Gels

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  Subject Areas on Research

  • 5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors. 
  • A double-masked randomized trial of postoperative local anesthetic for pain control in pediatric strabismus surgery. 
  • A hybrid polymer gel with controlled rates of cross-link rupture and self-repair. 
  • A method for in-gel fluorescent visualization of proteins after native and sodium dodecyl sulfate polyacrylamide gel electrophoresis. 
  • A one-year multicenter clinical trial of pilocarpine gel. 
  • A phase III, multicenter, randomized, placebo-controlled clinical trial of topical aminocaproic acid (Caprogel) in the management of traumatic hyphema. 
  • A prospective randomized, placebo-controlled skin care study in women diagnosed with breast cancer undergoing radiation therapy. 
  • A standardized approach to PCR-based semiquantitation of multiple cytokine gene transcripts from small cell samples. 
  • A synthetic mimic of the secretory granule for drug delivery. 
  • ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations. 
  • Active scaffolds for on-demand drug and cell delivery. 
  • Adhesion contact dynamics of HepG2 cells on galactose-immobilized substrates. 
  • Affinity chromatographic purification of immunoglobulin M antibodies utilizing immobilized mannan binding protein. 
  • Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. 
  • An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration. 
  • An investigation into the dosimetry of a nine-field tomotherapy irradiation using BANG-gel dosimetry. 
  • An investigation of the accuracy of an IMRT dose distribution using two- and three-dimensional dosimetry techniques. 
  • Area per molecule and distribution of water in fully hydrated dilauroylphosphatidylethanolamine bilayers. 
  • Biophysical analysis of prototype microbicidal gels. 
  • Bone sialoprotein-collagen interaction promotes hydroxyapatite nucleation. 
  • Bone-anchored hearing aid abutment skin overgrowth reduction with clobetasol. 
  • Bulk laxative causing esophageal obstruction. 
  • CVD for the facile synthesis of hybrid nanobiomaterials integrating functional supramolecular assemblies. 
  • Cell-laden microfluidic microgels for tissue regeneration. 
  • Cervical ripening: randomized comparison of intravaginal prostaglandin E2 gel with prostaglandin E2 gel plus laminaria tents. 
  • Characterizing differences between MSCs and TM cells: Toward autologous stem cell therapies for the glaucomatous trabecular meshwork. 
  • Collagenase in bone of man. 
  • Comparison of Lidocaine Gel-Assisted Transconjunctival and Transcutaneous Local Anesthesia for Outpatient Eyelid Surgery. 
  • Comparison of covalently and physically cross-linked polyethylene glycol-based hydrogels for the prevention of postoperative adhesions in a rat model. 
  • Comparison of the rheological properties of Advantage-S and Replens. 
  • Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration. 
  • Contributions of hydration and steric (entropic) pressures to the interactions between phosphatidylcholine bilayers: experiments with the subgel phase. 
  • Corneal changes during pilocarpine gel therapy. 
  • Design of a semisolid vaginal microbicide gel by relating composition to properties and performance. 
  • Design of tenofovir-UC781 combination microbicide vaginal gels. 
  • Dietary glycine inhibits angiogenesis during wound healing and tumor growth. 
  • Dilution of microbicide gels with vaginal fluid and semen simulants: effect on rheological properties and coating flow. 
  • Discovery of protein- and DNA-imperceptible nanoparticle hard coating using gel-based reaction tuning. 
  • Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways. 
  • Dynamics of polymerization in polyacrylamide gel (PAG) dosimeters: (I) ageing and long-term stability. 
  • Early intracellular events in the replication of bacteriophage T4 deoxyribonucleic acid. VI. Newly synthesized proteins in the T4 protein-deoxyribonucleic acid complex. 
  • Effect of lidocaine gel anesthesia on endophthalmitis rates following intravitreal injection. 
  • Effect of temperature and pH on contraceptive gel viscosity. 
  • Effects of pulse strength and pulse duration on in vitro DNA electromobility. 
  • Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men. 
  • Electrochemical detector based on sol-gel-derived carbon composite material for capillary electrophoresis microchips. 
  • Erosion of microbicide formulation coating layers: effects of contact and shearing with vaginal fluid or semen. 
  • Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. 
  • Experimental characterization of intermolecular multiple-quantum coherence pumping efficiency in solution NMR. 
  • Fabrication of poly(phosphoester) nerve guides by immersion precipitation and the control of porosity. 
  • Factors affecting pain scores during female urethral catheterization. 
  • Fibrillar peptide gels in biotechnology and biomedicine. 
  • Full depth measurement of tenofovir transport in rectal mucosa using confocal Raman spectroscopy and optical coherence tomography. 
  • Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc. 
  • Gelation of liposome interior. A novel method for drug encapsulation. 
  • Gravity-induced coating flows of vaginal gel formulations: in vitro experimental analysis. 
  • Hand Sanitizer as an Alternative to Ultrasound Transmission Gel. 
  • High resolution gel-dosimetry by optical-CT and MR scanning. 
  • High-frequency stress relaxation in semiflexible polymer solutions and networks. 
  • Host response to microgel coatings on neural electrodes implanted in the brain. 
  • Human granulocyte collagenase. 
  • Hydration force and bilayer deformation: a reevaluation. 
  • Imaging appearance of surgical sponges at 1.5 T MRI: an in vitro study. 
  • Improving calibration accuracy in gel dosimetry. 
  • In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model. 
  • In vitro assessment of EmboGel and UltraGel radiopaque hydrogels for the endovascular treatment of aneurysms. 
  • In vivo optical imaging of human vaginal gel thickness distributions with a probe-based, dual-modality instrument. 
  • Incidence of autoimmune disease in patients after breast reconstruction with silicone gel implants versus autogenous tissue: a preliminary report. 
  • Increased rate of peripheral nerve regeneration using bioresorbable nerve guides and a laminin-containing gel. 
  • Interpreting properties of microbicide drug delivery gels: analyzing deployment kinetics due to squeezing. 
  • Ion therapy of prostate cancer: daily rectal dose reduction by application of spacer gel. 
  • Label-Free Measurements of Tenofovir Diffusion Coefficients in a Microbicide Gel Using Raman Spectroscopy. 
  • Label-free measurement of microbicidal gel thickness using low-coherence interferometry. 
  • Lanthanide-binding tags as versatile protein coexpression probes. 
  • Light and electron microscopy characterization of a collagen-liposome-entrapped chondroitin sulfate composite as intra-articular drug delivery system. 
  • Lipid specificity of beta-hydroxybutyrate dehydrogenase activation. 
  • Long-term pharmacokinetics of transdermal testosterone gel in hypogonadal men. 
  • Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. 
  • Macrophage embedded fibrin gels: an in vitro platform for assessing inflammation effects on implantable glucose sensors. 
  • Mammary implants, diving, and altitude exposure. 
  • Measuring dilution of microbicide gels with optical imaging. 
  • Multiplexed low coherence interferometry instrument for measuring microbicide gel thickness distribution. 
  • Multivariate analysis of attachment of biofouling organisms in response to material surface characteristics. 
  • New structural model for mixed-chain phosphatidylcholine bilayers. 
  • Noise in polymer gel measurements using MRI. 
  • Nucleation and growth synthesis of siloxane gels to form functional, monodisperse, and acoustically programmable particles. 
  • Optical-CT gel-dosimetry I: basic investigations. 
  • Optical-CT gel-dosimetry. II: Optical artifacts and geometrical distortion. 
  • PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial. 
  • Peptide-functionalized oxime hydrogels with tunable mechanical properties and gelation behavior. 
  • Polymer gel dosimetry. 
  • Polypeptides of avian RNA tumor viruses. 1. Isolation and physical and chemical analysis. 
  • Polypeptides of avian RNA tumor viruses. II. Serological characterization. 
  • Postmortem validation of the automated coronary analysis (ACA) software package. 
  • Probing the ethanol-induced chain interdigitations in gel-state bilayers of mixed-chain phosphatidylcholines. 
  • Profound increase in viscosity and aggregation of pig gastric mucin at low pH. 
  • Pulsed-field gel electrophoresis. 
  • Radiation dosimetry using polymer gels: methods and applications. 
  • Randomized Controlled Trial to Assess the Impact of Intraurethral Lidocaine on Urodynamic Voiding Parameters. 
  • Release and activity of anti-TNFalpha therapeutics from injectable chitosan preparations for local drug delivery. 
  • Rheological properties of contraceptive gels. 
  • SAVVY (C31G) gel for prevention of HIV infection in women: a Phase 3, double-blind, randomized, placebo-controlled trial in Ghana. 
  • SAVVY vaginal gel (C31G) for prevention of HIV infection: a randomized controlled trial in Nigeria. 
  • Self-Assembling Peptide Gels for 3D Prostate Cancer Spheroid Culture. 
  • Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro. 
  • Silicone gel coating of a sutured flexor digital tendon within a sheath. 
  • Silver staining of histones in Triton-acid-urea gels. 
  • Soluble factor effects on glial cell reactivity at the surface of gel-coated microwires. 
  • Sonophoresis. I. The use of high-frequency ultrasound to enhance transdermal drug delivery. 
  • Spectrophotometric analysis of molecular transport in gels. 
  • Structure of the crystalline bilayer in the subgel phase of dipalmitoylphosphatidylglycerol. 
  • Studies of the ethanol-induced interdigitated gel phase in phosphatidylcholines using the fluorophore 1,6-diphenyl-1,3,5-hexatriene. 
  • Surface ripples cause the large fluid spaces between gel phase bilayers containing small amounts of cholesterol. 
  • Synchronized detection of minute electrical currents with MRI using Lorentz effect imaging. 
  • Temperature dependence of the repulsive pressure between phosphatidylcholine bilayers. 
  • Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells. 
  • The PESSRI study: symptom relief outcomes of a randomized crossover trial of the ring and Gellhorn pessaries. 
  • The origin of collagenase in periodontal tissues of man. 
  • The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention. 
  • The use of gradient flow compensation to separate diffusion and microcirculatory flow in MRI. 
  • Thermo-responsive systems for controlled drug delivery. 
  • Tissue-engineered bone formation with gene transfer and mesenchymal stem cells in a minimally invasive technique. 
  • Topical aminocaproic acid significantly reduces the incidence of secondary hemorrhage in traumatic hyphema in the rabbit model. 
  • Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%, gel in mycosis fungoides. 
  • Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. 
  • Tris buffer causes acyl chain interdigitation in phosphatidylglycerol. 
  • Two features at the two-dimensional freezing transitions. 
  • Ultrafast 1D MR thermometry using phase or frequency mapping. 
  • Use of hyaluronic acid gel in the treatment of lagophthalmos in sunken superior sulcus syndrome. 
  • Use of the 125I-labeled protein gel overlay technique to study calmodulin-binding proteins. 
  • Vaginal deployment and tenofovir delivery by microbicide gels. 
  • Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge. 
  • [BMP-2 gene carried by biodegradable scaffold and fibrinous gel for repairing segmental radial defect in rabbit]. 
  • pH-dependent conformational change of gastric mucin leads to sol-gel transition. 
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  Keywords of People

  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Craig, Stephen L, William T. Miller Distinguished Professor of Chemistry, Duke University Energy Initiative
  • Halabi, Susan, Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Katz, David F., Nello L. Teer, Jr. Distinguished Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering, Biomedical Engineering
  • Wax, Adam P., Professor of Biomedical Engineering, Biomedical Engineering