Gastrula

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  Subject Areas on Research

  • A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein. 
  • A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis. 
  • Allocation of epiblast cells to germ layer derivatives during mouse gastrulation as studied with a retroviral vector. 
  • Archenteron precursor cells can organize secondary axial structures in the sea urchin embryo. 
  • BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning. 
  • Beta heavy-spectrin has a restricted tissue and subcellular distribution during Drosophila embryogenesis. 
  • Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos. 
  • Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. 
  • Cell recognition processes in the differentiation of embryonic sea urchins. 
  • Changes in the pattern of adherens junction-associated beta-catenin accompany morphogenesis in the sea urchin embryo. 
  • Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo. 
  • Characterization of moesin in the sea urchin Lytechinus variegatus: redistribution to the plasma membrane following fertilization is inhibited by cytochalasin B. 
  • Characterization of the role of cadherin in regulating cell adhesion during sea urchin development. 
  • Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. 
  • Commitment along the dorsoventral axis of the sea urchin embryo is altered in response to NiCl2. 
  • Delayed transition to new cell fates during cellular reprogramming. 
  • Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. 
  • Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis. 
  • Dynamics of thin filopodia during sea urchin gastrulation. 
  • Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus. 
  • Evolutionary modification of cell lineage in the direct-developing sea urchin Heliocidaris erythrogramma. 
  • Frizzled5/8 is required in secondary mesenchyme cells to initiate archenteron invagination during sea urchin development. 
  • Gastrulation in the sea urchin embryo requires the deposition of crosslinked collagen within the extracellular matrix. 
  • Gastrulation in the sea urchin. 
  • Gastrulation. 
  • Growth factors in development: the role of TGF-beta related polypeptide signalling molecules in embryogenesis. 
  • Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4. 
  • Inhibitors of metalloendoproteases block spiculogenesis in sea urchin primary mesenchyme cells. 
  • LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo. 
  • LvNumb works synergistically with Notch signaling to specify non-skeletal mesoderm cells in the sea urchin embryo. 
  • Micromere descendants at the blastula stage are involved in normal archenteron formation in sea urchin embryos. 
  • New insights from a high-resolution look at gastrulation in the sea urchin, Lytechinus variegatus. 
  • Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. 
  • Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. 
  • Nuclear beta-catenin-dependent Wnt8 signaling in vegetal cells of the early sea urchin embryo regulates gastrulation and differentiation of endoderm and mesodermal cell lineages. 
  • Pattern formation during gastrulation in the sea urchin embryo. 
  • Promoter logic. 
  • Regulative capacity of the archenteron during gastrulation in the sea urchin. 
  • Retinoic acid-mediated gene expression in transgenic reporter zebrafish. 
  • RhoA regulates initiation of invagination, but not convergent extension, during sea urchin gastrulation. 
  • Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions. 
  • Spdeadringer, a sea urchin embryo gene required separately in skeletogenic and oral ectoderm gene regulatory networks. 
  • Surface antigens involved in interactions of embryonic sea urchin cells. 
  • Target recognition by the archenteron during sea urchin gastrulation. 
  • The DVR gene family in embryonic development. 
  • The Role of Brachyruy (T) During Gastrulations Movement in the Sea Urchin, Lytechinus variegatus 
  • The Snail repressor is required for PMC ingression in the sea urchin embryo. 
  • The allocation of early blastomeres to the ectoderm and endoderm is variable in the sea urchin embryo. 
  • The evolution of echinoderm development is driven by several distinct factors. 
  • The origin of spicule-forming cells in a 'primitive' sea urchin (Eucidaris tribuloides) which appears to lack primary mesenchyme cells. 
  • The regulation of primary mesenchyme cell migration in the sea urchin embryo: transplantations of cells and latex beads. 
  • The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. 
  • Three cell recognition changes accompany the ingression of sea urchin primary mesenchyme cells. 
  • alphaSU2, an epithelial integrin that binds laminin in the sea urchin embryo. 
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  Keywords of People

  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology