Gene Expression Regulation

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  Subject Areas on Research

  • 2'Fluoro Modification Differentially Modulates the Ability of RNAs to Activate Pattern Recognition Receptors. 
  • 5' flanking sequences of the rat tyrosine hydroxylase gene target accurate tissue-specific, developmental, and transsynaptic expression in transgenic mice. 
  • 5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage. 
  • 7, 8-Dihydroxyflavone induces synapse expression of AMPA GluA1 and ameliorates cognitive and spine abnormalities in a mouse model of fragile X syndrome. 
  • 9-cis retinoic acid regulation of rat growth hormone gene expression: potential roles of multiple nuclear hormone receptors. 
  • A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis. 
  • A CRISPR/Cas9-based system for reprogramming cell lineage specification. 
  • A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. 
  • A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation. 
  • A Potential Contributory Role for Ciliary Dysfunction in the 16p11.2 600 kb BP4-BP5 Pathology. 
  • A Progenitor Cell Expressing Transcription Factor RORγt Generates All Human Innate Lymphoid Cell Subsets. 
  • A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. 
  • A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins. 
  • A bistable Rb-E2F switch underlies the restriction point. 
  • A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1. 
  • A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP. 
  • A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. 
  • A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. 
  • A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. 
  • A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. 
  • A centenarian-only approach for assessing gene-gene interaction in human longevity. 
  • A combinatorial mechanism for determining the specificity of E2F activation and repression. 
  • A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon. 
  • A comparative study of the distributions of renin and angiotensinogen messenger ribonucleic acids in rat and mouse tissues. 
  • A compensatory base change in U1 snRNA suppresses a 5' splice site mutation. 
  • A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter. 
  • A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. 
  • A conserved sorting-associated protein is mutant in chorea-acanthocytosis. 
  • A conserved transcriptional enhancer regulates RAG gene expression in developing B cells. 
  • A constitutively active mutant beta 2-adrenergic receptor is constitutively desensitized and phosphorylated. 
  • A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung. 
  • A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression. 
  • A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells. 
  • A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice. 
  • A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity. 
  • A futile metabolic cycle activated in adipocytes by antidiabetic agents. 
  • A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells. 
  • A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4. 
  • A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function. 
  • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. 
  • A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. 
  • A large network of interconnected signaling pathways in human ovarian follicles is supported by the gene expression activity of the granulosa cells. 
  • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. 
  • A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division. 
  • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. 
  • A maximum entropy algorithm for rhythmic analysis of genome-wide expression patterns. 
  • A meta-analysis of gene expression signatures of blood pressure and hypertension. 
  • A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium. 
  • A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes. 
  • A mouse homoeo box gene is expressed during embryogenesis and in adult kidney. 
  • A mouse model of adult-onset anaemia due to erythropoietin deficiency. 
  • A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer. 
  • A naturally occurring gamma globin gene mutation enhances SP1 binding activity. 
  • A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. 
  • A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3. 
  • A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. 
  • A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation. 
  • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. 
  • A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC. 
  • A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. 
  • A novel model for IFN-γ-mediated autoinflammatory syndromes. 
  • A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. 
  • A novel polypeptide secreted by activated human T lymphocytes. 
  • A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling. 
  • A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. 
  • A positive addition to a negative tail's tale. 
  • A potential role for Elf-1 in CD4 promoter function. 
  • A poxvirus-derived vector that directs high levels of expression of cloned genes in mammalian cells. 
  • A rapid and simple procedure for the preparation of homogeneously labeled DNA probes. 
  • A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. 
  • A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy. 
  • A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. 
  • A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest. 
  • A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. 
  • A role for the putative tumor suppressor Bin1 in muscle cell differentiation. 
  • A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged. 
  • A single tube, four-color flow cytometry assay for evaluation of ZAP-70 and CD38 expression in chronic lymphocytic leukemia. 
  • A small-molecule antagonist of the hedgehog signaling pathway. 
  • A statin-dependent QTL for GATM expression is associated with statin-induced myopathy. 
  • A stem structure in fibroblast growth factor receptor 2 transcripts mediates cell-type-specific splicing by approximating intronic control elements. 
  • A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression. 
  • A threshold for central T cell tolerance to an inducible serum protein. 
  • A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells. 
  • A transcription factor affinity-based code for mammalian transcription initiation. 
  • A transcriptional role for C/EBP beta in the neuronal response to axonal injury. 
  • A transforming growth factor beta type I receptor that signals to activate gene expression. 
  • A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis. 
  • A unique role of the DNA fragmentation factor in maintaining genomic stability. 
  • A user's guide to the encyclopedia of DNA elements (ENCODE). 
  • A viral microRNA functions as an orthologue of cellular miR-155. 
  • A whole-genome analysis of premature termination codons. 
  • A yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters. 
  • A20 modulates lipid metabolism and energy production to promote liver regeneration. 
  • A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. 
  • ACE1 regulates expression of the Saccharomyces cerevisiae metallothionein gene. 
  • ACE1 transcription factor produced in Escherichia coli binds multiple regions within yeast metallothionein upstream activation sequences. 
  • ADAM10 is essential for proteolytic activation of Notch during thymocyte development. 
  • ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression. 
  • APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. 
  • APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. 
  • ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry. 
  • ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes. 
  • Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. 
  • Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. 
  • Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages. 
  • Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload. 
  • Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. 
  • Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. 
  • Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease. 
  • Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1. 
  • Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine. 
  • Activating transcription factor 3 induction in sympathetic neurons after axotomy: response to decreased neurotrophin availability. 
  • Activation and repression of mammalian gene expression by the c-myc protein. 
  • Activation of MYD116 (gadd34) expression following transient forebrain ischemia of rat: implications for a role of disturbances of endoplasmic reticulum calcium homeostasis. 
  • Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation. 
  • Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells. 
  • Activation of bovine B cells via surface immunoglobulin M cross-linking or CD40 ligation results in different B-cell phenotypes. 
  • Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy. 
  • Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease. 
  • Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge to MEK1/ERK2 and activate the Elk1 transcription factor. 
  • Activation primes human B lymphocytes to respond to heat shock. 
  • Activation signals regulate heat shock transcription factor 1 in human B lymphocytes. 
  • Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117. 
  • Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice. 
  • Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. 
  • Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons. 
  • Acute brain death alters left ventricular myocardial gene expression. 
  • Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses. 
  • Acute oxygen-sensing mechanisms. 
  • Adaptation of skeletal muscle to increased contractile activity. Expression nuclear genes encoding mitochondrial proteins. 
  • Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. 
  • Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation. 
  • Adenovirus E1A-mediated negative control of genes activated during F9 differentiation. 
  • Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism. 
  • Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease. 
  • Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus. 
  • Advances to Bayesian network inference for generating causal networks from observational biological data. 
  • Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy. 
  • All-trans-retinoic acid mediates G1 arrest but not apoptosis of normal human mammary epithelial cells. 
  • Allele-specific distribution of RNA polymerase II on female X chromosomes. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. 
  • Allelic exclusion of the T cell receptor alpha-chain: developmental regulation of a post-translational event. 
  • Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl. 
  • Allosteric effects of external K+ ions mediated by the aspartate of the GYGD signature sequence in the Kv2.1 K+ channel. 
  • Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch. 
  • Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements. 
  • Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway. 
  • Alteration of Caenorhabditis elegans gene expression by targeted transformation. 
  • Alterations in TNF- and IL-related gene expression in space-flown WI38 human fibroblasts. 
  • Alterations in levels of mRNAs coding for glial fibrillary acidic protein (GFAP) and vimentin genes in the central nervous system of hens treated with diisopropyl phosphorofluoridate (DFP). 
  • Alterations in microRNA expression in stress-induced cellular senescence. 
  • Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. 
  • Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. 
  • Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts. 
  • Altered levels of prothymosin immunoreactive peptide, a growth-related gene product, during liver regeneration after chronic ethanol feeding. 
  • Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. 
  • Altered phenotypic gene expression of 10T1/2 mesenchymal cells in nonuniformly stretched PEGDA hydrogels. 
  • Altered sodium regulation of renal angiotensinogen mRNA in the spontaneously hypertensive rat. 
  • Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. 
  • Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. 
  • Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. 
  • Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. 
  • Ambient but not incremental oxidant generation effects intercellular adhesion molecule 1 induction by tumour necrosis factor alpha in endothelium. 
  • Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev. 
  • Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress. 
  • An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. 
  • An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus. 
  • An analysis of alternatively spliced CD45 mRNA transcripts during T cell maturation in humans. 
  • An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development. 
  • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. 
  • An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia. 
  • An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice. 
  • An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. 
  • An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau. 
  • An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro. 
  • Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation. 
  • Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. 
  • Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration. 
  • Analysis of the individual regulatory components of the IncFII plasmid replication control system. 
  • Ancient and recent positive selection transformed opioid cis-regulation in humans. 
  • Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. 
  • Angiopoietin-1 enhances skeletal muscle regeneration in mice. 
  • Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. 
  • Angiotensin II induces c-fos expression in smooth muscle via transcriptional control. 
  • Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium. 
  • Annotating nonspecific SAGE tags with microarray data. 
  • Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. 
  • Antibodies to stem cell marker antigens reduce engraftment of hematopoietic stem cells. 
  • Antibody formation and mannose-6-phosphate receptor expression impact the efficacy of muscle-specific transgene expression in murine Pompe disease. 
  • Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. 
  • Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. 
  • Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay. 
  • Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection. 
  • Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. 
  • Apolipoprotein E isotype-dependent modulation of microRNA-146a in plasma and brain. 
  • Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury. 
  • Apolipoprotein J/clusterin induction in myocarditis: A localized response gene to myocardial injury. 
  • ApolipoproteinE mimetic peptides improve outcome after focal ischemia. 
  • Apoptosis rate can be accelerated or decelerated by overexpression or reduction of the level of elongation factor-1 alpha. 
  • Applications of a rat multiple tissue gene expression data set. 
  • Applications of targeted gene capture and next-generation sequencing technologies in studies of human deafness and other genetic disabilities. 
  • Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver. 
  • Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement. 
  • Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model. 
  • Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways. 
  • Ascorbic acid modulates collagen type I gene expression by cells from an eye tissue--trabecular meshwork. 
  • Assessment of candidate ocular biomarkers of ageing in a South African adult population: relationship with chronological age and systemic biomarkers. 
  • Assessment of gene expression in peripheral blood using RNAseq before and after weight restoration in anorexia nervosa. 
  • Assessment of the immune capacity of mammary epithelial cells: comparison with mammary tissue after challenge with Escherichia coli. 
  • Association of misexpression with sterility in hybrids of Drosophila simulansand D. mauritiana. 
  • Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function. 
  • Associative learning and stimulus novelty influence the song-induced expression of an immediate early gene in the canary forebrain. 
  • Atherosclerosis and cancer: common molecular pathways of disease development and progression. 
  • Atomic description of the immune complex involved in heparin-induced thrombocytopenia. 
  • Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. 
  • Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. 
  • Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. 
  • B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin. 
  • B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis. 
  • B1 and TRPV-1 receptor genes and their relationship to hyperalgesia following spinal cord injury. 
  • BBS4 regulates the expression and secretion of FSTL1, a protein that participates in ciliogenesis and the differentiation of 3T3-L1. 
  • BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. 
  • BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene. 
  • BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. 
  • Bacterial expression and characterization of proteins derived from the chicken calmodulin cDNA and a calmodulin processed gene. 
  • Bacterial infection remodels the DNA methylation landscape of human dendritic cells. 
  • Balancing acts: molecular control of mammalian iron metabolism. 
  • Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial. 
  • Bayesian analysis of signaling networks governing embryonic stem cell fate decisions. 
  • Bayesian joint analysis of heterogeneous genomics data. 
  • Behaviourally driven gene expression reveals song nuclei in hummingbird brain. 
  • Benchmarking of dynamic Bayesian networks inferred from stochastic time-series data. 
  • Beryllium fluoride-induced cell proliferation: a process requiring P21(ras)-dependent activated signal transduction and NF-kappaB-dependent gene regulation. 
  • Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids. 
  • Beta-arrestin goes nuclear. 
  • Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing. 
  • Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing. 
  • Beta-thalassemia resulting from a single nucleotide substitution in an acceptor splice site. 
  • Beyond intuitive modeling: combining biophysical models with innovative experiments to move the circadian clock field forward. 
  • Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. 
  • Biochemical mechanisms of hormone receptor-effector coupling. Introduction. 
  • Biochemistry. A glucose-to-gene link. 
  • Biological and analytical stability of a peripheral blood gene expression score for obstructive coronary artery disease in the PREDICT and COMPASS studies. 
  • Biological clocks and the coordination theory of RNA operons and regulons. 
  • Biphasic induction of immediate early gene expression accompanies activity-dependent angiogenesis and myofiber remodeling of rabbit skeletal muscle. 
  • Bleomycin induces the hsp 70 heat shock promoter in cultured cells. 
  • Blood pressure homeostasis is maintained by a P311-TGF-β axis. 
  • Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. 
  • Blurring the edges in vertebrate sex determination. 
  • Body size determination in insects: a review and synthesis of size- and brain-dependent and independent mechanisms. 
  • Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. 
  • Bone morphogenetic proteins are expressed by both bone-forming and non-bone-forming lesions. 
  • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. 
  • Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. 
  • Brain gene regulation by territorial singing behavior in freely ranging songbirds. 
  • Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling. 
  • Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo. 
  • Brain-region-specific Molecular Responses to Maternal Separation and Social Defeat Stress in Mice. 
  • CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells. 
  • CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. 
  • CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway. 
  • CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation. 
  • CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression. 
  • CD22: a multifunctional receptor that regulates B lymphocyte survival and signal transduction. 
  • CD25+CD4+ regulatory T cell migration requires L-selectin expression: L-selectin transcriptional regulation balances constitutive receptor turnover. 
  • CD3 delta and epsilon gene expression in CD3-CD16+ natural killer cell clones derived from thymic precursors. 
  • CD40 is a functional activation antigen and B7-independent T cell costimulatory molecule on normal human lung fibroblasts. 
  • CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis. 
  • CD40 mediated activation of gingival and periodontal ligament fibroblasts. 
  • CD44 is a negative regulator of acute pulmonary inflammation and lipopolysaccharide-TLR signaling in mouse macrophages. 
  • CD62-PSGL-1 interactions regulate cytokine chemokine and apoptotic networks in cardiac allograft recipients. 
  • CD8+ T-cell alveolitis in familial pulmonary alveolar microlithiasis. 
  • COMT gene locus: new functional variants. 
  • COPD: balancing oxidants and antioxidants. 
  • CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability. 
  • CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. 
  • CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis. 
  • CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis. 
  • Ca(2+)/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix. 
  • Ca2+/calmodulin-dependent protein kinase IV and calcium signaling. 
  • Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. 
  • Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. 
  • Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology. 
  • Calcineurin signaling and muscle remodeling. 
  • Calcineurin. Structure, function, and inhibition. 
  • Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling. 
  • Calcium regulation of neuronal gene expression. 
  • Calcium, calmodulin and cell proliferation. 
  • Calcium-dependent gene regulation in myocyte hypertrophy and remodeling. 
  • Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology. 
  • Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. 
  • Calmodulin as a regulator of cell growth and gene expression. 
  • Calmodulin is required for cell-cycle progression during G1 and mitosis. 
  • Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. 
  • Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene. 
  • Candidate genes mediating magnetoreception in rainbow trout (Oncorhynchus mykiss). 
  • Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans. 
  • Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice. 
  • Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway. 
  • Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells. 
  • Cartilage tumours and bone development: molecular pathology and possible therapeutic targets. 
  • Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. 
  • Caspase 8 small interfering RNA prevents acute liver failure in mice. 
  • Cathepsin B is up-regulated and mediates extracellular matrix degradation in trabecular meshwork cells following phagocytic challenge. 
  • Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. 
  • Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. 
  • Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. 
  • Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers. 
  • Cell cycle regulation of human pancreatic cancer by tamoxifen. 
  • Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity. 
  • Cell cycle-dependent regulation of smooth muscle cell activation. 
  • Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010. 
  • Cell surface expression of major histocompatibility class I antigens is modulated by P-glycoprotein transporter. 
  • Cell type-specific effects of Notch signaling activation on intervertebral discs: Implications for intervertebral disc degeneration. 
  • Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency. 
  • Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption. 
  • Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells. 
  • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. 
  • Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen. 
  • Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition. 
  • Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblasts. 
  • Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. 
  • Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model. 
  • Changes in sphingomyelinases, ceramide, Bax, Bcl(2), and caspase-3 during and after experimental status epilepticus. 
  • Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging. 
  • Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation. 
  • Characterization of Langerin-expressing dendritic cell subsets in the normal cornea. 
  • Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy. 
  • Characterization of a zinc finger DNA-binding protein expressed specifically in Petunia petals and seedlings. 
  • Characterization of cis-regulatory elements controlling repo transcription in Drosophila melanogaster. 
  • Characterization of equine herpesvirus type 1 immediate early proteins. 
  • Characterization of human Gadd45, a p53-regulated protein. 
  • Characterization of human prorenin expressed in mammalian cells from cloned cDNA. 
  • Characterization of the Saccharomyces cerevisiae high affinity copper transporter Ctr3. 
  • Characterization of the intronic splicing silencers flanking FGFR2 exon IIIb. 
  • Characterization of two labor-induced genes, DSCR1 and TCTE1L, in the pregnant ovine myometrium. 
  • Chemoattractant-induced activation of c-fos gene expression in human monocytes. 
  • Cholinergic receptor subtypes in the olfactory bulbectomy model of depression. 
  • Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix. 
  • Chromatin signatures of the Drosophila replication program. 
  • Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signaling. 
  • Chronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosis. 
  • Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression. 
  • Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion. 
  • Circadian oscillation of gene expression in murine calvarial bone. 
  • Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration. 
  • Clinical expression of Menkes disease in females with normal karyotype. 
  • Cloning and characterization of the rat alpha 1a-adrenergic receptor gene promoter. Demonstration of cell specificity and regulation by hypoxia. 
  • Cloning and developmental expression of the chick type II and type III TGF beta receptors. 
  • Cloning genes that encode drug-metabolizing enzymes: developmental pharmacology and teratology. 
  • Cloning of DNA corresponding to rare transcripts of rat brain: evidence of transcriptional and post-transcriptional control and of the existence of nonpolyadenylated transcripts. 
  • Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13. 
  • Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family. 
  • Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. 
  • Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. 
  • Clozapine-, but not haloperidol-, induced increases in deltaFosB-like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors. 
  • Co-expression of nAChRs and molecules of the bitter taste transduction pathway by epithelial cells of intrapulmonary airways. 
  • Cocaine self-administration in dopamine-transporter knockout mice. 
  • Codon usage regulates human KRAS expression at both transcriptional and translational levels. 
  • Collaborative interactions between MEF-2 and Sp1 in muscle-specific gene regulation. 
  • Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase. 
  • Collagen subtypes III and IV expression in human vein graft atherosclerosis. 
  • Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells. 
  • Combination anti-CD2 and anti-CD3 monoclonal antibodies induce tolerance while altering interleukin-2, interleukin-4, tumor necrosis factor, and transforming growth factor-beta production. 
  • Combination antiretroviral therapy results in a rapid increase in T cell receptor variable region beta repertoire diversity within CD45RA CD8 T cells in human immunodeficiency virus-infected children. 
  • Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. 
  • Combinatorial and synergistic properties of CaMV 35S enhancer subdomains. 
  • Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons. 
  • Combined immunodeficiency due to the selective absence of CD4 inducer T lymphocytes. 
  • Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression. 
  • Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. 
  • Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee. 
  • Comparative analysis of behavioral and transcriptional variation underlying CO2 sensory neuron function and development in Drosophila. 
  • Comparative genomics of mammalian hibernators using gene networks. 
  • Comparison of gene expression profiles induced by coarse, fine, and ultrafine particulate matter. 
  • Compensation and specificity of function within the E2F family. 
  • Competitive displacement of phosphoinositide 3-kinase from beta-adrenergic receptor kinase-1 improves postinfarction adverse myocardial remodeling. 
  • Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses. 
  • Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells. 
  • Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene. 
  • Complex environmental drivers of immunity and resistance in malaria mosquitoes. 
  • Complex regulation of human c-kit transcription by promoter repressors, activators, and specific myb elements. 
  • Complex relationships of nicotinic receptor actions and cognitive functions. 
  • Complex structure and regulation of the ABP/SHBG gene. 
  • Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. 
  • Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. 
  • Comprehensive functional genomic resource and integrative model for the human brain. 
  • Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulation. 
  • Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. 
  • Conditions associated with ER dysfunction activate homer 1a expression. 
  • Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. 
  • Connexin 39.9 protein is necessary for coordinated activation of slow-twitch muscle and normal behavior in zebrafish. 
  • Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation. 
  • Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. 
  • Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations. 
  • Constitutive activation of the aromatic hydrocarbon receptor. 
  • Constitutive expression of placental lactogen in pancreatic beta cells: effects on cell morphology, growth, and gene expression. 
  • Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features. 
  • Consumption of a high-fat diet induces central insulin resistance independent of adiposity. 
  • Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle. 
  • Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys. 
  • Control of electrolyte balance through ubiquitination. 
  • Control of fibroblast senescence and activation of programmed cell death. 
  • Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions. 
  • Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. 
  • Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion. 
  • Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling. 
  • Convergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learners. 
  • Convergent differential regulation of parvalbumin in the brains of vocal learners. 
  • Convergent transcriptional specializations in the brains of humans and song-learning birds. 
  • Cooperation among multiple transcription factors is required for access to minimal T-cell receptor alpha-enhancer chromatin in vivo. 
  • Coordinate reduction of rat pancreatic islet glucokinase and proinsulin mRNA by exercise training. 
  • Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. 
  • Coordinate regulation of mRNAs from multiple calmodulin genes during myoblast differentiation in vitro. 
  • Coordinated activation of corneal wound response genes in vivo as observed by in situ hybridization. 
  • Coordinated posttranscriptional mRNA population dynamics during T-cell activation. 
  • Coordinating expression of RNA binding proteins with their mRNA targets. 
  • Copper-induced binding of cellular factors to yeast metallothionein upstream activation sequences. 
  • Copper: an essential metal in biology. 
  • Copy number variation is associated with gene expression change in archaea. 
  • Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage. 
  • Core and region-enriched networks of behaviorally regulated genes and the singing genome. 
  • Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides. 
  • Correlation of peripheral-blood gene expression with the extent of coronary artery stenosis. 
  • Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. 
  • Coupling fibroblast growth factor 23 production and cleavage: iron deficiency, rickets, and kidney disease. 
  • Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-kappaB activation. 
  • Cowpox virus induces interleukin-10 both in vitro and in vivo. 
  • Cranial irradiation leads to acute and persistent neuroinflammation with delayed increases in T-cell infiltration and CD11c expression in C57BL/6 mouse brain. 
  • Critical role of TNF-α in cerebral aneurysm formation and progression to rupture. 
  • Cross-platform prediction of gene expression signatures. 
  • Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes. 
  • Cutting edge: TGF-beta-induced expression of Foxp3 in T cells is mediated through inactivation of ERK. 
  • Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation. 
  • Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation. 
  • Cytokine regulation of liver injury and repair. 
  • Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells. 
  • Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor. 
  • DIO2 modifies inflammatory responses in chondrocytes. 
  • DNA and RNA topoisomerase activities of Top3β are promoted by mediator protein Tudor domain-containing protein 3. 
  • DNA conformation, topology, and the regulation of c-myc expression. 
  • DNA damage responses: p53 induction, cell cycle perturbations, and apoptosis. 
  • DNA fragments from F9 PyEC mutants increase expression of heterologous genes in transfected F9 cells. 
  • DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes. 
  • DNA repair and epidemiology of basal cell carcinoma. 
  • DNase I sensitivity QTLs are a major determinant of human expression variation. 
  • Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice. 
  • Deciphering the molecular machinery of stem cells: a look at the neoblast gene expression profile. 
  • Decoding the role of regulatory element polymorphisms in complex disease. 
  • Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells. 
  • Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity. 
  • Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. 
  • Defective pericyte recruitment of villous stromal vessels as the possible etiologic cause of hydropic change in complete hydatidiform mole. 
  • Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IV. 
  • Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. 
  • Defining Ca2+/calmodulin-dependent protein kinase cascades in transcriptional regulation. 
  • Defining the human macula transcriptome and candidate retinal disease genes using EyeSAGE. 
  • Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor. 
  • Degree of methylation of transgenes is dependent on gamete of origin. 
  • Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription. 
  • Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. 
  • Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. 
  • Dengue virus-induced autophagy regulates lipid metabolism. 
  • Dependence of corneal stem/progenitor cells on ocular surface innervation. 
  • Depressed expression of adipocyte beta-adrenergic receptors is a common feature of congenital and diet-induced obesity in rodents. 
  • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. 
  • Design and analysis of large-scale biological rhythm studies: a comparison of algorithms for detecting periodic signals in biological data. 
  • Detailed analysis of gene expression during development of T cell lineages in the thymus. 
  • Detection of differentially regulated genes in ischaemic equine intestinal mucosa. 
  • Detection of inducible clindamycin resistance in staphylococci by broth microdilution using erythromycin-clindamycin combination wells. 
  • Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients. 
  • Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials. 
  • Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated. 
  • Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1. 
  • Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance. 
  • Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. 
  • Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel. 
  • Developmental regulation of calmodulin, actin, and tubulin RNAs during rat testis differentiation. 
  • Developmental regulation of mouse SPARC (osteonectin) gene expression. 
  • Developmentally regulated expression of two members of the Nrarp family in zebrafish. 
  • Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice. 
  • Dietary CdSe/ZnS quantum dot exposure in estuarine fish: bioavailability, oxidative stress responses, reproduction, and maternal transfer. 
  • Dietary regulation of glucose-dependent insulinotropic peptide (GIP) gene expression in rat small intestine. 
  • Dietary regulation of rat intestinal cholecystokinin gene expression. 
  • Differences in the anatomic distribution of immediate-early gene expression in amygdala and angular bundle kindling development. 
  • Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia. 
  • Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-Affected Corneas. 
  • Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression. 
  • Differential biomarker gene and protein expressions in nonylphenol and estradiol-17beta treated juvenile rainbow trout (Oncorhynchus mykiss). 
  • Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis? 
  • Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus. 
  • Differential effects of static and dynamic compression on meniscal cell gene expression. 
  • Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. 
  • Differential effects of vitamin d receptor agonists on gene expression in neonatal rat cardiomyocytes. 
  • Differential expression of S1 and elongation factor-1 alpha during rat development. 
  • Differential expression of galectin-1 and its interactions with cells and laminins in the intervertebral disc. 
  • Differential expression of gamma-aminobutyric acidA receptor subunits. 
  • Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. 
  • Differential expression of genes encoding immunomodulatory proteins in response to amphotericin B in human mononuclear cells identified by cDNA microarray analysis. 
  • Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy. 
  • Differential expression of plasminogen activators and their inhibitors in an organotypic skin coculture system. 
  • Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells. 
  • Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock. 
  • Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes. 
  • Differential gene expression and genomic patient stratification following left ventricular assist device support. 
  • Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosis. 
  • Differential gene expression in mouse sclera during ocular development. 
  • Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia. 
  • Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. 
  • Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse. 
  • Differential microRNA regulation of HLA-C expression and its association with HIV control. 
  • Differential modulation of Th1- and Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein. 
  • Differential modulation of gene induction by glucocorticoids and antiglucocorticoids in rat hepatoma tissue culture cells. 
  • Differential molecular mechanism of the estrogen action that regulates lactoferrin gene in human and mouse. 
  • Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens. 
  • Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. 
  • Differential regulation of the dopamine D1, D2 and D3 receptor gene expression and changes in the phenotype of the striatal neurons in mice lacking the dopamine transporter. 
  • Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia. 
  • Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma. 
  • Direct role of Bardet-Biedl syndrome proteins in transcriptional regulation. 
  • Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers. 
  • Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammation. 
  • Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo. 
  • Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells. 
  • Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity. 
  • Disruption of sarcoendoplasmic reticulum calcium ATPase function in Drosophila leads to cardiac dysfunction. 
  • Dissecting high-dimensional phenotypes with bayesian sparse factor analysis of genetic covariance matrices. 
  • Dissection of genetic pathways in C. elegans. 
  • Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. 
  • Distal renal tubules are deficient in aggresome formation and autophagy upon aldosterone administration. 
  • Distinct and histone-specific modifications mediate positive versus negative transcriptional regulation of TSHalpha promoter. 
  • Distinct functions of two isoforms of a homeobox gene, BP1 and DLX7, in the regulation of the beta-globin gene. 
  • Distinct gene expression phenotypes of cells lacking Rb and Rb family members. 
  • Distinct in vivo requirements for establishment versus maintenance of transcriptional repression. 
  • Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator. 
  • Distinct properties of cell-type-specific and shared transcription factor binding sites. 
  • Distinct roles for E2F proteins in cell growth control and apoptosis. 
  • Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. 
  • Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. 
  • Distinctions in the specificity of E2F function revealed by gene expression signatures. 
  • Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest. 
  • Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. 
  • Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells. 
  • Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. 
  • Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation. 
  • Donor-specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population. 
  • Dopamine D1 receptors and phosphorylation of dopamine- and cyclic AMP-regulated phosphoprotein-32 in the medial preoptic area are involved in experience-induced enhancement of male sexual behavior in rats. 
  • Dopamine receptors: from structure to function. 
  • Dopamine: from pharmacology to molecular biology and back. 
  • Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease? 
  • Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation. 
  • Downregulation of RNA polymerase III transcription of the hY3 gene in vitro. 
  • Downregulation of the AU-rich RNA-binding protein ZFP36 in chronic HBV patients: implications for anti-inflammatory therapy. 
  • Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. 
  • Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair. 
  • Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis. 
  • Dynamic DNA methylation across diverse human cell lines and tissues. 
  • Dynamic and redundant regulation of LRRK2 and LRRK1 expression. 
  • Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. 
  • Dysregulated expression of cyclin D1 in normal human mammary epithelial cells inhibits all-trans-retinoic acid-mediated G0/G1-phase arrest and differentiation in vitro. 
  • Dysregulation of WTI (-KTS) is Associated with the Kidney-Specific Effects of the LMX1B R246Q Mutation. 
  • Dysregulation of hedgehog signalling predisposes to synovial chondromatosis. 
  • E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. 
  • E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins. 
  • E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. 
  • E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity. 
  • E2Fs link the control of G1/S and G2/M transcription. 
  • E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activation. 
  • ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. 
  • EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts. 
  • ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. 
  • ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha. 
  • Early differential induction of C-jun in the central nervous system of hens treated with diisopropylphosphorofluoridate (DFP). 
  • Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint. 
  • Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. 
  • Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. 
  • Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. 
  • Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. 
  • Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. 
  • Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. 
  • Editing the Epigenome: Reshaping the Genomic Landscape. 
  • Editing the epigenome: technologies for programmable transcription and epigenetic modulation. 
  • Editorial: studying hormonal regulation by microarrays: distinguishing the trees from the forest. 
  • Effect of Alemtuzumab (CAMPATH 1-H) in patients with inclusion-body myositis. 
  • Effect of CXCL-1/KC production in high risk vascularized corneal allografts on T cell recruitment and graft rejection. 
  • Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes. 
  • Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system. 
  • Effect of cyclic stretch on beta1D-integrin expression and activation of FAK and RhoA. 
  • Effect of ethanol on tumor necrosis factor signaling during liver regeneration. 
  • Effect of furosemide infusion on renal hemodynamics and angiogenesis gene expression in acute renal ischemia/reperfusion. 
  • Effect of herpes simplex virus types 1 and 2 on surface expression of class I major histocompatibility complex antigens on infected cells. 
  • Effect of influenza virus vaccine on the expression of human immunodeficiency virus co-receptor CCR5. 
  • Effect of intracerebroventricular infusion of insulin on glucose-dependent insulinotropic peptide in dogs. 
  • Effect of nucleotide sequences directly downstream from the AUG on the expression of bovine somatotropin in E. coli. 
  • Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors. 
  • Effects of Space Flight on Mouse Liver versus Kidney: Gene Pathway Analyses. 
  • Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors. 
  • Effects of chronic ethanol consumption on cytokine regulation of liver regeneration. 
  • Effects of inhibition of mitochondrial protein synthesis in skeletal muscle. 
  • Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. 
  • Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. 
  • Effects of spaceflight on murine skeletal muscle gene expression. 
  • Effects of tacrolimus (FK506) on human insulin gene expression, insulin mRNA levels, and insulin secretion in HIT-T15 cells. 
  • Efficacy of an adeno-associated virus 8-pseudotyped vector in glycogen storage disease type II. 
  • Efficacy of gene therapy for a prototypical lysosomal storage disease (GSD-II) is critically dependent on vector dose, transgene promoter, and the tissues targeted for vector transduction. 
  • Efficient analysis of stochastic gene dynamics in the non-adiabatic regime using piecewise deterministic Markov processes. 
  • Efficient dendritic cell priming of T lymphocytes depends on the extracellular matrix protein mindin. 
  • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. 
  • Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene. 
  • Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering. 
  • Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers. 
  • Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: soluble L-selectin levels indicate disease severity. 
  • Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration. 
  • Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and CYP1A inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus). 
  • Embryonic germ cells are capable of adipogenic differentiation in vitro and in vivo. 
  • Emerging clinical applications of RNA. 
  • Endogenous avian retroviruses contain deficient promoter and leader sequences. 
  • Endogenous lung stem cells and contribution to disease. 
  • Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. 
  • Endothelial cell diversity revealed by global expression profiling. 
  • Endothelin-1 induces an increase in total protein synthesis and expression of the smooth muscle alpha-actin gene in vascular smooth muscle cells. 
  • Endotoxin and NO induce MIP-1gamma gene transcription in ANA-1 murine macrophages. 
  • Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages. 
  • Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. 
  • Engineering musculoskeletal tissues with human embryonic germ cell derivatives. 
  • Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression. 
  • Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain. 
  • Enhanced central response to dehydration in mice lacking angiotensin AT(1a) receptors. 
  • Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells. 
  • Enhanced vasorelaxation by overexpression of beta 2-adrenergic receptors in large arteries. 
  • Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery. 
  • Enhancement of rAAV2-mediated transgene expression in retina cells in vitro and in vivo by coadministration of low-dose chemotherapeutic drugs. 
  • Enhancer-blocking activity within the DNase I hypersensitive site 2 to 6 region between the TCR alpha and Dad1 genes. 
  • Environmental factors in relation to breast cancer characterized by p53 protein expression. 
  • Eosinophils alter colonic epithelial barrier function: role for major basic protein. 
  • Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders. 
  • Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. 
  • Epigenetic regulation of COL15A1 in smooth muscle cell replicative aging and atherosclerosis. 
  • Epigenetic regulation of gene expression: the effect of altered chromatin structure from yeast to mammals. 
  • Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. 
  • Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions. 
  • Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. 
  • Epithelial-mesenchymal interactions in the alteration of gene expression and morphology following lung injury. 
  • Erythrocyte CR1 expression level does not correlate with a HindIII restriction fragment length polymorphism in Africans; implications for studies on malaria susceptibility. 
  • Erythrocyte invasion profiles are associated with a common invasion ligand polymorphism in Senegalese isolates of Plasmodium falciparum. 
  • Erythroid transcription factor NF-E2 coordinates hemoglobin synthesis. 
  • Erythropoietin mediates terminal granulocytic differentiation of committed myeloid cells with ectopic erythropoietin receptor expression. 
  • Erythropoietin receptor signals both proliferation and erythroid-specific differentiation. 
  • Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats. 
  • Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation. 
  • Estrogen and thyroid hormone interaction on regulation of gene expression. 
  • Estrogen receptor interconversion, factors regulating conformation and functions. 
  • Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity. 
  • Eukaryotic mRNPs may represent posttranscriptional operons. 
  • Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III. 
  • Evaluating functional network inference using simulations of complex biological systems. 
  • Evaluation of CD86/CD28 and CD40/CD154 pathways in regulating monocyte-derived CD80 expression during their interaction with allogeneic endothelium. 
  • Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]. 
  • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. 
  • Evolution of a malaria resistance gene in wild primates. 
  • Evolution. CNCing is believing. 
  • Evolution. Chaperones as buffering agents? 
  • Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 
  • Evolutionary conservation of possible functional domains of the human and murine XIST genes. 
  • Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons. 
  • Exercise training increases electron and substrate shuttling proteins in muscle of overweight men and women with the metabolic syndrome. 
  • Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. 
  • Explicit equilibrium modeling of transcription-factor binding and gene regulation. 
  • Exploiting expression patterns across multiple tissues to map expression quantitative trait loci. 
  • Exposure to azide markedly decreases the abundance of mRNAs encoding cholesterol synthetic enzymes and inhibits cholesterol synthesis. 
  • Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily. 
  • Expression analysis of the matrix GLA protein and VE-cadherin gene promoters in the outflow pathway. 
  • Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel. 
  • Expression and function of Fas on cells damaged by gamma-irradiation in B6 and B6/lpr mice. 
  • Expression and hormonal regulation of coactivator and corepressor genes. 
  • Expression and modulation of RPE cell membrane complement regulatory proteins. 
  • Expression and production of interleukin-10 by human trophoblast: relationship to pregnancy immunotolerance. 
  • Expression and regulation of alpha 1-adrenergic receptors in human tissues. 
  • Expression and sequence analysis of a cDNA encoding the orotidine-5'-monophosphate decarboxylase domain from Ehrlich ascites uridylate synthase. 
  • Expression in aneuploid Drosophila S2 cells. 
  • Expression microarray identifies novel markers of free flap failure in a rat model. 
  • Expression of HSP70 in peripheral lymphocytes of the patients with allergic rhinitis. 
  • Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression. 
  • Expression of RNAs for calmodulin, actins, and tubulins in rat testis cells. 
  • Expression of TGF-beta-related genes during mouse embryo whisker morphogenesis. 
  • Expression of TIMP in fetal and adult mouse tissues studied by in situ hybridization. 
  • Expression of a cloned human interleukin-2 cDNA is enhanced by the substitution of a heterologous mRNA leader region. 
  • Expression of antimicrobial peptides in the normal and involved skin of patients with infective cellulitis. 
  • Expression of differentiation antigens by hybrids of human lymphoblastoid cells. 
  • Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae). 
  • Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture. 
  • Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. 
  • Expression of major histocompatibility complex class I antigens in normal and transformed rat thyroid epithelial cell lines. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of rRNA and tRNA genes in Escherichia coli: evidence for feedback regulation by products of rRNA operons. 
  • Expression of the 71 kDa dystrophin isoform (Dp71) evaluated by gene targeting. 
  • Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. 
  • Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. 
  • Expression of the homeobox gene, Hox 2.1, during mouse embryogenesis. 
  • Expression of the homeobox genes Hox 2.1 and 2.6 during mouse development. 
  • Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog. 
  • Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines. 
  • Expression of the type III TGF-beta receptor is negatively regulated by TGF-beta. 
  • Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells. 
  • Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection. 
  • Expression quantitative trait locus analysis identifies novel genes for statin myopathy. 
  • Extended passaging, but not aldehyde dehydrogenase activity, increases the chondrogenic potential of human adipose-derived adult stem cells. 
  • Extensive changes in the expression of the opioid genes between humans and chimpanzees. 
  • Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection. 
  • Extracellular Calcium Modulates Chondrogenic and Osteogenic Differentiation of Human Adipose-Derived Stem Cells: A Novel Approach for Osteochondral Tissue Engineering Using a Single Stem Cell Source. 
  • FACS analysis of neuronal-glial interactions in the nucleus accumbens following morphine administration. 
  • FKBP12 is not required for the modulation of transforming growth factor beta receptor I signaling activity in embryonic fibroblasts and thymocytes. 
  • FMRP targets distinct mRNA sequence elements to regulate protein expression. 
  • FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans. 
  • FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. 
  • Factors regulating islet regeneration in the post-insulinoma NEDH rat. 
  • Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels. 
  • Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. 
  • Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. 
  • Fatty Acid binding protein 4 is associated with carotid atherosclerosis and outcome in patients with acute ischemic stroke. 
  • Fenoldopam improves corticomedullary oxygen delivery and attenuates angiogenesis gene expression in acute ischemic renal injury. 
  • Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. 
  • Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuli. 
  • Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo. 
  • Fibronectin-integrin signaling is required for L-glutamine's protection against gut injury. 
  • Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse. 
  • Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium. 
  • Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade. 
  • Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder. 
  • Focal expression of mutant huntingtin in the songbird basal ganglia disrupts cortico-basal ganglia networks and vocal sequences. 
  • Focal gene induction in the liver of rats by a heat-inducible promoter using focused ultrasound hyperthermia: preliminary results. 
  • For whom the bird sings: context-dependent gene expression. 
  • Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression. 
  • FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. 
  • Frequency-dependent response of the vascular endothelium to pulsatile shear stress. 
  • Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways. 
  • Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling. 
  • Function and regulation of yeast copperthionein. 
  • Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome. 
  • Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy. 
  • Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. 
  • Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region. 
  • Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function. 
  • Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. 
  • Functional expression of Mammalian odorant receptors. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. 
  • Functional human renin promoter in transfected cells: evidence for cell-specific expression. 
  • Functional overexpression and characterization of human bradykinin subtype 2 receptor in insect cells using the baculovirus system. 
  • Functional properties of a Drosophila homolog of the E2F1 gene. 
  • Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein. 
  • Functional somato-dendritic alpha7-containing nicotinic acetylcholine receptors in the rat basolateral amygdala complex. 
  • Further characterization of erythrocyte p80 and the membrane protein defect of In(Lu) Lu(a-b-) erythrocytes. 
  • G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy. 
  • G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. 
  • G-CSF induces a potentially tolerant gene and immunophenotype profile in T cells in vivo. 
  • G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons. 
  • GAP-43 promoter elements in transgenic zebrafish reveal a difference in signals for axon growth during CNS development and regeneration. 
  • GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts. 
  • GATA4 and the two sides of gene expression reprogramming. 
  • GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats. 
  • GLUTAMINE PREVENTS ACTIVATION OF NF-kappaB AND STRESS KINASE PATHWAYS, ATTENUATES INFLAMMATORY CYTOKINE RELEASE, AND PREVENTS ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FOLLOWING SEPSIS. 
  • Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy. 
  • Galanin is an estrogen-inducible, secretory product of the rat anterior pituitary. 
  • Galectin-3 expression in cardiac remodeling after myocardial infarction. 
  • Gamma-globin gene promoter elements required for interaction with globin enhancers. 
  • Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis. 
  • Gastrin-releasing peptide (mammalian bombesin) gene expression in health and disease. 
  • Gastrin-releasing peptide gene expression in developing, hyperplastic, and neoplastic human thyroid C-cells. 
  • Gene Expression Profiling in the Hibernating Primate, Cheirogaleus Medius. 
  • Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft. 
  • Gene and protein expression pilot profiling and biomarkers in an experimental mouse model of hypertensive glaucoma. 
  • Gene duplication in Mimulus underlies parallel floral evolution via independent trans-regulatory changes. 
  • Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation. 
  • Gene expression and cell growth are modified by silencing SUMO2 and SUMO3 expression. 
  • Gene expression and larval evolution: changing roles of distal-less and orthodenticle in echinoderm larvae. 
  • Gene expression changes and molecular pathways mediating activity-dependent plasticity in visual cortex. 
  • Gene expression clustering using self-organizing maps: analysis of the macrophage response to particulate biomaterials. 
  • Gene expression disruptions of organism versus organ in Drosophila species hybrids. 
  • Gene expression elucidates functional impact of polygenic risk for schizophrenia. 
  • Gene expression in aminergic and peptidergic cells during aggression and defeat: relevance to violence, depression and drug abuse. 
  • Gene expression in oogenesis and implications for transgenerational effects of environmental toxicants. 
  • Gene expression in the rectus abdominus muscle of patients with and without pelvic organ prolapse. 
  • Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease. 
  • Gene expression phenotypes of atherosclerosis. 
  • Gene expression phenotypes of oncogenic signaling pathways. 
  • Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma. 
  • Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure. 
  • Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-alpha and NF-kappab are key components of the innate immune response to the pathogen. 
  • Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. 
  • Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. 
  • Gene knockouts of c-src, transforming growth factor beta 1, and tenascin suggest superfluous, nonfunctional expression of proteins. 
  • Gene products promoting remyelination are up-regulated in a cell therapy product manufactured from banked human cord blood. 
  • Gene segment selection in V(D)J recombination: accessibility and beyond. 
  • Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers. 
  • Gene targeting of a CFTR allele in HT29 human epithelial cells. 
  • Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis. 
  • Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures. 
  • Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications. 
  • Gene-environment interactions: neurodegeneration in non-mammals and mammals. 
  • Gene-expression patterns predict phenotypes of immune-mediated thrombosis. 
  • Generation of silent synapses by acute in vivo expression of CaMKIV and CREB. 
  • Genes associated with pro-apoptotic and protective mechanisms are affected differently on exposure of neuronal cell cultures to arsenite. No indication for endoplasmic reticulum stress despite activation of grp78 and gadd153 expression. 
  • Genes on the wing. 
  • Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. 
  • Genes upregulated in the human trabecular meshwork in response to elevated intraocular pressure. 
  • Genes with high penetrance for syndromic and non-syndromic autism typically function within the nucleus and regulate gene expression. 
  • Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. 
  • Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction. 
  • Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies. 
  • Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. 
  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. 
  • Genetic counseling for fragile x syndrome: updated recommendations of the national society of genetic counselors. 
  • Genetic dissection of rod and cone pathways in the dark-adapted mouse retina. 
  • Genetic enhancement of cognition in a kindred with cone-rod dystrophy due to RIMS1 mutation. 
  • Genetic mechanisms that determine oxidative capacity of striated muscles. Control of gene transcription. 
  • Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues. 
  • Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development. 
  • Genetic regulation of pristane-induced oil granuloma responses. 
  • Genetic regulation of rejection and survival following human lung transplantation by the innate immune receptor CD14. 
  • Genetic variation in human NPY expression affects stress response and emotion. 
  • Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons. 
  • Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa. 
  • Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. 
  • Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. 
  • Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease. 
  • Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. 
  • Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. 
  • Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. 
  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. 
  • Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). 
  • Genome-wide chromatin state transitions associated with developmental and environmental cues. 
  • Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. 
  • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. 
  • Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators. 
  • Genomic and clinical effects associated with a relaxation response mind-body intervention in patients with irritable bowel syndrome and inflammatory bowel disease. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. 
  • Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells. 
  • Genomic features that predict allelic imbalance in humans suggest patterns of constraint on gene expression variation. 
  • Genomics of varicose veins and chronic venous insufficiency. 
  • Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells. 
  • Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis. 
  • Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage. 
  • Global whole-cell FTICR mass spectrometric proteomics analysis of the heat shock response in the radioresistant bacterium Deinococcus radiodurans. 
  • Glucokinase and glucose transporter expression in liver and islets: implications for control of glucose homoeostasis. 
  • Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. 
  • Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. 
  • Glutamate receptor activation regulates mRNA at both transcriptional and posttranscriptional levels. 
  • Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter. 
  • Glutamine and heat shock protein expression. 
  • Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70. 
  • Glutamine attenuation of cell death and inducible nitric oxide synthase expression following inflammatory cytokine-induced injury is dependent on heat shock factor-1 expression. 
  • Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and Sp1. 
  • Glutamine's protection against cellular injury is dependent on heat shock factor-1. 
  • Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression. 
  • Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression. 
  • Glutamine-mediated dual regulation of heat shock transcription factor-1 activation and expression. 
  • Glutamine: the first clinically relevant pharmacological regulator of heat shock protein expression? 
  • Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition. 
  • Glycosylation of KEAP1 links nutrient sensing to redox stress signaling. 
  • Gradients of transgene expression directed by the human myoglobin promoter in the developing mouse heart. 
  • Granulocyte colony-stimulating factor mobilized peripheral blood stem cells enter into G1 of the cell cycle and express higher levels of amphotropic retrovirus receptor mRNA. 
  • Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. 
  • Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells. 
  • Growth and patterning are evolutionarily dissociated in the vestigial wing discs of workers of the red imported fire ant, Solenopsis invicta. 
  • Growth factor modulation of p53-mediated growth arrest versus apoptosis. 
  • Growth hormone and prolactin receptors in adipogenesis: STAT-5 activation, suppressors of cytokine signaling, and regulation of insulin-like growth factor I. 
  • Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. 
  • Gustatory effects of capsaicin that are independent of TRPV1 receptors. 
  • H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury. 
  • HASF (C3orf58) is a novel ligand of the insulin-like growth factor 1 receptor. 
  • HASF is a stem cell paracrine factor that activates PKC epsilon mediated cytoprotection. 
  • HDMX regulates p53 activity and confers chemoresistance to 3-bis(2-chloroethyl)-1-nitrosourea. 
  • HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. 
  • HNF-3 beta as a regulator of floor plate development. 
  • Heart regeneration in zebrafish. 
  • Heat shock and genetic activation of HSF-1 enhance immunity to bacteria. 
  • Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling. 
  • Hedgehog controls hepatic stellate cell fate by regulating metabolism. 
  • Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis. 
  • Hedgehog signaling patterns mesoderm in the sea urchin. 
  • Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. 
  • Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation. 
  • Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells. 
  • Helicobacter pylori CagA activates NF-kappaB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination. 
  • Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression. 
  • Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. 
  • Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity. 
  • Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. 
  • Hepatic β-arrestin 2 is essential for maintaining euglycemia. 
  • Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. 
  • Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice. 
  • Hepatorenal correction in murine glycogen storage disease type I with a double-stranded adeno-associated virus vector. 
  • Heritable individual-specific and allele-specific chromatin signatures in humans. 
  • Herpes simplex virus proteins ICP27 and UL47 associate with polyadenylate-binding protein and control its subcellular distribution. 
  • Heterogeneous gene expression from the inactive X chromosome: an X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others. 
  • Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork Cells. 
  • High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse. 
  • Highly conserved gene expression profiles in humans with allergic rhinitis altered by immunotherapy. 
  • Highly coordinated gene regulation in mouse skeletal muscle regeneration. 
  • Highly variable penetrance in subjects affected with cavernous cerebral angiomas (CCM) carrying novel CCM1 and CCM2 mutations. 
  • Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism. 
  • Histone modifications at human enhancers reflect global cell-type-specific gene expression. 
  • Homeostasis despite instability. 
  • Homer: a protein that selectively binds metabotropic glutamate receptors. 
  • Homocysteine-induced changes in mRNA levels of genes coding for cytoplasmic- and endoplasmic reticulum-resident stress proteins in neuronal cell cultures. 
  • Homoeo boxes and strings for the packaging of genes? 
  • Hormonal regulation of a chicken oviduct messenger ribonucleic acid that shares a common domain with gizzard myosin light chain kinase. 
  • Host gene expression classifiers diagnose acute respiratory illness etiology. 
  • Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus-related virus infectivity. 
  • Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression. 
  • Human S100A15 splice variants are differentially expressed in inflammatory skin diseases and regulated through Th1 cytokines and calcium. 
  • Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine. 
  • Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model. 
  • Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene. 
  • Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response. 
  • Human genome-wide measurement of drug-responsive regulatory activity. 
  • Human lung innate immune response to Bacillus anthracis spore infection. 
  • Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. 
  • Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA. 
  • Human proximal tubular cell responses to angiotensin II analyzed using DNA microarray. 
  • Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44. 
  • Hyaluronan fragments synergize with interferon-gamma to induce the C-X-C chemokines mig and interferon-inducible protein-10 in mouse macrophages. 
  • Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. 
  • Hybridization studies with a renin cDNA probe: evidence for widespread expression of renin in the mouse. 
  • Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. 
  • Hyperadhesive mutant of type 1-fimbriated Escherichia coli associated with formation of FimH organelles (fimbriosomes). 
  • Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. 
  • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. 
  • Hyperphosphorylation of heat shock transcription factor 1 is correlated with transcriptional competence and slow dissociation of active factor trimers. 
  • Hypoxia in the thymus: role of oxygen tension in thymocyte survival. 
  • Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium. 
  • Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. 
  • Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury. 
  • IFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver. 
  • IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance. 
  • IL-10 stimulatory effects on human NK cells explored by gene profile analysis. 
  • IL-18-dependent NKG2D ligand upregulation on accessory cells is mediated by the PI3K/GSK-3 pathway. 
  • IL-1beta decreases the elastic modulus of human tenocytes. 
  • IL-2-controlled expression of multiple T cell trafficking genes and Th2 cytokines in the regulatory T cell-deficient scurfy mice: implication to multiorgan inflammation and control of skin and lung inflammation. 
  • IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection. 
  • IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. 
  • Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity. 
  • Identification and characterization of the human parkin gene promoter. 
  • Identification of Chiari Type I Malformation subtypes using whole genome expression profiles and cranial base morphometrics. 
  • Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[a]pyrene and hydrogen peroxide. 
  • Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes. 
  • Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins. 
  • Identification of a novel repressive element that contributes to neuron-specific gene expression. 
  • Identification of a novel set of genes regulated by a unique liver X receptor-alpha -mediated transcription mechanism. 
  • Identification of a third autonomous activation domain within the human estrogen receptor. 
  • Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique. 
  • Identification of an amplified, highly expressed gene in a human glioma. 
  • Identification of an essential site for transcriptional activation within the human T-cell receptor delta enhancer. 
  • Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8. 
  • Identification of functional elements and regulatory circuits by Drosophila modENCODE. 
  • Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions. 
  • Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. 
  • Identification of negative and positive regulatory elements in the human renin gene. 
  • Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis. 
  • Identification of potential regulatory regions in the renin gene. 
  • Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. 
  • Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. 
  • Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity. 
  • Idiopathic pancreatitis related to CFTR: complex inheritance and identification of a modifier gene. 
  • Idiotypic determinants used in the analysis of antibody diversification and as regulatory targets. 
  • Idiotypic regulation by isologous monoclonal anti-idiotope antibodies. 
  • Imaging genetics of brain longevity and mental wellness: the next frontier? 
  • Imaging neural activity using Thy1-GCaMP transgenic mice. 
  • Immune profiling: molecular monitoring in renal transplantation. 
  • Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy. 
  • Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes. 
  • Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone. 
  • Impact of pronase on flow cytometric crossmatch outcome. 
  • Impact on genetic networks in human macrophages by a CCR5 strain of human immunodeficiency virus type 1. 
  • Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. 
  • Implanted reuptake-deficient or wild-type dopaminergic neurons improve ON L-dopa dyskinesias without OFF-dyskinesias in a rat model of Parkinson's disease. 
  • Implications of hypoxia on mucosal barrier function. 
  • Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector. 
  • In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation. 
  • In mice with type 2 diabetes, a vascular endothelial growth factor (VEGF)-activating transcription factor modulates VEGF signaling and induces therapeutic angiogenesis after hindlimb ischemia. 
  • In utero supplementation with methyl donors enhances allergic airway disease in mice. 
  • In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models. 
  • In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST. 
  • In vitro studies of acantholysis of keratinocytes induced by pemphigus antibody. 
  • In vitro transcriptional studies of the roles of the thyroid hormone (T3) response elements and minimal promoters in T3-stimulated gene transcription. 
  • In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization. 
  • In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function. 
  • In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. 
  • Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. 
  • Increased E-selectin, IL-8 and IL-10 gene expression in human skin after minimal trauma. 
  • Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. 
  • Increased calmodulin affects cell morphology and mRNA levels of cytoskeletal protein genes. 
  • Increased expression of p130 in Alzheimer disease. 
  • Increased expression of the glucose-regulated gene encoding the Mr 78,000 glucose-regulated protein in chemically and radiation-transformed C3H 10T1/2 mouse embryo cells. 
  • Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration. 
  • Increases in ribosomal RNA within the denervated neuropil of the dentate gyrus during reinnervation: evaluation by in situ hybridization using DNA probes complementary to ribosomal RNA. 
  • Increasing amyloid peptide precursor production and its impact on Alzheimer's disease. 
  • Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. 
  • Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus. 
  • Individual and combined effects of shear stress magnitude and spatial gradient on endothelial cell gene expression. 
  • Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA3. 
  • Inducible expression of the alpha2-macroglobulin signaling receptor in response to antigenic stimulation: a study of second messenger generation. 
  • Inducible regulation of Runx2-stimulated osteogenesis. 
  • Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires. 
  • Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages. 
  • Induction of IL-6 expression by mechanical stress in the trabecular meshwork. 
  • Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells. 
  • Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells. 
  • Induction of c-fos expression in the rostral medulla of rats following electroacupuncture stimulation. 
  • Induction of cell stress through gene transfer of an engineered heat shock transcription factor enhances tumor immunogenicity. 
  • Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep. 
  • Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes. 
  • Induction of lef1 during zebrafish fin regeneration. 
  • Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. 
  • Induction of pro-apoptotic and cell cycle-inhibiting genes in chromium (VI)-treated human lung fibroblasts: lack of effect of ERK. 
  • Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis. 
  • Induction of tyrosine hydroxylase in the locus coeruleus of transgenic mice in response to stress or nicotine treatment: lack of activation of tyrosine hydroxylase promoter activity. 
  • Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin. 
  • Inefficient dystrophin expression after cord blood transplantation in Duchenne muscular dystrophy. 
  • Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response. 
  • Infection-Induced Vascular Permeability Aids Mycobacterial Growth. 
  • Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. 
  • Inflammation influences vascular remodeling through AT2 receptor expression and signaling. 
  • Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury. 
  • Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88. 
  • Inflammatory and antioxidant gene expression in C57BL/6J mice after lethal and sublethal ozone exposures. 
  • Inflammatory biomarkers in osteoarthritis. 
  • Inflammatory cytokine gene expression in THP-1 cells exposed to Stachybotrys chartarum and Aspergillus versicolor. 
  • Inflammatory hypoxia: role of hypoxia-inducible factor. 
  • Influence of HLA-C expression level on HIV control. 
  • Influence of androgen on translatable renin mRNA in the mouse submandibular gland. 
  • Influence of network topology and data collection on network inference. 
  • Inhibition by anti-HLA class II monoclonal antibodies of monoclonal antibody OKT3-induced T cell proliferation. Studies at the mRNA level. 
  • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. 
  • Inhibitory effects of vesicular stomatitis virus on cellular and influenza viral RNA metabolism and protein synthesis. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Injury-induced changes in liver specific transcription factors HNF-1α and HNF-4α. 
  • Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. 
  • Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma. 
  • Inositol diphosphate signaling regulates telomere length. 
  • Inositol phosphate synthesis and the nuclear processes they affect. 
  • Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. 
  • Insights from a chimpanzee adipose stromal cell population: opportunities for adult stem cells to expand primate functional genomics. 
  • Insulin-like growth factor binding protein 2 is a growth inhibitory protein conserved in zebrafish. 
  • Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins. 
  • Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain. 
  • Integration of foreign genes into the mammalian germ line: genetic engineering enters a new era. 
  • Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression. 
  • Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. 
  • Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability. 
  • Integrin beta 1 regulates phagosome maturation in macrophages through Rac expression. 
  • Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells. 
  • Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. 
  • Interaction of plasminogen with dipeptidyl peptidase IV initiates a signal transduction mechanism which regulates expression of matrix metalloproteinase-9 by prostate cancer cells. 
  • Interactions between sustained contractile activity and beta-adrenergic receptors in regulation of gene expression in skeletal muscles. 
  • Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein. 
  • Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation. 
  • Interferon regulatory factors are transcriptional regulators of adipogenesis. 
  • Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. 
  • Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway. 
  • Interleukin-1 receptor-associated kinase-1: more evidence. 
  • Interleukin-1-induced nitric oxide production modulates glutathione synthesis in cultured rat hepatocytes. 
  • Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma. 
  • Interleukin-15 increases hepatic regenerative activity. 
  • Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. 
  • Intervening sequence between the leader region and the nucleopcapsid gene of vesicular stomatitis virus RNA. 
  • Intestinal DMT1 is critical for iron absorption in the mouse but is not required for the absorption of copper or manganese. 
  • Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. 
  • Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4. 
  • Intracellular innate immune cascades and interferon defenses that control hepatitis C virus. 
  • Introduction: Regulatory B Cell Special Issue-making all the pieces fit. 
  • Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus. 
  • Invading, Leading and Navigating Cells in Caenorhabditis elegans: Insights into Cell Movement in Vivo. 
  • Ion channels under the sun. 
  • Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation. 
  • Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. 
  • Iron increases expression of iron-export protein MTP1 in lung cells. 
  • Iron-dependent regulation of the divalent metal ion transporter. 
  • Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin. 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin. 
  • Isolation and functional analysis of sporulation-induced transcribed sequences from Saccharomyces cerevisiae. 
  • Isolation of genes negatively or positively co-expressed with human recombination activating gene 1 (RAG1) by differential display PCR (DD RT-PCR). 
  • Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells. 
  • Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification. 
  • Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. 
  • K+ regulates DNA binding of transcription factors to control gene expression related to neuronal apoptosis. 
  • Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials. 
  • Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. 
  • Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence. 
  • Kupffer cell depletion by gadolinium chloride enhances liver regeneration after partial hepatectomy in rats. 
  • L-Threonine induces heat shock protein expression and decreases apoptosis in heat-stressed intestinal epithelial cells. 
  • LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. 
  • LMP2 expression and proteasome activity in NOD mice. 
  • LMP2 expression and proteasome activity in NOD mice. 
  • Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. 
  • Lactoferrin gene expression is estrogen responsive in human and rhesus monkey endometrium. 
  • Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications. 
  • Learning protein-DNA interaction landscapes by integrating experimental data through computational models. 
  • Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes. 
  • Leptin regulates proinflammatory immune responses. 
  • Leptin therapy in insulin-deficient type I diabetes. 
  • Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration. 
  • Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. 
  • Life without myoglobin. 
  • Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. 
  • Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene. 
  • Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element. 
  • Linkage disequilibrium and signatures of positive selection around LINE-1 retrotransposons in the human genome. 
  • Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines. 
  • Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation. 
  • Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression. 
  • Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression. 
  • Liver X receptor is a regulator of orphan nuclear receptor NOR-1 gene transcription in adipocytes. 
  • Liver X receptors alpha and beta regulate renin expression in vivo. 
  • Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. 
  • Local Dkk1 crosstalk from breeding ornaments impedes regeneration of injured male zebrafish fins. 
  • Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. 
  • Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. 
  • Long-distance regulation of fetal V(δ) gene segment TRDV4 by the Tcrd enhancer. 
  • Long-term effect of interferon on keratinocytes that maintain human papillomavirus type 31. 
  • Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. 
  • Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients. 
  • Losartan decreases cardiac muscle fibrosis and improves cardiac function in dystrophin-deficient mdx mice. 
  • Loss of Bardet Biedl syndrome proteins causes defects in peripheral sensory innervation and function. 
  • Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination. 
  • Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression. 
  • Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium. 
  • Lutheran antigens, CD44-related antigens, and Lutheran regulatory genes. 
  • Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. 
  • Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. 
  • M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice. 
  • MAZ elements alter transcription elongation and silencing of the fibroblast growth factor receptor 2 exon IIIb. 
  • MCF-7 and T47D human breast cancer cells contain a functional peroxisomal response. 
  • MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. 
  • MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. 
  • MIG-10 (Lamellipodin) stabilizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans. 
  • MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation. 
  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. 
  • Mammalian metallothionein is functional in yeast. 
  • Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. 
  • Mapping eQTL by leveraging multiple tissues and DNA methylation. 
  • Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. 
  • Mapping of antibody specificities to VH gene families. 
  • Mapping phenotypic landscapes using DNA micro-arrays. 
  • Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip). 
  • Mapping the complexity of transcription control in higher eukaryotes. 
  • Maspin expression profile in human prostate cancer (CaP) and in vitro induction of Maspin expression by androgen ablation. 
  • Mast cell regulation of inflammation and gene expression during antigen-induced bladder inflammation in mice. 
  • Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26. 
  • MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. 
  • MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5. 
  • Mechanical culture conditions effect gene expression: gravity-induced changes on the space shuttle. 
  • Mechanical load stimulates expression of novel genes in vivo and in vitro in avian flexor tendon cells. 
  • Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. 
  • Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. 
  • Mechanism of shortened bones in mucopolysaccharidosis VII. 
  • Mechanisms coordinating ELAV/Hu mRNA regulons. 
  • Mechanisms of cellular protrusions branch out. 
  • Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. 
  • Mechanisms of specificity in neuronal activity-regulated gene transcription. 
  • Mechanisms of the proteinuria induced by Rho GTPases. 
  • Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light. 
  • Mechanistic differences in the activation of estrogen receptor-alpha (ER alpha)- and ER beta-dependent gene expression by cAMP signaling pathway(s). 
  • Members of the myocyte enhancer factor 2 transcription factor family differentially regulate Bdnf transcription in response to neuronal depolarization. 
  • Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors. 
  • Membrane binding of plasmid DNA and endocytic pathways are involved in electrotransfection of mammalian cells. 
  • Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle. 
  • Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation. 
  • Metabolic regulation of collagen I in fibroblasts isolated from normal peritoneum and adhesions by dichloroacetic acid. 
  • Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype. 
  • Metabolism and vascular fatty acid transport. 
  • Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. 
  • Metal-regulated transcription in eukaryotes. 
  • Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes. 
  • Metaphors and the role of genes in development. 
  • Metazoan operons accelerate recovery from growth-arrested states. 
  • Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression. 
  • MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex. 
  • Mice deficient for testis-brain RNA-binding protein exhibit a coordinate loss of TRAX, reduced fertility, altered gene expression in the brain, and behavioral changes. 
  • Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. 
  • Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. 
  • MicroRNA expression differentiates squamous epithelium from Barrett's esophagus and esophageal cancer. 
  • MicroRNA regulation and interspecific variation of gene expression. 
  • MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. 
  • MicroRNA-24 regulates the processing of latent TGFβ1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN. 
  • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. 
  • MicroRNAs and Cardiac Regeneration. 
  • MicroRNAs as mediators of viral evasion of the immune system. 
  • MicroRNAs as new players in the genomic galaxy and disease puzzles. 
  • MicroRNAs preferentially target the genes with high transcriptional regulation complexity. 
  • MicroRNAs relate to early worsening of renal function in patients with acute heart failure. 
  • Microarray analysis of gene expression in adult retinal ganglion cells. 
  • Microarray analysis of peroxisome proliferator-activated receptor-gamma induced changes in gene expression in macrophages. 
  • Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure. 
  • Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract. 
  • Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha. 
  • Microglia and memory: modulation by early-life infection. 
  • Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis. 
  • Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome. 
  • Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics. 
  • Mitochondrial gene expression in mammalian striated muscle. Evidence that variation in gene dosage is the major regulatory event. 
  • Mitochondrial quality-control dysregulation in conditional HO-1-/- mice. 
  • Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1. 
  • Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression. 
  • Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. 
  • Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs. 
  • Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification. 
  • Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. 
  • Modulation of gene expression in neonatal rat cardiomyocytes by surface modification of polylactide-co-glycolide substrates. 
  • Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP. 
  • Modulation of microfilament protein composition by transfected cytoskeletal actin genes. 
  • Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia. 
  • Modulation of tissue repair by regeneration enhancer elements. 
  • Modulation of wolframin expression in human placenta during pregnancy: comparison among physiological and pathological states. 
  • Molecular and biochemical characterization of folate transport proteins in retinal Müller cells. 
  • Molecular and physiological alterations in murine ventricular dysfunction. 
  • Molecular biology in cardiology: recent developments and opportunities for clinical applications. 
  • Molecular biology of hypertension. 
  • Molecular biology. Enhancers, chromosome position effects, and transgenic mice. 
  • Molecular biology. Versatility of self-cleaving ribozymes. 
  • Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro. 
  • Molecular cloning and characterization of Aspergillus nidulans cyclophilin B. 
  • Molecular cloning and characterization of a novel histone deacetylase HDAC10. 
  • Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. 
  • Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. 
  • Molecular cloning of KS, a novel rat gene expressed exclusively in the kidney. 
  • Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17beta-estradiol- and nonylphenol-treated fish. 
  • Molecular cloning of the cDNA and promoter sequences for the mouse sodium-hydrogen exchanger regulatory factor. 
  • Molecular evaluation of BK polyomavirus nephropathy. 
  • Molecular mapping of brain areas involved in parrot vocal communication. 
  • Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells. 
  • Molecular sequelae of topographically guided peripheral nerve repair. 
  • Molecular studies of human renin synthesis and gene expression. 
  • Molt-dependent transcriptomic analysis of cement proteins in the barnacle Amphibalanus amphitrite. 
  • Monitoring of receptor dimerization using plasmonic coupling of gold nanoparticles. 
  • Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice. 
  • Motif module map reveals enforcement of aging by continual NF-kappaB activity. 
  • Motor-driven gene expression. 
  • Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses. 
  • Mouse mammary tumor virus uses mouse but not human transferrin receptor 1 to reach a low pH compartment and infect cells. 
  • Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia. 
  • MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. 
  • Mucosal candidiasis elicits NF-κB activation, proinflammatory gene expression and localized neutrophilia in zebrafish. 
  • Multilayered electrospun scaffolds for tendon tissue engineering. 
  • Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. 
  • Multiple elements may be used for regulation of the GAP-43 gene in different cell-types. 
  • Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. 
  • Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand. 
  • Murine V kappa gene expression does not follow the VH paradigm. 
  • Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models. 
  • Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy. 
  • Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction. 
  • Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons. 
  • Mutation in collagen II alpha 1 isoforms delineates Stickler and Wagner syndrome phenotypes. 
  • Mutation near the polyoma DNA replication origin permits productive infection of F9 embryonal carcinoma cells. 
  • Mutation of MeCP2 alters transcriptional regulation of select immediate-early genes. 
  • Mutation of a putative protein degradation gene LITAF/SIMPLE in Charcot-Marie-Tooth disease 1C. 
  • Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein. 
  • Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat. 
  • Mutations in EMP2 cause childhood-onset nephrotic syndrome. 
  • Mutations in SCO2 are associated with autosomal-dominant high-grade myopia. 
  • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. 
  • Mutual information in random Boolean models of regulatory networks. 
  • Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells. 
  • Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. 
  • Myoblast proliferation and differentiation on fibronectin-coated self assembled monolayers presenting different surface chemistries. 
  • Myocardial beta-adrenergic receptor signaling in vivo: insights from transgenic mice. 
  • N-myc regulates parkin expression. 
  • N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs. 
  • NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment. 
  • NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor. 
  • NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity. 
  • NF-kappaB factors are essential, but not the switch, for pathogen-related induction of the bovine beta-defensin 5-encoding gene in mammary epithelial cells. 
  • NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway. 
  • NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma. 
  • NIEHS/EPA Workshops. Growth and differentiation factors. 
  • NOTCH-Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine. 
  • Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes. 
  • Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes. 
  • Negative regulation of CD4 gene expression by a HES-1-c-Myb complex. 
  • Negative regulation of TSHalpha target gene by thyroid hormone involves histone acetylation and corepressor complex dissociation. 
  • Neisseria gonorrhoeae suppresses dendritic cell-induced, antigen-dependent CD4 T cell proliferation. 
  • Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration. 
  • Netrin-1 and peripheral nerve regeneration in the adult rat. 
  • Network growth models and genetic regulatory networks. 
  • Neural selective activation and temporal regulation of a mammalian GAP-43 promoter in zebrafish. 
  • Neuroanatomical circuitry mediating the sensory impact of nicotine in the central nervous system. 
  • Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation. 
  • Neuron-specific SUMO knockdown suppresses global gene expression response and worsens functional outcome after transient forebrain ischemia in mice. 
  • Neuronal IL-4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia. 
  • Neuronal activity-regulated gene transcription in synapse development and cognitive function. 
  • Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem. 
  • Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology. 
  • Neuronal pentraxin 1: a novel mediator of hypoxic-ischemic injury in neonatal brain. 
  • Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. 
  • Neurotrophins: transcription and translation. 
  • Neutrophil elastase increases MUC5AC mRNA and protein expression in respiratory epithelial cells. 
  • Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species. 
  • Neutrophil elastase induces mucus cell metaplasia in mouse lung. 
  • Neutrophil elastase inhibition of cell cycle progression in airway epithelial cells in vitro is mediated by p27kip1. 
  • Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. 
  • New insights into E-protein function in lymphocyte development. 
  • New insights into gestational glucose metabolism: lessons learned from 21st century approaches. 
  • New insights into thyroid hormone action. 
  • New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system. 
  • New regulators of vertebrate appendage regeneration. 
  • Night-time neuronal activation of Cluster N in a day- and night-migrating songbird. 
  • Nitric oxide is necessary for CC-class chemokine expression in endotoxin-stimulated ANA-1 murine macrophages. 
  • Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons. 
  • Nitrosation and oxidation in the regulation of gene expression. 
  • Non-proteolytic activity of 19S proteasome subunit RPT-6 regulates GATA transcription during response to infection. 
  • Nonlinear protein degradation and the function of genetic circuits. 
  • Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene. 
  • Norepinephrine and neuropeptide Y promote proliferation and collagen gene expression of hepatic myofibroblastic stellate cells. 
  • Normal and shear stresses influence the spatial distribution of intracellular adhesion molecule-1 expression in human umbilical vein endothelial cells exposed to sudden expansion flow. 
  • Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest. 
  • Novel distal eQTL analysis demonstrates effect of population genetic architecture on detecting and interpreting associations. 
  • Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression. 
  • Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis. 
  • Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis. 
  • Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior. 
  • Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis. 
  • Nrf2, a multi-organ protector? 
  • Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. 
  • Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. 
  • Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression. 
  • Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. 
  • Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure. 
  • Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains. 
  • Nucleotide sequence and high-level expression of the major Escherichia coli phosphofructokinase. 
  • Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family. 
  • Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences. 
  • Nutrients and the microenvironment to feed a T cell army. 
  • Nutritional regulation of insulin-like growth factor-binding protein gene expression in the ovine fetus and pregnant ewe. 
  • Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. 
  • Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice. 
  • Olfactory receptor gene expression in tiger salamander olfactory epithelium. 
  • Omental gene expression of adiponectin correlates with degree of insulin sensitivity before and after gastric bypass surgery. 
  • One-carbon metabolism and epigenetics: understanding the specificity. 
  • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. 
  • Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function. 
  • Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats. 
  • Oral L-arginine stimulates GLP-1 secretion to improve glucose tolerance in male mice. 
  • Organizing pneumonia in mice and men. 
  • Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene. 
  • Orphan nuclear receptors in T lymphocyte development. 
  • Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels. 
  • Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR. 
  • Osteoclast differentiation and function in aquaglyceroporin AQP9-null mice. 
  • Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages. 
  • Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo. 
  • Overexpression of hMTH in peripheral lymphocytes and risk of prostate cancer: a case-control analysis. 
  • Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3-L1 adipocytes. 
  • Overexpression of the arginine-rich carboxy-terminal region of U1 snRNP 70K inhibits both splicing and nucleocytoplasmic transport of mRNA. 
  • Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. 
  • Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice. 
  • P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells. 
  • P150c-abl is detected in mouse male germ cells by an in vitro kinase assay and is associated with stage-specific phosphoproteins in haploid cells. 
  • P53, cell cycle control and apoptosis: implications for cancer. 
  • PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI. 
  • PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle. 
  • PPAR nuclear receptors and altered RPE lipid metabolism in age-related macular degeneration. 
  • PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans. 
  • PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. 
  • PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. 
  • PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer. 
  • Pancreatic digestive enzyme gene expression: effects of CCK and soybean trypsin inhibitor. 
  • Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells. 
  • Parameter-specific analgesic effects of electroacupuncture mediated by degree of regulation TRPV1 and P2X3 in inflammatory pain in rats. 
  • Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice. 
  • Parkin is not regulated by the unfolded protein response in human neuroblastoma cells. 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. 
  • Pattern of serum protein gene expression in mouse visceral yolk sac and foetal liver. 
  • Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. 
  • Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions. 
  • Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2. 
  • Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease. 
  • Performance of polymerase chain reaction techniques detecting perforin in the diagnosis of acute renal rejection: a meta-analysis. 
  • Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate. 
  • Peripheral blood signatures of lead exposure. 
  • Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons. 
  • Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia. 
  • Peroxidative stress selectively down-regulates the neuronal stress response activated under conditions of endoplasmic reticulum dysfunction. 
  • Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures. 
  • Pervasive Effects of Aging on Gene Expression in Wild Wolves. 
  • Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling. 
  • Pharmacologic disruption of TRPV1-expressing primary sensory neurons but not genetic deletion of TRPV1 protects mice against pancreatitis. 
  • Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study. 
  • Phosducin regulates transmission at the photoreceptor-to-ON-bipolar cell synapse. 
  • Phosphodiesterase-4 inhibition restored hippocampal long term potentiation after primary blast. 
  • Phosphorylation of the rev gene product of human immunodeficiency virus type 1. 
  • Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction. 
  • Photoreceptor synapses degenerate early in experimental choroidal neovascularization. 
  • Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. 
  • Physiological impact of increased expression of the AT1 angiotensin receptor. 
  • Physiological regulation of uteroglobin/CCSP expression. 
  • Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease. 
  • Pickpocket is a DEG/ENaC protein required for mechanical nociception in Drosophila larvae. 
  • Pim1 Kinase Overexpression Enhances ckit+ Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine. 
  • Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight. 
  • Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. 
  • Plasma microRNA-586 is a new biomarker for acute graft-versus-host disease. 
  • Plasmacytoid dendritic cells in inflamed muscle of patients with juvenile dermatomyositis. 
  • Plasmodium vivax Infections over 3 Years in Duffy Blood Group Negative Malians in Bandiagara, Mali. 
  • Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue. 
  • Polarized monocyte response to cytokine stimulation. 
  • Poly(alpha-hydroxy acids): carriers for bone morphogenetic proteins. 
  • Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals. 
  • Polyteny: still a giant player in chromosome research. 
  • Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis. 
  • Positive and negative elements regulate human interleukin 3 expression. 
  • Positive selection on MMP3 regulation has shaped heart disease risk. 
  • Positive selection on a human-specific transcription factor binding site regulating IL4 expression. 
  • Post-transcriptional operons and regulons co-ordinating gene expression. 
  • Post-translational modifications regulate the ticking of the circadian clock. 
  • Post-translational regulation enables robust p53 regulation. 
  • Postmortem delay has minimal effect on brain RNA integrity. 
  • Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. 
  • Posttranscriptional generation of macromolecular complexes. 
  • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. 
  • Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506. 
  • Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A. 
  • Precise regulation of porcupine activity is required for physiological Wnt signaling. 
  • Predicted effect of circadian clock modulation of NHE3 of a proximal tubule cell on sodium transport. 
  • Predicting cell-type-specific gene expression from regions of open chromatin. 
  • Predicting longevity in C. elegans: fertility, mobility and gene expression. 
  • Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). 
  • Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines. 
  • Preferential expression of the c-fps protein in chicken macrophages and granulocytic cells. 
  • Pregnancy and Smoothelin-like Protein 1 (SMTNL1) Deletion Promote the Switching of Skeletal Muscle to a Glycolytic Phenotype in Human and Mice. 
  • Prenatal air pollution exposure induces neuroinflammation and predisposes offspring to weight gain in adulthood in a sex-specific manner. 
  • Pretranslational regulation of myoglobin gene expression. 
  • Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. 
  • Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. 
  • Principles of microRNA regulation of a human cellular signaling network. 
  • Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines. 
  • Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. 
  • ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine. 
  • Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes. 
  • Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation. 
  • Progressive cardiac dysfunction and fibrosis in the cardiomyopathic hamster and effects of growth hormone and angiotensin-converting enzyme inhibition. 
  • Prolactin induction of insulin gene expression: the roles of glucose and glucose transporter-2. 
  • Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2. 
  • Prolonged dark adaptation changes connexin expression in the mouse retina. 
  • Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats. 
  • Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin. 
  • Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes. 
  • Proteasome inhibitor induced gene expression profiles reveal overexpression of transcriptional regulators ATF3, GADD153 and MAD1. 
  • Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. 
  • Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux. 
  • Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl. 
  • Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition. 
  • Proteomics of Fuchs' endothelial corneal dystrophy support that the extracellular matrix of Descemet's membrane is disordered. 
  • Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions. 
  • Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. 
  • Purkinje cell protein-2 regulatory regions and transgene expression in cerebellar compartments. 
  • Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq. 
  • Quantifying negative feedback regulation by micro-RNAs. 
  • Quantitative analysis of gene function in the Drosophila embryo. 
  • Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes. 
  • Quantitative genetic variation in CD19 expression correlates with autoimmunity. 
  • RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues. 
  • RIP3: a molecular switch for necrosis and inflammation. 
  • RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts. 
  • RNA regulons in cancer and inflammation. 
  • RNA regulons: coordination of post-transcriptional events. 
  • RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. 
  • RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells. 
  • RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. 
  • RTP family members induce functional expression of mammalian odorant receptors. 
  • RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism. 
  • Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood. 
  • Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. 
  • Rank order metrics for quantifying the association of sequence features with gene regulation. 
  • Rapid decline of GABAA receptor subunit mRNA expression in hippocampus following transient cerebral ischemia in the gerbil. 
  • Rapid dendritic transport of TGN38, a putative cargo receptor. 
  • Ras enhances Myc protein stability. 
  • Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites. 
  • Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5-HT1A receptor via a G protein beta gamma-subunit-initiated pathway. 
  • Rat amylin: cloning and tissue-specific expression in pancreatic islets. 
  • Rat pancreatic kallikrein mRNA: nucleotide sequence and amino acid sequence of the encoded preproenzyme. 
  • Rat thecal/interstitial cells express transforming growth factor-beta type 1 and 2, but only type 2 is regulated by gonadotropin in vitro. 
  • Recent perspectives on the molecular structure and regulation of the beta 2-adrenoceptor. 
  • Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. 
  • Reconciling conflicting models for global control of cell-cycle transcription. 
  • Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. 
  • Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. 
  • Reconstructing regulatory network transitions. 
  • Recovery and expression of messenger RNA from postmortem human brain tissue. 
  • Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation. 
  • Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress. 
  • Redox regulation of mitochondrial biogenesis. 
  • Redox signaling: nitrosylation and related target interactions of nitric oxide. 
  • Redox-based regulation of signal transduction: principles, pitfalls, and promises. 
  • Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids. 
  • Regulated expression of a vitellogenin fusion gene in transgenic nematodes. 
  • Regulated expression of the tyrosine hydroxylase gene by epidermal growth factor. 
  • Regulated heat shock protein 27 expression in human retinal pigment epithelium. 
  • Regulating the regulator: NF-kappaB signaling in heart. 
  • Regulation of 2',5'-oligoadenylate synthetase gene expression by interferons and platelet-derived growth factor. 
  • Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage. 
  • Regulation of E2A gene expression in B-lymphocyte development. 
  • Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons. 
  • Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2. 
  • Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: the role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-kappaB. 
  • Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. 
  • Regulation of NF-kappaB action by reversible acetylation. 
  • Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system. 
  • Regulation of Sertoli cell differentiation by the testicular paracrine factor PModS: potential role of immediate-early genes. 
  • Regulation of T cell proliferation by JMJD6 and PDGF-BB during chronic hepatitis B infection. 
  • Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters. 
  • Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure. 
  • Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. 
  • Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene. 
  • Regulation of alpha-synuclein expression: implications for Parkinson's disease. 
  • Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators. 
  • Regulation of beta-cell glucose transporter gene expression. 
  • Regulation of cell division and of tyrosinase in B16 melanoma cells by imidazole: a possible role for the concept of metabolite gene regulation in mammalian cells. 
  • Regulation of cholecystokinin gene expression in rat intestine. 
  • Regulation of cholecystokinin synthesis and secretion in rat intestine. 
  • Regulation of chondrocytic gene expression by biomechanical signals. 
  • Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: role in mitogenesis and cell proliferation. 
  • Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium. 
  • Regulation of expression of transcobalamin II receptor in the rat. 
  • Regulation of gene expression in the lung. 
  • Regulation of gene expression is preserved in aging Drosophila melanogaster. 
  • Regulation of heat shock transcription factors and their roles in physiology and disease. 
  • Regulation of human nucleus pulposus cells by peptide-coupled substrates. 
  • Regulation of insulin secretion from novel engineered insulinoma cell lines. 
  • Regulation of interleukin-8 expression by cellular pH in human pancreatic adenocarcinoma cells. 
  • Regulation of lipoprotein lipase activity and mRNA in the mammary gland of the lactating mouse. 
  • Regulation of mucin genes in chronic inflammatory airway diseases. 
  • Regulation of neuroendocrine exocytosis by the ARF6 GTPase-activating protein GIT1. 
  • Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle. 
  • Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. 
  • Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. 
  • Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages. 
  • Regulation of platelet-activating factor synthesis in human neutrophils by MAP kinases. 
  • Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain. 
  • Regulation of receptor for advanced glycation end products during bleomycin-induced lung injury. 
  • Regulation of responsiveness at D2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization. 
  • Regulation of ribosomal protein synthesis in an Escherichia coli mutant missing ribosomal protein L1. 
  • Regulation of the Na/H exchanger regulatory factor in OK cells. 
  • Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. 
  • Regulation of the beta 2-adrenergic receptor and its mRNA in the rat ventral prostate by testosterone. 
  • Regulation of the cyclin E gene by transcription factor E2F1. 
  • Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone. 
  • Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein. 
  • Regulation of the human interleukin-3 gene. 
  • Regulation of the murine Ddelta2 promoter by upstream stimulatory factor 1, Runx1, and c-Myb. 
  • Regulation of the uncoupling protein-2 gene in INS-1 beta-cells by oleic acid. 
  • Regulation of tissue renin and angiotensin gene expressions. 
  • Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c. 
  • Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. 
  • Regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF-A) expression in podocytes. 
  • Regulation of vitellogenin gene expression in transgenic Caenorhabditis elegans: short sequences required for activation of the vit-2 promoter. 
  • Regulatory B10 cell development and function. 
  • Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. 
  • Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells. 
  • Regulatory elements governing transcription in specialized myofiber subtypes. 
  • Regulatory pathways governing HIV-1 replication. 
  • Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding. 
  • Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease. 
  • Relationship between serotonin transporter gene polymorphisms and platelet serotonin transporter sites among African-American cocaine-dependent individuals and healthy volunteers. 
  • Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice. 
  • Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression. 
  • Remaining flexible in old alliances: functional plasticity in constrained mutualisms. 
  • Renal systems biology of patients with systemic inflammatory response syndrome. 
  • Renin gene expression, biosynthesis, and cellular pathways of secretion. 
  • Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism. 
  • Repeated swim stress increases pain-induced expression of c-Fos in the rat lumbar cord. 
  • Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. 
  • Repression of interleukin-2 mRNA translation in primary human breast carcinoma tumor-infiltrating lymphocytes. 
  • Reproductive factors in relation to breast cancer characterized by p53 protein expression (United States). 
  • Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins. 
  • Requirement for Abl kinases in T cell receptor signaling. 
  • Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells. 
  • Resistance to apoptosis, increased growth potential, and altered gene expression in cells that survived genotoxic hexavalent chromium [Cr(VI)] exposure. 
  • Response of zonal chondrocytes to extracellular matrix-hydrogels. 
  • Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity. 
  • Retinoic acid receptors: transcription factors modulating gene regulation, development, and differentiation. 
  • Retinoic acid-mediated G1-S-phase arrest of normal human mammary epithelial cells is independent of the level of p53 protein expression. 
  • Retinoids and mouse embryonic development. 
  • Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300. 
  • Retroviral vector gene expression in F9 embryonal carcinoma cells. 
  • Retroviral vector-mediated transfer of the bacterial neomycin resistance gene into fetal and adult sheep and human hematopoietic progenitors in vitro. 
  • Reverse engineering gene regulatory networks. 
  • Reversing adipocyte differentiation: implications for treatment of obesity. 
  • Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. 
  • Riboswitches--to kill or save the messenger. 
  • Right ventricular hypertrophy with early dysfunction: A proteomics study in a neonatal model. 
  • Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: using decoy approach against AP-1 binding site. 
  • Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. 
  • Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. 
  • Role of co-regulators in metabolic and transcriptional actions of thyroid hormone. 
  • Role of interleukin-1beta in postoperative cognitive dysfunction. 
  • Role of miR-204 in the regulation of apoptosis, endoplasmic reticulum stress response, and inflammation in human trabecular meshwork cells. 
  • Role of miR-29b on the regulation of the extracellular matrix in human trabecular meshwork cells under chronic oxidative stress. 
  • Role of microRNAs in the trabecular meshwork. 
  • Role of molecular biology in hypertension research. State of the Art lecture. 
  • Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. 
  • Role of murine intestinal interleukin-1 receptor 1-expressing lymphoid tissue inducer-like cells in Salmonella infection. 
  • Role of natural product diversity in chemical biology. 
  • Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells. 
  • Role of the midbrain dopaminergic system in modulation of vocal brain activation by social context. 
  • Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection. 
  • Rosiglitazone induces mitochondrial biogenesis in mouse brain. 
  • Rudimentary substrates for vocal learning in a suboscine. 
  • S-nitrosylating agents: a novel class of compounds that increase cystic fibrosis transmembrane conductance regulator expression and maturation in epithelial cells. 
  • S-nitrosylation in the regulation of gene transcription. 
  • S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4. 
  • SETting the stage. Eed-Enx1 leaves an epigenetic signature on the inactive X chromosome. 
  • SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model. 
  • SOCS1, SOCS3, and PIAS1 promote myogenic differentiation by inhibiting the leukemia inhibitory factor-induced JAK1/STAT1/STAT3 pathway. 
  • SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane. 
  • SR proteins control a complex network of RNA-processing events. 
  • SRA coactivation of estrogen receptor-alpha is phosphorylation-independent, and enhances 4-hydroxytamoxifen agonist activity. 
  • STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration. 
  • SV40 enhancer-binding factors are required at the establishment but not the maintenance step of enhancer-dependent transcriptional activation. 
  • Salt restriction leads to activation of adult renal mesenchymal stromal cell-like cells via prostaglandin E2 and E-prostanoid receptor 4. 
  • Sarin causes early differential alteration and persistent overexpression in mRNAs coding for glial fibrillary acidic protein (GFAP) and vimentin genes in the central nervous system of rats. 
  • Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine. 
  • Scleral micro-RNA signatures in adult and fetal eyes. 
  • Screening of the Seed Region of MIR184 in Keratoconus Patients from Saudi Arabia. 
  • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 
  • Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. 
  • Searching for transcriptional regulators of Ang II-induced vascular pathology. 
  • Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. 
  • Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway. 
  • Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. 
  • Select de novo gene and protein expression during renal epithelial cell culture in rotating wall vessels is shear stress dependent. 
  • Selection and validation of endogenous reference genes using a high throughput approach. 
  • Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes. 
  • Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB. 
  • Selective expansion of allogeneic regulatory T cells by hepatic stellate cells: role of endotoxin and implications for allograft tolerance. 
  • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. 
  • Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. 
  • Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. 
  • Sensing and integration of Erk and PI3K signals by Myc. 
  • Sensitization of tumor cells to fas killing through overexpression of heat-shock transcription factor 1. 
  • Separate pathways for p53 induction by ionizing radiation and N-(phosphonoacetyl)-L-aspartate. 
  • Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation. 
  • Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression. 
  • Serotonin depletion exacerbates changes in striatal gene expression following quinolinic acid injection. 
  • Serotonin transporter gene moderates the development of emotional problems among children following bullying victimization. 
  • Serotonin- and training-induced dynamic regulation of CREB2 in Aplysia. 
  • Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats. 
  • Sex Differences in Gene and Protein Expression After Intracerebral Hemorrhage in Mice. 
  • Shigella dysenteriae modulates BMP pathway to induce mucin gene expression in vivo and in vitro. 
  • Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes. 
  • Simulating natural conditions in the laboratory: a re-examination of sexual isolation between sympatric and allopatric populations of Drosophila pseudoobscura and D. persimilis. 
  • Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α. 
  • Single-walled carbon nanotubes increase pandemic influenza A H1N1 virus infectivity of lung epithelial cells. 
  • Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants. 
  • Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2. 
  • Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis. 
  • Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. 
  • Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta. 
  • Small changes in expression affect predisposition to tumorigenesis. 
  • Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation. 
  • Smoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancy. 
  • Social environmental effects on gene regulation. 
  • Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaques. 
  • Social status alters immune regulation and response to infection in macaques. 
  • Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis. 
  • Somatostatin regulates duodenal cholecystokinin and somatostatin messenger RNA. 
  • Some nuts are tougher to crack than others. 
  • Some things I thought I knew about tissue factor that turn out to be wrong. 
  • Sorting human beta-cells consequent to targeted expression of green fluorescent protein. 
  • Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis. 
  • Spatial preferences of microRNA targets in 3' untranslated regions. 
  • Spatially restricted patterns of expression of the homeobox-containing gene Hox 2.1. during mouse embryogenesis. 
  • Specialized motor-driven dusp1 expression in the song systems of multiple lineages of vocal learning birds. 
  • Spermatogonial depletion in adult Pin1-deficient mice. 
  • Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology. 
  • Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells. 
  • Spinal cord trauma activates processing of xbp1 mRNA indicative of endoplasmic reticulum dysfunction. 
  • Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1. 
  • Spontaneous delta- to beta-globin switching in K562 human leukemia cells. 
  • Spreading depression activates unfolded protein response. 
  • Stable production of an analog of human tissue plasminogen activator from cultured Drosophila cells. 
  • Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation. 
  • Stage-specific expression of B cell translocation gene 1 in rat testis. 
  • Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost. 
  • Staphylococcus aureus sepsis induces early renal mitochondrial DNA repair and mitochondrial biogenesis in mice. 
  • Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling. 
  • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. 
  • Stathmin-deficient mice develop an age-dependent axonopathy of the central and peripheral nervous systems. 
  • Stbd1 is highly elevated in skeletal muscle of Pompe disease mice but suppression of its expression does not affect lysosomal glycogen accumulation. 
  • Steroidogenic factor 1: an essential mediator of endocrine development. 
  • Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa. 
  • Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo. 
  • Stochasticity in transcriptional regulation: origins, consequences, and mathematical representations. 
  • Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. 
  • Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. 
  • Structural analysis of the human BIN1 gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing. 
  • Structural and functional studies of cyclic GMP phosphodiesterase. 
  • Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia. 
  • Structural basis for the differential regulation of DNA by the methionine repressor MetJ. 
  • Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing. 
  • Structure and regulation of the murine Clara cell secretory protein gene. 
  • Studies of the lethargic (lh/lh) mouse model of absence seizures: regulatory mechanisms and identification of the lh gene. 
  • Subcellular localization of the human immunodeficiency virus trans-acting art gene product. 
  • Superimmunity: characterization of a new gene in the immunity region of P1. 
  • Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. 
  • Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. 
  • Suppression of food intake by glucagon-like peptide-1 receptor agonists: relative potencies and role of dipeptidyl peptidase-4. 
  • Suppression of the NF-κB pathway by diesel exhaust particles impairs human antimycobacterial immunity. 
  • Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice. 
  • Surface projections of titanium substrates increase antithrombotic endothelial function in response to shear stress. 
  • Surfactant protein A modulates induction of regulatory T cells via TGF-β. 
  • Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis. 
  • Sustained in vivo gene delivery from agarose hydrogel prolongs nonviral gene expression in skin. 
  • Sustained-input switches for transcription factors and microRNAs are central building blocks of eukaryotic gene circuits. 
  • Synergism of accessory factors in functional expression of mammalian odorant receptors. 
  • Synergistic effect of shear stress and streptavidin-biotin on the expression of endothelial vasodilator and cytoskeleton genes. 
  • Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3. 
  • Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter. 
  • Synergy in efficacy of fungal entomopathogens and permethrin against West African insecticide-resistant Anopheles gambiae mosquitoes. 
  • Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition. 
  • Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. 
  • Systematic binding analysis of the insulin gene transcription control region: insulin and immunoglobulin enhancers utilize similar transactivators. 
  • Systematic morphological profiling of human gene and allele function via Cell Painting. 
  • Systemic and Persistent Muscle Gene Expression in Rhesus Monkeys with a Liver De-Targeted Adeno-Associated Virus Vector. 
  • Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse. 
  • Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors. 
  • Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer. 
  • T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms. 
  • T cell development: better living through chromatin. 
  • T lymphocytes from chronic HCV-infected patients are primed for activation-induced apoptosis and express unique pro-apoptotic gene signature. 
  • T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex. 
  • T-bet-dependent expression of osteopontin contributes to T cell polarization. 
  • T-cell-directed cancer vaccines: the melanoma model. 
  • T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair. 
  • T3 or not T3--the slings and arrows of outrageous TR function. 
  • TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations. 
  • TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. 
  • TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. 
  • TGF-β-Regulated MicroRNAs and Their Function in Cancer Biology. 
  • TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2. 
  • TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. 
  • TNF, IFN-gamma, and endotoxin increase expression of DMT1 in bronchial epithelial cells. 
  • TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors. 
  • TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. 
  • TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. 
  • TSC-36 (follistatin-related polypeptide) gene expression in estrogen receptor positive osteoblastic cell line, CDO7F. 
  • Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. 
  • Targeted inhibition of V(D)J recombination by a histone methyltransferase. 
  • Targeted lymphoid homing of dendritic cells is required for prolongation of allograft survival. 
  • Targeted resequencing identifies PTCH1 as a major contributor to ocular developmental anomalies and extends the SOX2 regulatory network. 
  • Targeting of integrin beta1 and kinesin 2alpha by microRNA 183. 
  • Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro. 
  • Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. 
  • Tau--an inhibitor of deacetylase HDAC6 function. 
  • Temperature-sensitive TREK currents contribute to setting the resting membrane potential in embryonic atrial myocytes. 
  • Temperature-sensitive mRNA degradation is an early event in hepatocyte de-differentiation. 
  • Temporal and tissue-specific expression of distinct retrovirus-like (VL30) elements during mouse development. 
  • Temporal specific patterns of semaphorin gene expression in rat brain after kainic acid-induced status epilepticus. 
  • Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion. 
  • Tenascin-C inhibits extracellular matrix-dependent gene expression in mammary epithelial cells. Localization of active regions using recombinant tenascin fragments. 
  • Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation. 
  • The 5'-untranslated region of the N-methyl-D-aspartate receptor NR2A subunit controls efficiency of translation. 
  • The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3. 
  • The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. 
  • The Bardet-Biedl syndrome-related protein CCDC28B modulates mTORC2 function and interacts with SIN1 to control cilia length independently of the mTOR complex. 
  • The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells. 
  • The Ca2+-binding protein parvalbumin: molecular cloning and developmental regulation of mRNA abundance. 
  • The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. 
  • The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. 
  • The DVR gene family in embryonic development. 
  • The DXS423E gene in Xp11.21 escapes X chromosome inactivation. 
  • The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. 
  • The Drosophila copper transporter Ctr1C functions in male fertility. 
  • The E2F transcription factor is a cellular target for the RB protein. 
  • The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. 
  • The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate. 
  • The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity. 
  • The Krüppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. 
  • The Local Edge Machine: inference of dynamic models of gene regulation. 
  • The Lutheran glycoprotein: a multifunctional adhesion receptor. 
  • The NF-E2 transcription factor. 
  • The PICALM protein plays a key role in iron homeostasis and cell proliferation. 
  • The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. 
  • The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2. 
  • The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice. 
  • The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia. 
  • The TOR kinases link nutrient sensing to cell growth. 
  • The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. 
  • The acute promyelocytic leukaemia-associated PML gene is induced by interferon. 
  • The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease. 
  • The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation. 
  • The avian cardiac alpha-actin promoter is regulated through a pair of complex elements composed of E boxes and serum response elements that bind both positive- and negative-acting factors. 
  • The balance of benefit and safety of rosiglitazone: important lessons for our system of drug development and postmarketing assessment. 
  • The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease. 
  • The biological significance of substrate inhibition: a mechanism with diverse functions. 
  • The biomarker niche for fibroblast growth factor 23 testing in CKD. 
  • The chemokine CX3CL1 regulates NK cell activity in vivo. 
  • The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes. 
  • The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression. 
  • The coactivator SRC-1 is an essential coordinator of hepatic glucose production. 
  • The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure. 
  • The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity. 
  • The differential expression of IL-4 and IL-13 and its impact on type-2 immunity. 
  • The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. 
  • The dishevelled protein is modified by wingless signaling in Drosophila. 
  • The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. 
  • The dusp1 immediate early gene is regulated by natural stimuli predominantly in sensory input neurons. 
  • The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. 
  • The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster. 
  • The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance. 
  • The evolution of transcriptional regulation in eukaryotes. 
  • The evolutionary significance of cis-regulatory mutations. 
  • The expression of viral and cellular genes in papillomas of the choroid plexus induced in transgenic mice. 
  • The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure. 
  • The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. 
  • The g-value paradox. 
  • The genetic regulatory signature of type 2 diabetes in human skeletal muscle. 
  • The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2. 
  • The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. 
  • The helix-loop-helix gene E2A is required for B cell formation. 
  • The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming. 
  • The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. 
  • The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. 
  • The homeodomain protein HOXB13 regulates the cellular response to androgens. 
  • The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution. 
  • The human keratin genes and their differential expression. 
  • The human olfactory transcriptome. 
  • The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes. 
  • The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background. 
  • The indolocarbazole Gö6976 protects neurons from lipopolysaccharide/interferon-gamma-induced cytotoxicity in murine neuron/glia co-cultures. 
  • The influence of maternal body mass index on myometrial oxytocin receptor expression in pregnancy. 
  • The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes. 
  • The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy. 
  • The iron transporter DMT1. 
  • The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 families. 
  • The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing. 
  • The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. 
  • The manganese(III) porphyrin MnTnHex-2-PyP5+ modulates intracellular ROS and breast cancer cell migration: Impact on doxorubicin-treated cells. 
  • The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. 
  • The mitochondrial cyanide-resistant oxidase: structural conservation amid regulatory diversity. 
  • The mouse Sb1.8 gene located at the distal end of the X chromosome is subject to X inactivation. 
  • The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor. 
  • The myoD gene family: nodal point during specification of the muscle cell lineage. 
  • The nature and significance of differential keratin gene expression. 
  • The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair. 
  • The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus. 
  • The new age of medical genomics. 
  • The new collagen gene COL27A1 contains SOX9-responsive enhancer elements. 
  • The origin of spicule-forming cells in a 'primitive' sea urchin (Eucidaris tribuloides) which appears to lack primary mesenchyme cells. 
  • The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages. 
  • The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. 
  • The p53-dependent gamma-ray response of GADD45. 
  • The pallial basal ganglia pathway modulates the behaviorally driven gene expression of the motor pathway. 
  • The potential of DISC1 protein as a therapeutic target for mental illness. 
  • The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation. 
  • The relations of major platelet receptor expression during myocardial infarction. Monitoring efficacy of GPIIb/IIIa inhibitors by measuring P-selectin? 
  • The relationship of modulation of major histocompatibility complex class I antigens to retrovirus transformation in rat cell lines. 
  • The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9. 
  • The ribonome: a dominant force in co-ordinating gene expression. 
  • The role of Bcl-xL in mouse RPE cell survival. 
  • The role of Ctr1 and Ctr2 in mammalian copper homeostasis and platinum-based chemotherapy. 
  • The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases. 
  • The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection. 
  • The role of avian retroviral LTRs in the regulation of gene expression and viral replication. 
  • The role of cytokines in posttraumatic arthritis. 
  • The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo. 
  • The role of modulatory calcineurin-interacting proteins in calcineurin signaling. 
  • The role of the receptor for advanced glycation end-products in a murine model of silicosis. 
  • The role of tuberous sclerosis complex 1 in regulating innate immunity. 
  • The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death. 
  • The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease. 
  • The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. 
  • The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1. 
  • The transcription factor HLH-2/E/Daughterless regulates anchor cell invasion across basement membrane in C. elegans. 
  • The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. 
  • The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors. 
  • The upstream enhancer elements of the G6PC promoter are critical for optimal G6PC expression in murine glycogen storage disease type Ia. 
  • Three periods of regulatory innovation during vertebrate evolution. 
  • Thrombogenesis in atrial fibrillation contributing mechanisms and natural history. 
  • Thymic expression of the transcription factor Nur77 rescues the T cell but not the B cell abnormality of gld/gld mice. 
  • Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. 
  • Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner. 
  • Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. 
  • Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation. 
  • Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish. 
  • Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. 
  • Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences. 
  • Tissue-specific expression of the mammalian bombesin gene. 
  • Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells. 
  • Topical capsaicin treatment suppresses formalin-induced fos expression in rat spinal cord. 
  • Topographic specificity within membranes of a single muscle detected in vitro. 
  • Topology and control of the cell-cycle-regulated transcriptional circuitry. 
  • Toward an understanding of the functional complexity of the E2F and retinoblastoma families. 
  • Toward computational systems biology. 
  • Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events. 
  • Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism. 
  • Trans-kingdom small RNA transfer during host-pathogen interactions: The case of P. falciparum and erythrocytes. 
  • Transactivation by the adenovirus E1A gene. 
  • Transcription and processing of human microRNA precursors. 
  • Transcription factor NF-kappaB regulates inducible CD83 gene expression in activated T lymphocytes. 
  • Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans. 
  • Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo. 
  • Transcription factor p53 influences microglial activation phenotype. 
  • Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. 
  • Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level. 
  • Transcription interruption may be a common mechanism of c-myc regulation during HL-60 differentiation. 
  • Transcription of class III genes: formation of preinitiation complexes. 
  • Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells. 
  • Transcriptional activation of p21(waf1/cip1) by alkylphospholipids: role of the mitogen-activated protein kinase pathway in the transactivation of the human p21(waf1/cip1) promoter by Sp1. 
  • Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity. 
  • Transcriptional and functional profiles of voltage-gated Na(+) channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain. 
  • Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. 
  • Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. 
  • Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. 
  • Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. 
  • Transcriptional down-regulation of tumor necrosis factor-alpha gene expression by a synthetic peptide homologous to retroviral envelope protein. 
  • Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus. 
  • Transcriptional interference in avian retroviruses--implications for the promoter insertion model of leukaemogenesis. 
  • Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants. 
  • Transcriptional regulation by the numbers: applications. 
  • Transcriptional regulation by the numbers: models. 
  • Transcriptional regulation of changes in growth, cell cycle, and gene expression of Saccharomyces cerevisiae due to changes in buoyancy. 
  • Transcriptional regulation of crystallin, redox, and apoptotic genes by C-Phycocyanin in the selenite-induced cataractogenic rat model. 
  • Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1. 
  • Transcriptional regulation of the human T cell receptor delta gene. 
  • Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region. 
  • Transcriptional regulation of the mouse presenilin-1 gene. 
  • Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP. 
  • Transfection in the third dimension. 
  • Transfection of a human cytochrome P-450 gene into the human lymphoblastoid cell line, AHH-1, and use of the recombinant cell line in gene mutation assays. 
  • Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL. 
  • Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. 
  • Transforming growth factor-beta1 antisense treatment of rat vein grafts reduces the accumulation of collagen and increases the accumulation of h-caldesmon. 
  • Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans. 
  • Transgenic animals. New approaches to hypertension research. 
  • Transgenic indicator mice for studying activated retinoic acid receptors during development. 
  • Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles. 
  • Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch. 
  • Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism. 
  • Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice. 
  • Transient regulation of c-fos, alpha B-crystallin, and hsp70 in muscle during recovery from contractile activity. 
  • Translational control of phage f1 gene expression by differential activities of the gene V, VII, IX and VIII initiation sites. 
  • Transmembrane sema4E guides branchiomotor axons to their targets in zebrafish. 
  • Transposable elements: targets for early nutritional effects on epigenetic gene regulation. 
  • Transposed LEU2 gene of Saccharomyces cerevisiae is regulated normally. 
  • Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers. 
  • Triphenyl phosphate-induced developmental toxicity in zebrafish: potential role of the retinoic acid receptor. 
  • TrkB activation by 7, 8-dihydroxyflavone increases synapse AMPA subunits and ameliorates spatial memory deficits in a mouse model of Alzheimer's disease. 
  • Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice. 
  • Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide. 
  • Tumor necrosis factor alpha gene expression in human peritoneal macrophages is suppressed by extra-abdominal trauma. 
  • Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. 
  • Tumor necrosis factor-alpha induces increased hydrogen peroxide production and Fc receptor expression, but not increased Ia antigen expression by peritoneal macrophages. 
  • Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase. 
  • Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. 
  • Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. 
  • Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. 
  • UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner. 
  • Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis. 
  • Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3. 
  • Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro. 
  • Unmasking a role for sex chromosomes in gene silencing. 
  • Unmodern Synthesis: Developmental Hierarchies and the Origin of Phenotypes. 
  • Unveiling the secrets to her heart. 
  • Up-regulated expression of extracellular matrix remodeling genes in phagocytically challenged trabecular meshwork cells. 
  • Up-regulation of SNCA gene expression: implications to synucleinopathies. 
  • Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells. 
  • Upregulation of AKT1 protein expression in forskolin-stimulated macrophage: evidence from ChIP analysis that CREB binds to and activates the AKT1 promoter. 
  • Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis. 
  • Upregulation of molecules associated with T-regulatory function by thymoglobulin pretreatment of human CD4+ cells. 
  • Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening. 
  • Use of viral systems to study miRNA-mediated regulation of gene expression in human cells. 
  • Using whole mount in situ hybridization to examine thyroid hormone deiodinase expression in embryonic and larval zebrafish: a tool for examining OH-BDE toxicity to early life stages. 
  • Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture. 
  • VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. 
  • Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. 
  • Variables affecting the T cell receptor V beta repertoire heterogeneity of T cells infiltrating human renal allografts. 
  • Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. 
  • Variations in opsin coding sequences cause x-linked cone dysfunction syndrome with myopia and dichromacy. 
  • Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's Oncology Group. 
  • Vibratory loading decreases extracellular matrix and matrix metalloproteinase gene expression in rabbit annulus cells. 
  • Viral RNAs: lessons from the enemy. 
  • Viral sequences determining the oncogenicity of avian leukosis viruses. 
  • Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC. 
  • Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus. 
  • Viruses, microRNAs, and host interactions. 
  • Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis. 
  • WT1 and DAX-1 regulate SF-1-mediated human P450arom gene expression in gonadal cells. 
  • Water-soluble and nonionic polyphosphoester: synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle. 
  • What evidence is there for the existence of individual genes with antagonistic pleiotropic effects? 
  • Whole blood gene expression testing for coronary artery disease in nondiabetic patients: major adverse cardiovascular events and interventions in the PREDICT trial. 
  • Why do mutations in the ubiquitously expressed housekeeping gene IMPDH1 cause retina-specific photoreceptor degeneration? 
  • Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. 
  • Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. 
  • X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse. 
  • X-inactivation profile reveals extensive variability in X-linked gene expression in females. 
  • Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53. 
  • ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6. 
  • Zebrafish Transcription Factor ORFeome for Gene Discovery and Regulatory Network Elucidation. 
  • Zebrafish assays of ciliopathies. 
  • [Induction of synthesis specific for females of variants growth hormone receptor mRNA in liver of male rats]. 
  • [LMP-420, a new therapeutic approach for cerebral malaria?]. 
  • [Proto-oncogene and pain modulation]. 
  • [Using Hsp70 promoter to regulate target gene expression in tumor]. 
  • aFGF, bFGF and NGF differentially regulate neuropeptide expression in dorsal root ganglia after axotomy and induce autotomy. 
  • beta Adrenergic control of c-fos protooncogene expression in developing rat brain regions. 
  • beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase. 
  • beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. 
  • beta-Arrestin: a protein that regulates beta-adrenergic receptor function. 
  • beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. 
  • cCXCR1 is a receptor for cIL-8 (9E3/cCAF) and its N- and C-terminal peptides and is also activated by hIL-8 (CXCL8). 
  • cDNA expression arrays: the effects of lactacystin in lipopolysaccharide-induced cystitis. 
  • delta-9-Tetrahydrocannabinol regulates gene expression of the growth factor pleiotrophin in the forebrain. 
  • eNOS, a pressure-dependent regulator of intraocular pressure. 
  • mNos2 deletion and human NOS2 replacement in Alzheimer disease models. 
  • miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation. 
  • miR-181a is an intrinsic modulator of T cell sensitivity and selection. 
  • miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. 
  • microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. 
  • p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. 
  • p53 regulates the expression of the tumor suppressor gene maspin. 
  • ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress. 
  • α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration. 
  • β-Catenin modulation in neurofibromatosis type 1 bone repair: therapeutic implications. 
  • β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. 
• 

  Keywords of People

  • Alberts, Susan C., Robert F. Durden Professor of Biology, Duke Science & Society
  • Barfield, Raymond Carlton, Professor of Pediatrics, Duke Science & Society
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Cianciolo, George James, Associate Professor in Pathology, Pathology
  • Ciofani, Maria, Assistant Professor of Immunology, Immunology
  • Davis, Erica Ellen, Associate Professor of Pediatrics, Cell Biology
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hilton, Matthew James, Associate Professor in Orthopaedic Surgery, Cell Biology
  • Hirschey, Matthew, Associate Professor, Pharmacology & Cancer Biology
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology, Neuroanesthesia
  • Karhausen, Jorn, Assistant Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Kelsoe, Garnett H., James B. Duke Professor of Immunology, Immunology
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Immunology
  • McCall, Shannon Jones, Associate Professor of Pathology, Pathology
  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Olson, Steven Arthur, Professor of Orthopaedic Surgery, Orthopaedics
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics, Molecular Genetics and Microbiology
  • Sanchez-Perez, Luis Ariel, Assistant Professor of Neurosurgery, Neurosurgery
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Soderling, Scott Haydn, Professor in Cell Biology, Cell Biology
  • Sullivan, Beth Ann, Associate Professor of Molecular Genetics and Microbiology, Duke Science & Society
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Swartzwelder, Harry Scott, Professor in Psychiatry and Behavioral Sciences, Duke Science & Society
  • Tsalik, Ephraim, Associate Professor of Medicine, Molecular Genetics and Microbiology
  • Tung, Jenny, Associate Professor of Evolutionary Anthropology, Duke Science & Society
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Professor of Experimental Surgery, in the School of Medicine, Immunology
  • Wray, Gregory Allan, Professor of Biology, Duke Innovation & Entrepreneurship
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Yildirim, Eda, Assistant Professor of Cell Biology, Cell Biology
  • Zhong, Xiaoping, Professor of Pediatrics, Immunology