Glutaminase
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Subject Areas on Research
- A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer.
- Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
- Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations.
- Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma.
- Glutamine Metabolism in Cancer: Understanding the Heterogeneity.
- Glutamine metabolism during aerial mycelium growth of Neurospora crassa.
- Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia.
- Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.
- Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia.
- Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.
- Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer.
- Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.
- Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
- Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells.
- Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.