Genes, Regulator
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Subject Areas on Research
- A classification for genetic disorders of interest to orthopaedists.
- A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
- A genomic regulatory network for development.
- A highly complex organization of the regulatory region of the human CYP19 (aromatase) gene revealed by the Human Genome Project.
- A mouse homoeo box gene is expressed during embryogenesis and in adult kidney.
- A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo.
- A tripartite interaction among alleles of Notch, Delta, and Enhancer of split during imaginal development of Drosophila melanogaster.
- Activation of pmar1 controls specification of micromeres in the sea urchin embryo.
- Antisense oligonucleotides directed at cell cycle regulatory genes as strategy for restenosis therapy.
- Characterization of the DNase I hypersensitive site 3' of the human beta globin gene domain.
- Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.
- Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.
- Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes.
- Control of CD4 gene expression: connecting signals to outcomes in T cell development.
- Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights.
- Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system.
- Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer.
- Developmental regulation of mouse SPARC (osteonectin) gene expression.
- Developmental regulatory genes and echinoderm evolution.
- Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements.
- Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene.
- Evolutionary dissociations between homologous genes and homologous structures.
- Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature.
- Focus on butterfly eyespot development.
- Functional analysis of the transcription control region located within the avian retroviral long terminal repeat.
- Gene expression during echinoderm metamorphosis.
- Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli.
- Homoeo boxes and strings for the packaging of genes?
- Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine.
- Human erythrocyte antigens: II. The In(Lu) gene regulates expression of an antigen on an 80-kilodalton protein of human erythrocytes.
- Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein.
- Identification of a Cryptococcus neoformans gene that directs expression of the cryptic Saccharomyces cerevisiae mannitol dehydrogenase gene.
- Identification of a critical regulatory site in the human interleukin-3 promoter by in vivo footprinting.
- Identification of a muscle-specific enhancer within the 5'-flanking region of the human myoglobin gene.
- Identification of cis-acting repressor activity within human immunodeficiency virus type 1 protease sequences.
- Identification of potential regulatory regions in the renin gene.
- Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes.
- Isolation and initial characterization of the 5' flanking region of the human and murine cyclic guanosine monophosphate-phosphodiesterase beta-subunit genes.
- Lutheran antigens, CD44-related antigens, and Lutheran regulatory genes.
- Molecular biology of the renin-angiotensin system.
- Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.
- Neutral evolution of the nonbinding region of the anthocyanin regulatory gene Ipmyb1 in Ipomoea.
- Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells.
- Nucleotide pool in pho regulon mutants and alkaline phosphatase synthesis in Escherichia coli.
- Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains.
- Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression.
- Predictors of agr dysfunction in methicillin-resistant Staphylococcus aureus (MRSA) isolates among patients with MRSA bloodstream infections.
- RCC1, a regulator of mitosis, is essential for DNA replication.
- Radical alterations in the roles of homeobox genes during echinoderm evolution.
- Reconstructing regulatory network transitions.
- Regulation of the human c-myc gene: 5' noncoding sequences do not affect translation.
- Regulation of the human interleukin-3 gene.
- Regulation of transcription of the repA1 gene in the replication control region of IncFII plasmid NR1 by gene dosage of the repA2 transcription repressor protein.
- Regulatory and structural motifs of chicken gizzard myosin light chain kinase.
- Regulatory genes linked to the albino locus in the mouse confer competence for inducible expression on the structural gene encoding serine dehydratase.
- Relaxed selection among duplicate floral regulatory genes in Lamiales.
- Repressing a repressor: gibberellin-induced rapid reduction of the RGA protein in Arabidopsis.
- SV40 enhancer-binding factors are required at the establishment but not the maintenance step of enhancer-dependent transcriptional activation.
- Skeletal dysplasias and the growth plate.
- Structural basis of DNA-protein recognition.
- Suppression of leukaemia virus pathogenicity by polyoma virus enhancers.
- Synthesis of DNA coding for human proinsulin.
- TGF-beta related genes in development.
- The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA.
- The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root.
- The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance.
- The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus.
- The mast cell-specific expression of a protease gene, RMCP II, is regulated by an enhancer element that binds specifically to mast cell trans-acting factors.
- The myoD gene family: nodal point during specification of the muscle cell lineage.
- Thousands of human mobile element fragments undergo strong purifying selection near developmental genes.
- Transcription of a poxvirus early gene is regulated both by a short promoter element and by a transcriptional termination signal controlling transcriptional interference.
- Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity.
- Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region.
- Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.
- Transposed LEU2 gene of Saccharomyces cerevisiae is regulated normally.
- Waiting for two mutations: with applications to regulatory sequence evolution and the limits of Darwinian evolution.
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Keywords of People
- Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
- Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology