Gene Expression Regulation

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  Subject Areas on Research

  • "Good enough solutions" and the genetics of complex diseases. 
  • 2'Fluoro Modification Differentially Modulates the Ability of RNAs to Activate Pattern Recognition Receptors. 
  • 5' flanking sequences of the rat tyrosine hydroxylase gene target accurate tissue-specific, developmental, and transsynaptic expression in transgenic mice. 
  • 5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage. 
  • 9-cis retinoic acid regulation of rat growth hormone gene expression: potential roles of multiple nuclear hormone receptors. 
  • miR-146a -Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression. 
  • A CRISPR/Cas9-based system for reprogramming cell lineage specification. 
  • A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. 
  • A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. 
  • A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice. 
  • A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins. 
  • A bistable Rb-E2F switch underlies the restriction point. 
  • A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1. 
  • A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP. 
  • A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. 
  • A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. 
  • A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. 
  • A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. 
  • A centenarian-only approach for assessing gene-gene interaction in human longevity. 
  • A combinatorial mechanism for determining the specificity of E2F activation and repression. 
  • A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon. 
  • A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability. 
  • A comparative study of the distributions of renin and angiotensinogen messenger ribonucleic acids in rat and mouse tissues. 
  • A compendium of promoter-centered long-range chromatin interactions in the human genome. 
  • A compensatory base change in U1 snRNA suppresses a 5' splice site mutation. 
  • A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter. 
  • A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. 
  • A conserved sorting-associated protein is mutant in chorea-acanthocytosis. 
  • A conserved transcriptional enhancer regulates RAG gene expression in developing B cells. 
  • A constitutively active mutant beta 2-adrenergic receptor is constitutively desensitized and phosphorylated. 
  • A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression. 
  • A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells. 
  • A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity. 
  • A futile metabolic cycle activated in adipocytes by antidiabetic agents. 
  • A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells. 
  • A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function. 
  • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. 
  • A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. 
  • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. 
  • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. 
  • A meta-analysis of gene expression signatures of blood pressure and hypertension. 
  • A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium. 
  • A molecular mechanism for the differential regulation of TGF-beta1 expression due to the common SNP -509C-T (c. -1347C > T). 
  • A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes. 
  • A mouse homoeo box gene is expressed during embryogenesis and in adult kidney. 
  • A mouse model of adult-onset anaemia due to erythropoietin deficiency. 
  • A naturally occurring gamma globin gene mutation enhances SP1 binding activity. 
  • A new (heat) shocking player in cardiac hypertrophy. 
  • A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. 
  • A non-canonical start codon in the Drosophila fragile X gene yields two functional isoforms. 
  • A nonradioactive assay for transfected chloramphenicol acetyltransferase activity using fluorescent substrates. 
  • A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. 
  • A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation. 
  • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. 
  • A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC. 
  • A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. 
  • A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. 
  • A novel polypeptide secreted by activated human T lymphocytes. 
  • A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling. 
  • A novel role for XIAP in copper homeostasis through regulation of MURR1. 
  • A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. 
  • A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. 
  • A positive addition to a negative tail's tale. 
  • A potential role for Elf-1 in CD4 promoter function. 
  • A poxvirus-derived vector that directs high levels of expression of cloned genes in mammalian cells. 
  • A rapid and simple procedure for the preparation of homogeneously labeled DNA probes. 
  • A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. 
  • A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy. 
  • A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. 
  • A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. 
  • A role for Sfrp2 in cardiomyogenesis in vivo. 
  • A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. 
  • A role for ΔFosB in calorie restriction-induced metabolic changes. 
  • A role of the CTCF binding site at enhancer Eα in the dynamic chromatin organization of the Tcra-Tcrd locus. 
  • A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged. 
  • A single tube, four-color flow cytometry assay for evaluation of ZAP-70 and CD38 expression in chronic lymphocytic leukemia. 
  • A small-molecule antagonist of the hedgehog signaling pathway. 
  • A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression. 
  • A threshold for central T cell tolerance to an inducible serum protein 
  • A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells. 
  • A tissue-engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling. 
  • A transcription factor affinity-based code for mammalian transcription initiation. 
  • A transforming growth factor beta type I receptor that signals to activate gene expression. 
  • A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis. 
  • A unique role of the DNA fragmentation factor in maintaining genomic stability. 
  • A user's guide to the encyclopedia of DNA elements (ENCODE). 
  • A viral microRNA functions as an orthologue of cellular miR-155. 
  • A whole-genome analysis of premature termination codons. 
  • A yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters. 
  • A20 modulates lipid metabolism and energy production to promote liver regeneration. 
  • A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. 
  • ADAM10 is essential for proteolytic activation of Notch during thymocyte development. 
  • ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression. 
  • AP-1 subunits converge promiscuously at enhancers to potentiate transcription. 
  • APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. 
  • APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. 
  • ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes. 
  • Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. 
  • Aberrant activation of signal transducer and activator of transcription-3 (STAT3) signaling in endometriosis. 
  • Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. 
  • Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages. 
  • Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload. 
  • Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. 
  • Accelerated neural differentiation of mouse embryonic stem cells on aligned GYIGSR-functionalized nanofibers. 
  • Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. 
  • Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease. 
  • Acetylation takes aim at mRNA. 
  • Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1. 
  • Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine. 
  • Activation and repression of mammalian gene expression by the c-myc protein. 
  • Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation. 
  • Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells. 
  • Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth. 
  • Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy. 
  • Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease. 
  • Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge to MEK1/ERK2 and activate the Elk1 transcription factor. 
  • Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117. 
  • Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice. 
  • Activity-Dependent Transcription Collaborates with Local Dendritic Translation to Encode Stimulus-Specificity in the Genome Binding of NPAS4. 
  • Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. 
  • Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons. 
  • Acute brain death alters left ventricular myocardial gene expression. 
  • Adaptation of skeletal muscle to increased contractile activity. Expression nuclear genes encoding mitochondrial proteins. 
  • Adaptive Transcriptome Profiling of Subterranean Zokor, Myospalax baileyi, to High- Altitude Stresses in Tibet. 
  • Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. 
  • Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism. 
  • Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease. 
  • Adipocytes. 
  • Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus. 
  • Advances to Bayesian network inference for generating causal networks from observational biological data. 
  • Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans. 
  • Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy. 
  • Allele-specific distribution of RNA polymerase II on female X chromosomes. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Allelic exclusion of the T cell receptor alpha-chain: developmental regulation of a post-translational event. 
  • Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl. 
  • Allosteric effects of external K+ ions mediated by the aspartate of the GYGD signature sequence in the Kv2.1 K+ channel. 
  • Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch. 
  • Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements. 
  • Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway. 
  • Alteration of Caenorhabditis elegans gene expression by targeted transformation. 
  • Alterations in TNF- and IL-related gene expression in space-flown WI38 human fibroblasts. 
  • Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. 
  • Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis. 
  • Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. 
  • Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts. 
  • Altered levels of prothymosin immunoreactive peptide, a growth-related gene product, during liver regeneration after chronic ethanol feeding. 
  • Altered lymphopoiesis and immunodeficiency in miR-142 null mice. 
  • Altered sodium regulation of renal angiotensinogen mRNA in the spontaneously hypertensive rat. 
  • Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. 
  • Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. 
  • Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy. 
  • Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev. 
  • An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents. 
  • An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. 
  • An Optogenetic Method to Study Signal Transduction in Intestinal Stem Cell Homeostasis. 
  • An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus. 
  • An analysis of alternatively spliced CD45 mRNA transcripts during T cell maturation in humans. 
  • An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development. 
  • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. 
  • An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia. 
  • An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. 
  • An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau. 
  • An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro. 
  • Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation. 
  • Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. 
  • Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration. 
  • Analysis of the individual regulatory components of the IncFII plasmid replication control system. 
  • Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts. 
  • Ancient and recent positive selection transformed opioid cis-regulation in humans. 
  • Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. 
  • Angiopoietin-1 enhances skeletal muscle regeneration in mice. 
  • Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. 
  • Angiotensin II induces c-fos expression in smooth muscle via transcriptional control. 
  • Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium. 
  • Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease. 
  • Annotating nonspecific SAGE tags with microarray data. 
  • Anti-fibrotic effects of different sources of MSC in bleomycin-induced lung fibrosis in C57BL6 male mice. 
  • Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. 
  • Antibodies to stem cell marker antigens reduce engraftment of hematopoietic stem cells. 
  • Antibody formation and mannose-6-phosphate receptor expression impact the efficacy of muscle-specific transgene expression in murine Pompe disease. 
  • Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. 
  • Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. 
  • Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay. 
  • Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7. 
  • Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection. 
  • Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. 
  • Apolipoprotein E isotype-dependent modulation of microRNA-146a in plasma and brain. 
  • Apolipoprotein J/clusterin induction in myocarditis: A localized response gene to myocardial injury. 
  • ApolipoproteinE mimetic peptides improve outcome after focal ischemia. 
  • Apoptosis rate can be accelerated or decelerated by overexpression or reduction of the level of elongation factor-1 alpha. 
  • Applications of a rat multiple tissue gene expression data set. 
  • Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver. 
  • Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement. 
  • Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects. 
  • Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways. 
  • Ascorbic acid modulates collagen type I gene expression by cells from an eye tissue--trabecular meshwork. 
  • Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology. 
  • Assessment of candidate ocular biomarkers of ageing in a South African adult population: relationship with chronological age and systemic biomarkers. 
  • Assessment of gene expression in peripheral blood using RNAseq before and after weight restoration in anorexia nervosa. 
  • Assessment of the immune capacity of mammary epithelial cells: comparison with mammary tissue after challenge with Escherichia coli. 
  • Association of misexpression with sterility in hybrids of Drosophila simulansand D. mauritiana. 
  • Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function. 
  • Associative learning and stimulus novelty influence the song-induced expression of an immediate early gene in the canary forebrain. 
  • Atherosclerosis and cancer: common molecular pathways of disease development and progression. 
  • Atomic description of the immune complex involved in heparin-induced thrombocytopenia. 
  • Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. 
  • Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. 
  • Axonal Odorant Receptors Mediate Axon Targeting. 
  • B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin. 
  • B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis. 
  • B1 and TRPV-1 receptor genes and their relationship to hyperalgesia following spinal cord injury. 
  • BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis. 
  • BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. 
  • BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene. 
  • BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication. 
  • BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. 
  • Baby Genomics: Tracing the Evolutionary Changes That Gave Rise to Placentation. 
  • Bacterial expression and characterization of proteins derived from the chicken calmodulin cDNA and a calmodulin processed gene. 
  • Bacterial infection remodels the DNA methylation landscape of human dendritic cells. 
  • Bacterial-induced cell fusion is a danger signal triggering cGAS-STING pathway via micronuclei formation. 
  • Balancing acts: molecular control of mammalian iron metabolism. 
  • Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial. 
  • Bayesian analysis of signaling networks governing embryonic stem cell fate decisions. 
  • Bayesian joint analysis of heterogeneous genomics data. 
  • Behaviourally driven gene expression reveals song nuclei in hummingbird brain. 
  • Benchmarking of dynamic Bayesian networks inferred from stochastic time-series data. 
  • Beryllium fluoride-induced cell proliferation: a process requiring P21(ras)-dependent activated signal transduction and NF-kappaB-dependent gene regulation. 
  • Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids. 
  • Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing. 
  • Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing. 
  • Beta-thalassemia resulting from a single nucleotide substitution in an acceptor splice site. 
  • Beyond intuitive modeling: combining biophysical models with innovative experiments to move the circadian clock field forward. 
  • Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. 
  • Biochemical and biomechanical characteristics of dystrophin-deficient mdx3cv mouse lens. 
  • Biochemical mechanisms of hormone receptor-effector coupling. Introduction. 
  • Biochemistry. A glucose-to-gene link. 
  • Biological and analytical stability of a peripheral blood gene expression score for obstructive coronary artery disease in the PREDICT and COMPASS studies. 
  • Biological clocks and the coordination theory of RNA operons and regulons. 
  • Biphasic induction of immediate early gene expression accompanies activity-dependent angiogenesis and myofiber remodeling of rabbit skeletal muscle. 
  • Bleomycin induces the hsp 70 heat shock promoter in cultured cells. 
  • Blood pressure homeostasis is maintained by a P311-TGF-β axis. 
  • Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. 
  • Blurring the edges in vertebrate sex determination. 
  • Body size determination in insects: a review and synthesis of size- and brain-dependent and independent mechanisms. 
  • Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions. 
  • Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy. 
  • Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. 
  • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. 
  • Brain gene regulation by territorial singing behavior in freely ranging songbirds. 
  • Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo. 
  • Broadening primate genomics: new insights into the ecology and evolution of primate gene regulation. 
  • C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling. 
  • CARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomes. 
  • CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts. 
  • CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. 
  • CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells. 
  • CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice. 
  • CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway. 
  • CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells. 
  • CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation. 
  • CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression. 
  • CD22: a multifunctional receptor that regulates B lymphocyte survival and signal transduction. 
  • CD25+CD4+ regulatory T cell migration requires L-selectin expression: L-selectin transcriptional regulation balances constitutive receptor turnover. 
  • CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. 
  • CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis. 
  • CD8+ T-cell alveolitis in familial pulmonary alveolar microlithiasis. 
  • CDK5 regulates cell adhesion and migration in corneal epithelial cells. 
  • COMT gene locus: new functional variants. 
  • COPD: balancing oxidants and antioxidants. 
  • COUP-TFII regulates human endometrial stromal genes involved in inflammation. 
  • CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability. 
  • CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. 
  • CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis. 
  • CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis. 
  • Ca(2+)/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix. 
  • Ca2+/calmodulin-dependent protein kinase IV and calcium signaling. 
  • Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. 
  • Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. 
  • Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology. 
  • Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility. 
  • Calcineurin signaling and muscle remodeling. 
  • Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction. 
  • Calcineurin. Structure, function, and inhibition. 
  • Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling. 
  • Calcium regulation of neuronal gene expression. 
  • Calcium, calmodulin and cell proliferation. 
  • Calcium-dependent gene regulation in myocyte hypertrophy and remodeling. 
  • Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology. 
  • Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. 
  • Calmodulin as a regulator of cell growth and gene expression. 
  • Calmodulin is required for cell-cycle progression during G1 and mitosis. 
  • Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. 
  • Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene. 
  • Candidate genes mediating magnetoreception in rainbow trout (Oncorhynchus mykiss). 
  • Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans. 
  • Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice. 
  • Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway. 
  • Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells. 
  • Cardiac myocyte p38α kinase regulates angiogenesis via myocyte-endothelial cell cross-talk during stress-induced remodeling in the heart. 
  • Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. 
  • Cartilage tumours and bone development: molecular pathology and possible therapeutic targets. 
  • Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. 
  • Cathepsin B is up-regulated and mediates extracellular matrix degradation in trabecular meshwork cells following phagocytic challenge. 
  • Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. 
  • Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. 
  • Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. 
  • Cell cycle regulation of human pancreatic cancer by tamoxifen. 
  • Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity. 
  • Cell cycle-dependent regulation of smooth muscle cell activation. 
  • Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010. 
  • Cell surface expression of major histocompatibility class I antigens is modulated by P-glycoprotein transporter. 
  • Cell type-specific effects of Notch signaling activation on intervertebral discs: Implications for intervertebral disc degeneration. 
  • Cell-Type-Specific Analysis of Molecular Pathology in Autism Identifies Common Genes and Pathways Affected Across Neocortical Regions. 
  • Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency. 
  • Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption. 
  • Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells. 
  • Cell-type specific regulation of gene expression by simian virus 40 T antigens. 
  • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. 
  • Cellular arrays for large-scale analysis of transcription factor activity. 
  • Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen. 
  • Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition. 
  • Cervical Expression of Elafin and SLPI in Pregnancy and Their Association With Preterm Labor. 
  • Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model. 
  • Changes in serum leptin levels as well as sICAM-1 and sVCAM-1 soluble adhesion molecules during carotid endarterectomy. 
  • Changes in sphingomyelinases, ceramide, Bax, Bcl(2), and caspase-3 during and after experimental status epilepticus. 
  • Characterization of COMMD protein-protein interactions in NF-kappaB signalling. 
  • Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation. 
  • Characterization of Langerin-expressing dendritic cell subsets in the normal cornea. 
  • Characterization of a putative insulin-responsive element and its binding protein(s) in rat angiotensinogen gene promoter: regulation by glucose and insulin. 
  • Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy. 
  • Characterization of a zinc finger DNA-binding protein expressed specifically in Petunia petals and seedlings. 
  • Characterization of cis-regulatory elements controlling repo transcription in Drosophila melanogaster. 
  • Characterization of human Gadd45, a p53-regulated protein. 
  • Characterization of human prorenin expressed in mammalian cells from cloned cDNA. 
  • Characterizing differences between MSCs and TM cells: Toward autologous stem cell therapies for the glaucomatous trabecular meshwork. 
  • Chemoattractant-induced activation of c-fos gene expression in human monocytes. 
  • Cholinergic receptor subtypes in the olfactory bulbectomy model of depression. 
  • Chromatin signatures of the Drosophila replication program. 
  • Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signaling. 
  • Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. 
  • Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression. 
  • Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion. 
  • Circular RNA RSF1 promotes inflammatory and fibrotic phenotypes of irradiated hepatic stellate cell by modulating miR-146a-5p. 
  • Circular RNAs are abundant, conserved, and associated with ALU repeats. 
  • Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration. 
  • Cloning and developmental expression of the chick type II and type III TGF beta receptors. 
  • Cloning genes that encode drug-metabolizing enzymes: developmental pharmacology and teratology. 
  • Cloning of DNA corresponding to rare transcripts of rat brain: evidence of transcriptional and post-transcriptional control and of the existence of nonpolyadenylated transcripts. 
  • Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family. 
  • Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. 
  • Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. 
  • Co-expression of nAChRs and molecules of the bitter taste transduction pathway by epithelial cells of intrapulmonary airways. 
  • Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens. 
  • Codon usage regulates human KRAS expression at both transcriptional and translational levels. 
  • Collaborative interactions between MEF-2 and Sp1 in muscle-specific gene regulation. 
  • Combination anti-CD2 and anti-CD3 monoclonal antibodies induce tolerance while altering interleukin-2, interleukin-4, tumor necrosis factor, and transforming growth factor-beta production. 
  • Combination antiretroviral therapy results in a rapid increase in T cell receptor variable region beta repertoire diversity within CD45RA CD8 T cells in human immunodeficiency virus-infected children. 
  • Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. 
  • Combinatorial and synergistic properties of CaMV 35S enhancer subdomains. 
  • Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons. 
  • Combined immunodeficiency due to the selective absence of CD4 inducer T lymphocytes. 
  • Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression. 
  • Commensal Bacteria Regulate Gene Expression and Differentiation in Vertebrate Olfactory Systems Through Transcription Factor REST. 
  • Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee. 
  • Comparative analysis of behavioral and transcriptional variation underlying CO₂ sensory neuron function and development in Drosophila. 
  • Comparative analysis reveals distinctive epigenetic features of the human cerebellum. 
  • Comparative genomics of mammalian hibernators using gene networks. 
  • Comparison of gene expression profiles induced by coarse, fine, and ultrafine particulate matter. 
  • Competitive displacement of phosphoinositide 3-kinase from beta-adrenergic receptor kinase-1 improves postinfarction adverse myocardial remodeling. 
  • Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses. 
  • Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells. 
  • Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene. 
  • Complex regulation of human c-kit transcription by promoter repressors, activators, and specific myb elements. 
  • Complex relationships of nicotinic receptor actions and cognitive functions. 
  • Complex structure and regulation of the ABP/SHBG gene. 
  • Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys. 
  • Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. 
  • Comprehensive functional genomic resource and integrative model for the human brain. 
  • Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. 
  • Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. 
  • Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation. 
  • Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. 
  • Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations. 
  • Constitutive activation of the aromatic hydrocarbon receptor. 
  • Constitutive expression of placental lactogen in pancreatic beta cells: effects on cell morphology, growth, and gene expression. 
  • Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features. 
  • Consumption of a high-fat diet induces central insulin resistance independent of adiposity. 
  • Continuous Culture of Mouse Primary B Lymphocytes by Forced Expression of Bach2. 
  • Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle. 
  • Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis. 
  • Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys. 
  • Control of electrolyte balance through ubiquitination. 
  • Control of fibroblast senescence and activation of programmed cell death. 
  • Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions. 
  • Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. 
  • Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion. 
  • Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling. 
  • Convergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learners. 
  • Convergent differential regulation of parvalbumin in the brains of vocal learners. 
  • Convergent transcriptional specializations in the brains of humans and song-learning birds. 
  • Cooperation among multiple transcription factors is required for access to minimal T-cell receptor alpha-enhancer chromatin in vivo. 
  • Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. 
  • Coordinate regulation of mRNAs from multiple calmodulin genes during myoblast differentiation in vitro. 
  • Coordinated activation of corneal wound response genes in vivo as observed by in situ hybridization. 
  • Coordinated posttranscriptional mRNA population dynamics during T-cell activation. 
  • Coordinating expression of RNA binding proteins with their mRNA targets. 
  • Copy number variation is associated with gene expression change in archaea. 
  • Core and region-enriched networks of behaviorally regulated genes and the singing genome. 
  • Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides. 
  • Correlation of peripheral-blood gene expression with the extent of coronary artery stenosis. 
  • Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. 
  • Coupling fibroblast growth factor 23 production and cleavage: iron deficiency, rickets, and kidney disease. 
  • Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-kappaB activation. 
  • Cowpox virus induces interleukin-10 both in vitro and in vivo. 
  • Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. 
  • Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. 
  • Critical role of TNF-α in cerebral aneurysm formation and progression to rupture. 
  • Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues. 
  • Cross-platform prediction of gene expression signatures. 
  • Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes. 
  • Cutting edge: TGF-beta-induced expression of Foxp3 in T cells is mediated through inactivation of ERK. 
  • Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation. 
  • Cyclic regulation of transcription factor C/EBP beta in human endometrium. 
  • Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation. 
  • Cytokine regulation of liver injury and repair. 
  • Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells. 
  • Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor. 
  • Cytoplasmic polyadenylation element binding protein deficiency stimulates PTEN and Stat3 mRNA translation and induces hepatic insulin resistance. 
  • DIO2 modifies inflammatory responses in chondrocytes. 
  • DNA and RNA topoisomerase activities of Top3β are promoted by mediator protein Tudor domain-containing protein 3. 
  • DNA damage responses: p53 induction, cell cycle perturbations, and apoptosis. 
  • DNA fragments from F9 PyEC mutants increase expression of heterologous genes in transfected F9 cells. 
  • DNA methylation in epigenetic control of gene expression. 
  • DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes. 
  • DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection. 
  • DNA repair and epidemiology of basal cell carcinoma. 
  • DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor. 
  • DNase I sensitivity QTLs are a major determinant of human expression variation. 
  • Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice. 
  • De novo transcriptomics reveal distinct phototransduction signaling components in the retina and skin of a color-changing vertebrate, the hogfish (Lachnolaimus maximus). 
  • Deciphering the molecular machinery of stem cells: a look at the neoblast gene expression profile. 
  • Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity. 
  • Decoding the noncoding transcripts in human heart failure. 
  • Decoding the role of regulatory element polymorphisms in complex disease. 
  • Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells. 
  • Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity. 
  • Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. 
  • Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M. 
  • Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. 
  • Defective pericyte recruitment of villous stromal vessels as the possible etiologic cause of hydropic change in complete hydatidiform mole. 
  • Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IV. 
  • Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. 
  • Defining Ca2+/calmodulin-dependent protein kinase cascades in transcriptional regulation. 
  • Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy. 
  • Defining the human macula transcriptome and candidate retinal disease genes using EyeSAGE. 
  • Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor. 
  • Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation. 
  • Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription. 
  • Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. 
  • Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia. 
  • Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. 
  • Dengue virus-induced autophagy regulates lipid metabolism. 
  • Dependence of corneal stem/progenitor cells on ocular surface innervation. 
  • Depressed expression of adipocyte beta-adrenergic receptors is a common feature of congenital and diet-induced obesity in rodents. 
  • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. 
  • Design and Analysis of Large-Scale Biological Rhythm Studies: A Comparison of Algorithms for Detecting Periodic Signals in Biological Data 
  • Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle. 
  • Detailed analysis of gene expression during development of T cell lineages in the thymus. 
  • Detecting and characterizing circular RNAs. 
  • Detecting m6A with In Vitro DART-Seq. 
  • Detection of differentially abundant cell subpopulations in scRNA-seq data. 
  • Detection of inducible clindamycin resistance in staphylococci by broth microdilution using erythromycin-clindamycin combination wells. 
  • Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients. 
  • Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials. 
  • Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated. 
  • Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1. 
  • Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance. 
  • Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. 
  • Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel. 
  • Developmental regulation of calmodulin, actin, and tubulin RNAs during rat testis differentiation. 
  • Developmental regulation of mouse SPARC (osteonectin) gene expression. 
  • Developmentally regulated expression of two members of the Nrarp family in zebrafish. 
  • Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice. 
  • Dietary CdSe/ZnS quantum dot exposure in estuarine fish: bioavailability, oxidative stress responses, reproduction, and maternal transfer. 
  • Dietary regulation of glucose-dependent insulinotropic peptide (GIP) gene expression in rat small intestine. 
  • Dietary regulation of rat intestinal cholecystokinin gene expression. 
  • Differences in the anatomic distribution of immediate-early gene expression in amygdala and angular bundle kindling development. 
  • Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia. 
  • Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-Affected Corneas. 
  • Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression. 
  • Differential biomarker gene and protein expressions in nonylphenol and estradiol-17beta treated juvenile rainbow trout (Oncorhynchus mykiss). 
  • Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis? 
  • Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus. 
  • Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. 
  • Differential effects of vitamin d receptor agonists on gene expression in neonatal rat cardiomyocytes. 
  • Differential expression of S1 and elongation factor-1 alpha during rat development. 
  • Differential expression of galectin-1 and its interactions with cells and laminins in the intervertebral disc. 
  • Differential expression of gamma-aminobutyric acidA receptor subunits. 
  • Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. 
  • Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy. 
  • Differential expression of plasminogen activators and their inhibitors in an organotypic skin coculture system. 
  • Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells. 
  • Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes. 
  • Differential gene expression and genomic patient stratification following left ventricular assist device support. 
  • Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosis. 
  • Differential gene expression in mouse sclera during ocular development. 
  • Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia. 
  • Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. 
  • Differential modulation of Th1- and Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein. 
  • Differential modulation of gene induction by glucocorticoids and antiglucocorticoids in rat hepatoma tissue culture cells. 
  • Differential molecular mechanism of the estrogen action that regulates lactoferrin gene in human and mouse. 
  • Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens. 
  • Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. 
  • Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells. 
  • Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression. 
  • Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma. 
  • Direct regulation of beta3-integrin subunit gene expression by HOXA10 in endometrial cells. 
  • Direct visualization of cardiac transcription factories reveals regulatory principles of nuclear architecture during pathological remodeling. 
  • Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers. 
  • Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo. 
  • Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. 
  • Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells. 
  • Disease-Specific Expression of Conjunctiva Associated Lymphoid Tissue (CALT) in Mouse Models of Dry Eye Disease and Ocular Allergy. 
  • Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity. 
  • Disruption of sarcoendoplasmic reticulum calcium ATPase function in Drosophila leads to cardiac dysfunction. 
  • Dissection of genetic pathways in C. elegans. 
  • Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. 
  • Distinct and histone-specific modifications mediate positive versus negative transcriptional regulation of TSHalpha promoter. 
  • Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation. 
  • Distinct functions of two isoforms of a homeobox gene, BP1 and DLX7, in the regulation of the beta-globin gene. 
  • Distinct gene expression phenotypes of cells lacking Rb and Rb family members. 
  • Distinct gene expression profiles in adult mouse heart following targeted MAP kinase activation. 
  • Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator. 
  • Distinct properties of cell-type-specific and shared transcription factor binding sites. 
  • Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. 
  • Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. 
  • Distinctions in the specificity of E2F function revealed by gene expression signatures. 
  • Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest. 
  • Divergence in DNA Specificity among Paralogous Transcription Factors Contributes to Their Differential In Vivo Binding. 
  • Divergence in problem-solving skills is associated with differential expression of glutamate receptors in wild finches. 
  • Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. 
  • Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells. 
  • Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. 
  • Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation. 
  • Donor-specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population. 
  • Dopamine D1 receptors and phosphorylation of dopamine- and cyclic AMP-regulated phosphoprotein-32 in the medial preoptic area are involved in experience-induced enhancement of male sexual behavior in rats. 
  • Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation. 
  • Downregulation of RNA polymerase III transcription of the hY3 gene in vitro. 
  • Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD. 
  • Downregulation of the AU-rich RNA-binding protein ZFP36 in chronic HBV patients: implications for anti-inflammatory therapy. 
  • Drebrin-like protein DBN-1 is a sarcomere component that stabilizes actin filaments during muscle contraction. 
  • Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures. 
  • Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. 
  • Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair. 
  • Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis. 
  • Dynamic DNA methylation across diverse human cell lines and tissues. 
  • Dynamic and redundant regulation of LRRK2 and LRRK1 expression. 
  • Dynamic contrast-enhanced MRI promotes early detection of toxin-induced acute kidney injury. 
  • Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia. 
  • Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. 
  • Dysregulation of WTI (-KTS) is Associated with the Kidney-Specific Effects of the LMX1B R246Q Mutation. 
  • Dysregulation of hedgehog signalling predisposes to synovial chondromatosis. 
  • E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins. 
  • E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. 
  • ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. 
  • ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. 
  • ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha. 
  • EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs. 
  • Early Endometriosis in Females Is Directed by Immune-Mediated Estrogen Receptor α and IL-6 Cross-Talk. 
  • Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint. 
  • Early onset preeclampsia in a model for human placental trophoblast. 
  • Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. 
  • Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. 
  • Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. 
  • Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. 
  • Editing the Epigenome: Reshaping the Genomic Landscape. 
  • Editing the epigenome: technologies for programmable transcription and epigenetic modulation. 
  • Editorial: studying hormonal regulation by microarrays: distinguishing the trees from the forest. 
  • Effect of Alemtuzumab (CAMPATH 1-H) in patients with inclusion-body myositis. 
  • Effect of CXCL-1/KC production in high risk vascularized corneal allografts on T cell recruitment and graft rejection. 
  • Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes. 
  • Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system. 
  • Effect of cyclic stretch on beta1D-integrin expression and activation of FAK and RhoA. 
  • Effect of ethanol on tumor necrosis factor signaling during liver regeneration. 
  • Effect of influenza virus vaccine on the expression of human immunodeficiency virus co-receptor CCR5. 
  • Effect of intracerebroventricular infusion of insulin on glucose-dependent insulinotropic peptide in dogs. 
  • Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors. 
  • Effects of Combined Tristetraprolin/Tumor Necrosis Factor Receptor Deficiency on the Splenic Transcriptome. 
  • Effects of Space Flight on Mouse Liver versus Kidney: Gene Pathway Analyses. 
  • Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors. 
  • Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-α, IL-1β, and IFN-γ. 
  • Effects of chronic ethanol consumption on cytokine regulation of liver regeneration. 
  • Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice. 
  • Effects of inhibition of mitochondrial protein synthesis in skeletal muscle. 
  • Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. 
  • Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. 
  • Effects of spaceflight on murine skeletal muscle gene expression. 
  • Effects of temperature acclimation on Pacific bluefin tuna (Thunnus orientalis) cardiac transcriptome. 
  • Efficacy of an adeno-associated virus 8-pseudotyped vector in glycogen storage disease type II. 
  • Efficacy of gene therapy for a prototypical lysosomal storage disease (GSD-II) is critically dependent on vector dose, transgene promoter, and the tissues targeted for vector transduction. 
  • Efficient dendritic cell priming of T lymphocytes depends on the extracellular matrix protein mindin. 
  • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. 
  • Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene. 
  • Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering. 
  • Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers. 
  • Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: soluble L-selectin levels indicate disease severity. 
  • Elevations of FosB in the nucleus accumbens during forced cocaine abstinence correlate with divergent changes in reward function. 
  • Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration. 
  • Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and CYP1A inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus). 
  • Embryonic germ cells are capable of adipogenic differentiation in vitro and in vivo. 
  • Emerging clinical applications of RNA. 
  • Endogenous avian retroviruses contain deficient promoter and leader sequences. 
  • Endogenous lung stem cells and contribution to disease. 
  • Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. 
  • Endothelial cell diversity revealed by global expression profiling. 
  • Endothelin-1 induces an increase in total protein synthesis and expression of the smooth muscle alpha-actin gene in vascular smooth muscle cells. 
  • Endotoxin and NO induce MIP-1gamma gene transcription in ANA-1 murine macrophages. 
  • Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages. 
  • Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. 
  • Engineering musculoskeletal tissues with human embryonic germ cell derivatives. 
  • Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression. 
  • Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor. 
  • Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain. 
  • Enhanced central response to dehydration in mice lacking angiotensin AT(1a) receptors. 
  • Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells. 
  • Enhanced vasorelaxation by overexpression of beta 2-adrenergic receptors in large arteries. 
  • Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery. 
  • Enhancement of rAAV2-mediated transgene expression in retina cells in vitro and in vivo by coadministration of low-dose chemotherapeutic drugs. 
  • Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. 
  • Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems. 
  • Enhancer selection dictates gene expression responses in remote organs during tissue regeneration. 
  • Enhancer-blocking activity within the DNase I hypersensitive site 2 to 6 region between the TCR alpha and Dad1 genes. 
  • Environmental factors in relation to breast cancer characterized by p53 protein expression. 
  • Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC). 
  • Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders. 
  • Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. 
  • Epigenetic regulation of COL15A1 in smooth muscle cell replicative aging and atherosclerosis. 
  • Epigenome editing of the CFTR-locus for treatment of cystic fibrosis. 
  • Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. 
  • Epigenomic links from metabolism-methionine and chromatin architecture. 
  • Epithelial invasion by Escherichia coli bearing Dr fimbriae is controlled by nitric oxide-regulated expression of CD55. 
  • Erythrocyte invasion profiles are associated with a common invasion ligand polymorphism in Senegalese isolates of Plasmodium falciparum. 
  • Erythroid transcription factor NF-E2 coordinates hemoglobin synthesis. 
  • Erythropoietin mediates terminal granulocytic differentiation of committed myeloid cells with ectopic erythropoietin receptor expression. 
  • Erythropoietin receptor signals both proliferation and erythroid-specific differentiation. 
  • Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation. 
  • Estradiol regulates MICA expression in human endometrial cells. 
  • Estrogen and thyroid hormone interaction on regulation of gene expression. 
  • Estrogen receptor interconversion, factors regulating conformation and functions. 
  • Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women. 
  • Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity. 
  • Estrogens and prostate cancer. 
  • Eukaryotic mRNPs may represent posttranscriptional operons. 
  • Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III. 
  • Evaluating functional network inference using simulations of complex biological systems. 
  • Evaluation of CD86/CD28 and CD40/CD154 pathways in regulating monocyte-derived CD80 expression during their interaction with allogeneic endothelium. 
  • Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]. 
  • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. 
  • Evolution of a malaria resistance gene in wild primates. 
  • Evolution. CNCing is believing. 
  • Evolution. Chaperones as buffering agents? 
  • Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons. 
  • Exercise training increases electron and substrate shuttling proteins in muscle of overweight men and women with the metabolic syndrome. 
  • Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. 
  • Explicit equilibrium modeling of transcription-factor binding and gene regulation. 
  • Exploiting expression patterns across multiple tissues to map expression quantitative trait loci. 
  • Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily. 
  • Expression analysis of the matrix GLA protein and VE-cadherin gene promoters in the outflow pathway. 
  • Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel. 
  • Expression and hormonal regulation of coactivator and corepressor genes. 
  • Expression and modulation of RPE cell membrane complement regulatory proteins. 
  • Expression and production of interleukin-10 by human trophoblast: relationship to pregnancy immunotolerance. 
  • Expression and regulation of alpha 1-adrenergic receptors in human tissues. 
  • Expression and sequence analysis of a cDNA encoding the orotidine-5'-monophosphate decarboxylase domain from Ehrlich ascites uridylate synthase. 
  • Expression and trafficking of placental microRNAs at the feto-maternal interface. 
  • Expression in aneuploid Drosophila S2 cells. 
  • Expression microarray identifies novel markers of free flap failure in a rat model. 
  • Expression of HSP70 in peripheral lymphocytes of the patients with allergic rhinitis. 
  • Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression. 
  • Expression of RNAs for calmodulin, actins, and tubulins in rat testis cells. 
  • Expression of TGF-beta-related genes during mouse embryo whisker morphogenesis. 
  • Expression of TIMP in fetal and adult mouse tissues studied by in situ hybridization. 
  • Expression of a cloned human interleukin-2 cDNA is enhanced by the substitution of a heterologous mRNA leader region. 
  • Expression of antimicrobial peptides in the normal and involved skin of patients with infective cellulitis. 
  • Expression of differentiation antigens by hybrids of human lymphoblastoid cells. 
  • Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae). 
  • Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture. 
  • Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. 
  • Expression of major histocompatibility complex class I antigens in normal and transformed rat thyroid epithelial cell lines. 
  • Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of polyoma early gene products in E. coli. 
  • Expression of rRNA and tRNA genes in Escherichia coli: evidence for feedback regulation by products of rRNA operons. 
  • Expression of socially sensitive genes: The multi-ethnic study of atherosclerosis. 
  • Expression of surface CD1d in the extravillous trophoblast cells of early gestational placenta is downregulated in a manner dependent on trophoblast differentiation. 
  • Expression of the 71 kDa dystrophin isoform (Dp71) evaluated by gene targeting. 
  • Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. 
  • Expression of the homeobox gene, Hox 2.1, during mouse embryogenesis. 
  • Expression of the homeobox genes Hox 2.1 and 2.6 during mouse development. 
  • Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog. 
  • Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines. 
  • Expression of the type III TGF-beta receptor is negatively regulated by TGF-beta. 
  • Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells. 
  • Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection. 
  • Expression quantitative trait locus analysis identifies novel genes for statin myopathy. 
  • Extensive changes in the expression of the opioid genes between humans and chimpanzees. 
  • Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection. 
  • Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element. 
  • Extracellular vesicles from endometriosis patients are characterized by a unique miRNA-lncRNA signature. 
  • Extrarenal Signs of Proximal Renal Tubular Acidosis Persist in Nonacidemic Nbce1b/c-Null Mice. 
  • FACS analysis of neuronal-glial interactions in the nucleus accumbens following morphine administration. 
  • FKBP12 is not required for the modulation of transforming growth factor beta receptor I signaling activity in embryonic fibroblasts and thymocytes. 
  • FMRP targets distinct mRNA sequence elements to regulate protein expression. 
  • FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans. 
  • FOXO protects against age-progressive axonal degeneration. 
  • FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. 
  • FTO Suppresses STAT3 Activation and Modulates Proinflammatory Interferon-Stimulated Gene Expression. 
  • Factors regulating islet regeneration in the post-insulinoma NEDH rat. 
  • Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. 
  • Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. 
  • Fibronectin-integrin signaling is required for L-glutamine's protection against gut injury. 
  • Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse. 
  • Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process. 
  • Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis. 
  • Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis 
  • Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium. 
  • Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade. 
  • Focal expression of mutant huntingtin in the songbird basal ganglia disrupts cortico-basal ganglia networks and vocal sequences. 
  • Focal gene induction in the liver of rats by a heat-inducible promoter using focused ultrasound hyperthermia: preliminary results. 
  • For whom the bird sings: context-dependent gene expression. 
  • Formation of supercoiling domains in plasmid pBR322. 
  • FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. 
  • Frequency-dependent response of the vascular endothelium to pulsatile shear stress. 
  • From induction to conduction: how intrinsic transcriptional priming of extrinsic neuronal connectivity shapes neuronal identity. 
  • Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways. 
  • Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling. 
  • Functional Characteristics and Phenotypic Plasticity of CD57+PD1- CD4 T Cells and Their Relationship with Transplant Immunosuppression. 
  • Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. 
  • Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region. 
  • Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation. 
  • Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function. 
  • Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. 
  • Functional expression of Mammalian odorant receptors. 
  • Functional expression of an arachnid sodium channel reveals residues responsible for tetrodotoxin resistance in invertebrate sodium channels. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. 
  • Functional human renin promoter in transfected cells: evidence for cell-specific expression. 
  • Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein. 
  • Further characterization of erythrocyte p80 and the membrane protein defect of In(Lu) Lu(a-b-) erythrocytes. 
  • G protein-coupled estrogen receptor (GPER) expression in normal and abnormal endometrium. 
  • G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy. 
  • G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. 
  • G-CSF induces a potentially tolerant gene and immunophenotype profile in T cells in vivo. 
  • G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons. 
  • GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts. 
  • GATA4 and the two sides of gene expression reprogramming. 
  • GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans. 
  • GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats. 
  • GLUTAMINE PREVENTS ACTIVATION OF NF-kappaB AND STRESS KINASE PATHWAYS, ATTENUATES INFLAMMATORY CYTOKINE RELEASE, AND PREVENTS ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FOLLOWING SEPSIS. 
  • GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. 
  • GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. 
  • Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. 
  • Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy. 
  • Galanin is an estrogen-inducible, secretory product of the rat anterior pituitary. 
  • Gamma-aminobutyric acid inhibits synergistic interleukin-6 release but not transcriptional activation in astrocytoma cells. 
  • Gamma-globin gene promoter elements required for interaction with globin enhancers. 
  • Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis. 
  • Gastrin-releasing peptide (mammalian bombesin) gene expression in health and disease. 
  • Gastrin-releasing peptide gene expression in developing, hyperplastic, and neoplastic human thyroid C-cells. 
  • Gene Expression Profiling in the Hibernating Primate, Cheirogaleus Medius. 
  • Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft. 
  • Gene and protein expression pilot profiling and biomarkers in an experimental mouse model of hypertensive glaucoma. 
  • Gene duplication in Mimulus underlies parallel floral evolution via independent trans-regulatory changes. 
  • Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation. 
  • Gene expression analysis of purified hematopoietic stem cells and committed progenitors. 
  • Gene expression and cell growth are modified by silencing SUMO2 and SUMO3 expression. 
  • Gene expression and larval evolution: changing roles of distal-less and orthodenticle in echinoderm larvae. 
  • Gene expression disruptions of organism versus organ in Drosophila species hybrids. 
  • Gene expression in oogenesis and implications for transgenerational effects of environmental toxicants. 
  • Gene expression in the rectus abdominus muscle of patients with and without pelvic organ prolapse. 
  • Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease. 
  • Gene expression phenotypes of atherosclerosis. 
  • Gene expression phenotypes of oncogenic signaling pathways. 
  • Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma. 
  • Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. 
  • Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. 
  • Gene knockouts of c-src, transforming growth factor beta 1, and tenascin suggest superfluous, nonfunctional expression of proteins. 
  • Gene products promoting remyelination are up-regulated in a cell therapy product manufactured from banked human cord blood. 
  • Gene segment selection in V(D)J recombination: accessibility and beyond. 
  • Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers. 
  • Gene targeting of a CFTR allele in HT29 human epithelial cells. 
  • Gene therapy for glycogen storage diseases. 
  • Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis. 
  • Gene-environment interactions: neurodegeneration in non-mammals and mammals. 
  • Gene-environment regulatory circuits of right ventricular pathology in tetralogy of fallot. 
  • Gene-expression patterns predict phenotypes of immune-mediated thrombosis. 
  • Generation of silent synapses by acute in vivo expression of CaMKIV and CREB. 
  • Genes on the wing. 
  • Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. 
  • Genes with high penetrance for syndromic and non-syndromic autism typically function within the nucleus and regulate gene expression. 
  • Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. 
  • Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. 
  • Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction. 
  • Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies. 
  • Genetic architecture of gene expression traits across diverse populations. 
  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. 
  • Genetic background influences cardiac phenotype in murine chronic kidney disease. 
  • Genetic counseling for fragile x syndrome: updated recommendations of the national society of genetic counselors. 
  • Genetic dissection of rod and cone pathways in the dark-adapted mouse retina. 
  • Genetic dissection of the glutamatergic neuron system in cerebral cortex. 
  • Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases. 
  • Genetic mechanisms that determine oxidative capacity of striated muscles. Control of gene transcription. 
  • Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues. 
  • Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development. 
  • Genetic regulation of pristane-induced oil granuloma responses. 
  • Genetic regulation of rejection and survival following human lung transplantation by the innate immune receptor CD14. 
  • Genetic variation in human NPY expression affects stress response and emotion. 
  • Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa. 
  • Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. 
  • Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. 
  • Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease. 
  • Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways. 
  • Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. 
  • Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. 
  • Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. 
  • Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. 
  • Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. 
  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. 
  • Genome-wide association study of circulating interleukin 6 levels identifies novel loci. 
  • Genome-wide chromatin state transitions associated with developmental and environmental cues. 
  • Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. 
  • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. 
  • Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators. 
  • Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. 
  • Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. 
  • Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells 
  • Genomic features that predict allelic imbalance in humans suggest patterns of constraint on gene expression variation. 
  • Genomics of varicose veins and chronic venous insufficiency. 
  • Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells. 
  • Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis. 
  • Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage. 
  • Global impact of RNA splicing on transcriptome remodeling in the heart. 
  • Global whole-cell FTICR mass spectrometric proteomics analysis of the heat shock response in the radioresistant bacterium Deinococcus radiodurans. 
  • Glucokinase and glucose transporter expression in liver and islets: implications for control of glucose homoeostasis. 
  • Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. 
  • Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. 
  • Glucose-Induced Trophic Shift in an Endosymbiont Dinoflagellate with Physiological and Molecular Consequences. 
  • Glutamate receptor activation regulates mRNA at both transcriptional and posttranscriptional levels. 
  • Glutamine and heat shock protein expression. 
  • Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70. 
  • Glutamine attenuation of cell death and inducible nitric oxide synthase expression following inflammatory cytokine-induced injury is dependent on heat shock factor-1 expression. 
  • Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and Sp1. 
  • Glutamine's protection against cellular injury is dependent on heat shock factor-1. 
  • Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression. 
  • Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression. 
  • Glutamine-mediated dual regulation of heat shock transcription factor-1 activation and expression. 
  • Glutamine: the first clinically relevant pharmacological regulator of heat shock protein expression? 
  • Glycosylation of KEAP1 links nutrient sensing to redox stress signaling. 
  • Gonadotropin regulation of the rat proopiomelanocortin promoter: characterization by transfection of primary ovarian granulosa cells. 
  • Gradients of transgene expression directed by the human myoglobin promoter in the developing mouse heart. 
  • Granulocyte colony-stimulating factor mobilized peripheral blood stem cells enter into G1 of the cell cycle and express higher levels of amphotropic retrovirus receptor mRNA. 
  • Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. 
  • Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells. 
  • Growth and patterning are evolutionarily dissociated in the vestigial wing discs of workers of the red imported fire ant, Solenopsis invicta. 
  • Growth factor modulation of p53-mediated growth arrest versus apoptosis. 
  • Growth hormone and prolactin receptors in adipogenesis: STAT-5 activation, suppressors of cytokine signaling, and regulation of insulin-like growth factor I. 
  • Growth of mesenchymal stem cells on electrospun type I collagen nanofibers. 
  • Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. 
  • Gustatory effects of capsaicin that are independent of TRPV1 receptors. 
  • H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury. 
  • HASF (C3orf58) is a novel ligand of the insulin-like growth factor 1 receptor. 
  • HASF is a stem cell paracrine factor that activates PKC epsilon mediated cytoprotection. 
  • HDMX regulates p53 activity and confers chemoresistance to 3-bis(2-chloroethyl)-1-nitrosourea. 
  • HIF-1α inducing exosomal microRNA-23a expression mediates the cross-talk between tubular epithelial cells and macrophages in tubulointerstitial inflammation. 
  • HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. 
  • HNF-3 beta as a regulator of floor plate development. 
  • Heart regeneration in zebrafish. 
  • Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling. 
  • Hedgehog controls hepatic stellate cell fate by regulating metabolism. 
  • Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis. 
  • Hedgehog signaling patterns mesoderm in the sea urchin. 
  • Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. 
  • Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation. 
  • Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells. 
  • Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression. 
  • Heme oxygenase-1 in lung disease. 
  • Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms. 
  • Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. 
  • Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity. 
  • Hepatic Lipid Catabolism via PPARα-Lysosomal Crosstalk. 
  • Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. 
  • Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. 
  • Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice. 
  • Hepatorenal correction in murine glycogen storage disease type I with a double-stranded adeno-associated virus vector. 
  • Heritable individual-specific and allele-specific chromatin signatures in humans. 
  • Herpes simplex virus proteins ICP27 and UL47 associate with polyadenylate-binding protein and control its subcellular distribution. 
  • HiCAR is a robust and sensitive method to analyze open-chromatin-associated genome organization. 
  • Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork Cells. 
  • Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes. 
  • High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. 
  • High-throughput intracellular biopsy of microRNAs for dissecting the temporal dynamics of cellular heterogeneity. 
  • Highly conserved gene expression profiles in humans with allergic rhinitis altered by immunotherapy. 
  • Highly coordinated gene regulation in mouse skeletal muscle regeneration. 
  • Highly variable penetrance in subjects affected with cavernous cerebral angiomas (CCM) carrying novel CCM1 and CCM2 mutations. 
  • Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism. 
  • Histone modifications at human enhancers reflect global cell-type-specific gene expression. 
  • Homeostasis Despite Instability 
  • Homer: a protein that selectively binds metabotropic glutamate receptors. 
  • Homoeo boxes and strings for the packaging of genes? 
  • Hormonal regulation of a chicken oviduct messenger ribonucleic acid that shares a common domain with gizzard myosin light chain kinase. 
  • Host gene expression classifiers diagnose acute respiratory illness etiology. 
  • Hot Spot Mutagenesis Improves the Functional Expression of Unique Mammalian Odorant Receptors. 
  • Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus-related virus infectivity. 
  • Human Erbb2-induced Erk activity robustly stimulates cycling and functional remodeling of rat and human cardiomyocytes. 
  • Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c. 
  • Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression. 
  • Human S100A15 splice variants are differentially expressed in inflammatory skin diseases and regulated through Th1 cytokines and calcium. 
  • Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine. 
  • Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model. 
  • Human decidual macrophages suppress IFN-γ production by T cells through costimulatory B7-H1:PD-1 signaling in early pregnancy. 
  • Human endometrial epithelial cells cyclically express Toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA. 
  • Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene. 
  • Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response. 
  • Human genome-wide measurement of drug-responsive regulatory activity. 
  • Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. 
  • Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA. 
  • Human proximal tubular cell responses to angiotensin II analyzed using DNA microarray. 
  • Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. 
  • Hybridization studies with a renin cDNA probe: evidence for widespread expression of renin in the mouse. 
  • Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. 
  • Hyperadhesive mutant of type 1-fimbriated Escherichia coli associated with formation of FimH organelles (fimbriosomes). 
  • Hyperglycemia induces insulin resistance on angiotensinogen gene expression in diabetic rat kidney proximal tubular cells. 
  • Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. 
  • Hypoxia in the thymus: role of oxygen tension in thymocyte survival. 
  • Hypoxia promotes proliferation and osteogenic differentiation potentials of human mesenchymal stem cells. 
  • Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning. 
  • Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury. 
  • IAP proteins: blocking the road to death's door. 
  • IFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver. 
  • IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis. 
  • IL-10 stimulatory effects on human NK cells explored by gene profile analysis. 
  • INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice. 
  • IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. 
  • IRGM1 links mitochondrial quality control to autoimmunity. 
  • Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity. 
  • Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1. 
  • Identification and characterization of the human parkin gene promoter. 
  • Identification of Chiari Type I Malformation subtypes using whole genome expression profiles and cranial base morphometrics. 
  • Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[a]pyrene and hydrogen peroxide. 
  • Identification of Long Noncoding RNAs Associated to Human Disease Susceptibility. 
  • Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes. 
  • Identification of a novel set of genes regulated by a unique liver X receptor-alpha -mediated transcription mechanism. 
  • Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction. 
  • Identification of a third autonomous activation domain within the human estrogen receptor. 
  • Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique. 
  • Identification of an amplified, highly expressed gene in a human glioma. 
  • Identification of an essential site for transcriptional activation within the human T-cell receptor delta enhancer. 
  • Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8. 
  • Identification of enhancer regulatory elements that direct epicardial gene expression during zebrafish heart regeneration. 
  • Identification of functional elements and regulatory circuits by Drosophila modENCODE. 
  • Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions. 
  • Identification of negative and positive regulatory elements in the human renin gene. 
  • Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes. 
  • Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis. 
  • Identification of potential regulatory regions in the renin gene. 
  • Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. 
  • Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. 
  • Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity. 
  • Identification, characterization, and evolution of a primate beta-defensin gene cluster. 
  • Identifying gene expression from single cells to single genes. 
  • Idiopathic pancreatitis related to CFTR: complex inheritance and identification of a modifier gene. 
  • Idiotypic determinants used in the analysis of antibody diversification and as regulatory targets. 
  • Idiotypic regulation by isologous monoclonal anti-idiotope antibodies. 
  • Imaging genetics of brain longevity and mental wellness: the next frontier? 
  • Immune profiling: molecular monitoring in renal transplantation. 
  • Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy. 
  • Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes. 
  • Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice. 
  • Immunomodulation of human CD8⁺ T cells by thymoglobulin in vitro. 
  • Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone. 
  • Impact of pronase on flow cytometric crossmatch outcome. 
  • Impact of vaccine type on HIV-1 vaccine elicited antibody durability and B cell gene signature. 
  • Impact on genetic networks in human macrophages by a CCR5 strain of human immunodeficiency virus type 1. 
  • Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. 
  • Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector. 
  • In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation. 
  • In mice with type 2 diabetes, a vascular endothelial growth factor (VEGF)-activating transcription factor modulates VEGF signaling and induces therapeutic angiogenesis after hindlimb ischemia. 
  • In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST. 
  • In vitro studies of acantholysis of keratinocytes induced by pemphigus antibody. 
  • In vitro transcriptional studies of the roles of the thyroid hormone (T3) response elements and minimal promoters in T3-stimulated gene transcription. 
  • In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization. 
  • In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function. 
  • In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. 
  • In-utero epigenetic factors are associated with early-onset myopia in young children. 
  • Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. 
  • Increased E-selectin, IL-8 and IL-10 gene expression in human skin after minimal trauma. 
  • Increased calmodulin affects cell morphology and mRNA levels of cytoskeletal protein genes. 
  • Increased expression of p130 in Alzheimer disease. 
  • Increased expression of the glucose-regulated gene encoding the Mr 78,000 glucose-regulated protein in chemically and radiation-transformed C3H 10T1/2 mouse embryo cells. 
  • Increased expression of utrophin in a slow vs. a fast muscle involves posttranscriptional events. 
  • Increased miR-21-3p in Injured Brain Microvascular Endothelial Cells after Traumatic Brain Injury Aggravates Blood-Brain Barrier Damage by Promoting Cellular Apoptosis and Inflammation through Targeting MAT2B. 
  • Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration. 
  • Increases in ribosomal RNA within the denervated neuropil of the dentate gyrus during reinnervation: evaluation by in situ hybridization using DNA probes complementary to ribosomal RNA. 
  • Increasing amyloid peptide precursor production and its impact on Alzheimer's disease. 
  • Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. 
  • Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus. 
  • Individual and combined effects of shear stress magnitude and spatial gradient on endothelial cell gene expression 
  • Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA3. 
  • Inducible expression of the alpha2-macroglobulin signaling receptor in response to antigenic stimulation: a study of second messenger generation. 
  • Inducible regulation of Runx2-stimulated osteogenesis. 
  • Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires. 
  • Induction of IL-6 expression by mechanical stress in the trabecular meshwork. 
  • Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells. 
  • Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. 
  • Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells. 
  • Induction of c-fos expression in the rostral medulla of rats following electroacupuncture stimulation. 
  • Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep. 
  • Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes. 
  • Induction of lef1 during zebrafish fin regeneration. 
  • Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. 
  • Induction of pro-apoptotic and cell cycle-inhibiting genes in chromium (VI)-treated human lung fibroblasts: lack of effect of ERK. 
  • Induction of tyrosine hydroxylase in the locus coeruleus of transgenic mice in response to stress or nicotine treatment: lack of activation of tyrosine hydroxylase promoter activity. 
  • Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin. 
  • Inefficient dystrophin expression after cord blood transplantation in Duchenne muscular dystrophy. 
  • Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response. 
  • Infection-Induced Vascular Permeability Aids Mycobacterial Growth. 
  • Inflammation and Immune Response in Arrhythmogenic Cardiomyopathy: State-of-the-Art Review. 
  • Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. 
  • Inflammation influences vascular remodeling through AT2 receptor expression and signaling. 
  • Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88. 
  • Inflammatory biomarkers in osteoarthritis. 
  • Inflammatory cytokine gene expression in THP-1 cells exposed to Stachybotrys chartarum and Aspergillus versicolor. 
  • Influence of HLA-C expression level on HIV control. 
  • Influence of androgen on translatable renin mRNA in the mouse submandibular gland. 
  • Influence of network topology and data collection on network inference. 
  • Inhibition by anti-HLA class II monoclonal antibodies of monoclonal antibody OKT3-induced T cell proliferation. Studies at the mRNA level. 
  • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. 
  • Inhibition of Human Adenovirus Replication by the Importin α/β1 Nuclear Import Inhibitor Ivermectin. 
  • Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. 
  • Inhibitory effects of vesicular stomatitis virus on cellular and influenza viral RNA metabolism and protein synthesis. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Injury-induced changes in liver specific transcription factors HNF-1α and HNF-4α. 
  • Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis. 
  • Innate immune mediator profiles and their regulation in a novel polarized immortalized epithelial cell model derived from human endocervix. 
  • Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma. 
  • Inositol diphosphate signaling regulates telomere length. 
  • Inositol phosphate synthesis and the nuclear processes they affect. 
  • Insights from a chimpanzee adipose stromal cell population: opportunities for adult stem cells to expand primate functional genomics. 
  • Insights from molecular signature of in vivo cardiac c-Kit(+) cells following cardiac injury and β-catenin inhibition. 
  • Insights into coral bleaching under heat stress from analysis of gene expression in a sea anemone model system. 
  • Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins. 
  • Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain. 
  • Integration of foreign genes into the mammalian germ line: genetic engineering enters a new era. 
  • Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression. 
  • Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium. 
  • Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. 
  • Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability. 
  • Integrin beta 1 regulates phagosome maturation in macrophages through Rac expression. 
  • Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells. 
  • Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. 
  • Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. 
  • Interaction of plasminogen with dipeptidyl peptidase IV initiates a signal transduction mechanism which regulates expression of matrix metalloproteinase-9 by prostate cancer cells. 
  • Interactions between sustained contractile activity and beta-adrenergic receptors in regulation of gene expression in skeletal muscles. 
  • Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein. 
  • Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation. 
  • Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins. 
  • Interferon regulatory factors are transcriptional regulators of adipogenesis. 
  • Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. 
  • Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway. 
  • Interleukin-1 receptor-associated kinase-1: more evidence. 
  • Interleukin-1-induced nitric oxide production modulates glutathione synthesis in cultured rat hepatocytes. 
  • Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma. 
  • Interleukin-15 increases hepatic regenerative activity. 
  • Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. 
  • Intervening sequence between the leader region and the nucleopcapsid gene of vesicular stomatitis virus RNA. 
  • Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. 
  • Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4. 
  • Intracellular innate immune cascades and interferon defenses that control hepatitis C virus. 
  • Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. 
  • Intracellular mechanisms of gonadotropin-stimulated gene expression in granulosa cells. 
  • Introduction: Regulatory B Cell Special Issue-making all the pieces fit. 
  • Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus. 
  • Invading, Leading and Navigating Cells in Caenorhabditis elegans : Insights into Cell Movement in Vivo . 
  • Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease. 
  • Ion channels under the sun. 
  • Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation. 
  • Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. 
  • Iron increases expression of iron-export protein MTP1 in lung cells. 
  • Iron-dependent regulation of the divalent metal ion transporter. 
  • Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin. 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin. 
  • Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification. 
  • Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. 
  • JNK activation decreases PP2A regulatory subunit B56alpha expression and mRNA stability and increases AUF1 expression in cardiomyocytes. 
  • K+ regulates DNA binding of transcription factors to control gene expression related to neuronal apoptosis. 
  • KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance. 
  • Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials. 
  • Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression. 
  • Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. 
  • Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence. 
  • Kupffer cell depletion by gadolinium chloride enhances liver regeneration after partial hepatectomy in rats. 
  • L-Threonine induces heat shock protein expression and decreases apoptosis in heat-stressed intestinal epithelial cells. 
  • LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. 
  • LMP2 expression and proteasome activity in NOD mice. 
  • LMP2 expression and proteasome activity in NOD mice. 
  • Labor prediction based on the expression patterns of multiple genes related to cervical maturation in human term pregnancy. 
  • Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. 
  • Lactoferrin gene expression is estrogen responsive in human and rhesus monkey endometrium. 
  • Landscape of stimulation-responsive chromatin across diverse human immune cells. 
  • Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. 
  • Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications. 
  • Learning protein-DNA interaction landscapes by integrating experimental data through computational models. 
  • Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor. 
  • Leptin regulates proinflammatory immune responses. 
  • Leptin therapy in insulin-deficient type I diabetes. 
  • Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration. 
  • Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. 
  • Life course socioeconomic status and DNA methylation in genes related to stress reactivity and inflammation: The multi-ethnic study of atherosclerosis. 
  • Life without myoglobin. 
  • Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. 
  • Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene. 
  • Likelihood ratio statistics for gene set enrichment in Alzheimer's disease pathways. 
  • Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element. 
  • Linkage disequilibrium and signatures of positive selection around LINE-1 retrotransposons in the human genome. 
  • Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines. 
  • Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation. 
  • Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression. 
  • Lipopolysaccharide O-antigen promotes persistent murine bacteremia. 
  • Liver X receptor is a regulator of orphan nuclear receptor NOR-1 gene transcription in adipocytes. 
  • Liver X receptors alpha and beta regulate renin expression in vivo. 
  • Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. 
  • LncRNA-MAP3K4 regulates vascular inflammation through the p38 MAPK signaling pathway and cis-modulation of MAP3K4. 
  • Local Dkk1 crosstalk from breeding ornaments impedes regeneration of injured male zebrafish fins. 
  • Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. 
  • Long-distance regulation of fetal V(δ) gene segment TRDV4 by the Tcrd enhancer. 
  • Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. 
  • Longevity and stress in Caenorhabditis elegans. 
  • Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients. 
  • Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination. 
  • Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression. 
  • Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells. 
  • Lubiprostone protects esophageal mucosa from acid injury in porcine esophagus. 
  • Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium. 
  • Lutheran antigens, CD44-related antigens, and Lutheran regulatory genes. 
  • Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. 
  • Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. 
  • Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels. 
  • M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1. 
  • M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice. 
  • MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart. 
  • MCF-7 and T47D human breast cancer cells contain a functional peroxisomal response. 
  • MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. 
  • MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. 
  • MIG-10 (Lamellipodin) stabilizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans. 
  • MKK3 influences mitophagy and is involved in cigarette smoke-induced inflammation. 
  • MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation. 
  • Macrophage immunoregulatory pathways in tuberculosis. 
  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. 
  • Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. 
  • Mapping eQTL by leveraging multiple tissues and DNA methylation. 
  • Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. 
  • Mapping of antibody specificities to VH gene families. 
  • Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip). 
  • Mapping the complexity of transcription control in higher eukaryotes. 
  • Maspin expression profile in human prostate cancer (CaP) and in vitro induction of Maspin expression by androgen ablation. 
  • Mast cell regulation of inflammation and gene expression during antigen-induced bladder inflammation in mice. 
  • Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens. 
  • Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma. 
  • Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26. 
  • MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. 
  • MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5. 
  • Mechanical culture conditions effect gene expression: gravity-induced changes on the space shuttle. 
  • Mechanical load stimulates expression of novel genes in vivo and in vitro in avian flexor tendon cells. 
  • Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. 
  • Mechanism of shortened bones in mucopolysaccharidosis VII. 
  • Mechanisms coordinating ELAV/Hu mRNA regulons. 
  • Mechanisms of MAVS regulation at the mitochondrial membrane. 
  • Mechanisms of cellular protrusions branch out. 
  • Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. 
  • Mechanisms of specificity in neuronal activity-regulated gene transcription. 
  • Mechanisms of the proteinuria induced by Rho GTPases. 
  • Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light. 
  • Mechanotransduction mechanisms for intraventricular diastolic vortex forces and myocardial deformations: part 1. 
  • Members of the myocyte enhancer factor 2 transcription factor family differentially regulate Bdnf transcription in response to neuronal depolarization. 
  • Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors. 
  • Membrane binding of plasmid DNA and endocytic pathways are involved in electrotransfection of mammalian cells. 
  • Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. 
  • Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle. 
  • Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation. 
  • Metabolic regulation of collagen I in fibroblasts isolated from normal peritoneum and adhesions by dichloroacetic acid. 
  • Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype. 
  • Metabolism and vascular fatty acid transport. 
  • Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. 
  • Metaphors and the role of genes in development. 
  • Metazoan operons accelerate recovery from growth-arrested states. 
  • Methylomics of gene expression in human monocytes. 
  • MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex. 
  • Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. 
  • Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. 
  • MicroRNA expression differentiates squamous epithelium from Barrett's esophagus and esophageal cancer. 
  • MicroRNA regulation and interspecific variation of gene expression. 
  • MicroRNA-146a-5p Attenuates Fibrosis-related Molecules in Irradiated and TGF-beta1-Treated Human Hepatic Stellate Cells by Regulating PTPRA-SRC Signaling. 
  • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. 
  • MicroRNAs and Cardiac Regeneration. 
  • MicroRNAs as mediators of viral evasion of the immune system. 
  • MicroRNAs preferentially target the genes with high transcriptional regulation complexity. 
  • MicroRNAs relate to early worsening of renal function in patients with acute heart failure. 
  • Microarray analysis of gene expression in adult retinal ganglion cells. 
  • Microarray analysis of peroxisome proliferator-activated receptor-gamma induced changes in gene expression in macrophages. 
  • Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure. 
  • Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract. 
  • Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha. 
  • Microglia Promote Increased Pain Behavior through Enhanced Inflammation in the Spinal Cord during Repeated Social Defeat Stress. 
  • Microglia and memory: modulation by early-life infection. 
  • Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons. 
  • Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis. 
  • Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome. 
  • Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. 
  • Mitochondrial gene expression in mammalian striated muscle. Evidence that variation in gene dosage is the major regulatory event. 
  • Mitochondrial quality-control dysregulation in conditional HO-1-/- mice. 
  • Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1. 
  • Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression. 
  • Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. 
  • Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs. 
  • Modification of messenger RNA by 2'-O-methylation regulates gene expression in vivo. 
  • Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification. 
  • Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. 
  • Modulation of gene expression in neonatal rat cardiomyocytes by surface modification of polylactide-co-glycolide substrates. 
  • Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP. 
  • Modulation of microfilament protein composition by transfected cytoskeletal actin genes. 
  • Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia. 
  • Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice. 
  • Modulation of tissue repair by regeneration enhancer elements. 
  • Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling. 
  • Modulation of wolframin expression in human placenta during pregnancy: comparison among physiological and pathological states. 
  • Molecular and physiological alterations in murine ventricular dysfunction. 
  • Molecular biology in cardiology: recent developments and opportunities for clinical applications. 
  • Molecular biology of hypertension. 
  • Molecular biology. Enhancers, chromosome position effects, and transgenic mice. 
  • Molecular biology. Versatility of self-cleaving ribozymes. 
  • Molecular cloning and characterization of Aspergillus nidulans cyclophilin B. 
  • Molecular cloning and characterization of a novel histone deacetylase HDAC10. 
  • Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. 
  • Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. 
  • Molecular cloning of KS, a novel rat gene expressed exclusively in the kidney. 
  • Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17beta-estradiol- and nonylphenol-treated fish. 
  • Molecular cloning of the cDNA and promoter sequences for the mouse sodium-hydrogen exchanger regulatory factor. 
  • Molecular evaluation of BK polyomavirus nephropathy. 
  • Molecular genetic mechanisms of allelic specific regulation of murine Comt expression. 
  • Molecular mapping of brain areas involved in parrot vocal communication. 
  • Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells. 
  • Molecular mechanisms of glucose action on angiotensinogen gene expression in rat proximal tubular cells. 
  • Molecular sequelae of topographically guided peripheral nerve repair. 
  • Molecular studies of human renin synthesis and gene expression. 
  • Molecular, cellular, and pharmacological therapies for Duchenne/Becker muscular dystrophies. 
  • Monitoring of receptor dimerization using plasmonic coupling of gold nanoparticles. 
  • Monocyte Polarization is Altered by Total-Body Irradiation in Male Rhesus Macaques: Implications for Delayed Effects of Acute Radiation Exposure. 
  • Morphological and genomic shifts in mole-rat 'queens' increase fecundity but reduce skeletal integrity. 
  • Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice. 
  • Motif module map reveals enforcement of aging by continual NF-kappaB activity. 
  • Motor-driven gene expression. 
  • Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses. 
  • Mouse adenovirus type 1 infection of adipose tissue. 
  • Mouse mammary tumor virus uses mouse but not human transferrin receptor 1 to reach a low pH compartment and infect cells. 
  • Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia. 
  • MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. 
  • Mucosal candidiasis elicits NF-κB activation, proinflammatory gene expression and localized neutrophilia in zebrafish. 
  • Multilayered electrospun scaffolds for tendon tissue engineering. 
  • Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. 
  • Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. 
  • Multiple regulatory events controlling the expression and localization of utrophin in skeletal muscle fibers: insights into a therapeutic strategy for Duchenne muscular dystrophy. 
  • Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand. 
  • Murine V kappa gene expression does not follow the VH paradigm. 
  • Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models. 
  • Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction. 
  • Mutation in collagen II alpha 1 isoforms delineates Stickler and Wagner syndrome phenotypes. 
  • Mutation near the polyoma DNA replication origin permits productive infection of F9 embryonal carcinoma cells. 
  • Mutation of MeCP2 alters transcriptional regulation of select immediate-early genes. 
  • Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch. 
  • Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein. 
  • Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat. 
  • Mutations in SCO2 are associated with autosomal-dominant high-grade myopia. 
  • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. 
  • Mutual information in random Boolean models of regulatory networks. 
  • Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. 
  • Mycobacterium tuberculosis decreases human macrophage IFN-γ responsiveness through miR-132 and miR-26a. 
  • Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. 
  • Myeloperoxidase is increased in human cerebral aneurysms and increases formation and rupture of cerebral aneurysms in mice. 
  • Myoblast proliferation and differentiation on fibronectin-coated self assembled monolayers presenting different surface chemistries. 
  • Myocardial beta-adrenergic receptor signaling in vivo: insights from transgenic mice. 
  • N-myc regulates parkin expression. 
  • N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs. 
  • NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding. 
  • NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment. 
  • NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity. 
  • NF-kappaB factors are essential, but not the switch, for pathogen-related induction of the bovine beta-defensin 5-encoding gene in mammary epithelial cells. 
  • NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma. 
  • NIEHS/EPA Workshops. Growth and differentiation factors. 
  • NIP45 controls the magnitude of the type 2 T helper cell response. 
  • NOTCH-Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine. 
  • Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery. 
  • Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes. 
  • Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes. 
  • Negative regulation of CD4 gene expression by a HES-1-c-Myb complex. 
  • Negative regulation of TSHalpha target gene by thyroid hormone involves histone acetylation and corepressor complex dissociation. 
  • Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration. 
  • Netrin-1 and peripheral nerve regeneration in the adult rat. 
  • Network growth models and genetic regulatory networks. 
  • Neural circuit repair by low-intensity magnetic stimulation requires cellular magnetoreceptors and specific stimulation patterns. 
  • Neuroanatomical circuitry mediating the sensory impact of nicotine in the central nervous system. 
  • Neurobiological functions of transcriptional enhancers. 
  • Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation. 
  • Neuron-specific SUMO knockdown suppresses global gene expression response and worsens functional outcome after transient forebrain ischemia in mice. 
  • Neuronal IL-4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia. 
  • Neuronal activity-regulated gene transcription in synapse development and cognitive function. 
  • Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders. 
  • Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem. 
  • Neuronal pentraxin 1: a novel mediator of hypoxic-ischemic injury in neonatal brain. 
  • Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. 
  • Neurotrophins: transcription and translation. 
  • Neutrophil elastase increases MUC5AC mRNA and protein expression in respiratory epithelial cells. 
  • Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species. 
  • Neutrophil elastase induces mucus cell metaplasia in mouse lung. 
  • Neutrophil elastase inhibition of cell cycle progression in airway epithelial cells in vitro is mediated by p27kip1. 
  • Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. 
  • New insights into E-protein function in lymphocyte development. 
  • New insights into gestational glucose metabolism: lessons learned from 21st century approaches. 
  • New insights into thyroid hormone action. 
  • New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system. 
  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. 
  • New regulators of vertebrate appendage regeneration. 
  • Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. 
  • Night-time neuronal activation of Cluster N in a day- and night-migrating songbird. 
  • Nitric oxide is necessary for CC-class chemokine expression in endotoxin-stimulated ANA-1 murine macrophages. 
  • Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons. 
  • Nitrosation and oxidation in the regulation of gene expression. 
  • Non-redundant roles for interleukin-1 alpha and interleukin-1 beta in regulating human IgG2. 
  • Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene. 
  • Norepinephrine and neuropeptide Y promote proliferation and collagen gene expression of hepatic myofibroblastic stellate cells. 
  • Normal and shear stresses influence the spatial distribution of intracellular adhesion molecule-1 expression in human umbilical vein endothelial cells exposed to sudden expansion flow. 
  • Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest. 
  • Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression. 
  • Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis. 
  • Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis. 
  • Nrf2, a multi-organ protector? 
  • Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. 
  • Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. 
  • Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression. 
  • Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. 
  • Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure 
  • Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains. 
  • Nucleotide sequence and high-level expression of the major Escherichia coli phosphofructokinase. 
  • Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family. 
  • Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences. 
  • Nutrients and the microenvironment to feed a T cell army. 
  • Nutritional regulation of insulin-like growth factor-binding protein gene expression in the ovine fetus and pregnant ewe. 
  • Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. 
  • Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice. 
  • Olfactory receptor gene expression in tiger salamander olfactory epithelium. 
  • Omental gene expression of adiponectin correlates with degree of insulin sensitivity before and after gastric bypass surgery. 
  • One-carbon metabolism and epigenetics: understanding the specificity. 
  • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. 
  • Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function. 
  • Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats. 
  • Oral L-arginine stimulates GLP-1 secretion to improve glucose tolerance in male mice. 
  • Organizing pneumonia in mice and men. 
  • Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene. 
  • Orphan nuclear receptors in T lymphocyte development. 
  • Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels. 
  • Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR. 
  • Osteoclast differentiation and function in aquaglyceroporin AQP9-null mice. 
  • Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages. 
  • Overexpression of hMTH in peripheral lymphocytes and risk of prostate cancer: a case-control analysis. 
  • Overexpression of the arginine-rich carboxy-terminal region of U1 snRNP 70K inhibits both splicing and nucleocytoplasmic transport of mRNA. 
  • Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. 
  • Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice. 
  • Oxidized lipid-mediated alterations in proteoglycan metabolism in cultured pulmonary endothelial cells. 
  • P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells. 
  • P150c-abl is detected in mouse male germ cells by an in vitro kinase assay and is associated with stage-specific phosphoproteins in haploid cells. 
  • P53, cell cycle control and apoptosis: implications for cancer. 
  • PD-L1 is commonly expressed and transcriptionally regulated by STAT3 and MYC in ALK-negative anaplastic large-cell lymphoma. 
  • PER protein interactions and temperature compensation of a circadian clock in Drosophila. 
  • PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI. 
  • PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle. 
  • PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types. 
  • PPAR nuclear receptors and altered RPE lipid metabolism in age-related macular degeneration. 
  • PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans. 
  • PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer. 
  • PTHrP targets HDAC4 and HDAC5 to repress chondrocyte hypertrophy. 
  • Pancreatic digestive enzyme gene expression: effects of CCK and soybean trypsin inhibitor. 
  • Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells. 
  • Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice. 
  • Parkin is not regulated by the unfolded protein response in human neuroblastoma cells. 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. 
  • Pattern of serum protein gene expression in mouse visceral yolk sac and foetal liver. 
  • Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. 
  • Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions. 
  • Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2. 
  • Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease. 
  • Perfluorobutane sulfonate exposure disrupted human placental cytotrophoblast cell proliferation and invasion involving in dysregulating preeclampsia related genes. 
  • Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate. 
  • Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons. 
  • Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia. 
  • Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis. 
  • Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures. 
  • Pervasive Effects of Aging on Gene Expression in Wild Wolves. 
  • Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling. 
  • Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. 
  • Pharmacologic disruption of TRPV1-expressing primary sensory neurons but not genetic deletion of TRPV1 protects mice against pancreatitis. 
  • Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study. 
  • Phosducin regulates transmission at the photoreceptor-to-ON-bipolar cell synapse. 
  • Phosphodiesterase-4 inhibition restored hippocampal long term potentiation after primary blast. 
  • Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking. 
  • Phosphorylation of the rev gene product of human immunodeficiency virus type 1. 
  • Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction. 
  • Photoreceptor synapses degenerate early in experimental choroidal neovascularization. 
  • Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. 
  • Physiological impact of increased expression of the AT1 angiotensin receptor. 
  • Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease. 
  • Pim1 Kinase Overexpression Enhances ckit+ Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine. 
  • Placental expression of lysophosphatidic acid receptors in normal pregnancy and preeclampsia. 
  • Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. 
  • Plasma microRNA-586 is a new biomarker for acute graft-versus-host disease. 
  • Plasmacytoid dendritic cells in inflamed muscle of patients with juvenile dermatomyositis. 
  • Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue. 
  • Polarized monocyte response to cytokine stimulation. 
  • Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals. 
  • Polyteny: still a giant player in chromosome research. 
  • Positive and negative elements regulate human interleukin 3 expression. 
  • Positive selection on MMP3 regulation has shaped heart disease risk. 
  • Positive selection on a human-specific transcription factor binding site regulating IL4 expression. 
  • Post-transcriptional operons and regulons co-ordinating gene expression. 
  • Post-translational modifications regulate the ticking of the circadian clock. 
  • Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy. 
  • Postmortem delay has minimal effect on brain RNA integrity. 
  • Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. 
  • Posttranscriptional generation of macromolecular complexes. 
  • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. 
  • Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection. 
  • Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506. 
  • Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A. 
  • Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids. 
  • Precise regulation of porcupine activity is required for physiological Wnt signaling. 
  • Predicting cell-type-specific gene expression from regions of open chromatin. 
  • Predicting longevity in C. elegans: fertility, mobility and gene expression. 
  • Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). 
  • Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines. 
  • Preface. 
  • Preferential expression of the c-fps protein in chicken macrophages and granulocytic cells. 
  • Pregnancy and Smoothelin-like Protein 1 (SMTNL1) Deletion Promote the Switching of Skeletal Muscle to a Glycolytic Phenotype in Human and Mice. 
  • Prenatal air pollution exposure induces neuroinflammation and predisposes offspring to weight gain in adulthood in a sex-specific manner. 
  • Pretranslational regulation of myoglobin gene expression. 
  • Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. 
  • Principles of microRNA regulation of a human cellular signaling network. 
  • Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines. 
  • Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. 
  • ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine. 
  • Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes. 
  • Proceedings of the fifth international RASopathies symposium: When development and cancer intersect. 
  • Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation. 
  • Programmable mutually exclusive alternative splicing for generating RNA and protein diversity. 
  • Progressive cardiac dysfunction and fibrosis in the cardiomyopathic hamster and effects of growth hormone and angiotensin-converting enzyme inhibition. 
  • Prolactin can modulate CD4+ T-cell response through receptor-mediated alterations in the expression of T-bet. 
  • Prolactin induction of insulin gene expression: the roles of glucose and glucose transporter-2. 
  • Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2. 
  • Prolonged dark adaptation changes connexin expression in the mouse retina. 
  • Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats. 
  • Prospective assessment of midsecretory endometrial leukemia inhibitor factor expression versus ανβ3 testing in women with unexplained infertility. 
  • Prostaglandin-mediated effects in early canine corpus luteum: In vivo effects on vascular and immune factors. 
  • Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin. 
  • Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes. 
  • Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. 
  • Protein Phase Separation Arising from Intrinsic Disorder: First-Principles to Bespoke Applications. 
  • Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism. 
  • Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux. 
  • Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors. 
  • Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl. 
  • Proteomic Profiling of Human Hepatic Stellate Cell Line LX2 Responses to Irradiation and TGF-β1. 
  • Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition. 
  • Pseudomonas syringae pv. tomato DC3000 HopPtoM (CEL ORF3) is important for lesion formation but not growth in tomato and is secreted and translocated by the Hrp type III secretion system in a chaperone-dependent manner. 
  • Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions. 
  • Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. 
  • Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq. 
  • Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response. 
  • Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. 
  • Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes. 
  • Quantitative genetic variation in CD19 expression correlates with autoimmunity. 
  • RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues. 
  • RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts. 
  • REST and stress resistance in ageing and Alzheimer's disease. 
  • RIP3: a molecular switch for necrosis and inflammation. 
  • RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts. 
  • RNA regulons in cancer and inflammation. 
  • RNA regulons: coordination of post-transcriptional events. 
  • RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. 
  • RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells. 
  • RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. 
  • RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro. 
  • RTP family members induce functional expression of mammalian odorant receptors. 
  • RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism. 
  • Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood. 
  • Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. 
  • Rank order metrics for quantifying the association of sequence features with gene regulation. 
  • Rapid decline of GABAA receptor subunit mRNA expression in hippocampus following transient cerebral ischemia in the gerbil. 
  • Rapid dendritic transport of TGN38, a putative cargo receptor. 
  • Ras enhances Myc protein stability. 
  • Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites. 
  • Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5-HT1A receptor via a G protein beta gamma-subunit-initiated pathway. 
  • Rat amylin: cloning and tissue-specific expression in pancreatic islets. 
  • Rat pancreatic kallikrein mRNA: nucleotide sequence and amino acid sequence of the encoded preproenzyme. 
  • Rat thecal/interstitial cells express transforming growth factor-beta type 1 and 2, but only type 2 is regulated by gonadotropin in vitro. 
  • Reactivation of Epstein-Barr Virus by HIF-1α Requires p53. 
  • Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells. 
  • Recent perspectives on the molecular structure and regulation of the beta 2-adrenoceptor. 
  • Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. 
  • Reconciling conflicting models for global control of cell-cycle transcription. 
  • Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. 
  • Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. 
  • Reconstructing regulatory network transitions. 
  • Recovery and expression of messenger RNA from postmortem human brain tissue. 
  • Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation. 
  • Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. 
  • Redox regulation of mitochondrial biogenesis. 
  • Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids. 
  • Regulated expression of a vitellogenin fusion gene in transgenic nematodes. 
  • Regulated expression of heparin-binding EGF-like growth factor (HB-EGF) in the human endometrium: a potential paracrine role during implantation. 
  • Regulated expression of the tyrosine hydroxylase gene by epidermal growth factor. 
  • Regulated heat shock protein 27 expression in human retinal pigment epithelium. 
  • Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling. 
  • Regulating the regulator: NF-kappaB signaling in heart. 
  • Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage. 
  • Regulation of E2A gene expression in B-lymphocyte development. 
  • Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons. 
  • Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2. 
  • Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: the role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-kappaB. 
  • Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. 
  • Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system. 
  • Regulation of PP2Cm expression by miRNA-204/211 and miRNA-22 in mouse and human cells. 
  • Regulation of Sertoli cell differentiation by the testicular paracrine factor PModS: potential role of immediate-early genes. 
  • Regulation of T cell proliferation by JMJD6 and PDGF-BB during chronic hepatitis B infection. 
  • Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters. 
  • Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure. 
  • Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation. 
  • Regulation of Viral Infection by the RNA Modification N6-Methyladenosine. 
  • Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. 
  • Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene. 
  • Regulation of alpha-synuclein expression: implications for Parkinson's disease. 
  • Regulation of alpha1G T-type calcium channel gene (CACNA1G) expression during neuronal differentiation. 
  • Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators. 
  • Regulation of beta-cell glucose transporter gene expression. 
  • Regulation of cell division and of tyrosinase in B16 melanoma cells by imidazole: a possible role for the concept of metabolite gene regulation in mammalian cells. 
  • Regulation of cholecystokinin gene expression in rat intestine. 
  • Regulation of cholecystokinin synthesis and secretion in rat intestine. 
  • Regulation of chondrocytic gene expression by biomechanical signals. 
  • Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: role in mitogenesis and cell proliferation. 
  • Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium. 
  • Regulation of expression of transcobalamin II receptor in the rat. 
  • Regulation of insulin secretion from novel engineered insulinoma cell lines. 
  • Regulation of interleukin-8 expression by cellular pH in human pancreatic adenocarcinoma cells. 
  • Regulation of lipoprotein lipase activity and mRNA in the mammary gland of the lactating mouse. 
  • Regulation of mitochondrial antiviral signaling (MAVS) expression and signaling by the mitochondria-associated endoplasmic reticulum membrane (MAM) protein Gp78. 
  • Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle. 
  • Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. 
  • Regulation of platelet-activating factor synthesis in human neutrophils by MAP kinases. 
  • Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain. 
  • Regulation of ribosomal protein synthesis in an Escherichia coli mutant missing ribosomal protein L1. 
  • Regulation of the Na/H exchanger regulatory factor in OK cells. 
  • Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. 
  • Regulation of the beta 2-adrenergic receptor and its mRNA in the rat ventral prostate by testosterone. 
  • Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone. 
  • Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein. 
  • Regulation of the human interleukin-3 gene. 
  • Regulation of the murine Ddelta2 promoter by upstream stimulatory factor 1, Runx1, and c-Myb. 
  • Regulation of the uncoupling protein-2 gene in INS-1 beta-cells by oleic acid. 
  • Regulation of tissue renin and angiotensin gene expressions. 
  • Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c. 
  • Regulation of utrophin in transgenic mice. 
  • Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. 
  • Regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF-A) expression in podocytes. 
  • Regulation of vitellogenin gene expression in transgenic Caenorhabditis elegans: short sequences required for activation of the vit-2 promoter. 
  • Regulatory B10 cell development and function. 
  • Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. 
  • Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells. 
  • Regulatory elements governing transcription in specialized myofiber subtypes. 
  • Regulatory pathways governing HIV-1 replication. 
  • RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts. 
  • Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding. 
  • Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease. 
  • Relationship between serotonin transporter gene polymorphisms and platelet serotonin transporter sites among African-American cocaine-dependent individuals and healthy volunteers. 
  • Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice. 
  • Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation. 
  • Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression. 
  • Remaining flexible in old alliances: functional plasticity in constrained mutualisms. 
  • Renal systems biology of patients with systemic inflammatory response syndrome. 
  • Renin gene expression, biosynthesis, and cellular pathways of secretion. 
  • Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism. 
  • Repeated swim stress increases pain-induced expression of c-Fos in the rat lumbar cord. 
  • Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. 
  • Repression of interleukin-2 mRNA translation in primary human breast carcinoma tumor-infiltrating lymphocytes. 
  • Reproductive factors in relation to breast cancer characterized by p53 protein expression (United States). 
  • Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins. 
  • Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission. 
  • Requirement for Abl kinases in T cell receptor signaling. 
  • Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells. 
  • Rescuing imperfect antigens for immuno-oncology. 
  • Resistance to apoptosis, increased growth potential, and altered gene expression in cells that survived genotoxic hexavalent chromium [Cr(VI)] exposure. 
  • Response of zonal chondrocytes to extracellular matrix-hydrogels. 
  • Resveratrol Protects Against Hydroquinone-Induced Oxidative Threat in Retinal Pigment Epithelial Cells. 
  • Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity. 
  • Retinoic acid receptors: transcription factors modulating gene regulation, development, and differentiation. 
  • Retinoids and mouse embryonic development. 
  • Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300. 
  • Retroviral vector gene expression in F9 embryonal carcinoma cells. 
  • Reverse engineering gene regulatory networks. 
  • Reversing adipocyte differentiation: implications for treatment of obesity. 
  • Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. 
  • Riboswitches--to kill or save the messenger. 
  • Right ventricular hypertrophy with early dysfunction: A proteomics study in a neonatal model. 
  • Risuteganib Protects against Hydroquinone-induced Injury in Human RPE Cells. 
  • Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: using decoy approach against AP-1 binding site. 
  • Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. 
  • Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. 
  • Role of interleukin-1beta in postoperative cognitive dysfunction. 
  • Role of molecular biology in hypertension research. State of the Art lecture. 
  • Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. 
  • Role of murine intestinal interleukin-1 receptor 1-expressing lymphoid tissue inducer-like cells in Salmonella infection. 
  • Role of natural product diversity in chemical biology. 
  • Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells. 
  • Role of the midbrain dopaminergic system in modulation of vocal brain activation by social context. 
  • Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection. 
  • Rudimentary substrates for vocal learning in a suboscine. 
  • S-nitrosylation in the regulation of gene transcription. 
  • S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4. 
  • SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells. 
  • SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques. 
  • SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model. 
  • SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. 
  • SOCS1, SOCS3, and PIAS1 promote myogenic differentiation by inhibiting the leukemia inhibitory factor-induced JAK1/STAT1/STAT3 pathway. 
  • SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane. 
  • STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression. 
  • STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration. 
  • SV40 enhancer-binding factors are required at the establishment but not the maintenance step of enhancer-dependent transcriptional activation. 
  • Salt restriction leads to activation of adult renal mesenchymal stromal cell-like cells via prostaglandin E2 and E-prostanoid receptor 4. 
  • Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine. 
  • Scleral micro-RNA signatures in adult and fetal eyes. 
  • Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors. 
  • Screening of the Seed Region of MIR184 in Keratoconus Patients from Saudi Arabia. 
  • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 
  • Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. 
  • Searching for transcriptional regulators of Ang II-induced vascular pathology. 
  • Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. 
  • Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway. 
  • Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. 
  • Select de novo gene and protein expression during renal epithelial cell culture in rotating wall vessels is shear stress dependent. 
  • Selection and validation of endogenous reference genes using a high throughput approach. 
  • Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes. 
  • Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB. 
  • Selective expansion of allogeneic regulatory T cells by hepatic stellate cells: role of endotoxin and implications for allograft tolerance. 
  • Semiochemical responsive olfactory sensory neurons are sexually dimorphic and plastic. 
  • Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. 
  • Sensing and integration of Erk and PI3K signals by Myc. 
  • Separate pathways for p53 induction by ionizing radiation and N-(phosphonoacetyl)-L-aspartate. 
  • Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation. 
  • Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression. 
  • Serotonin depletion exacerbates changes in striatal gene expression following quinolinic acid injection. 
  • Serotonin transporter gene moderates the development of emotional problems among children following bullying victimization. 
  • Serotonin- and training-induced dynamic regulation of CREB2 in Aplysia. 
  • Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. 
  • Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats. 
  • Sex Differences in Gene and Protein Expression After Intracerebral Hemorrhage in Mice. 
  • Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. 
  • Signal transduction pathways in hyperoxia-induced lung cell death. 
  • Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes. 
  • Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation. 
  • Simulating natural conditions in the laboratory: a re-examination of sexual isolation between sympatric and allopatric populations of Drosophila pseudoobscura and D. persimilis. 
  • Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen presentation by DCs in patients with relapsing remitting multiple sclerosis. 
  • Single nucleus multi-omics regulatory landscape of the murine pituitary. 
  • Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression. 
  • Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection. 
  • Single-cell genomics identifies cell type-specific molecular changes in autism. 
  • Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α. 
  • Single-walled carbon nanotubes increase pandemic influenza A H1N1 virus infectivity of lung epithelial cells. 
  • Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants. 
  • Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2. 
  • Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis. 
  • Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. 
  • Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta. 
  • Small changes in expression affect predisposition to tumorigenesis. 
  • Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation. 
  • Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo. 
  • Smoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancy. 
  • Social Status and Gene Regulation: Conservation and Context Dependence in Primates. 
  • Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaques. 
  • Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaques. 
  • Social status alters immune regulation and response to infection in macaques. 
  • Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis. 
  • Somatostatin regulates duodenal cholecystokinin and somatostatin messenger RNA. 
  • Some nuts are tougher to crack than others. 
  • Some things I thought I knew about tissue factor that turn out to be wrong. 
  • Sonic hedgehog induces GLT-1 degradation via PKC delta to suppress its transporter activities. 
  • Sox6 as a new modulator of renin expression in the kidney. 
  • Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis. 
  • Spatial preferences of microRNA targets in 3' untranslated regions. 
  • Spatially restricted patterns of expression of the homeobox-containing gene Hox 2.1. during mouse embryogenesis. 
  • Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis. 
  • Specialized motor-driven dusp1 expression in the song systems of multiple lineages of vocal learning birds. 
  • Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction. 
  • Spermatogonial depletion in adult Pin1-deficient mice. 
  • Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology. 
  • Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells. 
  • Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1. 
  • Spontaneous delta- to beta-globin switching in K562 human leukemia cells. 
  • Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation. 
  • Stage-specific expression of B cell translocation gene 1 in rat testis. 
  • Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost. 
  • Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity. 
  • Staphylococcus aureus sepsis induces early renal mitochondrial DNA repair and mitochondrial biogenesis in mice. 
  • Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling. 
  • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. 
  • Stathmin-deficient mice develop an age-dependent axonopathy of the central and peripheral nervous systems. 
  • Stbd1 is highly elevated in skeletal muscle of Pompe disease mice but suppression of its expression does not affect lysosomal glycogen accumulation. 
  • Steroidogenic factor 1: an essential mediator of endocrine development. 
  • Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa. 
  • Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo. 
  • Strengths and limitations of morphological and behavioral analyses in detecting dopaminergic deficiency in Caenorhabditis elegans. 
  • Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53. 
  • Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. 
  • Structural and functional studies of cyclic GMP phosphodiesterase. 
  • Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia. 
  • Structural basis for the differential regulation of DNA by the methionine repressor MetJ. 
  • Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing. 
  • Subcellular localization of the human immunodeficiency virus trans-acting art gene product. 
  • Superimmunity: characterization of a new gene in the immunity region of P1. 
  • Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. 
  • Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. 
  • Suppression of food intake by glucagon-like peptide-1 receptor agonists: relative potencies and role of dipeptidyl peptidase-4. 
  • Suppression of the NF-κB pathway by diesel exhaust particles impairs human antimycobacterial immunity. 
  • Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries. 
  • Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice. 
  • Surface projections of titanium substrates increase antithrombotic endothelial function in response to shear stress. 
  • Surface- and Hydrogel-Mediated Delivery of Nucleic Acid Nanoparticles. 
  • Surfactant protein A modulates induction of regulatory T cells via TGF-β. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis. 
  • Sustained in vivo gene delivery from agarose hydrogel prolongs nonviral gene expression in skin. 
  • Sustained-input switches for transcription factors and microRNAs are central building blocks of eukaryotic gene circuits. 
  • Syncoilin isoform organization and differential expression in murine striated muscle. 
  • Synergism of accessory factors in functional expression of mammalian odorant receptors. 
  • Synergistic effect of shear stress and streptavidin-biotin on the expression of endothelial vasodilator and cytoskeleton genes. 
  • Synergistic enhancement of human bone marrow stromal cell proliferation and osteogenic differentiation on BMP-2-derived and RGD peptide concentration gradients. 
  • Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3. 
  • Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter. 
  • Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition. 
  • Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. 
  • Systemic and Persistent Muscle Gene Expression in Rhesus Monkeys with a Liver De-Targeted Adeno-Associated Virus Vector. 
  • Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors. 
  • Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. 
  • Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer. 
  • Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. 
  • T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms. 
  • T cell development: better living through chromatin. 
  • T lymphocytes from chronic HCV-infected patients are primed for activation-induced apoptosis and express unique pro-apoptotic gene signature. 
  • T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex. 
  • T-bet-dependent expression of osteopontin contributes to T cell polarization. 
  • T-cell-directed cancer vaccines: the melanoma model. 
  • T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair. 
  • T3 or not T3--the slings and arrows of outrageous TR function. 
  • TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. 
  • TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. 
  • TGF-β-Regulated MicroRNAs and Their Function in Cancer Biology. 
  • TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. 
  • TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage. 
  • TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2. 
  • TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. 
  • TNF, IFN-gamma, and endotoxin increase expression of DMT1 in bronchial epithelial cells. 
  • TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors. 
  • TRPC6 expression in neurons is differentially regulated by NR2A- and NR2B-containing NMDA receptors. 
  • TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. 
  • TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. 
  • TSG-6 - a double-edged sword for osteoarthritis (OA). 
  • Targeted activation of c-Jun N-terminal kinase in vivo induces restrictive cardiomyopathy and conduction defects. 
  • Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility. 
  • Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. 
  • Targeted inhibition of V(D)J recombination by a histone methyltransferase. 
  • Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes. 
  • Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro. 
  • Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. 
  • Tau--an inhibitor of deacetylase HDAC6 function. 
  • Temperature-sensitive mRNA degradation is an early event in hepatocyte de-differentiation. 
  • Temporal activation of c-Jun N-terminal kinase in adult transgenic heart via cre-loxP-mediated DNA recombination. 
  • Temporal and tissue-specific expression of distinct retrovirus-like (VL30) elements during mouse development. 
  • Temporal specific patterns of semaphorin gene expression in rat brain after kainic acid-induced status epilepticus. 
  • Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock. 
  • Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion. 
  • Tenascin-C inhibits extracellular matrix-dependent gene expression in mammary epithelial cells. Localization of active regions using recombinant tenascin fragments. 
  • Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation. 
  • The 5'-untranslated region of the N-methyl-D-aspartate receptor NR2A subunit controls efficiency of translation. 
  • The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases. 
  • The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction. 
  • The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells. 
  • The Ca2+-binding protein parvalbumin: molecular cloning and developmental regulation of mRNA abundance. 
  • The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. 
  • The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity. 
  • The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. 
  • The DVR gene family in embryonic development. 
  • The Drosophila Tis11 protein and its effects on mRNA expression in flies. 
  • The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. 
  • The Function of TrophomiRs and Other MicroRNAs in the Human Placenta. 
  • The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. 
  • The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes. 
  • The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity. 
  • The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition. 
  • The Local Edge Machine: inference of dynamic models of gene regulation. 
  • The Lutheran glycoprotein: a multifunctional adhesion receptor. 
  • The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. 
  • The NF-E2 transcription factor. 
  • The Nuclear Pore Complex in Cell Type-Specific Chromatin Structure and Gene Regulation. 
  • The Prader-Willi/Angelman imprinted domain and its control center. 
  • The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. 
  • The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice. 
  • The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia. 
  • The TOR kinases link nutrient sensing to cell growth. 
  • The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality. 
  • The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation. 
  • The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation. 
  • The aryl hydrocarbon nuclear translocator alters CD30-mediated NF-kappaB-dependent transcription. 
  • The balance of benefit and safety of rosiglitazone: important lessons for our system of drug development and postmarketing assessment. 
  • The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease. 
  • The biological significance of substrate inhibition: a mechanism with diverse functions. 
  • The biomarker niche for fibroblast growth factor 23 testing in CKD. 
  • The chemokine CX3CL1 regulates NK cell activity in vivo. 
  • The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. 
  • The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes. 
  • The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression. 
  • The coactivator SRC-1 is an essential coordinator of hepatic glucose production. 
  • The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. 
  • The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure. 
  • The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity. 
  • The dichotomy of p53 regulation by noncoding RNAs. 
  • The dishevelled protein is modified by wingless signaling in Drosophila. 
  • The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. 
  • The dusp1 immediate early gene is regulated by natural stimuli predominantly in sensory input neurons. 
  • The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster. 
  • The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance. 
  • The evolution of transcriptional regulation in eukaryotes. 
  • The evolutionary significance of cis-regulatory mutations. 
  • The expression of viral and cellular genes in papillomas of the choroid plexus induced in transgenic mice. 
  • The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure. 
  • The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. 
  • The g-value paradox. 
  • The genetic regulatory signature of type 2 diabetes in human skeletal muscle. 
  • The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2. 
  • The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. 
  • The helix-loop-helix gene E2A is required for B cell formation. 
  • The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming. 
  • The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. 
  • The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. 
  • The homeodomain protein HOXB13 regulates the cellular response to androgens. 
  • The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution. 
  • The human keratin genes and their differential expression. 
  • The human olfactory transcriptome. 
  • The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes. 
  • The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background. 
  • The indolocarbazole Gö6976 protects neurons from lipopolysaccharide/interferon-gamma-induced cytotoxicity in murine neuron/glia co-cultures. 
  • The influence of maternal body mass index on myometrial oxytocin receptor expression in pregnancy. 
  • The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy. 
  • The iron transporter DMT1. 
  • The mRNA Cap 2'-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes. 
  • The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. 
  • The manganese(III) porphyrin MnTnHex-2-PyP5+ modulates intracellular ROS and breast cancer cell migration: Impact on doxorubicin-treated cells. 
  • The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. 
  • The microtubule interacting drug candidate NAP protects against kainic acid toxicity in a rat model of epilepsy. 
  • The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor. 
  • The myoD gene family: nodal point during specification of the muscle cell lineage. 
  • The nature and significance of differential keratin gene expression. 
  • The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair. 
  • The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus. 
  • The new age of medical genomics. 
  • The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus. 
  • The origin of spicule-forming cells in a 'primitive' sea urchin (Eucidaris tribuloides) which appears to lack primary mesenchyme cells. 
  • The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages. 
  • The oxidative stress response. 
  • The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. 
  • The p53-dependent gamma-ray response of GADD45. 
  • The pallial basal ganglia pathway modulates the behaviorally driven gene expression of the motor pathway. 
  • The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation. 
  • The regulation of granulosa cell proopiomelanocortin messenger ribonucleic acid by androgens and gonadotropins. 
  • The regulation of proenkephalin expression in a distinct population of glial cells. 
  • The relations of major platelet receptor expression during myocardial infarction. Monitoring efficacy of GPIIb/IIIa inhibitors by measuring P-selectin? 
  • The relationship of modulation of major histocompatibility complex class I antigens to retrovirus transformation in rat cell lines. 
  • The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9. 
  • The ribonome: a dominant force in co-ordinating gene expression. 
  • The role of Bcl-xL in mouse RPE cell survival. 
  • The role of Gla proteins in vascular calcification. 
  • The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases. 
  • The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection. 
  • The role of avian retroviral LTRs in the regulation of gene expression and viral replication. 
  • The role of cytokines in posttraumatic arthritis. 
  • The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo. 
  • The role of modulatory calcineurin-interacting proteins in calcineurin signaling. 
  • The role of trophoblastic microRNAs in placental viral infection. 
  • The role of tuberous sclerosis complex 1 in regulating innate immunity. 
  • The roles of structural dynamics in the cellular functions of RNAs. 
  • The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death. 
  • The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease. 
  • The transcription factor HLH-2/E/Daughterless regulates anchor cell invasion across basement membrane in C. elegans. 
  • The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle. 
  • The transcriptional response of the islet to pregnancy in mice. 
  • The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. 
  • The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors. 
  • The upstream enhancer elements of the G6PC promoter are critical for optimal G6PC expression in murine glycogen storage disease type Ia. 
  • The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation. 
  • The utrophin A 5'-untranslated region confers internal ribosome entry site-mediated translational control during regeneration of skeletal muscle fibers. 
  • The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice. 
  • Three periods of regulatory innovation during vertebrate evolution. 
  • Thrombogenesis in atrial fibrillation contributing mechanisms and natural history. 
  • Thymic expression of the transcription factor Nur77 rescues the T cell but not the B cell abnormality of gld/gld mice. 
  • Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. 
  • Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. 
  • Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation. 
  • Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish. 
  • Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. 
  • Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences. 
  • Tissue-specific expression of the mammalian bombesin gene. 
  • Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells. 
  • Topical capsaicin treatment suppresses formalin-induced fos expression in rat spinal cord. 
  • Topographic specificity within membranes of a single muscle detected in vitro. 
  • Topology and control of the cell-cycle-regulated transcriptional circuitry. 
  • Toward computational systems biology. 
  • Toward deciphering the mechanistic role of variations in the Rep1 repeat site in the transcription regulation of SNCA gene. 
  • Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events. 
  • Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism. 
  • Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration. 
  • Trans-kingdom small RNA transfer during host-pathogen interactions: The case of P. falciparum and erythrocytes. 
  • Transcription and processing of human microRNA precursors. 
  • Transcription factor NF-kappaB regulates inducible CD83 gene expression in activated T lymphocytes. 
  • Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans. 
  • Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo. 
  • Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. 
  • Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level. 
  • Transcription interruption may be a common mechanism of c-myc regulation during HL-60 differentiation. 
  • Transcription of class III genes: formation of preinitiation complexes. 
  • Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells. 
  • Transcriptional activation of p21(waf1/cip1) by alkylphospholipids: role of the mitogen-activated protein kinase pathway in the transactivation of the human p21(waf1/cip1) promoter by Sp1. 
  • Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity. 
  • Transcriptional and functional profiles of voltage-gated Na(+) channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain. 
  • Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. 
  • Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. 
  • Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. 
  • Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. 
  • Transcriptional down-regulation of tumor necrosis factor-alpha gene expression by a synthetic peptide homologous to retroviral envelope protein. 
  • Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus. 
  • Transcriptional interference in avian retroviruses--implications for the promoter insertion model of leukaemogenesis. 
  • Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants. 
  • Transcriptional programmes underlying cellular identity and microbial responsiveness in the intestinal epithelium. 
  • Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers. 
  • Transcriptional regulation of changes in growth, cell cycle, and gene expression of Saccharomyces cerevisiae due to changes in buoyancy. 
  • Transcriptional regulation of matrix gla protein. 
  • Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1. 
  • Transcriptional regulation of the human T cell receptor delta gene. 
  • Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region. 
  • Transcriptional regulation of the mouse presenilin-1 gene. 
  • Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP. 
  • Transfection in the third dimension 
  • Transfection of a human cytochrome P-450 gene into the human lymphoblastoid cell line, AHH-1, and use of the recombinant cell line in gene mutation assays. 
  • Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. 
  • Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. 
  • Transforming growth factor-beta1 antisense treatment of rat vein grafts reduces the accumulation of collagen and increases the accumulation of h-caldesmon. 
  • Transforming growth factors beta 1, beta 2, and beta 3 messenger RNA and protein expression in mouse uterus and vagina during estrogen-induced growth: a comparison to other estrogen-regulated genes. 
  • Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans. 
  • Transgenic animals. New approaches to hypertension research. 
  • Transgenic indicator mice for studying activated retinoic acid receptors during development. 
  • Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles. 
  • Transgenic mice for in vivo epigenome editing with CRISPR-based systems. 
  • Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch. 
  • Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism. 
  • Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice. 
  • Transient regulation of c-fos, alpha B-crystallin, and hsp70 in muscle during recovery from contractile activity. 
  • Transposed LEU2 gene of Saccharomyces cerevisiae is regulated normally. 
  • Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers. 
  • Triiodothyronine and dexamethasone alter potassium channel expression and promote electrophysiological maturation of human-induced pluripotent stem cell-derived cardiomyocytes. 
  • Triphenyl phosphate-induced developmental toxicity in zebrafish: potential role of the retinoic acid receptor. 
  • Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli. 
  • Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide. 
  • Tumor necrosis factor alpha gene expression in human peritoneal macrophages is suppressed by extra-abdominal trauma. 
  • Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. 
  • Tumor necrosis factor-alpha induces increased hydrogen peroxide production and Fc receptor expression, but not increased Ia antigen expression by peritoneal macrophages. 
  • Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase. 
  • Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. 
  • Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. 
  • Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. 
  • Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. 
  • UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner. 
  • Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis. 
  • Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3. 
  • Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro. 
  • Unique functional properties of somatostatin-expressing GABAergic neurons in mouse barrel cortex. 
  • Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. 
  • Unmasking a role for sex chromosomes in gene silencing. 
  • Unmodern Synthesis: Developmental Hierarchies and the Origin of Phenotypes. 
  • Unveiling the secrets to her heart. 
  • Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum. 
  • Up-regulated expression of extracellular matrix remodeling genes in phagocytically challenged trabecular meshwork cells. 
  • Up-regulation of SNCA gene expression: implications to synucleinopathies. 
  • Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells. 
  • Upregulation of AKT1 protein expression in forskolin-stimulated macrophage: evidence from ChIP analysis that CREB binds to and activates the AKT1 promoter. 
  • Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis. 
  • Upregulation of molecules associated with T-regulatory function by thymoglobulin pretreatment of human CD4+ cells. 
  • Use of viral systems to study miRNA-mediated regulation of gene expression in human cells. 
  • Using whole mount in situ hybridization to examine thyroid hormone deiodinase expression in embryonic and larval zebrafish: a tool for examining OH-BDE toxicity to early life stages. 
  • VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. 
  • Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. 
  • Variables affecting the T cell receptor V beta repertoire heterogeneity of T cells infiltrating human renal allografts. 
  • Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome. 
  • Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. 
  • Variations in opsin coding sequences cause x-linked cone dysfunction syndrome with myopia and dichromacy. 
  • Vascular control of kidney epithelial transporters. 
  • Versatile biomanufacturing through stimulus-responsive cell-material feedback. 
  • Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's Oncology Group. 
  • Vibratory loading decreases extracellular matrix and matrix metalloproteinase gene expression in rabbit annulus cells. 
  • Viral RNAs: lessons from the enemy. 
  • Viral sequences determining the oncogenicity of avian leukosis viruses. 
  • Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC. 
  • Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus. 
  • Viruses, microRNAs, and host interactions. 
  • Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis. 
  • WT1 and DAX-1 regulate SF-1-mediated human P450arom gene expression in gonadal cells. 
  • What evidence is there for the existence of individual genes with antagonistic pleiotropic effects? 
  • Whole blood gene expression testing for coronary artery disease in nondiabetic patients: major adverse cardiovascular events and interventions in the PREDICT trial. 
  • Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program. 
  • Why do mutations in the ubiquitously expressed housekeeping gene IMPDH1 cause retina-specific photoreceptor degeneration? 
  • Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation. 
  • Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. 
  • X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling. 
  • Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53. 
  • Zebrafish Transcription Factor ORFeome for Gene Discovery and Regulatory Network Elucidation. 
  • [LMP-420, a new therapeutic approach for cerebral malaria?]. 
  • [Proto-oncogene and pain modulation]. 
  • [Using Hsp70 promoter to regulate target gene expression in tumor]. 
  • aFGF, bFGF and NGF differentially regulate neuropeptide expression in dorsal root ganglia after axotomy and induce autotomy. 
  • beta Adrenergic control of c-fos protooncogene expression in developing rat brain regions. 
  • beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase. 
  • beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. 
  • beta-Arrestin: a protein that regulates beta-adrenergic receptor function. 
  • beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. 
  • c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program. 
  • cAMP-Response Element-Binding 3-Like Protein 1 (CREB3L1) is Required for Decidualization and its Expression is Decreased in Women with Endometriosis. 
  • cCXCR1 is a receptor for cIL-8 (9E3/cCAF) and its N- and C-terminal peptides and is also activated by hIL-8 (CXCL8). 
  • cDNA expression arrays: the effects of lactacystin in lipopolysaccharide-induced cystitis. 
  • eNOS, a pressure-dependent regulator of intraocular pressure. 
  • iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome. 
  • mNos2 deletion and human NOS2 replacement in Alzheimer disease models. 
  • miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation. 
  • miR-181a is an intrinsic modulator of T cell sensitivity and selection. 
  • miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. 
  • miR-21-5p: A viable therapeutic strategy for regulating intraocular pressure. 
  • microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. 
  • microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function. 
  • miniMAVS, You Complete Me! 
  • p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. 
  • p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart. 
  • p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. 
  • p38γ activity is required for maintenance of slow skeletal muscle size. 
  • p53 regulates the expression of the tumor suppressor gene maspin. 
  • pH dependence of the Slc4a11-mediated H⁺ conductance is influenced by intracellular lysine residues and modified by disease-linked mutations. 
  • ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress. 
  • α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration. 
  • β-Catenin modulation in neurofibromatosis type 1 bone repair: therapeutic implications. 
  • β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. 
• 

  Keywords of People

  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
  • Ciofani, Maria, Associate Professor of Immunology, Cell Biology
  • Erickson, Harold Paul, Professor Emeritus of Cell Biology, Cell Biology
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hilton, Matthew James, Associate Professor in Orthopaedic Surgery, Cell Biology
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology
  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Immunology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Immunology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Cell Biology
  • McCall, Shannon Jones, Associate Professor of Pathology, Pathology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology
  • Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Olson, Steven Arthur, Goldner Jones Distinguished Professor of Orthopaedic Surgery, Orthopaedic Surgery
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology
  • Shinohara, Mari L., Associate Professor of Immunology, Cell Biology
  • Soderling, Scott Haydn, George Barth Geller Distinguished Professor of Molecular Biology, Cell Biology
  • Sullivan, Beth Ann, Professor of Molecular Genetics and Microbiology, Duke Science & Society
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Swartzwelder, Harry Scott, Professor in Psychiatry and Behavioral Sciences, Duke Science & Society
  • Tsalik, Ephraim, Adjunct Associate Professor in the Department of Medicine, Medicine, Infectious Diseases
  • Tung, Jenny, Associate Professor of Evolutionary Anthropology, Duke Science & Society
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Immunology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yan, Hai, Adjunct Professor of Pathology, Pathology
  • Yildirim, Eda, Assistant Professor of Cell Biology, Cell Biology
  • Zhong, Xiaoping, Professor of Pediatrics, Immunology