Genes, MHC Class I

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  Subject Areas on Research

  • A whole-genome association study of major determinants for host control of HIV-1. 
  • Altered growth of a human neuroendocrine carcinoma line after transfection of a major histocompatibility complex class I gene. 
  • Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 
  • Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung. 
  • Dendritic cell gene therapy. 
  • Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci. 
  • Donor-directed MHC class I antibody is preferentially cleared from sensitized recipients of combined liver/kidney transplants. 
  • Enumerating antigen-specific T-cell responses in peripheral blood: a comparison of peptide MHC Tetramer, ELISpot, and intracellular cytokine analysis. 
  • Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection. 
  • Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1. 
  • HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C. 
  • Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle. 
  • MHC class I-peptide interactions and TCR recognition. 
  • Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses. 
  • Modulation of the transformed and neoplastic phenotype of rat fibroblasts by MHC-I gene expression. 
  • Molecular clock and recombination in primate Mhc genes. 
  • Molecular diagnosis of Burkitt's lymphoma. 
  • Natural killer cell-endothelial cell interactions in xenotransplantation. 
  • Natural positive selection and north-south genetic diversity in East Asia. 
  • Partial suppression of anchorage-independent growth and tumorigenicity in immunodeficient mice by transfection of the H-2 class I gene H-2Ld into a human colon cancer cell line (HCT). 
  • Pharmacogenetics of toxic epidermal necrolysis. 
  • Polymorphisms in HLA class I genes associated with both favorable prognosis of human immunodeficiency virus (HIV) type 1 infection and positive cytotoxic T-lymphocyte responses to ALVAC-HIV recombinant canarypox vaccines. 
  • Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal. 
  • Recognition by and in vitro induction of cytotoxic T lymphocytes against predicted epitopes of the immediate-early protein ICP27 of herpes simplex virus. 
  • Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz. 
  • The canine MHC class Ia allele DLA-88*508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif. 
  • The relationship of modulation of major histocompatibility complex class I antigens to retrovirus transformation in rat cell lines. 
  • The role of KIR genes and their cognate HLA class I ligands in childhood acute lymphoblastic leukemia.