidone. 
  • Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). 
  • Instability of simple sequence DNA in Saccharomyces cerevisiae. 
  • Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. 
  • Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule. 
  • Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene. 
  • Interactions between copper homeostasis and the fungal cell wall affect copper stress resistance. 
  • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. 
  • Intracellular Action of a Secreted Peptide Required for Fungal Virulence. 
  • Investigating Conservation of the Cell-Cycle-Regulated Transcriptional Program in the Fungal Pathogen, Cryptococcus neoformans. 
  • Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. 
  • Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. 
  • Isolation and characterization of effector-loop mutants of CDC42 in yeast. 
  • Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast. 
  • Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha. 
  • Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe. 
  • Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites. 
  • KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans. 
  • Keeping the beat in the rising heat. 
  • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. 
  • Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus. 
  • Large-scale genome sequencing of mycorrhizal fungi provides insights into the early evolution of symbiotic traits. 
  • Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs. 
  • Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae. 
  • Limited functional redundancy and oscillation of cyclins in multinucleated Ashbya gossypii fungal cells. 
  • Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. 
  • Loss of allergen 1 confers a hypervirulent phenotype that resembles mucoid switch variants of Cryptococcus neoformans. 
  • MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae. 
  • MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2. 
  • Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi. 
  • Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. 
  • Management of invasive mycoses in hematology patients: current approaches. 
  • Mating-Type-Specific Ribosomal Proteins Control Aspects of Sexual Reproduction in Cryptococcus neoformans. 
  • Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans. 
  • Maximal polar growth potential depends on the polarisome component AgSpa2 in the filamentous fungus Ashbya gossypii. 
  • Maximal stimulation of meiotic recombination by a yeast transcription factor requires the transcription activation domain and a DNA-binding domain. 
  • Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts. 
  • Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops. 
  • Metatranscriptomic Study of Common and Host-Specific Patterns of Gene Expression between Pines and Their Symbiotic Ectomycorrhizal Fungi in the Genus Suillus. 
  • Metatranscriptomic analysis of ectomycorrhizal roots reveals genes associated with Piloderma-Pinus symbiosis: improved methodologies for assessing gene expression in situ. 
  • Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I). 
  • Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast. 
  • Mitochondrial FtsZ in a chromophyte alga 
  • Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae. 
  • Molecular Tools for the Yeast Papiliotrema terrestris LS28 and Identification of Yap1 as a Transcription Factor Involved in Biocontrol Activity. 
  • Molecular characterization of CLPT1, a SEC4-like Rab/GTPase of the phytopathogenic fungus Colletotrichum lindemuthianum which is regulated by the carbon source. 
  • Morphogenesis of Candida albicans and cytoplasmic proteins associated with differences in morphology, strain, or temperature. 
  • Multiple Pathways to Homothallism in Closely Related Yeast Lineages in the Basidiomycota. 
  • Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. 
  • Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii. 
  • Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development. 
  • Neurospora crassa female development requires the PACC and other signal transduction pathways, transcription factors, chromatin remodeling, cell-to-cell fusion, and autophagy. 
  • New species of Clavulina (Cantharellales, Basidiomycota) with resupinate and effused basidiomata from the Guiana Shield. 
  • Ninety-six haploid yeast strains with individual disruptions of open reading frames between YOR097C and YOR192C, constructed for the Saccharomyces genome deletion project, have an additional mutation in the mismatch repair gene MSH3. 
  • Nomenclature: vertebrate mediators of TGFbeta family signals. 
  • Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication. 
  • Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans. 
  • Nuclear anarchy: asynchronous mitosis in multinucleated fungal hyphae. 
  • Nuclear localization of NPR1 is required for activation of PR gene expression. 
  • O-glycosylation as a sorting determinant for cell surface delivery in yeast. 
  • Oral administration of an Enoki mushroom protein FVE activates innate and adaptive immunity and induces anti-tumor activity against murine hepatocellular carcinoma. 
  • Ordered kinetochore assembly in the human-pathogenic basidiomycetous yeast Cryptococcus neoformans. 
  • Organizing mRNA export. 
  • Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. 
  • PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans. 
  • PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans. 
  • PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. 
  • PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans. 
  • PRD-2 mediates clock-regulated perinuclear localization of clock gene RNAs within the circadian cycle of Neurospora. 
  • PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex. 
  • Pathogen virulence factors as molecular probes of basic plant cellular functions. 
  • Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans. 
  • Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe. 
  • Phenotypic and genotypic evaluation of fluconazole resistance in vaginal Candida strains isolated from HIV-infected women from Brazil. 
  • Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition. 
  • Phosphoproteome analysis in yeast. 
  • Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity. 
  • Phosphorylation of Aspergillus fumigatus PkaR impacts growth and cell wall integrity through novel mechanisms. 
  • Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus. 
  • Phycomyces MADB interacts with MADA to form the primary photoreceptor complex for fungal phototropism. 
  • Phylogeny and evolution of medical species of Candida and related taxa: a multigenic analysis. 
  • Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora. 
  • Pim1 Kinase Overexpression Enhances ckit+ Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine. 
  • Pleiotropic roles of the Msi1-like protein Msl1 in Cryptococcus neoformans. 
  • Ploidy variation in multinucleate cells changes under stress. 
  • PolyQ-dependent RNA-protein assemblies control symmetry breaking. 
  • Polyporales genomes reveal the genetic architecture underlying tetrapolar and bipolar mating systems. 
  • Polysaccharides PS-G and protein LZ-8 from Reishi (Ganoderma lucidum) exhibit diverse functions in regulating murine macrophages and T lymphocytes. 
  • Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans. 
  • Population perspectives on functional genomic variation in yeast. 
  • Positive and negative selection LYS5MX gene replacement cassettes for use in Saccharomyces cerevisiae. 
  • Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans. 
  • Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts. 
  • Protection from nitrosative stress by yeast flavohemoglobin. 
  • Protein aggregation behavior regulates cyclin transcript localization and cell-cycle control. 
  • Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. 
  • Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast. 
  • Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. 
  • Protein serine/threonine phosphatases--new avenues for cell regulation. 
  • Proteogenomics produces comprehensive and highly accurate protein-coding gene annotation in a complete genome assembly of Malassezia sympodialis. 
  • Pseudohyphal growth of Cryptococcus neoformans is a reversible dimorphic transition in response to ammonium that requires Amt1 and Amt2 ammonium permeases. 
  • Purification of alpha-sarcin and an antifungal protein from Aspergillus giganteus by blue sepharose CL-6B affinity chromatography. 
  • RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans. 
  • RNA Controls PolyQ Protein Phase Transitions. 
  • RNAi-Based Functional Genomics Identifies New Virulence Determinants in Mucormycosis. 
  • Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR. 
  • Rapamycin exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependent inhibition of Tor. 
  • Rapid purification of microtubule motor domain proteins expressed in bacteria. 
  • Ras1 acts through duplicated Cdc42 and Rac proteins to regulate morphogenesis and pathogenesis in the human fungal pathogen Cryptococcus neoformans. 
  • Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans. 
  • Ras1 controls pheromone expression and response during mating in Cryptococcus neoformans. 
  • Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. 
  • Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. 
  • Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas. 
  • Reg1p targets protein phosphatase 1 to dephosphorylate hexokinase II in Saccharomyces cerevisiae: characterizing the effects of a phosphatase subunit on the yeast proteome. 
  • Regulation of distinct septin rings in a single cell by Elm1p and Gin4p kinases. 
  • Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. 
  • Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. 
  • Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans. 
  • Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase. 
  • Reinterpretation of GCN4-p1 folding kinetics: partial helix formation precedes dimerization in coiled coil folding. 
  • Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae. 
  • Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans. 
  • Remodeling of global transcription patterns of Cryptococcus neoformans genes mediated by the stress-activated HOG signaling pathways. 
  • Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae. 
  • Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins. 
  • Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. 
  • Restricted substrate specificity for the geranylgeranyltransferase-I enzyme in Cryptococcus neoformans: implications for virulence. 
  • Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans. 
  • Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation. 
  • Role for topoisomerase 1 in transcription-associated mutagenesis in yeast. 
  • Role of Arf-like proteins (Arl1 and Arl2) of Mucor circinelloides in virulence and antifungal susceptibility. 
  • Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. 
  • Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 signaling pathway in response to thermal stress. 
  • Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production. 
  • Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium. 
  • Role of mismatch repair in the fidelity of RAD51- and RAD59-dependent recombination in Saccharomyces cerevisiae. 
  • Role of protein O-mannosyltransferase Pmt4 in the morphogenesis and virulence of Cryptococcus neoformans. 
  • Roles for Stress Response and Cell Wall Biosynthesis Pathways in Caspofungin Tolerance in Cryptococcus neoformans. 
  • SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. 
  • SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. 
  • SILAC-pulse proteolysis: A mass spectrometry-based method for discovery and cross-validation in proteome-wide studies of ligand binding. 
  • SP75 is encoded by the DP87 gene and belongs to a family of modular Dictyostelium discoideum outer layer spore coat proteins. 
  • SXI1alpha controls uniparental mitochondrial inheritance in Cryptococcus neoformans. 
  • Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome. 
  • Sad1 Spatiotemporally Regulates Kinetochore Clustering To Ensure High-Fidelity Chromosome Segregation in the Human Fungal Pathogen Cryptococcus neoformans. 
  • Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs. 
  • Secondary structure of a leucine zipper determined by nuclear magnetic resonance spectroscopy. 
  • Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing. 
  • Septin phosphorylation and coiled-coil domains function in cell and septin ring morphology in the filamentous fungus Ashbya gossypii. 
  • Septin ring size scaling and dynamics require the coiled-coil region of Shs1p. 
  • Septins and Generation of Asymmetries in Fungal Cells. 
  • Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans. 
  • Septins may form a ubiquitous family of cytoskeletal filaments. 
  • Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae. 
  • Sex-specific homeodomain proteins Sxi1alpha and Sxi2a coordinately regulate sexual development in Cryptococcus neoformans. 
  • Signal transduction cascades regulating pseudohyphal differentiation of Saccharomyces cerevisiae. 
  • Site-Specific K63 Ubiquitinomics Provides Insights into Translation Regulation under Stress. 
  • Sok2 regulates yeast pseudohyphal differentiation via a transcription factor cascade that regulates cell-cell adhesion. 
  • Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformans. 
  • Specificity and regulation of a synaptic vesicle docking complex. 
  • Spliceosomal immunophilins. 
  • Sterol-Response Pathways Mediate Alkaline Survival in Diverse Fungi. 
  • Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis. 
  • Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy. 
  • Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. 
  • Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. 
  • Structures of yeast vesicle trafficking proteins. 
  • Subcellular localization directs signaling specificity of the Cryptococcus neoformans Ras1 protein. 
  • Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway in Cryptococcus neoformans and contributes to fungal virulence. 
  • Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis. 
  • Systematic functional profiling of transcription factor networks in Cryptococcus neoformans. 
  • TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. 
  • The 40-kilodalton allergen of Candida albicans is an alcohol dehydrogenase: molecular cloning and immunological analysis using monoclonal antibodies. 
  • The ATP binding site of the yeast plasma membrane proton-translocating ATPase. 
  • The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome. 
  • The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans. 
  • The Cryptococcus neoformans Flc1 Homologue Controls Calcium Homeostasis and Confers Fungal Pathogenicity in the Infected Hosts. 
  • The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function. 
  • The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host. 
  • The Cryptococcus neoformans alkaline response pathway: identification of a novel rim pathway activator. 
  • The Cryptococcus neoformans capsule: a sword and a shield. 
  • The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. 
  • The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery. 
  • The Evolution of Sexual Reproduction and the Mating-Type Locus: Links to Pathogenesis of Cryptococcus Human Pathogenic Fungi. 
  • The G protein-coupled receptor gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • The G-protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans. 
  • The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. 
  • The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans. 
  • The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. 
  • The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. 
  • The Pheromone and Pheromone Receptor Mating-Type Locus Is Involved in Controlling Uniparental Mitochondrial Inheritance in Cryptococcus. 
  • The Phycomyces madA gene encodes a blue-light photoreceptor for phototropism and other light responses. 
  • The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets. 
  • The RGS protein Crg2 regulates both pheromone and cAMP signalling in Cryptococcus neoformans. 
  • The STE12alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans. 
  • The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects. 
  • The TOR signal transduction cascade controls cellular differentiation in response to nutrients. 
  • The TOR signaling cascade regulates gene expression in response to nutrients. 
  • The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells. 
  • The anaphase-promoting complex/cyclosome is required for anaphase progression in multinucleated Ashbya gossypii cells. 
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. 
  • The heterotrimeric G-protein beta subunit Gpb1 controls hyphal growth under low oxygen conditions through the protein kinase A pathway and is essential for virulence in the fungus Mucor circinelloides. 
  • The high mobility group protein Abf2p influences the level of yeast mitochondrial DNA recombination intermediates in vivo. 
  • The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. 
  • The mating type locus (MAT) and sexual reproduction of Cryptococcus heveanensis: insights into the evolution of sex and sex-determining chromosomal regions in fungi. 
  • The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. 
  • The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. 
  • The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. 
  • The regulation of DNA topoisomerase II by casein kinase II. 
  • The release of acid phosphatase and polysaccharide- and protein-containing components from the surface of the dimorphic forms of Candida albicans by treatment with dithiothreitol. 
  • The role of Aspartyl aminopeptidase (Ape4) in Cryptococcus neoformans virulence and authophagy. 
  • The role of the de novo pyrimidine biosynthetic pathway in Cryptococcus neoformans high temperature growth and virulence. 
  • The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II. 
  • The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth. 
  • The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii. 
  • The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. 
  • Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans. 
  • Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans. 
  • Threonine biosynthetic genes are essential in Cryptococcus neoformans. 
  • Towards a new classification of the Arthoniales (Ascomycota) based on a three-gene phylogeny focussing on the genus Opegrapha. 
  • Transcription factor-driven alternative localization of Cryptococcus neoformans superoxide dismutase. 
  • Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans. 
  • Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae. 
  • Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin. 
  • Transitions in sexuality: recapitulation of an ancestral tri- and tetrapolar mating system in Cryptococcus neoformans. 
  • Treatment options for invasive fungal infections. 
  • Two distinct genes encode small isoproteolipids affecting plasma membrane H(+)-ATPase activity of Saccharomyces cerevisiae. 
  • Two proteins of the Dictyostelium spore coat bind to cellulose in vitro. 
  • Uniparental nuclear inheritance following bisexual mating in fungi. 
  • Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans. 
  • Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans. 
  • Unraveling the Pathobiological Role of the Fungal KEOPS Complex in Cryptococcus neoformans. 
  • Unseen sex in ancient virgin fungi. 
  • Unveiling Protein Kinase A Targets in Cryptococcus neoformans Capsule Formation. 
  • Using a multigene phylogenetic analysis to assess generic delineation and character evolution in Verrucariaceae (Verrucariales, Ascomycota). 
  • Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. 
  • Variation in efficiency of DNA mismatch repair at different sites in the yeast genome. 
  • Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. 
  • Virulence factors identified by Cryptococcus neoformans mutant screen differentially modulate lung immune responses and brain dissemination. 
  • Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity. 
  • Wsp1 is downstream of Cin1 and regulates vesicle transport and actin cytoskeleton as an effector of Cdc42 and Rac1 in Cryptococcus neoformans. 
  • X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution. 
  • Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. 
  • Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends. 
  • Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors. 
  • Yeast base excision repair: interconnections and networks. 
  • Yeast pseudohyphal growth is regulated by GPA2, a G protein alpha homolog. 
  • cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I. 
  • hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage. 
  • vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly. 
• 

  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Shinohara, Mari L., Professor of Integrative Immunobiology, Cell Biology