Germ Cells
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Subject Areas on Research
- A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.
- A mitotic recombination system for mouse chromosome 17.
- A role for Pin1 in mammalian germ cell development and spermatogenesis.
- A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration.
- A zebrafish model of germ cell aneuploidy.
- BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.
- Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations.
- Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
- Bmp7 regulates germ cell proliferation in mouse fetal gonads.
- Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse.
- Cell fate commitment during mammalian sex determination.
- Chondrogenic differentiation of human embryonic germ cell derived cells in hydrogels.
- Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary.
- Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells.
- E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells.
- Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture.
- Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit.
- Embryonic germ cell lines and their derivation from mouse primordial germ cells.
- Embryonic germ cells are capable of adipogenic differentiation in vitro and in vivo.
- Engineering musculoskeletal tissues with human embryonic germ cell derivatives.
- Establishment and characterization of conditionally immortalized cells from the mouse urogenital ridge.
- Expression and functional analysis of Gm114, a putative mammalian ortholog of Drosophila bam.
- FGF9 promotes survival of germ cells in the fetal testis.
- Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis.
- Four-dimensional analysis of vascularization during primary development of an organ, the gonad.
- Genetic dissection of late-life fertility in Caenorhabditis elegans.
- Germ cell depletion does not alter the morphogenesis of the fetal testis or ovary in the red-eared slider turtle (Trachemys scripta).
- Germ cells are not required to establish the female pathway in mouse fetal gonads.
- Germline sequences of V(H)7183 gene family members in C57BL/6 mice demonstrate natural selection of particular sequences during recent evolution.
- Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans.
- Germline transcription: a key regulator of accessibility and recombination.
- HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence.
- Identification of regulators of germ stem cell enwrapment by its niche in C. elegans.
- Insulin-like signalling to the maternal germline controls progeny response to osmotic stress.
- Karyotypic abnormalities create discordance of germline genotype and cancer cell phenotypes.
- Measurement and modulation of nonoxynol-9 diffusion and bioactivity against spermatozoa in human cervical mucus.
- Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads.
- Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.
- Mouse germ cell clusters form by aggregation as well as clonal divisions.
- Mouse primordial germ cells. Isolation and in vitro culture.
- Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling.
- Pathogenic Germline Variants in 10,389 Adult Cancers.
- Pin1 regulates the timing of mammalian primordial germ cell proliferation.
- Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing.
- Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters.
- Sex in fungi.
- Signaling at the crossroads of gonad development.
- Stem cells and their niches: integrated units that maintain Drosophila tissues.
- Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad.
- Testicular germ-cell apoptosis in stressed rats following combined exposure to pyridostigmine bromide, N,N-diethyl m-toluamide (DEET), and permethrin.
- Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis.
- The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis.
- The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.
- To grow or not to grow: nutritional control of development during Caenorhabditis elegans L1 arrest.
- Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity.
- Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development.
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Keywords of People
- Baugh, L. Ryan, Associate Professor of Biology, Biology
- Katz, David F., Nello L. Teer, Jr. Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering, Biomedical Engineering
- Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology