Glucosyltransferases
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Subject Areas on Research
- A glucan synthase FKS1 homolog in cryptococcus neoformans is single copy and encodes an essential function.
- A survey of plant and algal genomes and transcriptomes reveals new insights into the evolution and function of the cellulose synthase superfamily.
- Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates.
- Breakthrough invasive candidiasis in patients on micafungin.
- Central Role of the Trehalose Biosynthesis Pathway in the Pathogenesis of Human Fungal Infections: Opportunities and Challenges for Therapeutic Development.
- Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans.
- Chlamydospore formation during hyphal growth in Cryptococcus neoformans.
- Combining expression and comparative evolutionary analysis. The COBRA gene family.
- Distinct cell-specific expression patterns of early and late gibberellin biosynthetic genes during Arabidopsis seed germination.
- Dolichyl-phosphate-glucose is used to make O-glycans on glycoproteins of Trichomonas vaginalis.
- Dysregulation of multiple facets of glycogen metabolism in a murine model of Pompe disease.
- Evolutionary rate variation in anthocyanin pathway genes.
- Flux control in a plant defense pathway is robust to environmental perturbations and controls variation in adaptive traits
- Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds.
- Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata.
- Glucose availability and glycolytic metabolism dictate glycosphingolipid levels.
- Glyco-engineering in Archaea: differential N-glycosylation of the S-layer glycoprotein in a transformed Haloferax volcanii strain.
- Glycogen debranching enzyme: purification, antibody characterization, and immunoblot analyses of type III glycogen storage disease.
- Glycolipids and glycosyltransferases in permanent cell lines established from human medulloblastomas.
- HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells.
- Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations.
- Length Specificity and Polymerization Mechanism of (1,3)-β-d-Glucan Synthase in Fungal Cell Wall Biosynthesis.
- Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients.
- Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development.
- Patterns of evolutionary rate variation among genes of the anthocyanin biosynthetic pathway.
- Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide.
- Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
- The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii.
- Timely Endocytosis of Cytokinetic Enzymes Prevents Premature Spindle Breakage during Mitotic Exit.
- Trehalose pathway as an antifungal target.
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Keywords of People
- Shinohara, Mari L., Professor of Integrative Immunobiology, Cell Biology