Genes, Bacterial

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  Subject Areas on Research

  • 50 million years of genomic stasis in endosymbiotic bacteria. 
  • A hag mutant of Moraxella catarrhalis strain O35E is deficient in hemagglutination, autoagglutination, and immunoglobulin D-binding activities. 
  • A histidine protein kinase homologue required for regulation of bacterial cell division and differentiation. 
  • A new dominant selectable marker for use in Cryptococcus neoformans. 
  • A novel thermostable branching enzyme from an extremely thermophilic bacterial species, Rhodothermus obamensis. 
  • A single base substitution in the variable pocket of yeast tRNA(Arg) eliminates species-specific aminoacylation. 
  • A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes. 
  • Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy. 
  • Adhesin presentation in bacteria requires molecular chaperones and ushers. 
  • An in vivo expression technology screen for Vibrio cholerae genes expressed in human volunteers. 
  • Analysis of the genotype and virulence of Staphylococcus epidermidis isolates from patients with infective endocarditis. 
  • Application of a moving bed biofilm reactor for tertiary ammonia treatment in high temperature industrial wastewater. 
  • Applications of gene fusions to green fluorescent protein and flow cytometry to the study of bacterial gene expression in host cells. 
  • Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins. 
  • Association of molybdopterin guanine dinucleotide with Escherichia coli dimethyl sulfoxide reductase: effect of tungstate and a mob mutation. 
  • Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients. 
  • Bacterial infection remains a leading cause of death in both Western and developing world. Preface. 
  • Base changes at position 792 of Escherichia coli 16S rRNA affect assembly of 70S ribosomes. 
  • Bayesian learning from marginal data in bionetwork models. 
  • Binding of bacteria to mucosal surfaces. 
  • Broad host range vectors for stable genomic library construction. 
  • C-terminally truncated derivatives of Escherichia coli Hfq are proficient in riboregulation. 
  • Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. 
  • Characterization of Mycobacterium montefiorense sp. nov., a novel pathogenic Mycobacterium from moray eels that is related to Mycobacterium triplex. 
  • Characterization of a major cluster of nif, fix, and associated genes in a sugarcane endophyte, Acetobacter diazotrophicus. 
  • Characterization of the DNA- and metal-binding properties of Vibrio anguillarum fur reveals conservation of a structural Zn(2+) ion. 
  • Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase. 
  • Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates. 
  • Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, prochlorococcus. 
  • Chromosomal organization of rRNA operons in Bacillus subtilis. 
  • Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes. 
  • Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster. 
  • Comparison of the evolutionary dynamics of symbiotic and housekeeping loci: a case for the genetic coherence of rhizobial lineages. 
  • Complete genomic nucleotide sequence of the temperate bacteriophage Aa Phi 23 of Actinobacillus actinomycetemcomitans. 
  • Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes. 
  • Conserved economics of transcription termination in eubacteria. 
  • Construction of a fluorescent biosensor family. 
  • Contribution of aerobic photoheterotrophic bacteria to the carbon cycle in the ocean. 
  • Cyanobacterial ribosomal RNA genes with multiple, endonuclease-encoding group I introns. 
  • Cytosine deamination in mismatched base pairs. 
  • DNA bending near the replication origin of IncFII plasmid NR1. 
  • DNA nicks inflicted by restriction endonucleases are repaired by a RecA- and RecB-dependent pathway in Escherichia coli. 
  • DNA sequences of the cysK regions of Salmonella typhimurium and Escherichia coli and linkage of the cysK regions to ptsH. 
  • Decay of mutualistic potential in aphid endosymbionts through silencing of biosynthetic loci: Buchnera of Diuraphis. 
  • Deep divergence and rapid evolutionary rates in gut-associated Acetobacteraceae of ants. 
  • Determinations of restriction fragment length polymorphism in bacteria using ribosomal RNA genes. 
  • Discrimination of tRNALeu isoacceptors by the insertion mutant of Escherichia coli leucyl-tRNA synthetase. 
  • Dissimilatory sulphite reductase from Archaeoglobus fulgidus: physico-chemical properties of the enzyme and cloning, sequencing and analysis of the reductase genes. 
  • Dominant selection system for use in Cryptococcus neoformans. 
  • DsbB is required for the pathogenesis process of Xanthomonas campestris pv. campestris. 
  • Dual infection with Ehrlichia chaffeensis and a spotted fever group rickettsia: a case report. 
  • Ecology drives a global network of gene exchange connecting the human microbiome. 
  • Effect of isopropyl-beta-D-thiogalactopyranosid induction of the lac operon on the specificity of spontaneous and doxorubicin-induced mutations in Escherichia coli. 
  • Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular Pathogen. 
  • Engineering multicellular systems by cell-cell communication. 
  • Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs. 
  • Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction. 
  • Evaluation of the accuracy and reproducibility of a practical PCR panel assay for rapid detection and differentiation of Mycobacterium avium subspecies. 
  • Evidence for capsule gene sequences among pharyngeal isolates of nontypeable Haemophilus influenzae. 
  • Evidence for genetic drift in endosymbionts (Buchnera): analyses of protein-coding genes. 
  • Examining relationships between total silver concentration and Sil silver resistance genes in domestic wastewater treatment plants. 
  • Excision and transposition of Tn5 as an SOS activity in Escherichia coli. 
  • Exploitation of macrophages as a replication niche by Legionella pneumophila: response. 
  • Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature. 
  • Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. 
  • FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria. 
  • Fine-scale phylogenetic architecture of a complex bacterial community. 
  • Functional Advantages of Porphyromonas gingivalis Vesicles. 
  • Functional amyloid in Pseudomonas. 
  • Further evidence that transposition of Tn5 in Escherichia coli is strongly enhanced by constitutively activated RecA proteins. 
  • Generation of isogenic K54 capsule-deficient Escherichia coli strains through TnphoA-mediated gene disruption. 
  • Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene. 
  • Genetic structure and DNA sequences at junctions involved in the rearrangements of Bacillus subtilis strains carrying the trpE26 mutation. 
  • Genetic variability of Bacillus anthracis and related species. 
  • Genetic, biochemical, and structural studies of biogenesis of adhesive pili in bacteria. 
  • Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation. 
  • Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe. 
  • Global patterns in the biogeography of bacterial taxa. 
  • Glu-111 is required for activation of the DNA cleavage center of EcoRI endonuclease. 
  • Haemophilus influenzae pili are composite structures assembled via the HifB chaperone. 
  • High-frequency S-layer protein variation in Campylobacter fetus revealed by sapA mutagenesis. 
  • High-molecular-weight proteins of nontypable Haemophilus influenzae mediate attachment to human epithelial cells. 
  • Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface. 
  • Identification of a homogentisate-1,2-dioxygenase gene in the fungus Exophiala lecanii-corni: analysis and implications. 
  • Identification of a second family of high-molecular-weight adhesion proteins expressed by non-typable Haemophilus influenzae. 
  • Identification of two ancillary subunits of Escherichia coli type 1 fimbriae by using antibodies against synthetic oligopeptides of fim gene products. 
  • Impacts of silver nanoparticle coating on the nitrification potential of Nitrosomonas europaea. 
  • In vitro interactions of CysB protein with the cysJIH promoter of Salmonella typhimurium: inhibitory effects of sulfide. 
  • Indole-3-acetic acid biosynthesis is deficient in Gluconacetobacter diazotrophicus strains with mutations in cytochrome c biogenesis genes. 
  • Initiation of methyl-directed mismatch repair. 
  • Insights and inferences about integron evolution from genomic data. 
  • Interaction of dihydrofolate reductase with methotrexate: ensemble and single-molecule kinetics. 
  • Involvement of chlA, E, M, and N loci in Escherichia coli molybdopterin biosynthesis. 
  • Involvement of the S-layer proteins Hpi and SlpA in the maintenance of cell envelope integrity in Deinococcus radiodurans R1. 
  • Isolation and analysis of novel mutants of Escherichia coli prlA (secY). 
  • Isolation and characterization of the Escherichia coli mutL gene product. 
  • Liposome-mediated DNA uptake and transient expression in Thermotoga. 
  • Location of the host attachment site for phage HPl within a cluster of Haemophilus influenzae tRNA genes. 
  • Long-term monitoring of bacteria undergoing programmed population control in a microchemostat. 
  • Low-frequency infection of F- bacteria by transducing particles of filamentous bacteriophages. 
  • Mapping of rRNA genes with integrable plasmids in Bacillus subtilis. 
  • Mechanism of autophosphorylation of Escherichia coli nitrogen regulator II (NR(II) or NtrB): trans-Phosphorylation between subunits 
  • Mechanisms and biological effects of mismatch repair. 
  • Methyl-directed mismatch repair is bidirectional. 
  • Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon. 
  • Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein. 
  • Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth. 
  • Molecular characterization of the cysJIH promoters of Salmonella typhimurium and Escherichia coli: regulation by cysB protein and N-acetyl-L-serine. 
  • Molecular cloning of dimethyl sulfoxide reductase from Rhodobacter sphaeroides. 
  • Multidrug-binding transcription factor QacR binds the bivalent aromatic diamidines DB75 and DB359 in multiple positions. 
  • Multilaboratory evaluation of screening methods for detection of high-level aminoglycoside resistance in enterococci. National Committee for Clinical Laboratory Standards Study Group on Enterococci. 
  • MutL traps MutS at a DNA mismatch. 
  • Mutation detection with MutH, MutL, and MutS mismatch repair proteins. 
  • Myelin acquisition in the central nervous system of the mouse revealed by an MBP-Lac Z transgene. 
  • Negative autoregulation of cysB in Salmonella typhimurium: in vitro interactions of CysB protein with the cysB promoter. 
  • Niche partitioning among Prochlorococcus ecotypes along ocean-scale environmental gradients. 
  • Nonhomogeneous model of sequence evolution indicates independent origins of primary endosymbionts within the enterobacteriales (gamma-Proteobacteria). 
  • Nucleotide sequence of a gene cluster involved in entry of E colicins and single-stranded DNA of infecting filamentous bacteriophages into Escherichia coli. 
  • Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1. 
  • Organization of carboxysome genes in the thiobacilli. 
  • PCR identification of Mycobacterium bovis BCG. 
  • Phage Trojan horses: a conditional expression system for lethal genes. 
  • Phage fl mRNA processing in Escherichia coli: search for the upstream products of endonuclease cleavage, requirement for the product of the altered mRNA stability (ams) locus. 
  • Phylogeny of Wolbachia pipientis based on gltA, groEL and ftsZ gene sequences: clustering of arthropod and nematode symbionts in the F supergroup, and evidence for further diversity in the Wolbachia tree. 
  • Phylogeny of twenty Thermus isolates constructed from 16S rRNA gene sequence data. 
  • Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. 
  • Potential associations between severity of infection and the presence of virulence-associated genes in clinical strains of Staphylococcus aureus. 
  • Prevalence and distribution of the hmw and hia genes and the HMW and Hia adhesins among genetically diverse strains of nontypeable Haemophilus influenzae. 
  • Prevalence of 16S rRNA methylase genes in Enterobacteriaceae isolates from a Greek university hospital. 
  • Probing bacterial gene expression within host cells. 
  • Programmed population control by cell-cell communication and regulated killing. 
  • Properties of overlapping genes are conserved across microbial genomes. 
  • Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium. 
  • Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties. 
  • Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. 
  • Renaturation of cobra venom phospholipase A2 expressed from a synthetic gene in Escherichia coli. 
  • RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa. 
  • Sakacin P non-producing Lactobacillus sakei strains contain homologues of the sakacin P gene cluster. 
  • Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays. 
  • Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq. 
  • Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem. 
  • Staphylococcus aureus bacteremia at 5 US academic medical centers, 2008-2011: significant geographic variation in community-onset infections. 
  • Stepwise cloning and molecular characterization of the HgiDI restriction-modification system from Herpetosiphon giganteus Hpa2. 
  • Stoichiometry of binding of CysB to the cysJIH, cysK, and cysP promoter regions of Salmonella typhimurium. 
  • Structure and evolution of prokaryotic and eukaryotic RNA polymerases: a model. 
  • Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. 
  • Subspecific differentiation of Mycobacterium avium complex strains by automated sequencing of a region of the gene (hsp65) encoding a 65-kilodalton heat shock protein. 
  • Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement. 
  • The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development. 
  • The genetic determinant of adhesive function in type 1 fimbriae of Escherichia coli is distinct from the gene encoding the fimbrial subunit. 
  • The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions. 
  • The pterin molybdenum cofactors. 
  • The structure of the trpE, trpD and 5' trpC genes of Bacillus pumilus. 
  • The structure of the trpE, trpD and 5' trpC genes of Bacillus pumilus. 
  • Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes. 
  • TnphoA-mediated disruption of K54 capsular polysaccharide genes in Escherichia coli confers serum sensitivity. 
  • Trait-to-gene: a computational method for predicting the function of uncharacterized genes. 
  • Transcriptional pausing in a region important for plasmid NR1 replication control. 
  • Two proteins encoded at the chlA locus constitute the converting factor of Escherichia coli chlA1. 
  • Two tRNA gene clusters associated with rRNA operons rrnD and rrnE in Bacillus subtilis. 
  • Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation. 
  • Unprecedented loss of ammonia assimilation capability in a urease-encoding bacterial mutualist. 
  • Update on resistance of Bacteroides fragilis group and related species with special attention to carbapenems 2006-2009. 
  • Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization. 
  • Vertical transmission of biosynthetic plasmids in aphid endosymbionts (Buchnera). 
  • Vibrio metoecus sp. nov., a close relative of Vibrio cholerae isolated from coastal brackish ponds and clinical specimens. 
  • fii, a bacterial locus required for filamentous phage infection and its relation to colicin-tolerant tolA and tolB. 
  • lac repressor blocks in vivo transcription of lac control region DNA. 
  • mRNA processing in Escherichia coli: an activity encoded by the host processes bacteriophage f1 mRNAs. 
  • mig-14 is a horizontally acquired, host-induced gene required for salmonella enterica lethal infection in the murine model of typhoid fever. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Yang, Yiping, Professor of Medicine, Immunology
  • Zhang, Zhiquan, Assistant Professor in Anesthesiology, Anesthesiology