Galactosyltransferases
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Subject Areas on Research
- A whole genome approach for discovering the genetic basis of blood group antigens: independent confirmation for P1 and Xga .
- Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.
- Coagulopathy in α-galactosyl transferase knockout pulmonary xenotransplants.
- Dual islet transplantation modeling of the instant blood-mediated inflammatory reaction.
- Efficient generation of targeted and controlled mutational events in porcine cells using nuclease-directed homologous recombination.
- Exposure of mice to topical bovine thrombin induces systemic autoimmunity.
- Glycolipids and glycosyltransferases in permanent cell lines established from human medulloblastomas.
- HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells.
- Humoral Reactivity of Renal Transplant-Waitlisted Patients to Cells From GGTA1/CMAH/B4GalNT2, and SLA Class I Knockout Pigs.
- Identification of O-linked N-acetylglucosamine modification of ankyrinG isoforms targeted to nodes of Ranvier.
- Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function.
- Modified glycan models of pig-to-human xenotransplantation do not enhance the human-anti-pig T cell response.
- Oral feeding with pig peripheral lymphocytes decreases the xenogeneic delayed type hypersensitivity reaction in galactosyltransferase knockout mice.
- Silencing Porcine CMAH and GGTA1 Genes Significantly Reduces Xenogeneic Consumption of Human Platelets by Porcine Livers.
- Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation.
- Silencing the porcine iGb3s gene does not affect Galα3Gal levels or measures of anticipated pig-to-human and pig-to-primate acute rejection.
- The desirable donor pig to eliminate all xenoreactive antigens.
- The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs.
- Unexpected anti-alpha GalNAc antibodies in alpha-galactosyl transferase-deficient mice: complex relationship between genotype and the natural antibody repertoire.