Genes, Fungal

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  Subject Areas on Research

  • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. 
  • A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii. 
  • A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans. 
  • A STE12 homolog is required for mating but dispensable for filamentation in candida lusitaniae. 
  • A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. 
  • A colony color method identifies the vulnerability of mitochondria to oxidative damage. 
  • A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. 
  • A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. 
  • A global meta-analysis of Tuber ITS rDNA sequences: species diversity, host associations and long-distance dispersal. 
  • A glucan synthase FKS1 homolog in cryptococcus neoformans is single copy and encodes an essential function. 
  • A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium. 
  • A multigene phylogenetic synthesis for the class Lecanoromycetes (Ascomycota): 1307 fungi representing 1139 infrageneric taxa, 317 genera and 66 families. 
  • A mutation of the yeast gene encoding PCNA destabilizes both microsatellite and minisatellite DNA sequences. 
  • A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. 
  • A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast. 
  • A single base substitution in the variable pocket of yeast tRNA(Arg) eliminates species-specific aminoacylation. 
  • A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states. 
  • A yeast cyclophilin gene essential for lactate metabolism at high temperature. 
  • A yeast expression system for human galactose-1-phosphate uridylyltransferase. 
  • Adenine auxotrophic mutants of Aspergillus oryzae: development of a novel transformation system with triple auxotrophic hosts. 
  • Allelic and ectopic interactions in recombination-defective yeast strains. 
  • Allelic and ectopic recombination between Ty elements in yeast. 
  • Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. 
  • Analysis of genes coding for small-subunit rRNA sequences in studying phylogenetics of dematiaceous fungal pathogens. 
  • Analysis of genes coding for small-subunit rRNA sequences in studying phylogenetics of dematiaceous fungal pathogens. 
  • Association of increased spontaneous mutation rates with high levels of transcription in yeast. 
  • Branching process deconvolution algorithm reveals a detailed cell-cycle transcription program. 
  • Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides. 
  • CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90. 
  • Ca(2+)/calmodulin-dependent kinase is essential for both growth and nuclear division in Aspergillus nidulans. 
  • Calcineurin governs thermotolerance and virulence of Cryptococcus gattii. 
  • Calcineurin is essential for survival during membrane stress in Candida albicans. 
  • Calcineurin is required for virulence of Cryptococcus neoformans. 
  • Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans. 
  • Calcium- and calcineurin-independent roles for calmodulin in Cryptococcus neoformans morphogenesis and high-temperature growth. 
  • Cdc28 tyrosine phosphorylation and the morphogenesis checkpoint in budding yeast. 
  • Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha. 
  • Characterization and expression of the unique calmodulin gene of Aspergillus nidulans. 
  • Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans. 
  • Characterization of the PMT gene family in Cryptococcus neoformans. 
  • Characterization of vps33+, a gene required for vacuolar biogenesis and protein sorting in Schizosaccharomyces pombe. 
  • Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes. 
  • Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. 
  • Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. 
  • Clonality and recombination in genetically differentiated subgroups of Cryptococcus gattii. 
  • Cloning and expression of the yeast plasma membrane ATPase in Escherichia coli. 
  • Cloning and sequence analysis of cnaA gene encoding the catalytic subunit of calcineurin from Aspergillus oryzae. 
  • Cloning the Cryptococcus neoformans TRP1 gene by complementation in Saccharomyces cerevisiae. 
  • Compact organization of rRNA genes in the filamentous fungus Ashbya gossypii. 
  • Comparative gene genealogical analyses of strains of serotype AD identify recombination in populations of serotypes A and D in the human pathogenic yeast Cryptococcus neoformans. 
  • Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection. 
  • Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans. 
  • Complex genetic interactions in a quantitative trait locus. 
  • Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. 
  • Conserved elements of the RAM signaling pathway establish cell polarity in the basidiomycete Cryptococcus neoformans in a divergent fashion from other fungi. 
  • Construction of a Recyclable Genetic Marker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides. 
  • Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. 
  • Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae. 
  • Cooperative regulation of cell proliferation by calcium and calmodulin in Aspergillus nidulans. 
  • Creation of an active estrogen-responsive element by a single base change in the flanking sequence of a cellular oncogene: a possible mechanism for hormonal carcinogenesis? 
  • Cryptococcus neoformans gene expression during experimental cryptococcal meningitis. 
  • Cryptococcus neoformans gene expression during murine macrophage infection. 
  • Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach. 
  • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. 
  • Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence. 
  • Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host. 
  • Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection. 
  • Cryptococcus neoformans: virulence and host defences. 
  • Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2. 
  • Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae. 
  • Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase. 
  • Cytosine deaminase MX cassettes as positive/negative selectable markers in Saccharomyces cerevisiae. 
  • DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae. 
  • DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast. 
  • Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae. 
  • Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. 
  • Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). 
  • Determinants of Swe1p degradation in Saccharomyces cerevisiae. 
  • Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus. 
  • Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating. 
  • Direct allelic variation scanning of the yeast genome. 
  • Discovery of a novel superfamily of type III polyketide synthases in Aspergillus oryzae. 
  • Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae. 
  • Dissecting the architecture of a quantitative trait locus in yeast. 
  • Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis. 
  • Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans. 
  • Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. 
  • Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans. 
  • Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae. 
  • Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae. 
  • Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus. 
  • Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. 
  • Evolution of budding yeast prion-determinant sequences across diverse fungi. 
  • Evolution of complex symbiotic relationships in a morphologically derived family of lichen-forming fungi. 
  • Evolution of pathogenicity and sexual reproduction in eight Candida genomes. 
  • Evolution under tight linkage to mating type. 
  • Expansions and contractions of the genetic map relative to the physical map of yeast chromosome III. 
  • Experimental determination of rates of concerted evolution. 
  • Extracellular cAMP is sufficient to restore developmental gene expression and morphogenesis in Dictyostelium cells lacking the aggregation adenylyl cyclase (ACA). 
  • Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans. 
  • FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. 
  • FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation. 
  • Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi. 
  • Full activation of p34CDC28 histone H1 kinase activity is unable to promote entry into mitosis in checkpoint-arrested cells of the yeast Saccharomyces cerevisiae. 
  • Functional analysis of the calcineurin-encoding gene cnaA from Aspergillus oryzae: evidence for its putative role in stress adaptation. 
  • Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. 
  • Fungal horizons: the Asilomar Fungal Genetics Conference 2007. 
  • Fungal mating-type loci. 
  • Fungal pathogenesis: gene clusters unveiled as secrets within the Ustilago maydis code. 
  • Fungal virulence genes as targets for antifungal chemotherapy. 
  • Gene Function Analysis in the Ubiquitous Human Commensal and Pathogen Malassezia Genus. 
  • Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae. 
  • Genes, Pathways, and Mechanisms Involved in the Virulence of Mucorales. 
  • Genetic evidence for preferential strand transfer during meiotic recombination in yeast. 
  • Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break. 
  • Genetic interactions among regulators of septin organization. 
  • Genetic manipulation of centromere function. 
  • Genetics of Cryptococcus neoformans. 
  • Genome sequencing and analysis of Aspergillus oryzae. 
  • Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase. 
  • Genus-Wide Comparative Genomics of Malassezia Delineates Its Phylogeny, Physiology, and Niche Adaptation on Human Skin. 
  • Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae. 
  • Group-I intron family in the nuclear ribosomal RNA small subunit genes of Cenococcum geophilum isolates. 
  • Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae. 
  • Heterotrimeric G-alpha subunits Gpa11 and Gpa12 define a transduction pathway that control spore size and virulence in Mucor circinelloides. 
  • High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae. 
  • High-throughput genome sequencing of lichenizing fungi to assess gene loss in the ammonium transporter/ammonia permease gene family. 
  • Historical biogeography and diversification of truffles in the Tuberaceae and their newly identified Southern hemisphere sister lineage 
  • Homozygous diploid deletion strains of Saccharomyces cerevisiae that determine lag phase and dehydration tolerance. 
  • INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype. 
  • Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity. 
  • Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarray. 
  • Identification of a Cryptococcus neoformans gene that directs expression of the cryptic Saccharomyces cerevisiae mannitol dehydrogenase gene. 
  • Identification of cell cycle-regulated, putative hyphal genes in Candida albicans. 
  • Identification of genes from the fungal pathogen Cryptococcus neoformans related to transmigration into the central nervous system. 
  • Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct. 
  • Identification of the sex genes in an early diverged fungus. 
  • Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. 
  • Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8. 
  • Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes. 
  • Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta. 
  • Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach. 
  • Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule. 
  • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. 
  • Isolation and characterization of effector-loop mutants of CDC42 in yeast. 
  • Isolation and functional analysis of sporulation-induced transcribed sequences from Saccharomyces cerevisiae. 
  • Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe. 
  • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. 
  • Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae. 
  • Light controls growth and development via a conserved pathway in the fungal kingdom. 
  • Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa. 
  • Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE. 
  • Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. 
  • Mechanisms that ensure monogamous mating in Saccharomyces cerevisiae. 
  • Meiotic recombination between dispersed repeated genes is associated with heteroduplex formation. 
  • Meiotic recombination within the centromere of a yeast chromosome. 
  • Messenger RNA intron in the nuclear 18s ribosomal RNA gene of deuteromycetes. 
  • Metatranscriptomic analysis of ectomycorrhizal roots reveals genes associated with Piloderma-Pinus symbiosis: improved methodologies for assessing gene expression in situ. 
  • Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast. 
  • Mitotic and meiotic gene conversion of Ty elements and other insertions in Saccharomyces cerevisiae. 
  • Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae. 
  • Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. 
  • Mitotic recombination within the centromere of a yeast chromosome. 
  • Molecular and genetic analysis of the Cryptococcus neoformans MET3 gene and a met3 mutant. 
  • Molecular approaches to identify novel targets for future development of antifungal agents. 
  • Molecular characterization of TRP1, a gene coding for tryptophan synthetase in the basidiomycete Coprinus cinereus. 
  • Molecular phylogeny of the Entomophthoromycota: 
  • Morphological and genomic characterization of Filobasidiella depauperata: a homothallic sibling species of the pathogenic cryptococcus species complex. 
  • Most of the yeast genomic sequences are not essential for cell growth and division. 
  • Multilocus microsatellite genotyping array for investigation of genetic epidemiology of Pneumocystis jirovecii. 
  • Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. 
  • Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium. 
  • Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. 
  • Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. 
  • Ninety-six haploid yeast strains with individual disruptions of open reading frames between YOR097C and YOR192C, constructed for the Saccharomyces genome deletion project, have an additional mutation in the mismatch repair gene MSH3. 
  • Novel Sfp1 transcriptional regulation of Saccharomyces cerevisiae gene expression changes during spaceflight. 
  • Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans. 
  • Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans. 
  • Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae. 
  • Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1. 
  • On the origins of congenic MATalpha and MATa strains of the pathogenic yeast Cryptococcus neoformans. 
  • Pathogenesis of Cryptococcus neoformans is associated with quantitative differences in multiple virulence factors. 
  • Pde1 phosphodiesterase modulates cyclic AMP levels through a protein kinase A-mediated negative feedback loop in Cryptococcus neoformans. 
  • Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans. 
  • Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition. 
  • Phosphorylation-independent inhibition of Cdc28p by the tyrosine kinase Swe1p in the morphogenesis checkpoint. 
  • Phylogenetic relationships in the mushroom genus Coprinus and dark-spored allies based on sequence data from the nuclear gene coding for the large ribosomal subunit RNA: divergent domains, outgroups, and monophyly. 
  • Phylogenomic analysis of non-ribosomal peptide synthetases in the genus Aspergillus. 
  • Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Physical lengths of meiotic and mitotic gene conversion tracts in Saccharomyces cerevisiae. 
  • Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. 
  • Polarity of meiotic gene conversion in fungi: contrasting views. 
  • Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. 
  • Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance. 
  • Proteogenomics produces comprehensive and highly accurate protein-coding gene annotation in a complete genome assembly of Malassezia sympodialis. 
  • Pseudohyphal growth of Cryptococcus neoformans is a reversible dimorphic transition in response to ammonium that requires Amt1 and Amt2 ammonium permeases. 
  • Rapid mapping of insertional mutations to probe cell wall regulation in Cryptococcus neoformans. 
  • Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment. 
  • Recombination between repeated genes in microorganisms. 
  • Recombination in yeast and the recombinant DNA technology. 
  • Reconstructing the early evolution of the Fungi using a six-gene phylogeny 
  • Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast. 
  • Reiterative Recombination for the in vivo assembly of libraries of multigene pathways. 
  • Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans. 
  • Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Role of Ca++/calmodulin binding proteins in Aspergillus nidulans cell cycle regulation. 
  • Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans. 
  • Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo. 
  • Role of phosphatidylinositol 3-phosphate in formation of forespore membrane in Schizosaccharomyces pombe. 
  • Roles for Stress Response and Cell Wall Biosynthesis Pathways in Caspofungin Tolerance in Cryptococcus neoformans. 
  • Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans. 
  • SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing. 
  • SP75 is encoded by the DP87 gene and belongs to a family of modular Dictyostelium discoideum outer layer spore coat proteins. 
  • Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. 
  • Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. 
  • Segregation of recombinant chromatids following mitotic crossing over in yeast. 
  • Separation of chromosomes of Cryptococcus neoformans by pulsed field gel electrophoresis. 
  • Sequences within the spacer region of yeast rRNA cistrons that stimulate 35S rRNA synthesis in vivo mediate RNA polymerase I-dependent promoter and terminator activities. 
  • Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi. 
  • Sexual Reproduction in Dermatophytes. 
  • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. 
  • Shared genetic pathways contribute to the tolerance of endogenous and low-dose exogenous DNA damage in yeast. 
  • Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformans. 
  • Ssk2 mitogen-activated protein kinase kinase kinase governs divergent patterns of the stress-activated Hog1 signaling pathway in Cryptococcus neoformans. 
  • Structural analysis of a yeast centromere. 
  • Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. 
  • Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway in Cryptococcus neoformans and contributes to fungal virulence. 
  • TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. 
  • TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. 
  • Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae. 
  • Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. 
  • The 40-kilodalton allergen of Candida albicans is an alcohol dehydrogenase: molecular cloning and immunological analysis using monoclonal antibodies. 
  • The Ascomycota tree of life: a phylum-wide phylogeny clarifies the origin and evolution of fundamental reproductive and ecological traits. 
  • The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome. 
  • The Cryptococcus neoformans capsule: a sword and a shield. 
  • The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p. 
  • The RNAi Mechanism Regulates a New Exonuclease Gene Involved in the Virulence of Mucorales. 
  • The Rho-GAP Bem2p plays a GAP-independent role in the morphogenesis checkpoint. 
  • The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects. 
  • The actin gene from Cryptococcus neoformans: structure and phylogenetic analysis. 
  • The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans. 
  • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. 
  • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. 
  • The chromosomal region containing pab-1, mip, and the A mating type locus of the secondarily homothallic homobasidiomycete Coprinus bilanatus. 
  • The gene encoding phosphoribosylaminoimidazole carboxylase (ADE2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid. 
  • The genetic structure and diversity of the A and B mating-type genes from the tropical oyster mushroom, Pleurotus djamor. 
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. 
  • The heterotrimeric G-protein beta subunit Gpb1 controls hyphal growth under low oxygen conditions through the protein kinase A pathway and is essential for virulence in the fungus Mucor circinelloides. 
  • The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. 
  • The morphogenesis checkpoint: how yeast cells watch their figures. 
  • The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. 
  • The rRNA-encoding DNA array has an altered structure in topoisomerase I mutants of Saccharomyces cerevisiae. 
  • The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle. 
  • The suppressor gene scl1+ of Saccharomyces cerevisiae is essential for growth. 
  • The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex. 
  • Three galactose inducible promoters for use in C. neoformans var. grubii. 
  • Three-dimensional image analysis of plugging at the septal pore by Woronin body during hypotonic shock inducing hyphal tip bursting in the filamentous fungus Aspergillus oryzae. 
  • Threonine biosynthetic genes are essential in Cryptococcus neoformans. 
  • Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators. 
  • Transactivation functions facilitate the disruption of chromatin structure by estrogen receptor derivatives in vivo. 
  • Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae. 
  • Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin. 
  • Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences. 
  • Transgene induced co-suppression during vegetative growth in Cryptococcus neoformans. 
  • Two proteins of the Dictyostelium spore coat bind to cellulose in vitro. 
  • Variation in modes and rates of evolution in nuclear and mitochondrial ribosomal DNA in the mushroom genus Amanita (Agaricales, Basidiomycota): phylogenetic implications. 
  • Verification of a new gene on Saccharomyces cerevisiae chromosome III. 
  • Virulence factors identified by Cryptococcus neoformans mutant screen differentially modulate lung immune responses and brain dissemination. 
  • Whole genome genetic-typing in yeast using high-density oligonucleotide arrays. 
  • Widespread occurrence of spliceosomal introns in the rDNA genes of ascomycetes. 
  • Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. 
  • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. 
  • cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I. 
  • crl mutants of Saccharomyces cerevisiae resemble both mutants affecting general control of amino acid biosynthesis and omnipotent translational suppressor mutants. 
  • vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly. 
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  Keywords of People

  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology