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Subject Areas on Research
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A canarypox vaccine expressing multiple human immunodeficiency virus type 1 genes given alone or with rgp120 elicits broad and durable CD8+ cytotoxic T lymphocyte responses in seronegative volunteers.
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A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses.
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A morphological analysis endocrine tumour genesis in pancreas and anterior pituitary of AVP/SV40 transgenic mice.
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A system of transposon mutagenesis for bacteriophage T4.
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Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.
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Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation.
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Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.
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Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism.
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Ancient co-speciation of simian foamy viruses and primates.
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Association of 3' terminal RNA sequences with avian leukosis viruses causing a high incidence of osteopetrosis.
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B-MuX: a unique murine C-type virus containing the "env" gene of xenotropic viruses and the "gag" gene of the ecotropic virus.
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Bacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coli.
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Base mutations in the terminal noncoding regions of the genome of vesicular stomatitis virus isolated from persistent infections of L cells.
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Bioaerosol Sampling for Respiratory Viruses in Singapore's Mass Rapid Transit Network.
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Biochemistry and Molecular Biology of Flaviviruses.
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Biological, immunological, and biochemical evidence that HIX virus is a recombinant between Moloney leukemia virus and a murine xenotropic C type virus.
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CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes.
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Cassettes of the f1 intergenic region.
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Characterization of the transcriptional trans activator of human foamy retrovirus.
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Chimeric alphavirus vaccine candidates for chikungunya.
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Clonal isolate of the simian sarcoma virus codes for a Gag-related 65,000-dalton protein.
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Cloning of the terminal loop of vaccinia virus DNA.
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Comparison of the genomes of the wild-type French viscerotropic strain of yellow fever virus with its vaccine derivative French neurotropic vaccine.
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Complete genomic nucleotide sequence of the temperate bacteriophage Aa Phi 23 of Actinobacillus actinomycetemcomitans.
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Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes.
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Conservation of the 3' terminal nucleotide sequences of Ebola and Marburg virus.
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Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant: further clarifications.
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Convergent evolution of escape from hepaciviral antagonism in primates.
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Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex.
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Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.
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Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB, that binds TNF but not LT alpha.
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Current status and strategies for vaccines against diseases induced by human T-cell lymphotropic retroviruses (HTLV-I, -II, -III).
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Deletion of the essential gene 24 from the bacteriophage T4 genome.
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Development of a vaccine for the prevention of AIDS, a critical appraisal.
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Development of an env gp41-based heteroduplex mobility assay for rapid human immunodeficiency virus type 1 subtyping.
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Dicistronic polioviruses as expression vectors for foreign genes.
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Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate.
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ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system.
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Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape.
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Effects of the src gene product on microfilament and microtubule organization in avian and mammalian cells infected with the same temperature-sensitive mutant of Rous sarcoma virus.
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Effects of tumor growth on host defenses.
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Endogenous avian retroviruses contain deficient promoter and leader sequences.
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Evolutionary implications of primate endogenous retroviruses.
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Expression and function of the uvsW gene of bacteriophage T4.
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Extended ORF8 Gene Region Is Valuable in the Epidemiological Investigation of Severe Acute Respiratory Syndrome-Similar Coronavirus.
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Fine structure mapping and phenotypic analysis of five temperature-sensitive mutations in the second largest subunit of vaccinia virus DNA-dependent RNA polymerase.
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From the Institute of Medicine.
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Functional analysis of the transcription control region located within the avian retroviral long terminal repeat.
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Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species.
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Fusion of the termini of the murine cytomegalovirus genome after infection.
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Generation of reovirus core-like particles in cells infected with hybrid vaccinia viruses that express genome segments L1, L2, L3, and S2.
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Genetic recombination of poliovirus in a cell-free system.
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Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins.
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Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice.
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HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC.
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HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence.
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HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency.
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Hemorrhage in lesions caused by cowpox virus is induced by a viral protein that is related to plasma protein inhibitors of serine proteases.
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Human immunodeficiency virus as a prototypic complex retrovirus.
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Humoral immune response to the entire human immunodeficiency virus envelope glycoprotein made in insect cells.
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ICP34.5-dependent and -independent activities of salubrinal in herpes simplex virus-1 infected cells.
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Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter.
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Identification of cis-acting repressor activity within human immunodeficiency virus type 1 protease sequences.
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Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes.
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Inhibition of an inflammatory response is mediated by a 38-kDa protein of cowpox virus.
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Inhibition of human immunodeficiency virus Rev and human T-cell leukemia virus Rex function, but not Mason-Pfizer monkey virus constitutive transport element activity, by a mutant human nucleoporin targeted to Crm1.
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Intervening sequence between the leader region and the nucleopcapsid gene of vesicular stomatitis virus RNA.
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Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells.
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Light-inducible gene regulation with engineered zinc finger proteins.
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Localization and characterization of the src-gene product of Rous sarcoma virus.
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Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.
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Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene.
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Mechanism of action of regulatory proteins encoded by complex retroviruses.
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Messenger RNAs of a strongly-expressed late gene of cowpox virus contain 5'-terminal poly(A) sequences.
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Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome (Smith Strain).
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Multiple gene segments control the temperature sensitivity and attenuation phenotypes of ca B/Ann Arbor/1/66.
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Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component.
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Murine cytomegalovirus gene amplification and culture after submaxillary salivary gland biopsy.
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Mutational alteration of the breakage/resealing subunit of bacteriophage T4 DNA topoisomerase confers resistance to antitumor agent m-AMSA.
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Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat.
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Nature of the 3'-terminal sequences of the plus and minus strands of the S1 gene of reovirus serotypes 1, 2 and 3.
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Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells.
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Novel circular DNA viruses in stool samples of wild-living chimpanzees.
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Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert.
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Nucleotide bias of DCL and AGO in plant anti-virus gene silencing.
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Nucleotide sequence and host La protein interactions of rabies virus leader RNA.
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Nucleotide sequence of the envelope protein genes of a highly virulent, neurotropic strain of Newcastle disease virus.
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Parallel molecular evolution of deletions and nonsense mutations in bacteriophage T7.
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Patterns of regulation from mRNA and protein time series.
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Phage T3 DNA contains an exact copy of the 23 base-pair phage T7 RNA polymerase promoter sequence.
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Photosynthesis genes in marine viruses yield proteins during host infection.
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Phylogenetic analysis of protease and transmembrane region of HIV type 1 group O.
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Plasmid models for bacteriophage T4 DNA replication: requirements for fork proteins.
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Plasmids for recombination-based screening.
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Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction.
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Polycistronic vesicular stomatitis virus RNA transcripts.
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Positive-selection cloning vehicle useful for overproduction of hybrid proteins.
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Prevalence of human papillomavirus types 16 and 18 in squamous-cell carcinoma of the penis: a retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction.
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Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein.
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Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted.
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Protective efficacy of a single immunization of a chimeric adenovirus vector-based vaccine against simian immunodeficiency virus challenge in rhesus monkeys.
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Purified MotA protein binds the -30 region of a bacteriophage T4 middle-mode promoter and activates transcription in vitro.
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RNA interference and single particle tracking analysis of hepatitis C virus endocytosis.
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RNA polymerase-associated interactions near template promoter sequences of defective interfering particles of vesicular stomatitis virus.
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RNA sequence and transcriptional properties of the 3' end of the Newcastle disease virus genome.
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Recombinant DNA Advisory Committee. Department of Health and Human Services. National Institutes of Health. Minutes of meeting. December 15-16, 1997.
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Recombination hotspots in bacteriophage T4 are dependent on replication origins.
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Regulatory pathways governing HIV-1 replication.
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Replication of the vesicular stomatitis virus genome in permissive and nonpermissive host cells.
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Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells.
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Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus.
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Rev activates expression of the human immunodeficiency virus type 1 vif and vpr gene products.
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Role of the avian retrovirus mRNA leader in expression: evidence for novel translational control.
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Selectivity of interferon action in simian virus 40-transformed cells superinfected with simian virus 40.
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Sequence at both termini of the 10 genes of reovirus serotype 3 (strain Dearing).
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Sequence-specific contacts between the RNA polymerase of vesicular stomatitis virus and the leader RNA gene.
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Sequential synthesis of small capped RNA transcripts in vitro by vesicular stomatitis virus.
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Site on the vesicular stomatitis virus genome specifying polyadenylation and the end of the L gene mRNA.
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Site-specific integration of the Haemophilus influenzae bacteriophage HP1. Identification of the points of recombinational strand exchange and the limits of the host attachment site.
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Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants.
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Site-specific recognition of bacteriophage T4 DNA by T4 type II DNA topoisomerase and Escherichia coli DNA gyrase.
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Sites of copy choice replication involved in generation of vesicular stomatitis virus defective-interfering particle RNAs.
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Specific transforming potential of oncogenes encoding protein-tyrosine kinases.
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Spontaneous deletions and duplications of sequences in the genome of cowpox virus.
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Structure and morphogenesis of type-C retroviruses.
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Superimmunity: characterization of a new gene in the immunity region of P1.
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T7-induced DNA polymerase. Characterization of associated exonuclease activities and resolution into biologically active subunits.
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Tandemly repeated sequences are present at the ends of the DNA of raccoonpox virus.
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The HIV cytopathic effect: potential target for therapy?
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The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters.
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The complete sequence of a unique RNA species synthesized by a DI particle of VSV.
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The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines.
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The cutaneous T cell lymphoma, mycosis fungoides, is a human T cell lymphotropic virus-associated disease. A study of 50 patients.
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The expression of viral and cellular genes in papillomas of the choroid plexus induced in transgenic mice.
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The mode of death of pig kidney cells infected with cowpox virus is governed by the expression of the crmA gene.
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The natural 5' splice site of simian virus 40 large T antigen can be improved by increasing the base complementarity to U1 RNA.
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The origins of defective interfering particles of the negative-strand RNA viruses.
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The plus strand of reovirus gene S2 is identical with its in vitro transcript.
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The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation.
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The products of gene I and the overlapping in-frame gene XI are required for filamentous phage assembly.
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The role of avian retroviral LTRs in the regulation of gene expression and viral replication.
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The roles of the bacteriophage T4 r genes in lysis inhibition and fine-structure genetics: a new perspective.
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The second-largest subunit of the poxvirus RNA polymerase is similar to the corresponding subunits of procaryotic and eucaryotic RNA polymerases.
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The self-cleaving domain from the genomic RNA of hepatitis delta virus: sequence requirements and the effects of denaturant.
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The sequence at the termini of four genes of the three reovirus serotypes.
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The sequences of reovirus serotype 3 genome segments M1 and M3 encoding the minor protein mu 2 and the major nonstructural protein mu NS, respectively.
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Toward a vaccine against AIDS: rationale and current progress.
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Transcription of a poxvirus early gene is regulated both by a short promoter element and by a transcriptional termination signal controlling transcriptional interference.
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Transcription of orthopoxvirus telomeres at late times during infection.
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Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus.
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UvsW protein regulates bacteriophage T4 origin-dependent replication by unwinding R-loops.
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Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles.
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Vaccinia virus directs the synthesis of early mRNAs containing 5' poly(A) sequences.
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Vesicular stomatitis virus defective interfering particle containing a muted internal leader RNA gene.
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Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection.
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Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme.
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Viral sequences determining the oncogenicity of avian leukosis viruses.
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Visna virus encodes a post-transcriptional regulator of viral structural gene expression.
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Keywords of People