Glutamate-Cysteine Ligase
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Subject Areas on Research
- A comparison of glutathione-dependent enzymes in liver, gills and posterior kidney of channel catfish (Ictalurus punctatus).
- Antioxidant Rescue of Selenomethionine-Induced Teratogenesis in Zebrafish Embryos.
- Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
- Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft.
- Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.
- Effects of buthionine sulfoximine and diethyl maleate on glutathione turnover in the channel catfish.
- Nitric oxide-associated regulation of hepatocyte glutathione synthesis is a guanylyl cyclase-independent event.
- Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia.
- Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events.
- Purification and biochemical characterization of gamma-glutamylcysteine synthetase from a human malignant astrocytoma cell line.
- Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis.