Genes

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  Subject Areas on Research

  • 5' flanking sequences of the rat tyrosine hydroxylase gene target accurate tissue-specific, developmental, and transsynaptic expression in transgenic mice. 
  • A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP. 
  • A candidate taste receptor gene near a sweet taste locus. 
  • A classification for genetic disorders of interest to orthopaedists. 
  • A cloned calmodulin structural gene probe is complementary to DNA sequences from diverse species. 
  • A human gamma globin gene variant binds SP1. 
  • A hyaline layer protein that becomes localized to the oral ectoderm and foregut of sea urchin embryos. 
  • A large-scale functional approach to uncover human genes and pathways in Drosophila. 
  • A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium. 
  • A molecular genetic linkage map of mouse chromosome 7. 
  • A mutation affecting expression of the gene coding for serine transacetylase in Salmonella typhimurium. 
  • A new phase in the study of human inherited eye diseases. 
  • A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene. 
  • A single genetic locus determines the efficacy of serum therapy against murine adenocarcinoma 755a. 
  • ALTERATIONS OF THE P53 GENE ARE ASSOCIATED WITH THE PROGRESSION OF A HUMAN PROSTATE CARCINOMA 
  • Activation and repression of mammalian gene expression by the c-myc protein. 
  • Alpha interferon and gamma interferon stimulate transcription of a single gene through different signal transduction pathways. 
  • Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome. 
  • Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing. 
  • Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect. 
  • Amanitin-resistant RNA polymerase II mutations are in the enzyme's largest subunit. 
  • An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins. 
  • Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. 
  • Analysis of lens cell fate and eye morphogenesis in transgenic mice ablated for cells of the lens lineage. 
  • Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila. 
  • Analysis of the junction between ribosomal RNA genes and single-copy chromosomal sequences in the yeast Saccharomyces cerevisiae. 
  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. 
  • Analysis of the mouse transcriptome for genes involved in the function of the nervous system. 
  • AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier. 
  • Arthropod relationships revealed by phylogenomic analysis of nuclear protein-coding sequences. 
  • Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. 
  • Assignment of human gamma crystallin multigene family to chromosome 2. 
  • Assignment of human transforming growth factor-beta type I and type III receptor genes (TGFBR1 and TGFBR3) to 9q33-q34 and 1p32-p33, respectively. 
  • Bacterial expression vectors for calmodulin. 
  • Bacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coli. 
  • Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids. 
  • Biodemographic trajectories of longevity. 
  • CD44--a molecule involved in leukocyte adherence and T-cell activation. 
  • Calmodulin as a mediator of hormone action and cell regulation. 
  • Calmodulin is involved in regulation of cell proliferation. 
  • Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene. 
  • Can three incongruence tests predict when data should be combined? 
  • Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene. 
  • Changes in microfilament organization and surface topogrophy upon transformation of chick embryo fibroblasts with Rous sarcoma virus. 
  • Characterization and expression of the complementary DNA encoding rat histidine decarboxylase. 
  • Characterization of a Drosophila U snRNP RNA-binding protein. 
  • Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21. 
  • Characterization of a cloned histone gene cluster of the newt Notophthalamus viridescens. 
  • Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase. 
  • Characterization of two types of yeast ribosomal DNA genes. 
  • Chicken calmodulin genes. A species comparison of cDNA sequences and isolation of a genomic clone. 
  • Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. 
  • Cholecystokinin cells. 
  • Chromosomal assignments of the genes coding for human types II, III, and IV collagen: a dispersed gene family. 
  • Chromosomal localization of the ankyrinG gene (ANK3/Ank3) to human 10q21 and mouse 10. 
  • Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. 
  • Cloning and expression of full-length cDNA encoding human vitamin D receptor. 
  • Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. 
  • Cloning of human androgen receptor complementary DNA and localization to the X chromosome. 
  • Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors. 
  • Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. 
  • Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes. 
  • Cloning of zebrafish vsx1: expression of a paired-like homeobox gene during CNS development. 
  • Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. 
  • Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and Multi-CSF (IL3). 
  • Coevolution of the major histocompatibility complex and the t-complex in the mouse. I. Generation and maintenance of high complementarity associations. 
  • Coevolution of the major histocompatibility complex and the t-complex in the mouse. II. Modification of response to sharing of histocompatibility antigens. 
  • Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins. 
  • Comparative analysis of the zeta-crystallin/quinone reductase gene in guinea pig and mouse. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. 
  • Complex structure and regulation of the ABP/SHBG gene. 
  • Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition. 
  • Covariation of branch lengths in phylogenies of functionally related genes. 
  • Cytoskeletal actin gene families of Xenopus borealis and Xenopus laevis. 
  • DNA sequence patents are not in the grave yet. 
  • DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2. 
  • Defending information-free genocentrism. 
  • Deletion of carboxy-terminal residues of murine granulocyte-macrophage colony-stimulating factor results in a loss of biologic activity and altered glycosylation. 
  • Development of mullerian inhibiting substance as an anti-cancer drug. 
  • Developmental and transformation-sensitive expression of the Sparc gene on mouse chromosome 11. 
  • Developmental regulation of mouse SPARC (osteonectin) gene expression. 
  • Dicistronic polioviruses as expression vectors for foreign genes. 
  • Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans. 
  • Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. 
  • Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia. 
  • Differential replication of ribosomal gene repeats in polytene nuclei of Drosophila. 
  • Direct regional assignment of the gene for vitamin D binding protein (Gc-globulin) to human chromosome 4q11-q13 and identification of an associated DNA polymorphism. 
  • Disease genes and chromosomes: disease maps of the human genome. Chromosome 9. 
  • Domain II of calmodulin is involved in activation of calcineurin. 
  • Downregulation of RNA polymerase III transcription of the hY3 gene in vitro. 
  • Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins. 
  • Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. 
  • Effects of cholecystokinin on pancreatic ornithine decarboxylase gene expression. 
  • Engineering soluble major histocompatibility molecules: why and how. 
  • Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth. 
  • Escherichia coli phage T4 topoisomerase. 
  • Eukaryotic gene transcription with purified components. 
  • Evidence for locus heterogeneity in the Bethlem myopathy and linkage to 2q37. 
  • Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene. 
  • Evidence that the ribosomal DNA genes of yeast are not on chromosome I. 
  • Evolution of a complex eukaryotic gene. 
  • Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes. 
  • Evolutionary mechanisms for eucaryotic genes. 
  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. 
  • Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction. 
  • Extensive junctional diversity of rearranged human T cell receptor delta genes. 
  • Food for thought: brain, genes, and nutrition. 
  • Formation of a rate-limiting intermediate in 5S RNA gene transcription. 
  • From anemia to cerebellar dysfunction. A review of the ankyrin gene family. 
  • Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly. 
  • Further characterization of erythrocyte p80 and the membrane protein defect of In(Lu) Lu(a-b-) erythrocytes. 
  • GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol. 
  • Gene A of X174. 1. Isolation and identification of its products. 
  • Gene Ontology annotations and resources. 
  • Gene expression phenotypes of atherosclerosis. 
  • Gene expression signatures that predict radiation exposure in mice and humans. 
  • Genes determining blood cell traits. 
  • Genetic and biochemical characterization of mutants at an RNA polymerase II locus in D. melanogaster. 
  • Genetic approaches for the investigation of genes associated with coronary heart disease. 
  • Genetic approaches to molecular motors. 
  • Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene. 
  • Genetic regulation of beta-adrenergic receptors. 
  • Genomic features that predict allelic imbalance in humans suggest patterns of constraint on gene expression variation. 
  • Genomic organization and polymorphism of human angiotensin II type 2 receptor: no evidence for its gene mutation in two families of human premature ovarian failure syndrome. 
  • Genomic organization of rat rDNA. 
  • Genomic structure and amino acid sequence domains of the human La autoantigen. 
  • HLA antigen structural gene mutants selected with an allospecific monoclonal antibody. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. 
  • Hb Catonsville (glutamic acid inserted between Pro-37(C2)alpha and Thr-38(C3)alpha). Nonallelic gene conversion in the globin system? 
  • Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. 
  • Histone gene clusters of the newt notophthalmus are separated by long tracts of satellite DNA. 
  • Histone genes are located at the sphere loci of newt lampbrush chromosomes. 
  • Humoral immune response to the entire human immunodeficiency virus envelope glycoprotein made in insect cells. 
  • Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. 
  • Identification and cell type specificity of the tyrosine hydroxylase gene promoter. 
  • Identification of a deletion in the adenosine deaminase gene in a child with severe combined immunodeficiency. 
  • Identification of a muscle-specific enhancer within the 5'-flanking region of the human myoglobin gene. 
  • Identification of a structural gene for a RNA polymerase II polypeptide in Drosophila melanogaster and mammalian species. 
  • Identification of additional members of human G-protein-coupled receptor kinase multigene family. 
  • Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men. 
  • Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions. 
  • Identification of genetic markers to 20 NIDDM candidate genes by radiation hybrid analysis. 
  • Identification of putative human T cell receptor delta complementary DNA clones. 
  • Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. 
  • Idiotypic determinants used in the analysis of antibody diversification and as regulatory targets. 
  • Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes. 
  • Impact of gene patents and licensing practices on access to genetic testing for cystic fibrosis. 
  • Impact of gene patents and licensing practices on access to genetic testing for inherited susceptibility to cancer: comparing breast and ovarian cancers with colon cancers. 
  • Impact of gene patents and licensing practices on access to genetic testing for long QT syndrome. 
  • Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. 
  • Inferring genetic ancestry: opportunities, challenges, and implications. 
  • Initial sequencing and analysis of the human genome. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis. 
  • Interactions between sustained contractile activity and beta-adrenergic receptors in regulation of gene expression in skeletal muscles. 
  • Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein. 
  • Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene. 
  • Interpreting microarray results with gene ontology and MeSH. 
  • Interrupter sequences that are widely distributed in the Drosophila genome. 
  • Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles. 
  • Investigation of the phenylethanolamine N-methyltransferase gene as a candidate gene for hypertension. 
  • Involvement of the S-layer proteins Hpi and SlpA in the maintenance of cell envelope integrity in Deinococcus radiodurans R1. 
  • Is there left-handed DNA at the ends of yeast chromosomes? 
  • Isolation and characterization of a human pro alpha 2(I) collagen gene segment. 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of cDNA clones encoding pig gastric mucin. 
  • Isolation and structural analysis of the chromosomal gene for chicken calmodulin. 
  • Isolation of a candidate cDNA for the gene causing retinal degeneration in the rd mouse. 
  • Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant. 
  • Isolation of a rat parvalbumin gene and full length cDNA. 
  • Isolation of human sequences that replicate autonomously in human cells. 
  • Isolation of the structural gene for calmodulin. 
  • Linkage analysis for age-related macular degeneration supports a gene on chromosome 10q26. 
  • Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse. 
  • Localisation of receptor interacting protein 140 (RIP140) within 100 kb of D21S13 on 21q11, a gene-poor region of the human genome. 
  • Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. 
  • Localization of three genes expressed in retina on mouse chromosome 11. 
  • Location and molecular cloning of D1 dopamine receptor. 
  • Location of the 5.8S rRNA gene of Saccharomyces cerevisiae. 
  • Location of the gene involving the small eye mutation on mouse chromosome 2 suggests homology with human aniridia 2 (AN2). 
  • Long poly(A) tracts in the human genome are associated with the Alu family of repeated elements. 
  • Lutheran antigens, CD44-related antigens, and Lutheran regulatory genes. 
  • Magnification of the ribosomal genes in female Drosophila melanogaster. 
  • Mechanical culture conditions effect gene expression: gravity-induced changes on the space shuttle. 
  • Meiotic mapping of yeast ribosomal deoxyribonucleic acid on chromosome XII. 
  • Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase. 
  • Methods for analyzing bovine papilloma virus-based calmodulin expression vectors. 
  • Methods for interaction analyses using family-based case-control data: conditional logistic regression versus generalized estimating equations. 
  • Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure. 
  • Mitochondrial malic enzyme in mosaic skeletal muscle of mouse chimeras. 
  • Mixed lymphocyte responses in a four-generation C2 deficiency family. 
  • Model selection in binary trait locus mapping. 
  • Modulation of microfilament protein composition by transfected cytoskeletal actin genes. 
  • Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33. 
  • Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R ) in the hairless gene (Hr). 
  • Molecular biology of adrenergic receptors. 
  • Molecular biology of the renin-angiotensin system. 
  • Molecular characterization of ribosomal genes on the Ybb- chromosome of Drosophila melanogaster. 
  • Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA. 
  • Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA. 
  • Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulus-response coupling. 
  • Molecular cloning of laminin. 
  • Molecular cloning of ovomucoid gene sequences from partially purified ovomucoid messenger RNA. 
  • Molecular cloning of sequences from a Drosophila RNA polymerase II locus by P element transposon tagging. 
  • Molecular cloning of the gene sequences of a major apoprotein in avian very low density lipoproteins. 
  • Molecular cloning sequence and distribution of rat calspermin, a high affinity calmodulin-binding protein. 
  • Molecular genetics of yeast. 
  • Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene. 
  • Molecular structure of the La and Ro autoantigens and their use in autoimmune diagnostics. 
  • Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines. 
  • Multifactorial/threshold models and their application to cleft lip and cleft palate. 
  • Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium. 
  • Multiple gastrin-releasing peptide gene-associated peptides are produced by a human small cell lung cancer line. 
  • Mutations in the maize mitochondrial T-urf13 gene eliminate sensitivity to a fungal pathotoxin. 
  • Myosin light chain kinase structure function analysis using bacterial expression. 
  • Nature of the 3'-terminal sequences of the plus and minus strands of the S1 gene of reovirus serotypes 1, 2 and 3. 
  • Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes. 
  • Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. 
  • Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert. 
  • Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains. 
  • Nucleotide sequence and high-level expression of the major Escherichia coli phosphofructokinase. 
  • Nucleotide sequence of a 5S ribosomal RNA gene in the sea urchin Lytechinus variegatus. 
  • Nucleotide sequence of the envelope protein genes of a highly virulent, neurotropic strain of Newcastle disease virus. 
  • Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences. 
  • On the association between genes and complex traits. 
  • On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. 
  • Ovalbumin gene: purification of the coding strand. 
  • Ovomucoid intervening sequences specify functional domains and generate protein polymorphism. 
  • Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment. 
  • Physiological implications of the presence, distribution, and regulation of calmodulin in eukaryotic cells. 
  • Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. 
  • Polytenization of the ribosomal genes on the X and Y chromosomes of Drosophila melanogaster. 
  • Practice and public policy in the era of gene-environment interactions. 
  • Preliminary evidence of linkage of salt sensitivity in black Americans at the beta 2-adrenergic receptor locus. 
  • Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein. 
  • Probable exclusion of GLC1A as a candidate glaucoma gene in a family with middle-age-onset primary open-angle glaucoma. 
  • Pseudo-von Willebrand disease: a mutation in the platelet glycoprotein Ib alpha gene associated with a hyperactive surface receptor. 
  • RNA-seq: impact of RNA degradation on transcript quantification. 
  • Rapid dissection of a complex phenotype through genomic-scale mapping of fitness altering genes. 
  • Recombination between genes located on nonhomologous chromosomes in Saccharomyces cerevisiae. 
  • Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes. 
  • Regional localization of the phosphoglycerate kinase gene and pseudogene on the human X chromosome and assignment of a related DNA sequence to chromosome 19. 
  • Regulated expression of p18, a major phosphoprotein of leukemic cells. 
  • Regulation of the human c-myc gene: 5' noncoding sequences do not affect translation. 
  • Regulation of tissue renin and angiotensin gene expressions. 
  • Regulatory genes linked to the albino locus in the mouse confer competence for inducible expression on the structural gene encoding serine dehydratase. 
  • Repeat polymorphisms within gene regions: phenotypic and evolutionary implications. 
  • Replicating circular DNA molecules in yeast. 
  • Report and abstracts of the sixth international workshop on human chromosome 1 mapping 2000. Iowa City, Iowa, USA. 30 September-3 October 2000. 
  • Report of the committee on the genetic constitution of chromosome 19. 
  • Report of the committee on the genetic constitution of chromosomes 18 and 19. 
  • Rh-related antigen CD47 is the signal-transducer integrin-associated protein. 
  • Role of the avian retrovirus mRNA leader in expression: evidence for novel translational control. 
  • Roles of wingless in patterning the larval epidermis of Drosophila. 
  • SGP-1: prediction and validation of homologous genes based on sequence alignments. 
  • Salmonella typhimurium SA host specificity system is based on deoxyribonucleic acid-adenine methylation. 
  • Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells. 
  • Segregation and linkage analysis of alpha-N-acetyl-D-glucosaminidase (NAG) levels in a black family. 
  • Selection and validation of endogenous reference genes using a high throughput approach. 
  • Selection of optimal reference genes for normalization in quantitative RT-PCR. 
  • Selective conservation of GAP-43 structure in vertebrate evolution. 
  • Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines. 
  • Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. 
  • Sequences within the spacer region of yeast rRNA cistrons that stimulate 35S rRNA synthesis in vivo mediate RNA polymerase I-dependent promoter and terminator activities. 
  • Simple Mendelian inheritance of the repeating yeast ribosomal DNA genes. 
  • Site-specific recognition of bacteriophage T4 DNA by T4 type II DNA topoisomerase and Escherichia coli DNA gyrase. 
  • Sites of P element insertion and structures of P element deletions in the 5' region of Drosophila melanogaster RpII215. 
  • Specific transforming potential of oncogenes encoding protein-tyrosine kinases. 
  • Spectrum of mutations in the Batten disease gene, CLN3. 
  • Steroid and high-temperature induction of the small heat-shock protein genes in Drosophila. 
  • Stimulation of cytoplasmic actin gene transcription and translation in cultured Drosophila cells by ecdysterone. 
  • Strategies for analysis of gene expression: pulmonary surfactant proteins. 
  • Structural organization and chromosomal assignment of the parvalbumin gene. 
  • Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes. 
  • Structure and evolution of prokaryotic and eukaryotic RNA polymerases: a model. 
  • Structure and regulation of the murine Clara cell secretory protein gene. 
  • Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein. 
  • Structure of the eukaryotic transcription apparatus: features of the gene for the largest subunit of Drosophila RNA polymerase II. 
  • Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1). 
  • Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes. 
  • Studies of viral antibody responses among Amish families. 
  • Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct. 
  • T-cell receptors of human suppressor cells. 
  • T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. 
  • The DNA sequence and biological annotation of human chromosome 1. 
  • The Disease and Gene Annotations (DGA): an annotation resource for human disease. 
  • The Gene Ontology (GO) database and informatics resource. 
  • The Gene Ontology (GO) project in 2006. 
  • The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis. 
  • The Perils of Taking Property Too Far 
  • The cardiofaciocutaneous syndrome. 
  • The chick ovomucoid gene contains at least six intervening sequences. 
  • The gamma delta T cell receptor. 
  • The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. 
  • The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse. 
  • The genome of the sea urchin Strongylocentrotus purpuratus. 
  • The human genes for S-adenosylhomocysteine hydrolase and adenosine deaminase are syntenic on chromosome 20. 
  • The human glycine receptor: a new probe that is linked to the X-linked hypophosphatemic rickets gene. 
  • The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors. 
  • The immunogenetics of the major histocompatibility chromosomal region in man. 
  • The isolation of ecdysterone inducible genes by hybridization subtraction chromatography. 
  • The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. 
  • The mast cell-specific expression of a protease gene, RMCP II, is regulated by an enhancer element that binds specifically to mast cell trans-acting factors. 
  • The natural 5' splice site of simian virus 40 large T antigen can be improved by increasing the base complementarity to U1 RNA. 
  • The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. 
  • The ovalbumin gene. Partial purification of the coding strand. 
  • The poliovirus sensitivity (PVS) gene is on chromosome 19q12----q13.2. 
  • The polymorphic locus for glycogen storage disease VI (liver glycogen phosphorylase) maps to chromosome 14. 
  • The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila. 
  • Tissue specificity of renin promoter activity and regulation in mice. 
  • Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences. 
  • Tissue-specific expression of the mammalian bombesin gene. 
  • Tissue-specific gene expression in mouse F9 embryonal carcinoma cells: type IV collagen. 
  • Transcript length heterogeneity at the small heat shock protein genes of Drosophila. 
  • Transcription of H-2 and Qa genes in embryonic and adult mice. 
  • Transcription of class III genes: formation of preinitiation complexes. 
  • Transcription of spacer sequences flanking the rat 45S ribosomal DNA gene. 
  • Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP. 
  • Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. 
  • Two proteins of gene A of psiX174. 
  • Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. 
  • Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. 
  • Use of a CEPH meiotic breakpoint panel to refine the locus of limb-girdle muscular dystrophy type 1A (LGMD1A) to a 2-Mb interval on 5q31. 
  • Use of eukaryotic expression technology in the functional analysis of cloned genes. 
  • Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily. 
  • Who owns the genome? 
  • Whole-genome analyses resolve early branches in the tree of life of modern birds. 
  • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. 
  • Yeast ribosomal DNA genes are located on chromosome XII. 
  • apex: phylogenetics with multiple genes. 
  • cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure. 
  • lac repressor blocks in vivo transcription of lac control region DNA. 
  • rqt: an R package for gene-level meta-analysis. 
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  Keywords of People

  • Aballay, Alejandro, Adjunct Professor in the Department of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • Dodge, Kenneth A., Pritzker Professor of Early Learning Policy Studies, Duke Science & Society
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Schmid, Amy K., Associate Professor of Biology, Duke Science & Society
  • Wray, Gregory Allan, Professor of Biology, Duke Innovation & Entrepreneurship